23 minute read
Large Volume Treatment Plans Using the Merz Portfolio
Dr Euan Mackinnon explores if we can achieve surgical outcomes using a non-surgical approach
Advances in dermal filler properties and handling means we can achieve pleasing results for many of our patients with relatively small volumes of product. However, sometimes small volumes simply will not be able to produce the desired results that patient and practitioner may be wishing to achieve. In these cases, a frank and honest consultation with patients is required to avoid disappointment. I have long been fascinated by large volume treatment plans and in essence trying to effect surgical results for my patients using non-surgical modalities. In this case I will discuss my approach to a pan-facial treatment of a 30-year-old male using the Merz portfolio of dermal fillers. These fillers are my perfect armamentarium for pan-facial treatments. There truly is a product for every purpose that I require for my diverse range of patients. Naturally, when I inject higher volumes of products, I assume a higher level of risk both intra-operatively and post-procedurally. Therefore, it is imperative that I feel confident in the safety profile of my chosen injectables. I choose BELOTERO® as it has demonstrated a lower risk of inflammation compared to some other leading HA fillers whilst delivering exceptional results.4 Due to its ‘Cohesive Poly-densified Matrix (CPM)®’ technology, it offers the most homogeneous biointegration compared to other HA fillers and it really is a joy for me to inject due to its flowing qualities.4 The range allows for exceptional threedimensional tissue expansion whilst maintaining natural facial appearances both at rest and on animation.
Patient concerns Primary Concern: Retrognathic (retruded) mandible. Secondary Concerns: Tired appearance when not feeling tired. Flattening of the midface. Does not want to look overdone.
Treatment desires To have a stronger chin and jawline. To look more rested. To look more attractive.
Objective Upper Third – Temple hollowing. No static upper face lines. Middle Third – Deplete medial cheek fat pads with early evidence of malar split. Limited anterior cheek projection in profile. Limited zygomatic arch projection. Mild tear trough deformity. Lower Third – Class 2 skeletal base. Retrognathic (retruded) mandible and overjet of upper incisors. Poor definition of mandibular body and angle. Long philtrum, narrow horizontal dimension of upper lip and scope to balance vertical proportions of both lips. Surgical options This patient certainly could be treated with surgery in a combined maxillofacial and orthodontic approach to correct his skeletal discrepancies. This may include a Le Fort 1 maxillary osteotomy, bilateral sagittal split mandibular osteotomy +/- sliding genioplasty. Facial fat transfer or customised implants may also be considered. However, this would come at the price of extensive orthodontic treatment, surgical risks, and prolonged recovery time. In this case we decided to use dermal fillers to mimic the effects of surgery. 16.5ml of dermal filler was injected during one treatment session. Post-procedural pictures were taken at two weeks.
Treatment Scan the QR code to watch me perform this pan-facial treatment Temples: 2ml total. 1ml of BELOTERO® Volume1 per side using a supra-periosteal technique over two injection sites. Care is taken to identify the superficial temporal artery prior to injection. Cheeks: 2ml total. BELOTERO® Volume.1 Cannula entry point at the zygomatic prominence. Product fanned sub-SMAS into the deep cheek fat compartments indirectly providing support to the SOOF. Cannula flipped posteriorly through the same insertion point along the inferior aspect of the zygomatic arch to produce a masculine cheekbone vector. N.B. for female patients, follow the superior aspect of the arch towards the temple. Chin: 4ml total. BELOTERO® Volume.1 Dualplane technique. First, bone is simulated with supra-periosteal bolus placement to achieve better anterior projection and width. Secondly, a cannula is used subdermally to further enhance the anterior projection. Jawline: 7.5ml total of RADIESSE®.2 I use two cannula entry points for a full jawline augmentation allowing me to reach from the chin to the mandibular ramus. The
