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Land of opportunities for biosciences startup companies

Bilbao Bizkaia Startup


Strengths and drivers of Bilbao Bizkaia for biosciences startups

Strengths

Drivers

1

Macroeconomic Situation

1

Entrepeneur driven public institutions

2

Strategical Position

2

Friendly towards investment

3

Market Strength

3

Biosciences Incubators, space for entrepreneurs

4

R&D&i

4

Investment, introducing your best partners

5

Human Capital

5

Access to the most talented human capital

6

Infrastructures and Connectivity

6

International events related to biosciences economy

7

Working and Living in Biscay

7

Public advisory, all you need is us


Strengths of Bilbao Bizkaia for Biosciences startups


1. Macroeconomic Situation

Population

Metropolitan Bilbao: 1,100,000

Foreign population

7%

GDP per capita

â‚Ź 28,461

122% EU average

Biosciences companies

70 Basque companies

Employment in biosciences industry

26,500


2. Strategical Position

Thanks to its location in the European Union, Bilbao Bizkaia is a strategic hub for the establishment of your biosciences startup

Direct flights to European cities Paris London Brussels Berlin Frankfurt Munich Dusseldorf Sttutgart Milan Rome Oslo Lisbon Amsterdam Barcelona Madrid Istanbul Geneva Manchester


3. Market Strength

Spain´s 3rd strongest region for foreign direct investment, behind Madrid and Catalonia

700 Almost 700 foreign companies settled in the Basque Country

1000 M

13

20

12 20

11 20

10 20

09 20

08

People Employed in FDI companies = 11% of working population

500 M

20

61.000

999 M Basque Gross Investment Flow


3. Market Strength

Basque Biocluster exerts itself to stay a dynamic and open association that reflects the goals of its members

Almost

300

companies involved

BASQUE BIOCLUSTER

1,632

employees

268M turnover

211M exports

31M

investment R&D&i

Health-related (human or animal) biotechnologies

Bio-solutions for agro/food chains and environmental safety

Advanced materials and engineering

Turn-key lab/plant construction and systems


4. R&D&i Advanced science, technology and innovation system.

Technology Park of Bizkaia Workforce

7,647

R&D employees

27%

Global income

â‚Ź 2,455 mill.

Re s

219

Supporting infraestructures

Universities

on

Stablished companies

evelopment & In D & no h va c r a ti 4 3 e 9

Basic & excelence research centres

28 Intermediate bodies

Innovation Support Sub System

University and Scientifici Sub-System

7 Centres for cooperative research

ue

Eco

64

syste

19 Technological centres

n m : Bi o s ci e

ce

r

sq

Research & innovaction bussiness units

to

â‚Ź 170 mill.

More than per year allocated for Research, Development and Innovation in Bilbao Bizkaia

Technological Development Sub-System

14

Ba

First region in Spain according to GDP Invested in R&D&i 2,19% Above EU 2020 objectives

Laboratories & health r+d centres

e sS

c


4. R&D&i Specialised Technology and Research Centres: key factor in industrial competitiveness Technology Centres

123Mâ‚Ź

1,831

turnover

Staff Members

335

1,280

patents

Research Centres

145 105Mâ‚Ź

patents

turnover

researchers

1,310

Staff Members

CIC bioGUNE CIC biomaGUNE CIC microGUNE CIC nanoGUNE BIOEF Biocruces Onkologikoa, cancer CITA, Alzheimer Inbiomed, Regenerative Medicine

Key research areas: Personalised medicine and diagnostics.

Regenerative medicine.

Drug discovery.

Medical and CNS & different surgical devices. diseases

Biosensors and analytics.

Equipment and instrumentation.

Agrochemical uses of Biotechnology.


5. Human Capital

The Basque University Education is referent within the European Higher Education Area.

Deusto

MONDRAGON UNIBERTSITATEA

3rd European Region with the highest number of university graduates

67,551 University Students 8,769 biosciences sector related university studies

Young people with university degree

Bizkaia 43% Europe 24%


5. Human Capital

Degree

• • • • • • • • • •

Biology Biochemistry and Molecular Biology Biotechnology Science and Food Technology Environmental Sciences Physics Geology Mathematics Chemistry Medicine

• • • • • • • • •

Master

• • • • • • •

Forensic analysis Biomedical engineering Biomedical research Microbiology and health Molecular biology and biomedicine Neuroscience Pharmacology, development, evaluation and rational use of medicines Food quality and safety Nutrition and health Applied chemistry and polymeric materials Nanoscience New materials Physics and materials technologies Synthetic and industrial chemistry

• Theoretical chemistry and computational modelling • Advanced materials engineering • Chemical engineering • Control engineering, automation and robotics • Engineering physics • Environmental engineering • Renewable materials engineering • Research in environmental engineering • Photovoltaic devices and systems • Sustainable energy engineering

• • • • • • •

Human Nutrition and Dietetics Dentistry Nursing Pharmacy Environmental Engineering Chemical Engineering Industrial Chemical Engineering Manufacturing Ecotechnologies Biomedical Engineering

Deusto

MONDRAGON UNIBERTSITATEA


6. Infrastructures and connectivity

Metro & city tram

Network of railway lines

Road connections

Bilbao international airport

Metro and tram:

High Speed Train,

Road Connections:

Airport:

1.000 million users per year. Three minutes frequency. Complete coverage of metropolitan area.

will start operating in 2018: Madrid in 2 hours, Paris 5 hours.

