Benefits of Beta-Caryophyllene - A Very Common Cannabinoid

Benefits of

Beta-Caryophyllene

Introduction The FDA-approved food ingredient -caryophyllene can activate the endocannabinoid system.

Many plants, perfumes, preservatives, additives, and flavouring compounds all contain it.

Cannabinoid receptor type 1 (CB1) and CB2 receptors make up the endocannabinoid system.

Endocannabinoids including THC and CBD, as well as arachidonic acid, bind nonselectively to both CB1 and CB2 receptors. Cannabis (marijuana) has psychomodulatory effects due to CB1 receptors, whereas CB2 receptors are effective in treating inflammation, pain, atherosclerosis, and osteoporosis.

Beta caryophyllene terpenes binds strongly to CB2 receptors and activates many of the endocannabinoid system's effects.

Reference Link - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2449371/

B enefits of Beta-Caryo phyllene

Helps to Prevent Diabetes High doses of Beta caryophyllene (used orally) may help lower blood sugar levels.

Beta caryophyllene, for example, has been shown to balance glucose levels in diabetic rats, similar to the anti-diabetic medication glibenclamide.

By protecting pancreatic beta-cells from hyperglycemia and improving insulin/glucose signalling, Beta caryophyllene may be able to prevent the development of insulin resistance.

Relieves Pain Beta caryophyllene can enhance natural endorphins and reduce inflammation by targeting the opioid and endocannabinoid systems.

It can also be used topically and locally on painful locations.

Beta caryophyllene can aid in the reduction of muscle spasms and pain.

Can Help Prevent Cancer Beta caryophyllene may aid in the prevention of cancer.

Beta caryophyllene, for example, inhibited tumour growth in mice fed a high-fat diet in an animal research.

If Beta caryophyllene is oxidised, its anti-cancer actions may be enhanced.

By decreasing PI3K, AKT, mTOR, and S6K1 and boosting MAPK, oxidised Beta caryophyllene (CPO) can decrease cancer cell proliferation and cause apoptosis (self-destruction).

Affect on Sex Organs Endometriosis is a condition in which tissue grows abnormally outside the uterine lining.

Beta caryophyllene has been found in animal tests to relieve endometriosis symptoms without impacting fertility.

Beta caryophyllene may operate as a male contraceptive by reducing sperm viability and sperm count in male mice, according to research (but not decreasing overall sperm production).

Treatment of Alcoholism

Beta caryophyllene may be beneficial in the treatment of alcoholism.

Beta caryophyllene treatment, for example, reduced the mice's dependence on alcohol in a research where they were addicted to it.

Alzheimer's Disease Prevention

Beta caryophyllene may aid in the prevention of Alzheimer's disease (AD).

Beta caryophyllene can diminish amyloid beta plaques and immune-induced inflammation in the brain by activating CB2 receptors and upregulating PPAR-gamma, therefore preventing cognitive impairment.

Parkinson's Disease: It Might Help Dopamine deficiency and oxidative stress are characteristics of Parkinson's disease (PD).

Beta caryophyllene inhibits dopamine loss and oxidative stress in the brain via activating CB2 receptors.

Protects The Gastrointestinal Tract

Inflammatory Bowel Diseases may benefit from Beta caryophyllene.

Beta caryophyllene, for example, can lower colon inflammation by activating the CB2 and PPAR-gamma receptors. When coupled with Curcumin, EGCG, or Baicalin, these anti-inflammatory properties can be amplified.

Help To Lower Cardiac Tension Beta caryophyllene protects the brain by reducing neuroinflammation (brain inflammation) and increasing antioxidant levels.

Beta caryophyllene, for example, can raise glutathione levels via activating the Nuclear Factor Erythroid 2-Related Factor 2 (NRF2) pathway, which can protect against glutamate-induced oxidative damage.

Lightens The Skin Beta caryophyllene can reduce melanin synthesis and may help with skin-whitening.

The Vascular System Is Protected

Beta caryophyllene can aid in Vascular Dementia by improving blood flow to the brain (VD).

Beta caryophyllene can also help to lower cholesterol levels (hypercholesterolemia).

Some More Beta Caryophyllene Benefits You Should Be Getting ● Protects May improve Improve Helps May improve May improve May increase longevity

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Conclusion Caryophyllene is one-of-a-kind because this terpene can directly activate cannabinoid receptors, especially CB2.

It’s also known for producing some degree of relaxation and can effectively soothe nervous behavior. This special terp is found not only in cannabis but also in cinnamon, cloves, rosemary, hops, and black pepper. It has a distinct, spicy, warm, peppery flavor and aroma but has hints of gas or fuel when talking about its presence in cannabis strains.

Beta-caryophyllene can cause some potential health-boosting effects, but more research is needed.