Syllabus

University of Veterinary Medicine Budapest, Hungary

Syllabus

CONTENTS 1ST SEMESTER. . . . . . . . . . . . . . . . . . . . . . . . . . 3

7TH SEMESTER . . . . . . . . . . . . . . . . . . . . . . . . 52

Anatomy 1. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 Biology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 Biophysics. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 Chemistry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 Histology 1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 Informatics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 Zoology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16

Internal medicine 1 . . . . . . . . . . . . . . . . . . . . . . . . . .

Obstetrics and reproduction 1. . . . . . . . . . . . . . . . .

Parasitology 2. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Pathology C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Surgery 2.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Toxicology. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

2

ND

SEMESTER . . . . . . . . . . . . . . . . . . . . . . . . 17

Animal welfare. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Biomaths. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Botany . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Histology 2 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Veterinary- and food chemistry. . . . . . . . . . . . . . . .

18 20 22 24 26

3RD SEMESTER . . . . . . . . . . . . . . . . . . . . . . . . 28 Agroeconomics. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Anatomy 3. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Animal breeding.. . . . . . . . . . . . . . . . . . . . . . . . . . . .

Veterinary biochemistry 1. . . . . . . . . . . . . . . . . . . . .

Veterinary physiology 1. . . . . . . . . . . . . . . . . . . . . . .

Veterinary profession.. . . . . . . . . . . . . . . . . . . . . . . .

29 30 32 34 36 38

4TH SEMESTER . . . . . . . . . . . . . . . . . . . . . . . . 39 Animal breeding.. . . . . . . . . . . . . . . . . . . . . . . . . . . .

Topographic and applied anatomy . . . . . . . . . . . . .

Veterinary biochemistry 2. . . . . . . . . . . . . . . . . . . . .

Veterinary physiology 2. . . . . . . . . . . . . . . . . . . . . . .

Veterinary virology.. . . . . . . . . . . . . . . . . . . . . . . . . .

40 42 44 47 49

5TH SEMESTER . . . . . . . . . . . . . . . . . . . . . . . . 51 Applied Ethology. . . . . . . . . . . . . . . . . . . . . . . . . . . .

General pathology . . . . . . . . . . . . . . . . . . . . . . . . . . .

Laboratory Animal Science & Bioethics. . . . . . . . .

Veterinary bacteriology. . . . . . . . . . . . . . . . . . . . . . .

Veterinary Laboratory Diagnostics. . . . . . . . . . . . .

Veterinary Pathophysiology. . . . . . . . . . . . . . . . . . .

Veterinary pharmacology 1. . . . . . . . . . . . . . . . . . . .

52 55 58 60 62 64 66

6TH SEMESTER . . . . . . . . . . . . . . . . . . . . . . . . 69 Animal Nutrition 1. . . . . . . . . . . . . . . . . . . . . . . . . . .

Equine Medicine and Surgery 1 . . . . . . . . . . . . . . .

Small Animal Medicine 1. . . . . . . . . . . . . . . . . . . . .

Parasitology 1. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Pathology 1. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Veterinary Immunology . . . . . . . . . . . . . . . . . . . . . .

Veterinary pharmacology 2. . . . . . . . . . . . . . . . . . . .

70 73 75 77 79 81 83

86 90 91 93 95 97

8TH SEMESTER . . . . . . . . . . . . . . . . . . . . . . . . 99 Animal hygiene and herd health 1. . . . . . . . . . . . .

Avian and exotic animal medicine. . . . . . . . . . . . .

Bee hygiene and health. . . . . . . . . . . . . . . . . . . . . .

Fish hygiene and diseases. . . . . . . . . . . . . . . . . . . .

Internal medicine 2 . . . . . . . . . . . . . . . . . . . . . . . . .

Laboratory animal science and bioethics. . . . . . .

Obstetrics and reproduction 2. . . . . . . . . . . . . . . .

Pathology D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Surgery 3 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

100 102 103 104 105 107 109 112 114

9TH SEMESTER . . . . . . . . . . . . . . . . . . . . . . . 117 Animal hygiene and herd health 2. . . . . . . . . . . . . 118 Epidemiology and infectious diseases 1. . . . . . . . 122 Food hygiene 1.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 124 Internal medicine 3 . . . . . . . . . . . . . . . . . . . . . . . . . 126 Obstetrics and reproduction 3. . . . . . . . . . . . . . . . 128 Ophthalmology. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 132 State veterinary medicine 1. . . . . . . . . . . . . . . . . . .134

10TH SEMESTER. . . . . . . . . . . . . . . . . . . . . . 135 Animal health economy management. . . . . . . . . .

Epidemiology and infectious diseases 2. . . . . . . .

Food hygiene 2. . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Forensic veterinary medicine. . . . . . . . . . . . . . . . .

State veterinary medicine 2.. . . . . . . . . . . . . . . . . .

136 137 139 141 142

SYLLABUS

1ST SEMESTER

3

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

ANATOMY 1 1st Semester Course description Course

Anatomy 1

Department Language

English

Nature

Mandatory

Year/semester

1st year, winter-term

Credits (ECTS)

5

Lectures (hour/semester)

30

Plenary lectures (hour/semester) Practicals (hour/semester)

45

Responsible teacher

Prof. Dr. Sótonyi Péter

Teacher(s)

Dr. Szalay Ferenc, Dr. Heinzlmann Andrea, Dr. Hazai Diana, Dr. Reinitz László, Dr. Kapiller Mátyás, Dr. Kondor Milán

Prerequisites

Learning outcome (include skills and competencies, if any) Students got aquainted with basics of anatomy and the locomotor apparatus of domestic mammals (Car, Eq, Ru, Sus), got the basic routine in dissecting fresh cadavers and handling formaline fixed specimen.

Outcome assessment Practical exam on 2x20 specimen; 20 on bones (including skeleton) and formaline fixed limbs (Eq, Ca), 20 on fresh, dissected cadavers. 11 good answers (55%) is requiered in both topics independently.

Theoretical exam: written test, single choice, multiple, choice, short answers. Passing grade: 55%

4

SYLLABUS

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Introduction: the history of anatomy, Anatomical terminology: planes, directions, regions Regions of the body

Week 2

Bones of the trunk Bones of the trunk

Week 3

Bones of the forelimb Bones of the forelimb

Week 4

Bones of the hindlimb Bones of the hindlimb

Week 5

Neurocranium Neurocranium

Week 6

Viscerocranium Neurocranium

Week 7

General arthology and myology Basics of the dissection

Week 8

Muscles and joints of the forelimb

Week 9

Muscles and joints of the forelimb

Week 10

Muscles and joints of the hindlimb

Week 11

Muscles and joints of the hindlimb

Week 12

Respiratory and abdominal muscles

Week 13

Muscles of the head, neck and trunk

Week 14

Statics and dynamics, the meat as food. Demonstration.

WEEK

Practical topics

Week 1

Regions of the body

Week 2

Bones of the trunk

Week 3

Bones of the forelimb

Week 4

Bones of the hindlimb

Week 5

Neurocranium

Week 6

Viscerocranium

Week 7

Midterm

Week 8

Muscles and joints of the forelimb

Week 9

Muscles and joints of the forelimb

Week 10

Muscles and joints of the hindlimb

Week 11

Muscles and joints of the hindlimb

Week 12

Respiratory and abdominal muscles

Week 13

Muscles of the head, neck and trunk

Week 14

Practical exam

Recommended literature König-Liebich: Veterinary Anatomy of Domestic Mammals: Textbook and Colour Atlas; Nickel, Schummer, Seiferle: Anatomy of the Domestic Animals; Dyce, Sack, Wensing: Textbook of veterinary anatomy; Constantinescu: Illustrated Veterinary Anatomical Nomenclature; Evans-deLahunta: Miller’s Anatomy of the Dog; Evans-deLahunta: Guide to the dissection of the Dog; Sótonyi Péter: Anatomia Canis CD-ROM; Budras: Anatomy of the Dog, An Illustrated Text; Budras: Anatomy of the Horse;

5

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

BIOLOGY 1st Semester Course description Course

Biology

Department

Departmen of Anatomy and Histology

Language

English

Nature

Mandatory

Year/semester

1st year, winter-term

Credits (ECTS)

3

Lectures (hour/semester)

30

Plenary lectures (hour/semester) Practicals (hour/semester)

0

Responsible teacher

Dr. Bence Rรกcz

Teacher(s)

Prof. Katalin Halasy, Dr. Bence Rรกcz

Prerequisites

Learning outcome (include skills and competencies, if any) The subject is divided into three parts in order to improve the bases obtained at high-school and generate new fields. The first part is about the genetical code and its structure. The second part is about the general anatomy of the cell. In the third part, we introduce the development of the embryo until the formation of the body. On completion of the first two modules students will have a fundamental knowledge of cell and molecular biology. In addition, students will get aquainted with basic techniques that can be applied in cell and molecular biology. This knowledge will help students understand cell function in disease and development. In the third module of the subject, students will be introduced into comparative embriology with special focus on domestic mammals and birds. On completion of this module students will have a clear understanding of the reproductive cycle and relate it to the reproductive organs, will be able to describe the processes of conception, pregnancy, gastrulation and early foetal development.

Outcome assessment End of Semester 1 hour MCQ written test. No midterms.

6

SYLLABUS

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Cytology

Week 2

Cytology

Week 3

Cytology

Week 4

Cytology

Week 5

Cytology

Week 6

Cytology

Week 7

Cytology

Week 8

The gametes, The structure of the avian egg

Week 9

Cleavage, Gastrulation

Week 10

Sexual cycle, oestrus, fertilization, pregnancy, determination of sex

Week 11

Differentiation of the germinal disc, Derivatives of the germinal layers

Week 12

Folding of the embryo, Migration and implantation

Week 13

Extraembrionic membranes, chorion

Week 14

Placenta types

Recommended literature Lecture notes available in pdf format.

Note(s) At certain points in the course it may make good sense to modify the schedule outlined above.

Teachers reserve the right to modify elements of the course and will notify students accordingly.

7

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

BIOPHYSICS 1st Semester Course description Course

Biophysics

Department Language

English

Nature

Mandatory

Year/semester

1st year, winter-term

Credits (ECTS)

3

Lectures (hour/semester)

30

Plenary lectures (hour/semester) Practicals (hour/semester)

0

Responsible teacher

Zoltán Szőkefalvi-Nagy

Teacher(s) Prerequisites

Learning outcome (include skills and competencies, if any) In the Biophysics course lectures are given in selective topics of physics having important biological and medical connections. Completing the course students will be more informed in the physical background of certain biological, life and physiological processes, as well. They knowledge of physical basis of the operation of medical instruments used in diagnostics and practical medical treatments will also be enlarged.

Outcome assessment At the end of the semeter there are oral final examinations from the whole content of the course.

At the examination students have to draw 1 topic-card, the headwords listed on it serve only as guides to help the on-the-spot preparation. Questions for any related topics have to be expected!

The use of reference tables, smart phones, calculators or any other aids is strongly prohibited.

The mark is emerging during the personal conversation. In the case of lack of any knowledge a second topic-card can be chosen but students have to answer the exminer’s topics related questions promptly, without any preparation.

8

SYLLABUS

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Measurements, physical quatities, units, errors of a measurement, error propagation.

Macro-transport processes: flow of fluids I, ideal fluids

Week 2

Flow of fluids II. viscous fluids, flow in the circulatory system, viscous drag force, fall in viscous fluid

Week 3

Micro-transport processes, Diffusion, osmosis, transport across membranes, facilitated diffusion, activetransport, sedimentation

Week 4

Ultracentrifugation. Physics and applications of light (electromagnetic waves): geometric optics, light reflection, light refraction, total reflection, refraction in planparallel slab, refraction on prism, dispersion of light

Week 5

Optical image formation, plane mirror, optical lenses, the ray tracing technique, thin lens equation, thick lenses, the human eye,visual acuity, colour perception, optical defects invision, the simple magnifier, the compound microscope

Week 6

Wave (or physical) optics, principle of superposition, interference, Huygens-Fresnel principle, light diffraction, resolving power of optical devices, the Abbe criterion, special microscopes

Week 7

Matter waves, transmission and scanning electron microscopes, the photoelectric effect, light-matter interaction, scattering, absorption, light attenuation in matter

Week 8

Principle and properties of lasers. Production, properties and effects of X-rays, the X-ray spectra, attenuation of X-rays in matter, photo effect, Compton effect, pair production

Week 9

Electric properties of living substances: passive and active properties, the formation and properties of the resting membrane potential, Nernst equations, Na-K pump, response to weak stimulus, the action potential and its propagation

Week 10

Measurement of the membrane potential. Body surface biopotentials: ECG, EEG, the cathode-ray oscilloscope, high frequency heat generation (electric diathermy)

Week 11

Basics of nuclear physics and nuclear radiations: natural radioactivity, composition of a nucleus, isotopes, binding energy, radioactive decay law, half-time, radio-carbon dating, nuclear reactions, chain reactions, transmission of nuclear radiation through matter

Week 12

Dosimetric units, biological effects of ionising radiations, basic principles of radiation protection, radiation detectors

Week 13

The radioactive tracer method and its applications. Modern imaging techniques in medicine, image formation using radiactive isotopes,thermography

Week 14

Ultrasound and its medical applications, Doppler effect, echo encefalography, X-ray tomography, positron emission tomography (PET), magnetic resonance imaging (MRI)

Recommended literature The presentations of the lectures in pdf format available from the website http://www.rmki.kfki.hu/~sznagy/jegyzetek (user ID: hallgató, password: 12345X) S. Damjanovich – J. Fidy – J. Szöllősi: Medical Biophysics, Medicina Könyvkiadó Rt., 2009 ISBN: 9789632262499 Morton M. Sternheim and Joseph W. Kane: General Physics, Wiley, 1991, ISBN 0-471-53401-3

9

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

CHEMISTRY 1st Semester Course description Course Department Language Nature Year/semester Credits (ECTS) Lectures (hour/semester) Plenary lectures (hour/semester) Practicals (hour/semester) Responsible teacher Teacher(s) Prerequisites

Chemistry Department of Chemistry English Mandatory 1st year, winter-term 5 30 30 Dr. Zoltán Vincze Dr. Zoltán Vincze, Dr. Tamás R. Varga, Dr. Mihály V. Pilipecz, Anna Alekszi-Kaszás

Learning outcome (include skills and competencies, if any) Be able to describe the fundamental scientific principles in the subfields of general, analytical and inorganic chemistry and apply these principles to problems.

Be able to integrate and apply relevant knowledge to problems that emerge from the broader interdisciplinary subfields of biological and veterinary sciences. Be able to carry out, record and analyze the results of chemical experiments.

Outcome assessment 1) Supervisors will randomly check preparedness of the students with a short written test in the lab three times during the term. The subject is the topic of the current lab. With these short tests the students can collect 3x5=15 points.

2) Midterm Tests. During the term all students are obliged to perform two written tests (60 min./ test), whose subject includes the topics of the laboratory exercises and the related lectures.

Test 1: Chemical calculations (stoichiometry) (15 points), Test 2: pH calculations (15 points) The tests cannot be later upgraded. Only those students who missed the midterm test(s) due to documented illness are obliged to write a make-up test(s). The make-up test(s) topics include the subjects of the missed test(s). The results of any test will be announced within 3 working days from the writing date. Smartphones, graphic calculators, netbooks, tablets and other text storage electronic devices are not allowed to use during the tests/exams. Cheating, plagiarism or use the above mentioned devices are not tolerated (0 point), and the incidence will be promtly reported to Department of Student Affairs.

3) Titrations. The submitted results of two titrations (i.e. analytical determination of massconcentrations of NaOH and FeSO4) in exercises No. 10 - 11 will be evaluated with 0 - 5 points/ titration (0 - 10 points overall).

4) End-of-term Examination. The Winter-term has to be closed with a 120 min. written examination with 100 points, which includes all subjects of lectures and laboratory exercises (General-, and Inorganic Chemistry) except calculations. To pass Chemistry, minimum 50 points of the exam must be achieved despite of the overall points. The grade will be determined by the sum of points from the midterm-, and lab tests, and examination (155 points overall) as follows: Points Grade, 0 - 76 unsatisfactory (1), 77 – 96 pass (2), 97 – 115 fair (3), 116 – 135 good (4), 136 - 155 excellent (5) To help the study consultations will be organized according to the agreement with the students. The consultation is not a simple repetition of the lectures but it can give help to understand the difficult parts of the subject and guidelines in preparation for the midterm tests. The exact date of these sessions will be announced in time.

10

SYLLABUS

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Inorganic chemistry. Periodic table Atomic Structure, Atom models Basic principles of wave mechanics

Week 2

Molecular orbitals. Exeptions to the octet rule. Electronegativity. Polar covalent bonding. Molecular geometry. Intermolecular attractions

Week 3

Reaction equations. Hydrogen. Halogens. Covalent bond. Halo compounds. Oxygen, oxides, oxyacids

Week 4

Sulfur and S-compounds. Nitrogen and N-compounds. Phoshorus and P-compounds.

Carbon, and their compounds. Metals and their compounds. Complexes.

Week 5

States of Matter

Week 6

Solutions

Week 7

Reaction kinetics. Homogenous and heterogeneous equilibria

Week 8

Acid-base equilibria

Week 9

Buffers. Hydrolysis of salts

Week 10

Chemical thermodyn. 1st law. Entropy. Spontaneous proc. Gibbs free energy, 2nd law, chem. Thermodyn. And equlibria

Week 11

Electrochemistry

Week 12

Colloids

Week 13

Colloids. Methods of Chromatography I.

