Minds Conquering Cancer Magazine, Issue 3

GROUNDBREAKING RESEARCH + EFFECTIVE OUTREACH + EXCEPTIONAL PATIENT CARE Fall 2015

A Publication of the University of South Alabama Mitchell Cancer Institute

STORY: + SURVIVOR April Boone Noted DNA + Researcher

Joins MCI

+ Rose Garden Gift

+ Dr. Michael Finan Spearheads

Ambitious

Plan

AROUND THE INSTITUTE

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1660 Springhill Avenue • Mobile, Alabama 36604

Director Michael A. Finan, M.D.

Administration Laurie Owen, Ph.D. Margaret Sullivan

MCI Physicians Thomas W. Butler, M.D. Daniel G. Cameron, M.D. David R. Clarkson, M.D. Michael A. Finan, M.D., F.A.C.S. Moh’d Khushman, M.D., F.A.C.P. Carole Wiseman Norden, M.D. Rodney P. Rocconi, M.D. John R. Russell, M.D. Jennifer Scalici, M.D. William R. Taylor, M.D. Mary Vu, M.D.

From the Director Dear Friends,

I

The cancer battle is far from over, but new insights made possible by research are enabling continued progress against cancer. The availability of safer and better treatments has contributed to increased survival rates and improved quality of life for patients. Our early detection team works tirelessly on development of new screening tests for pancreatic and ovarian cancers.

USA/MCI Member Physicians Jack DiPalma, M.D. D. Lynn Dyess, M.D. Lee Grimm Jr., M.D. Curtis N. Harris, M.D. Hamayun Imran, M.D., M.Sc. Shikha Khullar, M.D. Spencer Liles, M.D. Anthony Martino, M.D. Allen Perkins, M.D. William Richards, M.D. Paul Rider, M.D. Hafeez Siddiqui, M.D. ra te er M Marcus Tan, MBBS (Hons) Joshua Taylor, M.D Zhiqing Xing, M.D.

ON THE COVER GROUNDBREAKING RESEARCH + EFFECTIVE OUTREACH + EXCEPTIONAL PATIENT CARE Fall 2015

A Publication of the University of South Alabama Mitchell Cancer Institute

STORY: + SURVIVOR April Boone Noted DNA + Researcher

Joins MCI

+ Rose Garden Gift

+ Dr. Michael Finan Spearheads

Ambitious

Plan

New Director Dr. Michael Finan heads up a team of nearly 300 clinicians, researchers and staff in t e t against cancer.

t is an exciting time at the Mitchell Cancer Institute as we continue our mission to serve as the pre-eminent cancer care, research and educational institution in the Gulf South.

Dr. Michael A. Finan

We consider ourselves on the front line of this complex and often baffling disease, and in this magazine you’ll read about MCI’s efforts in research, outreach and treatment. Earlier this year, we welcomed internationally renowned researcher Dr. Robert W. Sobol as chief of the molecular and metabolic oncology program. This program focuses on the promising area of cellular mechanisms of DNA repair and metabolism and how they impact cancer development and treatment. Husband and wife scientists Drs. Ajay and Seemah Singh are also featured with their promising research into pancreatic and prostate cancer as well as melanoma.

We have launched a five-year strategic plan to be a National Cancer Institute-Designated Comprehensive Cancer Center by 2020 through a consortium partnership between MCI and the University of Alabama at Birmingham. This designation will allow us additional resources, as well as access to further funding and clinical trials.

Funding continues to be the life’s blood of the research that provides hope and cuttingedge treatment to our patients. While competition is fierce and funding limited, two of our researchers, Dr. Yaguang Xi and Dr. Gary Piazza, recently received prestigious R01 research grants from the National Cancer Institute at the National Institutes of Health in colorectal and colon cancer.

Our research is motivated each and every day by the patients who seek care at our facility. Through our oncology care teams, we aim to deliver the highest level of patient care. Our outreach efforts have provided education and accessible cancer screening to those in our community.

We thank you for your support in our mission to vanquish cancer through transformative research, education and health care. The battle rages on, but every day brings us a little closer to a cure.

Sincerely,

Dr. Michael A. Finan

Director, USA Mitchell Cancer Institute

Minds Conquering Cancer | Fall 2015

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AROUND THE INSTITUTE MCI represents a total investment of over $135 million, including $85 million in construction and equipment.

At A Glance

USA Mitchell Cancer Institute In t e

t a ainst an er not in s oul be

MCI represents the largest single research endeavor in the history of the University of South Alabama, with a total investment of over $135 million, including $85 million in construction and equipment.

left out. Everything matters. The leading-edge research. The state-of-the-art clinical services.

The commitment to new screening tools, new

MCI faculty and staff total approximately 300 employees, with continuous recruitment of clinical faculty and funded researchers underway.

treatments and new prevention techniques. It is t e ombine e orts o all t e min s in t is battle scientists, physician specialists, primary physicians, and, yes, patients – that make the difference. This is why USA Mitchell Cancer Institute (MCI) focuses on the entire package of care. With a strategic oal o be omin a

ational Can er Institute

Designated Comprehensive Cancer Center, MCI’s researchers and clinicians stand on the front lines in t e battle a ainst an er MCI ta es ri e in t e

Oncology teams at MCI include seven medical oncologists, two radiation oncologists and three gynecologic oncologists. Together with three pediatric oncologists within the USA Department of Pediatrics and six surgical oncologists within the USA Department of Surgery and others in the community, care is provided in a multidisciplinary team approach. In addition, MCI has over 33 associate, affiliate and member physicians within the service area.

accomplishments of our physicians, researchers and patients, and looks toward a progressive future of innovation that advances cancer treatment in our re ion an be on

MCI is t e onl a a emi

base

an treatment a ilit in t e

an er resear

sout ern art o

labama an t e entire u

Coast region.

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Minds Conquering Cancer | Fall 2015

er

ul

The 150-mile radius service area of MCI consists of over 4.1 million people.

MCI clinical areas include a state-of-the-art radiation oncology department with the full continuum of radiation oncology modalities including a CyberKnife Stereotactic Radiosurgery System and a TomoTherapy System.

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In 2014, more than 2,900 new patients were treated at MCI, generating more than 50,000 patient visits.

The MCI Medical Oncology Division also operates clinics in Fairhope and Monroeville, providing easy access to patients in Baldwin and Mobile counties.

The USA Health System includes the USA Medical Center and USA Children’s & Women’s Hospital, both academic tertiary specialty hospitals.

The MCI cancer research enterprise includes 12 principal investigators/individual laboratory heads, 14 postdoctoral trainees, eight graduate student trainees and over 27 specialized laboratory support staff. As of January 2015, all 12 principal investigators are funded.

The MCI research infrastructure consists of established core laboratory facilities in the areas of flow cytometry, advanced imaging, genomics, proteomics, pathology, tissue biobank and drug discovery. These phenomenal core laboratories provide the infrastructure to enable MCI researchers and other USA researchers to be competitive for peer-reviewed grants, as evidenced in our rapidly increasing grant portfolio.

Cumulative extramural grant funding exceeds $18.3 million. On average, each principal investigator has $1.8 million in grant funding. Annual extramural grant funding exceeds $4.2 million.

To date, intellectual property emerging from MCI has resulted in the filing of more than 45 patent applications as well as the startup of at least five companies: Swift Biotechnology, Creatics, ADT Pharmaceuticals, PDEi Pharmaceuticals and Tatva Biosciences.

A Publication of University of South Alabama Mitchell Cancer Institute

Give the

Gift of Hope USA Mitchell Cancer Institute brin s o e to t ousan s alon t e ul Coast b ma in a si ni ant difference in the prevention, diagnosis and treatment of cancer. But hope doesn’t just ome rom it in our buil in It comes from our entire community. People just like you.

When you make a gift to MCI, ou be ome an im ortant stakeholder in our mission and help provide hope to those suffering from cancer.

One hundred percent of your donation supports cancer research or patient services at MCI. For more information, contact Kelly McCarron, Director of Development, MCI, at 251-445-8423 or kmccarron@southalabama.edu.

FREE

Subscription Minds Conquering Cancer

In 2013, MCI and the University of Alabama at Birmingham (UAB) Comprehensive Cancer Center entered into a declaration of intent to establish a Cancer Center Consortium. Research collaborations are underway that will ultimately improve cancer outcomes and reduce cancer health disparities for the citizens of Alabama.

To learn more about MCI visit www.usamci.com

A Publication of University of South Alabama Mitchell Cancer Institute

or a ree subs ri tion to MCI’s Minds Conquering Cancer, please call Victoria Lassiter at 251-445-9677 or send an email with your name and address an re uest or a ree subs ri tion to vlassiter@health.southalabama.edu.

Minds Conquering Cancer | Fall 2015

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fall 2015 ISSUE 1 • VOLUME 3

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Noted Researcher Joins MCI

Survivor Story April Boone

FEATURES

24 New Director Spearheads mbitious lan

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Minds Conquering Cancer | Fall 2015

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Patient Gift Creates Beautiful Setting

Table of Contents

AROUND THE INSTITUTE

3 4 8 10 12 12 13 13 47

Letter from the Director At a Glance Goodwill Ambassador Dottie Perkins New Doctors In Remembrance: Kathy Eslava Chamber Award: Lynne Chronister Monroe County Partnership Fairhope Expansion Calendar of Events

RESEARCH 18 22 23

Seema and Ajay Singh Xi Receives NIH Grant Piazza Grant to Develop New Drugs

TREATMENT 28 29 30

GI Doctors Part of Team Approach Lay Navigation Nurse Survivor Susan Hofelich

OUTREACH 34 35 38 39 40

Sew & Sow Ministry Colorectal Cancer Outreach Breast Cancer Survivor Group Oncology Outlook Survivors Day

DEVELOPMENT 41 42 44 45 46

Donor Profile: Cindy Manderson Celebrate Hope 2014 Think Pink 2014 Point Clear Charities GO Run 2014

A Publication of University of South Alabama Mitchell Cancer Institute

EDITOR Meredith Portman

WRITERS Meredith Portman Kristal Sheets

PHOTOGRAPHERS Colette Boehm Vincent Calhoun Bill Starling

CREATIVE DIRECTORS Laura Burton Andy Zak -

PRINTING niversit o out labama ubli ation ervi es

Produced in cooperation with the University of South Alabama Office of Marketing and Communications

Minds Conquering Cancer | Fall 2015

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AROUND THE INSTITUTE

Dottie

PERKINS MCI’S GOODWILL AMBASSADOR

W

hen patients approach the front entrance of C often the first thing they see is the smiling face of ottie Perkins and Lulu, an oversize stuffed animal in the shape of a green worm perched atop the valet stand.

