antibody)
• hepatitis B and may or may not still be infected with the virus • Does not signify immunity
7. IgM anti-HBc (by routine commercially available assays)
• Signifies recent contact with hepatitis B
8. HBV-DNA (by routine commercially available assays)
• Active viral replication • Ongoing liver disease • Patient infectious
Pasted from <http://www.comeunity.com/adoption/health/hepatitis/smith.html>
Glossary
Hepatitis B: Liver disease caused by the hepatitis B virus (HBV). HBV is found in the blood of infected persons and is commonly transmitted through unprotected sex. Hepatitis B Immune Globulin (HBIG): A product available for prophylaxis against hepatitis B virus infection. HBIG is prepared from plasma containing high titers of anti -HBs and provides short-term protection (three to six months). a. Hepatitis B Core Ag (HBcAg): A core protein antigen of the hepatitis B virus not readily detectable in serum. It is an indicator of replicating hepatitis B virus. b. Hepatitis B Core Antibody (anti-HBc): Antibody to the hepatitis core antigen. Appears at the onset of symptoms in acute hepatitis B and persists for life. The presence of anti-HBc indicates previous or ongoing infection with HBV. c. Hepatitis B e Ab (anti-HBe): Antibody to HBeAg that indicates good probability of long lasting viral clearance. d. Hepatitis B e Antigen (HBeAg): Secreted product of the nucleocapsid gene of HBV found in serum during acute and chronic hepatitis B. Its presence indicates the virus is replicating and the infected individual is potentially infectious. e. Hepatitis B Surface Antibody (anti-HBs): The presence of anti-HBs is generally interpreted as indicating recovery and immunity from HBV infection. f. Hepatitis B Surface Antigen (HBsAg): A serologic marker on the surface of HBV. It can be detected in high levels in serum during acute or chronic hepatitis. Pasted from <http://www.hepatitisbhelp.com/hepatitis_b_glossary.html>
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