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LETTER FROM THE CHAIR

ANNUAL REPORT 2023 pediatrics.wisc.edu

THE YEAR IN PHOTOS

UW–Madison Diversity Forum features department members Department honors Dr. Ellen Wald’s time as chair with celebration and giving campaign On February 2, 2023, more than 300 people convened virtually and in person to honor Ellen Wald, MD, and her 17 years as chair of the Department of Pediatrics. A giving campaign established in Wald’s honor raised more than $100,000 for pediatric research. Wald continues to serve the department as a faculty member in the Division of Infectious Diseases, focusing on research and teaching.

The Diversity Forum is an all-campus and community opportunity to discuss, share, and learn about issues of equity, diversity, inclusion, and belonging. A group of experts from the Department of Pediatrics offered a breakout session during the 2022 event: “Health Equity Rounds: An Opportunity for Clinical and Anti-Racism Learning to Intersect.” Pictured left to right are Mary Ehlenbach, MD, associate professor and director of DEI; Mala Mathur, MD, MPH, associate professor and director of professional development; Laura Houser, MD, professor and director of advocacy; and Kelly McGregory, DO, associate professor and interim chief, Division of Child Protection.

Department members and local teens featured in AAP ‘Asking for a friend’ video series Story Slam offers platform for storytellers The inaugural Department of Pediatrics Story Slam took place on October 18, 2022, at Mystery to Me Bookstore. About 40 audience members listened as five storytellers — all connected to the department as faculty, residents, staff, or students — shared their stories on the evening’s theme, Second Chances.

The American Academy of Pediatrics (AAP) teamed up with the Department of Pediatrics Division of General Pediatrics and Adolescent Medicine and local teens for a YouTube video series about important mental health topics. In the “Asking for a friend” video series, department faculty members answered teens’ questions about self-harm, anxiety, and depression. Pictured here is Megan Yanny, MD, assistant professor.

University of Wisconsin Department of Pediatrics | Annual Report 2023

TABLE OF CONTENTS

Letter from the Interim Chair..................................4 Mission, Vision, and Values...................................... 5 Our People.................................................................6 Patient Care Highlights.......................................... 10 Education Highlights................................................14 Research Highlights.................................................18 Strategic Initiatives Highlights..............................24 Revenue and Expenses..........................................26 Publications..............................................................27

pediatrics.wisc.edu

LETTER FROM THE INTERIM CHAIR

t gives me great pleasure to share this 2023 Annual Report for the University of Wisconsin Department of Pediatrics. As the interim chair of the department, I have had the opportunity to see firsthand the excellence in our department across our clinical, research, and education work. We also leaned into community and advocacy work toward our larger mission to improve child health inside and outside our clinical spaces. One major event for us in fiscal year 2023 was the celebration of our previous department chair, Dr. Ellen Wald. We honored her time as chair during an event that brought together current and past department members, family and friends of Dr. Wald, and collaborators across our school and community to celebrate the growth and achievements that the past 16 years of her leadership have brought the department. We saw our strong clinical teams experience growth and increased demand in the past year, including expansion of specialty care telehealth consultations across the region, a new cardiology clinic at St. Vincent Hospital in Green Bay, and UNOS accreditation of our pediatric heart transplant program. Our primary care clinics saw a more than 14% increase in patient visits from last year, collaborated with the Department of Family Medicine and Community Health to offer a new Saturday sports physical clinic and weekday appointments that allowed providers to see an additional 300 high school students, and partnered with our psychiatry colleagues to develop a new learning opportunity for both groups to enhance their learning and skills in mental health issues for youth. Our pediatric cancer program was recognized in U.S. News & World Report as a top 50 program and is a program of distinction for American Family Children’s Hospital. Neonatology, pulmonology, and cardiology were also recognized. Our advanced practice providers (APPs) continue to be an integral part of our clinical care teams, providing exceptional continuity of care and learning opportunities within our subspecialty clinics and inpatient units. Last year our department was ranked 9th nationally in NIH-funded research among departments of pediatrics and saw its highest-ever total grants awarded: $55.86 million. As more conferences returned to being in-person events, many of our faculty members shared their research and collaborated with colleagues both nationally and internationally, attending more than 100 different pediatrics-related conferences throughout the year. In the spring, we had 47 faculty, staff, and trainees present at the multidisciplinary research meeting of Pediatric Academic Societies (PAS), one of the world’s largest gatherings of pediatricians. Within our department, we saw a new academic group form around qualitative research called Empowering Pediatricians Learning Qualitative Research (ExPLOR). This group reflects the growing interest in this research approach that centers on the voices of our patients, families, and providers. And we continued our tradition of Research Week, with the May 2023 event providing an outstanding lineup of talks from our residents and fellows, research updates from 17 faculty members, and the keynote address, “Cell Migration: From Patients to Zebrafish and Back.” A growing area of excellence in our academic work as a department is in quality improvement scholarship. In 2021, we introduced the Increasing Novel Scholarship through Peer Innovation, Research, and Education in Quality Improvement (INSPIRE-QI) cohort. Fiscal year 2023 saw its second INSPIRE-QI cohort and the introduction of INSPIRE-QI PRO, for more advanced QI training and mentorship. The breadth of the department’s QI work was on full display during the annual UW Health Kids Quality and Safety Poster Fair in September 2022, when

University of Wisconsin Department of Pediatrics | Annual Report 2023

MISSION, VISION & VALUES 33 department members presented their work in 14 different posters on topics from “Feasibility of Using Social Media to Provide Pediatric Pulmonary Patient Education” to “Improving Direct Breastfeeding at NICU Discharge.” Our training programs continue to be robust and strong. Last year, our new Pediatric Hospital Medicine Fellowship welcomed its first-ever fellow, our residency program introduced the Coaching to Optimize Resident Education (CORE) Mentor Program, and we hosted our inaugural Medical Education Week, which allowed faculty and staff members to focus in on learning and best practices in education. Our faculty members attend numerous community engagement events throughout the year. They provided family education at back-to-school events, supported local and national reading programs, and volunteered at local camps for children with specialized health needs. Last year the department was a premier sponsor of the American Family Children’s Hospital Gala, which helped raise $800,000 for pediatric research. The department also supported the Rainbow Project, a local organization that supports children and families who have experienced trauma, at its annual Rhumba 4 Rainbow fundraiser. And we sponsored the local chapter of Girls on the Run, which organizes programs that inspire girls to build confidence, kindness, and decision-making skills. In addition to running events, the group hosted a community-based Day of the Girl event and invited me to participate as a guest panelist. In addition to community-based engagement, our advocacy committee was involved in more targeted efforts to promote and enhance the health of children everywhere. Its members engaged in legislative advocacy as well as efforts to train the next generation of pediatricians in advocacy work and education. I am incredibly grateful for the work that our providers, learners, and staff contribute every day in our department. Please enjoy learning more about our work and how it emulates our mission, vision, and values in this 2023 Annual Report.

Megan Moreno Professor and Interim Chair

MISSION

VISION

The Department of Pediatrics promotes and enhances the health of children through outstanding clinical care, exemplary education of pediatric trainees, performance of cutting edge research, and vigorous advocacy.

Provision of the safest and highest quality, innovative and coordinated care in an environment that supports inquiry and discovery and promotes well-being and professionalism.

CORE VALUES Accountability Compassion Diversity Empathy Excellence Innovation Integrity Respect Teamwork

pediatrics.wisc.edu

OUR PEOPLE

The Department of Pediatrics is a vibrant academic department comprising more than 210 fac

BY THE NUMBERS

SELECTION OF AW

212

144

Faculty

Trainees

Academic & Research Staff

University Staff

American Diabetes Asso Young Investigator Awar Elizabeth Mann, MD, assis

Student Assistants & Hourlies

American Society of Ped Sharon Bartosh, MD, profe

Association of Public Hea Mei Wang Baker, MD, prof

Building Interdisciplinary Krisjon Olson, PhD, assista

Robert Wood Johnson Fo Medicine Elizabeth Cox, MD, PhD, p

FACULTY BY RANK

30%

38%

Assistant Professors Associate Professors Professors

32%

UW Health Clinical Docu CDI Team Award Tom Brazelton III, MD, MP

UW Health Physician Exc Jonathan Fliegel, MD, ass Award; Cathy Lee-Miller, M Transplant: Rising Star Clin General Pediatrics and Ado

UW Health Safety Leade Michael Wilhelm, MD, asso

UW SMPH Department o Matthew Harer, MD, assoc

UW SMPH Department o Emma Mohr, MD, PhD, ass

FACULTY BY TRACK

16% Clinical Health Sciences

28%

56%

Clinician Teacher Tenured/Tenure

University of Wisconsin Department of Pediatrics | Annual Report 2023

UW SMPH Group on Wom Interdisciplinary Researc Research Mentorship Aw Pelin Cengiz, MD, professo

Wisconsin Medical Alum Norman Fost, MD, MPH, p and Bioethics: Emeriti Facu Cardiology: Early Career Ac Oncology, and Bone Marro Jasmine Zapata, MD, MPH Distinguished Community S

culty in 16 subspecialty divisions.

WARDS AND HONORS

ociation (ADA) Diabetes in Youth Special Interest Group rd stant professor, Endocrinology and Diabetes

diatric Nephrology (ASPN) Outstanding Service Award essor and chief, Nephrology

alth Laboratories Everyday Life Saver Award in Newborn Screening fessor, Genetics and Metabolism

y Research Careers in Women’s Health (BIRCWH) Scholars Program ant professor, Cardiology

Foundation Health Policy Fellow at the National Academy of

professor, General Pediatrics and Adolescent Medicine

umentation Integrity (CDI) Department Superhero in Scrubs

PH, professor and vice chair of quality, Critical Care

cellence Awards sociate professor, Hospital Medicine and Complex Care: Clinical Educator MD, assistant professor, Hematology, Oncology, and Bone Marrow nical Educator Award; Emily Ruedinger, MD, MEd, associate professor, olescent Medicine: Rising Star Leadership Award

ership Award ociate professor, Critical Care

of Pediatrics Ellen R. Wald Award ciate professor, Neonatology and Newborn Nursery

of Pediatrics Gerard B. Odell Award sistant professor, Infectious Diseases

men in Medicine and Science (GWIMS)/UW Building ch Careers in Women’s Health (BIRCWH) Women’s Health ward or, Critical Care

mni Association Distinguished Medical Alumni Awards professor emeritus, Departments of Pediatrics and Medical History ulty Award – Clinical Science; Amy Peterson, MD, MS, professor, chievement Award; Paul Sondel, MD, PhD, professor, Hematology, ow Transplant: Resident Citation – Distinguished Resident Award; H, assistant professor, Neonatology and Newborn Nursery: Ralph Hawley Service Award

NATIONAL AND INTERNATIONAL SOCIETY MEMBERS Society for Pediatric Research David Allen, MD Awni Al-Subu, MD Jessica Babal, MD Mei Baker, MD Vivek Balasubramaniam, MD Heather Bartlett, MD Sabrina Butteris, MD Christian Capitini, MD Aaron Carrel, MD Pelin Cengiz, MD Ryan Coller, MD, MPH Elizabeth Cox, MD, PhD Rachel Engen, MD Philip Farrell, MD, PhD (emeritus) Peter Ferrazzano, MD Anthony Garcia-Prats, MD, PhD, MSc Bernadette Gillick, PhD, MSPT, PT Matthew Harer, MD Dinushan Kaluarachchi, MBBS Michelle Kelly, MD, PhD Kim Keppler-Noreuil, MD Pamela Kling, MD Janet Legare, MD Robert Lemanske, ME Hara Levy, MD, MMSc Ryan McAdams, MD Emma Mohr, MD, PhD Megan Moreno, MD, MSEd, MPH Amy Peterson, MD, MS J. Carter Ralphe, MD Michael Rock, MD Ellen Selkie, MD, MPH Kristin Shadman, MD Anne Marie Singh, MD Judith Smith, MD, PhD Nicholas Von Bergen, MD Ellen Wald, MD Bryn Webb, MD Sarah Webber, MD Michael Wilhelm, MD

American Pediatric Society David Allen, MD Heather Bartlett, MD Sharon Bartosh, MD James Conway, MD Kenneth DeSantes, MD Bruce Edmonson, MD, MPH (emeritus) Marlowe Eldridge, MD Philip Farrell, MD, PhD (emeritus) James Gern, MD Frank Greer, MD (emeritus) Kim Keppler-Noreiul, MD Bruce Klein, MD Michael MacDonald, MD (emeritus) Ryan McAdams, MD Stephen Meyn, MD, PhD Megan Moreno, MD, MSEd, MPH J. Carter Ralphe, MD Michael Rock, MD Paul Sondel, MD, PhD Ellen Wald, MD pediatrics.wisc.edu 7

OUR PEOPLE Our faculty has grown 42% over the last decade. In fiscal year 2023, we welcomed 17 new faculty members to the department.

FACULTY GROWTH 250

200

150

149

154

156

2014

2015

2016

164

175

176

2018

2019

193

201

208

212

100

0 2017

2020

2021

2022

2023

FACULTY PROMOTIONS Below is a list of faculty who were promoted in fiscal year 2023, their divisions, and their new ranks. Ryan Coller, MD, MPH Hospital Medicine and Complex Care Associate Professor

Matthew Harer, MD Neonatology and Newborn Nursery Associate Professor

Eileen Cowan, MD Neonatology and Newborn Nursery Associate Professor

Laura Houser, MD General Pediatrics and Adolescent Medicine Professor

Patricia Deffner-Valley, MD General Pediatrics and Adolescent Medicine Associate Professor

Dinushan Kaluarachchi, MBBS Neonatology and Newborn Nursery Associate Professor

University of Wisconsin Department of Pediatrics | Annual Report 2023

NEW FACULTY Below is a list of new faculty who started during fiscal year 2023 and their divisions. Luke Addesso, MD General Pediatrics and Adolescent Medicine Christina Amend, MD Hematology, Oncology, and Bone Marrow Transplant Timothy Elgin, DO Neonatology and Newborn Nursery Taylor House, MD Nephrology Whitley Hulse, MD Neonatology and Newborn Nursery Dana Irrer, MD Cardiology

Amanda Jackson, MD General Pediatrics and Adolescent Medicine Child Protection

Rebecca Richards, MD, PhD Hematology, Oncology, and Bone Marrow Transplant

Kelsey Legro, DO General Pediatrics and Adolescent Medicine Sarah Mc Dermott, MBS, DO Hematology, Oncology, and Bone Marrow Transplant Neil Munjal, MD, MS Critical Care Claire O’Leary, PhD Allergy, Immunology, and Rheumatology Douglas Olk, MD General Pediatrics and Adolescent Medicine

Suhaib Kazmouz, MD, MSc Cardiology Associate Professor Troy Kleist, MD General Pediatrics and Adolescent Medicine Associate Professor Nina Menda, MD Neonatology and Newborn Nursery Associate Professor

Nicholas Pytel, DO Hematology, Oncology, and Bone Marrow Transplant

Margaret Scandura, MD General Pediatrics and Adolescent Medicine Jo Wilson, MD Allergy, Immunology, and Rheumatology Jonathan Wong, DO Gastroenterology, Hepatology, and Nutrition Global Pediatrics

Diane Puccetti, MD Hematology, Oncology, and Bone Marrow Transplant Professor Sarah Webber, MD Hospital Medicine and Complex Care Associate Professor

pediatrics.wisc.edu

PATIENT CARE HIGHLIGHTS PATIENT VISITS In fiscal year 2023, the combined number of general pediatrics, specialty, and outreach patient clinic visits totaled 120,860.

1% General Pediatrics, All Locations

36%

Specialty Visits

63%

Outreach Visits Source: Qlikview Ambulatory Encounters Report by Fiscal Year pulled as of 10/19/23 Note: Does not include outreach visits performed in non-UW Health owned sites

American Family Children’s Hospital in Madison, Wisconsin.

University of Wisconsin Department of Pediatrics | Annual Report 2023

PATIENT CARE HIGHLIGHTS OUR CLINICAL SITES AMERICAN FAMILY CHILDREN’S HOSPITAL American Family Children’s Hospital (AFCH) in Madison, Wisconsin, offers children the most advanced and specialized medical care in a healing environment designed especially for pediatric patients and their families. AFCH is a Level 1 Trauma Center and has a Level IV NICU. WAISMAN CENTER The Waisman Center provides comprehensive clinical services and support to individuals with disabilities and their families through 11 interdisciplinary specialty clinics that operate in collaboration with UW Health and several UW–Madison academic departments. UNITYPOINT HEALTH-MERITER This 448-bed community hospital in Madison, Wisconsin, partners with our faculty and UW Health Kids to offer extraordinary maternal, fetal, and neonatal care for families and babies. The Center for Perinatal Care, the Level III NICU, and the Birthing Center are staffed by an advanced team of experts from our Division of Neonatology and Newborn Nursery. SSM HEALTH ST. MARY’S HOSPITAL At this 440-bed tertiary referral hospital in Madison, Wisconsin, faculty from our Division of Hospital Medicine provide consultative services to pediatric and adolescent patients. REGIONAL & OUTREACH CLINICS Our faculty provide a full range of outpatient clinical services at 11 clinic locations in Madison and surrounding communities. They also provide regional specialty outreach services (onsite and remote) in 31 cities in Wisconsin and Illinois.

The Waisman Center at the University of Wisconsin–Madison.

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PATIENT CARE HIGHLIGHTS The Department of Pediatrics provides exceptional patient care to children in Wisconsin and beyond. Our faculty members were involved in planning and launching innovative programs and clinics in fiscal year 2023.

Members of the Kids Heart Transplant Program team. Front row, left to right: Krisjon Olson, PhD, research; Katie Fleiner, RN, transplant coordinator; Josh Hermsen, MD, surgical director; Sonya Kirmani, MD, medical director; Bridget Lucas, NP, transplant nurse practitioner. Back row, left to right: Sarah Mandli, RD; Megan Fecht, supervisor, social work; Heather Jaeger, RN, program manager; Charlie Bergstrom, MD, pediatric cardiac critical care director; Kathleen (Kai) Gorenc, NP, transplant nurse practitioner.

UW Health Transplant Center Launches pediatric heart transplant program In June 2023, UW Health announced a new pediatric heart transplant program at American Family Children’s Hospital. The new program makes the UW Health Transplant Center one of only six centers in the nation — and the only one in the Midwest — transplanting five major organs in adults and kids. The congenital heart program at UW Health Kids is recognized nationally for providing outstanding care for even the most complex forms of congenital heart disease. Sonya Kirmani, MD, assistant professor, Division of Cardiology, serves as medical director of the new pediatric heart transplant program. She said offering transplantation locally expands pediatric cardiology services and directly benefits patients and families, allowing them to be able to remain in Madison for the full spectrum of potential care needs. Previously, about six to eight children every year would need to travel out of the region for a heart transplant. “It’s a big burden on families,” Kirmani said. “A heart transplant means life-long care. Families have had to relocate and find new jobs to accommodate the transplant. Now we can provide for all our patients’ needs more locally.”

Read more remarkable stories from 2023. Visit pediatrics.wisc.edu and uwhealth.org/news Follow us on social media

University of Wisconsin Department of Pediatrics | Annual Report 2023

@WiscPediatrics & @WiscPedsRes @UWHealthKids & @WiscPedsRes

PATIENT CARE HIGHLIGHTS

Department members reflect on Fetal Diagnosis and Treatment Center one year after opening

New clinic focuses on treatment of teens and young adults with substance use disorders In May 2023, Kathryn Gannon-Loew, MD, MS, assistant professor, Division of General Pediatrics and Adolescent Medicine, saw her first day in a new clinic dedicated to the treatment of teens and young adults with substance use disorders.

Chemotherapy technique places American Family Children’s Hospital at the forefront of retinoblastoma treatment in the Midwest In August 2022, two University of Wisconsin Department of Pediatrics clinicians were part of a team that introduced a new chemotherapy technique at American Family Children’s Hospital to treat a patient with retinoblastoma, the most common type of eye cancer in children. Margo Hoover-Regan, MD, associate professor, Division of Hematology, Oncology, and Bone Marrow Transplant, and Shawn Damodharan, DO, hematology and oncology fellow, employed intraarterial chemotherapy (IAC) to deliver anti-tumor drugs directly to the tumor bud in the retina.

The Fetal Diagnosis and Treatment Center opened in March 2022. It works in tandem with the Center for Perinatal Care, a joint program between UW Health and UnityPoint Health– Meriter Hospital, where it is located. The center depends upon the work and expertise of clinicians and staff in several clinical programs, including the Department of Pediatrics. After more than one busy year of saving babies through innovative diagnosis and often through in utero intervention, members of the Department of Pediatrics shared their perceptions on the center’s staff and work. Rachel Engen, MD, assistant professor, Division of Nephrology, discussed how learning early about an abnormal fetal kidney condition through early diagnosis at the center gives parents time to form and ask questions and prepare for the child’s care after delivery. “This makes the first days after birth much smoother so we can quickly provide effective care,” Engen said. Medical director of the Level IV NICU at American Family Children’s Hospital, Jamie Limjoco, MD, MS, MMM, associate professor, Division of Neonatology and Newborn Nursery, noted that the NICU is much busier since the Fetal Diagnosis and Treatment Center opened. “Babies who have had fetal surgery are often born early with unique needs,” Limjoco explained. “They can now stay locally rather than having to travel, and this significantly changes the lives of the families since these babies typically have a long NICU stay.” She praised the center’s dedication to collaboration and noted that its strong and inclusive communications strategies have been essential to successful results.

pediatrics.wisc.edu

EDUCATION HIGHLIGHTS Our educational programs meet the needs of learners at all levels: undergraduates, medical students, residents, fellows, postgraduate trainees, and practicing health care professionals. Graduating residents enter desirable primary care practices or leading fellowship programs in academic medical centers. Fellows excel as subspecialty clinicians, researchers, and leaders in academic pediatrics. Education by the Numbers

FELLOWS

FELLOWSHIP PROGRAMS

RESIDENTS

RESIDENCY PATHWAYS

GRAND ROUNDS

NAMED LECTURES

SIGNATURE CONFERENCES

RESIDENCY HIGHLIGHTS Seven of the 15 graduates of our 2023 residency program entered subspecialty fellowships, two became chief residents, five were appointed to faculty positions within our department, and one entered clinical practice outside of the UW.