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Merz Aesthetics more distal entry point allows posterior augmentation of the angle and ramus. The more proximal entry point allows augmentation of the mandibular body, prejowl region and inferior aspect of the chin. My preferred jawline product for men is RADIESSE®.2 I primarily use this in the subdermal plane. The product is stiff on injection but can be easily moulded. The Calcium Hydroxyapatite technology is biostimulatory and produces robust and long-lasting definition through neocollagenesis. Clinicians need to be mindful of the short-lived (1-3 days) inflammatory response that occurs after injection of RADIESSE®2 and patients should be reassured and counselled on this pre-procedurally. This product is not hyaluronic acid based and should only be used by experienced injectors. Lips: 1ml total. BELOTERO® Balance.3 Sub-vermillion placement of product is my preference for men to allow for enhanced definition without creating an unnatural ledge at the lip border. The tubercles
were then enhanced based on clinical experience with superficial injection of Belotero®, no Tyndall effect has been observed.4 Summary 16.5ml of Merz Aesthetics dermal fillers were strategically injected in one treatment session. At two weeks there was full resolution of any minor post-procedural swelling or bruising, which is expected during a pan-facial treatment. Although there will always be a place for operative facial procedures, the exceptional advances in non-surgical alternatives can now mimic surgical outcomes without the surgical downtime and risk. Other benefits include the potential for a staged treatment approach and reversibility of HA products. Drawbacks of non-surgical options include the need for repeat treatments at intervals and the associated accumulative cost to the patients over time. This patient’s primary concern was his retrognathic mandible which has now been
vector. N.B. for female patients, follow the superior aspect of the arch towards the temple. Chin: 4ml total. BELOTERO® Volume1. Dual-plane technique. First, bone is simulated with supraperiosteal bolus placement to achieve better anterior projection and width. Secondly, a cannula is used sub-dermally to further enhance the anterior projection. Jawline: 7.5ml total of RADIESSE®2 . I use two cannula entry points for a full jawline augmentation allowing me to reach from the chin to the mandibular ramus. The more distal entry point allows posterior augmentation of the angle and ramus. The more proximal entry point allows augmentation of the adequately corrected. He appears more rested with a more masculine appearance. He has more three-dimensional structure to mandibular body, pre-jowl region his face without appearing over-filled. The and inferior aspect of the chin. exceptional integration of the Merz products My preferred jawline product for into the tissues enables the patient to men is RADIESSE®2. I primarily use express and emote in a completely natural this in the subdermal plane. The manner and he was thrilled with his results product is stiff on injection but can on review. be easily moulded. The Calcium Hydroxyapatite technology is biostimulatory and produces robust and long-lasting definition through neocollagenesis. Clinicians need to be mindful of the short-lived (1-3 days) inflammatory response that occurs after injection of RADIESSE®2 and patients should be reassured and counselled on this pre-procedurally. This product is not hyaluronic acid based and should only be used by experienced injectors. confidence
Lips: 1ml total. BELOTERO® Balance3. Sub-vermillion placement of product is my preference for men to allow for enhanced definition without creating an unnatural ledge at the lip border. The tubercles were then enhanced based on clinical experience with superficial injection of Belotero®, no Tyndall effect has been observed.4 Summary 16.5ml of Merz Aesthetics dermal fillers were strategically injected in one treatment session. At two weeks there was full resolution of any minor post-procedural swelling or bruising, which is expected during a pan-facial treatment. Although there will always be a place for operative facial procedures, the exceptional advances in non-surgical alternatives can now mimic surgical outcomes without the surgical downtime and risk. Other benefits include the potential for a staged treatment approach and reversibility of HA products. Drawbacks of non-surgical options include the need for repeat treatments at intervals and the associated accumulative cost to the patients over time. This patient’s primary concern was his retrognathic mandible which has now been adequately corrected. He appears more rested with a more masculine appearance. He has more three-dimensional structure to his face without appearing over-filled. The exceptional integration of the Merz products into the tissues enables the patient to express and emote in a completely natural manner and he was thrilled with his results on review.
