BibliografĂa
El-Mir, M.Y., Nogueira, V., Fontaine, E., Averet, N., Rigoulet, M., and Leverve, X. (2000). Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I. J Biol Chem 275, 223-228. Esterbauer, H., Schneitler, C., Oberkofler, H., Ebenbichler, C., Paulweber, B., Sandhofer, F., Ladurner, G., Hell, E., Strosberg, A.D., Patsch, J.R., et al. (2001). A common polymorphism in the promoter of UCP2 is associated with decreased risk of obesity in middle-aged humans. Nature genetics 28, 178-183. Fantuzzi, G. (2005). Adipose tissue, adipokines, and inflammation. J Allergy Clin Immunol 115, 911-919; quiz 920. Fato, R., Bergamini, C., Leoni, S., and Lenaz, G. (2008). Mitochondrial production of reactive oxygen species: role of complex I and quinone analogues. Biofactors 32, 31-39. Festa, A., D'Agostino, R., Jr., Williams, K., Karter, A.J., Mayer-Davis, E.J., Tracy, R.P., and Haffner, S.M. (2001). The relation of body fat mass and distribution to markers of chronic inflammation. Int J Obes Relat Metab Disord 25, 1407-1415. Fleury, C., Neverova, M., Collins, S., Raimbault, S., Champigny, O., Levi-Meyrueis, C., Bouillaud, F., Seldin, M.F., Surwit, R.S., Ricquier, D., et al. (1997). Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia. Nature genetics 15, 269-272. Fleury, C., Mignotte, B., and Vayssiere, J.L. (2002). Mitochondrial reactive oxygen species in cell death signaling. Biochimie 84, 131-141. Forman, H.J., Zhang, H., and Rinna, A. (2009). Glutathione: overview of its protective roles, measurement, and biosynthesis. Mol Aspects Med 30, 1-12. Formoso, G., De Filippis, E.A., Michetti, N., Di Fulvio, P., Pandolfi, A., Bucciarelli, T., Ciabattoni, G., Nicolucci, A., Davi, G., and Consoli, A. (2008). Decreased in vivo oxidative stress and decreased platelet activation following metformin treatment in newly diagnosed type 2 diabetic subjects. Diabetes Metab Res Rev 24, 231-237. Fridovich, I. (1997). Superoxide anion radical (O2-.), superoxide dismutases, and related matters. J Biol Chem 272, 18515-18517. Friedman, J.M. (2009). Leptin at 14 y of age: an ongoing story. Am J Clin Nutr 89, 973S979S. Fryer, L.G., Parbu-Patel, A., and Carling, D. (2002). The Anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways. J Biol Chem 277, 25226-25232. Gaidhu, M.P., Fediuc, S., and Ceddia, R.B. (2006). 5-Aminoimidazole-4-carboxamide-1beta-D-ribofuranoside-induced AMP-activated protein kinase phosphorylation inhibits basal and insulin-stimulated glucose uptake, lipid synthesis, and fatty acid oxidation in isolated rat adipocytes. J Biol Chem 281, 25956-25964. Gaidhu, M.P., Fediuc, S., Anthony, N.M., So, M., Mirpourian, M., Perry, R.L., and Ceddia, R.B. (2009). Prolonged AICAR-induced AMP-kinase activation promotes energy
181