14% 7% 33%

Fellowship

46%

UW Pediatrics Faculty Chief Resident Non-UW Clinical Practice

CORE Mentor Program welcomes inaugural members Last year, the Department of Pediatrics Residency Program welcomed the inaugural members of its Coaching to Optimize Resident Education (CORE) Mentor Program. CORE mentors bring experience from general pediatrics, specialty care, hospital medicine, and global health, through early-, mid-, and late-career contexts, all with a passion for mentorship and coaching. CORE mentors work with the program in resident curriculum, clinical coaching, mentorship, assessment, and recruitment. The mentors include the following people: • Ellen Connor, MD, professor, Division of Endocrinology and Diabetes • Jonathan Fliegel, MD, associate professor, Division of Hospital Medicine and Complex Care • Kathleen Kastner, MD, assistant professor, Division of Developmental Pediatrics and Rehabilitation Medicine • Danielle Rodgers, MD, assistant professor, Division of General Pediatrics and Adolescent Medicine • Carolyn Sleeth, MD, MPH, assistant professor, Division of General Pediatrics and Adolescent Medicine • Nicole St. Clair, MD, associate professor, Divisions of Hospital Medicine and Complex Care and Global Pediatrics • Megan Yanny, MD, assistant professor, Division of General Pediatrics and Adolescent Medicine

University of Wisconsin Department of Pediatrics | Annual Report 2023

RESIDENCY PROGRAM EXCELLENCE AWARDS The following faculty, residents, and fellows were the recipients of the Pediatric Residency program’s 2023 Teaching and Patient Care Excellence Awards. The awards were presented at the resident graduation ceremony. Charles C. Lobeck Medical Education Award for Outstanding Teaching in Pediatrics Kathleen Maginot, MD, associate professor, Division of Cardiology Ellen R. Wald Intellectual Curiosity in Medicine Award Melissa Cercone, MD, associate professor, Division of Critical Care Outstanding General Pediatrician Troy Kleist, MD, associate professor, Division of General Pediatrics and Adolescent Medicine Todd Varness Outstanding Clinical Teaching Award Laura Chen, MD, assistant professor, Division of Hospital Medicine and Complex Care

Outstanding Fellow Zachary Gray, MD, Division of Critical Care Jan Brady Award for Outstanding Second Year Resident Abbie Whitman, MD Outstanding Clerkship Teaching by a Pediatric Resident Samantha Tyler, DO Outstanding Senior Resident Hannah Schumacher, MD Resident Research Award Therese Woodring, MD Outstanding Pediatric Intern Carlee Blakemore, MD

DEPARTMENT OF PEDIATRICS RESEARCH AND DEVELOPMENT AWARDS

The Department of Pediatrics grants two rounds of department-funded Research and Development (R&D) Awards each year. The following is a list of residents and clinical fellows who received R&D Awards in support of research activities, including quality improvement projects, in the 2023 academic year. Kelsi Alexander, DO, resident, PGY3, “Incidence and Outcomes of Vesicoureteral Reflux on Pediatric Renal Transplant” Najla Ba Sharahil, MD, pulmonology fellow, “Sleep Disordered Breathing among Young Children with Trisomy 21: A Retrospective Review of Sleep Study Data” Daniel Murphy, MD, resident, PGY2, “Healthy Parks, Healthy Communities” Joseph Presson, DO, hematology and oncology fellow, “Barriers to Utilizing Palliative Care in Care of Pediatric and Young Adult Patients with Sickle Cell Disease: A Qualitative Study” Morteza Seifi, PhD, laboratory genetics and genomics fellow, “Investigating the Relationship Between GATA2 Mutations and Chromosomal Instability in Myelodysplastic Syndrome and Acute Myeloid Leukemia” Tyler Sternhagen, MD, resident, PGY3, “Improving Pediatric Resident Trauma Resuscitation Attendance, Comfort, and Competencies through Standardized Curriculum Development” Bryan Vonasek, MD, pediatric infectious diseases fellow, “Neglected Tropical Enteric Diseases in Malawian Children Hospitalized with Severe Acute Malnutrition”

EDUCATION HIGHLIGHTS

Last year, more than 650 students were enrolled in the University of Wisconsin School of Medicine and Public Health Doctor of Medicine program. About 175 of the department’s faculty members are involved in their training.

Medical education leaders guide medical students through a comprehensive pediatrics learning experience Four dedicated medical education leaders in the Department of Pediatrics guide medical students successfully through the pediatrics Phase 1 block for medical students and the clinical rounds in Phases 2 and 3 of the School of Medicine and Public Health’s four-year three-phase ForWard Curriculum. Kirstin Nackers, MD, is director of pediatric undergraduate medical education, helping support pediatrics throughout the four years of the curriculum. She is also the integrated block leader for the required Phase 2 course, Care Across the Life Cycle, in which students rotate through the general and subspecialty pediatric divisions. “For many students, learning how to interact with both the pediatric patient and their care giver is a daunting task,” Nackers said, “and they are so appreciative of the guidance and mentorship they receive when they rotate through our department.” Dominic Co, MD, PhD, is assistant director of pediatric undergraduate medical education, and assistant block leader for Care Across the Life Cycle. He works with others to craft the content for Phase 2 students’ core pediatric experiences. “I am passionate about teaching medical students in particular,” Co said. “As a pediatrician, I understand the importance of early intervention in childhood health to promote lifelong health — I guess that has carried over into my intervening early in medical education as well.”

Eileen Cowan, MD, is the integrated block leader for the Phase 1 course, Human Family Tree, responsible for diverse content from genetics and embryology to oncology and aging issues. As pediatric pre-clerkship director, she integrates pediatric content into the preclinical portion of the ForWard Curriculum to foster student interest in pediatrics. “I think our enthusiasm for pediatrics shines through,” Cowan said. “We model excellence in best practices, teamwork, respect, and compassion that allows medical students to experience pediatrics in an outstanding environment.” Kathleen Kastner, MD, is assistant block leader for the Phase 1 course, Human Family Tree. She is the director for the developmental pediatrics rotation, in which Phase 2 and 3 students rotate through the specialty. As director for the Phase 3 public health elective, she oversees students in the Wisconsin Leadership Education in Neurodevelopmental & Related Disabilities (LEND) program. “All physicians will care for people with disabilities,” Kastner noted, “so it is essential that students learn about disability advocacy and understand their unique health care needs.”

University of Wisconsin Department of Pediatrics | Annual Report 2023

EDUCATION HIGHLIGHTS FELLOWSHIP HIGHLIGHTS Eight people graduated from our fellowship programs last year. Four entered clinical practice outside of our department, one was appointed to a faculty position at the UW, two accepted positions in industry laboratories, and one pursued additional subspecialty fellowship training.

Non-UW Clinical Practice UW Pediatrics Faculty Industry laboratories The faculty members above are listed clockwise from the top left. Kirstin Nackers, MD, is associate professor in the Division of Hospital Medicine and Complex Care Dominic Co, MD, PhD, is associate professor in the Division of Allergy, Immunology, and Rheumatology Eileen Cowan, MD, is associate professor in the Division of Neonatology and Newborn Nursery Kathleen Kastner, MD, is assistant professor in the Division of Developmental Pediatrics and Rehabilitation Medicine

Continued training

New fellowship program welcomes its first trainee In July 2022, the new Pediatric Hospital Medicine Fellowship welcomed its first-ever fellow. Haroon Ali, MD, trained at the University of Illinois College of Medicine at Peoria, where he completed pediatric residency, chief residency, simulation fellowship, and two years as a pediatric hospitalist. His research interests include medical education, pediatric sedation, medical simulation, and quality improvement. As a fellow, Haroon is helping to produce a simulation curriculum to train new fellows on taking interhospital transfer calls and is conducting research on the necessity of fentanyl use in deep sedation for pediatric lumbar punctures.

Research Week Fellow Excellence in Research Award During the 2023 Department of Pediatrics Research Week, Shawn Damodharan, DO, fellow in the Hematology and Oncology Fellowship, was chosen for the Fellow Excellence in Research Award for his presentation, “Diffuse Midline Glioma Multiomics Characterization.”

pediatrics.wisc.edu

RESEARCH HIGHLIGHTS Research funding for the Department of Pediatrics reached a new high in fiscal year 2023. The total amount of awards increased by more than 7% over the previous year. Total Grant Funding by Division

Summary of Research Projects and Awards

Awarded July 1, 2022 — June 30, 2023

Hematology, Oncology & Bone Marrow Transplant $5,986,760

$55.86M TOTAL AMOUNT OF AWARDS

$36.6M

FUNDING FROM THE NIH

172

RESEARCH PROJECTS WITH OUR FACULTY AS PI

51%

OF RESEARCH PROJECTS WERE CLINICAL STUDIES

NEW AWARDS GRANTED TO INVESTIGATORS

Infectious Diseases $5,636,538

Allergy, Immunology & Rheumatology $28,610,257

Neonatology & Newborn Nursery $3,705,285 Genetics & Metabolism $3,627,621

General Pediatrics & Adolescent Medicine $3,546,127 Cardiology $1,315,216

Gastroenterology, Hepatology & Nutrition $1,500

Hospital Medicine & Complex Care $1,252,309 Developmental Pediatrics & Rehabilitation Medicine $599,250

Nephrology $35,389 Endocrinology & Diabetes $543,780

Pulmonology & Sleep Medicine $445,897

Critical Care $552,337

University of Wisconsin Department of Pediatrics | Annual Report 2023

RESEARCH HIGHLIGHTS

Department ranks 9th nationally in NIH funding The Department of Pediatrics continues to be a leader among pediatric departments in federal research funding from the National Institutes of Health (NIH). The department ranked No. 9 in NIH research funding among medical school pediatric departments in the Blue Ridge Institute for Medical Research 2022 rankings. It was the second year in a row that the department ranked in the Top 10 and the department’s fourth Top 10 ranking in six years.

A SELECTION OF NATIONAL INSTITUTES OF HEALTH (NIH) AWARDS Healthy Brain and Child Development National Consortium The University of Wisconsin-Madison will be one of 25 sites to study early brain and behavior development and the impact of early exposure to substances – such as opioids – and social stressors in infants and young children. The Healthy Brain and Child Development National Consortium will follow 7,500 mothers and their children from across the U.S. from before birth to 10 years of age to better understand which harmful and protective environments exert the greatest impact on child development. The Wisconsin site will be led by Douglas Dean III, PhD, assistant professor, Division of Neonatology and Newborn Nursery, and Julie Poehlmann-Tynan, PhD, Dorothy O’Brien Professor of Human Ecology. Modulation of the Biliary Immune Niche by the Microbiome The biliary system is the network of organs and vessels that make, store, and transfer bile through the body. Biliary tract disease and inflammation represent an enormous human health burden and are leading causes of liver failure. Claire O’Leary, PhD, assistant professor, Division of Allergy, Immunology, and Rheumatology, will test how the microbiome can impact the biliary system’s immune network and how this impacts tissue function during inflammation. This work will also assess how the microbiome influences immunity and inflammation in other regions of the gastrointestinal tract, such as the small intestine. A longitudinal study investigating TDM and adolescent health and development: Brain, Behavior and Well-Being Researchers at the University of Wisconsin are studying how technology and digital media (TDM) influence health behaviors and well-being in adolescents, with an emphasis on both positive and negative impacts of social media. The study will take place over two years, observing the social media use of 400 adolescents ages 13-15 from the state of Wisconsin. Researchers will gather data on participants through surveys, interviews, functional magnetic resonance imaging (fMRI) scans, and Ecological Momentary Assessments (EMA), which are questions participants can answer via text message to get in-the-moment health screening information. Megan Moreno, MD, MSEd, MPH, professor and interim chair, Division of General Pediatrics and Adolescent Medicine, is the study’s principal investigator. Co-PIs are Ellen Selkie, MD, MPH, assistant professor, Division of General Pediatrics and Adolescent Medicine, and Chris Cascio, PhD, assistant professor, UW School of Journalism and Mass Communication.

pediatrics.wisc.edu

RESEARCH HIGHLIGHTS The Department of Pediatrics was awarded more than $55.86 million in grant funding in fiscal year 2023, an increase of 161% since 2014 and 368% over the last 20 years. TOTAL RESEARCH FUNDING By Source, Fiscal Years 2014 to 2023 $60,000,000 $55,000,000 $50,000,000 $45,000,000 $40,000,000 $35,000,000 $30,000,000 $25,000,000 $20,000,000 $15,000,000 $10,000,000 $5,000,000 $0

2014 NIH

2015

2016

Federal/State

2017

2018

2019

Internal Grants and Gifts

University of Wisconsin Department of Pediatrics | Annual Report 2023

2020 Industry

2021

2022

Foundation/O

RESEARCH HIGHLIGHTS A SELECTION OF OTHER AWARDS Simulation-based Microaggressions Training for Residents and Faculty A research team led by two members of the Department of Pediatrics received one of the inaugural Catalyst Awards for Transformation in Graduate Medical Education from the Josiah Macy Jr. Foundation. Emily Ruedinger, MD, MEd, associate professor, Division of General Pediatrics and Adolescent Medicine, and Sushant Srinivasan, MD, MHPE, associate professor in the Division of Critical Care, will use their $50,000 grant to use simulation to teach residents and faculty to quickly recognize and respond to microaggressions in clinical situations. Chasing Expedited and Equitable Treatment Access for Children (CHEETA) Unitaid and the World Health Organization awarded Anthony Garcia-Prats, MD, PhD, MSc, associate professor, Divisions of General Pediatrics and Adolescent Medicine and Global Pediatrics, a seven-month grant for $50,000 that will support startup funding for the project “Chasing Expedited and Equitable Treatment Access for Children (CHEETA).” The overall goal of the CHEETA project is to advocate for the accelerated development of and equitable access to new TB drugs for children. NOT-gated CAR T cells to overcome on-target, off-tumor toxicity in AML The American Society of Hematology (ASH) awarded Rebecca Richards, MD, PhD, assistant professor, Division of Hematology, Oncology, and Bone Marrow Transplant, an ASH Fellow Scholar Award of $100,000. Richards’ research is in chimeric antigen receptor (CAR) T cell therapy as it applies to patients with acute myeloid leukemia (AML). She is using this funding, combined with both National Institutes of Health and departmental research support, to develop next-generation CAR T cells that are less likely to cause the complication known as ontarget, off-tumor toxicity that causes the CAR T cells to attack healthy, non-cancerous tissue. Develop and characterize a mouse model for WARS2 The Texas-based non-profit organization Elijah’s Project for Hope awarded Bryn Webb, MD, associate professor, Division of Genetics and Metabolism, a two-year research grant in the amount of $282,553 to investigate a rare genetic disorder that results from mutations in the WARS2 gene. The neurological disease caused by WARS2 gene mutations is known to manifest early in life, typically in the first year, and causes profound global developmental delay, lack of control of body movement (ataxia), and tremors. The goal of the research project is to develop three transgenic mouse lines that contain different WARS2 mutations present in patients with differing disease severity, which will be instrumental in testing possible new therapies.

2023

Other

Ann Allen receives AAP grant to improve discharge planning processes for infants with NOWS and their birth parents Ann Allen, MD, associate professor, Division of Hospital Medicine and Complex Care, was awarded a Maternal–Infant Health and Opioid Use Virtual Learning Collaborative grant from the American Academy of Pediatrics (AAP) for her work at SSM Health St. Mary’s Hospital. This program focuses on improving the discharge planning processes to ensure a safe transition from hospital to home and support continuity care through referrals to community-based providers. Through a blended learning experience, pediatric hospital teams can improve the discharge planning processes for infants with neonatal opioid withdrawal syndrome (NOWS) and their birth parents.

pediatrics.wisc.edu

RESEARCH HIGHLIGHTS

Left: A child enjoys a kid-sized vehicle during a Cars Curing Kids event. Below: Scenes from Cars Curing Kids events in recent years.

Cars Curing Kids grants support Department of Pediatrics researchers Established in 2014 in honor of a little girl, McKenah, who succumbed at age three to Short Bowel Syndrome and untreatable liver failure, Cars Curing Kids has a clear mission. It is committed to funding and supporting causes that improve health outcomes in the lives of children in southern Wisconsin. Its founder and board chairman, Peter Nichols, MD, PhD, is associate professor in the Department of Surgery, and a surgeon in the American Family Children Hospital. He initially treated McKenah. In Cars Curing Kids, he works with a group of car collectors and enthusiasts who are passionate about children’s health care. Cars Curing Kids raises funds through automotive events that share the group’s love and enthusiasm for cars with children and adults. The group hosts between four and eight events each year, many of them car shows and all organized by volunteers. Funds raised through the events are directed to combating childhood diseases and other health care challenges. Supporting health care research for timely and effective results for kids is the group’s goal. Cars Curing Kids aims to grant the money it raises within 18 months of receiving the donations, and its grantees pledge to use the funds for projects that provide impact within one to three years. Fundraising efforts are dedicated to supporting local causes and grant funding. Cars Curing Kids raises about $70,000 each year and awards anywhere from two to eight grants annually. It has funded programs for bike helmets, car safety seats, EMS pediatric specialty equipment, and many grants to researchers working on projects that support improved infant health. Last year, it funded four Department of Pediatrics-initiated projects. (See sidebar, next page.)

University of Wisconsin Department of Pediatrics | Annual Report 2023

RESEARCH HIGHLIGHTS

Faculty Research and Development Awards The Department of Pediatrics grants two rounds of departmentfunded Research and Development (R&D) Awards each year. The following is a list of faculty members who received R&D Awards in support of research activities, including quality improvement projects, in the 2023 academic year.

Cars Curing Kids awarded grants to four department-initiated projects last year Cathy Lee-Miller, MD, assistant professor, Division of Hematology, Oncology, and Bone Marrow Transplant, received a $30,458, five-year grant for a pilot study of modified therapy for NCI standard risk B-cell acute lymphoblastic leukemia (ALL). Dinushan Kaluarachchi, MBBS, associate professor, Division of Neonatology and Newborn Nursery, received a $6,273 grant to improve treatment for preterm infants with respiratory distress syndrome. Laura Chen, MD, assistant professor, Division of Hospital Medicine and Complex Care, received a $4,000 grant to help align local care practices at the American Family Children’s Hospital with those of national experts in hyperbilirubinemia treatment. Ann O’Kane, RN, a pediatric trach coordinator at UW Health who works closely with the Division of Pulmonology and Sleep Medicine, received a $5,000 grant to support parents and caregivers of children with tracheostomies.

Doug Dean III, PhD, assistant professor, Division of Neonatology and Newborn Nursery, “Examination of Brain Structure and Language Development in Infants with Down Syndrome” Heidi Kloster, MD, associate professor, Division of Hospital Medicine and Complex Care, “Caregiver Stories: Families of Children with Medical Complexity Navigate the Intersection of Health Care, Parenting, and Advocacy” Amy Peterson, MD, MS, professor, Division of Cardiology, “Universal Pediatric Cholesterol Screening to Identify Familial Hypercholesterolemia: Insight into Differences in Practices and Barriers via an International Survey J. Carter Ralphe, MD, professor and chief, Division of Cardiology, “Leveraging CRISPR Modified Human iPS Cells to Probe Genotype Specificity in Hypertrophic Cardiomyopathy” Xiangqiang Shao, PhD, MS, assistant professor, Division of Genetics and Metabolism, “Molecular Testing for Polygenic Hypercholesterolemia in Pediatric Patients Clinically Diagnosed with Familial Hypercholesterolemia (FH) but Negative for Monogenic FH” Judith Smith, MD, PhD, associate professor, Division of Allergy, Immunology, and Rheumatology, “Investigating UPR-immune Links in Infectious Spondyloarthritis” Sarah Webber, MD, associate professor, Division of Hospital Medicine and Complex Care, “A Pilot Study to Investigate the Feasibility of Collaborative Workflow Transformation Intervention” Brian Williams, MD, assistant professor, Division of Hospital Medicine and Complex Care, “Treating Nicotine Addiction in Caregivers of Children at American Family Children’s Hospital”

pediatrics.wisc.edu

STRATEGIC INITIATIVES HIGHLIGHTS

Five department-wide directorships focus on broad initiatives relevant across the department The directors develop, initiate, and oversee strategic improvements and programming in five a professional development; diversity, equity, and inclusion (DEI); quality improvement scholars

Professional Development and Advocacy Inaugural Murray Katcher Child Health Advocacy Lecture Last year, the Department of Pediatrics introduced its newest lectureship: the Murray Katcher Child Health Advocacy Lectureship. Murray Katcher, MD, PhD, emeritus professor of pediatrics, served the department for 35 years as a clinician and safety advocate. Katcher’s advocacy work has been legendary and transformative. One example is his decade-long effort to regulate hot water heater settings, which eventually changed the industry. The Murray Katcher Child Health Advocacy Lectureship is intended to promote the depth of concern and engaged dedication to change that improves safety that characterizes Katcher’s work. Katcher presented the inaugural lecture, “My Journey as a Health Advocate,” on April 13, 2023.

In the photo: Dr. Murray Katcher at the inaugural Murray Katcher Child Health Advocacy Lecture.

Advocacy

Department hos

Department membe Family Children’s Hos coordinated by Direc committee’s health p Division of Neonatolo associate professor, D Director of Governm with pediatric leaders

Diversity, Equi Inclusion and Professional D

Health Equity Ro Quality Improvement Scholarship INSPIRE-QI INSPIRE-QI invites early- and early mid-career faculty members and fellows to develop quality improvement (QI) skills through a mentored scholarly project. An advanced program, INSPIRE-QI Pro, builds upon the INSPIRE-QI curriculum and challenges participants to disseminate their scholarly QI projects through supported writing. Last year, INSPIRE-QI and INSPIRE-QI Pro met monthly over the course of nine months with their five-member cohorts and engaged QI-interested colleges during special sessions.