Since 2010, Dottie has been a friendly part of the MCI family, heading up valet services. As for the worm, Lulu was a gift from a patient who was successfully treated at MCI four years ago.

Dottie encourages patients to rub the worm for good luck.

Personal touches are Dottie’s specialty. While parking cars is part of her job in valet services, taking care of patients is an equally important function. Sometimes this involves helping them find their appointment location, retrieving a blanket if they’re cold, or getting them a snack or drink, often at her own expense.

“Valet is a lot more than parking cars,” she explained.

“We try to do everything we can to make a patient comfortable and happy.”

Dottie was originally hired more than six years ago to work in housekeeping, but she soon found her niche in valet services, where she is part of a three-person team. To say she is a people person would be an

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Minds Conquering Cancer | Fall 2015

understatement. She loves her job and says she doesn’t like to miss a day because she’s afraid she’ll miss out on a hug or a smile.

“The patients here are special to me,” she said.

“When I see somebody that’s not feeling well, maybe they’ve gotten some bad news, I just give them a hug and tell them I love them.

Sometimes that’s the best medicine.”

Her warmth means a lot to James Tucker, 84, who recently waited in the lobby for his wife while she was being treated in the chemotherapy infusion suite.

“The valet service is very valuable to us,” he said.

“Neither one of us is able to walk very well from the parking lot, so it helps us a lot. And Dottie will do anything for us. If this service wasn’t here, it would be really hard for people our age.”

Dottie believes her job has a higher purpose.

“I think God put me here because I have so much love to give,” she said.

“Valet is a lot more than parking cars. We try to do everything we can to make a patient om ortable an a

Minds Conquering Cancer | Fall 2015

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AROUND THE INSTITUTE

Welcome

NEW DOCTORS MCI’S NEWEST TEAM MEMBERS New Surgeon

Dr. Joshua Taylor Dr. Joshua Taylor has recently joined the staff of the University of South Alabama College of Medicine as an assistant professor of surgery.

A native of Mount Vernon, Ala., Dr. Taylor earned a medical degree from Johns Hopkins University School of Medicine in 2010. He recently completed his residency in general surgery at Vanderbilt University Medical Center.

Dr. Taylor is board eligible for the American Board of Surgery. His research on neoadjuvant chemoradiation and surgery has been presented at national symposiums and has appeared in several publications.

Dr. Taylor’s clinical interests include benign and malignant diseases of the breast, stomach, small intestine and colon, and endocrine diseases of the thyroid, parathyroid, and adrenal gland. Advanced minimally invasive laparoscopic surgery including reflux disease, hernias, and gastrointestinal surgery are among his specialties.

At Vanderbilt, Dr. Taylor received the Society of Thoracic Surgeons Looking to the Future Scholarship and at Johns Hopkins, the William Stewart Halsted Award in Surgery. As an undergraduate, Dr. Taylor was a walk-on defensive back for the University of Alabama football team. He is a member of the MOWA Band of Choctaw Indians of South Alabama.

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Minds Conquering Cancer | Fall 2015

New Medical Oncologist

New Surgeon

Dr. Moh’d Khushman was recently appointed as an assistant professor of interdisciplinary clinical oncology and staff medical oncologist at the University of South Alabama Mitchell Cancer Institute. Dr. Khushman holds a joint academic appointment in the Department of Medicine within the USA College of Medicine.

Dr. Spencer Liles, a surgical oncologist, has joined the staff of Mitchell Cancer Institute and the University of South Alabama College of Medicine as an assistant professor of surgery.

Dr. Moh’d Khushman

Prior to this position, Dr. Khushman completed his fellowship in hematology-oncology at the University of Miami Leonard Miller School of Medicine. Among a wide spectrum of malignancies, Dr. Khushman developed a clinical interest in GI malignancies (pancreatic, hepatobiliary, colorectal, anal, gastric and esophageal) and breast cancer. During his fellowship, he explored the role of identifying potential predictive markers to mTOR pathway targeted therapy in pancreatic neuroendocrine tumors.

Dr. Khushman is a member of the American Society of Clinical Oncology, The European Society for Medical Oncology and the American Society of Hematology.

He earned his medical degree from The University of Jordan in Amman, and completed his residency in internal medicine at Henry Ford Hospital in Detroit, where he served as a chief medical resident.

Dr. Khushman sees patients at the Mitchell Cancer Institute in Mobile and Fairhope.

Dr. Spencer Liles

Dr. Liles completed his fellowship in complex general surgical oncology at the University of Texas MD Anderson Cancer Center in Houston. He is boardcertified by the American Board of Surgery and is a member of the Society of Surgical Oncology and the American College of Surgeons.

His clinical interests include breast, endocrine and gastrointestinal malignancies, as well as melanoma. Dr. Liles has authored numerous articles and abstracts on pancreatic adenocarcinoma, sarcoma and rectal cancer.

A native of Birmingham, Dr. Liles earned his medical degree from the University of Alabama School of Medicine and completed his residency training in general surgery at the University of Alabama at Birmingham. During his residency, Dr. Liles received a National Institutes of Health T32 Research Training grant allowing him to complete an additional three years of basic science research, during which he focused on eliciting several molecular pathways driving pancreatic adenocarcinoma.

Minds Conquering Cancer | Fall 2015

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AROUND THE INSTITUTE

In emembran e

KATHY ESLAVA Kathy Eslava, a longtime fixture at MCI, passed away on Nov. 8, 2014, after a battle with breast cancer. “Kathy’s smile and love of life were infectious. She was a friend to everyone at MCI and is missed terribly. From organizing staff to sing as carolers during the holidays to her can-do attitude and empathy for patients, she found joy in giving to others,” said Margaret Sullivan, deputy director for business development and outreach at MCI, and Eslava’s supervisor.

Eslava was an employee of the University of South Alabama for nearly 25 years. In addition to working in administration at MCI for the past three years, she worked in the radiation oncology department for 20 years.

“She had a big heart. She would always go out of her way for others.”

It was there that she met Greg House, for whom she became a second mom. As former director of radiation oncology, he worked with Eslava for 13 years. “Even though she was my employee, she was like family,” he said. “As an employee she was wonderful, reliable, always positive. Plus, she never met a stranger. It didn’t take long before she would end up hugging you.”

Eslava’s friendly nature was an asset at the radiation oncology clinic, where she developed a genuine rapport with patients.

Outside of work, she was a fixture at fundraisers like the American Cancer Society Chili Cookoff and Breast Cancer Walk.

“She had a big heart. She would always go out of her way for others,” said House.

Eslava is survived by her daughter Jennifer Mallette, son Derek (Jo Lynn) Mallette, and grandchildren Joel, Jake, Riley and Avery.

In memory and honor of Eslava, MCI scientist Steve M Clellan as establis e

t e at

slava Can er

Stem Cell Endowment. For more information, contact MCI Director of Development Kelly McCarron at or m

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arron sout alabama e u

Minds Conquering Cancer | Fall 2015

CHRONISTER HONORED WITH INAUGURAL CHAMBER AWARD Lynne Chronister was recently onore it t e rst ever Catal st ar iven b t e Mobile rea C amber o Commer e The award was presented to C ronister or er abilit to ste up, to lead, to manage, to make t in s a en a or in to boar C airman Mi ael C ambers She has accomplished this not only in her capacity as vice president for research and economic development at the University of out labama a osition s e as el sin e but also t rou er involvement it t e amber an t e Mobile business ommunit At USA, Chronister oversees research growth across the institution, including interdisciplinary research efforts, resource development and orchestration of all phases of research administration. This includes working with the activities of Research Compliance, Sponsored Projects Administration, Research Development, the Center for Commer iali ation an In ustr Collaboration and the Mitchell Cancer Institute. e as also been a tive in brin in to et er t e lea ers i at an t e Mobile business community. USA President Tony Waldrop raises C ronister s lea ers i abilit it in the University system, citing her work as “an outstanding example of how the University working with community organizations and businesses lea s to su ess C ronister believes t at t is su ess is a s are e ort T e oo eration bet een t e area s business industry and nongovernmental entities, as ell as t e it ount an t e Mobile rea C amber is unusuall oo erative s e sai Chronister formerly served as assistant vice provost for research and director of sponsored programs at the University of Washington. She previously worked at USA, serving as associate director of sponsored programs from 1988 to 1992 and earned her master’s degree in ubli a ministration rom t e niversit e ol s a ba elor o arts in s olo rom t e University of Vermont.

Jeff Brannon, CEO at Monroe County Hospital and Dr. Michael Finan, Director of the USA Mitchell Cancer Institute signed the agreement.

Partnership Brings Comprehensive Cancer Care to

MONROE COUNTY

USA Mitchell Cancer Institute has partnered with Monroe County Hospital to bring advanced cancer care to Monroe County and surrounding areas.

focused activities in colon and breast cancers. Dr. Clarkson has distinguished himself in private practice as one of the leading medical oncologists in the region, with a specialty in hematology and lymphomas.

Starting in May, MCI medical oncologists Dr. Daniel G. Cameron and Dr. David Clarkson began providing services on a rotating basis to cancer patients at the hospital’s Oncology Clinic. This allows local patients access to quality specialty care without having to travel long distances.

“We believe this new relationship will enhance our ability to provide comprehensive cancer care due to Mitchell Cancer Institute’s capabilities,” said Monroe County Hospital CEO Jeff Brannon. “We are excited about this opportunity for patients to receive great care right here at home.”