Adverse events should be reported. Reporting forms and information for United Kingdom can be found at www.mhra.gov.uk/yellowcard. Reporting forms and information for Republic of Ireland can be found at https://www.hpra.ie/homepage/about-us/report-an-issue/mdiur. Adverse events should also be reported to Merz Pharma UK Ltd by email to UKdrugsafety@merz.com or on +44 (0) 333 200 4143. References: 1. BELOTERO® Volume 2. RADIESSE® 3. IFU BELOTERO® Balance Ref 4. Micheels, P., et al. (2012). „Superficial dermal injection of hyaluronic acid soft tissue fillers: comparative ultrasound study.“ Dermatol Surg 38(7 Pt 2): 1162-1169. @merzaesthetics.uki Merz Aesthetics UK & Ireland M-BEL-UKI-1282 Date of Preparation Otcober 2021
SCAN THE QR CODE TO WATCH THIS PAN-FACIAL TREATMENT TO REGISTER SCAN THE QR CODE OR VISIT merz-aesthetics.co.uk/events
vector. N.B. for female patients, follow the superior aspect of the arch towards the temple. Chin: 4ml total. BELOTERO® Volume1. Dual-plane technique. First, bone is simulated with supraperiosteal bolus placement to achieve better anterior projection and width. Secondly, a cannula is used sub-dermally to further enhance the anterior projection. Jawline: 7.5ml total of RADIESSE®2 . I use two cannula entry points for a full jawline augmentation allowing me to reach from the chin to the mandibular ramus. The more distal entry point allows posterior augmentation of the angle and ramus. The more proximal entry point allows augmentation of the mandibular body, pre-jowl region and inferior aspect of the chin. My preferred jawline product for men is RADIESSE®2. I primarily use this in the subdermal plane. The product is stiff on injection but can be easily moulded. The Calcium Hydroxyapatite technology is biostimulatory and produces robust and long-lasting definition through neocollagenesis. Clinicians need to be mindful of the short-lived (1-3 days) inflammatory response that occurs after injection of RADIESSE®2 and patients should be reassured and counselled on this pre-procedurally. This product is not hyaluronic acid based and should only be used by experienced injectors. WE BRING THE EXPERTS TO YOU. confidence
Lips: 1ml total. BELOTERO® Balance3. Sub-vermillion placement of product is my preference for men to allow for enhanced definition without creating an unnatural ledge at the lip border. The tubercles were then enhanced based on clinical experience with superficial injection of Belotero®, no Tyndall effect has been observed.4 Summary 16.5ml of Merz Aesthetics dermal fillers were strategically injected in one treatment session. At two weeks there was full resolution of any minor post-procedural swelling or bruising, which is expected during a pan-facial treatment. Although there will always be a place for operative facial procedures, the exceptional advances in non-surgical alternatives can now mimic surgical outcomes without the surgical downtime and risk. Other benefits include the potential for a staged treatment approach and reversibility of HA products. Drawbacks of non-surgical options include the need for repeat treatments at intervals and the associated accumulative cost to the patients over time. This patient’s primary concern was his retrognathic mandible which has now been adequately corrected. He appears more rested with a more masculine appearance. He has more three-dimensional structure to his face without appearing over-filled. The exceptional integration of the Merz products into the tissues enables the patient to express and emote in a completely natural manner and he was thrilled with his results on review.