Week 14

WEEK

Practical topics

Week 1

Introduction

Week 2

Basic laboratory techniques 1

Week 3

Basic laboratory techniques 2

Week 4

Inorganic chemistry 1

Week 5

Inorganic chemistry 2

Week 6

Inorganic chemistry 3

Week 7

Seminar (no manual work)

Week 8

Rate of chemical reactions

Week 9

Chemical equilibria

Week 10

Acid-base equilibrium. Potentiometric

Week 11

Titration I. (acidi-alkalimetry)

Week 12

Titration II: (redoximetry)

Week 13

Preparation and properties of colloids

Week 14

Make-up lab.

Recommended literature Raymond Chang, Ken Goldsby: Chemistry, McGraw-Hill Inc., 11th edition, 2012

11

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

HISTOLOGY 1 1st Semester Course description Course

Histology 1

Department Language

English

Nature

Mandatory

Year/semester

1st year, winter-term

Credits (ECTS)

5

Lectures (hour/semester)

30

Plenary lectures (hour/semester) Practicals (hour/semester)

30

Responsible teacher

Dr. Bence Rácz

Teacher(s)

Prof. Katalin Halasy, Dr. Bence Rácz

Prerequisites

Learning outcome (include skills and competencies, if any) On completion of Histology 2 students will have knowledge and understanding of the structural and functional organization of the various organs that can be found in domestic mamals and avian species. In addition, students should be able to relate cellular structure to complex tissue organization and function.

Outcome assessment End of Semester 1 hour MCQ written test. Practical exam to assess microscopy based laboratory skills. No midterms.

The completed ‘Histology practical workbook’ must be presented at the end of the semester.

Practical exam: students must recognize the basic tissue types in two non-labeled slides.

12

SYLLABUS

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Introduction. History of histology

Week 2

Histotechnics – methods in histology

Week 3

The light and electron microscope

Week 4

Epithelial tissues I. – Surface epithelia

Week 5

Epithelial tissues II. – Glandular epithelia

Week 6

Connective tissues I.

Week 7

Connective tissues II.

Week 8

Supportive tissues – cartilage and bone

Week 9

Osteogenesis

Week 10

Muscle tissues

Week 11

Neural tissue

Week 12

Blood

Week 13

Hematopoiesis

Week 14

Blood vessels

WEEK

Practical topics

Week 1

Introduction. The light microscope

Week 2

Special light microscopes

Week 3

Histotechnics – methods in histology

Week 4

The transmission electron microscope (TEM)

Week 5

Epithelial tissues I.

Week 6

Epithelial tissues II.

Week 7

Connective tissues I.

Week 8

Connective tissues II.

Week 9

Supportive tissue

Week 10

Osteogenesis

Week 11

Muscle tissues

Week 12

Neural tissue

Week 13

Mammalian and avian blood

Week 14

Blood vessels

Recommended literature Dellmann: Textbook of veterinary histology

Note(s) At certain points in the course it may make good sense to modify the schedule outlined above.

Teachers reserve the right to modify elements of the course and will notify students accordingly.

13

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

INFORMATICS 1st Semester Course description Course

Informatics

Department

Biomathematics and Informatics

Language

English

Nature

Mandatory

Year/semester

1st year, winter-term

Credits (ECTS)

3

Lectures (hour/semester)

15

Plenary lectures (hour/semester) Practicals (hour/semester)

30

Responsible teacher

Abonyi-Tóth Zsolt

Teacher(s)

Abonyi-Tóth Zsolt, Fehérvári Péter, Kövér Szilvia, Piross Imre Sándor, Vili Nóra

Prerequisites

Learning outcome (include skills and competencies, if any) Ability of analyzing data and writing a science paper or thesis, creating a presentation.

Outcome assessment Excel and R Commander midterm, multiple choice test about the lectures, 3 homeworks: CV, presentation, science paper

14

SYLLABUS

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Introduction

Week 2

Spreadsheets

Week 3

Spreadsheets

Week 4

Spreadsheets

Week 5

Spreadsheets and statistical calculations

Week 6

Presentations

Week 7

Word processing

Week 8

Word processing

Week 9

Word processing

Week 10

Word processing

Week 11

Data protection

Week 12

Data protection

Week 13

Graphics

Week 14

Graphics

WEEK

Practical topics

Week 1

Word basics: Writing a CV

Week 2

Excel basics

Week 3

Excel and R Commander data analysis 1 - quantitative variables

Week 4

Excel and R Commander data analysis 2 - qualitative variables

Week 5

Excel and R Commander data analysis 3 - quantitative variables by groups

Week 6

Excel pivot tables, INDEX, MATCH, R Commander data filter

Week 7

Powerpoint

Week 8

MIDTERM

Week 9

Word styles, table of content

Week 10

Word pictures, captions, cross references, header/footer

Week 11

Word footnotes, tables, symbols, review tools, Zotero

Week 12

Word tabulators

Week 13

Presentations

Week 14

Presentations, final test, re-take

15

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

ZOOLOGY 1st Semester Course description Course Department Language Nature Year/semester Credits (ECTS) Lectures (hour/semester) Plenary lectures (hour/semester) Practicals (hour/semester) Responsible teacher Teacher(s) Prerequisites

Zoology Parasitology and Zoology English Mandatory 1st year, winter-term 3 28 0 0 Dr. Sándor Hornok Dr. Sándor Hornok, Dr. Sándor Szekeres

Learning outcome (include skills and competencies, if any) The course provides basic knowledge on the systematics of animal taxa, which will be important in later subjects, such as parasitology and epidemiology. In addition, principles of evolution biology, ecology, population dynamics and ethology will also be covered.

Outcome assessment Written exam during the exam period. Three exam dates will be given after consultation with the students. On the exam 84 multiple choice (1 of 4) questions will be asked which are based on the lectures and lecture notes.

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1 Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8 Week 9 Week 10 Week 11 Week 12 Week 13 Week 14

Introduction. General zootaxonomy Major taxa of Kingdom Animalia Protozoa („Sarcomastigophora”, Apicomplexa, Microspora, Ciliophora) Porifera, Myxozoa, Cnidaria, Platyhelminthes Nematoda, Annelida, Mollusca Vertebrata I. (”Pisces”, Amphibia) Vertebrata II. (Reptilia, Aves) Vertebrata III. (Mammalia) Arthropoda I. (Myriapoda, Chelicerata) Arthropoda II. (Hexapoda I.) Arthropoda III. (Hexapoda II.) Echinodermata Microevolution Macroevolution, speciation. Evolution of infectious agents Basic terms in ecology. Population ecology Community, ecosystem, biosphere Ethology

Recommended literature Lecture notes (availatbe at http://parazitologia.univet.hu/) 16

SYLLABUS

2ND SEMESTER

17

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

ANIMAL WELFARE 2nd Semester Course description Course

Animal welfare

Department Language

English

Nature

Mandatory

Year/semester

1st year, spring-term

Credits (ECTS)

3

Lectures (hour/semester)

30

Plenary lectures (hour/semester) Practicals (hour/semester)

15

Responsible teacher

Kinga Fodor DVM PHD, associate professor

Teacher(s)

Fekete Sándor György, DVM, DSc, professor Korsós Gabriella DVM, assistant research fellow

Prerequisites

Learning outcome (include skills and competencies, if any) There is a strong connection between animal protection (welfare) and veterinary science.

The assessment of animal welfare has a key role in preventing and recognizing various diseases.

Veterinarians are the professional protectors of the animals so beyond curing different diseases they must also protect the various animals from unnecessary suffering, regardless of the area in which they will work in the future in veterinary medicine.

After absolving the subject, students will have the essential knowledge about the most important animal protection laws and the basics of animal behaviour in order to be able to make a genuine judgement on the welfare of an animal.

They get insights into the day-to-day work of shelters, get to know the inside of zoos and circuses.

They have a thorough understanding of all areas of animal husbandry that constitute a priority and a risk area for animal protection: hunting, animal testing, circuses, etc.

They will be able to write a reliable animal welfare expert’s opinion on an animal protection case.

Outcome assessment written essay + written exam (test)

18

SYLLABUS

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Definitions: animal welfare, wellbeing, rights and protection.

The concept, goals and task of professional animal protection.

Week 2

Relationship between animal and environmental protection. Wildlife protection

Week 3

Protection of companions, pets and animals kept for experimental purposes

Week 4

Protection of companions, pets and animals kept for experimental purpose

Week 5

Abnormal animal behaviours.

Week 6

The effect of behaviour restriction on animal welfare (cages, keeping chains, crate, boredom, training etc.)

Week 7

Recognition, prevention and alleviation of animal pain and estimation of the degree of suffering. Relationship between animal abuse and social aggression.

Week 8

Areas of the human-animal relationship.

Week 9

Protection of animals kept for farming purposes

Week 10

Protection of animals during transport

Week 11

Legal aspects of euthanasia; Legal sanctions in the field of animal welfare

Week 12

New approach to evaluate the animal welfare using cognitive test

Week 13

Animal models in human disease research. Bioethics.

Week 14

How to educate animal protection on from kindergarten to adult education

WEEK

Practical topics

Week 1

Interpretation of media articles and events. Expertise on fields of animal protection.

Week 4

Dogs: special species, special problems (domestication- adaptation to human life, zoonosis, overpopulation, breeds problems etc.)

Week 7

Shelter or dog pound? The past, the present and the future of „Illatos street”. Visiting in a dog shelter in Budapest

Week 10

ZOO versus animal protection. Visiting in the Budapest ZOO

Week 13

Saved wild animals (bears, wolves, raccoons). Visiting in Central Europe largest bear refuge, in the Bear Farm Veresegyház

19

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

BIOMATHS 2nd Semester Course description Course

Biomaths

Department

Department of Biomathematics and Informatics

Language

English

Nature

Mandatory

Year/semester

1st year, spring-term

Credits (ECTS)

3

Lectures (hour/semester)

15

Plenary lectures (hour/semester) Practicals (hour/semester)

30

Responsible teacher

Dr. Zsolt Lang

Teacher(s)

Dr. Andrea Harnos, Dr. Péter Fehérvári, Zsolt Abonyi Tóth, Mikolt Bakony, Dr. Szilvia Kövér, Dr. Nóra Vili

Prerequisites

Learning outcome (include skills and competencies, if any) Basic skills in statistical data analysis including the ability of collecting and suitably formatting data, carrying out simple exploratory and inferential statistical analyses, mastering the statistical software R Commander, and proper interpretation and reporting of the outcomes of the analyses.

Outcome assessment The final grade is based on the scores achieved on the final exam, on the two midterms, and on the weekly short tests in the practical sessions of the course.

Weekly schedule of lectures and practicals

20

WEEK

Lecture topics

Week 1

Introduction. Basic notions. Population and sample. Observational unit, variable.

Measurement scales. Descriptive statistics. Location and scale measures.

Week 2

Inductive statistics. Estimation and hypothesis tests. Popper’s theory of falsification.

Week 3

Probability theory. Random events.

Week 4

Probability theory. Random variables.

Week 5

Introduction to statistical hypothesis tests.

Week 6

Statistical hypothesis tests. Comparison of means. Comparison of variances. Parametric and nonparametric tests.

Week 7

Analysis of qualitative (nominal, ordinal) data. Chi-square goodness of fit test. Exact binomial test. Tests of independence and homogeneity: Pearson’s chi-square test, Fisher’s exact test.

Week 8

Correlation and regression analysis. Correlation coefficients. Testing hypotheses on correlation coefficients. Point and interval estimates of correlation coefficients. Regression models. Simple linear regression. Multiple linear regression. Testing hypotheses on regression models.

Week 9

Regression analysis, part II. Observations, estimations from the model, residuals.

Coefficient of determination. Regression diagnostics. Illustrative examples, applications.

SYLLABUS

WEEK

Lecture topics

Week 10

Application of probability theory in epidemiology. Prevalence, theorem of total probability.

Diagnostic tests. Sensitivity, specificity, positive and negative predictive value.

Week 11

Application of probability theory in epidemiology, part II. Comparison of diagnostic tests with the use of ROC curves. Comparison of diagnostic tests with the use of statistical tests.

Apparent and true prevalence. Rogan-Gladen formula.

Week 12

Analysis of variance (ANOVA). Analysis of covariance (ANCOVA). Methods of multiple comparison.

Week 13

Another example of two-way ANOVA. Design of experiments. Confounder variable, randomised block design.

Week 14

Logistic regression. Probability, odds, logit. What can we infer from the coefficients of the logistic regression? An illustrative application.

WEEK

Practical topics

Week 1

Introduction to the use of the R Commander software. Basic notions. Population and sample. Observational unit, variable. Measurement scales. Descriptive statistics. Location and scale measures.

Week 2

Introduction to the use of the R Commander software, part II.

Week 3

Calculation of probabilities of random events.

Week 4

Calculation and graphical presentation of the distributions of random variables with the use of R Commander.

Week 5

Application of t-tests, Mann-Whitney-Wilcoxon tests, sign tests, Wilcoxon’s signed rank tests, F tests, Levene tests, Mood’s median tests, Kruskal-Wallis tests. Point estimates, confidence intervals.

Week 6

Application of t-tests, Mann-Whitney-Wilcoxon tests, sign tests, Wilcoxon’s signed rank tests, F tests, Levene tests, Kruskal-Wallis tests. Point estimates, confidence intervals.

Week 7

1st midterm. Analysis of qualitative (nominal, ordinal) data. Chi-square goodness of fit test.

Exact binomial test.

Week 8

Analysis of qualitative (nominal, ordinal) data with the use of R Commander. Chi-square goodness of fit test. Exact binomial test. Median test, sign test. Tests of independence and homogeneity: Pearson’s chi-square test, Fisher’s exact test.

Week 9

Correlation and regression analysis with the use of R Commander. Correlation coefficients. Testing hypotheses on correlation coefficients. Point and interval estimates of correlation coefficients. Regression models. Simple linear regression. Multiple linear regression. Testing hypotheses on regression models.

Week 10

Correlation and regression analysis with the use of R Commander. Observations, estimations from the model, residuals. Coefficient of determination. Regression diagnostics. Illustrative examples, applications.

Week 11

Estimation of prevalence, sensitivity, specificity, positive and negative predictive value.

Comparison of diagnostic tests with the use of ROC curves. Comparison of diagnostic tests with the use of statistical tests. Estimation of apparent and true prevalence.

Week 12

Application of one-way analysis of variance (ANOVA) and multiple comparison methods.

Week 13

2nd midterm. Just another example of two-way ANOVA.

Week 14

Retake midterms. Mock final test with discussion.

Recommended literature Wassertheil-Smoller S: Biostatistics and Epidemiology. A Primer for Health and Biomedical Professionals, Springer, 1990, 1995, 2004. (It can be borrowed from the University Library.)

Petrie A, Watson P: Statistics for Veterinary and Animal Science. 3rd edition. Wiley-Blackwell, 2013.

21

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

BOTANY 2nd Semester Course description Course

Botany

Department

Department of Botany

Language

English

Nature

Mandatory

Year/semester

1st year, spring-term

Credits (ECTS)

6

Lectures (hour/semester)

30

Plenary lectures (hour/semester) Practicals (hour/semester)

45

Responsible teacher

Dr. Cserhalmi Dániel (Cserhalmi.Daniel@univet.hu)

Teacher(s)

Dr. Péli Evelin Ramóna, Kutszegi Gergely József

Prerequisites

Learning outcome (include skills and competencies, if any) During the semester students can learn about the most important crop and poisonous plant species, their general morphology, cytology and histology, as well as their metabolic processes resulting nutrients and secondary metabolites for animals. The fundamental role of plant primary metabolic processes in the biosphere is discussed and compared to bacterial, fungal, and animal metabolism. Paying extra attention to the health hazards caused by micro or macrofungi, or agricultural chemicals, the importance of food chain safety in veterinary medicine is highlighted.

The subject deals with grassland habitats also, as they are the main providers of animal forage.

Students will be able to recognise the most important crop, poisonous, medicinal and grasslands species. They will be also prepeared about their major nutritive value or poisonous/antinutritive/ medicinal effects on animals. However the course helps students to understand the synthesis and storage of plant metabolites. Students will be also able to perform stomach and hay analysis and evaluate hay quality. Students will be able to understand the role of bacterial and fungal species in heath hazards as well.

Outcome assessment During the semester students write three midterm test on the seminars where they need to identify species and also give their specific nutritives, antinutritives, and specific effects on animals. The rejection level is 50% for each tests. Each test must be passed to get the seminars accepted (receive signature) and get the possibility to take oral exam. For the oral exam students need to pick two questions: one covers the lectures and the other one is the seminars. Both topics must be passed for acceptance.

22

SYLLABUS

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Introduction, importance, nomenclature, and the basics of plant morphology

Week 2

Morphology of vegetative and generative organs of plants

Week 3

Plant cytology

Week 4

Plant histology

Week 5

Primary metabolism: comparison of bacterial, plant, fungal, and animal lifestyle

Week 6

Plant physiology: photosynthesis and ionic balance

Week 7

Secondary metabolites of plants 1.

Week 8

Secondary metabolites of plants 2.