University of Wisconsin Department of Pediatrics | Annual Report 2023

Health Equity Round case-based conferen curriculum built on th education has the po health equity. Inspire program introduced Center in 2016, our d Health Equity Round department is comm Health Equity Round

STRATEGIC INITIATIVES HIGHLIGHTS OUR DIRECTORS

t’s 16 divisions. areas: advocacy; ship; and well-being.

sts Wisconsin legislators in talks about child health

ers hosted nine Wisconsin government leaders for tours of American spital during three days in February and March. The tours were ctor of Advocacy Laura Houser, MD, and hosted by the advocacy policy co-leads, Nathan Lepp, MD, MPH, associate professor, ogy and Newborn Nursery, and Vivek Balasubramaniam, MD, Division of Pulmonology and Sleep Medicine, along with UW Health ment Relations Connie Schulze. The groups visited various units, met ship and therapy dogs, and discussed children’s health.

ity, and

Development

ounds

ds is a longitudinal, nce series and he belief that medical ower to improve ed by a similar at Boston Medical department launched ds in fall 2021. The mitted to offering two ds each year.

Director of Advocacy Laura Houser, MD, professor, Divisions of General Pediatrics and Adolescent Medicine and Global Pediatrics Director of Professional Development Mala Mathur, MD, MPH, associate professor, Division of General Pediatrics and Adolescent Medicine

Well-being How We Work In January 2023, the department launched How We Work, a year-long initiative to introduce department members to workflows, tools, and resources they can use to facilitate a work culture that empowers people to engage in productive, efficient, meaningful, and collaborative work. How We Work includes regular technology training sessions, department-wide monthly time-blocking for deep work, and the development of a gathering guide to help department members make informed decisions and utilize best practices when conducting and attending gatherings.

Director of Diversity, Equity, and Inclusion (DEI) Mary Ehlenbach, MD, associate professor, Division of Hospital Medicine and Complex Care

Director of Quality Improvement Scholarship Kristin Shadman, MD, professor, Division of Hospital Medicine and Complex Care

Director of Well-being Sarah Webber, MD, associate professor, Division of Hospital Medicine and Complex Care

pediatrics.wisc.edu

REVENUE & EXPENSES In fiscal year 2023, our department earned more than $133.5 million in total revenue.

REVENUE

Research Grants Clinical Revenue Clinical Funding Support Short-Term Funding MAMA and State Funding Other Revenue (Outreach and Legal) Indirect Cost Recovery

EXPENSES Physician Compensation Research Expenses Staff Compensation APP Compensation Resident Compensation Fellow Compensation Other Operating Expenses Purchased Services Professional Business Allowance Education Program Information Technology

University of Wisconsin Department of Pediatrics | Annual Report 2023

PUBLICATIONS In fiscal year 2023, our faculty published 272 papers in peer-reviewed journals. You can view a list of citations in the following pages. If you would like to access one of the articles, please use the provided links or search for it on pubmed.gov using the PMID number located at the end of most citations.

PUBLICATIONS

pediatrics.wisc.edu

PUBLICATIONS

Al-Subu AM, Adams CK, Dykstra SA, Langkamp MR, Yngsdal-Krenz RA, Al Subu RM, Zhang Z, Baker KN, Brazelton TB. Management of Critically Ill Patients With Spinal Muscular Atrophy Admitted With Acute Respiratory Failure. Respir Care. 2023 Jan 3:respcare.10353. doi: 10.4187/respcare.10353. Epub ahead of print. PMID: 36596652.

Al-Subu AM, Friestrom E, Terry E, Langkamp MR, Adams CK, Yngsdal-Krenz RA, Lasarev MR, DeSanti RL, Vanderloo JP, Bogenschutz MC. Effectiveness and Safety of Albuterol Solutions with and without Benzalkonium Chloride. Respir Care. 2023 Jan 20:respcare.10747. doi: 10.4187/respcare.10747. Epub ahead of print. PMID: 36669780.

Alankarage D, Enriquez A, Steiner RD, Raggio C, Higgins M, Milnes D, Humphreys DT, Duncan EL, Sparrow DB, Giampietro PF, Chapman G, Dunwoodie SL. Myhre syndrome is caused by dominant-negative dysregulation of SMAD4 and other co-factors. Differentiation. 2022 Nov-Dec;128:1-12. doi: 10.1016/j. diff.2022.09.002. Epub 2022 Sep 24. PMID: 36194927.

Allen BJ, Stratman ZE, Kerr BR, Zhao Q, Moreno MA. Associations Between Psychosocial Measures and Digital Media Use Among Transgender Youth: Crosssectional Study. JMIR Pediatr Parent. 2021 Aug 13;4(3):e25801. doi: 10.2196/25801. PMID: 34398792; PMCID: PMC8398741.

Allen CC, Anagnostopoulos PV. Commentary: Obstruction or No Obstruction? That Is the Question. Is CT the Answer We’ve Been Searching for?. Semin Thorac Cardiovasc Surg. 2023 Spring;35(1):138-139. doi: 10.1053/j. semtcvs.2022.03.006. Epub 2022 Mar 21. PMID: 35331897.

Allen CC, Canada K, Schlueter S, Zhang X, Bartlett H. Gabapentin Can Improve Irritability and Feeding Tolerance in Single Ventricle Interstage Patients: A Case Series. Pediatr Cardiol. 2023 Feb;44(2):487-493. doi: 10.1007/ s00246-022-03009-5. Epub 2022 Sep 21. PMID: 36131139.

Allen CC, Swanson BL, Zhang X, Schnapp B, Ruhland SM, Bartlett HL. Optimizing efficiency of a custom clinical decision support tool improves adult congenital heart disease care. American Heart Journal Plus: Cardiology Research and Practice. https://doi.org/10.1016/j. ahjo.2023.100303.

Altman MC, Kattan M, O’Connor GT, Murphy RC, Whalen E, LeBeau P, Calatroni A, Gill MA, Gruchalla RS, Liu AH, Lovinsky-Desir S, Pongracic JA, Kercsmar CM, Khurana Hershey GK, Zoratti EM, Teach SJ, Bacharier LB, Wheatley LM, Sigelman SM, Gergen PJ, Togias A, Busse WW, Gern JE, Jackson DJ; National Institute of Allergy and Infectious Disease’s Inner City Asthma Consortium. Associations between outdoor air pollutants and non-viral asthma exacerbations and airway inflammatory responses in children and adolescents living in urban areas in the USA: a retrospective secondary analysis. Lancet Planet Health. 2023 Jan;7(1):e33-e44. doi: 10.1016/S25425196(22)00302-3. PMID: 36608946.

Anderson J, Majzner RG, Sondel PM. Immunotherapy of Neuroblastoma: Facts and Hopes. Clin Cancer Res. 2022 Aug 2;28(15):3196-3206. doi: 10.1158/1078-0432. CCR-21-1356. PMID: 35435953; PMCID: PMC9344822.

10.

Ansar A, Livett T, Beaton W, Carrel AL, Bekx MT. Sharp Rise in New-Onset Pediatric Diabetes During the COVID-19 Pandemic. WMJ. 2022 Oct;121(3):177-180. PMID: 36301642.

University of Wisconsin Department of Pediatrics | Annual Report 2023

PUBLICATIONS

11.

12.

13.

Aris IM, Perng W, Dabelea D, Padula AM, Alshawabkeh A, Vélez-Vega CM, Aschner JL, Camargo CA Jr, Sussman TJ, Dunlop AL, Elliott AJ, Ferrara A, Zhu Y, Joseph CLM, Singh AM, Hartert T, Cacho F, Karagas MR, North-Reid T, Lester BM, Kelly NR, Ganiban JM, Chu SH, O’Connor TG, Fry RC, Norman G, Trasande L, Restrepo B, James P, Oken E; Program Collaborators for Environmental Influences on Child Health Outcomes. Associations of Neighborhood Opportunity and Social Vulnerability With Trajectories of Childhood Body Mass Index and Obesity Among US Children. JAMA Netw Open. 2022 Dec 1;5(12):e2247957. doi: 10.1001/ jamanetworkopen.2022.47957. PMID: 36547983. Asgharzadeh S, Marachelian A, Villablanca JG, Liu WY, Kennedy R, Sposto R, Naranjo A, Tenney S, Yu AL, Ozkaynak MF, Sondel PM, Park JR, Seeger RC. Expression of neuroblastoma-related genes in bone marrow at end of high-risk neuroblastoma therapy. Pediatr Blood Cancer. 2022 Sep;69(9):e29719. doi: 10.1002/pbc.29719. Epub 2022 Apr 20. PMID: 35441784; PMCID: PMC9329214. Aufhauser Jr DD, Condit P, Schmit KM, Conway JH, Cook S, D’Alessandro AM, Furuya KN. (2023). Liver Transplantation for Refractory Congenital Cytomegaloviral Hepatitis. JPGN Reports, 4(1), e275.

14.

Bacharier LB, Jackson DJ. Biologics in the treatment of asthma in children and adolescents. J Allergy Clin Immunol. 2023 Jan 24:S0091-6749(23)00006-4. doi: 10.1016/j. jaci.2023.01.002. Epub ahead of print. PMID: 36702649.

15.

Baker RM, Tiedt K, Rushton J, Ciccarelli M. “Nuts and Bolts: Promote Understanding of Learning Styles in Self-Study.” Acad Pediatr. 2023 Jun 16;. doi: 10.1016/j. acap.2023.06.017. [Epub ahead of print] PMID: 37331469.

16.

Ballout RA, Livinski A, Fu YP, Steiner RD, Remaley AT. Statins for Smith-Lemli-Opitz syndrome. Cochrane Database Syst Rev. 2022 Nov 14;11(11):CD013521. doi: 10.1002/14651858. CD013521.pub2. PMID: 36373961; PMCID: PMC9661876.

17.

Barth M, Xavier AC, Armenian S, Audino AN, Blazin L, Bloom D, Chung J, Davies K, Ding H, Ford JB, GalardyPJ, Hanna R, Hayashi R, Lee-Miller C, Machnitz AJ, Maloney KW, Marks L, Martin PL, McCall D, Pacheco M, Reilly AF, Roshal M, Song S, Weinstein J, Zarnegar-Lumley S, McMillian N, Schonfeld R, Sundar H. Pediatric Aggressive Mature B-Cell Lymphomas, Version 3.2022, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2022 Nov;20(11):1267-1275. doi: 10.6004/jnccn.2022.0057. PMID: 36351334.

18.

Barton HJ, Pflaster E, Loganathar S, Werner A, Tarfa A, Wilkins D, Ehlenbach ML, Katz B, Coller RJ, Valdez R, Werner NE. What makes a home? Designing home personas to represent the homes of families caring for children with medical complexity. Appl Ergon. 2022 Sep 16;106:103900.doi: 10.1016/j. apergo.2022.103900. Epub ahead of print. PMID: 36122551.

19.

Basnet S, Mohanty C, Bochkov YA, Brockman-Schneider RA, Kendziorski C, Gern JE. Rhinovirus C Causes Heterogeneous Infection and Gene Expression in Airway Epithelial Cell Subsets. Mucosal Immunol. 2023 Feb 14:S1933-0219(23)00009-0. doi: 10.1016/j. mucimm.2023.01.008. Epub ahead of print. PMID: 36796588.

pediatrics.wisc.edu

PUBLICATIONS

20.

Bekelman TA, Trasande L, Law A, Blackwell CK, Jacobson LP, Bastain TM, Breton CV, Elliott AJ, Ferrara A, Karagas MR, Aschner JL, Bornkamp N, Camargo CA Jr, Comstock SS, Dunlop AL, Ganiban JM, Gern JE, Karr CJ, Kelly RS, Lyall K, O’Shea TM, Schweitzer JB, LeWinn KZ. Opportunities for understanding the COVID-19 pandemic and child health in the United States: the Environmental influences on Child Health Outcomes (ECHO) program. Front Pediatr. 2023 Jun 15;11:1171214. doi: 10.3389/ fped.2023.1171214. PMID: 37397146; PMCID: PMC10308998.

25.

Boriosi JP, Eickhoff JC, Bryndzia C, Peters M, Hollman GA. An exploratory study of distractions during the induction phase of pediatric procedural sedation with propofol. Paediatr Anaesth. 2023 Feb 23. doi: 10.1111/ pan.14649. Epub ahead of print. PMID: 36815455.

26.

Boriosi JP, Lasarev ML, Ferrazano PA, Peters ME. The Nature, Frequency, and Timing of Pediatric Sedation Adverse Events. Hosp Pediatr. 2022 Nov 1;12(11):930-936. doi: 10.1542/hpeds.2022-006531. PMID: 36254629.

21.

Beverley KM, Pattnaik BR. Inward rectifier potassium (Kir) channels in the retina: living our vision. Am J Physiol Cell Physiol. 2022 Sep 1;323(3):C772-C782. doi: 10.1152/ ajpcell.00112.2022. Epub 2022 Aug 1. PMID: 35912989; PMCID: PMC9448332.

27.

Brar KK, Singh AM, De Guzman N, Aquino M. Atopic Dermatitis: Diagnosis, Disparity, and Management in Children of Color. NASN Sch Nurse. 2023 Mar;38(2):56-61. doi: 10.1177/1942602X221147033. Epub 2023 Jan 23. PMID: 36688411.

22.

Bikson M, Ganho-Ávila A, Datta A, Gillick B, Joensson MG, Kim S, Kim J, Kirton A, Lee K, Marjenin T, Onarheim B, Rehn EM, Sack AT, Unal G. Limited output transcranial electrical stimulation 2023 (LOTES-2023): Updates on engineering principles, regulatory statutes, and industry standards for wellness, over-thecounter, or prescription devices with low risk. Brain Stimul. 2023 May 16;16(3):840-853. doi: 10.1016/j.brs.2023.05.008. Epub ahead of print. PMID: 37201865.

28.

Brichta C, Hoppe KK, Lasarev MR, Harer MW. The effect of antenatal indomethacin on extremely preterm neonatal kidney function. J Matern Fetal Neonatal Med. 2022 Dec;35(25):4870-4877. doi: 10.1080/14767058.2020.1869933. Epub 2021 Jan 5. PMID: 33402005.

29.

Brichta CE, Godwin J, Norlin S, Kling PJ. Impact and interactions between risk factors on the iron status of at-risk neonates. J Perinatol. 2022 Aug;42(8):1103-1109. doi: 10.1038/s41372022-01318-4. Epub 2022 Feb 7. PMID: 35132153.

23.

24.

Binger K, Kerr BR, Lewis MA, Fairlie AM, Hyzer RH, Moreno MA. Cannabis Use Among Female Community College Students Who Use Alcohol in a State With and a State Without Nonmedical Cannabis Legalization in the US. WMJ. 2023 May;122(2):95-100. PMID: 37141471. Birn RM, Dean DC 3rd, Wooten W, Planalp EM, Kecskemeti S, Alexander AL, Goldsmith HH, Davidson RJ. Reduction of Motion Artifacts in Functional Connectivity Resulting from Infrequent Large Motion. Brain Connect. 2022 Oct;12(8):740-753. doi: 10.1089/ brain.2021.0133. Epub 2022 Apr 11. PMID: 35152725; PMCID: PMC9618388.

30. Broder MS, Adams DM, Canaud G, Collins C, Davis K, Frieden IJ, Gibbs SN, Hammill AM, Keppler-Noreuil KM, Nakano TA, Penington A, Srivastava S, Tollefson MM, Warman ML. RAND/UCLA Modified Delphi Panel on the Severity, Testing, and Medical Management of PIK3CA-Related Spectrum Disorders (PROS). Journal of Vascular Anomalies 4(2):p e067, June 2023. | DOI: 10.1097/ JOVA.0000000000000067

University of Wisconsin Department of Pediatrics | Annual Report 2023

PUBLICATIONS

31.

Brown DH, Zhang X, Al-Subu AM, Von Bergen NH. Improvements in Accuracy and Confidence in Rhythm Identification After Cardiac Surgery Using the AtriAmp Signals. J Intensive Care Med. 2023 Mar 20:8850666231164613. doi: 10.1177/08850666231164613. Epub ahead of print. PMID: 36938624.

32.

Brown JE, Aldred B, Boulter T, Sullivan R, Ver Hoeve J, Pattnaik BR, Schmitt M. A case report of retinal dystrophy in patients with PACS1 syndrome. Ophthalmic Genet. 2023 May 23;:1-5. doi: 10.1080/13816810.2023.2216272. [Epub ahead of print] PMID: 37218682.

33.

Bryan MA, Evans YN, Gower A, Moreno MA. Does Exposure to Pediatrician or Parent Blog Content Influence Infant Safe Sleep Practices? Matern Child Health J. 2023 Feb;27(2):251-261. doi: 10.1007/s10995-022-03579-z. Epub 2023 Jan 5. PMID: 36604380.

34.

Carlson PM, Patel RB, Birstler J, Rodriquez M, Sun C, Erbe AK, Bates AM, Marsh I, Grudzinski J, Hernandez R, Pieper AA, Feils AS, Rakhmilevich AL, Weichert JP, Bednarz BP, Sondel PM, Morris ZS. Radiation to all macroscopic sites of tumor permits greater systemic antitumor response to in situ vaccination. J Immunother Cancer. 2023 Jan;11(1):e005463. doi: 10.1136/jitc2022-005463. PMID: 36639155; PMCID: PMC9843201.

35.

Carter KJ, Ward AT, Kellawan JM, Harrell JW, Peltonen GL, Roberts GS, Al-Subu A, Hagen SA, Serlin RC, Eldridge M, Wieben O, Schrage WG. Reduced basal macrovascular and microvascular cerebral blood flow in young adults with metabolic syndrome: potential mechanisms. J Appl Physiol (1985). 2023 May 18. doi: 10.1152/japplphysiol.00688.2022. Epub ahead of print. PMID: 37199780.

36.

Case NT, Berman J, Blehert DS, Cramer RA, Cuomo C, Currie CR, Ene IV, Fisher MC, FritzLaylin LK, Gerstein AC, Glass NL, Gow NAR, Gurr SJ, Hittinger CT, Hohl TM, Iliev ID, James TY, Jin H, Klein BS, Kronstad JW, Lorch JM, McGovern V, Mitchell AP, Segre JA, Shapiro RS, Sheppard DC, Sil A, Stajich JE, Stukenbrock EE, Taylor JW, Thompson D, Wright GD, Heitman J, Cowen LE. The future of fungi: threats and opportunities. G3 (Bethesda). 2022 Nov 4;12(11). doi: 10.1093/g3journal/jkac224. PMID: 36179219; PMCID: PMC9635647.

37.

Cederbaum SD, Edwards J, Kellmeyer T, Peters Y, Steiner RD. Taste-masked formulation of sodium phenylbutyrate (ACER-001) for the treatment of urea cycle disorders. Mol Genet Metab. 2023 Apr;138(4):107558. doi: 10.1016/j. ymgme.2023.107558. Epub 2023 Mar 8. PMID: 37004302.

38.

Chandran A, Burjak M, Petimar J, Hamra G, Melough MM, Dunlop AL, Snyder BM, Litonjua AA, Hartert T, Gern JE, Alshawabkeh AN, Aschner J, Camargo CA Jr, Dabelea D, Duarte CS, Ferrara A, Ganiban JM, Gilliland F, Gold DR, Hedderson M, Herbstman JB, Hockett C, Karagas MR, Kerver JM, Lee-Sarwar KA, Lester B, McEvoy CT, Niu Z, Stanford JB, Wright R, Zimmerman E, Farzan S, Zhang Z, Knapp E. Changes in Body Mass Index Among SchoolAged Youths Following Implementation of the Healthy, Hunger-Free Kids Act of 2010. JAMA Pediatr. 2023 Feb 13:e225828. doi: 10.1001/ jamapediatrics.2022.5828. Epub ahead of print. PMID: 36780186; PMCID: PMC9926355.

39.

Chen LP, Gerber DM, Coller RJ. Admitting what is needed: How the health system and society can reduce hospitalizations for children with medical complexity. J Hosp Med. 2022 Aug 23;. doi: 10.1002/jhm.12948.[Epub ahead of print] PMID: 35996947.

pediatrics.wisc.edu

PUBLICATIONS

40. Cheng EM, Tsarovsky NW, Sondel PM, Rakhmilevich AL. Interleukin-12 as an in situ cancer vaccine component: a review. Cancer Immunol Immunother. 2022 Sep;71(9):20572065. doi: 10.1007/s00262-022-03144-1. Epub 2022 Jan 13. Review. PMID: 35024897; PMCID: PMC9276836.

45.

41.

Ching AS, Zhang X, Furuya KN, Benoy ME, Bartlett HL. Turner syndrome may be associated with hepatic adenoma. Am J Med Genet A. 2023 Oct;191(10):2578-2584. doi: 10.1002/ajmg.a.63341. Epub 2023 Jul 10. PMID: 37431210.

42.

Chmielewski J, Chaudhry PM, Harer MW, Menon S, South AM, Chappell A, Griffin R, Askenazi D, Jetton J, Starr MC; Neonatal Kidney Collaborative. Documentation of acute kidney injury at discharge from the neonatal intensive care unit and role of nephrology consultation. J Perinatol. 2022 Jul;42(7):930936. doi: 10.1038/s41372-022-01424-3. Epub 2022 Jun 8. PMID: 35676535; PMCID: PMC9280854.

46. Coller RJ, Kelly MM, Howell KD, Warner G, Butteris SM, Ehlenbach ML, Werner N, Katz B, McBride JA, Kieren M, Koval S, DeMuri GP. In-Home COVID-19 Testing for Children with Medical Complexity: Feasibility and Association With School Attendance and Safety Perceptions. Am J Public Health. 2022 Sep 15;:e1-e5.doi: 10.2105/AJPH.2022.306971. Epub ahead of print. PMID: 36108256.

43.