Adverse events should be reported. Reporting forms and information for United Kingdom can be found at www.mhra.gov.uk/yellowcard. Reporting forms and information for Republic of Ireland can be found at https://www.hpra.ie/homepage/about-us/report-an-issue/mdiur. Adverse events should also be reported to Merz Pharma UK Ltd by email to UKdrugsafety@merz.com or on +44 (0) 333 200 4143. References: 1. BELOTERO® Volume 2. RADIESSE® 3. IFU BELOTERO® Balance Ref 4. Micheels, P., et al. (2012). „Superficial dermal injection of hyaluronic acid soft tissue fillers: comparative ultrasound study.“ Dermatol Surg 38(7 Pt 2): 1162-1169. @merzaesthetics.uki Merz Aesthetics UK & Ireland M-BEL-UKI-1282 Date of Preparation Otcober 2021
SCAN THE QR CODE TO WATCH THIS PAN-FACIAL TREATMENT TO REGISTER SCAN THE QR CODE OR VISIT merz-aesthetics.co.uk/events
vector. N.B. for female patients, follow the superior aspect of the arch towards the temple. Chin: 4ml total. BELOTERO® Volume1. Dual-plane technique. First, bone is simulated with supraperiosteal bolus placement to achieve better anterior projection and width. Secondly, a cannula is used sub-dermally to further enhance the anterior projection. Jawline: 7.5ml total of RADIESSE®2 . I use two cannula entry points for a full jawline augmentation allowing me to reach from the chin to the mandibular ramus. The more distal entry point allows posterior augmentation of the angle and ramus. The more proximal entry point allows augmentation of the mandibular body, pre-jowl region and inferior aspect of the chin. My preferred jawline product for men is RADIESSE®2. I primarily use this in the subdermal plane. The product is stiff on injection but can be easily moulded. The Calcium Hydroxyapatite technology is biostimulatory and produces robust and long-lasting definition through neocollagenesis. Clinicians need to be mindful of the short-lived (1-3 days) inflammatory response that occurs after injection of RADIESSE®2 and patients should be reassured and counselled on this pre-procedurally. This product is not hyaluronic acid based and should only be used by experienced injectors. WE BRING THE EXPERTS TO YOU. confidence
Lips: 1ml total. BELOTERO® Balance3. Sub-vermillion placement of product is my preference for men to allow for enhanced definition without creating an unnatural ledge at the lip border. The tubercles were then enhanced based on clinical experience with superficial injection of Belotero®, no Tyndall effect has been observed.4 Summary 16.5ml of Merz Aesthetics dermal fillers were strategically injected in one treatment session. At two weeks there was full resolution of any minor post-procedural swelling or bruising, which is expected during a pan-facial treatment. Although there will always be a place for operative facial procedures, the exceptional advances in non-surgical alternatives can now mimic surgical outcomes without the surgical downtime and risk. Other benefits include the potential for a staged treatment approach and reversibility of HA products. Drawbacks of non-surgical options include the need for repeat treatments at intervals and the associated accumulative cost to the patients over time. This patient’s primary concern was his retrognathic mandible which has now been adequately corrected. He appears more rested with a more masculine appearance. He has more three-dimensional structure to his face without appearing over-filled. The exceptional integration of the Merz products into the tissues enables the patient to express and emote in a completely natural manner and he was thrilled with his results on review.
Adverse events should be reported. Reporting forms and information for United Kingdom can be found at www.mhra.gov.uk/yellowcard. Reporting forms and information for Republic of Ireland can be found at https://www.hpra.ie/homepage/about-us/report-an-issue/mdiur. Adverse events should also be reported to Merz Pharma UK Ltd by email to UKdrugsafety@merz.com or on +44 (0) 333 200 4143. References: 1. BELOTERO® Volume 2. RADIESSE® 3. IFU BELOTERO® Balance Ref 4. Micheels, P., et al. (2012). „Superficial dermal injection of hyaluronic acid soft tissue fillers: comparative ultrasound study.“ Dermatol Surg 38(7 Pt 2): 1162-1169. @merzaesthetics.uki Merz Aesthetics UK & Ireland M-BEL-UKI-1282 Date of Preparation Otcober 2021
SCAN THE QR CODE TO WATCH THIS PAN-FACIAL TREATMENT TO REGISTER SCAN THE QR CODE OR VISIT merz-aesthetics.co.uk/events
Sub-vermillion placement oduct is my preference for men without creating an unnatural ledge at the lip border. The tubercles were experience with superficial injection fillers were strategically injected in one treatment session. At two weeks bruising, which is expected during a alternatives
WE BRING THE EXPERTS without the surgical downtime and TO YOU. gical options include the need for repeat associated accumulative cost to the This patient’s primary concern was
