TEST BANK for Pharmacology for Health Professionals, 5th Ed by Bryant, B Knights, Darroch & Rowland

Bryant: Pharmacology for Health Professionals, 5th Edition Chapter 25: Drugs Affecting the Haemopoietic System Test Bank MULTIPLE CHOICE 1. A patient complains of lethargy and fatigue and is found to have low blood haemoglobin levels. The most appropriate drug therapy is: A. Vitamin K B. Filgrastim C. Iron D. None of the above ANS: C A condition in which there is a reduced oxygen-carrying capacity of the blood (due to reduced amount or functionality of haemoglobin) is referred to as anaemia and often manifests as fatigue. Iron deficiency anaemia is characterised by small red cells with reduced haemoglobin. Agents commonly used to treat this condition are the haematinics: folic acid, iron and vitamin B12.

2. Folic acid can be used to: A. Treat folate-deficiency anaemia B. Prevent neural tube defects in the growing fetus C. Prevent toxicity from methotrexate D. All of the above ANS: D Folic acid is essential for DNA synthesis, and dietary folic acid is reduced to tetrahydrofolate (FH4). Folic acid is used to treat folate-deficiency anaemia, to prevent neural tube defects in the growing fetus and to treat or prevent toxicity from the antimetabolite drug methotrexate.

3. Common adverse reactions associated with erythropoietin include: A. Hypertension B. Flu-like symptoms C. Peripheral oedema D. All of the above ANS: D Copyright © 2019 Elsevier Australia