Current ANZUP trials
Testicular Cancer Testicular Cancer/Germ Cell* Tumours PHASE III Accelerated BEP Trial The current standard practice for the treatment of germ cell tumours is the use of the chemotherapy combination called BEP, which consists of three chemotherapy agents – Bleomycin, Etoposide and Cisplatin – administered on a three-weekly cycle. BEP is given with a drug called pegylated G-CSF (or pegfilgrastim) that stimulates white blood cell production. The purpose of this study is to determine whether giving the same dose of BEP on a two-weekly schedule will be more effective than a three-weekly schedule, and will be well tolerated. The two-weekly schedule is called “accelerated BEP” and the three-weekly schedule is called “standard BEP”. Up to 500 patients will be enrolled in the study in Australia, New Zealand and other countries. Currently we have 27 sites open in Australia and New Zealand, and 32 patients enrolled. We are also undergoing negotiations to set up the trial in Ireland with the support of Cancer Trials Ireland and the Medical Research Council, Cambridge University, UK.
• Macquarie Cancer Clinical Trials • Nepean Hospital • Prince of Wales Hospital • Royal North Shore Hospital • San Clinical Trials Unit • The Tweed Hospital • Westmead Hospital QLD • Princess Alexandra Hospital • Royal Brisbane & Women’s Hospital SA • Flinders Medical Centre • Royal Adelaide Hospital TAS • Royal Hobart Hospital
Please speak with your doctor if this is of interest to you or someone you know.
VIC
For more information, please go to the trials page on the ANZUP website: http://anzup.org.au/content. aspx?page=trials-testicular
• Box Hill Hospital
ANZUP collaborates with the University of Sydney through the National Health and Medical Research Council Clinical Trials Centre (NHMRC CTC).
• Sunshine Hospital
This ANZUP investigator initiated study is being funded by Cancer Australia
• Austin Health • Monash Medical Centre - Moorabin • Peter MacCallum Cancer Centre
WA • Fiona Stanley Hospital New Zealand
Current site locations for the P3BEP ANZUP clinical trial:
• Auckland Hospital
ACT
• Dunedin Hospital
• Canberra Hospital NSW • Border Medical Oncology • Calvary Mater Newcastle
• Christchurch Hospital • Palmerston North Hospital ANZUP has been awarded funding from the Sydney Catalyst Translational Cancer Research Centre for the Phase III Accelerated BEP translational sub-study. This will involve the collection of blood and tissue.
• Chris O’Brien Lifehouse • Concord Repatriation General Hospital
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