“Great things are happening at the USA Mitchell Cancer Institute,” added MCI Director Dr. Michael Finan. “Together, through our team of clinicians, scientists and member physicians, we will continue to make significant strides in improving cancer outcomes for the people of Monroe County, south Alabama and the Gulf Coast region.”

Dr. Cameron and Dr. Clarkson are senior staff physicians at MCI. Dr. Cameron has extensive experience in all hematology and oncology diseases, with special interests in clinical research and clinical

PROFESSIONAL OFFICE BUILDING UNDER CONSTRUCTION A new USA Physicians Group professional o e buil in is ta in s a e a ross rom C il ren s omen s os ital T e buil in ill be t e ne lo ation or a lar e ortion o the USA Physicians Group practice including eneral e iatri s e iatri subs e ialties obstetri s an ne olo ort o ae i s an ort o ae i re abilitation neuros ien es an an illar are T e s a e ill ontain a breast and mammography center and clinical space or relate on olo are rovi e b a ult and staff from the Mitchell Cancer Institute.

Minds Conquering Cancer | Fall 2015

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l u f k n tha o t g o l b o t s n r u t survivor ancer journey c e l c i n o chr

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Minds Conquering Cancer | Fall 2015

s t e o ner o lobal Ma r etin oluti in ole ons ril oone is in t e business communica o tion. Still, wh en trying to decide o ort om in s e ou l be about breast an er er ia nosis it ave er ause A patient of MC

I oncologist Dr. Daniel Ca sta e I u ta meron, Boon l ar inoma e was diagn in situ in er osed with le t breast in e a a lum u ust e tom an a t t ea eo in sim le treatm tober s e be ent lan t a an at s e t ou t in lu e t as a ra iation sess ions it a ba roun as a riter s e on experience, si ere start feeling it wa in a blo a s a natural e bout er xtension of w some on e rns about riv ho she was.

But she did h a ave I o ne a b usiness an t at oul ut me in a ersonal in orm ubli settin ation t at ra s arin n l some i l eo le i n t ant to no s e sai ut ultimatel oone e i e to la u n is el some o er blo boo t e i noran nes orl om to e bot er asso iate o n a n t at o ot e it breast a rs s e elt n er an its as treatment It eal it also be am at be ame e an outlet to a tumultuou s an er ou rne Minds Conquering Cancer | Fall 2015

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The simple treatment plan Boone had imagined did not go as she had planned, which is not uncommon for patients. But she was also taking the medication methotrexate for rheumatoid arthritis, which made her susceptible to side effects from the radiation. She also experienced tremendous fatigue.

She went off the methotrexate, soldiered on and finished her radiation treatments right in time for Christmas in 2012.

the fateful letter In February 2013, Boone went for her first follow-up mammogram. The following Saturday, she received a letter from the hospital stating that something had been detected on her left side.

On Monday, she had an appointment with Dr. Cameron and asked his recommendation based on the data.

The lumpectomy had already removed a substantial amount of tissue, and the new report was ominous. He recommended a bilateral or double mastectomy.

“I’ll never forget he said ‘the data is not in your favor,’” she recalled. “For me, that was what I needed to hear.

That’s what I appreciate most about Dr. Cameron. He doesn’t have an agenda. He gives you the information you need, but ultimately follows your lead.”

Since only the left breast was affected, her surgeon was not on board with the double mastectomy, nor was her insurance company. Then, in March 2013, an MRI revealed a questionable area in her right breast. She went to a plastic surgeon and tried again for insurance approval. At one point, she launched a gofundme.com drive to make up the $5,000 difference in what was to be her down payment on her surgery.

She appealed, waited and took to her blog. It proved to be cathartic. “I felt like it was something I could control,” she said.

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Minds Conquering Cancer | Fall 2015

Aug. 3, 2013 So next week…I continue on with oneear tests I ontinue tin m insuran e om an I ontinue orr in about m ealt mone m business m love ones Can er ee s tr in to beat me an ta e me down, one little piece at a time. But I’m still standing. So each day, I say, To a I on

While Boone received a lot of positive feedback from her blog, particularly from patients going through cancer, not everyone was a fan, including her closest friends. Some felt she needed to get over it and move on. Others just disappeared.

“One thing you learn,” she said philosophically, “not everyone is going to go all the way with you on your cancer journey.”

One person who never left her side was her husband of 25 years and business partner, John, who has his own health concerns. Diagnosed with multiple sclerosis a decade ago, he was a constant source of strength and support for Boone.

business an t in but usual After six months, Boone got approval to proceed with the mastectomy. But she had complications on both sides, infections that were in part caused by her lowered resistance due to the methotrexate, which resulted in four surgeries between August 2013 and February of 2014.

“John and I had been through a lot already healthwise, but the breast cancer just really knocked me down.

I kept thinking, “Why is this not a breeze for me?

It’s supposed to be. I felt like I was failing cancer treatment,” she said, laughing.

While dealing with her own health issues, Boone was also managing a business with 12 employees.

Increasingly, she had to lean on her team. In 2013, she hired a manager to take over some of her duties.

Her openness on her blog caused a few clients to question her company’s ability to continue to provide services. That was when Boone would get out of bed, attend meetings and assuage their fears. “But you know, it’s business, and clients have to know they’re going to be taken care of by the vendor they hired,” she said.

As a testament to the resilience of both Boone and her team, the company experienced double-digit growth in 2013 and 2014.

The spring of 2014 brought another issue: lymphedema, which is swelling caused by the removal of or damage to lymph nodes as part of cancer treatment that usually occurs in the arms and legs. For Boone, it was present

ov “So am I thankful today? Oh, and how. I am thankful I can sit in a warm room with an expensive computer and type these words…

Thankful I can eat real food today, not food from a dumpster or an IV … Thankful I’m looking right at someone who loves me no matter what. Thankful for my medical team, working to get me to the place where I can see t at over o in lass a ain an not roan be ause it s me i ine I ave to ta e Thankful. Eternally thankful. oone and her dogs Tob an Te

in her head, both arms, back, hands and wrists. It cannot be cured, but only managed through therapy.

Today, Boone is managing her lymphedema, and in spite of a year in which she achieved “nothing but survival,” she is cautiously optimistic about the future and still able to find moments of grace.

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RESEARCH

AJAY AND SEEMA SINGH:

Collaborators in Work and Life Like many married couples, Mitchell Cancer Institute researchers r jay ingh and r eema ingh finish each other’s sentences, partic larly when yo get them on the subject of cancer – a career path and passion they both share.

Since coming to MCI in 2009, the in s ave oun Mobile to be fertile ground for their respective research, as well as a good place to raise their family.

In 2008, Ajay, a researcher at the niversit o ebras a in is ei t year, was restless and the cold weather had taken its toll. After earin about a ne an er resear enter in Mobile e sent an email to Dr. Mike Boyd, former director of MCI, who responded immediately to his inquiry.

With two recent grants under is belt rom t e e artment of Defense and the National Institutes of Health (NIH), Ajay, whose research focus areas include pancreatic and prostate cancer, was ready

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Minds Conquering Cancer | Fall 2015

for a move. Seema, a skilled researcher in her own right, had research interests in melanoma, an reati an breast cancer that dovetailed perfectly into MCI’s longterm plan.

In 2009, Dr. Laurie Owen re ruite t e usban wife team.

To the Singhs, MCI represented opportunity, with a state-of-theart facility, and the ideal setting to buil somet in ne an e an on their research areas.

“When I came here, there was so mu momentum to buil MCI said Ajay. “They really wanted to e an an un it In some a s Mobile also reminded them of home.

Mobile is more li e In ia at least eat er ise eema note Ajay is an associate professor and Seema is an assistant professor in the department of oncologic sciences at MCI. While they are bot resear ers t e onsi er t emselves more ollaborators than competitors. In fact, if one serves as principal investigator on a grant, the other is frequently a co-investigator, and vice versa.

“We complement each other with our specialty, and not just as usban an i e sai eema “We understand each other very ell a a e T e ou le as been ettin a lot o ra ti e latel at ollaboration as t e ave been su ess ul at getting grants to fund their research.

In a re eive a million ve ear rant rom t e National Cancer Institute (NCI) to study the causes of racial disparities in prostate cancer, which affects African-American men disproportionately. He also received a grant from the labama e artment o ubli Health to study the molecules and mechanisms facilitating tumorstromal cross-talk in prostate cancer. Seema serves as a coinvesti ator on bot rants

In t e el o an reati an er resear in a re eive a resti ious million ve ear R01 grant from the NIH to advance research in t e t a ainst an reati an er s e i all targeting tumor-stromal interaction for therapy.

abilities o silver nano arti les to rote t s in rom ultraviolet radiation that causes skin cancer. Seema an er team i in lu es a ill also be researching economic and eco-safe methods to create synthetic silver nanoparticles.

That same year, Ajay was also a co-investigator on a rant rom t e ational ien e Foundation to acquire transmission electron mi ros o es or t e niversit o out labama

Her research has sparked the development of a company called Tatva Biosciences. The word tatva means element in ans rit ur lon term goal is to take this project and commercialize it to ma e reams an lotions s e sai

Ajay received an R21 NIH grant for pancreatic cancer in 2012, a grant that received a percentile of 1.0 with a perfect score, meaning that the whole grant panel gave it a top score.

As for Seema, in 2012, she received a two-year grant from the NIH/NCI to investigate the role of the protein ETV4 in pancreatic tumor cell growth and metastatic potential, and assess its incidence and association with tumor aggressiveness in clinical specimens. Ajay serves as co-investigator.

Seema is also currently serving as a co-investigator on a MCI grant that will examine the role of FAK mediated proteins in melanoma metastasis, using eneti mouse mo els an in ibitors Her most promising work stems from a grant she received from NCI to explore the chemopreventive

he inghs

it t eir t o au

ters ast a an

ub a

T is urr o i level un in is in i ative o t e overall push at MCI to advance cancer research and raise grant-funding dollars for cancer-related research.

T ere as been tremen ous e onential ro t in the amount of money MCI had for research when we came here versus the amount of money we ave no sai a Ajay and Seema met as students at Aligarh University in Aligarh, Uttar Pradesh, India, in 1995.

