UK Food-Grown® Training

A bit of background Are supplements necessary Understanding human nutrient metabolism Avoiding confusion: Different forms of supplements The FOOD-GROWN process ®

What are the advantages of FOOD-GROWN Scientifically grounded

®

A bit of background

The future of supplements Co-Founded by Charlie & Henrietta Norton 2013 UK manufactured Unique formulations of FOOD-GROWN nutrients and botanicals for life and age stages ÂŽ

Based on expertise in Nutritional Medicine

Henrietta Norton BSc, DIP NT Foresight Preconception Practitioner AFMCP Institute of Functional Medicine MSc in Nutritional Medicine 10 years experience product formulation Nutritional clinics in London Health writer and author of: Take Control of Your Endometriosis Your Pregnancy Nutrition Guide: What to Eat When You’re Pregnant

Why do we need supplements?

Lifestyle trends Our farming techniques Our soil

100 80

85% 76%

60

76%

74%

72% 55%

40 20 0

Why is detoxification important?

N. America

S. America

Asia

Africa

Europe

Australia

“Selenium is desperately low in virtually all UK soils and, as admitted by MAFF, its intake is half what it should be in the human population due to removal by cropping and to leaching by the sulphate in acid rain and ammonium sulphate fertilizers” Select Committee on Environment, Food & Rural Affairs 2004

So, do we need supplements?

Yes we do, but in a form the body recognises As with food, how much we absorb and metabolise is perhaps more crucial

Understanding nutrient metabolism

“Human physiology will always be able to distinguish between Vitamin C in synthetic form and that from an orange”

Dr Albert Szent Gyorgyi, MD, PhD, Nobel laureate

Bioavailability is more than ‘absorption’ Why is detoxification important?

Carrier Food Factors (CFF’s) Absorption – envelope Transport – name Metabolism – address Retention – special Delivery

Beyond bioavailability – CCF’s Dr Gonter Blobel, 1999 Nobel Prize winner “Each protein carries in its structure the information needed to specify its proper location in the cell. These are universal, operating similarly in single cell plant and animal cells. The knowledge of protein chaperons (carriers) will increase our understanding of processes leading to disease and can be used to develop new therapeutic strategies”

Why is detoxification important?

Dr Thomas O’Halloran, 1997 Peer-reviewed study on the process of protein chaperones for intracellular nutrient delivery

Nutrients in nature are never found in isolation Why is detoxification important?

“Separating (fractionating) the group or the compounds into single, incomplete vitamin portions convert it from a physiological, biochemical, active micronutrient into a disabled, debilitating chemical of little or no value to living foods.”

Judith De Cava, The Real Truth About Vitamins & Antioxidants

Isolate synthetics need “re-combining” before they can function systemically Steals the missing pieces from body reserves Or excreted through the kidneys1

1. Richard P Murray “what is a vitamin?” Lecture Manual, Biomedical Health Foundation 1993 p.1

“When dosing with synthetic isolate vitamins, there is an apparent physiological response, but after a period of time the body tissue reserves of the complexing synergists are depleted and the apparent improvements lost2” 2. Principles of Biochemistry, Second Ed. Abraham White. PhD et al. New York:McGraw-Hill Book Company. Inc., 1959) p.1044

Avoiding confusion: Dierent forms of supplements

Synthetic isolate food supplements Isolates, Chelates Synthetic isolate nutrients combined with plant/whole-food extracts Fermented

The FOOD-GROWN process ®

Replicating the plant kingdom – Endre Szalay Pharmacognosist and the discoverer of the FOOD-GROWN process ®

“intermediary form of ascorbic acid – one that resembled food without the bulk of food – was more effective at reducing scurvy than the cystalline form” ‘Reverse engineer’ the work of Szent Gyorgyi

Our FOOD-GROWN® process summary We don’t make our supplements, we grow them. Essential nutrients are carefully grown in food – transforming them into food too and increasing their potency. This is the secret power of FOOD-GROWN supplements. ®

1. We begin with fresh, whole food

2. We use every part of the food

3. And reduce it to a fine food paste

4. The food paste is put in special tanks and enriched with super nutrients

5. Each super nutrient has a very high nutritional value

6. And has been cleverly attached to a glycoprotein

=

7. This means the food paste recognises and allows the super nutrients into its matrix

8. The super nutrients bond, grow and transform to become part of the food paste

9. The result is a super nutritious food paste that is bioavailable (your body will now accept the super nutrients and use them)

10. The super nutritious food paste is washed and spray-dried into powder

11. The powder is then encapsulated and packaged in protective jars

FOOD-GROWN benefits ®

Food-Grown Vitamin C ÂŽ

Carbohydrates Proteins Lipids Enzymes Glycoproteins Lipoproteins Bioflavonoids Phospholipids Fatty acids Amino acids Ascorbic Acid & reduced forms = Letter, envelope, full name, house number, street, post code, Special delivery

vs

Chemical isolate

Only the chemical Isolate Ascorbic Acid Devoid of all metabolically bound synergists = Letter, envelope, name, city

Drug effect vs nutritional healing “A vitamin is a substance that makes you ill if you do not eat it in a natural food matrix form”.

