Accepted Vaccine and Booster Combinations

COVID-19 VACCINE TABLE 1: EUA APPROVED COVID 19 VACCINE MATRIX - ADMINISTRATION & COMPLIANCE GUIDELINES* Manufacturer / Vaccine Name

Single Dose or Series

Pfizer/BioNTech (Comirnaty®)

2 dose series

Primary Series Verification Allowances (Trojan Check Logic) • 2 matching Pfizer •

mRNA

Moderna (Spikevax)

2 dose series

mRNA

Johnson & Johnson/Janssen

Single dose

1 dose Pfizer and 1 nonmatching dose of any other vaccine approved by the WHO(not Moderna)

•

2 matching Moderna

•

1 dose Moderna and 1 nonmatching dose of Pfizer

•

One dose J&J

Time Frame 2nd dose to be received 3 weeks after 1st; 21-42 days apart

Viral Vector

2 dose series

•

2 matching AZ

•

1 dose AZ and one dose of Pfizer or any other vaccine approved by the WHO(not Moderna)

•

Required 5 months after 2nd dose of primary series

•

Pfizer, Moderna preferred; J&J permitted 2nd dose permitted for age 50 and above 4 months after 1st booster Required 5 months after 2nd dose of primary series

• 2nd dose to be received 4 weeks after 1st

Booster allowed at least 2 mo. after last dose

Viral Vector

AstraZeneca* (Vaxzevria)

Booster

2nd dose to be given 4 – 12 weeks after 1st dose

• •

Pfizer, Moderna preferred; J&J permitted

•

2nd dose permitted for age 50 and above 4 months after 1st booster

•

Required 2 months after 1st dose of primary series

•

Pfizer, Moderna preferred; J&J permitted

•

2nd dose permitted for age 50 and above 4 months after 1st booster

•

2nd dose permitted for age 18 and above 4 months after 1st booster if 1st booster was J and J Required 5 months after 2nd dose of primary series

• • •

Pfizer or Moderna or other WHO approved booster Required 2nd dose permitted for age 50 and above 4 months after 1st booster

Notes

•

Pfizer-BioNTech or Moderna COVID-19 vaccines are preferred over the J&J/Janssen COVID-19 vaccine for primary and booster vaccination due to the risk of serious adverse events. May be considered in some situations

•

If patient has received nonapproved booster, wait 28 days before administering Pfizer booster If Pfizer booster received < 5 months after 2nd dose of primary series consider fully boosted and do not revaccinate

•

Covishield™*

2 dose series

Viral Vector

Sinopharm/BIBP*

2 dose series

Inactivated Virus

•

2 matching Covishield

•

1 dose Covishield and one dose of Pfizer or any other vaccine approved by the WHO(not Moderna)

•

2 Sinopharm-BIBP

•

1 dose sinopharm and one dose of Pfizer or any other vaccine approved by the WHO(not Moderna)

2nd dose to be received 6 – 8 weeks after 1st dose

2nd dose to be received 3 – 4 weeks after 1st dose 21- 28 days apart

•

Required 5 months after 2nd dose of primary series

•

Pfizer or Moderna or other WHO approved booster Required

•

2nd dose permitted for age 50 and above 4 months after 1st booster

•

Required 5 months after 2nd dose of primary series

•

Pfizer or Moderna or other WHO approved booster Required 2nd dose permitted for age 50 and above 4 months after 1st booster

•

Sinovac* (CoronaVac)

2 dose series

Inactivated Virus

Covaxin®*

2 dose series

Inactivated Virus

Covovax™*

2 dose series

•

2 matching SinovacCoronaVac

•

1 dose sinovac and one dose of Pfizer or any other vaccine approved by the WHO(not Moderna)

•

2 matching Covaxin

•

1 dose Covaxin and one dose of Pfizer or any other vaccine approved by the WHO(not Moderna)

•

2 matching Covovax

2nd dose to be received 2 – 4 weeks after 1st dose; 14 - 28 days

2nd dose to be received 4 weeks after 1st dose; 28 days

2nd dose to be received 3-4

•

Required 5 months after 2nd dose of primary series

•

Pfizer or Moderna or other WHO approved booster Required

•

2nd dose permitted for age 50 and above 4 months after 1st booster

•

Required 5 months after 2nd dose of primary series

•

Pfizer or Moderna or other WHO approved booster Required

•

2nd dose permitted for age 50 and above 4 months after 1st booster

•

2nd dose permitted for age 50 and above 4 months after 1st booster

•

Required 5 months after 2nd dose of primary series

•

•

•

•

•

•

•

•

•

If patient has received nonapproved booster, wait 28 days before administering Pfizer booster If Pfizer booster received < 5 months after 2nd dose of primary series consider fully boosted and do not revaccinate

If patient has received nonapproved booster, wait 28 days before administering Pfizer booster If Pfizer booster received < 5 months after 2nd dose of primary series consider fully boosted and do not revaccinate If patient has received nonapproved booster, wait 28 days before administering Pfizer booster If Pfizer booster received < 5 months after 2nd dose of primary series consider fully boosted and do not revaccinate

If patient has received nonapproved booster, wait 28 days before administering Pfizer booster If Pfizer booster received < 5 months after 2nd dose of primary series consider fully boosted and do not revaccinate

If patient has received nonapproved booster, wait 28

• Protein Subunit

Nuvaxovid™* (Novavax)

2 dose series

•

2 matching Novavax

•

1 dose Novavax and one dose of Pfizer or any other vaccine approved by the WHO(not Moderna) 1 dose Convidecia

Protein Subunit

CanSino-Convidecia

1 dose series

1 dose Covovax and one dose of Pfizer or any other vaccine approved by the WHO(not Moderna)

•

weeks after 1st dose; 21-28 days

•

Pfizer or Moderna or other WHO approved booster Required

•

2nd dose permitted for age 50 and above 4 months after 1st booster

2nd dose to be received 38weeks after 1st dose; 21-42 days

•

Booster not currently recommended.

Not approved for use as a booster.

N/A

•

•

• Viral Vector Non-WHO Approved Vaccines: Sinopharm WIBP, CoviVac, EpiVacCorona, Sputnik V

•

Restart primary series with approved vaccine Pfizer/Moderna/J&J

28 days after last dose of nonapproved series

•

Required 5 months after 1st dose of primary series Pfizer or Moderna or other WHO approved booster Required Required after restarting primary series with approved vaccine (follow guidelines for series above)

*guidelines are for individuals NOT at increased risk due to moderate or severe immunocompromised The following FDA-approved (emergency use authorization, EUA and FDA approved) vaccines are accepted for meeting COVID-19 vaccine requirements:

Pfizer/BioNTech (Comirnaty®) — 2 doses Moderna (Spikevax) — 2 doses Johnson & Johnson/Janssen — single dose Novavax (Nuvaxovid™) – 2 doses

The following WHO-approved (emergency use listing, EUL) vaccines are accepted for meeting COVID-19 vaccine requirements:

AstraZeneca* (Vaxzevria) Covovax™* Covishield™* Covaxin®* Sinovac* (CoronaVac) Sinopharm/BIBP* CanSino-Convidecia

Non EUA Approved Vaccines: Sinopharm WIBP, CoviVac, CanSino-Convidecia, EpiVacCorona, Sputnik V

For Trojan Check compliance logic, go to: https://eshc-w2.usc.edu/display/IS/Trojan+Check

•

days before administering Pfizer booster If Pfizer booster received < 5 months after 2nd dose of primary series consider fully boosted and do not revaccinate