Cho MM, Song L, Quamine AE, Szewc F, Shi L, Erbe AK, Ebben JD, Turicek DP, Kline JM, Lafeber EO, Phillips MF, Ceas AS, Capitini CM. CD155 blockade enhances allogeneic natural killer cell-mediated antitumor response against osteosarcoma. bioRxiv. 2023 Jun 20;. doi: 10.1101/2023.06.07.544144. PMID: 37333207; PMCID: PMC10274782.

44. Chongsuwat T, Ibrahim AO, Evensen AE, Conway JH, Zwick M, Oloya W. Health facility assessments of cervical cancer prevention, early diagnosis, and treatment services in Gulu, Uganda. PLOS Glob Public Health. 2023 Feb 15;3(2):e0000785. doi: 10.1371/journal. pgph.0000785. PMID: 36962762; PMCID: PMC10021907.

Claes DJ, Richardson T, Harer MW, Keswani M, Neu A, Mahon ACR, Somers MJ, Traum AZ, Warady BA. Survival of neonates born with kidney failure during the initial hospitalization. Pediatr Nephrol. 2023 Feb;38(2):583-591. doi: 10.1007/s00467-022-05626-x. Epub 2022 Jun 2. PMID: 35655038.

47.

Corkery AT, Miller KB, Loeper CA, Tetri LH, Pearson AG, Loggie NA, Howery AJ, Eldridge MW, Barnes JN. Association between serum prostacyclin and cerebrovascular reactivity in healthy young and older adults. Experimental Physiology. 2023 May 12. doi: 10.1112/EP090903. Epub ahead of print. PMID: 37170828.

48.

Corren J, Jackson DJ, Casale TB, Borish L, Rabe KF, Busse WW, Maspero JF, Jackson DJ, Daizadeh N, Altincatal A, Radwan A, Khodzhayev A, Djandji M, Jacob-Nara JA, Rowe PJ, Deniz Y. Dupilumab Efficacy in Patients with Uncontrolled Moderate-to-Severe Type 2 Asthma Regardless of Perennial Aeroallergen Sensitization. J Asthma Allergy. 2023 Mar 7;16:249-260. doi: 10.2147/JAA.S385645. PMID: 36915284; PMCID: PMC10007984.

University of Wisconsin Department of Pediatrics | Annual Report 2023

PUBLICATIONS

49.

Cuvelier GDE, Logan BR, Prockop SE, Buckley RH, Kuo CY, Griffith LM, Liu X, Yip A, Hershfield MS, Ayoub PG, Moore TB, Dorsey MJ, O’Reilly RJ, Kapoor N, Pai SY, Kapadia M, Ebens CL, Forbes Satter LR, Burroughs LM, Petrovic A, Chellapandian D, Heimall J, Shyr DC, Rayes A, Bednarski JJ, Chandra S, Chandrakasan S, Gillio AP, Madden L, Quigg TC, Caywood EH, Dávila Saldaña BJ, DeSantes K, Eissa H, Goldman FD, Rozmus J, Shah AJ, Vander Lugt MT, Thakar MS, Parrott RE, Martinez C, Leiding JW, Torgerson TR, Pulsipher MA, Notarangelo LD, Cowan MJ, Dvorak CC, Haddad E, Puck JM, Kohn DB. Outcomes following treatment for ADA-deficient severe combined immunodeficiency: a report from the PIDTC. Blood. 2022 Aug 18;140(7):685-705. doi: 10.1182/blood.2022016196. PMID: 35671392; PMCID: PMC9389638.

50. De Lange WJ, Farrell ET, Hernandez JJ, Stempien A, Kreitzer CR, Jacobs DR, Petty DL, Moss RL, Crone WC, Ralphe JC. cMyBP-C ablation in human engineered cardiac tissue causes progressive Ca2+handling abnormalities. J Gen Physiol. 2023 Apr 3;155(4):e202213204. doi: 10.1085/ jgp.202213204. Epub 2023 Mar 9. PMID: 36893011; PMCID: PMC10038829. 51.

Devries MK, Bochkov YA, Evans MD, Gern JE, Jackson DJ. Recent Clinical Isolates of Enterovirus D68 Have Increased Replication and Induce Enhanced Epithelial Immune Response Compared to the Prototype Fermon Strain. Viruses. 2023 May 31;15(6):1291. doi: 10.3390/v15061291. PMID: 37376591; PMCID: PMC10305710.

52.

D’Onofrio G, Cuccurullo C, Larsen SK, Severino M, D’Amico A, Brønstad K, AlOwain M, Morrison JL, Wheeler PG, Webb BD, Alfalah A, Iacomino M, Uva P, Coppola A, Merla G, Salpietro VD, Zara F, Striano P, Accogli A, Arnesen T, Bilo L. Novel biallelic variants expand the phenotype of NAA20-related syndrome. Clin Genet. 2023 May 16. doi: 10.1111/cge.14359. Epub ahead of print. PMID: 37191084.

53.

Damodharan S, Helgager J, Puccetti D. Indolent presentation of a diffuse midline glioma, H3 K27-altered. Childs Nerv Syst. 2022 Sep 12. doi: 10.1007/s00381-022-05668-4. Epub ahead of print. PMID: 36094605.

54.

Dapas M, Thompson EE, Wentworth-Sheilds W, Clay S, Visness CM, Calatroni A, Sordillo JE, Gold DR, Wood RA, Makhija M, Khurana Hershey GK, Sherenian MG, Gruchalla RS, Gill MA, Liu AH, Kim H, Kattan M, Bacharier LB, Rastogi D, Altman MC, Busse WW, Becker PM, Nicolae D, O’Connor GT, Gern JE, Jackson DJ, Ober C. Multi-omic association study identifies DNA methylation-mediated genotype and smoking exposure effects on lung function in children living in urban settings. PLoS Genet. 2023 Jan 13;19(1):e1010594. doi: 10.1371/journal. pgen.1010594. PMID: 36638096; PMCID: PMC9879483.

pediatrics.wisc.edu

PUBLICATIONS

55.

56.

57.

de Jesus AA, Chen G, Yang D, Brdicka T, Ruth NM, Bennin D, Cebecauerova D, Malcova H, Freeman H, Martin N, Svojgr K, Passo MH, Bhuyan F, Alehashemi S, Rastegar AT, Uss K, Kardava L, Marrero B, Duric I, Omoyinmi E, Peldova P, Lee CR, Kleiner DE, Hadigan CM, Hewitt SM, Pittaluga S, Carmona-Rivera C, Calvo KR, Shah N, Balascakova M, Fink DL, Kotalova R, Parackova Z, Peterkova L, Kuzilkova D, Campr V, Sramkova L, Biancotto A, Brooks SR, Manes C, Meffre E, Harper RL, Kuehn H, Kaplan MJ, Brogan P, Rosenzweig SD, Merchant M, Deng Z, Huttenlocher A, Moir SL, Kuhns DB, Boehm M, Skvarova Kramarzova K, Goldbach-Mansky R. Constitutively active Lyn kinase causes a cutaneous small vessel vasculitis and liver fibrosis syndrome. Nat Commun. 2023 Mar 17;14(1):1502. doi: 10.1038/ s41467-023-36941-y. PMID: 36932076; PMCID: PMC10022554. Delatorre RG, Sutter EN, Nemanich ST, Krach LE, Meekins G, Feyma T, Gillick BT. Anodal Contralesional tDCS Enhances CST Excitability Bilaterally in an Adolescent with Hemiparetic Cerebral Palsy: A Brief Report. Dev Neurorehabil. 2023 Mar 26:1-6. doi: 10.1080/17518423.2023.2193626. Epub ahead of print. PMID: 36967533. Desai AV, Gilman AL, Ozkaynak MF, Naranjo A, London WB, Tenney SC, Diccianni M, Hank JA, Parisi MT, Shulkin BL, Smith M, Moscow JA, Shimada H, Matthay KK, Cohn SL, Maris JM, Bagatell R, Sondel PM, Park JR, Yu AL. Outcomes Following GD2-Directed Postconsolidation Therapy for Neuroblastoma After Cessation of Random Assignment on ANBL0032: A Report From the Children’s Oncology Group. J Clin Oncol. 2022 Jul 15:JCO2102478. doi: 10.1200/JCO.21.02478. Epub ahead of print. PMID: 35839426.

58.

DeSanti RL, Cowan EA, Kory PD, Lasarev MR, Schmidt J, Al-Subu AM. Lung Ultrasound Artifact Findings in Pediatric Patients Admitted to the Intensive Care Unit for Acute Respiratory Failure. J Ultrasound. 2022 Dec;25(4):929937. doi: 10.1007/s40477-022-00675-2. Epub 2022 Apr 10. PMID: 35397743; PMCID: PMC8994848.

59.

Deshwar AR, Cytrynbaum C, Murthy H, Zon J, Chitayat D, Volpatti J, Newbury-Ecob R, Ellard S, Lango Allen H, Yu EP, Noche R, Walker S, Scherer SW, Mahida S, Elitt CM, Nicolas G, Goldenberg A, Saugier-Veber P, Lecoquierre F, Dabaj I, Meddaugh H, Marble M, Keppler-Noreuil KM, Drayson L, Barañano KW, Chassevent A, Agre K, Létard P, Bilan F, Le Guyader G, Laquerrière A, Ramsey K, Henderson L, Brady L, Tarnopolsky M, Bainbridge M, Friedman J, Capri Y, Athayde L, Kok F, Gurgel-Giannetti J, Ramos LLP, Blaser S, Dowling JJ, Weksberg R. Variants in CLDN5 cause a syndrome characterized by seizures, microcephaly and brain calcifications. Brain. 2022 Dec 8:awac461. doi: 10.1093/ brain/awac461. Epub ahead of print. PMID: 36477332.

60. DiPiero M, Rodrigues PG, Gromala A, Dean DC 3rd. Applications of advanced diffusion MRI in early brain development: a comprehensive review. Brain Struct Funct. 2022 Dec 31. doi: 10.1007/s00429-022-02605-8. Epub ahead of print. PMID: 36585970. 61.

Dissanayake E, Brockman-Schneider RA, Stubbendieck RM, Helling BA, Zhang Z, Bochkov YA, Kirkham C, Murphy TF, Ober C, Currie CR, Gern JE. Rhinovirus increases Moraxella catarrhalis adhesion to the respiratory epithelium. Front Cell Infect Microbiol. 2023 Jan 17;12:1060748. doi: 10.3389/fcimb.2022.1060748. PMID: 36733852; PMCID: PMC9886879.

University of Wisconsin Department of Pediatrics | Annual Report 2023

PUBLICATIONS

62.

63.

Dunbar PJ, Sobotka SA, Rodean J, Pulcini CD, Macy ML, Thomson J, Harris D, Coller RJ, Desmarais A, Hall M, Berry JG. Prevalence of and Spending on Ear, Nose, Throat, and Respiratory Infections among Children with Chronic Complex Conditions. Acad Pediatr. 2022 Sep 16;.doi: 10.1016/j.acap.2022.07.004. Epub ahead of print. PMID: 36122827. Duvenhage J, Draper HR, Garcia-Prats AJ, Winckler J, Hesseling AC, Schaaf HS. Hepatocellular Injury in Children Treated for Rifampicin-resistant Tuberculosis: Incidence, Etiology and Outcome. Pediatr Infect Dis J. 2022 Dec 1;41(12):953-958. doi: 10.1097/ INF.0000000000003690. Epub 2022 Sep 6. PMID: 36102699.

64. Dvorak CC, Haddad E, Heimall J, Dunn E, Cowan MJ, Pai SY, Kapoor N, Satter LF, Buckley RH, O’Reilly RJ, Chandra S, Bednarski JJ, Williams O, Rayes A, Moore TB, Ebens CL, Davila Saldana BJ, Petrovic A, Chellapandian D, Cuvelier GDE, Vander Lugt MT, Caywood EH, Chandrakasan S, Eissa H, Goldman FD, Shereck E, Aquino VM, Desantes KB, Madden LM, Miller HK, Yu L, Broglie L, Gillio A, Shah AJ, Knutsen AP, Andolina JP, Joshi AY, Szabolcs P, Kapadia M, Martinez CA, Parrot RE, Sullivan KE, Prockop SE, Abraham RS, Thakar MS, Leiding JW, Kohn DB, Pulsipher MA, Griffith LM, Notarangelo LD, Puck JM. The diagnosis of severe combined immunodeficiency: Implementation of the PIDTC 2022 Definitions. J Allergy Clin Immunol. 2023 Feb;151(2):547555.e5. doi: 10.1016/j.jaci.2022.10.021. Epub 2022 Nov 28. PMID: 36456360; PMCID: PMC9905305. 65.

66. Elgin TG, Berger JN, Thomas BA, Colaizy TT, Klein JM. Ventilator Management in Extremely Preterm Infants. Neoreviews. 2022 Oct 1;23(10):e661-e676. doi: 10.1542/neo.2310-e661. PMID: 36180732. 67.

Ellis P, Greeley C, Green A, Javier J, Mathur M, Mattson G, Nathawad R, Peltier C, and The AAP Council on Community Pediatrics. The Evolution of the Community Pediatrician. Pediatrics. 2023 May.

68.

Engen R, Shepherd D, Bradford MC, Foutz J, Bartosh SM, Smith JM. Impact of multiorgan and kidney-pancreas allocation policies on pediatric kidney-alone transplant candidates in the United States. Pediatr Transplant. 2022 Dec;26(8):e14394. doi: 10.1111/petr.14394. Epub 2022 Sep 22. PMID: 36134704.

69.

Engen RM, Smith JM, Bartosh SM. The kidney allocation system and pediatric transplantation at 5 years. Pediatr Transplant. 2022 Nov;26(7):e14369. doi: 10.1111/petr.14369. Epub 2022 Aug 2. PMID: 35919967.

70.

Erbe AK, Diccianni MB, Mody R, Naranjo A, Zhang FF, Birstler J, Kim K, Feils AS, Hung JT, London WB, Shulkin BL, Mathew V, Parisi MT, Servaes S, Asgharzadeh S, Maris JM, Park J, Yu AL, Sondel PM, Bagatell R. KIR/KIR-ligand genotypes and clinical outcomes following chemoimmunotherapy in patients with relapsed or refractory neuroblastoma: a report from the Children’s Oncology Group. J Immunother Cancer. 2023 Feb;11(2):e006530. doi: 10.1136/ jitc-2022-006530. PMID: 36822669; PMCID: PMC9950969.

Edmonson MB, Francis DO, Coller RJ. Patient Characteristics and Postoperative Mortality in Children Undergoing Tonsillectomy-Reply. JAMA. 2022 Nov 1;328(17):1771. doi: 10.1001/ jama.2022.16521. PMID: 36318136.

pediatrics.wisc.edu

PUBLICATIONS

71.

Ezeh N, Ardalan K, Buhr KA, Nguyen C, Al Ahmed O, Ardoin SP, Barton V, Bell S, Brandling-Bennett H, Castelo-Soccio L, Chiu YE, Chong BF, Co DO, Lara-Corrales I, Cintosun A, Curran ML, Diaz LZ, Elman SA, Faith EF, Garcia-Romero MT, GrossmanKranseler J, Hogeling M, Hudson AD, Hunt RD, Ibler EM, Marques MC, Monir RL, Oza V, Paller AS, Putterman E, RodriguezSalgado P, Schoch JJ, Truong A, Wang J, Lee LW, Vleugels RA, Klein-Gitelman MS, von Scheven E, Werth VP, Arkin LM. Crosssectional characteristics of pediatric-onset discoid lupus erythematosus: Results of a multicenter, retrospective cohort study. J Am Acad Dermatol. 2022 Sep;87(3):559-566. doi: 10.1016/j.jaad.2022.04.028. Epub 2022 Apr 26. PMID: 35487332.

72.

Falkiewicz MK, Su R, Jones SL, Shayan M, Farhat WA, Peters ME. Pediatric Sedation Unit: A Safe, Effective, and Satisfactory Alternative to Outpatient Pediatric Urological Procedures Under Anesthesia. J Urol. 2023 Mar. doi: 10.1097/UPJ.0000000000000364.

73.

Fang JL, Umoren RA, Whyte H, Limjoco J, Makkar A, Behl S, Lo MD, White L, Culjat M, Taylor JS, Kathuria S, Webb MO, Schad T, Shafranski S, Yankanah R, Herrin J, Demaerschalk BM. Evaluating the feasibility of a multicenter teleneonatology clinical effectiveness trial. Pediatr Res. 2023 May 19;. doi: 10.1038/s41390-023-02659-2. [Epub ahead of print] PMID: 37208433.

74.

Farooque A, Osman F, Carroll CB, Ewer S, Lee-Miller C, Tevaarwerk A, Pophali PA. PreTreatment Left Ventricular Ejection Fraction Assessment and Long-Term Cardiovascular Outcomes in Adolescent and Young Adult Lymphoma Survivors. J Adolesc Young Adult Oncol. 2022 Sep 2. doi: 10.1089/ jayao.2022.0062. Epub ahead of print. PMID: 36067076.

75.

Fathman CG, Yip L, Gómez-Martín D, Yu M, Seroogy CM, Hurt CR, Lin JT, Jenks JA, Nadeau KC, Soares L. How GRAIL controls Treg function to maintain self-tolerance. Front Immunol. 2022 Dec 8; 13:1046631. doi: 10.3389/ fimmu.2022.1046631. PMID: 36569931; PMCID: PMC9773990.

76.

Feils AS, Erbe AK, Birstler J, Kim K, Hoch U, Currie SL, Nguyen T, Yu D, Siefker-Radtke AO, Tannir N, Tolaney SM, Diab A, Sondel PM. Associations between KIR/KIR-ligand genotypes and clinical outcome for patients with advanced solid tumors receiving BEMPEG plus nivolumab combination therapy in the PIVOT-02 trial. Cancer Immunol Immunother. 2023 Feb 23. doi: 10.1007/s00262-02303383-w. Epub ahead of print. PMID: 36823323.

77.

Fenske RJ, Weeks AM, Daniels M, Nall R, Pabich S, Brill AL, Peter DC, Punt M, Cox ED, Davis DB, Kimple ME. Plasma Prostaglandin E2 Metabolite Levels Predict Type 2 Diabetes Status and OneYear Therapeutic Response Independent of Clinical Markers of Inflammation. Metabolites. 2022 Dec 8;12(12):1234. doi: 10.3390/ metabo12121234. PMID: 36557272; PMCID: PMC9783643.

78.

Fister AM, Horn A, Huttenlocher A. Keratinocyte dynamics modulate the spatial organization of redox signaling during sensory neuron regeneration. [preprint]. 2023 March. doi: 2023.03.14.532628.

79.

Fleishman R, McAdams RM, Carter BS, Gautham KS. Narrative neonatology: integrating narrative medicine into the neonatal intensive care unit. J Perinatol. 2022 Nov 21. doi: 10.1038/s41372-022-01565-5. Epub ahead of print. PMID: 36414736.

University of Wisconsin Department of Pediatrics | Annual Report 2023

PUBLICATIONS

80. Forrest CB, Schuchard J, Bruno C, Amaral S, Cox ED, Flynn KE, Hinds PS, Huang IC, Kappelman MD, Krishnan JA, Kumar RB, Lai JS, Paller AS, Phipatanakul W, Schanberg LE, Sumino K, Weitzman ER, Reeve BB. SelfReported Health Outcomes of Children and Youth with 10 Chronic Diseases. J Pediatr. 2022 Jul;246:207-212.e1. doi: 10.1016/j. jpeds.2022.02.052. Epub 2022 Mar 2. PMID: 35247394. 81.

Franks AM, Calamur N, Dobrian A, Danielsen M, Neumann SA, Cowan EA, Weiler T. Rank and Tenure Amongst Faculty at Academic Medical Centers: A Study of More Than 50 Years of Gender Disparities. Academic Medicine. 2022 July; 97 (7): 1038-1048. doi: 10.1097/ ACM.0000000000004706

82.

Fulkerson PC, Lussier SJ, Bendixsen CG, Castina SM, Gebretsadik T, Marlin JS, Russell PB, Seibold MA, Everman JL, Moore CM, Snyder BM, Thompson K, Tregoning GS, Wellford S, Arbes SJ, Bacharier LB, Calatroni A, Camargo CA, Dupont WD, Furuta GT, Gruchalla RS, Gupta RS, Hershey GK, Jackson DJ, Johnson CC, Kattan M, Liu AH, Murrison L, Oâ Connor GT, Phipatanakul W, Rivera-Spoljaric K, Rothenberg ME, Seroogy CM, Teach SJ, Zoratti EM, Togias A, Hartert TV. Human Epidemiology and RespOnse to SARS-CoV-2 (HEROS): Objectives, Design and Enrollment Results of a 12-City Remote Observational Surveillance Study of Households with Children using Direct-to-Participant Methods. medRxiv [Preprint]. 2022 Jul 10:2022.07.09.22277457. doi: 10.1101/2022.07.09.22277457. PMID: 35860216; PMCID: PMC9298141.

83.

Gafar F, Wasmann RE, McIlleron HM, Aarnoutse RE, Schaaf HS, Marais BJ, Agarwal D, Antwi S, Bang ND, Bekker A, Bell DJ, Chabala C, Choo L, Davies GR, Day JN, Dayal R, Denti P, Donald PR, Engidawork E, Garcia-Prats AJ, Gibb D, Graham SM, Hesseling AC, Heysell SK, Idris MI, Kabra SK, Kinikar A, Hemanth Kumar AK, Kwara A, Lodha R, Magis-Escurra C, Martinez N, Mathew BS, Mave V, Mduma E, Mlotha-Mitole R, Mpagama SG, Mukherjee A, Nataprawira HM, Peloquin CA, Pouplin T, Ramachandran G, Ranjalkar J, Roy V, Ruslami R, Shah I, Singh Y, Sturkenboom MGG, Svensson EM, Swaminathan S, Thatte U, Thee S, Thomas TA, Tikiso T, Touw DJ, Turkova A, Velpandian T, Verhagen LM, Winckler JL, Yang H, Yunivita V, Taxis K, Stevens J, Alffenaar JC; Global Collaborative Group for MetaAnalysis of Paediatric Individual Patient Data in Pharmacokinetics of Anti-TB Drugs. Global estimates and determinants of antituberculosis drug pharmacokinetics in children and adolescents: a systematic review and individual patient data meta-analysis. Eur Respir J. 2022 Nov 3:2201596. doi: 10.1183/13993003.015962022. Epub ahead of print. PMID: 36328357.

