AntiCancer Ravinder Singh Chawla
Introduction Anticancer, or antineoplastic, drugs are used to treat malignancies, or cancerous growths. Drug therapy may be used alone, or in combination with other treatments such as surgery or radiation therapy. ell Cycle Cell proliferation is involved in many physiological and pathological processes including growth, healing, repair, hypertrophy, hyperplasia and the development of tumours. Angiogenesis (the development of new blood vessels) necessarily occurs.
Several classes of drugs may be used in cancer treatment, depending on the nature of the organ involved. For example, breast cancers are commonly stimulated by estrogens, and may be treated with drugs that inactivate the sex hormones. Similarly, prostate cancer may be treated with drugs that inactivate androgens, the male sex hormone.
Treatment Anticancer therapy, especially in veterinary medicine, was based and still relies almost exclusively on surgical therapy, although associated therapy has developed over the past decades: surgery and/or chemotherapy and/or radiotherapy, with the development of cryotherapy, immunotherapy and in general, the adoption of techniques and methodologies used in human oncology. The therapeutic strategy should take into consideration three indispensable elements:
– the histological nature of the lesion; – the assessment of the extension of the tumor process; – the evaluation of the general disease state.
Medications
WHAT IS XTANDI ? Xtandi is categorized as an antiandrogen. Antiandrogens are substances that block the effects of testosterone. Cancer of the prostate depends on the male hormone testosterone or related androgens for its growth. If the amount of androgens are reduced it is possible to slow down or shrink the cancer. MEDICINE USES : Enzalutamide 40mg is used for the treatment of metastatic castration resistant prostate
cancer (prostate cancer that is resistant to medical or surgical treatments that lower testosterone). This medicine also prevents the androgens from working within the prostate cancer cells.
ZECYTE Abiraterone works by reducing androgen production in the body. Androgens are male hormones that can promote tumor growth in the prostate gland. ZECYTE medication is used along with prednisone to treat men with prostate cancer that has spread to other areas of the body and has not responded to surgical treatment that lowers testosterone levels. ZECYTE Tablets can cause foetal harm when administered to a pregnant woman. ZECYTE Tablets is not
indicated for use in women. ZECYTE Tablets is contraindicated in women who are or may become pregnant. If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, apprise the patient of the potential hazard to the foetus and the potential risk for pregnancy loss.
Erlonat (Erlotinib) is a kinase inhibitor which is primarily used to treat cell lung cancer, or pancreatic cancer when combined with a certain other medicine. It works by inhibiting growth to adjacent tissues in the body so that the cancerous cells slow down, allowing the patient a better environment to recover and fight the cancer naturally.
Uses: Erlonat 150mg tablet is used in the treatment of pancreatic cancer and
small cell lung cancer.Erlonat (Erlotinib) is a kinase inhibitor which is primarily used to treat cell lung cancer, or pancreatic cancer when combined with a certain other medicine.
Tasigna Nilotinib is a kinase inhibitor. It works by preventing the growth of cancer cells. It is mainly used for treating certain types of leukemia (eg, chronic myelogenous leukemia). All medicines may cause side effects, but many people have no, or minor, side effects. Consult with your doctor if any of these most common side effects persist or become bothersome: Rash, itching, nausea, vomiting, diarrhea, constipation
Tasigna prolongs the QT interval. Prior to Tasigna administration and periodically, monitor for hypokalemia or hypomagnesemia and correct deficienci