Week 9

Plant taxonomy 1. (cryptogams and monocots)

Week 10

Plant taxonomy 2. (dicots)

Week 11

Grasslands of the world

Week 12

Microfungal health hazards: mycoses, mycotoxicoses

Week 13

Health hazards caused by macrofungi or agricultural chemicals

Week 14

Summary, consultation, discussion of exam topics

WEEK

Practical topics

Week 1

Cereals

Week 2

Pulse crops – oil plants

Week 3

Forage legumes – fleshy forages

Week 4

Plans producing cardiac glycosides or HCN, midterm test 1

Week 5

Plants promoting CNS symptoms

Week 6

Poisonous plants affecting the gastrointestinal tract, the respiratory system, more organ systems simultaneously or causing photosensitization

Week 7

Poisonous plants promoting cancer, producing oxalate crystals, accumulating nitrate ions, causing cytotoxicity, or affecting the clotting of blood

Week 8

Poisonous garden and indoor plants, midterm test 2

Week 9

Medicinal plants

Week 10

Grassland plants

Week 11

Botanical hay analysis in a horse stable, midterm test 3

Week 12

Visiting the botanical garden "Füvészkert"

Week 13

Botanical stomach content analysis

Week 14

Retake week

Recommended literature Lecture notes (files can be downloaded from the www.univet.hu website)

23

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

HISTOLOGY 2 2nd Semester Course description Course

Histology 2

Department

Department of Anatomy and Histology

Language

English

Nature

Mandatory

Year/semester

1st year, spring-term

Credits (ECTS)

5

Lectures (hour/semester)

30

Plenary lectures (hour/semester) Practicals (hour/semester)

45

Responsible teacher

Dr. Bence Rรกcz

Teacher(s)

Prof. Katalin Halasy, Dr. Bence Rรกcz

Prerequisites

Learning outcome (include skills and competencies, if any) On completion of Histology 2 students will have knowledge and understanding of the structural and functional organization of the various organs that can be found in domestic mamals and avian species. In addition, students should be able to relate cellular structure to complex tissue organization and function.

Outcome assessment End of Semester 1 hour MCQ written test. Practical exam to assess microscopy based laboratory skills. No midterms.

24

SYLLABUS

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

General Histology of Organs, Lymphatic organs

Week 2

Digestive system I.

Week 3

Digestive system II.

Week 4

Digestive system III.

Week 5

Respiratory organs

Week 6

Urinary Organs

Week 7

Male genital organs

Week 8

Female genital organs

Week 9

Endocrine organs

Week 10

Central nervous system

Week 11

Sensory organs I.

Week 12

Sensory organs II.

Week 13

Outer integument (skin) & Mammary gland

Week 14

Avian histology

WEEK

Practical topics

Week 1

Lymphatic organs

Week 2

Digestive system I.

Week 3

Digestive system II.

Week 4

Digestive system III.

Week 5

Digestive system IV.

Week 6

Respiratory organs

Week 7

Urinary Organs

Week 8

Male genital organs

Week 9

Female genital organs

Week 10

Endocrine organs

Week 11

Central nervous system

Week 12

Visual organ

Week 13

Outer integument (skin) & Mammary gland

Week 14

Avian histology

Recommended literature Dellmann: Textbook of veterinary histology

Note(s) At certain points in the course it may make good sense to modify the schedule outlined above.

Teachers reserve the right to modify elements of the course and will notify students accordingly.

25

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

VETERINARY- AND FOOD CHEMISTRY 2nd Semester Course description Course

Veterinary- and food chemistry

Department Language

English

Nature

Mandatory

Year/semester

1st year, spring-term

Credits (ECTS)

5

Lectures (hour/semester)

45

Plenary lectures (hour/semester) Practicals (hour/semester)

30

Responsible teacher

dr. Zoltรกn Vincze

Teacher(s)

Dr. Zoltรกn Vincze, Dr. Tamรกs R. Varga, Dr. Mihรกly V. Pilipecz, Anna Alekszi-Kaszรกs

Prerequisites

Outcome assessment At the end of the semester the students have to pass an oral examination, which comprises the subjects of lectures and laboratory exercises of Semester II. Before beginning the examination all students have to fill a placement quiz (10 fundamental structural formulas). Students who have less than 5/10 result are not permitted to continue exam and its grade (failed) will be introduced in the lecture book.

However, passing a placement quiz does not mean passing the exam. Every student has to answer orally two topics from different parts of organic chemistry and one topic from food chemistry and has got 30 minutes to meditate on that (it is advisable to make a short sketch about them).

26

SYLLABUS

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Aliphatic and aromatic hydrocarbons.

Week 2

Alkyl halides, Aryl halides. Aliphatic alcohols.

Week 3

Phenols, aromatic alcohols, quinones. Ethers. Aliphatic amines.

Week 4

Aromatic amines and other N-comp. Aliphatic and aromatic carbonyl comp.

Week 5

Carboxylic acids and derivatives. Carbonic acid derivatives. Stereoisomerism.

Week 6

Steroids, terpenes, carotenoids, heterocycles, alkaloids.

Week 7

Nucleic acids. Carbohydrates.

Week 8

Amino acids, peptids, proteins.

Week 9

Biomaterials in medicine.

Week 10

Food Additives: Thickening Agents, Gel Builders, Stabilizers.

Week 11

Food Additives: Preservatives, Antioxidants.

Week 12

Chemistry of Color Food Colors.

Week 13

Aroma Substances, Flavor Enhancers, Sweeteners.

Week 14

Analytical Methods in Food Chemistry. Food Contamination.

WEEK

Practical topics

Week 1

Titration: Acidi-Alkalimetry (wine), Complexometry (milk).

Week 2

Potentiometric titration (cola)

Week 3

Organic Chemistry Practice 1

Week 4

Organic Chemistry Practice 2

Week 5

Organic Chemistry Practice 3

Week 6

Seminar I.

Week 7

Organic Chemistry Practice 4

Week 8

Organic Chemistry Practice 5

Week 9

Organic Chemistry Practice 6

Week 10

Organic Chemistry Practice 7

Week 11

Chromatography

Week 12

Seminar II.

Week 13

Isolation of Caffeine

Week 14

Make-up labs

Recommended literature R. C. Atkins, F. A. Carey: ORGANIC CHEMISTRY, International Edition (McGraw-Hill Publishing, Company, 1990, ISBN 0-07-100667-2) H.-D. Belitz, W. Grosch, P. Schieberle: FOOD CHEMISTRY, 4th Edition (Springer-Verlag Berlin Heidelberg 2009, ISBN 978-3-540-69933-0)

27

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

3RD SEMESTER

28

SYLLABUS

AGROECONOMICS 3rd Semester Course description Course Department Language Nature Year/semester Credits (ECTS) Lectures (hour/semester) Plenary lectures (hour/semester) Practicals (hour/semester) Responsible teacher Teacher(s) Prerequisites

Agroeconomics Department of Veterinary Forensics and Economics English Mandatory 2nd year, winter-term 3 30 30 0 Dr. László Ózsvári Dr. László Ózsvári, Dr. István Fodor

Learning outcome (include skills and competencies, if any) Understanding the basic principles of economics and agricultural economics with special regard to the agricultural markets in action. Gaining knowledge of the global and European agricultural production with special regard to the food of animal origin.

Outcome assessment Written exam Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1 Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8 Week 9 Week 10 Week 11 Week 12 Week 13 Week 14

General introduction.

Introducing the economic way of thinking. Resources Production possibilities, opportunity cost, economic growth Agricultural market demand and supply Agricultural markets in action. Consumer choice theory Price elasticity of demand and supply Agricultural yield and production costs Farm budget and business analysis Main economic aspects of milk production and the beef sector Main economic aspects of forage crops and the swine sector Main economic aspects of the sheep and goat sector Main economic aspects of the poultry sector Main economic aspects of the aquaculture production Economic aspects of food of animal origin

Recommended literature Penson, J. – Capps, O. – Rosson, C. – Woodward, R.: Introduction to Agricultural Economics, Global, Edition, 6th Edition, Pearson, 2015, 432 p., Tucker, I.: Economics for Today. Thomson-South-Western, 2005.

29

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

ANATOMY 3 3rd Semester Course description Course

Anatomy 3

Department Language

English

Nature

Mandatory

Year/semester

2nd year, winter-term

Credits (ECTS)

7

Lectures (hour/semester)

30

Plenary lectures (hour/semester) Practicals (hour/semester)

45

Responsible teacher

Prof. Dr. Sótonyi Péter

Teacher(s)

Dr. Szalay Ferenc, Dr. Heinzlmann Andrea, Dr. Hazai Diana, Dr. Reinitz László, Dr. Kondor Milán

Prerequisites

Learning outcome (include skills and competencies, if any) The gross anatomy of the nervous system and sensory organs of domestic mammals are delt with; preparation for the final dissection.

Outcome assessment Final dissection exam on fresh canine cadavers, topics covering all 3 semesters.

Final theoretical exam: written entrance exam (single choice question, passing grade: 60%) + oral exam on 6 topics covering all 3 semesters, including anatomy of domestic birds and embriology.

30

SYLLABUS

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Week 14

Lymphatic system The neuron principle: morphological basis of neural function. The development of the nervous system Brachial plexus Lumbosacral plexus Cranial nerves Cranial nerves Cranial nerves Cranial nerves Autonomous nervous system Autonomous nervous system Brain Brain Tracts and blood supply of the spinal cord, Meninges and blood supply of the CNS, Visual organ/circulation of the CSF Hoof, mammary gland

WEEK

Practical topics

Week 1 Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8 Week 9 Week 10 Week 11 Week 12 Week 13 Week 14

Semester Information Lymphatic system Brachial plexus Lumbosacral plexus Cranial nerves Cranial nerves Cranial nerves Cranial nerves Autonomous nervous system Dissection of final topics I. Dissection of final topics II. Brain Dissection of final topics III. Dissection of final topics IV.

Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8 Week 9 Week 10 Week 11 Week 12 Week 13

Recommended literature König-Liebich: Veterinary Anatomy of Domestic Mammals: Textbook and Colour Atlas; Nickel, Schummer, Seiferle: Anatomy of the Domestic Animals; Dyce, Sack, Wensing: Textbook of veterinary anatomy; Constantinescu: Illustrated Veterinary Anatomical Nomenclature; EvansdeLahunta: Miller’s Anatomy of the Dog; Evans-deLahunta: Guide to the dissection of the Dog; Sótonyi Péter: Anatomia Canis CD-ROM; Budras: Anatomy of the Dog, An Illustrated Text; Budras: Anatomy of the Horse;

Note(s) Exam topic list is downloadable from the website of the Department.

31

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

ANIMAL BREEDING 3rd Semester Course description Course

Animal breeding

Department

Department for Animal Breeding, Nutrition and Laboratory animal science

Language

English

Nature

Mandatory

Year/semester

2nd year, spring-term

Credits (ECTS)

3

Lectures (hour/semester)

30

Plenary lectures (hour/semester) 30 Practicals (hour/semester) Responsible teacher

Dr. András Gáspárdy

Teacher(s)

Dr. András Gáspárdy, Dr. László Zöldág, Dr. Ákos Maróti-Agóts, Dr. Boglárka Vincze, Dr. Petra Zenke, Dr. Zsolt Szmodits

Prerequisites

Learning outcome (include skills and competencies, if any) This subject, putting a special emphasis on Mendelian, immuno-, clinical (hereditary diseases), population and molecular genetics, furthermore biotechnology and preservation of genetic resources. The methods of breeding value evaluation, selection, breeding improvement, and breeding systems are also synthesized, using the classical and up to date scientific knowledge of Mendelian, population and molecular genetics

Outcome assessment There are fluent repeatation and knowledge control of the actual topics lecture by lecture on the course of the semester. A mid-term test is kept for strengthening of basic learning in October.

In the regular exam period, the exam consists of two (practical and theoretical) parts. At first, students are controlled by a questionnaire on computer (according to their rapid answers to basic figures, definitions, associations and calculations) as a threshold to enter into the theoretical part. The performance from 60% is successful. And then, they choose four questions, and after a preparation time they answer these orally. All the four questions should be answered (a single unknown question leads to failure). All questions are published in advance. In case of failed exam, students with at least 80% performance in computer test do not need to repeat the practical part.

Time span between the exam failed and its re-take should exceed 5 days.

32

SYLLABUS

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Introduction. Domestication of species, evolutionary consequences

Week 2

Fundamentals of Mendelian, cyto- and molecular genetics, pediatric genetics

Week 3

Mendelian exceptions (expressivity, penetrance, allelic polymorphism, recombination immunogenetics, lethal genes, pleiotropy epigenetics)

Week 4

Clinical genetics, hereditary abnormalities (mono/oligogenic, mutations, diagnosis, prevention, liability) and epigenetics

Week 5

Mendelian exceptions (linkage, sex linked, XL, ZL, uniparental inheritance and monogenes, major genes, epistasis)

Week 6

Biotechnology in animal breeding (cloning, GMO, transgenesis, genome editing)

Week 7

Biotechnology in animal breeding (AI, ET, MOET, EMT)

Week 8

Qualitative population genetics: polymorphism, gene and genotype frequencies, haplotype

Week 9

Quantitative population genetics: heritability, repeatability, correlation, regression

Week 10

Valuable traits, terms of breeding value and its estimation

Week 11

Selection (methods, types, forms, selection index, MAS, efficiency)

Week 12

Mating methods and breeding systems: pure breeding, crossbreeding, heterosis

Week 13

Preservation and conservation of genetic diversity and resources, endangered breeds

Week 14

Animal production technology. Concept of type, basics of conformation judging

WEEK

Practical topics

Week 1

Life career, lifetime and age estimation

Week 2

Individual markings, herd booking, identification, traceability

Week 3

Taking biological samples, parentage and identity control, DNA-polymorphisms (microsatellites, SNP)

Week 4

Molecular diagnosis of hereditary disorders

Week 5

Autosomal and X-linked inheritance in practical animal breeding

Week 6

Practical biotechnology: artificial insemination (AI) and embryo transfer (MOET)

Week 7

Practical biotechnology: embryo manipulations (EMT) and cloning

Week 8

Transgenesis, gene editing, gene-mapping, QTL analysis, application of genomial information

Week 9

Calculation of gene and genotype frequencies

Week 10

Bioinformatics

Week 11

Calculation of breeding value

Week 12

Calculation of genetic improvement (response to selection)

Week 13

Pedigree analysis, calculation of genetic relationship and inbreeding coefficients

Week 14

Taking body measurements on living animal and pictures (VAM), geometric morphometry

Recommended literature Zöldág, L. - Gáspárdy, A. – Maróti-Agóts, Á. – Buleca, J. – Seregi, J. – Matiuti, M. (2008): Veterinary genetics and animal breeding (ed. Zöldág László). A/3 Printing Ltd., Budapest, ISBN 978-96388110-0-4.; Introduction to veterinary genetics 3rd ed. Nicholas, Wiley-B. 2009; Molecular and Quantitative Animal Genetics Hasan Khatib, Wiley-B. 2015 33

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

VETERINARY BIOCHEMISTRY 1 3rd Semester Course description Course

Veterinary biochemistry 1

Department

Division of Biochemistry, Department of Physiology and Biochemistry

Language Nature Year/semester Credits (ECTS) Lectures (hour/semester) Plenary lectures (hour/semester) Practicals (hour/semester) Responsible teacher

English Mandatory 2nd year, winter-term 5 45

Teacher(s)

Dr. Gábor Mátis, DVM, PhD; Dr. Máté Mackei, DVM; Dr. Kata Orbán, DVM

15 Dr. Zsuzsanna Neogrády, DVM, CSc

Prerequisites

Learning outcome (include skills and competencies, if any) On completion of Veterinary biochemistry 1 students should be able to explain and describe: - How the stable internal environment of the animal body is maintained?

- How the chemical processes, facilitated and regulated by specialized proteins called enzymes, supporting living organism?

- How the chemical exchange between two different parts of a cell, or the inside of a cell and its external environment is controlled?

- Which interrelationships between the structure and function of the most important biological macromolecules exist?

- How the nucleic acids DNA and RNA differ in composition and structure and how they can be synthetized and broken down in the living cells?

- Which fundamental concepts and steps of molecular biology and genetic engineering exist?

Outcome assessment The prevalent qualification system and requirements in subject “Veterinary Biochemistry 1.” are as follows: Regular visiting of the lectures (no more than 3 unjustified absences can be accepted) Successful performance of all laboratory practicals Completion of 60% of the maximal scores in the laboratory practicals Completion of 60% of the maximal scores on the written midterm test Weekly schedule of lectures and practicals

34

WEEK

Lecture topics

Week 1

Introduction. Internal environment, homeostasis. Isovolaemia, isotonia, isoionia.

Isohydria, buffer systems. Structure of the biological membranes.

Week 2

Transport across the biological membranes. Classification and structure of the proteinogenic amino acids. The peptide bond.

Week 3

General characterization and structure of proteins. Denaturation and renaturation of proteins. Classification of proteins. Structural proteins: collagen, elastin, keratin.

Week 4

Characterization of enzymes. Mechanism of enzyme action. Reversibility of enzymatic reactions. Factors influencing the velocity of enzymatic reactions. The regulation of the enzyme activity. The inhibition of the enzyme activity. Nomenclature, classification and cellular localization of enzymes.