Married since 2000, the Singhs have two daughters, 11 and 5 years old. The oldest daughter is intereste in s ien e an ants to be a si ian t ome t e in s are also ollaborators it Seema assuming more of the childcare duties, ile a s ob is to ee t e il ren a Their culture is an important part of their family life.

T e are ra ti in in us an members o t e In ian sso iation o reater Mobile ile t eir religion recognizes most traditional U.S. holidays like Christmas, others are unique like Holi, the festival of olors t at eral s t e arrival o s rin elebrate b t ro in a ets o olor on arti i ants An accomplished cook, Seema recently displayed her skills at the American Cancer Society’s Chili CookOff, serving as head chef of MCI’s team. Her Indian vegetarian chili was the team entry in the contest. ot in s are en oura e about t e ro t MCI as e erien e sin e t e arrive an t e re rati e to be a van in an er resear ere in Mobile e li e it ere sai a e ante to ome somewhere where we could make a mark. We felt i e reall ante to ontribute to s ien e e oul o it better ere

Minds Conquering Cancer | Fall 2015

19

Noted Cancer Researcher

Joins Mitchell Cancer Institute

D

r. Robert W. Sobol has joined the faculty of the Mitchell Cancer Institute as the chief of the Molecular & Metabolic ncology program e will also ser e as the Point Clear Charities Professor of ncologic ciences and an braham itchell isting ished n estigator

The Molecular & Metabolic Oncology program will focus on the cellular mechanisms of DNA repair and metabolism and how these processes impact cancer development and the response to cancer treatments.

Serving as program director, Sobol will work with eight labs, including his new lab, two current MCI labs and five others to be added over the next three years.

“We are delighted that Dr. Sobol has chosen MCI as his destination to build a world-class program in DNA damage and repair,” said Dr. Laurie Owen, associate director of basic and translational sciences at MCI. “Rob is an internationally renowned scientific researcher recognized for his passionate commitment to translational research.”

DNA repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. Abnormalities in these repair processes have been implicated in cancer and aging as well as the response to chemotherapy and radiation.

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Minds Conquering Cancer | Fall 2015

At MCI, Sobol plans to launch a biotech company, Canal House Biosciences, to develop and evaluate small molecules to inhibit DNA repair and enhance chemotherapy and radiation treatments by disrupting key protein complexes. His research has already led to the formation of one company, Paradigm Oncology.

“The Mitchell Cancer Institute is a great resource here in this community,” said Sobol. “Our hope is that we will continue this mission and advance it to the point where treatments and therapies could be effectively tailored to each patient.”

Sobol came from the University of Pittsburgh, where he served as associate professor in the Department of Pharmacology & Chemical Biology and the Department of Human Genetics. In addition, Sobol was a scientist in the University of Pittsburgh Cancer Institute, where he was a member of the Molecular and Cellular Cancer Biology program, director of the Lentiviral Facility and co-director of the Vector Facility. Last year, he was a visiting lecturer in DNA repair at Sichuan University in Chengdu, China.

His research has been recognized with grants from the American Cancer Society, the National Institutes of Health and the Susan G. Komen Breast Cancer Foundation, among others.

A graduate of Allegheny College in Meadville, Pa., Sobol received his M.A. and Ph.D. from Temple University in Philadelphia.

hro gh research into

repair

r obol believes treatments an t era ies an be e e tivel tailore to ea

atient

Minds Conquering Cancer | Fall 2015

21

RESEARCH

XI RECEIVES NIH GRANT TO

Study Colorectal Cancer r ag ang i a scientist at USA Mitchell Cancer Institute, has recently been awarded an RO1 research grant of o er fi e years from the National Cancer Institute at the National Institutes of Health.

Dr. Xi will study the mechanistic role of small non coding molecules (i.e. miRNA) in chemoprevention of colorectal cancer.

revious stu ies b r i demonstrate that low dose sulindac, a generic NSAID, can dramatically restrict the spread of human colon cancer cells b a novel non C in ibitor mechanism that appears to involve the suppression of a panel of oncogenic miRNAs. MicroRNA has emerged as a new class o small mole ules it broa clinical potential as diagnostic biomar ers an t era euti targets for various human diseases.

Numerous studies have demonstrated that nonsteroidal anti in ammator ru s (NSAIDs) such as aspirin, are able to si ni antl in ibit t e progression of different tumor cells. The downside of NSAIDs is t eir in ibitor e e t on C enzymes that are present in the uman bo otential eart an kidney toxicities resulting from C in ibition re lu e t e lon term use of NSAIDs for cancer chemoprevention.

Dr. Xi’s recent results show that a tumor suppressor miRNA, mi an be in u e in human colorectal cancer cells in response to sulindac treatment Mi as been known for its suppressive role in the growth and spread of tumor cells. In this funded project, Dr. Xi will lead his team to study t e me anism b i mi 200 mediates the anticancer activity of sulindac and its non C in ibitor erivatives in different colorectal cancer models. The expected results will advance the understanding of low toxic anticancer properties of NSAIDs in human tumors, and support the development of safer and more effective drugs for preventing colon cancer.

Fortunately, the latest studies show that NSAIDs can act through COX-independent mechanisms, eliminating the ear o atal to i it better understanding of the COXindependent anticancer properties of NSAIDs can provide new insight into the development of safer drugs against cancer.

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Minds Conquering Cancer | Fall 2015

Prior to his Ph.D. training, Dr. Xi was a practicing surgeon.

In r i establis e is independent research programs after completing his postdoctoral training at MCI and is currently an associate professor of on olo i s ien es in t e basi and translational research department at MCI. He has aut ore over ubli ations in peer-reviewed journals and has been onore it numerous prestigious awards. Including this recent grant, Dr. Xi has secured a total of $3.2 million in research funding from the American Association for Cancer Research, American Cancer Society, and National Institutes of Health to support his research on preventing the spread of human cancer.

PIAZZA GRANT TO DEVELOP

New Colon Cancer Drugs Dr. Gary Piazza, chief of the r g isco ery Research Center and professor of oncologic sciences at USA Mitchell Cancer Institute, has been awarded an RO1 research grant in the amo nt of from the National Cancer Institute at the National Institutes of Health to continue his work toward de eloping new dr gs for the treatment or prevention of colon cancer.

The long term use of nonsteroidal anti in ammator ru s I s including aspirin, are known to ave reventive bene ts for reducing the incidence and risk of death from colon cancer as well as other forms of cancer. Prescription strength NSAIDs such as sulindac can also shrink precancerous poylps in individuals at high risk of developing colon cancer and may have therapeutic activity for colon cancer patients.

However, the long-term use of such drugs is not recommended be ause o otentiall atal si e effects associated with COX in ibition an t e su ression of physiologically important mediators referred to as prostaglandins.

Dr. Piazza and other investigators throughout the world have

ot esi e t at t e basis or the anticancer activity of NSAIDs ma not re uire C in ibition but involves sele tive illin o tumor ells b a s e iali e cellular process known as a o tosis r ia a believes that safer and more effective ru s an be esi ne b chemically modifying sulindac to blo its C in ibitor a tivit while targeting the underlying mole ular at a res onsible or its abilit to sele tivel in u e apoptosis of cancer cells.

Dr. Piazza’s group at MCI has extensively studied the me anism b i sulin a induces apoptosis and has ublis e numerous s ienti papers reporting that its anticancer activity is closely asso iate it its abilit to in ibit another enzyme called cyclic guanosine monophosphate phosphodiesterase (cGMP PDE).

Dr. Piazza’s team, which includes 10 other scientists, has recently is overe t at a s e i M PDE enzyme, PDE10A, is elevated in colon tumors and essential for tumor ell ro t but not or t e growth of normal cells.

The team has synthesized a series o non C in ibitor derivatives of sulindac that otentl an sele tivel in ibit PDE10A and tumor cell growth. u om oun s are bein developed at MCI, while studies

to better e ne t e role o in an er ill be a ma or t rust o the new grant award.

In this research project, Dr. Piazza and his team will design and synthesize novel sulindac derivatives with yet higher oten an sele tivit to in ibit PDE10A and will determine the activity of promising sulindac derivatives in preclinical models of colon cancer and metastasis. tu ies ill also be on u te to further explore the role of PDE10A in colon cancer.

Dr. Piazza hopes to identify a safe and effective experimental compound that will merit human testin in lini al trials stablis in a role of PDE10 in colon cancer may also provide insight to new biomar ers an ima in met o s for the early detection of colon cancer. n bra am Mit ell Distinguished Investigator, Dr. Piazza is a professor of oncologic sciences and pharmacology at t e niversit o out labama An inventor on more than 50 patent applications and 100 s ienti ubli ations r ia a is also a co-founder of ADT arma euti als In a Mobile area base arma euti al company that is developing new anti-cancer drugs that target PDE10 as well as the Ras oncogene.

Minds Conquering Cancer | Fall 2015

23

New Director Dr. Michael Finan will provide strategic direction an oversee bot lini al an research initiatives at MCI.

F N A N I F e th

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Minds Conquering Cancer | Fall 2015

NEW DIRECTOR SPEARHEADS AN AMBITIOUS FIVE-YEAR PLAN

E R U T U F When Dr. Michael Finan came to Mitchell Cancer Institute 10 years ago he immediately recognized its potential

A New Orleans native, Finan was residency program director for the Ochsner Department of Obstetrics and Gynecology in his hometown when he was recruited to MCI in 2005 to fill a newly vacated, sole position in gynecologic oncology. At that time, the MCI facility was in the blueprint stage, but shortly after he arrived construction began on a site near Children’s & Women’s Hospital.

“One of the biggest reasons I came to MCI was the opportunity to be a part of developing a world-class division of gynecologic oncology in a world-class facility from scratch,” said Finan.

MCI represented the largest single research endeavor in the history of the University of South Alabama, with

a total investment of well over $135 million, including $85 million in construction and equipment.

Finan worked his way up, serving as associate director for clinical affairs and interim director before being tapped for the top position in May. At the same time, he saw patients in his practice, earning recognition from U.S. News & World Report as one of the top gynecologic oncologists in the United States.