at the lip border. The tubercles were then enhanced based on clinical experience with superficial injection of Belotero®, no Tyndall effect has been observed.4 Summary 16.5ml of Merz Aesthetics dermal fillers were strategically injected in one treatment session. At two weeks there was full resolution of any minor post-procedural swelling or bruising, which is expected during a pan-facial treatment. Although there will always be a place for operative facial procedures, the exceptional advances in non-surgical alternatives can now mimic surgical outcomes without the surgical downtime and risk. Other benefits include the potential for a staged treatment approach and reversibility of HA products. Drawbacks of non-surgical options include the need for repeat treatments at intervals and the associated accumulative cost to the patients over time. SCAN THE SCAN THE This patient’s primary concern was QR CODE TO QR CODE TO his retrognathic mandible which has WATCH THIS WATCH THIS now been adequately corrected. He PAN-FACIAL PAN-FACIAL appears more rested with a more TREATMENT TREATMENT masculine appearance. He has more three-dimensional structure to his face without appearing over-filled.
The exceptional integration of The exceptional integration of the Merz products into the tissues the Merz products into the tissues
Belotero®, no Tyndall effect has been observed.4 Summary 16.5ml of Merz Aesthetics dermal fillers were strategically injected in one treatment session. At two weeks there was full resolution of any minor post-procedural swelling or bruising, which is expected during a pan-facial treatment. Although there will always be a place for operative facial procedures, the exceptional advances in non-surgical alternatives can now mimic surgical outcomes without the surgical downtime and risk. Other benefits include the SCAN THE potential for a staged treatment QR CODE TO approach and reversibility of HA WATCH THIS products. Drawbacks of non-surgical PAN-FACIAL options include the need for repeat TREATMENT treatments at intervals and the associated accumulative cost to the patients over time. The exceptional integration of This patient’s primary concern was the Merz products into the tissues his retrognathic mandible which has enables the patient to express now been adequately corrected. He and emote in a completely natural appears more rested with a more manner and he was thrilled with his masculine appearance. He has more results on review. three-dimensional structure to his face without appearing over-filled.
vector. N.B. for female patients, follow the superior aspect of the arch towards the temple. Chin: 4ml total. BELOTERO® Volume1. Dual-plane technique. First, bone is simulated with supraperiosteal bolus placement to achieve better anterior projection and width. Secondly, a cannula is used sub-dermally to further enhance the anterior projection. Jawline: 7.5ml total of RADIESSE®2 . I use two cannula entry points for a full jawline augmentation allowing me to reach from the chin to the mandibular ramus. The more distal entry point allows posterior augmentation of the angle and ramus. The more proximal entry point allows augmentation of the mandibular body, pre-jowl region and inferior aspect of the chin. My preferred jawline product for men is RADIESSE®2. I primarily use this in the subdermal plane. The product is stiff on injection but can be easily moulded. The Calcium Hydroxyapatite technology is biostimulatory and produces robust and long-lasting definition through neocollagenesis. Clinicians need to be mindful of the short-lived SCAN THE (1-3 days) inflammatory response QR CODE TO that occurs after injection of RADIESSE®2 and patients should WATCH THIS be reassured and counselled on PAN-FACIAL this pre-procedurally. This product is not hyaluronic acid based and TREATMENT should only be used by experienced injectors. The exceptional integration of the Merz products into the tissues enables the patient to express and emote in a completely natural manner and he was thrilled with his results on review. confidence
Lips: 1ml total. BELOTERO® Balance3. Sub-vermillion placement of product is my preference for men to allow for enhanced definition without creating an unnatural ledge at the lip border. The tubercles were then enhanced based on clinical experience with superficial injection of Belotero®, no Tyndall effect has been observed.4 Summary 16.5ml of Merz Aesthetics dermal fillers were strategically injected in one treatment session. At two weeks there was full resolution of any minor post-procedural swelling or bruising, which is expected during a pan-facial treatment. Although there will always be a place for operative facial procedures, the exceptional advances in non-surgical alternatives can now mimic surgical outcomes without the surgical downtime and risk. Other benefits include the potential for a staged treatment approach and reversibility of HA products. Drawbacks of non-surgical options include the need for repeat treatments at intervals and the associated accumulative cost to the patients over time. This patient’s primary concern was his retrognathic mandible which has now been adequately corrected. He appears more rested with a more masculine appearance. He has more three-dimensional structure to his face without appearing over-filled. The exceptional integration of the Merz products into the tissues enables the patient to express and emote in a completely natural manner and he was thrilled with his results on review.
