TurmaForte Full Spectrum Turmeric

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PRODUCT SUMMARY & TECHNICAL GUIDE FOR PROFESSIONAL USE ONLY

TURMAFORTE

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FULL SPECTRUM TURMERIC WNTT-GL12

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SKU: WNTT-GL12

TURMAFORTE FULL SPECTRUM TURMERIC

Introduction & Contents This is without doubt the most advanced and exciting Turmeric product on the market. Using organically sourced Turmeric root and a 3-stage advanced technology this unique product offers a full spectrum of active fractions at therapeutic levels, clinically-tested to benefit those experiencing inflammation-related conditions.

The provenance of any herb, botanical or nutrient that is used in our formulas is deeply important to me.

Turmaforte® Turmeric reflects the intelligence of Mother nature combined with the latest technolgical scientific research and is both organic and sustainable. I am therefore delighted that this incredible product is now available within our range and is already supporting my clients and my family’s wellbeing.

Henrietta Norton BSc Dip NT Founder and Formulator of Wild Nutrition

Contents Introduction

2

Product Summary

3

Technical & Product Training

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Comprehensive Studies

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Product Summary Key Benefits ++ Organic and sustainably sourced ++ Clinically-proven to reduce joint pain by 86.2% within 21 days of use and reduced cartilage degeneration, joint tenderness and inflammation ++ Antioxidant and seasonal support ++ Promotes healthy liver detoxification ++ Supports female inflammatory conditions such as endometriosis and female specific metabolic syndrome such as PCOS ++ Supports fertility for women and men Size: 60 capsules (1 month supply). Recommended for: 3+ Recommended dose: 2-3 capsules per day with or without food. For acute symptoms the dose may be increased to 3-4 capsules per day.

Key Features ++ Advanced technology providing a full spectrum of active fractions: This proprietary extraction provides an orchestra of beneficial fractions enabling TurmaForte® Turmeric to have higher biological activity and therapeutic value, reflected in excellent outcomes in clinical studies.

No artificial colours

No artificial flavourings

No artificial preservatives

Excipient-free

No ar colo

Wheat-free

Soya-free

Gluten- free

Corn-free

Whea

++ More than just curcuminoids and curcumin: TurmaForte Turmeric contains curcumin, curcuminoids as well as tumerosaccarides and tumerones. ®

++ Contains Turmeric essential oils: Biologically important volatile oils are often overlooked in the singular pursuit of the popular curcuminoid fraction.

Our formula includes these essential oils and research shows they demonstrate anti-inflammatory activity.

Vegan

Ve

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Our TurmaForte® Full Spectrum Turmeric is an advanced, clinically-proven, organic Turmeric, harnessing a proprietary extraction process to provide not just one but three therapeutically active constituents of this beneficial plant, including curcuminoids, turmerosaccharides and turmerone volatile oils. Standard Turmeric preparations focus on curcumin and curcuminoids alone, ignoring the potent and therapeutic value of these other fractions of this powerful ayurvedic plant.

Our advanced TurmaForte® Turmeric reflects the intelligence and natural balance of the whole plant and optimises its potent therapeutic benefits. Clinical research has shown TurmaForte® Turmeric reduces the experience of joint pain of users by 86.2% within just 21 days.*

TURMAFORTE FULL SPECTRUM TURMERIC

Product Information Two capsules provide:

Claim

% EU NRV*

1000mg

N/A

Organic Turmeric extract (curcuma longa) 20:1 Providing: Curcuminoids (curcumin, desmethoxycurcumin, bisdesmethoxycurcumin) min. 12.5% Turmerosaccharides min. 10%

*Madhu K, Chanda K, Saji MJ (2013) Safety and efficacy of Curcuma longa extract in the treatment of painful knee osteoarthritis: a randomized placebo-controlled trial Inflammopharmacology. Apr;21(2):129-36.

Ingredients Organic Turmeric extract (curcuma longa) 20:1, vegetable cellulose (capsule shell), curcuma longa rhizome essential oil.