Since 2005, MCI has grown to be the area’s leading cancer institution, with nearly 300 employees and an annual impact of $217 million on the regional economy.

In 2014, more than 2,900 new patients were treated at MCI, generating more than 50,000 patient visits.

As director, Finan will provide strategic direction to MCI and oversee both clinical and research initiatives, including management of the complex clinical operations. In addition, he will work closely with the MCI leadership team to nurture the growth of the research programs, while providing state-of-the-art care for cancer patients.

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DESIGNATED CANCER CENTER The goal of MCI’s founders – including the late University of South Alabama President Gordon Moulton, first MCI Director Dr. Mike Boyd and the Mitchell family – was to build a National Cancer Institute (NCI) Designated Comprehensive Cancer Center. These 68 centers across the United States form the backbone of the NCI programs for studying and controlling cancer.

A key component of Finan’s five-year strategic plan for MCI is achieving that goal through a consortium partnership with the University of Alabama at Birmingham (UAB). In order to serve as a viable partner, MCI must increase its level of total research funding from $5 million to $10 million a year by 2020. This goal is certainly achievable, given that MCI received nearly $5 million in grant funding in the first six months of 2015. MCI also is recruiting additional physician-scientists to grow its clinical programs.

MCI’s robust clinical trials program made it an appealing partner to UAB. Clinical trials, where new cancer treatments are tested, have been a major contributor to the significant strides that have been made in survival rates and quality of life for patients.

MCI had over 400 patients enrolled in 2014, 39 percent of them minorities, a population usually underrepresented in trials.

By earning the designation, MCI would join an

“One of the most unique aspects of MCI is access to these trials,” said Finan. “There are nearly 40 clinical trials open at any one time, a deep and broad palette that encompasses a variety of cancers.”

PHYSICIAN ROLE INFORMS NEW POSITION

to develop an early detection screening test. Dr. Finan is a co-inventor on six patent filings related to this technology.

Despite being named one of the top gynecologic oncologists in the United States, Finan’s role has shifted away from being a practicing gynecologic oncologist.

Still, he feels his background as a physician grounds him.

Research is at the heart of what MCI does, and this conforms to the primary goal of an NCI Designated Cancer Center: to conduct research leading to reductions in cancer incidences and mortality rates.

Approximately 50 percent of the square footage of the MCI facility is devoted to basic and translational cancer research.

“On many tough days, it has been the patients and their families who have kept me motivated and who have inspired me,” he said. “I feel that my background as a surgeon allows me to be decisive when tough decisions need to be made, yet I am hopeful that my 23 years as a clinician will keep me grounded and allow me to find solutions, keeping the interests of patients and their caregivers a priority.”

In his practice, Finan treated many patients battling ovarian cancer, one of the deadliest forms of the disease.

This experience led to promising research and a partnership with Dr. Rodney Rocconi and Dr. Lewis Pannell on technology licensed by Swift Biotechnology

26

exclusive club of comprehensive cancer centers, which includes M.D. Anderson, Memorial Sloan Kettering and Johns Hopkins. For residents in MCI’s referral zone, which encompasses 4.1 million people in a 150-mile radius, that designation means patients can receive leading-edge cancer care close to home. Being a consortium partner will also allow MCI additional resources, as well as access to further funding and advanced clinical trials.

Minds Conquering Cancer | Fall 2015

The basic research programs at MCI include DNA Damage and Repair led by Dr. Robert W. Sobol and Drug Discovery and Cancer Prevention under Dr. Gary Piazza. MCI is currently recruiting for the third program, Cancer Biology, which focuses on cancer biomarkers and cancer cell metabolism and death.

To date, intellectual property emerging from MCI has resulted in the filing of more than 45 patent applications as well as the startup of at least five companies: Swift Biotechnology, Creatics, ADT Pharmaceuticals, PDEi Pharmaceuticals and Tatva Biosciences.

“I look forward to taking MCI to the next level in all areas of patient care, education, clinical research and translational resear

FROM LSU TO THE FBI Finan and his wife of 29 years, Melinda, have twins who are 18-year-old seniors at St. Paul’s Episcopal School in Mobile. Daughter Tatiana is on the St. Paul’s swim team. Noah is an outdoorsman who enjoys hunting, a passion Finan shares. An avid LSU football fan, Finan enjoys traveling to see the games.

One of Finan’s more unusual side jobs is that of a volunteer police surgeon for the Mobile Police Department. This requires being on call during certain activities like Mardi Gras parades, when police officers are in potentially high-risk situations. He is also a member of the FBI Citizens Academy, designed to build relationships between professionals in the community and the FBI.

Finan received his undergraduate degree from the University of New Orleans and his medical degree from the LSU Medical Center School of Medicine in Shreveport. He completed both his residency in obstetrics and gynecology and a fellowship in gynecologic oncology at the University of South Florida at Tampa General Hospital and the H. Lee Moffitt Cancer Center in Tampa.

“I look forward to taking MCI to the next level in all areas of patient care, education, clinical research and translational research,” he said. “We have great people here, and I am honored to have been chosen to lead them as director. The future is bright for us on every front.”

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27

TREATMENT

28

Minds Conquering Cancer | Fall 2015

TAN

GRIMM

TAYLOR

RIDER

MCI’S TEAM APPROACH GI CANCER DOCTORS PART OF

For the scientists, physicians and other health professionals at Mitchell Cancer Institute, all cancers are cause for concern.

Yet they also know that some forms of cancer may be tougher than others, as in the case of certain kinds of gastrointestinal (GI) cancers.

Gastrointestinal cancer includes cancers of the esophagus, gallbladder, liver, pancreas, stomach, small intestine, colon and rectum. Some form of gastrointestinal cancer is newly diagnosed in more than 250,000 patients annually in the United States — about 20 percent of all newly diagnosed cancers every year. Pancreatic cancer continues to have a very high mortality rate. Colorectal cancer is one of the leading causes of cancer-related deaths in the United States, even though early detection can often lead to a complete cure.

MCI is committed to fighting — and winning — the battle against all cancer, including many of the toughest forms of GI cancer. As the only academic cancer treatment institute in the Gulf Coast area, MCI is able to provide an exceptional depth of knowledge and access to leading-edge research and technology along with a caring and compassionate approach to patient care. Working as a multidisciplinary team in a highly collaborative environment, MCI brings many expert minds together — primary physicians, researchers, oncologists and others — to conquer cancer.

Among the many minds at MCI engaged in the fight against GI cancer are Dr. Marcus Tan, gastrointestinal/oncologic surgeon; Dr. Lee Grimm Jr., colorectal surgeon; Dr. William R. Taylor, medical oncologist; and Dr. Paul F. Rider, colorectal surgeon.

This team approach is at the core of MCI’s commitment to conquering cancer, and it is showing significant results. For the cancer treatment professionals at MCI, that is the most important test of any breakthrough — the amount of hope it will raise and the number of lives it will save.

For more information on the GI group at MCI contact Susan Crut el Mana er o si ian an Communit utrea at or s rut el ealt sout alabama e u

Successful

LAY NAVIGATION PROGRAM EXTENDED For almost two years, MCI patients ave bene te rom t e servi es of four lay navigators to help guide them through the complexities of a cancer diagnosis and treatment.

The program assists Medicare atients over ia nose it cancer. Each patient is assigned a lay navigator who helps them and their caregivers decipher information, and assists them as needed through their treatment program. They act as roblem solvers el in remove barriers to are an mat in patients with appropriate resources. in e t e ro ram be an over atients ave received services, according to Cathy Tinnea, nurse navigator and site manager for the grant.

“A cancer diagnosis is just so over elmin sai Tinnea ere a navi ator reall el s is in brea in it o n into mana eable etails an anti i atin nee s be ore t e atient even no s t e ave t em The lay navigator program is part of the Centers for Medicare & Medicaid Services grant with consortium partner University o labama at irmin am Comprehensive Cancer Center.

The goal of the program is to prove t at atients et a better ualit of care at a lower cost with the guidance of a navigator.

The program was scheduled to run t rou une but it as been recently extended through January

Minds Conquering Cancer | Fall 2015

29

TREATMENT

Nurse

GAINS NEW Perspecti v e INSPIRES OTHERS As A PATIENT

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Minds Conquering Cancer | Fall 2015

S

usan Hofelich is wearing a candy-colored, bright pink wig. It’s Dec. 5, one day after the 47-year-old completed her cancer treatment at Mitchell Cancer Institute.

increases the dose intensity with shorter intervals between the cycles.

While it has proved to be successful in treating breast cancer, the regimen can be more debilitating for the patient.

The wig was a gift, given as part of a celebration thrown by her colleagues and spearheaded by her nurse, RN Stephanie Lett.

In addition to being a patient, Hofelich is also a clinical nurse in the MCI infusion suite.

Throughout the ordeal, Hofelich kept working, treating patients in the infusion suite and only missing one day. She was a cheerful presence, holding her patients’ hands, always quick with an encouraging word or doing “stupid things” to make them laugh.

really understand what a patient endured until she went through it with her friend, day after day.

“I was surprised by the fatigue,” said Lett. “You could see Susan struggle to take a step.”

Hofelich gained new respect for patients as well. “These patients have got to be commended for their strength,” she said. “The fatigue was beyond words. ‘Chemo brain’ is not an illusion, that’s real.

And the swelling was bad.”

“I tell my patients I’ve done my walk and I’ll help you get through ours

o eli

sai

I o

understand where you’re coming rom

n it s oin to be

A glance at her nametag shows a photo of a woman with long blonde hair.

“I did have pretty hair,” she said wistfully.

As a patient, life was a little different. Hospitalized twice for a bad infection from her port and for an episode of respiratory failure, she admits to some difficult times.

Hofelich was diagnosed with stage III cancer in her left breast in May 2014. As an oncology nurse, she knew a lot about the treatment of the disease. But being on the receiving end offered a different perspective.

“It’s true what they say. Nurses also make terrible patients,” she remarked. “But I had a great support group, and not everybody has that luxury. If it weren’t for my husband and Stephanie, I wouldn’t have made it. I went through some dark places. She was my strength.”