Dr Albert Szent Gyorgy

Scientifically grounded

Scientific studies Over 50 independent studies have found that Food-GrownÂŽ nutrients are more eďŹƒcient than synthetic Isolate supplements or Amino acid chelates.

They are delivered in a form recognized by the body as food They work with the body’s natural metabolism They provide increased cellular receptor recognition

Food-Grown Iron ®

The relative bioavailability of iron amino acid chelate was 57% and 72% in the blood and liver respectively, whereas Food-Grown® Iron’s bioavailability was 101% and 121% in the blood and liver respectively.

Relative increase %

150

150

135

135

120

120

105

105

90

90 Relative increase %

75 60

75 60

45

45

30

30

15

15

0

0 Ferrous Sulfate

Amino Acid Chelate Absorbed into blood

Food-Grown Iron

®

Ferrous Sulfate

Amino Acid Chelate

Food-Grown ® Iron

Retained in liver

Name of study: Nutrient availability: Chemical and Biological Aspects Conducted by: J.A. Vinson et al.

Publication: Royal Society of Chemistry, Scranton, USA. 1989

Food-Grown Vitamin C ®

Food-Grown® Vitamin C was found to be 35% better absorbed than the isolate ascorbic acid. Food-Grown® Vitamin C was also found to be better retained within the body than ascorbic acid, as demonstrated by lower excretion in the urine.

Vitamin C Animal Long Term Absorption Study

Vitamin C Human Absorption Study

150

200

135

180

120

160

105

140

90

120

Relative 75 increase 60 %

Relative 100 increase 80 %

45

60

30

40

15

20 0

0 USP

Food-Grown

Absorbed into blood

®

USP

Food-Grown ®

Absorbed into red blood cells

Name of study: Comparative bioavailability to humans of ascorbic acid alone or in a citrus extract Conducted by: J.A. Vinson, P. Bose Publication: American Journal of Clinical Nutrition 1998; Sep:48 (3):601-4

Food-Grown Calcium ®

Food-Grown® Calcium was found to be better absorbed than either calcium carbonate or calcium gluconate.

Calcium Human Study

900

NET 24-hour urine excretion (post dose - pre dos e) Relative % Excretion

810 720 630 540 Relative increase %

450 360 270 180 90 0 Calcium Carbonate

Calcium Gluconate

Food-Grown ® Calcium

Retained in liver

Name of study: Nutrient availability: Chemical and Biological Aspects Conducted by: J.A. Vinson et al.

Publication: Royal Society of Chemistry, Scranton, USA. 1989

Food-Grown Minerals ®

Yeast is the most bioavailable form of the element and is therefore the best form of trace element supplementation for animal and man.

Animal Study – Bioavailability of Zinc

200

200

180 160 140 120 Relative increase %

Animal Study – Bioavailability of Zinc

700

400

180

630

360

160

560

320

140

490

280

120 Relative increase %

100 80

420 Relative increase %

100 80

240 Relative increase %

350 280

200 160

60

60

210

120

40

40

140

80

20

20

70

40

0

0

0 Zinc Sulfate

Amino Acid Chelate Absorbed into blood

Food-Grown ® Zinc

Zinc Sulfate

Amino Acid Chelate Retained in liver

Food-Grown ® Zinc

0 Zinc Gluconate

Zinc Orotate Absorbed into blood

Food-Grown ® Zinc

Zinc Gluconate

Zinc Orotate Retained in liver

Name of study: Comparison of the bioavailability of trace elements in inorganic salts, amino acid chelates and yeast Conducted by: D. Southgate, I.T. Johnson and G.R. Fenwick Publication: Proceedings on mineral elements Part 2, 1981: 615-621

Food-Grown ® Zinc

Results from scientific studies Are effective at ‘natural doses’ & have ‘selective absorption’ Higher absorption and cellular retention Does not cause concern about interactions between nutrients Proven success in preventative and treatment applications in disease

FOOD-GROWN® works where

synthetics might not:

Serum protein glycation was reduced by an average of 46.8% after 4 weeks’ supplementation with FOOD-GROWN Vitamin C. Protein glycation is a significant mechanism behind the development of diabetic complications. ®

Nutritional Biochemistry 7, 659-663. 1996. ®

The FOOD-GROWN vitamin C in a citrus extract containing bioflavonoids was 41% more effective than ascorbate alone in decreasing galacticol.

Nutrition Research, 12. 915-922. 1992.

In a double-blind, placebo-controlled study with 26 normal and hypercholesterolemic subjects, the citrus extract and vitamin C, but not vitamin C or vitamin E alone, significantly lowered triglycerides Journal of Medicinal Foods, 2001, Volume 4, Number 4, Pages 187-192.

Drug effect vs nutritional healing “A vitamin is a substance that makes you ill if you do not eat it in a natural food matrix form”.

Dr Albert Szent Gyorgy

US Supreme Court ruling 1993 Studies indicate that Food-Grown® materials are metabolically different from vitamins mixed with foods Food-Grown® materials are better than isolated USP materials Food-Grown® materials may be better absorbed, retained and utilised than USP nutrients Food-Grown® materials are manufactured under a proprietary process

“Wild Nutrition’s formulations are created with awareness and respect for the biochemical environment and homeostatic need in the body. I haven’t seen formulations as impressive as these for many years.”