SYLLABUS

WEEK

Lecture topics

Week 5

Structure of nucleotides. De novo synthesis and degradation of purine nucleotides.

Week 6

De novo synthesis and degradation of pyrimidine nucleotides. Salvage pathways of nucleotide metabolism (resynthesis of nucleotides). Metabolism of deoxyribonucleotides. The structure and function of DNA.

Week 7

Replication of DNA in prokaryotes and eukaryotes. Mutations, repair mechanisms.

The structure of the transcription unit in prokaryotes and eukaryotes. Transcription and its regulation in prokaryotes.

Week 8

Transcription and its regulation in eukaryotes: gene expression, epigenetic regulatory mechanisms. Structure of the ribosomes. Activation of the amino acids. The steps of the translation in eukaryotes.

Week 9

The steps of the translation in prokaryotes. The regulation and energy balance of the translation. Posttranslational modifications of proteins. Recombinant DNA technology and biotechnology.

Week 10

General introduction to the intermediary metabolism. Biological oxidation.

Conservation of metabolic energy in the cell: high energy phosphates. Metabolism of creatine. Chemistry of carbohydrates: role, classification: monosaccharides, oligosaccharides, homo- and heteropolysaccharides. Cori cycle.

Week 11

Glycogen metabolism: glycogenolysis and glycogenesis. The glucagon and insulin signalling pathways. Glycolysis and gluconeogenesis: steps.

Week 12

Glycolysis and gluconeogenesis: regulation. Glycerol phosphate shuttle. Pasteur effect. The oxidation of pyruvate to acetyl CoA. The citric acid cycle.

Week 13

The respiratory chain and the oxidative phosphorylation. The pentose phosphate pathway.

Week 14

Blood sugar level and its regulation. Metabolism of fructose and galactose.

WEEK

Practical topics

Week 3

1. Examination of some biochemical parameters of the blood plasma

Week 5

2. Examination of proteins

Week 8

3. General properties of the enzyme activity

Week 10

4. Examination of the enzymes of digestion

Week 12

5. Examination of nucleic acids

Recommended literature 1. Your own Lecture Notes written during the lectures 2. Downloads (Homepage of the Department of Physiology and Biochemistry): Lecture Notes by Susan Neogrady • Biochemistry, Laboratory Manual: Downloads: Homepage of the Department of Physiology and Biochemistry 3. Recommended readings • Lehninger Principles of Biochemistry by D.L. Nelson and M.M. Cox, 2017 • BRS Biochemistry, Molecular Biology, and Genetics (Board Review Series) Seventh Edition by Lieberman, Michael A. and Ricer, Rick, 2019 • Biochemistry, International Version by Jeremy M. Berg, John L. Tymoczko, and Lubert Stryer, 2011 • Clinical Biochemistry of Domestic Animals by Jiro Kaneko John Harvey Michael Bruss, 2008

Note(s) For students exempted from Biochemistry 1. is necesarry to attend the lectures of week 10-14 of the first semester

35

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

VETERINARY PHYSIOLOGY 1 3rd Semester Course description Course

Veterinary physiology 1

Department Language

English

Nature

Mandatory

Year/semester

2nd year, winter-term

Credits (ECTS)

6

Lectures (hour/semester)

45

Plenary lectures (hour/semester) Practicals (hour/semester)

15

Responsible teacher

Tibor Bartha

Teacher(s)

Tibor Bartha, Laszlo V. Frenyo, David S. Kiss, Istvan Toth, Gergely Jocsak, Zoltan Barany, Timea Makk

Prerequisites

Learning outcome (include skills and competencies, if any) Veterinary physiolgy deals with the underlying physiological principles of veterinary medicine, veterinary practice and it also gives an insight into research activities of the field.

By completing Physiology 1, student should be able to describe physiologyical processes and regulatory mechanisms in the following topics: Homeostasis, Immunology, Muscle function, Cardiovascular system, Kidney physiology, Respiration and Energy balance.

Teaching and learning strategies: lectures, laboratory based practicals sessions, self-directed learning.

During the Physiology practical courses our aim is to prepare students for the manual work that is an essential part of the veterinary practice.

Outcome assessment At the end of physiology 1, students receive a grade based on their points collected in the semester (mid-term tests and on the labs).

The semeter is accapted above 50% if student has no failed or missed midterm or labs.

Top 10% of the class receives �excellent� grade.

36

SYLLABUS

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Introduction

Week 2

Inner environment, blood

Week 3

Inner environment, blood

Week 4

Immuno-physiology

Week 5

Muscle physiology First midterm test

Week 6

Muscle physiology Cardiovascular system

Week 7

Cardiovascular system

Week 8

Cardiovascular system

Week 9

Kidney physiology Second midterm test

Week 10

Kidney physiology

Week 11

Kidney physiology

Week 12

Respiration Third midterm test

Week 13

Respiration Energy metabolism

Week 14

Make up midterms Heat regulation

WEEK

Practical topics

Week 3

Hematology 1

Week 4

Hematology 1

Week 5

Hematology 2

Week 6

Hematology 2

Week 8

Muscle physiology

Week 9

Muscle physiology

Week 10

Heart and circulation

Week 11

Heart and circulation

Week 12

Respiration, Excretion

Week 13

Respiration, Excretion

Week 14

Make-up labs

Recommended literature Lecture and lab notes available in pdf format.

Cunnigham J. G. (2007): Textbook of Veterinary Physiology. hiladelphia: W. B. Saunders Sjaastad O. V., Hove K., Sand O. (2010): Physiology of Domestic Animals. Oslo: Scandinavian Veterinary Press Swenson M. J. (2004): Dukes’ Physiology of Domestic Animals. Ithaca, London: Cornell University Press

37

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

VETERINARY PROFESSION 3rd Semester Course description Course

Veterinary profession

Department Language

English

Nature

Mandatory

Year/semester

2nd year, winter-term

Credits (ECTS)

1

Lectures (hour/semester)

15

Plenary lectures (hour/semester) Practicals (hour/semester)

0

Responsible teacher

Prof. Sr. Sótonyi Péter

Teacher(s)

Prof. Dr. Abonyi Tamás, Dr. Krajcsovics László, Dr. Pintér Zsolt; Dr. Búza László, Dr. Süth Miklós, Prof.

Dr. Horn Péter

Prerequisites

Learning outcome (include skills and competencies, if any) Students get the opportunity to meet with professionals of every field.

Outcome assessment Written exam with single answer questions, covering every lectured topic. Passing grade: 50% Weekly schedule of lectures and practicals

WEEK Week 1 Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8 Week 9 Week 10 Week 11 Week 12 Week 13 Week 14 38

Lecture topics Prof. Dr. Abonyi Tamás introduces the NÉBIH and the food-chain system.

Dr. Süth Miklós introduces the official veterinary service.

Dr. Krajcsovics László talks about the job of a veterinarian on swine farm and in a mixed praxis Dr. Pintér Zsolt introduces the Federation of Veterinarians of Europe Dr. Búza László introduces the Veterinary Chamber system and the professional insurance system Prof. Dr. Horn Péter talks about the role of the veterinarian in a animal breeding and the general situation of the agriculture.

EXAM

SYLLABUS

4TH SEMESTER

39

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

ANIMAL BREEDING 4th Semester Course description Course

Animal breeding

Department

Department for Animal Breeding, Nutrition and Laboratory animal science

Language

English

Nature

Mandatory

Year/semester

2nd year, spring-term

Credits (ECTS)

6

Lectures (hour/semester)

45

Plenary lectures (hour/semester) 30 Practicals (hour/semester) Responsible teacher

Dr. András Gáspárdy

Teacher(s)

Dr. András Gáspárdy, Dr. László Zöldág, Dr. Ákos Maróti-Agóts, Dr. Boglárka Vincze, Dr. Petra Zenke, Dr. Zsolt Szmodits

Prerequisites

Learning outcome (include skills and competencies, if any) Husbandry guidelines for farm livestock, major hen species and pet (dog and cat) animals.

An introduction to the characterization and utilization of main domestic animal species.

To develop a basic understanding of specific purpose of animals under given cultural, economical and geographical condition.

Outcome assessment There are fluent repeatation and knowledge control of the actual topics lecture by lecture on the course of the semester. A mid-term test is kept for strengthening of basic learning in October.

In the regular exam period, the exam consists of two (practical and theoretical) parts. At first, students are controlled by a questionnaire on computer (according to their rapid answers to basic figures, breeds, tools, wool samples and age determination) as a threshold to enter into the theoretical part. The performance from 60% is successful. And then, they choose four questions, and after a preparation time they answer these orally. All the four questions should be answered (a single unknown question leads to failure). All questions are published in advance. In case of failed exam, students with at least 80% performance in computer test do not need to repeat the practical part. Time span between the exam failed and its re-take should exceed 5 days.

40

SYLLABUS

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Horse breeding introduction, evolution, domestication (2h) Use of horses (1h) Horse breeds (warm blooded, cold blooded, ponies, types) and donkey, horse breeding methods (2h) Horse colour inheritance and genotyping (1h)

Week 2

Week 9 Week 10 Week 11 Week 12 Week 13 Week 14

Horse reproduction, genetic diseases (2h) Horse important traits, breeding value estimation (1h) Cattle breeding introduction, Dairy traits (2h) Dairy traits continued (1h) Breeding value estimation of dairy cattle (2h) Breeding value estimation of beef cattle (1h) Beef cattle traits (2h) Methods of cattle breeding (1h) Sheep and goat introduction (2h) Sheep and goat traits (1h) Cattle, sheep and goat reproduction, and genetic diseases (2h) Sheep and goat breeds, breeding methods breeds (1h) Pig introduction (2h) Pig traits and breeding value estimation (1h) Pig breeds and breeding methods (2h) Pig reproduction and genetic diseases (1h) Dog breeding (2h) Dog reproduction and genetic diseases (1h) Cat breeding (2h) Cat reproduction and genetic diseases (1h) Hen breeding (broiler production) (2h) Hen breeding (egg production) (1h) Ducks and goose breeding (2h) Turkey and pigeon breeding (1h)

WEEK

Practical topics

Week 1 Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8 Week 9 Week 10 Week 11 Week 12 Week 13

Horse age determination Horse breeding, foal’s raising, keeping conditions Dairy cattle breeds and their recognition Dairy cattle technology, milk production and hygiene Beef and dual purpose cattle breeds and their recognition Beef cattle technology Sheep and goat technology (breeds used) Wool classification and evaluation Pig breeds and their recognition Pig technology Dog breeds and their recognition Cat breeds and their recognition Hen technologies, breeds, hybrids and their recognition Water poultry, turkey and pigeon technologies, species, breeds, hybrids and their recognition

Week 3 Week 4 Week 5 Week 6 Week 7 Week 8

Week 14

Recommended literature Zöldág, L. - Gáspárdy, A. – Maróti-Agóts, Á. – Buleca, J. – Seregi, J. – Matiuti, M. (2008): Veterinary genetics and animal breeding (ed. Zöldág László). A/3 Printing Ltd., Budapest, ISBN 978-963-88110-0-4. Understanding Animal Breeding. Richard M. Bourdon. Second Edition, 2014. Pearson ISBN 10: 1-292-04003-3

Note(s) A subsequent summer farm practical is compulsory. A summer report, as well as a diary describing the daily activities shall be prepared and handed in by the beginning of the actual semester. Submission of them is a prerequisite for attendance of the subject and for exam on it.

41

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

TOPOGRAPHIC AND APPLIED ANATOMY 4th Semester Course description Course

Topographic and applied anatomy

Department Language

English

Nature

Mandatory

Year/semester

2nd year, spring-term

Credits (ECTS)

4

Lectures (hour/semester)

15

Plenary lectures (hour/semester) Practicals (hour/semester)

30

Responsible teacher

Prof. Dr. Sótonyi Péter

Teacher(s)

Dr. Szalay Ferenc, Dr. Hazai Diana, Dr. Reinitz László, Dr. Kapiller Mátyás, Dr. Kondor Milán

Prerequisites

Learning outcome (include skills and competencies, if any) Topographic and applied anatomy provides the connection of functional anatomy and further clinical studies. After dissection labs of Anatomy 1 -3 topographic anatomy labs enlight palpation, nerve block, auscultation etc. technics.

Outcome assessment The practical exam is a prerequisite to the theory part. It involves identification of 40 features accessible on a live horse, 40 features accessible on a live dog or a canine carcasses (here including invasive techniques, too).

Theoretical exam is a written test with simple choice, figure labelling and short answers.

Pass level is 60%

42

SYLLABUS

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Clinical anatomy of the canine forelimb

Week 2

Clinical anatomy of the canine hindlimb

Week 3

Clinical anatomy of the canine head

Week 4

Clinical anatomy of the canine neck

Week 5

Clinical anatomy of the canine thorax

Week 6

Clinical anatomy of the canine pelvis

Week 7

Clinical anatomy of the canine abdomen

Week 8

Clinical anatomy of the equine forelimb

Week 9

Clinical anatomy of the equine hindlimb

Week 10

Clinical anatomy of the equine head

Week 11

Clinical anatomy of the equine thorax

Week 12

Clinical anatomy of the equine abdomen

Week 13

Clinical anatomy of the equine pelvis

Week 14

Consultation

WEEK

Practical topics

Week 1

Clinical anatomy of the canine forelimb

Week 2

Clinical anatomy of the canine hindlimb

Week 3

Clinical anatomy of the canine head

Week 4

Clinical anatomy of the canine neck

Week 5

Clinical anatomy of the canine thorax

Week 6

Clinical anatomy of the canine pelvis

Week 7

Clinical anatomy of the canine abdomen

Week 8

Clinical anatomy of the equine forelimb

Week 9

Clinical anatomy of the equine hindlimb

Week 10

Clinical anatomy of the equine head

Week 11

Clinical anatomy of the equine thorax

Week 12

Clinical anatomy of the equine abdomen

Week 13

Clinical anatomy of the equine pelvis

Week 14

Consultation

Recommended literature de La Hunta and Habel: Applied Veterinary Anatomy

43

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

VETERINARY BIOCHEMISTRY 2 4th Semester Course description Course

Veterinary biochemistry 2

Department

Division of Biochemistry, Department of Physiology and Biochemistry

Language

English

Nature

Mandatory

Year/semester

2nd year, spring-term

Credits (ECTS)

6

Lectures (hour/semester)

45

Plenary lectures (hour/semester) Practicals (hour/semester)

15

Responsible teacher

Dr. Zsuzsanna Neogrády, DVM, CSc

Teacher(s)

Dr. Gábor Mátis, DVM, PhD; Dr. Máté Mackei, DVM; Dr. Kata Orbán, DVM

Prerequisites

Learning outcome (include skills and competencies, if any) On completion of Veterinary biochemistry 2. students should be able to explain and describe: - How macromolecules (carbohydrates, lipids, proteins and nucleic acids) will be broken down in the animal cells in order to provide energy or building blocks for biosynthetic pathways?

Understanding of enzymatic reactions such as glycogenolysis, glycolysis, lipolysis, fatty acid oxidation, nucleotide and amino acid metabolism is highlighted also.

- How ATP and other high-energy bond containing molecules can be produced in the biological oxidation during the course of catabolic enzymatic reactions related to the citrate cycle and oxidative phosphorylation?

- How macromolecules will be synthetised in the course of glycogenesis, gluconeogenesis, fatty acid and nucleic acid synthesis, further in different reactions of amino acid and protein metabolism?

- Which differences exist between the intermediary metabolism of ruminants and non-ruminant mammals?

- How to characterize the intermediary metabolism of different organs in animal body?

- How vitamins as cofactors of the catabolic and anabolic reactions are able to influence the intermediary metabolism of macromolecules: the biochemical reasons and consequences of vitamin deficiency in animals.

The course gives not only an overview of basic biochemical pathways, but concentrates on clinical aspects of the subject including conditions and cases where biochemistry is used in diagnosis and treatment of different illnesses?

44

SYLLABUS

Outcome assessment The prevalent qualification system and requirements in subject “Veterinary Biochemistry 2.” are as follows: Regular visiting of the lectures (no more than 3 unjustified absences can be accepted).

Successful performance of all laboratory courses.

Taking part on all plenary practicals.

Completion of 60% (15 points) of the maximal scores (25 points) in the laboratory courses.

Completion of 60% (18 points) of the maximal scores (30 points) on the written midterm test or midterm retake. If midterm retake is failed, the semester can be accepted if the student gets an “accepted” grade for the oral or written examination at the end of the semester.

Studying Veterinary Biochemistry ends with final examination. The grade of the final exam on Veterinary Biochemisty will be evaluated based on four partial grades as follows: Practical course grade: determined based on the sum of the points completed on the five practicals and the midterm test of Veterinary Biochemistry 2.

Grade of the written part of the exam. Oral exam: grades given for the two topics.

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Amino acid metabolism: transamination, oxidative deamination. Glucogenic, ketogenic, essential, non-essential amino acids.

Week 2

Detoxification of ammonia: urea cycle, ammonium ion formation. Decarboxylation of amino acids, most important peptides.

Week 3

Structure of heme. Porphyrine metabolism: synthesis and degradation. Hemoglobin, Myoglobin, Catalase, Peroxidase, Cytochromes. Iron metabolism. Role and chemical structure of lipids. Absorption and transport of lipids.

Week 4

Lipolysis, degradation of fatty acids: beta-oxidation (even-, odd-carbon and unsaturated fatty acids). Degradation of glycerol, biosynthesis of oxaloacetate, ketogenesis, ketolysis.