84. Gaffin JM, Petty CR, Sorkness RL, Denlinger LC, Phillips BR, Ly NP, Gaston B, Ross K, Fitzpatrick A, Bacharier LB, DeBoer MD, Teague WG, Wenzel SE, Ramratnam S, Israel E, Mauger DT, Phipatanakul W; National Heart, Lung, and Blood Institute’s Severe Asthma Research Program-3 Investigators. Determinants of lung function across childhood in the Severe Asthma Research Program (SARP) 3. J Allergy Clin Immunol. 2023 Jan;151(1):138-146.e9. doi: 10.1016/j. jaci.2022.08.014. Epub 2022 Aug 27. PMID: 36041656; PMCID: PMC9825637. 85.

Garcia-Prats AJ, Starke JR, Waning B, Kaiser B, Seddon JA. New Drugs and Regimens for Tuberculosis Disease Treatment in Children and Adolescents. J Pediatric Infect Dis Soc. 2022 Oct 31;11(Supplement_3):S101-S109. doi: 10.1093/jpids/piac047. PMID: 36314547.

pediatrics.wisc.edu

PUBLICATIONS

86.

Gavidia R, Whitney DG, Hershner S, Selkie EM, Tauman R, Dunietz GL. Gender identity and transition: relationships with sleep disorders in US youth. J Clin Sleep Med. 2022 Aug 1;. doi: 10.5664/jcsm.10158. [Epub ahead of print] PMID: 35912700.

87.

Gern JE, Pavord ID. Challenges and Opportunities in Asthma Prevention and Treatment. J Allergy Clin Immunol Pract. 2023 Mar;11(3):748-749. doi: 10.1016/j. jaip.2022.12.032. PMID: 36894276.

88.

Gibson C, Schumann C, Neuschel K, McBride JA. COVID-19 Vaccination Coverage Among People Experiencing Homelessness in a Highly Vaccinated Midwest County-Dane County, Wisconsin, 2021. J Infect Dis. 2022 Oct 7;226(Supplement_3):S335-S339. doi: 10.1093/infdis/jiac303. PMID: 36208167.

89.

Glanz H, Damodharan SN, Smith-Simmer K, Helgager J, Puccetti D. Concurrent highgrade glioma with cavernous malformations and pathogenic variants in PDCD10 and SMARCA4. Childs Nerv Syst. 2023 Jun 16. doi: 10.1007/ s00381-023-06026-8. Epub ahead of print. PMID: 37328659.

90. Goebel CP, Song YS, Zaitoun IS, Wang S, Potter HAD, Sorenson CM, Sheibani N. Adenosine Receptors Expression in Human Retina and Choroid with Age-related Macular Degeneration. J Ophthalmic Vis Res. 2023 JanMar;18(1):51-59. doi: 10.18502/jovr.v18i1.12725. eCollection 2023 Jan-Mar. PMID: 36937188; PMCID: PMC10020792. 91.

Goetz EM, Tomlin BD, Rinaldo KE, Baumann-Blackmore NL, Petro RL, Smith BB, Zapata JY, Lasarev MR, McBride EB, Kaluarachchi DC. Oxygen Saturation Profiles in Healthy Term Infants in Early Postnatal Life. Am J Perinatol. 2022 Jul 10. doi: 10.1055/s0042-1749630. Epub ahead of print. PMID: 35815572.

92.

Gruen LJ, Lee-Miller CA, Osman F, Parkes A. Benefit of Interdisciplinary Care in Resource Identification in an Adolescent and Young Adult Oncology Care Model. J Adolesc Young Adult Oncol. 2023 Jan 2;. doi: 10.1089/ jayao.2021.0197. [Epub ahead of print] PMID: 36595361.

93.

Harer MW, Charlton JR. Urine or You’re Out? Perspectives on Urinary Output Thresholds in the Neonatal Acute Kidney Injury Definition. Clin J Am Soc Nephrol. 2022 Jul;17(7):939-941. doi: 10.2215/CJN.06010522. Epub 2022 Jun 28. PMID: 35764394; PMCID: PMC9269636.

94. Harer MW, Condit PE, Chuck JE, Lasarev MR, Chock VY. Renal oxygenation measured by near-infrared spectroscopy in preterm neonates in the first week. Pediatr Res. 2022 Dec;92(6):1744-1748. doi: 10.1038/s41390-02202036-5. Epub 2022 Mar 30. PMID: 35354931; PMCID: PMC9522888. 95.

Harer MW, Gadek L, Rothwell AC, Richard L, Starr MC, Adegboro CO. Correlation of Renal Tissue Oxygenation to Venous, Arterial, and Capillary Blood Gas Oxygen Saturation in Preterm Neonates. Am J Perinatol. 2023 Jan 29. doi: 10.1055/s-0043-1761296. Epub ahead of print. PMID: 36709760.

96. Harer MW, Rumpel JA, Stoops C, Slagle CL, Liberio B, Daniel J, Hoffman SB, Agarwal N, Khattab MG, Rais-Bahrami K, Perazzo S. Current state of renal NIRS monitoring in the NICU: results from a CHNC Survey. J Perinatol. 2023 Mar 17;. doi: 10.1038/s41372-023-01648-x. [Epub ahead of print] PMID: 36932136. 97.

Heaton AR, Rehani PR, Hoefges A, Lopez AF, Erbe AK, Sondel PM, Skala MC. Single cell metabolic imaging of tumor and immune cells in vivo in melanoma bearing mice. Front Oncol. 2023 Mar 20;13:1110503. doi: 10.3389/ fonc.2023.1110503. PMID: 37020875; PMCID: PMC10067577.

University of Wisconsin Department of Pediatrics | Annual Report 2023

PUBLICATIONS

98. Hess E, Anandan A, Osman F, Lee-Miller C, Parkes A. Disparities in Treatment Satisfaction and Supportive Care Receipt for Young Adult Oncology Patients on the Basis of Residential Location. JCO Oncol Pract. 2022 Sep;18(9):e1542-e1552. doi: 10.1200/ OP.21.00818. Epub 2022 Jun 13. PMID: 35696631. 99.

Hess NJ, Turicek DP, Riendeau J, McIlwain SJ, Contreras Guzman E, Nadiminti K, Hudson A, Callander NS, Skala MC, Gumperz JE, Hematti P, Capitini CM. Inflammatory CD4/ CD8 double-positive human T cells arise from reactive CD8 T cells and are sufficient to mediate GVHD pathology. Sci Adv. 2023 Mar 24;9(12):eadf0567. doi: 10.1126/sciadv.adf0567. Epub 2023 Mar 24. PMID: 36961891; PMCID: PMC10038349.

100. Hingorani P, Krailo M, Buxton A, Hutson P, Sondel PM, Diccianni M, Yu A, Morris CD, Womer RB, Crompton B, Randall RL, Teot LA, DuBois SG, Janeway KA, Gorlick RG, Isakoff MS. Phase 2 study of anti-disialoganglioside antibody, dinutuximab, in combination with GMCSF in patients with recurrent osteosarcoma: A report from the Children’s Oncology Group. Eur J Cancer. 2022 Sep;172:264-275. doi: 10.1016/j. ejca.2022.05.035. Epub 2022 Jul 6. PMID: 35809374; PMCID: PMC9631806. 101. Hoefges A, McIlwain SJ, Erbe AK, Mathers NN, Xu AE, Melby D, Tetreault K, Le TQ, Kim K, Pinapati RS, Garcia B, Patel J, Heck M, Feils A, Tsarovsky N, Hank JA, Morris ZS, Ong IM, Sondel PM. Antibody landscape of C57BL/6 mice cured of B78 melanoma via immunotherapy. bioRxiv [Preprint]. 2023 Apr 28:2023.02.24.529012. doi: 10.1101/2023.02.24.529012. PMID: 36896021; PMCID: PMC9996675.

102. Hose BZ, Carayon P, Hoonakker PLT, Ross JC, Eithun BL, Rusy DA, Kohler JE, Brazelton TB 3rd, Dean SM, Kelly MM. Managing multiple perspectives in the collaborative design process of a team health information technology. Appl Ergon. 2022 Aug 16;106:103846. doi: 10.1016/j. apergo.2022.103846. Epub ahead of print. PMID: 35985249. 103. House TR, Wightman A. Enabling flourishing: novel approaches in palliative medicine for children with advanced kidney disease. Curr Opin Nephrol Hypertens. 2023 Jan 1;32(1):4148. doi: 10.1097/MNH.0000000000000839. Epub 2022 Oct 11. PMID: 36250456. 104. Howell KD, Kelly MM, DeMuri GP, McBride JA, Katz B, Edmonson MB, Sklansky DJ, Shadman KA, Ehlenbach ML, Butteris SM, Warner G, Zhao Q, Coller RJ. COVID-19 Vaccination Intentions for Children With Medical Complexity. Hosp Pediatr. 2022 Aug 30;.doi: 10.1542/hpeds.2022-006544. [Epub ahead of print] PMID: 36039687. 105. Huang L, Lai HJ, Antos N, Rock MJ, Asfour F, Howenstine M, Gaffin JM, Farrell PM. Defining and identifying early-onset lung disease in cystic fibrosis with cumulative clinical characteristics. Pediatr Pulmonol. 2022 Oct;57(10):2363-2373. doi: 10.1002/ ppul.26040. Epub2022 Jun 25. PMID: 35712759; PMCID: 9489630. 106. Hughes J, Nielsen J, Buck WC, Mutemba C, Garcia-Prats AJ. QT Interval Prolongation and Second-line Antituberculosis Medicines in Children: An Update and Practical Considerations for Noncardiologists. Pediatr Infect Dis J. 2023 Mar 1;42(3):e80-e83. doi: 10.1097/INF.0000000000003742. Epub 2023 Feb 3. PMID: 36749926.

pediatrics.wisc.edu

PUBLICATIONS

107. Hunter JE, Jenkins CL, Bulkley JE, Gilmore MJ, Lee K, Pak CM, Wallace KE, Buchanan AH, Foreman AKM, Freed AS, Goehringer S, Manickam K, Meeks NJL, Ramos EM, Shah N, Steiner RD, Subramanian SL, Trotter T, Webber EM, Williams MS, Goddard KAB, Powell BC; ClinGen. ClinGen’s Pediatric Actionability Working Group: Clinical actionability of secondary findings from genome-scale sequencing in children and adolescents. Genet Med. 2022 Jun;24(6):1328-1335. doi: 10.1016/j. gim.2022.02.019. Epub 2022 Mar 25. PMID: 35341655; PMCID: PMC9156571. 108. Idol RA, Bhattacharya S, Huang G, Song Z, Huttenlocher A, Keller NP, Dinauer MC. Neutrophil and Macrophage NADPH Oxidase 2 Differentially Control Responses to Inflammation and to Aspergillus fumigatus in Mice. J Immunol. 2022 Nov 15;209(10):19601972. doi: 10.4049/jimmunol.2200543. PMID: 36426951; PMCID: PMC9643661. 109. Jackson DJ, Bacharier LB, Gergen PJ, Gagalis L, CalatroniA, Wellford S, Gill MA, Stokes J, Liu AH, Gruchalla RS, Cohen RT, Makhija M, Khurana Hershey GK, O’Connor GT, Pongracic JA, Sherenian MG, Rivera-Spoljaric K, Zoratti EM, Teach SJ, Kattan M, Dutmer CM, Kim H, Lamm C, Sheehan WJ, Segnitz RM, DillMcFarland KA, Visness CM, Becker PM, Gern JE, Sorkness CA, Busse WW, Altman MC; US National Institute of Allergy and Infectious Disease’s Inner City Asthma Consortium. Mepolizumab for urban children with exacerbation-prone eosinophilic asthma in the USA (MUPPITS-2):a randomised, double-blind, placebo-controlled, parallel-group trial. Lancet. 2022 Aug 13;400(10351):502-511. doi: 10.1016/ S0140-6736(22)01198-9. PMID: 35964610.

110. Jackson DJ, Bacharier LB, Phipatanakul W, Sher L, Domingo C, Papadopoulos N, Modena B, Li N, Xia C, Kamal MA, Dillon M, Wolfe K, Gall R, Amin N, Mannent LP, Laws E, Rowe PJ, Jacob-Nara JA, Deniz Y, Lederer DJ, Hardin M, Xu C. Dupilumab pharmacokinetics and effect on type 2 biomarkers in children with moderateto-severe asthma. Ann Allergy Asthma Immunol. 2023 Mar 21:S1081-1206(23)00180-1. doi: 10.1016/j.anai.2023.03.014. Epub ahead of print. PMID: 36958470. 111.

Jackson DJ, Golden RN. New Developments in Our Understanding of the Origins and Treatment of Asthma. WMJ. 2022 Jul;121(2):167-168. PMID: 35857700.

112.

Jagodinsky JC, Bates AM, Clark PA, Sriramaneni RN, Havighurst TC, Chakravarty I, Nystuen EJ, Kim K, Sondel PM, Jin WJ, Morris ZS. Local TLR4 stimulation augments in situ vaccination induced via local radiation and antiCTLA-4 checkpoint blockade through induction of CD8 T-cell independent Th1 polarization. J Immunother Cancer. 2022 Oct;10(10):e005103. doi: 10.1136/jitc-2022-005103. PMID: 36192087; PMCID: PMC9535200.

113.

Jarvis JM, Roy J, Schmithorst V, Lee V, Devine D, Meyers B, Munjal N, Clark RSB, Kochanek PM, Panigrahy A, Ceschin R, Fink EL. Limbic pathway vulnerability associates with neurologic outcome in children after cardiac arrest. Resuscitation. 2023 Jan;182:109634. doi: 10.1016/j.resuscitation.2022.10.026. Epub 2022 Nov 3. PMID: 36336196.

114. Jennings JF, Nett S, Umoren R, Murray R, Kessel A, Napolitano N, Adu-Darko M, ..., Mallory P, Al-Subu A, Tarquinio K, Glater L, et al. The Association of Teamwork and Adverse Tracheal Intubation–Associated Events in Advanced Airway Management in the PICU. Journal of Pediatric Intensive Care. 10.1055/s0042-1756715.

University of Wisconsin Department of Pediatrics | Annual Report 2023

PUBLICATIONS

115.

Jewell T, Arendt D, Haffley K, Beversdorf A, St Clair NE, Hsu D. Encephalopathy with Akinetic Mutism in a Child With COVID-19 Infection: A Case Report. WMJ.2022 Oct;121(3):E42-E45. PubMed PMID: 36301657.

116. Jolliff A, Werner NE, Barton HJ, Howell KD, Kelly MM, Morgen M, Ehlenbach M, Warner G, Katz B, Kieren M, DeMuri G, Coller RJ. Caregiver perceptions of in-home COVID-19 testing for children with medical complexity: a qualitative study. BMC Pediatr. 2022 Sep 8;22(1):533.doi: 10.1186/s12887-022-03550-5. PMID: 36076181; PMCID: 9452877. 117.

Kabakov SA, Crary E, Menna V, Razo ER, Eickhoff JC, Dulaney NR, Drew JR Jr, Bach KM, Poole AM, Stumpf M, Mitzey AM, Malicki KB, Schotzko ML, Pickett KA, SchultzDarken NJ, Emborg ME, O’Connor DH, Golos TG, Mohr EL, Ausderau KK. Quantification of early gait development: Expanding the application of Catwalk technology to an infant rhesus macaque model. J Neurosci Methods. 2023 Feb 3; 388:109811. doi: 10.1016/j. jneumeth.2023.109811. Epub ahead of print. PMID: 36739916.

118. Kamps NN, Banks R, Reeder RW, Berg RA, Newth CJ, Pollack MM, Meert KL, Carcillo JA, Mourani PM, Sorenson S, Varni JW, Cengiz P, Zimmerman JJ; Life After Pediatric Sepsis Evaluation (LAPSE) Investigators. The Association of Early Corticosteroid Therapy With Clinical and Health-Related Quality of Life Outcomes in Children With Septic Shock. Pediatr Crit Care Med. 2022 Sep 1;23(9):687697. doi: 10.1097/PCC.0000000000003009. Epub 2022 Jun 10. Erratum in: Pediatr Crit Care Med. 2023 Apr 1;24(4):e212. PMID: 35695852; PMCID: PMC9444900.

119. Kelly MM, Hoonakker PLT, Nacht CL, Smith CA, Dean SM, Sklansky DJ, Smith W, Sprackling CM, Zellmer BM, Coller RJ. Parent Perspectives on Sharing Pediatric Hospitalization Clinical Notes. Pediatrics. 2023 Jan 1;151(1). doi: 10.1542/peds.2022-057756. PMID: 36450655; PMCID: PMC9998186. 120. Keppler-Noreuil KM, Burton-Akright J, Kleiner DE, Sapp JC, Lindhurst MJ, Han CG, Biesecker LG, GochuicoBR. Phenotypic Features of Cystic Lung Disease in Proteus Syndrome. Ann Am Thorac Soc. 2022 Jul 15. doi: 10.1513/AnnalsATS.202111-1214OC. Epub ahead of print. PMID: 35839129. 121.

Kharrazi M, Sacramento C, Comeau AM, Hale JE, Caggana M, Kay DM, Lee R, Reilly B, Thompson JD, Nasr SZ, Kleyn M, Hoffman G, Baker MW, Clarke C, Harris CL, Dorley MC, Fryman H, Sutaria A, Hietala A, Winslow H, Richards H, Therrell BL. Missed Cystic Fibrosis Newborn Screening Cases Due to Immunoreactive Trypsinogen Levels below Program Cutoffs: A National Survey of Risk Factors. Int J Neonatal Screen. 2022 Oct 27;8(4):58. doi: 10.3390/ijns8040058. PMID: 36412584.

122. Kirmani S, Woodard PK, Shi L, Hamza TH, Canter CE, Colan SD, Pahl E, Towbin JA, Webber SA, Rossano JW, Everitt MD, Molina KM, Kantor PF, Jefferies JL, Feingold B, Addonizio LJ, Ware SM, Chung WK, Ballweg JA, Lee TM, Bansal N, Razoky H, Czachor J, Lunze FI, Marcus E, Commean P, Wilkinson JD, Lipshultz SE. Cardiac imaging and biomarkers for assessing myocardial fibrosis in children with hypertrophic cardiomyopathy. Am Heart J. 2023 Jun 12;264:153-162. doi: 10.1016/j. ahj.2023.06.005. Epub ahead of print. PMID: 37315879. 123. Klass P, Heard-Garris N, Navsaria D. Effective Communication for Child Advocacy: Getting the Message out Beyond Clinic Walls. Pediatr Clin North Am. 2023 Feb;70(1):165-179. doi: 10.1016/j.pcl.2022.09.015. PMID: 36402466.

pediatrics.wisc.edu

PUBLICATIONS

124. Kloster HM, Coller RJ. Decisions, Defaults, or Disparities: Hospital Locations for Children Assisted by Technology. Pediatrics. 2023 Mar 20:e2022060878. doi: 10.1542/peds.2022060878. Epub ahead of print. PMID: 36938619. 125. Knapp EA, Kress AM, Parker CB, Page GP, McArthur K, Gachigi KK, Alshawabkeh AN, Aschner JL, Bastain TM, Breton CV, Bendixsen CG, Brennan PA, Bush NR, Buss C, Camargo CA Jr, Catellier D, Cordero JF, Croen L, Dabelea D, Deoni S, D’Sa V, Duarte CS, Dunlop AL, Elliott AJ, Farzan SF, Ferrara A, Ganiban JM, Gern JE, Giardino AP, Towe-Goodman NR, Gold DR, Habre R, Hamra GB, Hartert T, Herbstman JB, Hertz-Picciotto I, Hipwell AE, Karagas MR, Karr CJ, Keenan K, Kerver JM, Koinis-Mitchell D, Lau B, Lester BM, Leve LD, Leventhal B, LeWinn KZ, Lewis J, Litonjua AA, Lyall K, Madan JC, McEvoy CT, McGrath M, Meeker JD, Miller RL, Morello-Frosch R, Neiderhiser JM, O’Connor TG, Oken E, O’Shea M, Paneth N, Porucznik CA, Sathyanarayana S, Schantz SL, Spindel ER, Stanford JB, Stroustrup A, Teitelbaum SL, Trasande L, Volk H, Wadhwa PD, Weiss ST, Woodruff TJ, Wright RJ, Zhao Q, Jacobson LP, Environmental Influences On Child Health Outcomes OBOPCF. The Environmental influences on Child Health Outcomes (ECHO)wide Cohort. Am J Epidemiol. 2023 Mar 24:kwad071. doi: 10.1093/aje/kwad071. Epub ahead of print. PMID: 36963379. 126. Koenig MR, Mitzey AM, Morgan TK, Zeng X, Simmons HA, Mejia A, Leyva Jaimes F, Keding LT, Crooks CM, Weiler AM, Bohm EK, Aliota MT, Friedrich TC, Mohr EL, Golos TG. Infection of the maternal-fetal interface and vertical transmission following low-dose inoculation of pregnant rhesus macaques (Macaca mulatta) with an African-lineage Zika virus. PLoS One. 2023 May 4;18(5):e0284964. doi: 10.1371/ journal.pone.0284964. PMID: 37141276; PMCID: PMC10159132.