Dr Eric Llewellyn, researcher in Nutrition & Holistic Health (Founder of Cytoplan)

“There is no doubt in my mind that Food-Grown technology solves our nutritional problems.

It provides doctors and other therapists with a harmless, yet potent, means of healing. At last, health seems attainable by us all.”

Why is detoxification important?

Dr Peter Mansfield

“…In 15 years of using this material, nothing else coming close” Dr Kim Jobst

Why is detoxification important?

“Discovery consists of looking at the same thing as everyone else and thinking something different” Dr Albert Szent Gyorgyi, MD, PhD, Nobel laureate

Published studies Title: Authors: Section: Article:

Blood Coagulation & Fibrinolysis, 2004 Loots, D., Oosthuizen, W., Pieters, M., Spies, C., and Vorster, H.H. Volume 15(8), Pages 677-685 Food State vitamin C complex may beneficially affect haemostasis and fibrin network structure in hyperlipidaemic patients

Title: Authors: Section: Article:

Journal of Medicinal Foods, 2001 Vinson, J.A. and Jang, J. Volume 4, Number 4, Pages 187-192. Copyright © Mary Ann Liebert Inc. In Vitro and in Vivo lipoprotein antioxident effect of a citrus extract and ascorbic acid on normal and hypercholesterolemic human subjects (Abstract)

Title: Authors: Section: Article:

Journal of Agricultural and Food Chemistry, 1998 Vinson, J.A., Hu, S., Jung, S., and Stanski, A.M. Volume 46, Number 4, Pages 1453–1459, A citrus extract plus ascorbic acid decreases lipids, lipid peroxides, lipoprotein oxidative susceptibility and atherosclerosis in hypercholesterolemic hamsters (Abstract)

Title: Authors: Section: Article:

Nutritional Biochemistry, 1996 Vinson, J.A. and Howard, T.B. III Volume 7, Pages 659-663. Copyright © Elsevier Science, Inc. Inhibition of protein glycation and advanced glycation end products by ascorbic acid and other vitamins and nutrients (Abstract)

Title: Authors: Section: Article:

Irish Journal of Medical Science, 1993 Cahill, R.J., O'Sullivan, K., Beattie, S., Hamilton, H., and O'Morain, C. Volume 162(7), Page 285.

Celladenomatous polyps. kinetic effects on selenium and vitamin C in subjects

Title: Authors: Section: Article:

European Journal of Cancer Prevention, 1993.

Cahill, R.J., O'Sullivan, K., Beattie, S., Hamilton, H., and O'Morain, C. Volume 2, Supp 1, Page 28 Effect of selenium and vitamin C on colonic crypt cell proliferation.

1 year follow up study

Title: Authors: Section: Article:

Gut, 1993, Cahill, R.J., O'Sullivan, Mathias, P.M., Beattie, S., Hamilton, H., and O'Morain, C. Volume 34, Pages 963-967 Effects of vitamin antioxidant supplementation on cell kinetics of patients with adenomatous polyps

Title: Authors: Section: Article:

Med. Sci. Res., 1992 Vinson, J.A. and Hsu, C. Volume 20, Pages 145–146, Effect of vitamins A, E and a citrus extract in vitro and in vivo lipid peroxidation

Title: Authors: Section: Article:

Nutrition Research, 1992 Vinson, J.A., Courey, B.S., and Maro, N.P. Volume 12, Pages 915-92 Copyright © American Diabetes Association Comparison of two forms of vitamin C on Galactose cataracts

Title: Authors: Section: Article:

Reduction of Sorbitol by Vitamin C, 1989 Vinson, J.A., Staretz, M.E., Bose, P., Kassm, H.M., and Basalyga, B.S. Pages 1-8 Copyright © American Diabetes Association In Vitro and In Vivo reduction of Erythrocyte Sorbitol by Ascorbic Acid

Title: Authors: Section:

American Journal of Clinical Nutrition, 1988 Vinson, J.A. and Bose, P. Volume 48, No. 3, Pages 601-604 Copyright © 1988 by The American Society for Clinical Nutrition, Inc. Comparative bioavailability to humans of ascorbic acid alone or in a citrus extract (Abstract)

Article:

Title: Authors: Section: Article:

Nutrition Reports International, 1987 Vinson, J.A., Mazur, T. and Bose, P. Volume 36, No. 3, Comparison of different forms of calcium on blood pressure of normotensive young males

Title: Authors: Section: Article:

Nutrition Reports International, 1985 Vinson, J.A. and Hsiao, K. Volume 32, No. 1 Comparative effect of various forms of chromium on serum glucose.

An assay for biologically active chromium (Abstract)

Title: Authors: Section: Article:

Nutrition Reports International, 1984 Vinson, J.A. and Bose, P. Volume 30, No. 4 The effect of high chromium yeast in the blood glucose control and blood lipids of normal and diabetic human subjects.