Complementary Products BESPOKE MAN

FOOD-GROWN

®

Daily Multi Nutrient 45+

Free from BESPOKE WOMAN

Excipients, wheat, yeast, soya, artificial colours, added sugars, flavourings & preservatives.

Cautionary advice

FOOD-GROWN

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Daily Multi Nutrient 45+

GENERAL LIVING

FOOD-GROWN

®

If you are pregnant, breast feeding, taking medication, or under medical supervision, please consult your healthcare professional before taking any food supplement.

Bone Complex

Food supplements are not a substitute for a balanced diet and healthy lifestyle. Store in a cool dry place away from direct sunlight. Keep out of sight and reach of children.

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TURMAFORTE FULL SPECTRUM TURMERIC

Technical & Product Training TurmaForte® Turmeric is a unique, whole concentrated form of organic Turmeric (Curcuma longa) rhizome, using an advanced technological process to focus on three key and therapeutically important elements from the original Turmeric plant, including curcuminoids, turmerosaccarides and turmerone oils.

Background Turmeric rhizome has been used as a culinary spice in Asian and Indian cuisine for centuries, primarily for its flavouring and natural colourant properties. The traditional preparation involves boiling the fresh or dried rhizome to be used within curries and other savoury dishes.

As well as its culinary uses, Turmeric has had a rich history of medicinal use too, dating back to over 4,000 years within Ayurvedic medicine. In recent history, a growing body of scientific evidence has demonstrated Turmeric to be a natural remedy for a number of applications including inflammatory, digestive and hepatic disorders.

Sustainability Turmeric is widely cultivated in Southern India and is an important economic crop for the region.

Why TurmaForte Turmeric? ®

Standard production methods for Turmeric supplements focus on one fraction of the herb, namely curcumin and the curcuminoids. However, the power of this natural remedy is not in curcumin or the curcuminoids alone but rather in the orchestra of fractions found within the whole herb.

The proprietary process and advanced technology we use in TurmaForte® Turmeric allows us to concentrate and capture all critical elements available from the Turmeric rhizome, including curcuminoids, tumerosaccharides and tumerones, in the natural ratio as found within the whole herb.

How Is This Achieved?

Solvent fraction - Curcuminoids Many commercially available preparations of Turmeric focus on curcuminoids (curcumin, desmethoxycurcumin and bisdesmethoxycurcumin) comprising 95% of the total composition of the product. However, this reductionist method does not reflect the natural components of the herb and results in the removal of other valuable components such as turmerosaccharides and turmerones.

Our unique TurmaForte® Turmeric production process addresses this through the inclusion of these important curcuminoids along with two equally important chemical groups also present in the raw herb.

Water-soluble fraction – Concentrated Turmerosaccharides. High potassium.

Low sodium.

Using only water during the extraction process to capture and concentrate this important fraction of Turmeric, we are able to preserve both the polar and non-polar chemistry from the foundation plant material in the final TurmaForte® Turmeric extract.

Water extraction is consistent with the traditional method of preparation, which involves boiling the dried rhizome in water and consuming the broth.

Tumerosaccharides within our Turmaforte® Turmeric have been clinically tested for their role in relieving joint pain and restoring joint mobility. The published human study demonstrates that when tumerosaccharides are found in synergy with other fractions of turmeric, it provided statistically significant relief from joint pain within 21 days.

Efficacy was achieved with a twice-daily dose of 500mg of this fraction alone (1). Early research suggests this effect is being driven predominantly by the Ukonans (monosaccharides comprised of L-arabinose, D-xylose, D-galactose, D-glucose, L-rhamnose and D- galacturonic acid) within the tumerosaccharide fractions. The term Ukonan stems from the word ‘Ukon’, which is the Japanese name for Turmeric.

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This water-soluble component of the Turmeric rhizome is also high in potassium and low in sodium (approx.

10% and <0.25% respectively in TurmaForte® Turmeric).

This balance of Potassium: Sodium can help to restore dietary imbalances that are often seen in our Western populations (2), the effect of which can be hypertension and cardiovascular disease.

Hypertension is a recognised risk factor of osteoarthritis, influenced by factors such as excess weight or obesity, stress and the use of medications, such as NSAID’s that have increased risk of hypertension. (3).