127. Kotas ME, O’Leary CE, Locksley RM. Tuft Cells: Context- and Tissue-Specific Programming for a Conserved Cell Lineage. Annu Rev Pathol. 2023 Jan 24;18:311-335. doi: 10.1146/annurevpathol-042320-112212. Epub 2022 Nov 9. PMID: 36351364. 128. Kravtsov DS, Erbe AK, Sondel PM, Rakhmilevich AL. Roles of CD4+ T cells as mediators of antitumor immunity. Front Immunol. 2022 Sep 9;13:972021. doi: 10.3389/ fimmu.2022.972021. PMID: 36159781; PMCID: PMC9500154. 129. Lastra AC, Ingram D, Park J, James E, Matthews C, Canapari C, Mansukhani M, Stahl SM. Moving toward standardization: physician reporting of sleep studies. J Clin Sleep Med. 2023 Mar 1;19(3):595-603. doi: 10.5664/ jcsm.10442. PMID: 36546360; PMCID: PMC9978423. 130. Laubhahn K, Phelan KJ, Jackson DJ, Altman MC, Schaub B. What Have Mechanistic Studies Taught Us About Childhood Asthma? J Allergy Clin Immunol Pract. 2023 Mar;11(3):684-692. doi: 10.1016/j.jaip.2023.01.004. Epub 2023 Jan 14. PMID: 36649800. 131.

Lee M, Condit P, Lee-Miller C, Tiedt K. Constipation and Abdominal Distention in a 5-Week-Old Male. Clin Pediatr (Phila). 2023 Apr 11;:99228231164992. doi: 10.1177/00099228231164992. [Epub ahead of print] PMID: 37038756.

132. Lee UN, Su X, Hieber DL, Tu WC, McManamen AM, Takezawa MG, Hassan GW, Chan TC, Adams KN, Wald ER, DeMuri GP, Berthier E, Theberge AB, Thongpang S. CandyCollect: athome saliva sampling for capture of respiratory pathogens. Lab Chip. 2022 Sep 13;22(18):35553564. doi: 10.1039/d1lc01132d. PMID: 35983761; PMCID: PMC9931141.

University of Wisconsin Department of Pediatrics | Annual Report 2023

PUBLICATIONS

133. Li C, Farooqui M, Yada RC, Cai JB, Huttenlocher A, Beebe DJ. The effect of whole blood logistics on neutrophil non-specific activation and kinetics ex vivo. Res Sq. 2023 May 9;. doi: 10.21203/rs.3.rs-2837704/v1. PMID: 37214903; PMCID: PMC10197797. 134. Lim SY, Cengiz P. Opioid tolerance and opioidinduced hyperalgesia: Is TrkBmodulation a potential pharmacological solution? Neuropharmacology. 2022 Sep 19;220:109260. doi: 10.1016/j.neuropharm.2022.109260. Epub ahead of print. PMID: 36165856. 135. Logun M, Colonna MB, Mueller KP, Ventarapragada D, Rodier R, Tondepu C, Piscopo NJ, Das A, Chvatal S, Hayes HB, Capitini CM, Brat DJ, Kotanchek T, Edison AS, Saha K, Karumbaiah L. Label-free in vitro assays predict the potency of anti-disialoganglioside chimeric antigen receptor T-cell products. Cytotherapy. 2023 Jun;25(6):670-682. doi: 10.1016/j.jcyt.2023.01.008. Epub 2023 Feb 26. PMID: 36849306; PMCID: PMC10159906. 136. Loi MV, Lee JH, Huh JW, Mallory P, Napolitano N, Shults J, Krawiec C, Shenoi A, Polikoff L, AlSubu A, Sanders R Jr, Toal M, Branca A, GlaterWelt L, Ducharme-Crevier L, Breuer R, Parsons S, Harwayne-Gidansky I, Kelly S, Motomura M, Gladen K, Pinto M, Giuliano J Jr, Bysani G, Berkenbosch J, Biagas K, Rehder K, Kasagi M, Lee A, Jung P, Shetty R, Nadkarni V, Nishisaki A; National Emergency Airway Registry for Children (NEAR4KIDS) Investigators, Pediatric Acute Lung Injury, Sepsis Investigators (PALISI) Network. Ketamine Use in the Intubation of Critically Ill Children with Neurological Indications: A Multicenter Retrospective Analysis. Neurocrit Care. 2023 May 9. doi: 10.1007/s12028-023-01734-0. Epub ahead of print. PMID: 37160847.

137. Lopez MA, Yu X, Hetrick R, Raman S, Lee J, Hall J, Tran K, Vonasek B, Garg A, Raphael J, Bocchini C. Social Needs Screening in Hospitalized Pediatric Patients: A Randomized Controlled Trial. Hosp Pediatr. 2023 Feb 1;13(2):95-114. doi: 10.1542/hpeds.2022-006815. PMID: 36594231. 138. Macedo DM, Reilly JA, Pettit S, Negoita C, Ruth L, Cox ED, Staugas R, Procter N. Trauma-informed mental health practice during COVID-19: Reflections from a Community of Practice initiative. Int J Ment Health Nurs. 2022 Aug;31(4):1021-1029. doi: 10.1111/inm.13013. Epub 2022 May 16. PMID: 35574711 Review. 139. Maltman N, DaWalt LS, Hong J, Baker MW, Berry-Kravis EM, Brilliant MH, Mailick M. FMR1 CGG Repeats and Stress Influence SelfReported Cognitive Functioning in Mothers. Am J Intellect Dev Disabil. 2023 Jan 1;128(1):120. doi: 10.1352/1944-7558-128.1.1. PMID: 36548377. 140. Mann EA, Rompicherla S, Gallagher MP, Alonso GT, Fogel NR, Simmons J, Wood JR, Wong JC, Noor N, Gomez P, Daniels M, Ebekozien O. Comorbidities increase COVID-19 hospitalization in young people with type 1 diabetes. Pediatr Diabetes. 2022 Nov;23(7):968-975. doi: 10.1111/pedi.13402. Epub 2022 Aug 28. PMID: 36054578; PMCID: PMC9538459. 141. Marshall GS, Abbing-Karahagopian V, Marshall HS, Cenci S, Conway JH, Occhipinti E, Bekkat-Berkani R, Banzhoff A, Sohn WY. A comprehensive review of clinical and real-world safety data for the four-component serogroup B meningococcal vaccine (4CMenB). Expert Rev Vaccines. 2023 Jan-Dec;22(1):530-544. doi: 10.1080/14760584.2023.2222015. Review. PMID: 37278390.

pediatrics.wisc.edu

PUBLICATIONS

142. Marten KA, Allen DB, Rehm J, Vanderwall C, Peterson AL, Carrel AL. A Multidisciplinary Approach to Pediatric Obesity Shows Improvement Postintervention. Acad Pediatr. 2022 Oct 29:S1876-2859(22)00556-3. doi: 10.1016/j.acap.2022.10.019. Epub ahead of print. PMID: 36441091. 143. Matharu PK, Held PK, Allen DB. Multiple 17-OHP Cutoff Co-Variates Fail to Improve 21-Hydroxylase Deficiency Screening Accuracy. Int J Neonatal Screen. 2022 Oct 25;8(4):57. doi: 10.3390/ijns8040057. PMID: 36412583. 144. Mathur M, Robiolio H, Ebert L, Kerr BR. Family stress during the COVID-19 pandemic: A qualitative analysis. BMJ open. 2023 May. doi: 10.1136/bmjopen-2022-061396. 145. McAdams RM. Artist’s Statement: Seeking Asylum. Acad Med. 2022 Oct 1;97(10):1437. doi: 10.1097/ACM.0000000000004841. Epub 2022 Sep 23. PMID: 36198156. 146. McAdams RM. Family-flustered care: a case against jargon in the NICU. Pediatr Res. 2022 Aug 30. doi: 10.1038/s41390-022-02285-4. Epub ahead of print. PMID: 36042328. 147. McAdams RM. The Gift of Human Milk. J Hum Lact. 2023 Feb;39(1):13. doi: 10.1177/08903344221148542. PMID: 36779648. 148. McCauley KE, Rackaityte E, LaMere B, Fadrosh DW, Fujimura KE, Panzer AR, Lin DL, Lynch KV, Halkias J, Mendoza VF, Burt TD, Bendixsen C, Barnes K, Kim H, Jones K, Ownby DR, Johnson CC, Seroogy CM, Gern JE, Boushey HA, Lynch SV; ECHO Children’s Respiratory and Environmental Workgroup. Heritable vaginal bacteria influence immune tolerance and relate to early-life markers of allergic sensitization in infancy. Cell Rep Med. 2022 Aug 16;3(8):100713. doi: 10.1016/j.xcrm.2022.100713. Epub 2022 Aug 6. PMID: 35932762.

149. McCulley DJ, Jensen EA, Sucre JMS, McKenna S, Sherlock LG, Dobrinskikh E, Wright CJ. Racing against time: leveraging preclinical models to understand pulmonary susceptibility to perinatal acetaminophen exposures. Am J Physiol Lung Cell Mol Physiol. 2022 Jul 1;323(1):L1-L13. doi: 10.1152/ ajplung.00080.2022. Epub 2022 May 3. PMID: 35503238; PMCID: PMC9208439. 150. McGarry ME, Ren CL, Wu R, Farrell PM, McColley SA. Detection of diseasecausing CFTR variants in state newborn screening programs. Pediatr Pulmonol. 2023 Feb;58(2):465-474. doi: 10.1002/ppul.26209. Epub 2022 Oct 25. PMID: 36237137; PMCID: PMC9870974. 151.

McIlwain SJ, Hoefges A, Erbe AK, Sondel PM, Ong IM. Ranking Antibody Binding Epitopes and Proteins Across Samples from Whole Proteome Tiled Linear Peptides. bioRxiv. 2023 Apr 25;. doi: 10.1101/2023.04.23.536620. PMID: 37162956; PMCID: PMC10168206.

152. McIntyre A, Caulum A, Cox A, Sanchez D, Sampson H, Baker MG, Singh AM. Food protein-induced enterocolitis syndrome (FPIES) after multiple tolerant ingestions. J Allergy Clin Immunol Pract. 2023 Jan;11(1):324-325. doi: 10.1016/j.jaip.2022.07.004. Epub 2022 Jul 19. PMID: 35868451. 153. McMinn PH, Ahmed A, Huttenlocher A, Beebe DJ, Kerr SC. The lymphatic endotheliumderived follistatin: activin A axis regulates neutrophil motility in response to Pseudomonas aeruginosa. Integr Biol (Camb). 2023 Feb 13:zyad003. doi: 10.1093/intbio/zyad003. Epub ahead of print. PMID: 36781971. 154. Menda N, Edwards E. Measuring Equity for Quality Improvement. Clin Perinatol. 2023 Jun;50(2):531-543. doi: 10.1016/j. clp.2023.01.010. Epub 2023 Mar 21. Review. PMID: 37201995.

University of Wisconsin Department of Pediatrics | Annual Report 2023

PUBLICATIONS

155. Mercer AN, Mauskar S, Baird J, Berry J, Chieco D, Copp K, Cox ED, Haskell H, Hennessy K, Kelly MM, Mallick N, McGeachey A, Melvin P, Ngo T, Pinkham A, Rogers J, Wickremasinghe W, Williams D, Landrigan CP, Khan A. Family Safety Reporting in Hospitalized Children With Medical Complexity. Pediatrics. 2022 Jul 6:e2021055098. doi: 10.1542/peds.2021055098. Online ahead of print. PMID: 35791784. 156. Meza K, Vasquez-Loarte T, Rodriguez-Alarcon F, San Roman O, Rojas-Camayo J, Mejia CR, Medina M, Zapata HA, Saarinen A, BravoJaimes K. Critical congenital heart disease detection in the ANDES: Challenges and opportunities. Int J Cardiology Congenital Heart Dis. 2022 Dec. 157. Miller RL, Schuh H, Chandran A, Aris IM, Bendixsen C, Blossom J, Breton C, Camargo CA Jr, Canino G, Carroll KN, Commodore S, Cordero JF, Dabelea DM, Ferrara A, Fry RC, Ganiban JM, Gern JE, Gilliland FD, Gold DR, Habre R, Hare ME, Harte RN, Hartert T, Hasegawa K, Khurana Hershey GK, Jackson DJ, Joseph C, Kerver JM, Kim H, Litonjua AA, Marsit CJ, McEvoy C, Mendonça EA, Moore PE, Nkoy FL, O’Connor TG, Oken E, Ownby D, Perzanowski M, Rivera-Spoljaric K, Ryan PH, Singh AM, Stanford JB, Wright RJ, Wright RO, Zanobetti A, Zoratti E, Johnson CC; program collaborators for Environmental influences on Child Health Outcomes. Incidence Rates of Childhood Asthma with Recurrent Exacerbations in the U.S. Environmental influences on Child Health Outcomes (ECHO) Program. J Allergy Clin Immunol. 2023 Mar 25:S0091-6749(23)00368-8. doi: 10.1016/j. jaci.2023.03.016. Epub ahead of print. PMID: 36972767.

159. Moody JF, Dean DC 3rd, Kecskemeti SR, Blennow K, Zetterberg H, Kollmorgen G, Suridjan I, Wild N, Carlsson CM, Johnson SC, Alexander AL, Bendlin BB. Associations between diffusion MRI microstructure and cerebrospinal fluid markers of Alzheimer’s disease pathology and neurodegeneration along the Alzheimer’s disease continuum. Alzheimers Dement (Amst). 2022 Dec 4;14(1):e12381. doi: 10.1002/dad2.12381. PMID: 36479018; PMCID: PMC9720004. 160. Moreno MA, French B, Christakis DA. Call for Papers on Adolescent Mental Health. JAMA Pediatr. 2023 Jan 23. doi: 10.1001/ jamapediatrics.2022.5540. Epub ahead of print. PMID: 36689238. 161. Moreno MA, Kerr B, Fairlie AM, Lewis M. Feasibility and Acceptability of the Social Media-Brief Alcohol Screening and Intervention for College Students Intervention. J Adolesc Health. 2023 Mar 3:S1054-139X(23)00061-7. doi: 10.1016/j.jadohealth.2023.01.014. Epub ahead of print. PMID: 36872115. 162. Moreno MA, Radesky J. Putting Forward a New Narrative for Adolescent Media: The American Academy of Pediatrics Center of Excellence on Social Media and Youth Mental Health. J Adolesc Health. 2023 May 23;. doi: 10.1016/j. jadohealth.2023.04.027. [Epub ahead of print] PubMed PMID: 37227337. 163. Moreno MA. Concerning Trends in Youth E-Cigarette and Cannabis Use: Dual Use and Social Media Marketing — A Commentary on Roberts et al. (2022). J Stud Alcohol Drugs. 2022 Sep;83(5):773-774. PMID: 36136450

158. Minichiello V, Webber S. Resident Physician Perspectives on Mindfulness Education in Residency: A Multispecialty Qualitative Assessment of Clinical Care Impact. J Grad Med Educ. 2023 Jun;15(3):356-364. doi: 10.4300/JGME-D-22-00492.1. Epub 2023 Jun 14. PMID: 37363667; PMCID: PMC10286909. pediatrics.wisc.edu

PUBLICATIONS

164. Morin A, Thompson EE, Helling BA, ShoreyKendrick LE, Faber P, Gebretsadik T, Bacharier LB, Kattan M, O’Connor GT, Rivera-Spoljaric K, Wood RA, Barnes KC, Mathias RA, Altman MC, Hansen K, McEvoy CT, Spindel ER, Hartert T, Jackson DJ, Gern JE, McKennan CG, Ober C; program collaborators for Environmental Influences on Child Health Outcomes and Children’s Respiratory and Environmental Workgroup. A Functional Genomics Pipeline to Identify High-Value Asthma and Allergy CpGs in the Human Methylome. J Allergy Clin Immunol. 2023 Feb 6:S0091-6749(23)00149-5. doi: 10.1016/j.jaci.2022.12.828. Epub ahead of print. PMID: 36754293. 165. Mueller KP, Piscopo NJ, Forsberg MH, Saraspe LA, Das A, Russell B, Smerchansky M, Cappabianca D, Shi L, Shankar K, Sarko L, Khajanchi N, La Vonne Denne N, Ramamurthy A, Ali A, Lazzarotto CR, Tsai SQ, Capitini CM, Saha K. Production and characterization of virus-free, CRISPR-CAR T cells capable of inducing solid tumor regression. J Immunother Cancer. 2022 Sep;10(9). doi: 10.1136/jitc2021-004446. PMID: 36382633; PMCID: PMC9454086. 166. Munjal NK, Clark RSB, Simon DW, Kochanek PM and Horvat CM. Interoperable and explainable machine learning models to predict morbidity and mortality in acute neurological injury in the pediatric intensive care unit: secondary analysis of the TOPICC study. Front. Pediatr. 2023; 11:1177470. doi: 10.3389/ fped.2023.1177470 167. Munjal NK, Fleischman AD, Coller RJ. Machine Learning, Predicting Future Hospitalizations, and the Importance of Perception. Hosp Pediatr. 2023 May 1;13(5):e114-e116. doi: 10.1542/ hpeds.2023-007224. PMID: 37092274.

168. Murguia-Favela L, Suresh S, Wright NAM, Alvi S, Tehseen S, Hernandez-Trujillo V, Seroogy CM, Haddad E, Nieves D, Walter JE, Pettiford L, Kamani NR, Keller MD, PhamHuy A, Grunebaum E. Long-Term Immune Reconstitution in ADA-Deficient Patients Treated With Elapegademase: A Real-World Experience. J Allergy Clin Immunol Pract. 2023 Feb 1:S2213-2198(23)00114-9. doi: 10.1016/j. jaip.2023.01.028. Epub ahead of print. PMID: 36736953. 169. Nackers K, Tatar R, Cowan E, Zakowski L, Stewart K, Ahrens S, Jacques L, Chheda S. First, do no harm: impact of the transition to an integrated curriculum on medical knowledge acquisition of the transitional cohort. Med Educ Online. 2022 Dec;27(1):2007561. doi: 10.1080/10872981.2021.2007561. PMID: 34813397; PMCID: PMC8635576. 170. Nahm NJ, Mackenzie WGS, Mackenzie WG, Gough E, Hashmi SS, Hecht JT, Legare JM, Little ME, Modaff P, Pauli RM, RodriguezBuritica DF, Serna ME, Smid CJ, Hoover-Fong J, Bober MB. Achondroplasia natural history study (CLARITY): 60-year experience in orthopedic surgery from four skeletal dysplasia centers. Orphanet J Rare Dis. 2023 Jun 6;18(1):139. doi: 10.1186/s13023-023-02738-x. PMID: 37280669; PMCID: PMC10246371 171.

Nair AK, Van Hulle CA, Bendlin BB, Zetterberg H, Blennow K, Wild N, Kollmorgen G, Suridjan I, Busse WW, Dean DC 3rd, Rosenkranz MA. Impact of asthma on the brain: evidence from diffusion MRI, CSF biomarkers and cognitive decline. Brain Commun. 2023;5(3):fcad180. doi: 10.1093/braincomms/fcad180. eCollection 2023. PMID: 37377978; PMCID: PMC10292933.

172. Nemanich ST, Gillick BT, Sukal-Moulton T, Ahamed SI. Can Technology Improve Participation From Underserved Children and Families in Rehabilitation Research? WMJ. 2022 Oct;121(3):174-176. PMID: 36301641.

University of Wisconsin Department of Pediatrics | Annual Report 2023

PUBLICATIONS

173. Noor N, Norman G, Sonabend R, Chao L, Kamboj M, Golden L, Bekx MT, Hseih S, Levy C, Sanchez J, Rapaport R, Ebekozien O. An Observational Crossover Study of People Using Real-Time Continuous Glucose Monitors Versus Self-Monitoring of Blood Glucose: Real-World Evidence Using EMR Data From More Than 12,000 People With Type 1 Diabetes. J Diabetes Sci Technol. 2023 Jun 1;:19322968231178017. doi: 10.1177/19322968231178017. [Epub ahead of print] PMID: 37264642. 174. Numata M, Sajuthi S, Bochkov YA, Loeffler J, Everman J, Vladar EK, Cooney RA, Reinhardt RL, Liu AH, Seibold MA, Voelker DR. Anionic Pulmonary Surfactant Lipid Treatment Inhibits Rhinovirus A Infection of the Human Airway Epithelium. Viruses. 2023 Mar 14;15(3):747. doi: 10.3390/v15030747. PMID: 36992456; PMCID: PMC10055697. 175. Oken E, Bastain TM, Bornkamp N, Breton CV, Fry RC, Gold DR, Hivert MF, Howland S, Jackson DJ, Johnson CC, Jones K, Killingbeck M, O’Shea TM, Ortega M, Ownby D, Perera F, Rollins JV, Herbstman JB; program collaborators for Environmental influences on Child Health Outcomes. When a birth cohort grows up: challenges and opportunities in longitudinal developmental origins of health and disease (DOHaD) research. J Dev Orig Health Dis. 2023 Apr;14(2):175-181. doi: 10.1017/ S2040174422000629. Epub 2022 Nov 21. PMID: 36408681; PMCID: PMC9998333. 176. Ozaydin B, Bicki E, Taparli OE, Sheikh TZ, Schmidt DK, Yapici S, Hackett MB, Karahan-Keles N, Eickhoff JC, Corcoran K, Lagoa-Miguel C, Guerrero Gonzalez J, Dean Iii DC, Sousa AMM, Ferrazzano PA, Levine JE, Cengiz P. Novel injury scoring tool for assessing brain injury following neonatal hypoxia-ischemia in mice. Dev Neurosci. 2022 May 25. doi: 10.1159/000525244. Epub ahead of print. PMID: 35613558.