Adverse events should be reported. Reporting forms and information for United Kingdom can be found at www.mhra.gov.uk/yellowcard. Reporting forms and information for Republic of Ireland can be found at https://www.hpra.ie/homepage/about-us/report-an-issue/mdiur. Adverse events should also be reported to Merz Pharma UK Ltd by email to UKdrugsafety@merz.com or on +44 (0) 333 200 4143. References: 1. BELOTERO® Volume 2. RADIESSE® 3. IFU BELOTERO® Balance Ref 4. Micheels, P., et al. (2012). „Superficial dermal injection of hyaluronic acid soft tissue fillers: comparative ultrasound study.“ Dermatol Surg 38(7 Pt 2): 1162-1169. @merzaesthetics.uki Merz Aesthetics UK & Ireland M-BEL-UKI-1282 Date of Preparation Otcober 2021
SCAN THE QR CODE TO WATCH THIS PAN-FACIAL TREATMENT TO REGISTER SCAN THE QR CODE OR VISIT merz-aesthetics.co.uk/events
WE BRING THE EXPERTS TO YOU.
Dr Euan Mackinnon is a dual qualified doctor and dentist. He is currently a Specialty Registrar in oral and maxillofacial surgery. His aesthetic practice is based at ‘The Lovely Clinic’ in Knightsbridge, London. Advances in dermal filler properties and handling means we can achieve pleasing results for many of our patients with relatively small volumes of product. However, sometimes small volumes simply will not be able to produce the desired results that patient and practitioner may be wishing to achieve. In these cases, a frank and honest consultation with patients is required to avoid disappointment. I have long been fascinated by large volume treatment plans and in essence trying to effect surgical results for my patients using nonsurgical modalities. In this case I will discuss my approach to a pan-facial treatment of a 30-year-old male using the Merz portfolio of dermal fillers. These fillers are my perfect armamentarium for pan-facial treatments. There truly is a product for every purpose that I require for my diverse range of patients. Naturally, when I inject higher volumes of products, I assume a higher level of risk both intra-operatively and post-procedurally. Therefore, it is imperative that I feel confident in the safety profile of my chosen injectables. I choose BELOTERO® as it has demonstrated a lower risk of inflammation compared to some other leading HA fillers whilst
compared to other HA fillers and it really is a joy for me to inject due to its flowing qualities. The range allows for exceptional three-dimensional tissue expansion whilst maintaining natural facial appearances both at rest and on animation. Patient concerns: Primary Concern: Retrognathic (retruded) mandible. Secondary Concerns: Tired appearance when not feeling tired. Flattening of the midface. Does not want to look overdone. Treatment desires: To have a stronger chin and jawline. To look more rested. To look more attractive. Objective Facial Assessment Upper Third – Temple hollowing. No static upper face lines. Middle Third – Deplete medial cheek fat pads with early evidence of malar split. Limited anterior cheek projection in profile. Limited zygomatic arch projection. Mild tear trough deformity. Lower Third – Class 2 skeletal base. Retrognathic (retruded) mandible and overjet of upper incisors. Poor definition of mandibular body and angle. Long philtrum, narrow