Week 5

Synthesis of fatty acids: even-carbon, odd-carbon, unsaturated fatty acids. Synthesis of glycerol. Biosynthesis of fats (lipids). Lipoids: phosphoglycerides, sphingolipids, steroids: cholesterol, bile acids. Carotenoids.

Week 6

Role of the liver: intermediary metabolism, secretion, detoxification: synthesis, oxidation, reduction, hydrolysis, conjugation.

Week 7

Biochemistry of muscle (striated, red, white and cardiac muscle), muscle proteins, muscle contraction. Biochemistry of brain and adipose tissue.

Week 8

Carbohydrate metabolism of ruminants: Production and absorption of volatile fatty acids. Metabolism of the volatile fatty acids in the ruminants’ tissues.

Week 9

Metabolism of nitrogen-containing compounds in ruminants. Lipid metabolism of ruminants. Ketosis of the ruminants. Biochemistry of milk production.

Week 10

Introduction of vitamins. Biochemistry of retinol (vitamin A) and calcipherol (vitamin D).

Week 11

Biochemistry of tocopherol (vitamin E), phylloquinon (vitamin K), essential fatty acids and thiamine (vitamin B1).

Week 12

Biochemistry of riboflavin (vitamin B2), niacinamide (vitamin B3), pantothenic acid (vitamin B5) and pyridoxine (vitamin B6).

Week 13

Biochemistry of biotin (vitamin B7), folic acid (vitamin B9) and cobalamin (vitamin B12).

Week 14

Biochemistry of ascorbic acid (vitamin C) and lipotropic factors (choline, inositol).

45

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

WEEK Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8 Week 9 Week 10 Week 11

Practical topics Digestive system I. Digestive system III. Respiratory organs Male genital organs Endocrine organs

Recommended literature 1. Your own Lecture Notes written during the lectures 2. Downloads (Homepage of the Department of Physiology and Biochemistry): Lecture Notes by Susan Neogrady • Biochemistry, Laboratory Manual: Downloads: Homepage of the Department of Physiology and Biochemistry 3. Recommended readings • Lehninger Principles of Biochemistry by D.L. Nelson and M.M. Cox, 2017 • BRS Biochemistry, Molecular Biology, and Genetics (Board Review Series) Seventh Edition by Lieberman, Michael A. and Ricer, Rick, 2019 • Biochemistry, International Version

by Jeremy M. Berg, John L. Tymoczko, and Lubert Stryer, 2011 • Clinical Biochemistry of Domestic Animals by Jiro Kaneko John Harvey Michael Bruss, 2008

Note(s) At certain points in the course it may make good sense to modify the schedule outlined above.

Teachers reserve the right to modify elements of the course and will notify students accordingly.

46

SYLLABUS

VETERINARY PHYSIOLOGY 2 4th Semester Course description Course

Veterinary physiology 2

Department Language

English

Nature

Mandatory

Year/semester

2nd year, spring-term

Credits (ECTS)

7

Lectures (hour/semester)

60

Plenary lectures (hour/semester) Practicals (hour/semester)

15

Responsible teacher

Tibor Bartha

Teacher(s)

Tibor Bartha, Laszlo V. Frenyo, David S. Kiss, Istvan Toth, Gergely Jocsak, Zoltan Barany, Timea Makk

Prerequisites

Learning outcome (include skills and competencies, if any) Veterinary physiology deals with the underlying physiological principles of veterinary medicine, veterinary practice and it also gives an insight into research activities of the field.

By completing Physiology 2, student should be able to describe physiological processes and regulatory mechanisms in the following topics: Digestion of domestic animals, Endocrinology, Animal reproduction, Neurophysiology and Bone physiology.

Teaching and learning strategies: lectures, laboratory based practicals sessions, self-directed learning.

During the Physiology practical courses our aim is to prepare students for the manual work that is an essential part of the veterinary practice.

Outcome assessment Final exam of all topic from Physiology 1 and 2 Written exam that consists of three parts and should be completed within 100 minutes.

1. Multiple-choice test: to check factual knowledge of the most relevant topics 2. Figure analysis: to check general understanding of physiological processese. Student interprets figures by completing the figure and answering related questions.

3. Two essays (unrelated to the chapter covered by the figure): to check the comprehnesive knowledge of a larger topic of physiology.

For passing the exam, a student has to reach at more than 33 % on the multiple choice test, more 25 % on the figure and the essays, and should collect more than 50% in total.

47

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Digestion and absorption

Week 2

Digestion and absorption

Week 3

Digestion and absorption Endocrinology

Week 4

Fourth Midterm Test Endocrinology

Week 5

Endocrinology

Week 6

Endocrinology Nervous system

Week 7

Fifth Midterm Test Nervous system

Week 8

Nervous system

Week 9

Nervous system

Week 10

Sixth Midterm Test Reproduction

Week 11

Reproduction

Week 12

Reproduction

Week 13

Bone and minerals

Week 14

Make-up Midterms Bone and minerals

WEEK

Practical topics

Week 2

Cardiovascular regulation

Week 3

Cardiovascular regulation

Week 4

Digestion

Week 5

Digestion

Week 6

Endocrinology

Week 7

Endocrinology

Week 8

Nervous system

Week 9

Nervous system

Week 11

Sensory functions

Week 12

Sensory functions

Week 14

Make-up labs

Recommended literature Lecture and lab notes available in pdf format Cunnigham J. G. (2007): Textbook of Veterinary Physiology. hiladelphia: W. B. Saunders Sjaastad O. V., Hove K., Sand O. (2010): Physiology of Domestic Animals. Oslo: Scandinavian Veterinary Press Swenson M. J. (2004): Dukes’ Physiology of Domestic Animals. Ithaca, London: Cornell University Press

48

SYLLABUS

VETERINARY VIROLOGY 4th Semester Course description Course

Veterinary virology

Department

Department of Microbiology and Infectious Diseases

Language

English

Nature

Mandatory

Year/semester

2nd year, spring-term

Credits (ECTS)

4

Lectures (hour/semester)

30

Plenary lectures (hour/semester) Practicals (hour/semester)

15

Responsible teacher

Petra Forgách DVM, PhD

Teacher(s)

András Marosi DVM, Mónika Somhegyiné-Barna

Prerequisites

Learning outcome (include skills and competencies, if any) Understanding of the background of viral diseases based on the general and specific characteristics of different virus families. Understanding of the laboratory methods used for the diagnostics of viral diseases.

Outcome assessment Short test at the end of each laboratory practicals; midterm at the end of the “general virology” topics (after week 6); exam at the end of semester.

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Place and significance of viruses in the biosphere, evolution of viruses.

Morphology of viruses.

Week 2

General characteristics of viral nucleic acid. Viral proteins, their role and methods of their investigation. Viral lipids and carbohydrates.

Week 3

General features of virus multiplication. Mutation of viruses and its role in virus evolution.

Week 4

Transcription, translation and nucleic acid replication of DNA and RNA viruses. Viral interactions (recombination, complementation, phenotypic mixing, interference, virus exaltation). Virus-host cell interactions, viral oncogenicity, cytopathic effects and plaque formation.

Week 5

General features of viral infection (infection routes, factors influencing the virus - host interactions). Types of viral infections (acute, latent, tolerated, persisting and slow infections). Antiviral medicines, interferons, interferon inducers and immune sera in therapy. Immunization against viral diseases, types of viral vaccines.

Week 6

Papillomaviridae, Polyomaviridae, Adenoviridae. Herpesvirales.

49

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

WEEK

Lecture topics

Week 7

Poxviridae. Asfarviridae, Hepadnaviridae, Parvoviridae, Circoviridae.

Week 8

Reoviridae, Birnaviridae. Picornavirales, Caliciviridae, Hepeviridae

Week 9

Togaviridae, Flaviviridae. Nidovirales (Coronaviridae, Arteriviridae).

Week 10

Orthomyxoviridae. Paramyxoviridae.

Week 11

Rhabdoviridae, Filoviridae. Bunyavirales, Arenaviridae, Bornaviridae.

Week 12

Retroviridae. Bakteriophages.

Week 13

Viroids, prions.

Week 14

Consultation

WEEK

Practical topics

Week 1

Plenary practical: Laboratory diagnosis of viral infections (collection and transport of samples). Direct demonstration of virus infections I (virus isolation and identification).

Week 2

Plenary practical: Direct demonstration of virus infections II (detection of viral antigens and viral nucleic acid). Laboratory practical: Virus isolation from diagnostic samples (inoculation of embryonated eggs, and cell cultures)

Week 3

Plenary practical: Titration of viruses (infective titer, hemagglutinating titer).

Detection and titration of antiviral antibodies (serumneutralization, hemagglutination inhibition). Laboratory practical: Virus-induced cytopathic effects and plaqueformation on cell cultures

Week 4

Laboratory practical: Direct diagnosis of viral infections using molecular methods I. (virus nucleic acid purification, polymerase chain reaction)

Week 5

Laboratory practical: Direct diagnosis of viral infections using molecular methods II. (agarose gel electrophoresis), indirect diagnosis of viral infections I. (virus neutralisation test)

Week 6

Laboratory practical: Indirect diagnosis of viral infections II. (evaluation of virus neutralisation, haemagglutination inhibition)

Recommended literature Fenner’s Veterinary Virology 5th edition (2016)

Note(s) The laboratory practicals are conducted at the Department’s practical room (1143 Budapest, Hungária krt. 23-25).

50

SYLLABUS

5TH SEMESTER

51

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

APPLIED ETHOLOGY 5th Semester Course description Course

Applied Ethology

Department

Animal Hygiene, Herd Health and Mobile Clinic

Language

English

Nature

Mandatory

Year/semester

3rd year, winter-term

Credits (ECTS)

3

Lectures (hour/semester)

15

Plenary lectures (hour/semester) 30 Practicals (hour/semester) Responsible teacher

Viktor Jurkovich DVM PhD dipl. ECAWBM, senior research fellow

Teacher(s)

Mikolt Bakony DVM PhD student; Eszter Losonczi DVM PhD, assistant teacher; László Kovács DVM; Boglárka Köböl DVM, invited speaker; Ágnes Sátori DVM PhD, invited speaker

Prerequisites

Learning outcome (include skills and competencies, if any) The study of applied veterinary ethology gives the students an opportunity to understand the normal or healthy behavioural characteristics of the most important farm and companion animals that occur in a normal veterinary praxis. The students will be able to evaluate the signals of bad animal welfare and the forms of abnormal behaviour on individual and herd level and also will be able to assess the environmental stress factors via examining the behaviour of the animals.

Students will learn the basics of Animal Welfare Science and animal welfare assessments.

The study of applied veterinary ethology contributes to a greater understanding of the interactions between humans and other animals and helps to create a better balance between animal welfare and the requirements that humans have of other animals.

Outcome assessment Students own work: Several topics will be offered, and some own ideas can also be worked out (covering the themes of the course: normal and abnormal behaviour of animals [mainly cattle, small ruminants, poultry, swine, horse, dog and cat], the human-animal relationships, animal welfare science, etc.).

Students need to form small groups (max 4-6 student/group) and work on their own topics: literature searching, problem description, and suggesting solutions (if it is possible).

The results of the work will be presented as a 10 min long ppt presentation during the practicals from 19th Nov. The presented topics will be discussed by the teachers and the other students, and then a score will be given for the group. The score will cover the presentation and also the capability to answer questions by the teachers and classmates.

The score will be a part of the final score at the end of the semester. So the final grade will be calculated as 25% for the presentation and 75% for the test exam at the end of the semester.

(It means that it is worth to do the work nicely) The name lists for the groups and the topics chosen should be given until 31st Oct. Exam: The course concludes with a written examination at the end of the 5th semester.

The points of the test gives 75% of the mark, 25% is coming from the points given to students own work (alltogether it takes 100 points). < 55% = fail (1), 56-65 % = passing (2), 66-80 % = fair (3), 81-90% = good (4), 91-100 % = excellent (5) 52

SYLLABUS

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

10th and 13th Sept: Behavioural traits of the domestic fowl, turkey, ducks and gees.

Correlation between behavioural requirements and housing and nutrition in poultry production.

Week 2

17th Sept: Behavioural traits of the domestic fowl, turkey, ducks and gees. Correlation between behavioural requirements and housing and nutrition in poultry production.

17th Sept: Introduction to the discipline: Veterinary Applied Ethology and Animal Welfare Science. Short history and objectives. Ethical aspects of animal production 20th Sept: Abnormal behaviour, stress and welfare. Human-animal relationship

Week 3

24th Sept: Behaviour genetics, evolution and domestication. Behaviour and physiology.

Motivation and the organisation of behaviour. General characteristics of innate behaviour. Learning and cognition, modifications of innate behaviour.

27th Sept: Social and reproductive behaviour. Abnormal behaviour.

Week 4

1st Oct: General characteristics of behaviour of sheep and goat. Connection between behaviour and housing.

1st and 4th Oct: Behavioural traits of the cattle. I. General characteristics.

Week 5

8th Oct: Behavioural traits of the cattle II. Influence of the management technology on the behaviour of dairy cattle. Abnormal behaviour of cattle.

11th Oct: Behavioural traits of the pig.

Week 6

15th and 18th Oct: Connection between management technologies and behaviour of the pigs. Abnormal behavioural traits of pigs.

Week 7

22nd and 25th Oct: Behaviour of horse. General characteristics. Connection between the environment and behaviour, abnormal forms of behaviour.

Week 8

29th Oct: Behaviour of horse. General characteristics. Connection between the environment and behaviour, abnormal forms of behaviour.

29th Oct: Behavioural characteristics of cats.

Week 9

5th Nov: Behavioural characteristics of cats. Abnormal behaviour. Treatment of malbehaviour.

8th Nov: Behavioural characteristics of dogs.

Week 10

12th and 15th Nov: Behavioural characteristics of dogs. Abnormal behaviour. Treatment of malbehaviour.

Week 11

19th and 22th Nov: Presentations of students own work

Week 12

26th and 29th Nov: Presentations of students own work

Week 13

3rd and 6th Dec: Presentations of students own work

Week 14

10th and 13th Dec: Presentations of students own work

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UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

Recommended literature Lecture notes will be uploaded to the webpage of the Unversity Recommended readings: General ethology and animal welfare: Jensen, P. 2017. The ethology of domestic animals, 3rd ed., CABI, Wallingford, UK, ISBN: 9781786391650 • Brown, JA., Sheddon, YM., Appleby, MC. 2016.

Animals and us: 50 years and more of applied ethology. Wageningen, The Netherlands, ISBN: 9789086868285 • Breed, MD., Moore, J. 2012. Animal behaviour. Academic Press, Burlington, USA • Philips, C. 2009. The Welfare of Animals. The Silent Majority. Springer, Dordrecht, The Netherlands, ISBN: 9781402092183 For more species: Ekesbo, I., Gunnarson, S. 2018. Farm animal behaviour, CABI, Wallingford, UK, ISBN: 9781786391391 • Jensen, P. 2017. The ethology of domestic animals, 3rd ed., CABI, Wallingford, UK, ISBN: 9781786391650 • Broom, DM., Fraser, AF. 2015. Domestic animal behaviour and welfare. 5th ed. CABI, Wallnigford, UK, ISBN: 978178064563 • Beaver, BV., Höglund, DL. 2016.

Efficient livestock handling. Academic Press, London, UK, ISBN: 9780124186705 Cattle behaviour and welfare: Rushen, J. et al. 2008. The welfare of cattle. Springer, Dordrecht, The Netherlands, ISBN 9781402065576 • Hulsen, J. 2006. Cow signals, Roodbond, The Netherlands, ISBN: 9075280653 • Welfare Quality. 2009. Welfare Quality assessment protocol for cattle. Welfare Quality Consortium, Lelystad, The Netherlands Pig behaviour and welfare: Marchant-Forde, J. 2009. The welfare of pigs. Springer, Dordrecht, The Netherlands, ISBN: 9781402089084 • Welfare Quality. 2009. Welfare Quality assessment protocol for cattle. Welfare Quality Consortium, Lelystad, The Netherlands Horse behaviour and welfare: McGreevy, P. 2012. Equine Behavior. 2nd ed. A Guide for Veterinarians and Equine Scientists. Saunders, ISBN: 9780702043376 • Waran, N. 2007. The Welfare of Horses.