A patient of oncologist Dr. Daniel Cameron, Hofelich was prescribed a course of treatment that included Taxol for 12 weeks and Adriamycin Cytoxan on a dose-dense basis.

Dose-dense chemotherapy

Lett downplays her role, but acknowledges that even for a veteran nurse, assisting Hofelich with her treatment was an eyeopening experience. An oncology nurse since 1986, she says she didn’t

As the end of treatment approached, Lett secretly planned a celebration, ordering 30 pink scarves for the staff to wear as a show of solidarity. The pink wig, which came from a store in Memphis, was the final touch.

While the outpouring of support was a surprise to Hofelich, Lett felt it was well-deserved.

“You get back what you give,” said Lett. “Patients see Susan as such a strong person. She’s bubbly. She inspires them.”

“I tell my patients I’ve done my walk and I’ll help you get through yours,” Hofelich said. “I do understand where you’re coming from. And it’s going to be OK.”

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ROSE GARDEN PROVIDES

Beautiful B

SETTING FOR PATIENTS ernard “Berney” Malkove has always loved roses. Perhaps it is because his mother’s name was Rose, and that early on she instilled a fondness for the flower in her son.

That early interest grew into an avid hobby later in his adulthood. For over 25 years, Malkove, a commercial real estate developer, has been growing roses, adding more until his yard was dotted with 125 hybrid tea rose bushes.

In January, Malkove donated the bushes to Mitchell Cancer Institute to create a rose garden on the south side of the building. He designed the garden and oversaw the transplanting of the trees. Working alongside the MCI grounds crew, he shared a lifetime of advice on roses and all took great pride in the project’s outcome.

“When you have things of beauty, you like to share them,” Malkove explained. “My hope for this garden is that for patients and families it becomes a place of life and beauty, and a serene spot to meditate.”

Malkove knows about the emotional strain of dealing with cancer. Diagnosed with Hodgkin’s disease 60 years ago, the 85-year-old was familiar with MCI through his annual visits to oncologist Dr. Thomas Butler.

He disputes the common perception that roses are difficult to grow. While he claims they’re not hard to care for, they do require regular spraying and feeding, the right soil and six hours of sun.

“Roses are like chickens that lay eggs,” he said. “If you keep feeding them, they’ll keep producing.”

His rose bushes bloom continually, and will offer a welcome splash of color to visitors throughout the year. Already the garden has fulfilled Malkove’s purpose, bringing peace to many of MCI’s patients, some of whom visit the garden weekly before entering the building for treatment.

I

32

ou are intereste in volunteerin in t e ar en

Minds Conquering Cancer | Fall 2015

onta t

re

olin at

Minds Conquering Cancer | Fall 2015

33

OUTREACH

Love andComfort Sew & Sow Ministry Spreads

Members of Sew & Sow at the 2014 Think Pink Tea: (l to r) Leaster Koen Dumas, JoAnn Brown, Kate Anderson, Lucille Adams, Minnie Havard, Sylvia Brown, Loretta Loper, Frances Brown, Louise Whigham (not pictured: ean eal ouise o man obbie Connell ean ritton elen rimes illie Mae ro n an a e em

T e members o Millr a tist Church’s Sew & Sow ministry are on a mission to increase the comfort of patients at Mitchell Cancer Institute.

Through their ministry, they have donated several hundred port covers and pillows, according to Sylvia Brown, the 85-year-old leader of the group and former Millry postmaster for 34 years.

For many members of the sewing circle, the MCI ministry is personal. Three-time cancer survivor Lucille Adams said, “For me, it helps me to give back.”

Loretta Loper joined Sew & Sow when she was diagnosed with cancer. At 64, she is the baby of the bunch.

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Minds Conquering Cancer | Fall 2015

MCI is not the only recipient of the group’s largesse.

Sew & Sow has donated dresses to Haiti and Guatemala through mission trips. Blankets have been distributed to shut-ins and local nursing homes. In Mobile, members have created blankets and other items for patients at USA Children’s & Women’s Hospital and other local hospitals.

When disaster strikes, the women start sewing. The group provided more than 200 dresses and blankets to victims of the Tuscaloosa tornado in 2011.

“We feel it’s a ministry of the Lord to help, but we have a good time, too. And we’re going to keep doing it as long as we can,” Brown vowed.

To cover the cost of materials, the Sew & Sow group relies on member ontributions ar sales an abri onations I ou are interested in donating materials or funds, send them to Sylvia ro n o Millr a tist C ur o Millr

MCI RECEIVES GRANT FOR

CRC Outreach Mitchell Cancer Institute received an $89,000 grant from the Alabama Department of Public Health to focus on work site wellness for colorectal cancer (CRC) screening and pilot an automated telephone system in University of South Alabama primary physician practices for CRC screening reminders.

MCI has already established community, work site and physician partners, and was wellpositioned to develop these programs. In addition, MCI has a longstanding relationship with ADPH on various aspects of colorectal cancer education including two statewide CRC surveys in 2010 and 2014 of primary care physicians.

Since January, work site wellness programs were implemented at the University of South Alabama, Evonik, Norton Lilly International and Austal USA. Working with human resources and wellness staff, MCI provided Lunch and Learn sessions to promote education, awareness and CRC screenings to all employees 50 years and older through the use of a take-home stool test called a FIT (Fecal Immunochemical Test). Various incentives were provided throughout the campaign to help encourage compliance, including a drawing to win a $500 Best Buy card for USA participants.

The automated patient phone call reminder system was piloted in USA primary care practices, including USA Family Medicine, USA Physicians Group, Stanton Road Clinic and USA Mastin Clinic. Medical oversight was provided by Dr. Allen Perkins, chair of USA Family Medicine. The system identified patients age 50 to 75 and encouraged those who were out of compliance with recommended CRC screening guidelines to receive a take-home FIT in the mail or schedule a colonoscopy through USA Digestive Health Center. A community health worker followed up on the automated calls to provide education about the FIT, reminded patients to return the tests, answered questions and assisted in scheduling colonoscopy appointments.

At the completion of the pilot program, an extensive report of both initiatives will be provided to ADPH. A primary goal of the worksite initiative and automated phone reminder system is to develop programs that can be scaled up and rolled out on a larger statewide basis, with the goal of increasing screenings and detecting colorectal cancer in its earliest stages, when most treatable.

Minds Conquering Cancer | Fall 2015

35

OUTREACH

ALABAMA’S PREVENTABLE HEALTH MENACE

COLORECTAL CANCER (CRC) STAGE 5 STAGE 4

2ND LEADING CANCER

KILLER

STAGE 3 STAGE 2 STAGE 1

42.9%

of CRC diagnoses were 4 made at Stage 3 or Stage 4.

Black Alabamians are 20% more likely to suffer from CRC than white Alabamians.

CAUSED

...despite effective screening methods that can catch CRC in its earliest stages or prevent it.

980 DEATHS IN ALABAMA

IN 2012

ALABAMA FITWAY PROGRAM Aims to increase screening rates 2013 to 80% by 2018 from 68.3% in 2013.

How can we get there Information provided by University of South Alabama Mitchell Cancer Institute, Alabama Department of Public Health, American Cancer Society and the FITWAY Alabama Program.

Wider adoption of take-home stool tests like the FIT (Fecal Immunochemical Test) Less reliance on colonoscopy, except for those with known risk factors Better physician reminder systems through use of Electronic Health Records Fewer procrastinating patients due to more screening options

Mit ell Can er Institute teame u it t e labama e artment o ubli ealt in to on u t a survey of primary care physicians regarding CRC s reenin ra ti es no le e an be aviors an ma e re ommen ations base on t e ata as art o t e IT labama Colore tal Can er revention ro ram un e b a rant rom t e Centers or Disease Control, FITWAY aims to increase screening rates in labama amon t ose an ol er to er ent b

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Minds Conquering Cancer | Fall 2015

MCI GOES BLUE MCI partnered with the American Cancer Society on its 2nd Annual “Let’s Go Blue” campaign and its program “Shop Talk” in March and April. The program recruits area barber shops and hair salons to put out colorectal cancer information, as well as talk with their customers about the different forms of screening available.

This year’s program was hosted by Optimum Cuts & Styles. The owners decorated their shop in blue and wore colorectal cancer awareness T-shirts to spread education and awareness of the importance of colorectal screening to customers. Other participating shops included J. Maurice the Salon, Vincent’s Headquarters, Headquarters Barber & Style Shop, Split Enz Styling Team, 3 Barbers, Custom Cuts Barbershop, Lucy’s Barbershop, Studio 17 and Five Star Barbershop.

Minds Conquering Cancer | Fall 2015

37

OUTREACH

F F B

Bringing Together Breast Cancer Survivors

The acronym BFF commonly refers to Best Friends Forever. But for people in t e Mobile area

an also stan

for Breast Friends Forever, a support rou

or breast an er survivors

On the first Tuesday of each month, the multipurpose room at Mitchell Cancer Institute serves as a meeting space for BFF. The meetings begin at 5:30 p.m., and during their time together, breast cancer survivors find themselves in a safe space to talk with other survivors

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Minds Conquering Cancer | Fall 2015

about their experiences with battling the disease.

The group provides support, as well as educational opportunities like cooking classes, physical exercises geared toward survivors, and crafting projects.

According to Darlene Chavers, a breast cancer survivor and founder of the group, “Being a breast cancer survivor is like being in a sorority. My breast cancer journey had led me places I never thought I would go.

It has given me a boldness I never knew I had, and I have met people I would have never met otherwise. No matter where you are in this journey, we would love to have you join us.�

ncology

Outlook 2015 highlight of the conference was t e C oosin

isel

anel is ussion

ore than attendees enjoyed awless weather in the perfect setting at the ncology tloo conference at the rand otel arriott esort in Point Clear March 20-21.

Dr. Thomas Butler and Dr. Mary Vu served as co-coordinators for this year’s program, which featured a selection of distinguished speakers from the el o on olo T e o us o t e on eren e as relate to t e stu and treatment of many types of cancers, including myeloid leukemia, multiple myeloma, Hodgkin’s Disease, and non-Hodgkin’s Lymphoma.