In addition, curcumin (the dominant curcuminoid in the solvent fraction of TurmaForte® Turmeric) has been shown to have an effect on sodium/potassium pumps, influencing the balance of cellular potassium retention and sodium excretion. This has the potential to further validate the symbiotic value of the various fractions in TurmaForte® Turmeric (4).

Therefore, the water-soluble fraction of TurmaForte® Turmeric acts as an effective agent in relieving joint-pain without the cardiovascular side effects associated with commonly used joint pain-relief medications.

Oil fraction - Turmeric essential oils The final components of TurmaForte® Turmeric are the volatile oils which occur naturally in the Turmeric rhizome.

These biologically important volatile oils predominantly consist of turmerones (approximately 40% in the concentrated oil), the major constituent of which is ar-turmerone.

TURMAFORTE FULL SPECTRUM TURMERIC

Certifications ++ Non-GMO verified ++ Certified halal, GMP, ISO ++ Certified organic. However, Wild Nutrition cannot currently claim this product as organic on our labels due to our UK production facilities not being certified as organic.

Use & Dosage Size: 60 capsules (1 months supply).

Recommended for: 3+ Recommended dose: 2-3 capsules per day with or without food. 2 capsules provide 1,000mg. At this daily dose it provides the equivalent to 13g of whole turmeric root. For acute symptoms the dose may be increased to 3-4 capsules per day.

Suitable for vegans and vegetarians.

Overall it is a very safe plant to use but always check regarding medications prior to use, with specific caution given to anticoagulant medication. You may check any medication queries with our technical team. Turmaforte® Turmeric may also be used in pre-conception and in breastfeeding at the normal dose (2-3 capsules per day) or the acute dose. It may also be used in pregnancy at a dose of 1 capsule per day. Higher doses may be given if supervised by a qualified practitioner.

The Turmeric essential oils have themselves demonstrated anti-inflammatory activity (5) and are often regularly overlooked. By using steam distillation and concentration of the oil prior to the solvent and water extraction stages already described, TurmaForte® Turmeric reflects the complete Turmeric plant just as mother nature intended in a powerful, concentrated form.

Turmaforte® Turmeric contains high levels of turmerones and therefore negates the need to include phosphalipids or black pepper to support absorbency. This is because research has shown that turmerones are lipophilic and therefore aid in the transportation of other turmeric components such as curcumin and curcuminoids.* * www.ncbi.nlm.nih.gov/pmc/articles/PMC3282471/

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Full Benefits

Female Health Support

++ Tumerosaccharides within our Turmaforte® Turmeric have been clinically tested for their role in relieving joint pain and restoring joint mobility. The published human study demonstrates that when tumerosaccharides are found in synergy with other fractions of Turmeric, they provide statistically significant relief from joint pain within 21 days for 86.2% of users.

Turmeric supports by:

++ Clinically proven to reduce cartilage degeneration, joint tenderness, and joint inflammation.

++ Providing anti-inflammatory support and immune modulation. This is essential in female specific conditions that involve the immune system such as endometriosis (cytokine management) and in PCOS (metabolic syndrome). ++ Providing support during peri-menopause and menopause as some symptoms can be inflammation based or driven.

++ Support rheumatoid and osteoarthritis ++ Seasonal support for colds and flu. ++ Supports potassium and sodium balance for healthy cardiovascular health. ++ Optimises nutrient absorption by supporting blood flow, gastrointestinal healing and promoting digestive ‘fire’ for those with sluggish digestion. ++ All-round anti-inflammatory, antioxidant and immune modulator. Ideal for use in autoimmunity. ++ Supports the body when faced with pathogenic attack such as from bacterial or viral infection. ++ Turmeric is a traditional liver supporting herb.

Promoting healthy detoxification pathways and increasing bile, to move toxicants through the liver and the gut and safely out of the body. ++ Brain health, healthy-ageing and for mood health (especially in the link between the gut and the brain).

++ Upregulating phase 2 liver detoxification pathway.