Springer, Dordrecht, The Netherlands, ISBN: 9780306482151 Poultry behaviour and welfare: Van Horne, PLM., Achterbosch, TJ. 2008. Animal welfare in poultry production systems: impact of European Union standards on world trade. World Poultry Sci. J. 64: 40-52. • Nicol, CJ., Davies, A. Poultry welfare in developing countries. FAO Canine and feline behaviour and welfare: APPLEBY,D (2004): The APBC book of companion animal behaviour, Souvenir Press • ASKEW,H.R.(1996): Treatment of behavior problems in dogs and cats. Blackwell Science, Oxford. • Atkinson, T. (2018): Practical feline behaviour, CABI • BEAVER, B.V. (1999): Canine behavior: A guide for veterinarians, Saunders • Bradshaw, Casey, Brown (2012): Domestic cat, CABI • Fraser, A.F. (2012):Feline behaviour and welfare, CABI • HORWITZ, D, NEILSON, J.C. (2007): Canine and feline behavior (Blackwell’s five minute), Blackwell • LINDSAY, S.R. (2001): Handbook of applied dog behavior and training. Iowa State Press, Iowa. • OVERALL, K.L. (1997, 2013): Clinical behavioral medicine for small animals, Mosby Rodan I. Heath S. (2016): Feline behavioural health and welfare, Elsevier SERPELL, J.A (2006): The domestic dog: its evolution, behaviour and interactions with people, Cambridge University Press

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SYLLABUS

GENERAL PATHOLOGY 5th Semester Course description Course

General pathology

Department

Department of Pathology

Language

English

Nature

Mandatory

Year/semester

3rd year, winter-term

Credits (ECTS)

6

Lectures (hour/semester)

60

Plenary lectures (hour/semester) 0 Practicals (hour/semester)

30

Responsible teacher

Míra Mándoki

Teacher(s)

Míra Mándoki, Gyula Balka, Imre Biksi, Anna Szilasi, Péter Dobra, Ervin Albert

Prerequisites

Learning outcome (include skills and competencies, if any) General Pathology (anatomica pathologica generalis) gives us basic knowledge about the pathological changes in the body due to a disease. It deals with the disease itself, external and internal conditions leading to disease, lesions developing following a harmful stimulus. Knowing the background of the basic processes of diseases/pathological changes will help the student to further understand Internal Medicine, Surgery, Epidemiology.

Outcome assessment On the practical exam the knowledge of dissection technique is evaluated. Separately, at the semifinal oral exam, the questions asked are covering the theoretical part of the general pathology presented during the 5th semester.

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UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

Weekly schedule of lectures and practicals

56

WEEK

Lecture topics

Week 1

Objective task and investigation methods of pathology. Disease and death.

Postmortem changes. Traumas and their consequences.

Week 2

High and low temperature. Irradiations, electricity. Inadequate oxygen-, water- and nutrient supply, starvation as cause of disease. Autointoxication. Internal conditions of disease. Bacteria, viruses and fungi as cause of disease. Pathologic aspects of immunology.

Week 3

Spread of the pathological processes in the organism, septicemia, sepsis, bacteriemia.

Regressive changes: reversible and irreversible cellular and tissue changes. Necrosis, apoptosis, gangrene. Pathological calcification.

Week 4

Pathologic pigmentation. Concrements and pseudoconcrements. Edema, disturbances in water balance of cells (and the organism), disturbances in fat metabolism.

Week 5

Disturbances in carbohydrate metabolism, pathology of the diabetes mellitus.

Pathological mucus production and pathological changes in the muco-substance.

Disturbances in keratinization. Uricosis (gout). Hyalinosis, fibrinoid necrosis.

Amyloidosis.

Week 6

Local hyperemia, local oligemia (ischemia), hemostasis, shock. Hemorrhage.

Thrombosis, embolism.

Week 7

About regeneration in general. Remotion, resorption. Proliferative processes: fibrosis, fibroelastosis, elastosis, reticulosis.

Week 8

Regeneration of neural tissue, connective tissue and vessels. Wound healing.

Metaplasia, pseudometaplasia, dysplasia, hypertrophy, hyperplasia. Transformation.

Atrophy.

Week 9

Inflammation. Etiology, terminology. Vascular changes and exudation. Infiltrative and proliferative processes. Mediators. Exudative inflammation. Alterative and proliferative inflammation.

Week 10

Inflammation in organs without blood vessels. Beneficial and harmful effects; outcome and systemic sings of acute inflammation. Granulomas in general. General pathogenesis of tuberculosis, tuberculum, predominantly exudative and proliferative tuberculosis. Factors influencing the character of tuberculosis.

Week 11

Actinobacillosis, actinomycosis. Granulomas caused by fungi and chemicals.

Glanders. Disturbances in cell division. Developmental anomalies.

Week 12

General morphology of tumors. Growth and spread of tumors. Clinical effects of tumors in general. Chemical oncogenesis. Viral oncogenesis. Physical agents associated with neoplasia. Classification and nomenclature of tumors. Metastasis.

Week 13

Benign and malignant tumors of different tissues.

Week 14

Sending specimens. Histopathology. PM report.

SYLLABUS

WEEK

Practical topics

Week 1

Introduction

Week 2

General knowledge about the dissection. (Safety in the dissection room. Tools of the dissection). Description of the carcass. External and internal examination of the carcasses (until opening the abdominal cavity).

Week 3

Internal examination: dissecting the abdominal organs.

Week 4

Internal examination: dissecting the oral, cervical and thoracic organs.

Week 5

Internal examination: dissecting the urogenital organs on a male. (Discussion of the similarities and differences with a female.)

Week 6

Internal examination: dissecting the nasal cavity, skull (brain), spinal column (spinal cord). (General practice).

Week 7

Internal examination: dissecting the peripheral nerves, eyes, ears, bones, joints.

(General practice)

Week 8

General practice

Week 9

General practice. Concrements and pseudoconcrements.

Week 10

Dissection of rabbits.

Week 11

General practice. Presentation of the endocrine glands.

Week 12

General practice.

Week 13

General practice. Dissection of fetuses, fetal membranes, newborn animal carcasses.

Sending samples to a laboratory.

Week 14

Practical exam.

Recommended literature Lecture notes, Autopsy of domestic animals (practical notes), Printed notes (volume 1-3, General Pathology), Jamas F. Zachary: Pathologic Basis of Veterinary Disease (optional)

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UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

LABORATORY ANIMAL SCIENCE & BIOETHICS 5th Semester Course description Course

Laboratory Animal Science & Bioethics

Department Language

English

Nature

Mandatory

Year/semester

3rd year, winter-term

Credits (ECTS)

3

Lectures (hour/semester)

15

Plenary lectures (hour/semester) 8 Practicals (hour/semester) Responsible teacher

Prof. Dr. Sándor György Fekete

Teacher(s)

Dr. András Bersényi, Dr. Gabriella Korsós

Prerequisites

Learning outcome (include skills and competencies, if any) Basic knowledge about the zoology, behaviour, feeding and diseases of the laboratory animals.

Pain and stress recognition and alleviation. Bioethical aspects of animal experimentation. How to write a bioethical assay. Handling of laboratory animals, application of grimace score, simple experimental techniques.

Outcome assessment Personally to write a biothical assay; multiple-choice test, mini-assay / oral exam

58

SYLLABUS

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Generally about the experimental models. Questions of scientific philosophy.

Week 2

Taxonomy, biology and applied physiology of laboratory animals I.: Herbivorous and omnivorous species, incl. non-vertebrates.

Week 3

Taxonomy, biology and applied physiology of laboratory animals II.: Carnivorous species, incl. non-vertebrates.

Week 4

Alternatives to animal experimentation. The 3(4) Rs principles.

Week 5

Genetic standardisation. Speciality of transgenic animals. Control of genetic quality.

Week 6

Microbiological standardisation; the most important zoonoses.

Week 7

Requirements to environment: keeping, husbandry and hygienic levels of animal facilities and animals.

Week 8

The experimental design. Organisation and management of animal trials.

Week 9

Important animal models in basic research (e.g. Caenorhabditis elegans, Drosophila melanogaster)

Week 10

Important animal models in applied research (e.g. ob/ob, nu/nu, SCID, RAG-mouse)

Week 11

Important animal models in plurigenomics (e.g. Nutri- and epigenomics, milk composition, anticancerogenic effect, ageing)

Week 12

Well-being of laboratory animals, discomfort, stress. Recognition, prevention and alleviation of pain and suffering. Environmental enrichment. Pain categories.

Week 13

Theoretical basics of bioethics. Utilitarism, neo-kantism and the animal rights.

Ethical aspects of animal experimentation.

Week 14

Animal trials and animal protection. Authorisation of the animal trials and projects.

WEEK

Practical topics

Week 1

Basics of the anatomy of the laboratory animals (mouse, rat, guinea-pig, rabbit)

Week 2

Description, breedoing and feeding of laboratory animals. I. Herbivorous and omnivorousspecies (mouse, rat, rabbit, minipig, poultry etc.) II. Carnivorous species (ferret, cat, dog)

Week 3

Genetic calculations and examples.

Week 4

Practical laboratory animal husbandry: buildings, equipments, cages, feeders and drinkers, solid water, beddings; tools ofenvironmental enrichment.

Week 5

Handling and simple experimental techniques (mouse, rat, golden hamster, guineapig, rabbit, poultry)

Week 6

Diagnostic necropsy of laboratory animals (mostly rodents)

Week 7

Discussion about the justification of living animal experimentation versus in vitro.

Week 8

The 3Rs in analgesia, anaethesia and humane euthanasia. Cost-benefit analysis, nonprofessional summary.

Recommended literature Van Zutphen, LFM.-Bauman, V.-Beynen, AC: Priciples of Laboratory Animal Science. Elsevir.

Amsterdam, 1993, 2000.; NRC: Nutrient requirements of laboratory rodents. Washington, 1986; Svedsen, P.-Hau, J. (eds): Handbook of Laboratory Animal Science. CRS Press. Boca Raton, Fla, 1994, 2004; Regan, T.: The case of animal rights. Univ. Calif. Press. Berkeley, Los Angeles, 1983; Fekete, SGy: Feeding and Nutrition of the Laboratory Rabbit. In: DeBlas, C-Wiseman, J.: The Nutrition of the Rabbit. CABI Publ. Oxon-New York, 2019

59

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

VETERINARY BACTERIOLOGY 5th Semester Course description Course

Veterinary bacteriology

Department

Department of Microbiology and Infectious Diseases

Language

English

Nature

Mandatory

Year/semester

3rd year, winter-term

Credits (ECTS)

4

Lectures (hour/semester)

30

Plenary lectures (hour/semester) Practicals (hour/semester)

30

Responsible teacher

Makrai, Lรกszlรณ

Teacher(s)

Adorjรกn, A., Fodor, L., Makrai, L., Tรณth, A., Tรณth, G.

Prerequisites

Learning outcome (include skills and competencies, if any) After absolving the subject the students will be able to recognise the most important bacteria and fungi of veterinary and human relevance, carry out laboratory examinations in order to identify them, understand the role of bacteria and fungi in life, in pathology, physiology, nutrition and ecology, implement disinfection and sterilisation methods, understand the principles of antibacterial treatments, understand the pathological consequences of genetic changes of bacteria.

Outcome assessment There are written and oral tests at the practical and the subject is closed with an exam at the end of the semester.

Weekly schedule of lectures and practicals

60

WEEK

Lecture topics

Week 1

Characterization of bacteria, their importance in life. Size and shape of bacteria.

Structure of the bacterial cell .

Week 2

Staining of bacteria, Bacillus anthracis and aerobic spore-forming bacteria.

Clostridium.

Week 3

Staphylococcus, Micrococcus, Streptococcus, Enterococcus, Lactococcus, Anaerobic cocci, Lactobacillus, Erysipelothrix, Listeria .

Week 4

Mycobacterium, Nocardia, Actinomyces, Trueperella, Actinobaculum, Dermatophilus, Streptomyces, Corynebacterium, Rhodococcus, Renibacterium.

Week 5

General characterisation of Enterobacteriaceae. Escherichia, Klebsiella, Enterobacter.

Week 6

Metabolism of bacteria, autotrophic and heterotrophic bacteria. Carbohydrate metabolism of bacteria. Nitrogen metabolism of bacteria. Lipid metabolism, vitamin and additive demand, pigment production. Practical use of bacterial activity.

SYLLABUS

WEEK

Lecture topics

Week 7

Growth and multiplication of bacteria. Environmental effects on multiplication.

Resistance of bacteria against physical effects. Disinfection.

Week 8

Genetics of bacteria. Examination of bacteria using molecular methods.

Week 9

Pasteurella, Mannheimia, Bibersteinia, Ornithobacterium, Riemerella, Actinobacillus, Haemophilus, Histophilus, Avibacterium, Taylorella. Identification of an unknown bacterium I.

Week 10

Brucella, Pseudomonas, Burkholderia, Aeromonas, Francisella, Bordetella, Moraxella.

Identification of an unknown bacterium II.

Week 11

Vibrio, Campylobacter, Lawsonia, Helicobacter, Arcobacter, Spirochaetes.

Bacteriological examination of pathological samples I.

Week 12

Mycoplasma, Rickettsia, Chlamydia. Bacteriological examination of pathological samples II.

Week 13

Fungi.

Week 14

Pathogenicity and infection.

WEEK

Practical topics

Week 1

Media, sterilization of media and utensils, bacterial cultures, anaerobic culture methods, pure cultures, microscopy, examination of native bacteria.

Week 2

Media, sterilization of media and utensils, bacterial cultures, anaerobic culture methods, pure cultures, microscopy, examination of native bacteria.

Week 3

Bacillus anthracis and aerobic spore-forming bacteria. Clostridium.

Week 4

Staphylococcus, Micrococcus, Streptococcus, Enterococcus, Lactococcus, Anaerobic cocci, Lactobacillus, Erysipelothrix, Listeria .

Week 5

Mycobacterium, Nocardia, Actinomyces, Trueperella, Actinobaculum, Dermatophilus, Streptomyces, Corynebacterium, Rhodococcus, Renibacterium.

Week 6

General characterisation of Enterobacteriaceae. Escherichia, Klebsiella, Enterobacter.

Week 7

Antibacterials. Examination of antibacterial resistance.

Week 8

Salmonella, Citrobacter, Shigella, Proteus, Providentia, Yersinia, Serratia, Edwardsiella, anaerobic Gram-negative rods.

Week 9

Salmonella, Citrobacter, Shigella, Proteus, Providentia, Yersinia, Serratia, Edwardsiella, anaerobic Gram-negative rods.

Week 10

Pasteurella, Mannheimia, Bibersteinia, Ornithobacterium, Riemerella, Actinobacillus, Haemophilus, Histophilus, Avibacterium, Taylorella. Identification of an unknown bacterium I.

Week 11

Brucella, Pseudomonas, Burkholderia, Aeromonas, Francisella, Bordetella, Moraxella.

Identification of an unknown bacterium II.

Week 12

Vibrio, Campylobacter, Lawsonia, Helicobacter, Arcobacter, Spirochaetes.

Bacteriological examination of pathological samples I.

Week 13

Mycoplasma, Rickettsia, Chlamydia. Bacteriological examination of pathological samples II.

Week 14

Fungi.

Recommended literature The detailed recommended literature is available on the homepage.

61

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

VETERINARY LABORATORY DIAGNOSTICS 5th Semester Course description Course

Veterinary Laboratory Diagnostics

Department

Department of Clinical Pathology and Oncology

Language

English

Nature

Mandatory

Year/semester

3rd year, winter-term

Credits (ECTS)

1

Lectures (hour/semester)

0

Plenary lectures (hour/semester) Practicals (hour/semester)

30

Responsible teacher

Dr. Péter Vajdovich

Teacher(s)

Dr. Krisztina Kungl (contact person for students: Kungl.krisztina@univet.hu), dr. Márton Márialigeti, dr. Milán Miskolczi, dr. Péter Vajdovich

Prerequisites

Learning outcome (include skills and competencies, if any) To provide general knowledge about laboratory methods, and parameter specific knowledge: when a parameter should be requested (indications and contraindications), what lab method is used to determine the given parameter (analyzers), what is the reference range, interpretation of abnormal results, causes of bias.

Outcome assessment Oral exam - the student is required to know and apply the above gained knowledge

62

SYLLABUS

Weekly schedule of lectures and practicals

WEEK

Practical topics

Week 1

Isovolaemia, isoosmosis: PCV, ion concentrations

Week 2

Isohydria: acid-base balance, blood gas analysis

Week 3

Haemostasis tests

Week 4

Examinations on metabolic disorders

Week 5

Evaluation of red blood cells

Week 6

Evaluation of inflammation and white blood cells

Week 7

Examination of the body cavity fluids and the cerebrospinal fluid

Week 8

Examination of ruminal fluid

Week 9

Examination of the intestinal function and the exocrine pancreas

Week 10

Examination of the liver 1.

Week 11

Examination of the liver 2.

Week 12

Examination of the kidney function

Week 13

Urinalysis

Week 14

Examination of endocrine disorders

Recommended literature Lecture notes are available for download on the web site of the department/faculty; Elizabeth Villiers (Editor), Laura Blackwood (Editor). BSAVA Manual of Canine and Feline Clinical Pathology; Veterinary Haematology and Clinical Chemistry, Mary Anna Thrall, Glade Weiser, Robin Allison, Terry W. Campbell, John Wiley & Sons, 2012.

Note(s) All other important info (e.g. retakes, materials) can be found in the GENERAL INFO SHEET for Laboratory diagnostics on the department website and will be distributed by the year representative.

- To the practicals students must come prepared from the material of the given day. Oral or written questioning occurs on every practical.

- It is not possible to change the date of the midterms (the dates were adjusted with the studentsâ&#x20AC;&#x2122; secretariat).