Conference attendees were comprised of primary care physicians, oncologists, hematologists and other medical professionals.

T e bi bene t o n olo utloo is t at it eatures national level s ea ers it t e most u to ate in ormation on an er sa s r utler “Another advantage is our setting and size, which allows for more audience participation and one-on-one interaction that can lead to uture ollaboration BFF presenter: an rum el dietitian for Mitchell Cancer Institute, shared healthy summer recipes at the April meeting.

In addition to Chavers, BFF is supported by board members which include: Dr. Lynn Dyess, Wilma Baliem, Cathy Tinnea, RN, Jeanie Mann, Julia Raleigh, Joanie Broemelsiek, RN, Shirley Wright and Beryl Adkisson, RN.

For more information, contact Darlene Chavers at or email her at avers bellsout net or n t e rou t rou its a eboo a e BFF-Breast Friends Forever.

A highlight of the conference was the invigorating and thought-provoking “Choosing isel anel is ussion T e ro ram is art o a campaign to help health care providers and patients engage in conversations to reduce overuse of tests and procedures, particularly toward the end of a patient’s life.

Dr. Thomas Butler served as co-coordinator of the event with Dr. Mary Vu.

T e s ea ers or n olo utloo in lu e arr rba M rom niversit o labama irmin am o n reer M rom an erbilt niversit a uel Innis elton M rom u iano Costa M rom Morton Coleman M lini al ro essor o me i ine at Cornell niversit s eill Me i al Colle e avi Clar son M rom t e Mit ell Can er Institute T omas Tu er M rom t e niversit o entu s Colle e o ubli ealt an C arlie nu M rom t e Brody School of Medicine at Eastern Carolina University.

Oncology Outlook, a continuing medical education conference, is s onsore b Mit ell Can er Institute an t e niversit o out labama Colle e o Me i ine T e on eren e ill be el on Mar 18-19 and will cover issues related to supportive oncology.

Minds Conquering Cancer | Fall 2015

39

OUTREACH

HUNDREDS CELEBRATE

Cancer Survivors Day Over 200 cancer survivors and supporters gathered at the labama Cr ise erminal on June 7 to celebrate National Cancer Survivors Day. The event, sponsored by Mitchell Cancer Institute, featured inspirational speaker and performer Rhett Butler. utler e es eas lassi ation are iver or man ears or is terminall ill brot er e is an internationally renowned virtuoso guitarist well-known for playing two guitars at once, an author and documentary director. He is also a ormer niversit o out labama stu ent and is pursuing a medical degree at 38. ntertainment in lu Tears rom eaven ma in ra e ro to o more

e t e musi al numbers on t e u ulele an utler also en oura e t e to t an er

In keeping with that sentiment, the program recognized MCI cancer survivors who are ivin ba or arlene C avers a brus it cancer turned into a mission to form Breast rien s orever a breast an er su ort group. Lisa Freeman’s cancer experience led to serving as 2013 GO Run chair and on the Patient Advocacy Council. Survivor Annie Winston participates in clinical trials at MCI. While acknowledging the advances that have been ma e in an er treatment an revention Mitchell Cancer Institute Director Dr. Michael inan a mitte t e battle is ar rom over T ere s been no lunar lan in so to s ea T ere s been no mira le ure but e are making incremental improvements, and patients are avin more an more o e e sai The event was held as part of National Cancer urvivors a i is observe in un re s o communities nationwide and around the world.

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Minds Conquering Cancer | Fall 2015

DEVELOPMENT

COL OR FUL PATIENT PAYS POSTHUMOUS TR IB UTE TO

Her Favorite

Doctor The plaque outside the caregiver station named in Dr. Taylor’s honor.

Donor Profile By all accounts, Cindy Manderson was a colorful woman. Fond of costumes and convertibles, she would often show up dressed for appointments with MCI oncologist Dr. Bill Taylor in an outfit befitting the season.

“Cindy could brighten up a room,” said Taylor. “She was one of those patients you look forward to seeing. And you always knew when she was here. She was boisterous.”

Taylor met Manderson under the worst of circumstances. She had received a diagnosis of adenocarcinoma, stage IV metastatic lung cancer.

It was a grim prognosis and a difficult course of treatment, even for someone with an irrepressible spirit.

Fortunately, her older sister Teri was there to support her along the way.

“Once Cindy got on board with her treatment, she faced it with a sense of mission, courage and bravery. She was a tiger at that, just like everything else,” said Taylor.

A die-hard Alabama fan, she loved having Taylor, an Auburn grad, for an oncologist and the rivalry became a source of constant ribbing. Over the course of three years of treatment, she became one of Taylor’s favorite patients in his 32 years of practice.

Born and raised in Tuscaloosa, Manderson was a graduate of the University of Florida. She lived in Houston, Tuscaloosa and Birmingham before moving to Fairhope in 2003. She worked at Marriott’s Grand Hotel

and Three Georges candy store. She performed in plays at Theatre 98 and volunteered in community activities. She was an avid pet lover who treated her dogs like children.

“Cindy had a way of making people enjoy living even in the gloomiest situations. She had a real gift for making people happy.”

Just three months after her sister Teri passed away, Cindy Manderson died of lung cancer on June 19, 2013, at age 61.

That could have been the end of the story, except it turned out Dr. Taylor had also been one of Manderson’s favorites. She was so appreciative of his care that she left an estate gift that was used to create a room in the medical oncology suite in his honor. When Taylor found out, he was shocked.

“I couldn’t believe it,” he said. “I was truly overwhelmed and touched that she would do something like that for me. I never imagined someone would honor me in this way.”

When he thinks of Manderson’s legacy, he smiles.“Cindy had a way of making people enjoy living even in the gloomiest situations. She had a real gift for making people happy.”

Minds Conquering Cancer | Fall 2015

41

DEVELOPMENT

Dennis Harris of Zimlich the Florist created beautiful floral designs. Guests were entertained

by Sharon Carroll and Company’s soulful jazz repertoire.

The sixth annual Celebrate Hope on Nov. 20, 2014, was the most successful event to date, raising more than $388,000 in net revenue, and topping the 2013 event, which netted over $380,000.

Celebrate Hope offers a chance to contribute locally to advances in cancer research while also enjoying an evening of delicious food, fine wines, craft beers and live entertainment. The event was chaired by Catherine and Michael Druhan and the presenting sponsor was The Mapp Family Foundation.

Guests dined on signature dishes that were created by Aramark, Bay Gourmet Catering, Camellia Cafe, Delish’s Desserts and Eatery, Fisher’s at Orange Beach Marina, Half Shell Oyster House, J.A.M. Cakery, Legacy Bar & Grill, Ruth’s Chris Steak House, The Trellis Room, Wind Creek Casino and Hotel Atmore, The Bull, The Fairhope Inn and Georgia Roussos Catering.

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Minds Conquering Cancer | Fall 2015

“So many of our young friends have been touched by cancer, so Celebrate Hope is important to us,” said Catherine Druhan.

Once again, the Beau Rivage Resort and Casino sponsored the Premier Partner Package for sponsors in January that featured an upscale cocktail party and tickets to attend a Rick Springfield concert.

This year’s funds will go toward MCI’s early detection cancer research program. Scientific teams working at MCI in the lab of Dr. Lewis Pannell have established a non-invasive approach to collect fluids for the detection of highly specific protein biomarkers that could eventually become a clinical screening test for these aggressive, and otherwise deadly diseases.

Altogether, Celebrate Hope has raised more than $1.8 million over the history of the event.

T e sevent annual Celebrate o e resente b in Cree Casino and Hotel Atmore, is scheduled for Thursday, Nov. 19.

For sponsorship information and complete details visit usam i om elebrate o e

Life Program works with hospitalized children, teens and their families to ensure that a child’s developmental, educational and emotional nee s are met T e ro ram as un e b a $500,000 grant from the foundation.

T is is t e rst ear t e oun ation as s onsore Celebrate o e t ou an er is an issue that is close to the Mapps’ hearts.

ouis an Melin a Ma ave uietl built a legacy of helping others along the Gulf Coast through their Mapp Family Foundation.

T eir lar esse is not limite to one area but supports projects in the arts, animal welfare and health care.

One example is USA Children’s & Women’s Hospital, where the Mapp Child and Family

Celebrate

Hope 2014

sponsors

Presenting Sponsor -

Cellar Master

- Beau Rivage Resort and Casino bra am Mit ell - Arlene Mitchell - Press-Register - USA Foundation - Wind Creek Casino and Hotel Atmore

Chef de Cave

- Agency VERGE ul istributin Com an o Mobile e us o Mobile Mobile as em ra Com an Mobile ire ters sso iation - Mr. and Mrs. Russell R. Steiner

Wine Maker

- Beard Equipment Company Inc. lo is onneborn Trust

Enophile

- Anonymous - Duvalle Family Trust - Florence Foundation - Jo Ann and Cortez Fowler Family u re an Ma ol ber arbara an ernar Mal ove

C

“As a cancer survivor, I know the feeling when you are told you have cancer. It can be real s ar ouis Ma sai T e iti ens o our area are so blesse to ave t e Mitchell Cancer Institute that gives hope to so man an or t at e are ver t an ul Taking inspiration from the passage from Luke rom ever one o as been iven mu mu ill be eman e an rom t e one o as been entruste it mu mu more ill be as e T e Ma amil Foundation seeks to improve the quality of life of those it is privileged to support.

