5051 Centre Avenue Project

DRIVING THE

FUTURE OF

INNOVATION

5 0 5 1 C E N T R E A V E N U E LABS + OFFICES + RETAIL

LAB + OFFICE + RETAIL 5051 CENTRE AVENUE

PROPOSED SITE PLAN

Proposed development site in Pittsburgh's Bloomfield neighborhood.

PROJECT OVERVIEW

The historic building that once housed the Ford Motor Company in Pittsburgh’s Bloomfield neighborhood is getting new life as a world-class hub that combines research, innovation and entrepreneurship.

Driven by a collaboration between the University of Pittsburgh and Wexford Science+Technology, the property at the corner of Baum Boulevard and Morewood Avenue will encourage collaboration between researchers and entrepreneurs to advance their discoveries into patient treatment. The results could reinvent the way health care is delivered in such areas as transplantation, cancer and immunology.

Part of this space will include researchers supported by UPMC’s Immune Transplant and Therapy Center (ITTC), which focuses on cutting-edge medical research for the latest immunotherapies.

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AMENITIES OF THE RENOVATED BUILDING WILL INCLUDE: • State-of-the-art lab space for researchers.

• Meeting rooms for researchers and administrators along with flexible lounge areas to spur collaboration.

• Three retail storefronts.

• Tiered parking garage with secured bike parking room.

• Auditorium with 250+ seat capacity for lectures, presentations and symposiums.

• Multipurpose atrium and event space.

• Galleries throughout to highlight the building’s rich heritage.

The development is expected to open in fall 2021. The labs within the eight-story space will reflect input gathered from researchers.

Main entry plaza and retail on Centre with addition above.

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ATRIUM

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ABOUT THE BUILDING:

Built in 1915 by Ford Motor Co. as a one-stop shop for the iconic Model T’s, which went from assembly line to showroom floor, all in the same building.

Eight stories and 200,000+ square feet.

Listed on the National Register of Historic Places.

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MAKING A DIFFERENCE Our strengths in research are the engine that can lead to great things: life-saving, life-changing treatments and cures, but also jobs and economic growth as we work to get our discoveries out into the world.

PROJECT TEAM University of Pittsburgh • Business and Operations—Functions include facilities management, planning and real estate, public safety and auxiliary services departments.

“This initiative—and this

incredible partnership with UPMC and the business community—is about building the right ecosystem to tackle some of medicine’s greatest challenges. It is both a bold look into the future of immunotherapy and a historic commitment—one that will decisively advance the University of Pittsburgh’s long legacy

• Office of Economic Partnerships—Enhances the University’s mission and increases its ability to connect with the global economy and accelerate growth in the regional economy.

Wexford Science+Technology Development company exclusively focused on partnering with universities, academic medical centers and research institutions to create vibrant, mixed-use communities built on a foundation of discovery, innovation and entrepreneurial activity.

ZGF Architects Architecture, design and planning firm with an intentionally diverse portfolio, including health care and research facilities, academic buildings, mixed-use developments, corporate campuses, museums, transportation facilities and ecodistricts.

of leveraging knowledge for society’s gain.

”

—Patrick Gallagher Chancellor, University of Pittsburgh

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PERSONALIZED THERAPIES UPMC and Pitt envision a day when Pittsburgh is the world’s destination for immune transplant and therapy. The goal of the UPMC Immune Transplant and Therapy Center researchers is to: • Advance the science of immunotherapy.

• Improve the longevity and quality of life for patients around the world.

• Become a global knowledge leader in immune transplant and therapy.

The initial focus in this building will be on transplantation, cancer and immunology.

“We are positioned to use

our intelligence, and our skill, and our wisdom, our analytical ability to in fact, generate new ways to prevent illness and treat illness, and thereby contribute not only to our own city but to

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the world itself.

—Arthur Levine Senior Vice Chancellor for the Health Sciences, University of Pittsburgh

P R O J E C T T E A M , continued Turner Construction International construction services company undertaking large, complex projects; fostering innovation; embracing emerging technologies; and making a difference for its clients, employees and communities.

Ventas Health care real estate capital provider that partners with leading care providers, developers, research and medical institutions, innovators and health care organizations. Ventas’ success is buoyed by the strong demographic trends of an aging population and increased life expectancy.

Bank of America Multinational investment bank and financial services company that is committed to using its capabilities to help clients be financially successful, with a focus on strengthening communities and delivering value to shareholders.

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COMMON SPACE

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PROJECT TIMELINE

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• •

“Buildings like this really are

the lifeblood of communities.

• •

They provide jobs for those in the neighborhood and distribute innovations. We’ve seen Pittsburgh making those top 10 lists, so we look forward in our partnership with Pitt and UPMC to be the top place

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for innovation.

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—Joseph Reagan, Jr. Northeast Region Executive, Senior Vice President, Wexford Science+Technology

• •

February 2018: Pitt and UPMC announce plans to include Immune Transplant and Therapy Center research within the historic building July 2018: The Property and Facilities Committee of Pitt’s Board of Trustees approves the intended purchase of the building from UPMC and hiring of Wexford Science+Technology as developer November 2018: Pitt closes on the purchase of the building from UPMC April 2019: First visible work begins with the demolition of an adjacent building May 2019: Pitt and Wexford formally execute development agreement June 2019: Wexford elects to proceed with construction of 108,000-square-foot speculative lab/office addition February 2020: Erect tower crane for rooftop steel construction Fall 2021: Development to open for business

LAB AND OFFICE SPACE

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PRINCIPAL RESEARCHERS Robert L. Ferris, MD, PhD Director, UPMC Hillman Cancer Center; Associate Vice Chancellor for Cancer Research, Health Sciences; Hillman Professor of Oncology; Professor of Otolaryngology, of Immunology, and of Radiation Oncology, School of Medicine, University of Pittsburgh As a physician-scientist, Dr. Ferris seeks to further develop and implement immunotherapy, which stimulates the body’s immune system to eliminate and suppress cancer.

Fadi G. Lakkis, MD Frank and Athena Sarris Chair in Transplantation Biology; Distinguished Professor of Surgery; Professor of Immunology and Medicine; Scientific Director, Thomas E. Starzl Transplantation Institute, University of Pittsburgh The goal of Dr. Lakkis’ research is to understand the fundamental mechanisms of acute and chronic rejection in solid organ transplantation.

Mark Jay Shlomchik, MD, PhD UPMC Endowed and Distinguished Professor; Chair, Department of Immunology, University of Pittsburgh Dr. Shlomchik is known for his world-leading research in systemic autoimmune diseases and B cell immune responses and memory.

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DESIGN OVERVIEW

Level 1 (pictured above) will feature collaboration space, conference rooms, retail and a large auditorium for lectures and presentations.

Level 2 (inset) is being designed as lab and office space for researchers.

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AUDITORIUM AND CONFERENCE ROOMS

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Office of University Communications and Marketing 400 Craig Hall 200 South Craig Street Pittsburgh, PA 15260 communications@pitt.edu

14112362-0220