177. Padilla EP, Voelz K, Kille T. A Unique Presentation of Multicentric Myofibromatosis in the Masseter Muscle of a Pediatric Patient. Ear Nose Throat J. 2022 Sep 9:1455613221125933. doi: 10.1177/01455613221125933. Epub ahead of print. PMID: 36085035. 178. Paloian NJ, Nemeth B, Sharafinski M, Modaff P, Steiner RD. Real-world effectiveness of burosumab in children with X-linked hypophosphatemic rickets. PediatrNephrol. 2022 Nov;37(11):2667-2677. doi: 10.1007/ s00467-022-05484-7. Epub 2022 Feb 24. PMID: 35211790. 179. Papadas A, Deb G, Cicala A, Officer A, Hope C, Pagenkopf A, Flietner E, Morrow ZT, Emmerich P, Wiesner J, Arauz G, Bansal V, Esbona K, Capitini CM, Matkowskyj KA, Deming DA, Politi K, Abrams SI, Harismendy O, Asimakopoulos F. Stromal remodeling regulates dendritic cell abundance and activity in the tumor microenvironment. Cell Rep. 2022 Aug 16;40(7):111201. doi: 10.1016/j.celrep.2022.111201. PMID: 35977482; PMCID: PMC9402878. 180. Papi A, Corren J, Castro M, Domingo C, Rogers L, Chapman KR, Jackson DJ, Daizadeh N, Pandit-Abid N, Gall R, Jacob-Nara JA, Rowe PJ, Deniz Y, Ortiz B. Dupilumab reduced impact of severe exacerbations on lung function in patients with moderate-to-severe type 2 asthma. Allergy. 2022 Jul 28. doi: 10.1111/all.15456. Epub ahead of print. PMID: 35899469. 181. Pascual-Pasto G, McIntyre B, Shraim R, Buongervino SN, Erbe AK, Zhelev DV, Sadirova S, Giudice AM, Martinez D, Garcia-Gerique L, Dimitrov DS, Sondel PM, Bosse KR. GPC2 antibody-drug conjugate reprograms the neuroblastoma immune milieu to enhance macrophage-driven therapies. J Immunother Cancer. 2022 Dec;10(12):e004704. doi: 10.1136/ jitc-2022-004704. PMID: 36460335; PMCID: PMC9723962.

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PUBLICATIONS

182. Patankar S, Cruz AT, Douglas-Jones B, GarciaPrats AJ, Kay A, Reuter A, Schaaf HS, Seddon JA, Sharma S, Starke J, Tommasi M, Triasih R, Furin JJ. Making the Case for All-Oral, Shorter Regimens for Children with Drug-Resistant Tuberculosis. Am J Respir Crit Care Med. 2023 Jun 5;. doi: 10.1164/rccm.202304-0670VP. [Epub ahead of print] PMID: 37276531. 183. Peters ME, Strayer J, Wald ER. Serious Infusion Reactions in Two Adolescents Receiving Bebtelovimab. Pediatr Infect Dis J. 2023 Jan 1;42(1):e1-e3. doi: 10.1097/ INF.0000000000003743. Epub 2022 Nov 22. PMID: 36476524; PMCID: PMC9725739. 184. Phelan KJ, Dill-McFarland KA, Kothari A, Segnitz RM, Burkle J, Grashel B, Jenkins S, Spagna D, Martin LJ, Haslam DB, Biagini JM, Kalra M, McCoy KS, Ross KR, Jackson DJ, Mersha T, Altman MC, Hershey GKK. Airway Transcriptome Networks Identify Susceptibility to Frequent Asthma Exacerbations in Children. J Allergy Clin Immunol. 2023 Mar 12:S0091-6749(23)00292-0. doi: 10.1016/j. jaci.2023.02.031. Epub ahead of print. PMID: 36918038. 185. Pieper AA, Spiegelman DV, Felder MAR, Feils AS, Tsarovsky NW, Zaborek J, Morris ZS, Erbe AK, Rakhmilevich AL, Sondel PM. Factors impacting the efficacy of the in-situ vaccine with CpG and OX40 agonist. Cancer Immunol Immunother. 2023 Jul;72(7):24592471. doi: 10.1007/s00262-023-03433-3. Epub 2023 Apr 5. PMID: 37016127; PMCID: PMC10264285. 186. Planalp EM, Dowe KN, Alexander AL, Goldsmith HH, Davidson RJ, Dean DC 3rd. White matter microstructure predicts individual differences in infant fear (But not anger and sadness). Dev Sci. 2022 Nov 11:e13340. doi: 10.1111/desc.13340. Epub ahead of print. PMID: 36367143.

187. Pramparo T, Steiner RD, Rodems S, Jenkinson C. Allelic prevalence and geographic distribution of cerebrotendinous xanthomatosis. Orphanet J Rare Dis. 2023 Jan 17;18(1):13. doi: 10.1186/s13023-022-02578-1. PMID: 36650582; PMCID: PMC9843874. 188. Prasun P, Evans A, Cork E, Houten SM, Webb BD. A novel deleterious ETFA promoter variant causative of multiple acyl-CoA dehydrogenase deficiency. Am J Med Genet A. 2023 Apr;191(4):1089-1093. Doi: 10.1002/ ajmg.a.63104. Epub 2022 Dec 28. PMID: 36579410. 189. Prigge MBD, Bigler ED, Lange N, Morgan J, Froehlich A, Freeman A, Kellett K, Kane KL, King CK, Taylor J, Dean DC 3rd, King JB, Anderson JS, Zielinski BA, Alexander AL, Lainhart JE. Longitudinal Stability of Intellectual Functioning in Autism Spectrum Disorder: From Age 3 Through Mid-adulthood. J Autism Dev Disord. 2022 Oct;52(10):4490-4504. doi: 10.1007/ s10803-021-05227-x. Epub 2021 Oct 22. PMID: 34677753; PMCID: PMC9090201. 190. Rabinovitch N, Nevid M, Lomas C, Covar R, Levy H, Leung DYM. Reversible peripheral airway obstruction and lung hyperinflation in children presenting with dyspnea and exercise intolerance after COVID-19 infection. J Allergy Clin Immunol Pract. 2022 Oct;10(10):27482749.e1. doi: 10.1016/j.jaip.2022.07.038. Epub 2022 Sep 29. PMID: 36184531; PMCID: PMC9520121. 191. Raina R, Shah R, Marks SD, Johnson JN, Nied M, Bhatt GC, Bonham CA, Datla N, Sethi SK, Bartosh SM. The effects of COVID-19 on pediatric and adult solid organ transplant recipients and the emergence of telehealth. Pediatr Transplant. 2023 Jun;27(4):e14490. doi: 10.1111/petr.14490. Epub 2023 Mar 6. PMID: 36879358.

University of Wisconsin Department of Pediatrics | Annual Report 2023

PUBLICATIONS

192. Raita Y, Pérez-Losada M, Freishtat RJ, Hahn A, Castro-Nallar E, Ramos-Tapia I, Stearrett N, Bochkov YA, Gern JE, Mansbach JM, Zhu Z, Camargo CA, Hasegawa K. Nasopharyngeal metatranscriptome profiles of infants with bronchiolitis and risk of childhood asthma: a multicentre prospective study. Eur Respir J. 2022 Jul 13;60(1):2102293. doi: 10.1183/13993003.02293-2021. PMID: 34916264; PMCID: PMC9206513. 193. Rasnick E, Ryan P, Blossom J, LuttmannGibson H, Lothrop N, Habre R, Gold DR, Vancil A, Schwartz J, Gern JE, Brokamp C. High Resolution and Spatiotemporal Place-Based Computable Exposures at Scale. AMIA Jt Summits Transl Sci Proc. 2023 Jun 16;2023:6270. PMID: 37350915; PMCID: PMC10283107. 194. Rehani MR, Marcus MS, Harris AB, Farrell PM, Ren CL. Variation in cystic fibrosis newborn screening algorithms in the United States. Pediatr Pulmonol. 2023 Mar;58(3):927-933. doi: 10.1002/ppul.26279. Epub 2022 Dec 16. PMID: 36507555. 195. Rinella SP, Bell HC, Turicek DP, Shi L, Hoang NM, Rui L, Hess NJ, Capitini CM. Combinatorial fedratinib and venetoclax treatment is effective on human B cell acute lymphoblastic leukemia with high Flt3 expression. bioRxiv. 2023 Jun 9;. doi: 10.1101/2023.06.07.544058. PMID: 37333339; PMCID: PMC10274796. 196. Rizner JD, Bartlett HL, Shaw RE. New-Onset Accelerated Idioventricular Rhythm During Dental Rehabilitation. Anesth Prog. 2022 Dec 1;69(4):32-36. doi: 10.2344/anpr-69-02-13. PMID: 36534779; PMCID: PMC9773410.

197. Robertson TF, Hou Y, Schrope J, Shen S, Rindy J, Sauer JD, Dinh HQ, Huttenlocher A. A tessellated lymphoid network provides whole-body T cell surveillance in zebrafish. Proc Natl Acad Sci U S A. 2023 May 16;120(20):e2301137120. doi: 10.1073/ pnas.2301137120. Epub 2023 May 8. PMID: 37155881; PMCID: PMC10193988. 198. Robertson TF, Hou Y, Shen S, Rindy J, Sauer JD, Dinh HQ, Huttenlocher A. A tessellated lymphoid network provides whole-body T cell surveillance in zebrafish. bioRxiv. 2023 Jan 19;. doi: 10.1101/2023.01.17.524414. PubMed PMID: 36711463; PMCID: PMC9882119. 199. Rock MJ, Baker M, Antos N, Farrell PM. Refinement of newborn screening for cystic fibrosis with next generation sequencing. Pediatr Pulmonol. 2023 Mar;58(3):778-787. doi: 10.1002/ppul.26253. Epub 2022 Dec 5. PMID: 36416003. 200. Rossler KJ, de Lange WJ, Mann MW, Aballo TJ, Melby JA, Zhang J, Kim G, Bayne EF, Zhu Y, Farrell ET, Kamp TJ, Ralphe JC, Ge Y. Lactate and Immunomagnetic-purified iPSCderived Cardiomyocytes Generate Comparable Engineered Cardiac Tissue Constructs. bioRxiv [Preprint]. 2023 May 6:2023.05.05.539642. doi: 10.1101/2023.05.05.539642. PMID: 37205556; PMCID: PMC10187273. 201. Salamzade R, Cheong JZA, Sandstrom S, Swaney MH, Stubbendieck RM, Starr NL, Currie CR, Singh AM, Kalan LR. Evolutionary investigations of the biosynthetic diversity in the skin microbiome using lsaBGC. Microb Genom. 2023 Apr;9(4):mgen000988. doi: 10.1099/mgen.0.000988. PMID: 37115189; PMCID: PMC10210951.

pediatrics.wisc.edu

PUBLICATIONS

202. Samimi K, Desa DE, Lin W, Weiss K, Li J, Huisken J, Miskolci V, Huttenlocher A, Chacko JV, Velten A, Rogers JD, Eliceiri KW, Skala MC. Light-sheet autofluorescence lifetime imaging with a single-photon avalanche diode array. J Biomed Opt. 2023 Jun;28(6):066502. doi: 10.1117/1.JBO.28.6.066502. Epub 2023 Jun 21. PMID: 37351197; PMCID: PMC10284079. 203. Samimi K, Desa DE, Lin W, Weiss K, Li J, Huisken J, Miskolci V, Huttenlocher A, Chacko JV, Velten A, Rogers JD, Eliceiri KW, Skala MC. Light sheet autofluorescence lifetime imaging with a single photon avalanche diode array. bioRxiv. 2023 Feb 3;. doi: 10.1101/2023.02.01.526695. PMID: 36778488; PMCID: PMC9915663. 204. Samuel AM, Hacker LL, Zebracki J, Bogenschutz MC, Schulz L, Strayer J, Vanderloo JP, Cengiz P, Henderson S. Remdesivir Use in Pediatric Patients for SARS-CoV-2 Treatment: Single Academic Center Study. Pediatr Infect Dis J. 2023 Apr 1;42(4):310-314. doi: 10.1097/ INF.0000000000003814. Epub 2022 Dec 29. PMID: 36728726; PMCID: PMC9990481. 205. Sandri BJ, Kim J, Lubach GR, Lock EF, Guerrero C, Higgins L, Markowski TW, Kling PJ, Georgieff MK, Coe CL, Rao RB. Tandem mass tag proteomic and untargeted metabolomic profiling reveals altered serum and CSF biochemical datasets in iron deficient monkeys. Data Brief. 2022 Sep 11;45:108591. doi: 10.1016/j. dib.2022.108591. PMID: 36164307; PMCID: PMC9508431.

206. Santoro J, Spinazzi N, Filipink R, Hayati-Rezvan P, Kammeyer R, Patel L, Sannar E, Dwyer L, Banerjee A, Khoshnood M, Jafarpour S, Boyd N, Partridge R, Gombolay G, Christy A, de Asua DR, Ortega MDC, Manning M, Mater HV, Worley G, Franklin C, Stanley M, Brown R, Capone G, Quinn E, Rafii M. Immunotherapy Responsiveness and Risk of Relapse in Down Syndrome Regression Disorder. Res Sq [Preprint]. 2023 Feb 13:rs.3.rs-2521595. doi: 10.21203/rs.3.rs-2521595/v1. PMID: 36824719; PMCID: PMC9949176. 207. Santoro JD, Patel L, Kammeyer R, Filipink RA, Gombolay GY, Cardinale KM, Real de Asua D, Zaman S, Santoro SL, Marzouk SM, Khoshnood M, Vogel BN, Tanna R, Pagarkar D, Dhanani S, Ortega MDC, Partridge R, Stanley MA, Sanders JS, Christy A, Sannar EM, Brown R, McCormick AA, Van Mater H, Franklin C, Worley G, Quinn EA, Capone GT, Chicoine B, Skotko BG, Rafii MS. Assessment and Diagnosis of Down Syndrome Regression Disorder: International Expert Consensus. Front Neurol. 2022 Jul 15;13:940175. doi: 10.3389/ fneur.2022.940175. PMID: 35911905; PMCID: PMC9335003. 208. Schefelker J, Zhang X, Dodge A, Marten K, Dimailig G, Bartlett HL, Peterson AL. Impact of the COVID-19 pandemic on cardiometabolic health parameters in children with preexisting dyslipidemia. J Clin Lipidol. 2022 Sep-Oct;16(5):643-648. doi: 10.1016/j. jacl.2022.06.006. Epub 2022 Jun 24. PMID: 35798651; PMCID: PMC9232258. 209. Schiariti V, de Campos AC, Sudati IP, Seal AK, Springer PE, Thomson H, Wamithi S, Wei G, Spittle A, Gillick BT. Global COVID-19 childhood disability data coordination: A collaborative initiative of the international alliance of academies of childhood disability. J Pediatr Rehabil Med. 2023 Feb 18. doi: 10.3233/ PRM-220035. Epub ahead of print. PMID: 36847026.

University of Wisconsin Department of Pediatrics | Annual Report 2023

PUBLICATIONS

210. Schmit KM, DeMuri GP, Eickhoff JC, Bochkov Y, Gern JE, Wald ER. Genotypic Diversity of Childhood Rhinovirus Infections. J Pediatric Infect Dis Soc. 2023 Apr 28;12(4):239241. doi: 10.1093/jpids/piad018. PMID: 37013688; PMCID: PMC10146928. 211.

Schmitz RL, Tweed KE, Rehani P, Samimi K, Riendeau J, Jones I, Maly EM, Guzman EC, Forsberg MH, Shahi A, Capitini CM, Walsh AJ, Skala MC. Autofluorescence lifetime imaging classifies human lymphocyte activation and subtype. bioRxiv. 2023 Jan 23;. doi: 10.1101/2023.01.23.525260. PMID: 36747690; PMCID: PMC9900834.

212. Schoen TJ, Calise DG, Bok JW, Giese MA, Nwagwu CD, Zarnowski R, Andes D, Huttenlocher A, Keller NP. Aspergillus fumigatus transcription factor ZfpA regulates hyphal development and alters susceptibility to antifungals and neutrophil killing during infection. PLoS Pathog. 2023 May 1;19(5):e1011152. doi: 10.1371/journal.ppat.1011152. PMID: 37126504; PMCID: PMC10174577 213. Schoen TJ, Calise DG, Bok JW, Nwagwu CD, Zarnowski R, Andes D, Huttenlocher A, Keller NP. Aspergillus fumigatus transcription factor ZfpA regulates hyphal development and alters susceptibility to antifungals and neutrophil killing during infection. bioRxiv. 2023 Jan 26;. doi: 10.1101/2023.01.25.525624. PMID: 36747761; PMCID: PMC9901008. 214. Schrope JH, Huttenlocher A. The cell’s dilemma: resolving directional decisions. Trends Immunol. 2023 May;44(5):324-325. doi: 10.1016/j.it.2023.03.011. Epub 2023 Apr 6. PMID: 37029072.

215. Sertori R, Lin JX, Martinez E, Rana S, Sharo A, Kazemian M, Sunderam U, Andrake M, Shinton S, Truong B, Dunbrack RM, Liu C, Srinivasan R, Brenner SE, Seroogy CM, Puck JM, Leonard WJ, Wiest DL. Investigation of the causal etiology in a patient with T-B+NK+ immunodeficiency. Front Immunol. 2022 Jul 29;13:928252. doi: 10.3389/ fimmu.2022.928252. PMID: 35967429; PMCID: PMC9372720. 216. Shin HC, Bochkov YA, Kim K, Gern JE, Jarjour NN, Esnault S. A motif in the 5’untranslated region of messenger RNAs regulates protein synthesis in a S6 kinase-dependent manner. Adv Biol Regul. 2023 Jun 7;89:100975. doi: 10.1016/j.jbior.2023.100975. Epub ahead of print. PMID: 37302177. 217. Shipp CL, Gergen PJ, Gern JE, Matsui EC, Guilbert TW. Asthma Management in Children. J Allergy Clin Immunol Pract. 2023 Jan;11(1):918. doi: 10.1016/j.jaip.2022.10.031. Epub 2022 Nov 9. PMID: 36334702. 218. Sidbury R, Alikhan A, Bercovitch L, Cohen DE, Darr JM, Drucker AM, Eichenfield LF, Frazer-Green L, Paller AS, Schwarzenberger K, Silverberg JI, Singh AM, Wu PA, Davis DMR. Executive Summary: American Academy of Dermatology Guidelines of care for the management of atopic dermatitis in adults with topical therapies. J Am Acad Dermatol. 2023 Jan 6:S0190-9622(23)00056-7. doi: 10.1016/j. jaad.2022.08.068. Epub ahead of print. PMID: 36623556. 219. Sidbury R, Alikhan A, Bercovitch L, Cohen DE, Darr JM, Drucker AM, Eichenfield LF, Frazer-Green L, Paller AS, Schwarzenberger K, Silverberg JI, Singh AM, Wu PA, Davis DMR. Guidelines of care for the management of atopic dermatitis in adults with topical therapies. J Am Acad Dermatol. 2023 Jan 11:S0190-9622(23)00004-X. doi: 10.1016/j. jaad.2022.12.029. Epub ahead of print. PMID: 36641009.

pediatrics.wisc.edu

PUBLICATIONS

220. Siegfried EC, Arkin LM, Chiu YE, Hebert AA, Callen JP, Castelo-Soccio L, Co DO, Cordoro KM, Curran ML, Dalrymple AM, Flohr C, Gordon KB, Hanna D, Irvine AD, Kim S, Kirkorian AY, Lara-Corrales I, Lindstrom J, Paller AS, Reyes M, Begolka WS, Tom WL, Van Voorhees AS, Vleugels RA, Lee LW, Davies OMT, BrandlingBennett HA. Methotrexate for inflammatory skin disease in pediatric patients: Consensus treatment guidelines. Pediatr Dermatol. 2023 Jun 14. doi: 10.1111/pde.15327. Epub ahead of print. PMID: 37316462. 221. Simpson EA, Saiote C, Sutter E, Lench DH, Ikonomidou C, Villegas MA, Gillick BT. Remotely monitored transcranial direct current stimulation in pediatric cerebral palsy: open label trial protocol. BMC Pediatr. 2022 Sep 29;22(1):566. doi: 10.1186/s12887-022-03612-8. PMID: 36175848; PMCID: PMC9521558. 222. Singh AM, Rubiera-Pebe R, Ahmad Y, Shafique M, Hicks JK, Tanvetyanon T. Safety Monitoring Activity During EGFR or Anaplastic Lymphoma Kinase Inhibitor Therapy for Patients With Lung Cancer. JCO Oncol Pract. 2023 Jun;19(6):345351. doi: 10.1200/OP.22.00787. Epub 2023 Apr 19. PMID: 37075260. 223. Sinha P, Gabor R, Haupt-Harrington R, Deering L, Steiner RD. Dental manifestations in adult hypophosphatasia and their correlation with biomarkers. JIMD Rep. 2022 Jun 28;63(5):434445. doi: 10.1002/jmd2.12307. PMID: 36101824; PMCID: PMC9458606. 224. Snyder BM, Gebretsadik T, Rohrig NB, Wu P, Dupont WD, Dabelea DM, Fry RC, Lynch SV, McEvoy CT, Paneth NS, Ryckman KK, Gern JE, Hartert TV, On Behalf Of Program Collaborators For Environmental Influences On Child Health Outcomes. The Associations of Maternal Health Characteristics, Newborn Metabolite Concentrations, and Child Body Mass Index among US Children in the ECHO Program. Metabolites. 2023 Apr 1;13(4):510. doi: 10.3390/metabo13040510. PMID: 37110168; PMCID: PMC10144800.

225. Song YS, Annalora AJ, Marcus CB, Jefcoate CR, Sorenson CM, Sheibani N. Cytochrome P450 1B1: A Key Regulator of Ocular Iron Homeostasis and Oxidative Stress. Cells. 2022 Sep 20;11(19):2930. doi: 10.3390/cells11192930. PMID: 36230892. 226. Song YS, Jamali N, Sorenson CM, Sheibani N. Vitamin D Receptor Expression Limits the Angiogenic and Inflammatory Properties of Retinal Endothelial Cells. Cells. 2023 Jan 16;12(2):335. doi: 10.3390/cells12020335. PMID: 36672270; PMCID: PMC9856450. 227. Song YS, Zaitoun IS, Wang S, Darjatmoko SR, Sorenson CM, Sheibani N. Cytochrome P450 1B1 Expression Regulates Intracellular Iron Levels and Oxidative Stress in the Retinal Endothelium. Int J Mol Sci. 2023 Jan 26;24(3). doi: 10.3390/ijms24032420. PMID: 36768740; PMCID: PMC9916835. 228. Sorenson CM, Song YS, Wang S, Darjatmoko SR, Saghiri MA, Ranji M, Sheibani N. Bim Expression of Modulates Branching Morphogenesis the Epithelium and Endothelium. Biomolecules. 2022 Sep 14;12(9):1295. doi: 10.3390/biom12091295. PMID: 36139134. 229. Spear JK, Grabowski M, Sekhavati Y, Costa CE, Goldstein DM, Petrullo LA, Peterson AL, Lee AB, Shattuck MR, Gómez-Olivencia A, Williams SA. Evolution of vertebral numbers in primates, with a focus on hominoids and the last common ancestor of hominins and panins. J Hum Evol. 2023 Jun;179:103359. doi: 10.1016/j. jhevol.2023.103359. Epub 2023 Apr 24. PMID: 37099927.