- Laura and Ben Meisler - PNC Bank - Ruland & Ruland CPAs LLC - Wells Fargo

Grand Sommelier

labama Cro n - Aramark-USA Dining Services - Bay Shore Finance Inc. - Blue Rents, Inc. - Lisa and Barry Bukstein - CIMCO Refrigeration Inc. - Cox Nuclear Pharmacy LLC - C-Spire - E.E. Delaney Foundation Inc. - Mr. and Mrs. J. Michael Druhan III In rmar ealt stem - Laureen H. Lynn Mobile ir ort ut orit - Ashley and Wesley Naile - P&G Machine & Supply Co. Inc. - Page & Jones Inc./Michael Lee - Pinnacle Imports - Smith, Dukes & Buckalew LLP - Melanie and Bill Susman - Zimlich the Florist Inc. /Dennis C. Harris, AIFD, CAFA

Connoisseur

- AltaPointe Health Systems Inc. - Susan and Miles Ball - Bay Paper Company/Alan Hirsch - BBVA Compass - Mr. and Mrs. Mack B. Binion - Mr. and Mrs. Donald M. Briskman - Dr. and Mrs. Fred Bodie - Yaffa and Mark Brown - Lydia Ladd Chandler - Colonial Trailways

- Community Bank r arbara an Tom Cor oran - Cox Family Foundation - Dr. and Mrs. Michael A. Finan and family - Firetrol Protection Systems - Dr. Steve and Lisa Furr - Sandra and Harvey Gandler - Genentech - GoDaddy.com Bowl - Tricia and Duane Graham - Joy and Jimmy Grodnick - Hoar Program Management - Holiday Inc. - International Shipholding Corporation - Stella and Charlie Jackson - Helen and Neil Kennedy - Mr. and Mrs. James M. Ladd - Live Oak Landscaping - Allison and Frank Lott Mr an Mrs erbert Meisler - Lori and Ken Metzger - Councilwoman Bess Rich and Dr. Leonard Rich - Royal Cup Coffee - Lynnie and Danny Sheridan - Tonia and Jerry Silverstein - Scott Silverstein Mr an Mrs Coo er T urber - Trustmark National Bank - USA National Alumni Association - Mr. and Mrs. P. Dean Waite - Gail Walker and Harold Buchman - United-Johnson Brothers Mr an Mrs C i er alters eri an a eber - Douglas Whitmore - Wilkins Miller Hieronymus LLC - Margaret Ramsey Wright

Minds Conquering Cancer | Fall Fall2015 2015

43

DEVELOPMENT Breast Cancer Survivors and Loved nes Celebrate at the Think Pink Tea. USA Mitchell Cancer Institute and Children’s & Women’s Hospital joined together on Oct. 2, 2014, to host the 5th annual Think Pink Tea at Geri Moulton Children’s Park.

Presented by the Vincent F. Kilborn Charitable Foundation, this fundraising event has become a popular tradition, outgrowing its previous location in the MCI lobby. The event celebrates Breast Cancer Awareness Month, and honors impacted friends and family of both breast cancer survivors and those still fighting cancer.

2014

In addition to performances by Mr. Kilborn, as well as the USA Prowlers Dance Team, the Think Pink Tea featured a fashion show hosted by Hertha Green, owner of Hertha’s Consignment

and sponsored by Dillard’s of Mobile and W Hair Salon. The event was catered by Martha Rutledge Catering.

The fashion show catwalk was lined with cancer survivors, supporters and MCI nurses, as well as several doctors showing off fashions for the event. Among these stylish M.D.s were Dr. Carol Wiseman Norden and Dr. Jennifer Scalici, who was joined by her daughter, Genevieve.

MCI Patient Navigator Nwamaka Ikefuna and Dr. Julee Waldrop, the wife of University of South Alabama President Tony Waldrop, also modeled fashions for the event. Many familiar MCI and Children’s & Women’s faces lent an arm to escort the fashion show models. These escorts included Dr. Louis Pannell, Dr. John Russell, Dr. Michael Finan, Owen Bailey, and Kilborn.

The Think Pink Tea was the launch event for the Vincent F. Kilborn Charitable Foundation, which is dedicated to healing, as well as researching a cure for breast and other cancers.

T e in ent ilborn C aritable oun ation is the presenting sponsor of the 2015 Think Pink Tea i ill be el on T urs a t rom m at t e labama Cruise Terminal

FATHER’S DEATH

Inspiration for Philanthropy

44

ilborn s interest in an er resear an treatment as in le b is at er s eat rom an reati an er in T e el er ilborn as onl ears ol at t e time, and died a mere four months after his diagnosis.

in e ilborn s ilant ro to ar t e Mitchell Cancer Institute didn’t start with the Think Pink Tea event.

ilborn sai o is at er M at er ave me a love o t e la a ne e u ation an em at or ot er eo le ilborn re its t ese ir umstan es it rovi in im t e means an abilit to ive aritabl to MCI

earl a e a e a o in ilborn reate a research scholar fund at the University of South labama to train to o tors an resear ers at the Mitchell Cancer Institute.

ra uate o rin ill Colle e in Mobile ilborn received a law degree from the University of labama ool o a an a master s in la rom New York University.

Minds Conquering Cancer | Fall 2015

Dr. Michael Finan, Margaret Sullivan, Kelly McCarron, Travis Goodloe, Dawn Pilot and Linda Lou Parsons.

POINT CLEAR CHARITIES SUPPORTS

Early Detection Program In January, Mitchell Cancer Institute was one of two major beneficiaries from Point Clear Charities (PCC), proceeds of the 2014 Polo ^ at the Point and Fairhope Fete . A total of 19 worthy local nonprofit organizations benefitted from these successful events.

MCI received $58,000 toward its early detection cancer research program. Scientific teams working at MCI have established a non-invasive approach to collect fluids for the detection of highly specific protein biomarkers produced by pancreatic and ovarian cancers. These funds will support MCI’s efforts to refine and validate the best set of biomarkers that could eventually become a clinical screening test.

“This was another great year for Fairhope Fete^ and Polo at the Point. It takes a lot of commitment from generous sponsors, supporters, international polo

players, merchants, dedicated committee members and volunteers to make these events a success,” 2014 Chairwoman Linda Lou Parsons said. “What a fine definition of community it is, when so many come together to create such festivities, all while supporting such worthy causes in our community,” PCC Inc. has been a longtime friend of the USA Mitchell Cancer Institute. Since 1988, its signature event, Polo at the Point, has raised millions of dollars for cancer research, local nonprofit organizations and children’s charities.

MCI is grateful to Travis Goodloe, PCC Inc. president, Dawn Pilot and Linda Lou Parsons, co-chairs of Polo at the Point, and the hundreds of volunteers who made this gift possible.

T e

olo at t e oint

ill be el on e t

Minds Conquering Cancer | Fall 2015

45

DEVELOPMENT SUCCESSFUL GO RUN RAISES FUNDS FOR

Gynecologic Cancer The seventh annual GO Run on Sept. 20, 2014, was a huge success, generating over $78,000 for gynecologic cancer research for the Mitchell Cancer Institute.

Presented by the Catranis Family Charitable Foundation, the 5K and 1-mile Fun Run drew 1,000 participants. Afterward, they enjoyed a variety of food, music, children’s activities, vendor tents, free massages and the awards ceremony. Dr. Marcus Tan and his team were also available to conduct skin screenings.

The GO Run, which stands for gynecologic oncology, has grown dramatically since its inception in 2008. The 2015 GO Run, presented b t e Catranis amil C aritable oun ation ill be el e t at the University of South labama Moulton To er & Alumni Plaza. For more information, call or visit www.usamci.com/gorun.

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Minds Conquering Cancer | Fall 2015

Upcoming

EVENTS 09.19.15

11.01.15

8th Annual

GO RUN at the Mitchell Center/Moulton Tower Lawn on USA Main Campus. To register or learn more visit www.usamci.com/gorun.

Tennis for Tatas at Mobile Tennis Center ll mone raise oes to breast an er resear at MCI or more in ormation onta t ori au ier at or sau ier sout alabama e u

09.26.15

11.19.15

Polo at the Point at Sonny Hill-Clearwater Polo Complex in Point Clear. For more information visit www.poloatthepoint.com.

10.08.15

rom

Think Pink Tea m at t e labama Cruise Terminal

10.17.15 4th Annual

Salty Worm Brackish Classic and Delta Bash at lue ill estaurant ene ts t e aillar Pancreatic Cancer Research Endowment. For more information contact Kori Saucier at or sau ier sout alabama e u.

t

nnual

Celebrate Hope at Mitchell Cancer Institute usam i om elebrate o e

05.12.16 4th Annual

Hope Cup Golf Tournament at Countr Club o Mobile ww.usahealthsystem.com/hopecup

06.05.16

National Cancer Survivors Day Celebration at t e labama Cruise Terminal

Non-Profit Non-Profit U.S. Postage Postage U.S. PAID PAID Mobile, AL AL Mobile, Permit No. No. 506 506 Permit

USA Mitchell Mitchell Cancer Cancer Institute Institute USA 1660 Springhill Springhill Avenue Avenue 1660 Mobile, AL AL 36604-1405 36604-1405 Mobile,

For appointments appointments call: call: For (251) 665-8000 665-8000 or or (251) 1-800-330-8538 1-800-330-8538 To learn learn more more about about our our To clinical services services see see our our website: website: clinical www.usamci.com www.usamci.com

­­

UpCOMINg MCI EVENTS September 17, 2011

4th Annual GO for Gynecologic Oncology 5K/1 Mile Fun Run/Walk 8:00 a.m.

USA Main Campus Mitchell Center Lawn Benefits GYN cancer research

October 23, 2011

2nd Annual Tennis for Tatas 1:00 p.m.

Mobile Tennis Center Benefits breast cancer research

October 27, 2011 October 18, 2011

5th Annual Eastern Shore Toyota and Eastern Shore Hyundai Golf Tournament 11:00 a.m.

Timbercreek Golf Club Daphne, Alabama Benefits Shawn and Leyla Esfahani Breast Cancer Research Endowment

Stay connected to the MCI. Scan with your smartphone or visit us at www.usamci.com (Download aa free free QR QR code code reader reader application) application) (Download

follow us on facebook: USA Mitchell Cancer Institute

2nd Annual Think Pink Tea 4 – 6 p.m.

Mitchell Cancer Institute Co-sponsored by Infirmary Health System

November 17, 2011

3rd Annual Celebrate Hope gala 6:00 p.m.

Mitchell Cancer Institute Benefits cancer research

for more information on how you can sponsor, participate or volunteer for MCI Special Events, please contact Abbie McCullough at 251-460-7032 To learn more about amccullough@usouthal.edu MCI visit www.usamci.com or e-mail Visit our Website: www.usamci.com/specialevents