63

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

VETERINARY PATHOPHYSIOLOGY 5th Semester Course description Course

Veterinary Pathophysiology

Department

Department of Clinical Pathology and Oncology

Language

English

Nature

Mandatory

Year/semester

3rd year, winter-term

Credits (ECTS)

4

Lectures (hour/semester)

45

Plenary lectures (hour/semester) Practicals (hour/semester)

0

Responsible teacher

Dr. Péter Vajdovich

Teacher(s)

dr. Arany-Tóth Attila, dr. Horváth András, dr. Kungl Krisztina (kapcsolattartó: Kungl.krisztina@univet.hu), dr. Manczur Ferenc, dr. Márialigeti Márton, dr. Máthé Ákos, dr. Miskolczi Milán, dr. Psáder Roland, dr. Sterczer Ágnes, dr. Tarpataki Noémi, dr. Vajdovich Péter, dr. Vörös Károly

Prerequisites

Learning outcome (include skills and competencies, if any) To provide understanding and knowledge on how pathologic processes (e.g. inflammation etc.) occur and impact the whole of the organism and the specific organ systems.

Outcome assessment Written exam test and essay - displaying the student’s knowledge and understanding of pathological processes.

Weekly schedule of lectures and practicals

64

WEEK

Lecture topics

Week 1

The subject of pathophys., alterations of isovolaemia and isoosmosis Disturbances in water balance. Edema Ion balance and its alterations I. (Na+, K+, Cl-)

Week 2

Ion balance and its alterations II. (Ca2+, Mg2+, PO42-) Ion balance and its alterations III. (Ca2+, Mg2+, PO42-) Pathophysiology of the general adaptation syndrome and the stress Thermoregulation disorders, heat stroke and fever

Week 3

Damages of the antioxidant system Pathophysiology of pain Disorders of haemostasis I (Thrombocytopathies) Disorders of haemostasis II (Coagulopathies, DIC)

Week 4

Disturbances in general metabolism and amino acid - protein metabolism Disturbances in carbohydrate metabolism Disturbances in fat metabolism

SYLLABUS

WEEK

Lecture topics

Week 5

Pathophysiology of allergy, pruritus and the skin disorders Anaemia I. - Disturbances of O2 transport and the blood loosing anaemia Anaemia II. - Haemolytic deficieny and non regenerative anaemia

Week 6

Alterations of white blood cells Pathophysiology of inflammation 1.

Pathophysiology of inflammation 2.

Abnormal food prehension, chewing and swallowing

Week 7

Disturbances of the ruminal carbohydrate, nitrogen and lipid metabolism Disturbances of forestomach motility Ruminal bloat. Abomasal dysfunctions

Week 8

Disturbances of the monogastric stomach, vomiting Intestinal motility disorders, constipation, ileus, increased peristalsis Disturbances of intestinal digestion, maldigestion, malabsorption and diarrhoea

Week 9

Disturbance of liver functions, jaundice Hepatopathies of vascular origin, ascites Altered protein, carbohydrate and lipid metabolism in the liver

Week 10

Muscular dysfunctions Adaptation of the heart and their limits, heart failure Pathophysiology of arrhythmias

Week 11

Renal disturbances, glomerulopathies I. Renal disturbances, tubular malfunctions II. Renal insuff. of birds and raptiles: gout, disturbances of the lower urinary tract

Week 12

Disorders of the external breathing I. (ventilation and perfusion, hypoxaemias) Disorders of the external breathing II. Pathophysiological basis of reflex abnormalities

Week 13

Osteopathies Disturbances of spinal cord functions Malfunction of the synapses

Week 14

Disturbances of brain functions Pathoendocrinology I. (diabetes mellitus, insipidus, Cushingâ&#x20AC;&#x2122;s disease) Pathoendocrinology II. (hypo-, and hyperthyroidism, rare endocrinopathies)

Recommended literature Lecture notes available from the official website of the department in pdf.

Robinson, W.,F., Huxtable, C.R.R. (2003): Clinicopathological principles for veterinary medicine.

Cambridge University Press, Cambridge. McGavin, Zachary, Pathologic basis of Veterinary Disease IV. ed. (2007, Moosby)

Note(s) Laboratory Diagnostics and Veterinary Pathophysiology are closely related to each other. The lecture programme is arranged to match the themes of the practicals from LabD. Attending the lectures helps a lot to prepare for the practicals and learning for practicals makes Pathophys. exam much easier!

65

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

VETERINARY PHARMACOLOGY 1 5th Semester Course description Course

Veterinary pharmacology 1

Department

Department of Pharmacology and Toxicology

Language

English

Nature

Mandatory

Year/semester

3rd year, winter-term

Credits (ECTS)

6

Lectures (hour/semester)

40

Plenary lectures (hour/semester) Practicals (hour/semester)

30

Responsible teacher

Dr. Ákos Jerzsele

Teacher(s)

Dr. Ákos Jerzsele, Dr. György Csikó, Dr. Orsolya Farkas, Dr. Erzsébet Gere, Dr. Zita Karancsi, Dr. Adrienn Mercédesz Veres, Dr. Dóra Kovács, Dr. Zoltán Somogyi

Prerequisites

Learning outcome (include skills and competencies, if any) The course puts strong emphasis on pharmacological and pharmakokinetic aspects of the approriate drug selection in the causative and symptomatic treatment of various animal diseases.

After completing the course, veterinary students will have a broad knowledge of the mode of interaction of drugs with their target proteins and they can understand both theoretical background and practical importance of safe and effective drug applications. Pharmacology 1 will include information of drugs targeting cardiovascular system, hemopoiesis, central and peripheral nervous system, gastrointestinal, respiratory and urinary tract, endocrine system classified according to different animal species and gives detailed description of vitamins, minerals. The practicals facilitate acquirement of solid knowledge how to write prescriptions, which dose forms can be prescribed, how the drugs can be applied in various animal species.

Outcome assessment During the practicals, students have to be able to answer the questions about the topic of former and actual practical satisfactory either verbal or written (weekly test, quiz). Furthermore, the midterm tests will focus on the students’ acquired knowledge about the lectures’ material.

66

SYLLABUS

Weekly schedule of lectures and practicals

WEEK Week 1

Week 2

Week 3

Week 4

Week 5

Week 6

Week 7

Week 8

Week 9

Week 10

Week 11

Week 12

Week 13

Week 14

Lecture topics General Pharmacology Pharmacodynamics: Structure-dependent and independent drug actions Drug-receptor interactions Dose-response relationship, therapeutic concepts Pharmacokinetics: Mechanisms of drug transport, absorption, distribution Drug metabolism and excretion Pharmacokinetic modelling Principles of pharmacotherapy Factors influencing drug efficacy Detailed Pharmacology Neuropharmacology, CNS stimulants CNS inhibitor drugs, tranquilizer sedatives Hypnosedatives Anticonvulsive drugs, Antiepileptics Pharmacology of pain: Opioids 1.

Opioids 2.

Local anaesthetics General anaesthetics Injectable anaesthetics Inhalational anaesthetics Central and peripherial myorelaxant drugs Pharmacology of the parasympathetic nervous system (parasympathomimetics) Pharmacology of the parasympathetic nervous system (parasympatholytics) Pharmacology of the sympathetic nervous system (sympathomimetics, sympatholytics) Pharmacology of inflammation: Pharmacology of NSAIDs Pharmacology of glucocorticoids Pharmacology of antihistamines JAK inhibitors and other anti-inflammatory agents Pharmacology of immunosuppression Pharmacology of the respiratory system: Bronchodilators, anti-inflammatory drugs of the respiratory system Antitussive drugs, mucolytics and expectorants.

Pharmacology of the cardiovascular system: Pharmacology of arrhythmias Pharmacology of cardiac contractility (positive inotropic drugs) Pharmacology of vascular tone Pharmacology of volume regulation Diuretics Pharmacology of haemostasis and thrombosis Pharmacology of haematopoiesis. Treatment of anaemia Pharmacology of the digestive system: Emetic and antiemetic drugs.

Prokinetic agents, drugs for gastric and duodenal ulcers.

Laxative drugs, antidiarrheal drugs Hepatoprotective drugs Pharmacology of the endocrine system: Pharmacology of the hypophyseal and pituitary gland hormones and analogues Pharmacology of the thyroid gland and adrenal gland hormones Pancreatic hormones, drugs affecting blood glucose level Pharmacology of gonadal hormones Drugs affecting uterine function

67

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

WEEK

Practical topics

Week 1

Sources of drugs in veterinary medicine. Storage, stability, sales of drugs.

Week 2

Prescription writing, legal aspects, scheduled drugs

Week 3

Forms of prescriptions

Week 4

Dosage forms I. â&#x20AC;&#x201C; solid dosage forms

Week 5

Dosage forms II. â&#x20AC;&#x201C; semi-solid, liquid and gaseous dosage forms

Week 6

Basic knowledge of drug preparation

Week 7

Theory and practice of drug administration

Week 8

30th Oct. 7:00 am Test 1 (central nervous system inhibitors)

Week 9

Clinical pharmacology and demonstration regarding sedative and hypnotic drugs, Drug development Short presentations

Week 10

Clinical pharmacology and demonstration regarding anesthetics and anticonvulsive drugs Short presentations

Week 11

Ocular pharmacology

Week 12

27th Nov. 7:00 am Test 2 (Pharmacology of inflammation, respiratory and cardiovascular system)

Week 13

Clinical pharmacology of the digestive system Short presentations

Week 14

Drug interactions and incompatibilities in the veterinary practice + Consultation, retake of missed or cancelled practicals

Recommended literature Handouts, notes and other files available on the home page.

68

SYLLABUS

6TH SEMESTER

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UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

ANIMAL NUTRITION 1 6th Semester Course description Course

Animal Nutrition 1

Department Language

English

Nature

Mandatory

Year/semester

3rd year, spring-term

Credits (ECTS)

3

Lectures (hour/semester)

30

Plenary lectures (hour/semester) Practicals (hour/semester)

15

Responsible teacher

Mr. István HULLÁR associate professor, head of Division for Animal Nutrition and Clinical Dietetics

Teacher(s)

Mr. Sándor György FEKETE, full professor Mrs. Éva CENKVÁRI, senior research fellow Mrs. Orsolya KORBACSKA-KUTASI associate professor Mrs. Nikoletta HETÉNYI research fellow Mr. András BERSÉNYI, assistant professor Mrs. Hedvig FÉBEL, invited private professor

Prerequisites

Learning outcome (include skills and competencies, if any) An understanding of fundamentals of animal nutrition. It involves the chemical compounds of feeds, methods of feed analysis, protein and energy evaluations, regulation of feed intake, nutrients’ digestibility, microflora and -fauna in rumen and in gut, antinutritive substances in feeds, growth promoters, deterioration of feeds, metabolic function of essential minerals, vitamins, symptoms of deficiency or toxicity, relationship between nutrition and reproduction, immunology, and food safety. The complete knowledge of feeds, and guidelines for ration formulation are also involved.

Outcome assessment Possible forms of the “Animal Nutrition 1” exam: 1. Written exam (test) Grading scheme: Mark % excellent (5) 90-100 , good (4) 80-89, fair (3) 70-79, passing (2) 60-69, failure (1) 0-59 Please note that every year new tests will be compiled, consequently knowing the questions of the previous test only does not guarantee the passing.

2. Oral exam Those who − do not want to do the exam in written form or − cannot take part on the test or − fail on the test, will get oral exam dates via NEPTUN. Exam dates will be published throught the NEPTUN shortly after the beginning of each academic semester.

The form of oral exam from “Animal Nutrition 1”: each student gets 1-1 question (i.e. altogether 3) from the following 3 question groups.

1. Fundamentals of animal nutrition. 2. Vitamins, minerals. 3. Feedstuffs.

The oral exam from feedstuffs involves the identification of feed as well. Feeds to be identified will be available in the Student Centre one week before the onset of the exam period.

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SYLLABUS

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Introduction, chemical compounds of feeds (proximate analysis), fibre fractions (NDF, ADF, ADL).

Week 2

Energetic evaluation of feeds.

Week 3

Protein evaluation systems: monogastric animals + ruminants.

Week 4

Regulation of the feed intake, nutrientsâ&#x20AC;&#x2122; digestibility.

Week 5

Microflora and -fauna in rumen and in gut. Interaction between the intestinal flora and feed: eubiosis, dysbiosis. Microbiology and mycology of feedstuffs.

Week 6

Generally about vitamins, fat soluble vitamins.

Week 7

Water soluble vitamins.

Week 8

Homeostasis of minerals, control of mineral supply. Earth alkali alkalinity, cationanion balance of rations, clinical effects.

Week 9

Macrominerals, microminerals.

Week 10

Antinutritive substances in feeds, and antimetabolites. Deterioration of feeds (rancidity), warranty and guarantees. Microbial deterioration of feeds, mycotoxins.

Week 11

Growth promoters, pro- and prebiotics, nutriceuticals.

Week 12

Immunological aspects of animal nutrition.

Week 13

Relationship between feeding and reproduction.

Week 14

Animal nutrition and food safety.

WEEK

Practical topics

Week 1

Definition and classification of feedstuffs, mineral and vitamin supplements, manufactured feeds.

Week 2

Cereal grains, and grain legumes.

Week 3

Hay and haymaking, meadow hay, alfalfa hay.

Week 4

Pasture grasses, and harvested green forages. Straws, roots and tubers.

Week 5

The Fill Unit System (UE), Substitution Number (SN), Index of Nutritional Quality (INQ). Oilseed (solvent extracted) meals.

Week 6

Energetic evaluation of feeds. I. Monogastric animals - calculations. By-products of starch industry and fruit processing.

Week 7

Energetic evaluation of feeds. II. Ruminants - calculations. Distillery and brewery byproducts.

Week 8

Protein evaluation of feeds. I. Monogastric animals - calculations. Milling by-products of cereal grains. Antioxidants, amino acid and enzyme supplements.

Week 9

Protein evaluation of feeds. II. Ruminants - calculations. Use of NPN (Non Protein Nitrogen) supplementation.

Week 10

Nutrients' digestibility - calculation. By-products of sugar industry.

Week 11

Silage making, maize silage.

Week 12

Control of the mineral supply, calculation of the Cation-Anion Balance.

Week 13

Feed sampling, feed microscopy. Feedstuffs of animal origin.

Week 14

Guidelines and rules for ration formulation. Ration formulation by computer.

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Recommended literature Obligatory: Handouts, and your own notes made on lectures and practicals. Further reading: S. Gy. Fekete (Ed.): Veterinary Nutrition and Dietetics. Fac. Vet. Sci., Szent IstvĂĄn Univ., Budapest, 2008.

P. McDonald, R.A. Edwards, J.F.D. Greenhalgh, C.A. Morgan, L.A. Sinclair, R.G. Wilkinson: Animal Nutrition. Prentice Hall, 11th Edition, 2011.

Note(s) Attendance at lectures and practicals Lectures: According to the decision of the Faculty Council (14 November 2006) attendances at lectures are also obligatory.

The acceptable numbers of uncertifd absences are maximum 3 per semester. With more than three (3) recorded absences your semester is NOT going to be accepted for that subject thus it has to be re-taken during a later semester for an additional fee in order to sit for the exam.

Absences because of clinical practices or research activity connected to the diploma thesis are not treated as uncertified absences, but these must be verified on the official certificate by the teacher or the tutor.

Practicals: The Department registers the attendance at the beginning of each single practical by using the official group assignment provided by the Studentâ&#x20AC;&#x2122;s Secretariat.

With more than 4 recorded absences your semester is NOT going to be accepted for that subject, thus it has to be retaken during a later semester for an additional fee in order to sit for the exam.

One practical per semester can be missed without any consequence. In case of more absences, the student has to give an account of the subject of missed practical within 2 weeks at the lecturer of the topic. According to these, no more than 4 missed practicals will be accepted from which accounts of 3 have to be given.

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SYLLABUS

EQUINE MEDICINE AND SURGERY 1 6th Semester Course description Course

Equine Medicine and Surgery 1

Department Language

English

Nature

Mandatory

Year/semester

3rd year, spring-term

Credits (ECTS)

3

Lectures (hour/semester)

30

Plenary lectures (hour/semester) 12 Practicals (hour/semester)

33

Responsible teacher

Gábor Bodó

Teacher(s)

Zoltán Bakos, Zita Makra, Péter Tóth, Simon Ízing, Pál Tuska,

Prerequisites

Learning outcome (include skills and competencies, if any) basic knowledge in equine radiology, wound management, equine anaesthesia and clinical examination of the horse

Outcome assessment written exam + oral practical exam from equine internal medicine and surgery Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Radiation safety, general knowledge in equine radiography (2 hours); Basic clinical values, examination of the skin, Examination of the lymponodes and the mucus membran in horses (2 hour)

Week 2

Radiological examination of the front limb (2 hours) Examination of the lung (2 hours)

Week 3

Radiological examination of the hind lim limb (2 hours) Examination of the cardiovascular system, examination of the gastrointestinal tract I. (2 hours)

Week 4

Radiological examination of the head, neck and thoracolumbal area (2 hours) Examination of the gastrointestinal tract II. , examination of the nervous system I. (2 hours)

Week 5

Classification and management of open wounds (2 hours) Examination of the nervous system II. Examination of the urogenital tract (2 hours)

Week 6

Wound healing, wound healing complications, infected wounds (2 hours) Examination and decision making by the emergency injured patient, wound management (2 hours)

Week 7

Local anesthesia in veterinary medicine, patient examination before GA (2 hours) Different anesthethic protocols in large animals (2 hours)

Week 8

Perioperative monitoring, anesthesia of risiko patients (2 hours)

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WEEK

Practical topics

Week 1

Radiological examination in horses I. How to interpret X-rays. (3 hours) How to deal with horses, restraint of horses, how to take the basic clinical values (3 hours) Radiological examination of the front limb (3 hours)

Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8 Week 9 Week 10 Week 11 Week 12 Week 13 Week 14

Radiological examination of the hind limb (3 hours) Examination of the skin, lymponodes and the mucus membran in horses (3 hours) Radiological examination of the vertebral column (3 hours) Orthopedic ultrasound examination in horses (3 hours) Examination of the airways, endoscopic and utrasonographic examination (3 hours) Examining the injured patient, bandage course (3 hours) Examination of the cardiovascular system, EKG, echocardiography (3 hours) Practicing different suturing techniques on cadaver limbs (3 hours) Examination of the GI tract, rectal examination, gastroscopy, ultrasonography (3 hours) Practicing different suturing techniques on cadaver small intestines (3 hours) Examination of the nervous system, self-dependent clinical examination of the equine patient (3 hours) Structure of the large animal anesthetic mashine, anesthesia of equine patients

Recommended literature - Auer, J. A. Stick J: Equine surgery. 5th edition, Elsevier, Philadelphia, 2018.