Excellent transport links, which connects all municipalities in less than 40 minutes by road or public transport.

more than 4 million passengers per year. 10 minutes from Bilbao city center (12 Km).


6. Infrastructures and connectivity

Innovative infrastructures at the service of talent Animal facilities and animal models Cell Reprogramming and Differentiation core facility Structural Biology Platform (NMR, protein crystallisation, X-ray, electron microscopy) Pharma and biomanufacturing Basque Biobank, O+ehun (brains, tumours, peripheral blood - DNA, RNA, etc. - and other fluids) Metabolomics platform, mass spectrometry based Inbiobank (adult stem cells and primary cells), node of the National Bank of Cell Lines Genome analysis and gene silencing platforms Proteomics core facilities Molecular Imaging Facility (radiochemistry, MRI, SPECT, PET, CT, optical tomography) Dedicated biomedical Effectiveness Demonstration Unit and other clinical resources


6. Infrastructures and connectivity Cutting edge TIC infrastructures that cover all Bilbao-Bizkaia.

88% of the population access NGAs and 3G /4G technologies.

â‚Ź 72 mill. public budget allocated for the digital agenda.

Secure and trustable network

Cloud Computing boosted from the public institutions

Broad Band access 95% of the population


7. Working and Living in Bilbao-Bizkaia

1st

LivCom Prize in the category of Enhancement of the Natural and Built Landscapes

• High quality health care • Longest life expectancy in the EU. • Free and universal health system, reference as a quality service.

78,2 85,1 1st

1

st

Lee Kuan Yew World City Prize 2010 (Nobel Prize of Cities)

Best Urban Practices Award (Expo 2010)

1st

• Human Development Index Bizkaia • Above UE average rate, 0,738.

Città d´Acqua, Biennale di Venezia Architecture


7. Working and Living in Bilbao-Bizkaia

Culture 1 M annual visitors at Guggenheim Museum

Nature Beach 10 minutes away from city centre

Cultural Assets declared World Heritage by UNESCO

Bilbao is a reference in the European Art Network, and it complements the Bilbao-Bordeaux-Madrid Ant Axis.

Gastronomy 28 Michelin Stars in 2014

Bilbao is the 3rd most sustainable City in Spain 53% of its surface covered with trees. Natural Assets declared as Biosphere Reserve by UNESCOÂ


Drivers for a biosciences startup in Bilbao Bizkaia


1. Entrepreneur driven public institutions

1st

City with the best e-Administration in Spain according to the Internet Users Association (2010)

Openness

1st

Most transparent city in Spain in 2008, 2009, 2011 and 2012 according to Transparency International

Transparency

1st

Rigorous economic policies and strategic budget to ensure a stable economic network (zero debt, paid in 30 days)

4

th

Security

Southern European city in the overall and FDI strategy categories in the FDI European Cities and regional of the future ranking (2014)

Investment

Winner of the EPSA-European Public Service Award (2011)


1. Entrepreneur driven public institutions

Three public companies committed to digital contents startups in Bilbao Bizkaia.

Advice in obtaining licenses and permits Obtaining visa Connectivity Trademark Patenting

A consultant beside you 24/7 Funding & subsidies Constitution (PAE) Location Advisory Hiring

Centralised Point to help entrepreneurs Expedited incorporation: 2-3 days. Cheap incorporation: 100 â‚Ź Accompanying notary signature Administrative documentation Advice on legal forms


2. Friendly towards investment

Bizkaia legislates on direct taxes and establishes tax incentives and deductions for its businesses. Research Development 30-50% General tax 28%

New Non-Current Assets 10% (5% in asset improvement) Projects involving sustainable taxation 10-30%

Reduced to 24% for SMEs

Patent Box 30-60% (acquired or developed) Creation of employment 4,900€ per person Incentives related to funding (all companies)

Tax Deductions

Technological Innovation 15-20% (with Technological Centres) Tax Incentives for companies investing in startups: • Reduction in the tax base (60% of the invested amount) • Purchase of shares: maximum 100.000€ per investment


3. Biosciences Incubators, space for entrepreneurs

An advanced business incubator specialised in value added sectors Specialitation High Value added sectors and technologies: Bio-micronano technologies, Clean technologies and Advanced manufacturing

Installations Fully equiped with workrooms and laboratories for the development of the industrial and research activities.

Services

Kabi 612.

Focused on the growth 5.600m2 (4.5â‚Ź/m2/month) and 20MB the continuity of the companies: Elkartegiak. Acceleration, access (3-9â‚Ź/m2/month) 20MB to experts, training, investment rounds.