Dr Euan Mackinnon is a dual qualified Doctor and Dentist. He is currently a Specialty Registrar in Oral and Maxillofacial Surgery. His aesthetic practice is based at ‘The Lovely Clinic’ in Knightsbridge, London. Surgical Options This patient certainly could be treated with surgery in a combined Maxillofacial and Orthodontic approach to correct his skeletal discrepancies. This may include a Le Fort 1 maxillary osteotomy, bilateral sagittal split mandibular osteotomy +/- sliding genioplasty. Facial fat transfer or customised implants may also be considered. However, this would come at the price of extensive orthodontic treatment, surgical risks, and prolonged recovery time. In this case we decided to use dermal fillers to mimic the effects of surgery. 16.5ml of dermal filler was injected during one treatment session. Postprocedural pictures were taken at 2 weeks. Treatment Scan the QR code to watch me perform this pan-facial treatment Temples: 2ml total. 1ml of BELOTERO® Volume1 per side using a supra-periosteal technique over two injection sites. Care is taken to identify the superficial temporal artery prior to injection. Cheeks: 2ml total. BELOTERO® Volume1. Cannula entry point at the zygomatic prominence. Product fanned sub-SMAS into the deep cheek fat compartments indirectly providing support to the SOOF.
Before After Before After Patient before and after treatment LARGE VOLUME TREATMENT PLANS USING THE MERZ PORTFOLIO. vector. N.B. for female patients, follow the superior aspect of the CAN WE ACHIEVE SURGICAL OUTCOMES arch towards the temple. Chin: 4ml total. BELOTERO® USING A NON-SURGICAL APPROACH? Volume1. Dual-plane technique. First, bone is simulated with supra-BY EUAN MACKINNON periosteal bolus placement to achieve better anterior projection and width. Secondly, a cannula is used sub-dermally to further enhance the anterior projection. Jawline: 7.5ml total of RADIESSE® I use two cannula entry points for a full jawline augmentation allowing me to reach from the chin to the mandibular ramus. The more distal entry point allows posterior augmentation of the angle and ramus. The more proximal entry point allows augmentation of the mandibular body, pre-jowl region and inferior aspect of the chin. My preferred jawline product for men is RADIESSE®2. I primarily use this in the subdermal plane. The product is stiff on injection but can be easily moulded. The Calcium Hydroxyapatite technology is biostimulatory and produces robust and long-lasting definition through neocollagenesis. Clinicians need to be mindful of the short-lived (1-3 days) inflammatory response that occurs after injection of RADIESSE®2 and patients should be reassured and counselled on REFERENCES: 1. BELOTERO® Volume 2. RADIESSE® 3. IFU BELOTERO® Balance Ref 4. Micheels, P., et al. (2012). “Superficial dermal injection of hyaluronic acid soft tissue fillers: comparative ultrasound study.“ Dermatol Surg 38(7 Pt 2): 1162-1169. this pre-procedurally. This product is not hyaluronic acid based and should only be used by experienced injectors. M-BEL-UKI-1296 Date of Preparation October 2021 This advertorial is sponsored by Merz Aesthetics UK & Ireland TO REGISTER SCAN THE QR CODE OR VISIT merz-aesthetics.co.uk/events Adverse events should be reported. Reporting forms and information for United Kingdom can be found at www.mhra.gov.uk/yellowcard. Reporting forms and information for Republic of Ireland can be found at https://www.hpra.ie/homepage/about-us/report-an-issue/mdiur. Adverse events should also be reported to Merz Pharma UK Ltd by email to UKdrugsafety@merz.com or on +44 (0) 333 200 4143. References: 1. BELOTERO® Volume 2. RADIESSE® 3. IFU BELOTERO® Balance Ref 4. Micheels, P., et al. (2012). „Superficial dermal injection of hyaluronic acid soft tissue fillers: comparative ultrasound study.“ Dermatol Surg 38(7 Pt 2): 1162-1169.