This is essential when female hormone balance is reliant on ‘used’ hormones being excreted effectively but also safely from the body. ++ Providing immune modulation in thyroid autoimmune conditions such as Hashimoto’s thyroiditis that are statistically more common in women. ++ Working as an antioxidant in fertility cases where healthy immunity and egg preservation is required.

Turmeric works to support blood flow and this is beneficial for the blood supply to the womb. As an antioxidant rich plant, Turmeric will also be beneficial to sperm health.

Summary Turmaforte® Turmeric can be used alongside other Wild Nutrition products that contain Turmeric. Turmaforte® Turmeric is a concentrated therapeutic form. Whereas the Turmeric we use within other products is a high quality whole herb root powder. This whole herb is more like a food with excellent beneficial qualities but not with the ‘intensified’ therapeutic strength of Turmaforte® Turmeric.

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TURMAFORTE FULL SPECTRUM TURMERIC

Comprehensive Studies Clinical studies have shown the benefits of TurmaForte® Turmeric for the reduction of cartilage degeneration, 86.2% reduction of joint tenderness, increased mobility, reduction in joint inflammation associated with both rheumatoid and osteoarthritis with benefits greater than those taking Glucosamine Sulphate.

Additionally, clinical studies have shown TurmaForte® Turmeric to be fast-acting: statistically significant improvement in only 21 days and demonstrates greater efficacy than Glucosamine Sulphate and placebo.

Participants demonstrated a significant reduction in paracetamol use for pain relief.

Suggested Claims Summary ++ May assist with the management of pain associated with inflammation ++ May assist with the symptoms associated with osteoarthritis including pain and inflammation ++ May aid in the relief of symptoms associated with rheumatoid arthritis ++ May act as an anti-inflammatory In vitro (pre-clinical) 1. Chandrasekaran CV, Sundarajan K, Edwin JR, Gururaja GM, Mundkinajeddu D, Agarwal A. Immune-stimulatory and anti-inflammatory activities of Curcuma longa extract and its polysaccharide fraction. Phcog Res 2013;5:71-9.

2. Senthilkumar A, Joshua AJ, Bharathi B, Amit A. (2014) Anti-inflammatory effects of Turmeric (Curcuma longa L.) extracts on acute and chronic inflammation models.

Journal of the Korean Society of Food Science and Nutrition. 43(1): 612-617.

3. Ramanaiah Illuri, Bharathi Bethapudi, Senthilkumar Anandakumar, Sasikumar Murugan, Joshua A. Joseph, Deepak Mundkinajeddu, Amit Agarwal and Chandrasekaran C.V., Anti-Inflammatory Activity of Polysaccharide Fraction of Curcuma longa Extract (NR-INF-02), Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, 2015, 14, 53-62.

4. Bharathi Bethapudi, Sasikumar Murugan, Ramanaiah Illuri, Deepak Mundkinajeddu, Chandrasekaran Chinampudur Velusami. Bioactive Turmerosaccharides from Curcuma longa Extract (NR-INF-02): Potential ameliorating effect on Osteoarthritis Pain. Pharmacogn. Mag, 2017.

5. Chandrasekaran Chinampudur Velusami, Sasikumar Murugan, Prasanna Raja C, Bharathi Bethapudi, Ramanaiah Illuri, Deepak Mundkinajeddu. Anti-arthritic activity of Curcuma longa polysaccharide extract in MIA induced osteoarthritic rats. – Under review.

Safety (pre-clinical) 6. Chandrasekaran CV, Rao BS, Srikanth HS, Edwin JR, Allan JJ, Murali B, Amit A, (2013), Safety evaluation of Turmeric polysaccharide extract: Assessment of mutagenicity and acute oral toxicity. Biomed Research International. 2013: 1-11, article ID 158348.

Efficacy (clinical) 7. K. Madhu, K. Chanda & M. J. Saji, Safety and efficacy of Curcuma longa extract in the treatment of painful knee osteoarthritis: a randomized placebo-controlled trial, Inflammopharmacology (2012).

© 2018 Wild Nutrition Ltd. All information contained in this leaflet is correct at time of print. Wild Nutrition Ltd reserves the right to make changes at any time.

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