4. Investment, introducing your best partners

Specific public funding for every stage of the company life cycle. VCs Acquisitions/Mergers & Strategic Alliances Early Stage

250k

5,000-4,0000k Ekarpen

Later Stage

REVENUE

Gaitek

Angels, FFF Seed Capital

1500k 500k

Ekintzaile XXI

Ezten

400k

250k

Seed Capital Bizkaia

Pre-Seed Capital

95k

Incorporation

110k

project concept

180k

Corporate constitution

Valley of Death

Etorgai

Bideratu

Gauzatu

2,000k

1,000k

1,000k 50k

70k

Innovative Equipment projects Purchase

250k

Elkartzen

Basque Fondo II

120k

Internationalisation

500k Lanpar

500k

Elkano XXI

25k

Micro credits

100k

Basque Fondo

Grant TIME

Loan Capital

* Maximum amounts for each funding tool. Some of them would be subject to the European minimis rule.


4. Investment, introducing your best partners

Private funding agents in Bilbao Bizkaia are extremely proactive in searching startups to invest in. Private investment funds operating in Bilbao Bizkaia:

VCs Acquisitions/Mergers & Strategic Alliances Early Stage Angels, FFF

REVENUE

Seed Capital

>150k

CDTI Innovation

200k

Business Angels Network

Seed Funds

Later Stage

50k

Financial Entities

300k 150k

1,500k

Mutual Guarantee Societies

250k

Specialised funds

START DMC Argi Industrial Partners / UPLIFT S.L. MicroWave Ventures Emprendiza Samsung Venture Investment Kereon partners Abra Invest S.L. Crecer + Bulka Business Angels Inception Onza Vitamina k Entrecanales Sitka Capital Faraday Ventures Partners OnetoOne Corporate Finance DUMA Asociados Talde Ekarpen Caixa Capital Risk

ENISA

Entrepeneurs

25k

Social Entities

Endorsament Valley of Death

TIME * Maximum amounts for each funding tool. Some of them would be subjet to the European minimis rule.

Loan Capital


4. Investment, introducing your best partners Financial institutions in Bilbao-Bizkaia offer much more than just funds.

Finance

Advice

Training

Prizes

Micro credits and other BBVA Innovation instruments Centre

Yo soy empleo

BBVA Open Talent

Micro credits and other Startup advice instruments

BBK Fundazioa

BBK Ideas competition

Diverse financial products

Entrepreneur advice

Gaztelanbidean

New business ideas competition

Caixa Capital Risk MicroBanck

Advice for different entrepreneur profiles

Entrepreneurship programmes

XXI Entrepreneur awards

Financial instruments

Specialized advice

Trainning Courses

Bstart up


5. Access to the most talented human capital Benefits of hiring talent A digital contents company can take advantage of tax benefits from employement. Public Institutions promote Training on the job

Subsidies for training and development of human capital 1M€ aids/year. 120 professionals/year.

30% of the gross salary (Up to € 9,000 per person). Up to 90.000€ subsidy per company when employing staff.

Enterprises paying Social Security generate a credit in order to invest in training for employees. Public Institutions also offer subsidised training programmes for Basque employees, including specific programmes in R&D&i. Up to € 20,000 on Human capital training and specialitation Up to € 30,000 /person for hiring senior R&D&I employees Up to € 20,000 /person for hiring junior R&D&I employees Through our subsidiary Bizkaia Talent, we attract foreign qualified personnel.

* In addition to all this bonus in Social Security Tax for researchers: 40% of the company¨s contribution for common contingenices


5. Access to the most talented human capital

UE

No work permit needed

Non UE

Work permit + Visa

Foreign Employees

Foreign Entrepreneurs

Job Offer

Company Registration

Residence and Work Permit

Residence and Work Permit

Visa

Visa 14/2013 Law for Entrepreneurs support and their interntionalization WHO: Investors Entrepreneurs Highly qualified professionals R&D&I development In company transfer

WHERE

(one-stop-shop): Residence authorisation: Strategic Collective UnitMinistery (resolution in 20 days) Visa: Spanish consulate country of origin (resolution in 10 days)

HOW: Passport or identity document (applicants must be over 18) Medical insurance accreditation document Criminal record certificate Economic means accreditation


6. International events related to biosciences economy

International events in Bilbao

Facilities to host international events


7. Public Advisory, all you need is us

Beaz S.A.U. is the company

Bilbao Ekintza is a

SPRI S.A. is the Business

of the Department of

Local Business Public

Development agency of the

Economic Promotion of

Entity (EPEL) created to

Autonomous Region of the

Biscay´s Provincial Council,

generate economic and

Basque Country, to promote

responsible for the

social wealth in the city,

the country as an attractive

development of innovative

enhancing its capabilities

place to invest in, and the

business projects and the

as a destination for

promotion of business

fostering of high growth

investment, business

dealings between foreign

startups, both local and

creation and growth,

and Basque companies.

foreign.

attracting visitors and talent.

For further information contact: foreignstartups@beaz.net


European Union European Regional Development Fund

Profile for Beaz

Bilbao Bizkaia Startup biosciences  

Land of opportunities for biosciences startup companies

Bilbao Bizkaia Startup biosciences  

Land of opportunities for biosciences startup companies

Profile for beaz
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