University of Wisconsin Department of Pediatrics | Annual Report 2023

PUBLICATIONS

230. Spiwak E, Bartosh SM, Smith J, Seifert ME, Amaral S, George RP. Assessment of Pediatric Kidney Transplant Experience and Exposure during Pediatric Nephrology Fellowship Training. Kidney360. 2023 Jun 8;. doi: 10.34067/KID.0000000000000177. [Epub ahead of print] PMID: 37287102. 231. Starr MC, Griffin R, Gist KM, Segar JL, Raina R, Guillet R, Nesargi S, Menon S, Anderson N, Askenazi DJ, Selewski DT; Neonatal Kidney Collaborative Research Committee (Jennifer R Charlton, Marissa DeFreitas, Mamta Fuloria, Mina Hanna, Matthew W Harer, Cara Slagle, Jonathan R Swanson, Keia Sanderson, Meredith P Schuh, Andrew M South, Heidi J Steflik, Robert Woroniecki, Michael Zappitelli). Association of Fluid Balance With Shortand Long-term Respiratory Outcomes in Extremely Premature Neonates: A Secondary Analysis of a Randomized Clinical Trial. JAMA Netw Open. 2022 Dec 1;5(12):e2248826. doi: 10.1001/jamanetworkopen.2022.48826. PMID: 36580332. 232. Sumski CA, Singh A, Rogers A, Treat R, Bergstrom C. Cardiac Physical Exam Skills and Auscultation Session for Pediatric Interns. MedEdPORTAL. 2022 Dec 20;18:11289. doi: 10.15766/mep_2374-8265.11289. PMCID: PMC9763479.

234. Tan W, Lin A, Keppler-Noreuil K. Cranioectodermal Dysplasia. 2013 Sep 12 [updated 2022 Dec 15]. In: Adam MP, Everman DB, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2022. PMID: 24027799. 235. Taneja R, Nahata MC, Scarim J, Pande PG, Scarim A, Hoddinott G, Fourie CL, Jew RK, Schaaf HS, Garcia-Prats AJ, Hesseling AC. Stable sugar and sugar-free suspensions of pretomanid. Int J Tuberc Lung Dis. 2022 Dec 1;26(12):1112-1117. doi: 10.5588/ijtld.22.0330. PMID: 36447311; PMCID: PMC9728945. 236. Taparli OE, Shahi PK, Cagatay NS, Aycan N, Ozaydin B, Yapici S, Liu X, Cikla U, Zafer D, Eickhoff JC, Ferrazzano P, Pattnaik BR, Cengiz P. Selectively compromised inner retina function following hypoxic-ischemic encephalopathy in mice: A noninvasive measure of severity of the injury. Neurochem Int. 2022 Dec 30:105471. doi: 10.1016/j. neuint.2022.105471. Epub ahead of print. PMID: 36592700.

233. Tahata S, Weckwerth J, Ligezka A, He M, Lee HE, Heimbach J, Ibrahim SH, Kozicz T, Furuya K, Morava E. Liver transplantation recovers hepatic N-glycosylation with persistent IgG glycosylation abnormalities: Three-year followup in a patient with phosphomannomutase-2congenital disorder of glycosylation. Mol Genet Metab. 2023 Apr;138(4):107559. doi: 10.1016/j. ymgme.2023.107559. Epub 2023 Mar 17. PMID: 36965289; PMCID: PMC10164344.

pediatrics.wisc.edu

PUBLICATIONS

237. Tenney AP, Di Gioia SA, Webb BD, Chan WM, de Boer E, Garnai SJ, Barry BJ, Ray T, Kosicki M, Robson CD, Zhang Z, Collins TE, Gelber A, Pratt BM, Fujiwara Y, Varshney A, Lek M, Warburton PE, Van Ryzin C, Lehky TJ, Zalewski C, King KA, Brewer CC, Thurm A, Snow J, Facio FM, Narisu N, Bonnycastle LL, Swift A, Chines PS, Bell JL, Mohan S, Whitman MC, Staffieri SE, Elder JE, Demer JL, Torres A, Rachid E, Al-Haddad C, Boustany RM, Mackey DA, Brady AF, Fenollar-Cortés M, Fradin M, Kleefstra T, Padberg GW, Raskin S, Sato MT, Orkin SH, Parker SCJ, Hadlock TA, Vissers LELM, van Bokhoven H, Jabs EW, Collins FS, Pennacchio LA, Manoli I, Engle EC. Noncoding variants alter GATA2 expression in rhombomere 4 motor neurons and cause dominant hereditary congenital facial paresis. Nat Genet. 2023 Jun 29. doi: 10.1038/s41588-023-01424-9. Epub ahead of print. PMID: 37386251. 238. Thakar MS, Logan BR, Puck JM, Dunn EA, Buckley RH, Cowan MJ, O’Reilly RJ, Kapoor N, Satter LF, Pai SY, Heimall J, Chandra S, Ebens CL, Chellapandian D, Williams O, Burroughs LM, Saldana BD, Rayes A, Madden LM, Chandrakasan S, Bednarski JJ 2nd, DeSantes KB, Cuvelier GDE, Teira P, Gillio AP, Eissa H, Knutsen AP, Goldman FD, Aquino VM, Shereck EB, Moore TB, Caywood EH, Lugt MTV, Rozmus J, Broglie L, Yu LC, Shah AJ, Andolina JR, Liu X, Parrott RE, Dara J, Prockop S, Martinez CA, Kapadia M, Jyonouchi SC, Sullivan KE, Bleesing JJ, Chaudhury S, Petrovic A, Keller MD, Quigg TC, Parikh S, Shenoy S, Seroogy C, Rubin T, Decaluwe H, Routes JM, Torgerson TR, Leiding JW, Pulsipher MA, Kohn DB, Griffith LM, Haddad E, Dvorak CC, Notarangelo LD. Measuring the effect of newborn screening on survival after haematopoietic cell transplantation for severe combined immunodeficiency: a 36-year longitudinal study from the Primary Immune Deficiency Treatment Consortium. Lancet. 2023 Jun 20:S0140-6736(23)00731-6. doi: 10.1016/S0140-6736(23)00731-6. Epub ahead of print. PMID: 37352885.

239. Tiedt K, Baker R, Rushton J, Ciccarelli M; Association of Pediatric Program Directors Faculty and Professional Development Learning Community. Fundamentals of Self-Directed Learning (SDL). Acad Pediatr. 2023 Jan 24:S1876-2859(23)00009-8. doi: 10.1016/j. acap.2023.01.009. Epub ahead of print. PMID: 36706866. 240. Tiedt K, Webber S, Babal JC, Nackers KAM, Allen A, Nacht CL, Coller RJ, Eickhoff J, Sklansky DJ, Kieren M, Shadman KA, Kelly MM. Gender difference in teaching evaluation scores of pediatric faculty. Acad Pediatr. 2022 Jul 29;. doi: 10.1016/j.acap.2022.07.017. [Epub ahead of print] PMID: 35914732. 241. Tobik K, Orland KM, Zhang X, Garcia K, Peterson AL. Parental Attitudes and Ideas Regarding Newborn Screening for Familial Hypercholesterolemia. Matern Child Health J. 2023 Mar 25. doi: 10.1007/s10995-023-036405. Epub ahead of print. PMID: 36964843. 242. Trangenstein PJ, Gora Combs K, Whitehill JM, Jenkins MC, Jernigan DH, Moreno MA. Typology of Adolescents Exposed to Nonmedical Cannabis Marketing and Associations with Consumption Patterns. Prev Sci. 2022 Oct;23(7):1276-1286. doi: 10.1007/s11121-02201378-0. Epub 2022 May 27. PMID: 35622192; PMCID: PMC10326727. 243. Tu WC, McManamen AM, Su X, Jeacopello I, Takezawa MG, Hieber DL, Hassan GW, Lee UN, Anana EV, Locknane MP, Stephenson MW, Shinkawa VAM, Wald ER, DeMuri GP, Adams K, Berthier E, Thongpang S, Theberge AB. At-home oral bacteria collection using a lollipop-based microfluidic device. bioRxiv [Preprint]. 2023 Jan 14:2023.01.14.524039. doi: 10.1101/2023.01.14.524039. PMID: 36711895; PMCID: PMC9882111.

University of Wisconsin Department of Pediatrics | Annual Report 2023

PUBLICATIONS

244. Van der Laan LE, Garcia-Prats AJ, Schaaf HS, Chirehwa M, Winckler JL, Mao J, Draper HR, Wiesner L, Norman J, McIlleron H, Donald PR, Hesseling AC, Denti P. Pharmacokinetics and Dose Optimization Strategies of ParaAminosalicylic Acid in Children with RifampicinResistant Tuberculosis. Antimicrob Agents Chemother. 2022 Jun 21;66(6):e0226421. doi: 10.1128/aac.02264-21. Epub 2022 May 4 PMID: 35506699 245. Voelz K, Salvatore A, Damodharan S, LeeMiller C. Need for pneumococcal revaccination after blinatumomab therapy: A case report. Pediatr Blood Cancer. 2023 Feb 1:e30237. doi: 10.1002/pbc.30237. Epub ahead of print. PMID: 36726210. 246. Vonasek BJ, Rabie H, Hesseling AC, GarciaPrats AJ. Tuberculosis in Children Living With HIV: Ongoing Progress and Challenges. J Pediatric Infect Dis Soc. 2022 Oct 31;11(Supplement_3):S72-S78. doi: 10.1093/ jpids/piac060. PMID: 36314545. 247. Wademan DT, Hoddinott G, Purchase SE, Seddon JA, Hesseling AC, Garcia-Prats AJ, Reis R, Reynolds LJ. Practical and psychosocial challenges faced by caregivers influence the acceptability of multidrug-resistant tuberculosis preventive therapy for young children. PLoS One. 2022 Jul 14;17(7):e0268560. doi: 10.1371/ journal.pone.0268560. eCollection 2022. PMID: 35834509.

249. Wald ER. Antimicrobial Stewardship and the American Academy of Pediatrics 2013 Acute Otitis Media Guideline: Interpretation? Misinterpretation? A Call to Action. J Pediatric Infect Dis Soc. 2022 Dec 3:piac122. doi: 10.1093/jpids/piac122. Epub ahead of print. PMID: 36461706. 250. Wancewicz B, Zhu Y, Fenske RJ, Weeks AM, Wenger K, Pabich S, Daniels M, Punt M, Nall R, Peter DC, Brasier A, Cox ED, Davis DB, Ge Y, Kimple ME. Metformin Monotherapy Alters the Human Plasma Lipidome Independent of Clinical Markers of Glycemic Control and Cardiovascular Disease Risk in a Type 2 Diabetes Clinical Cohort. J Pharmacol Exp Ther. 2023 Aug;386(2):169-180. doi: 10.1124/ jpet.122.001493. Epub 2023 Mar 14. PMID: 36918276; PMCID: PMC10353072. 251. Wang W, Lozar T, Golfinos AE, Lee D, Gronski E, Ward-Shaw E, Hayes M, Bruce JY, Kimple RJ, Hu R, Harari PM, Xu J, Keske A, Sondel PM, Fitzpatrick MB, Dinh HQ, Lambert PF. Stress Keratin 17 Expression in Head and Neck Cancer Contributes to Immune Evasion and Resistance to Immune-Checkpoint Blockade. Clin Cancer Res. 2022 Jul 1;28(13):2953-2968. doi: 10.1158/1078-0432.CCR-21-3039. PMID: 35621713; PMCID: PMC9250640.

248. Wademan DT, Palmer M, Purchase S, van der Zalm MM, Osman M, Garcia-Prats AJ, Seddon JA, Schaaf HS, Hesseling AC, Reis R, Reynolds LJ, Hoddinott G. Toward a conceptual framework of the acceptability of tuberculosis treatment in children using a theory generative approach. PLOS Glob Public Health. 2022 Dec 22;2(12):e0001267. doi: 10.1371/journal. pgph.0001267. PMID: 36962908; PMCID: PMC10021666.

pediatrics.wisc.edu

PUBLICATIONS

252. Washington C 3rd, Dapas M, Biddanda A, Magnaye KM, Aneas I, Helling BA, Szczesny B, Boorgula MP, Taub MA, Kenny E, Mathias RA, Barnes KC; CAAPA, Khurana Hershey GK, Kercsmar CM, Gereige JD, Makhija M, Gruchalla RS, Gill MA, Liu AH, Rastogi D, Busse W, Gergen PJ, Visness CM, Gold DR, Hartert T, Johnson CC, Lemanske RF Jr, Martinez FD, Miller RL, Ownby D, Seroogy CM, Wright AL, Zoratti EM, Bacharier LB, Kattan M, O’Connor GT, Wood RA, Nobrega MA, Altman MC, Jackson DJ, Gern JE, McKennan CG, Ober C. Africanspecific alleles modify risk for asthma at the 17q12-q21 locus in African Americans. Genome Med. 2022 Sep 29;14(1):112. doi: 10.1186/ s13073-022-01114-x. PMID: 36175932; PMCID: PMC9520885. 253. Watkinson MD, Ehlenbach M, Chung PJ, Kelly M, Werner N, Jolliff A, Katz B, Marleau H, Nacht CL, Warner G, Coller RJ. Interventions in the Home and Community for Medically Complex Children: A Systematic Review. Pediatrics. 2023 May 1;151(5). doi: 10.1542/peds.2022-058352. PMID: 37051803. 254. Webb BD, Nowinski SM, Solmonson A, Ganesh J, Rodenburg RJ, Leandro J, Evans A, Vu HS, Naidich TP, Gelb BD, DeBerardinis RJ, Rutter J, Houten SM. Recessive pathogenic variants in MCAT cause combined oxidative phosphorylation deficiency. Elife. 2023 Mar 7;12:e68047. doi: 10.7554/eLife.68047. PMID: 36881526; PMCID: PMC9991045. 255. Webber S, Kloster H, Shadman KA, Kelly M, Sklansky D, Coller RJ. Domains of professional fulfillment for pediatric hospital medicine: A concept mapping study. J Hosp Med. 2023 May 9;. doi: 10.1002/jhm.13119. [Epub ahead of print] PMID: 37158170.

256. Webber SA, Byrne BJ, Starmer AJ, Somberg CA, Frintner MP. Examining Early Career Pediatrician Characteristics, Sacrifices, and Satisfaction. Acad Pediatr. 2023 Jan 19:S1876-2859(23)00006-2. doi: 10.1016/j. acap.2023.01.005. Epub ahead of print. PMID: 36682450. 257. Weinfurter JT, D’Souza SS, Matschke LM, Bennett S, Kelnhofer-Millevolte LE, Suknuntha K, Kumar A, Coonen J, Capitini CM, Hematti P, Golos TG, Slukvin II, Reynolds MR. Allogeneic MHC-matched T-cell receptor α/β-depleted bone marrow transplants in SHIV-infected, ART-suppressed Mauritian cynomolgus macaques. Sci Rep. 2022 Jul 19;12(1):12345. doi: 10.1038/s41598-022-16306-z. PMID: 35853970; PMCID: PMC9296477. 258. Werner NE, Fleischman A, Warner G, Barton HJ, Kelly MM, Ehlenbach ML, Wagner T, Finesilver S, Katz BJ, Howell KD, Nacht CL, Scheer N, Coller RJ. Feasibility Testing of Tubes@HOME: A Mobile Application to Support Family-Delivered Enteral Care. Hosp Pediatr. 2022 Jul 1;12(7):663-673. doi: 10.1542/ hpeds.2022-006532. PMID: 35670137; PMCID: PMC10334453. 259. Whitman A, Damodharan S, Bhatia A, Puccetti D, Iskandar B. Hemangioblastoma and mosaic von Hippel Lindau disease: rare presentation and review of the literature. Childs Nerv Syst. 2023 May;39(5):1361-1363. doi: 10.1007/s00381-023-05859-7. Epub 2023 Jan 28. PMID: 36708374. 260. Williams KB, Lasarev MR, Baker M, Seroogy CM. Cross-sectional survey on genetic testing utilization and perceptions in Wisconsin Amish and Mennonite communities. J Community Genet. 2023 Feb;14(1):41-49. doi: 10.1007/ s12687-022-00621-z. Epub 2022 Nov 17. PMID: 36385695; PMCID: PMC9947211.

University of Wisconsin Department of Pediatrics | Annual Report 2023

PUBLICATIONS

261. Williams L, Baker-Smith CM, Bolick J, Carter J, Kirkpatrick C, Ley SL, Peterson AL, Shah AS, Sikand G, Ware AL, Wilson DP. Nutrition interventions for youth with dyslipidemia: a National Lipid Association clinical perspective. J Clin Lipidol. 2022 Jul 30:S19332874(22)00218-5. doi: 10.1016/j.jacl.2022.07.011. Epub ahead of print. PMID: 36109324. 262. Wong J, Densmore J, Hilbrands J, Elkadri A, Cabrera J, Noe J, Eickhoff J, Goday PS. Perioperative nutrition in the setting of pediatric inflammatory bowel disease. Nutr Clin Pract. 2023 Jun 11. doi: 10.1002/ncp.11021. Epub ahead of print. PMID: 37302062 263. Woodring T, Deepe GS, Levitz SM, Wuethrich M, Klein BS. They shall not grow mold: Soldiers of innate and adaptive immunity to fungi. Semin Immunol. 2022 Nov 29;65:101673. doi: 10.1016/j. smim.2022.101673. Epub ahead of print. PMID: 36459927. 264. Zafer D, Adams T, Olson E, Stenman L, Taparli O, Eickhoff J, Cengiz P, Mezu-Ndubuisi OJ. Retinal vascular recovery revealed by retinal imaging following neonatal hypoxia ischemia in mice: Is there a role for tyrosine kinase receptor modulation? Brain Res. 2022 Sep 15;1796:148093. doi: 10.1016/j. brainres.2022.148093. Epub ahead of print. PMID: 36116486. 265. Zaitoun IS, Song YS, Zaitoun HB, Sorenson CM, Sheibani N. Assessment of choroidal vasculature and innate immune cells in the eyes from albino and pigmented mice. Cells. 2022 Oct 21;11(20):3329. doi: 10.3390/cells11203329. PMID: 36291198; PMCID: PMC9600292. 266. Zaman Z, Henry SJ, Birkeland LE, Petty EM. Nine Successful Pregnancy Outcomes in a Woman With Vascular Ehlers-Danlos Syndrome: A Case Report and Literature Review. WMJ. 2022 Dec;121(4):e71-e74. PMID: 36637850.

267. Zavaletta V, Allen BJ, Parikh AK. Re-defining gender diversity through anequitable and inclusive lens. Pediatr Radiol. 2022 Aug;52(9):1743-1748. doi: 10.1007/s00247-02205332-8. Epub 2022 Mar 22. Review. PMID: 35316338. 268. Zevin EL, Peterson AL, Dodge A, Zhang X, Carrel AL. Low HDL-C is a non-fasting marker of insulin resistance in children. J Pediatr Endocrinol Metab. 2022 Jul 26;35(7):890-894. doi: 10.1515/jpem-2021-0751. Print 2022 Jul 26. PMID: 35649511; PMCID: PMC9249377. 269. Zhang J, Webster S, Duffin B, Bernstein MN, Steill J, Swanson S, Forsberg MH, Bolin J, Brown ME, Majumder A, Capitini CM, Stewart R, Thomson JA, Slukvin II. Generation of antiGD2 CAR macrophages from human pluripotent stem cells for cancer immunotherapies. Stem Cell Reports. 2023 Feb 14;18(2):585-596. doi: 10.1016/j.stemcr.2022.12.012. Epub 2023 Jan 12. PMID: 36638788; PMCID: PMC9968983. 270. Zhang Y, Sriramaneni RN, Clark PA, Jagodinsky JC, Ye M, Jin W, Wang Y, Bates A, Kerr CP, Le T, Allawi R, Wang X, Xie R, Havighurst TC, Chakravarty I, Rakhmilevich AL, O’Leary KA, Schuler LA, Sondel PM, Kim K, Gong S, Morris ZS. Multifunctional nanoparticle potentiates the in situ vaccination effect of radiation therapy and enhances response to immune checkpoint blockade. Nat Commun. 2022 Aug 23;13(1):4948. doi: 10.1038/s41467022-32645-x. PMID: 35999216; PMCID: PMC9399096. 271. Zou Y, de Jager V, Hesseling AC, Diacon AH, Wiesner L, Mostert J, Svensson EM, GarciaPrats A. Relative bioavailability of delamanid 50 mg tablets dispersed in water in healthy adult volunteers. Br J Clin Pharmacol. 2023 Jan 24. doi: 10.1111/bcp.15672. Epub ahead of print. PMID: 36692865.

pediatrics.wisc.edu

PUBLICATIONS

272. Zwemer E, Serwint JR, Sieplinga K, Wilson PM, Webber S, Lien ER, Babal JC, Donnelly KM, Nichols MH, Batra M, Schwartz A, Reese JW. Implementation and maturity of clinical learning environment components across pediatric residency programs. Acad Pediatr. 2023 Apr 22;. doi: 10.1016/j.acap.2023.04.008. [Epub ahead of print] PMID: 37094643.

University of Wisconsin Department of Pediatrics | Annual Report 2023

PUBLICATIONS

pediatrics.wisc.edu