- Butler, J. A. ( et. al.) : Clinical radiology of the horse. 3nd edition, Blackwell Science, 2008 - Donald, E. Thrall: Textbook of Veterinary Diagnostic Radiology. 6th edition, Elsevier, 2012 - Hall, L.W. - Clarke, K. N.: Veterinary anaesthesiology. 9th edition, Wiley and Blackwell, 2008 - Muir W . W. Hubbel, J. A. E. : Handbook of Veterinary Anesthesia. 5th edition, Elsevier Mosby, 2013 - Robinson, N. E.: Currrent therapy in equine medicine 7th edition. Philadelphia, Saunders 2015 - Stashak, T. S.: Equine wound management. 2nd edition, Wiley and Blackwell, 2011 - Traub-Dargats, J. L - Brown, C. M.: Equine endoscopy. 2nd revised edition, Elsevier 1996 - Reed, S.M., Bayly, W.M., Sellon, D.C.: Equine Internal Medicine 4th Ed. 2017

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SYLLABUS

SMALL ANIMAL MEDICINE 1 6th Semester Course description Course

Small Animal Medicine 1

Department

Department of Internal Medicine; Department of Surgery and Ophthalmology

Language

English

Nature

Mandatory

Year/semester

3rd year, spring-term

Credits (ECTS)

5

Lectures (hour/semester)

60

Plenary lectures (hour/semester) 2 Practicals (hour/semester)

45

Responsible teacher

Dr. Ferenc Manczur

Teacher(s)

Prof. Dr. Tibor NĂŠmeth, Dr. Ă gnes Sterczer

Prerequisites

Learning outcome (include skills and competencies, if any) Basic clinical examination (signalment, history, physical and supplementary exams of different organ systems); diagnostic imaging skills (radiology, ultrasonography, endoscopy, ECG, echocardiography); anesthesia skills (preanesthetic examination, anesthetic machines, monitoring devices and procedures, anesthetic protocols).

Outcome assessment semi-final exam (written and oral parts) Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

The aim and methods of the clinical examinations of the different organs; different types of diagnoses; general radiology

Week 2

Parts of the history (anamnesis). Parts of the status praesens. General impression.

Basic clinical values, Radiology of bones and joints

Week 3

Examination of the lymph nodes and mucous membranes; Examination of the respiratory system I; Radiology of the vertebral coloumn and the skull

Week 4

Examination of the respiratory system II-III; Radiology of the abdomen

Week 5

Examination of the respiratory system IV: Examination of the respiratory system by percussion. Respiratory endoscopy; Radiology of the thorax I

Week 6

Examination of the cardiovascular system II; Radiology of the thorax II

Week 7

Examination of the cardiovascular system III; Preanesthetic examination; Pharmacology of anesthetics I

Week 8

Basics of ECG analysis plenary lecture; diagnostic ultrasound, echocardiography; Pharmacology of anesthetics II

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WEEK

Lecture topics

Week 9

Examination of the canine and feline digestive system. Ultrasonography of the abdominal organs. Gastrointestinal endoscopy; Perioperative analgesia, monitoring, syringe pumps and anesthetic machines

Week 10

Examination of urogenital system; anesthesia protocols in small animals I

Week 11

Examination of endocrine organs and the spleen; anesthesia protocols in small animals II

Week 12

Examination of the nervous system I-II; Anesthesia of risk pations and emergency in small animals

Week 13

Examination of the nervous system III-IV

Week 14

Examination of nervous system V; Examination of the skin

WEEK

Practical topics

Week 1

Handling and restraining of dogs and cats. Safety regulations. Taking the signalment, nationale. Determining the basic clinical values. Studying different histories, anamnesis. Principles of radiographic techniques

Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8 Week 9 Week 10 Week 11 Week 12 Week 13 Week 14

Examination of the mucous membranes and the lymph nodes of dogs and cats.

Examination of the respiratory system of small animals: Examination of the nose and the nasal cavities. Inducing cough in healthy and sick animals. Examination of the larynx and the trachea Radiation safety. Positioning in small animal radiography Auscultation over the larynx, trachea and thorax of healthy and sick animals.

Percussion of the thorax. Examination of the cardiovascular system of healthy and sick dogs and cats. Contrast procedures in small animal radiology Examination of the urinary system of the small animals. Interpretation of radiographs Examination of the nervous system of small animals. Examination of the skin.

Practical small animal anaesthesiology I Practicing the clinical examination of dogs and cats: Documentation of the status praesens. Practical small animal anaesthesiology II Consultations

Recommended literature Donald, E. Thrall: Textbook of Veterinary Diagnostic Radiology. 6th edition, Elsevier, 2012; Muir W . W. Hubbel, J. A. E. : Handbook of Veterinary Anesthesia. 5th edition, Elsevier Mosby, 2013

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SYLLABUS

PARASITOLOGY 1 6th Semester Course description Course

Parasitology 1

Department

Parasitology and Zoology

Language

English

Nature

Mandatory

Year/semester

3rd year, spring-term

Credits (ECTS)

4

Lectures (hour/semester)

45

Plenary lectures (hour/semester) 0 Practicals (hour/semester)

30

Responsible teacher

Prof. Dr. Rรณbert Farkas

Teacher(s)

Prof. Dr. Rรณbert Farkas, Dr. Sรกndor Hornok

Prerequisites

Learning outcome (include skills and competencies, if any) The principal theoratical and practical knowledge of the parasitic diseases of domestic animals caused by helminths.

Outcome assessment Practical mark in parasitology at the end of the 6th semester which will be calculated from the results of the two practical midterm exams.

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Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Introduction to parasitology. Taxonomy of Protozoa. â&#x20AC;&#x17E;SARCOMASTIGOPHORAâ&#x20AC;?

Tropical trypanosomoses, dourine

Week 2

Leishmaniosis. Giardiosis. Bovine and avian trichomonosis Histomonosis. Amoeboses

Week 3

APICOMPLEXA. Eimeriidae: coccidiosis of the chicken.

Control of chicken coccidiosis, coccidiosis of other birds

Week 4

Coccidiosis of the horse, cattle, small ruminants, rabbit, pig, carnivores.

Cryptosporidiosis

Week 5

Toxoplasmosis. Neosporosis. Hammondiosis. Besnoitiosis. Sarcocystiosis I.

Week 6

Sarcocystiosis II. Klossiellosis. Hepatozoonosis. Malaria. Haemoproteosis.

Leucocytozoonosis. Babesiosis

Week 7

Theileriosis. Cytauxzoonosis. MICROSPORA: encephalitozoonosis.

CILIOPHORA: balantidiosis. Blastocystiosis. Summarizing review of protozoa

Week 8

Introduction to veterinary entomology. Lice. Fleas

Week 9

Bugs. Darkling beetle. Mosquitoes. Blackflies. Biting midges. Sandflies

Week 10

Horse- and deerflies. Tsetse flies. Forest flies "

Week 11

Muscoid flies. Myiasis-causing fly species. Traumatic myiasis

Week 12

Hypodermosis. Gasterophilosis. Oestrosis. Mange mites II.

Week 13

Demodectic mites. Soft and hard ticks

Week 14

Cheyletiella, red and other mites. The tongue worm. Control of arthropods

WEEK

Practical topics

Week 1

Basic terms. Diagnostic techniques in protozoology

Week 2

Trypanosomosis, leishmaniosis, giardiosis, trichomonosis, histomonosis (T)

Week 3

Investigation of coccidia, coccidiosis of chicken, goose (T)

Week 4

Coccidiosis of cattle, rabbit, pig and carnivores (T)

Week 5

Cryptosporidiosis, toxoplasmosis, besnoitiosis of cattle, sarcocystiosis (T)

Week 6

Hepatozoonosis of dog, babesiosis, theileriosis, encephalitozoonosis (T)

Week 7

Practical examination

Week 8

Examination for arthropods of veterinary importance. Lice, fleas (T)

Week 9

Bugs, beetle. Mosquitoes, blackflies, biting midges, sandflies, horse- and deerflies, tsetse flies, forest flies, the sheep ked (T)

Week 10

Muscoid flies, traumatic and other myiases (T)

Week 11

Mange (T)

Week 12

Demodectic mites, soft and hard ticks and other mites(T)

Week 13

Practical examination

Week 14

Summarizing review of protozoa andarthropods

Recommended literature Peter Deplazes, Johannes Eckert, Alexander Mathis, Georg von Samson-Himmelstjerna, Horst Zahner: Parasitology in Veterinary Medicine. 2016. Wageningen Academic Publisher, The Netherlands

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SYLLABUS

PATHOLOGY 1 6th Semester Course description Course

Pathology 1

Department

Department of Pathology

Language

English

Nature

Mandatory

Year/semester

3rd year, spring-term

Credits (ECTS)

2

Lectures (hour/semester)

15

Plenary lectures (hour/semester) Practicals (hour/semester)

30

Responsible teacher

Míra Mándoki

Teacher(s)

Míra Mándoki, Gyula Balka, Imre Biksi, Anna Szilasi, Péter Dobra, Ervin Albert

Prerequisites

Learning outcome (include skills and competencies, if any) Special pathology is discussing the pathologic background of diseases detailed, organized by organ systems, emphasizing the differences between species. In this semester, the first half of the Mammalian special pathology is lectured.

Outcome assessment There is no examination at the end of this semester. Students can discuss questions that may come up during small group practicals, or at consultation appointments.

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Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Pathology of the oral cavity 1.

Week 2

Pathology of the oral cavity 2.

Week 3

Pathology of the teeth and and the oesophagus

Week 4

Pathology of the forestomachs

Week 5

Pathology of the stomach

Week 6

Pathology of the intestines 1.

Week 7

Pathology of the intestines 2.

Week 8

Pathology of the intestines 3.

Week 9

Pathology of the intestines 4.

Week 10

Pathology of the intestines 5.

Week 11

Pathology of the intestines 6.

Week 12

Pathology of the pancreas

Week 13

Pathology of the liver 1. Pathology of the spleen

Week 14

Pathology of the liver 2.

WEEK

Practical topics

Week 1 Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8

General practice on all practicals according to the available carcasses.

Description of the pathologic lesions.

Week 9 Week 10 Week 11 Week 12 Week 13 Week 14

Recommended literature Lecture notes, Ferenc Vetési-Mihály Dobos-Kovács: Colour Atlas of Veterinary Pathology I., Jubb, Kennedy and Palmer’s: Pathology of Domestic Animals Volumes 1-3 (optional)

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VETERINARY IMMUNOLOGY 6th Semester Course description Course

Veterinary Immunology

Department

Department of Microbiology and Infectious Diseases

Language

English

Nature

Mandatory

Year/semester

3rd year, spring-term

Credits (ECTS)

4

Lectures (hour/semester)

30

Plenary lectures (hour/semester) Practicals (hour/semester)

30

Responsible teacher

Lőrincz Márta

Teacher(s)

Szücs-Somlyó Éva, Gulyás Dominik

Prerequisites

Learning outcome (include skills and competencies, if any) Veterinary Immunology provides a summary of important knowledge for veterinarians. The subject is discussed in detail after the general introduction of the threefold structure of the immune system, focusing on the details of the elements of acquired immunity. Students will learn about immune prophylaxis, autoimmune diseases and various deficiencies or malfunctions of the immune system, knowledge that is essential in veterinary practice.

The laboratory exercises introduce the commonly used in vitro and in vivo diagnostic procedures, and also the mode of evaluation of the diagnostic results obtained through them.

Outcome assessment The first exam is written. There are 3 dates for written exams during an exam period (on the first, third and fifth weeks).

The written exam has two parts, a simple choice test and a figure analysis. Both parts has to be correct in at least 50% to have a successful exam. Re-take exams can be oral or written exams.

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Weekly schedule of lectures and practicals

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WEEK

Lecture topics

Week 1

Introduction to Veterinary Immunology

Week 2

Antigenes and Membrane-bound and Intracellular Receptors

Week 3

Phagocytosis and Antigen Presentation

Week 4

BCR and TCR

Week 5

T cells

Week 6

B cells

Week 7

Cellular and Humoral Immune Response

Week 8

Complement System and Inflammation

Week 9

The Regulation of the Immune Response

Week 10

General Overview of Immune Responses

Week 11

Immunodeficiency and Immune System of Birds

Week 12

Immune System of Fish and Bee

Week 13

Transplantation and Other Treatments for the Therapy of Immunological Diseases

Week 14

Consultation

WEEK

Practical topics

Week 1

Mucosal and Skin Immune Response

Week 2

Immune Response to Pathogens: Bacteria, Viruses and Fungi

Week 3

Immune Response to Pathogens: Parasites and Tumors

Week 4

Vaccination

Week 5

Foetal and Maternal Immunity

Week 6

Hypersensitivity Reactions

Week 7

Natural Autoimmunity, Immune-tolerance

Week 8

Autoimmune Diseases

Week 9

Immunodiagnostics, Serology, Agglutination

Week 10

Precipitation, Complement Fixation

Week 11

ELISA, Immunofluorescence, Immunohistochemistry

Week 12

PAGE, Western Blot, FACS, Rapid Diagnostic Methods

Week 13

Cellular and In Vivo Tests

Week 14

Holiday

SYLLABUS

VETERINARY PHARMACOLOGY 2 6th Semester Course description Course

Veterinary pharmacology 2

Department

Department of Pharmacology and Toxicology

Language

English

Nature

Mandatory

Year/semester

3rd year, spring-term

Credits (ECTS)

6

Lectures (hour/semester)

30

Plenary lectures (hour/semester) Practicals (hour/semester)

30

Responsible teacher

Dr. Ákos Jerzsele

Teacher(s)

Dr. Ákos Jerzsele, Dr. György Csikó, Dr. Orsolya Farkas, Dr. Erzsébet Gere, Dr. Zita Karancsi, Dr. Adrienn Mercédesz Veres, Dr. Dóra Kovács, Dr. Zoltán Somogyi

Prerequisites

Learning outcome (include skills and competencies, if any) After completion of the course the students will have: - solid background of pharmacology of antiseptics, disinfectants and concepts of antimicrobial agents, species-specific differences, antimicrobial resistance and thorough understanding of selection of certain antibiotics in various clinical settings - active knowledge of the pharmacology of the different classes of anthelmintic agents and the various factors which can influence the decision how to use a particular anthelmintic agent in veterinary practice - thorough information about the pharmacology of the different classes of antiprotozoal agents used in the control and/or treatment of coccidiosis and other protozoal diseases - most up-to-date theoretical and practical approaches for the ectoparasite control in different species - broad knowledge about anticancer, antifungal and antiviral drugs and their application possibilities and limitations in veterinary practice especially in the treatment of companion animals

Outcome assessment During the practicals, students have to be able to answer the questions about the topic of former and actual practical satisfactory either verbal or written (weekly test, quiz). Furthermore, the midterm tests will focus on the students’ acquired knowledge about the lectures’ material. On the final exam, students’ will have to present their knowledge about both semesters’ pharmacology studies.

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Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Introduction to chemotherapy

Week 2

Disinfectants and antiseptics

Week 3

Beta-lactam antibiotics

Week 4

Aminoglycoside antibiotics

Week 5

Tetracyclines. Macrolides

Week 6

Lincosamides, pleuromutilins. Phenicols

Week 7

Polypeptides, rifamycins, glycopeptides. Sulphonamides and diaminopyrimidines.

Week 8

Quinolones and other antibacterial agents

Week 9

Endoparasiticides I. Anticoccidials and other antiprotozoal drugs

Week 10

Endoparasiticides II. Anthelminthic agents (Antinematodal, antitrematodal and anticestodal drugs)

Week 11

Ectoparasiticides - Agents for external parasite control

Week 12

Antifungal drugs

Week 13

Antineoplastic and antiviral agents

Week 14

Introduction to veterinary drug development

WEEK

Practical topics

Week 1

Principles in fluid therapy

Week 2

Pharmacokinetic experiments with broiler chickens Basic knowledge of pharmacokinetics

Week 3

Pharmacology of inflammation

Week 4

Pharmacology of respiratory and cardiovascular system

Week 5

Pharmacology of hormones

Week 6

Reduction of antibiotic consumption in veterinary practice Disinfectants, antibiotic alternatives

Week 7

Test1 - Monday (Antibiotics) Theory and practice of PK/PD analysis General guidelines of prudent antimicrobial use

Week 8

Usage of antibiotics in companion animals

Week 9

Usage of antibiotics in ruminants and horses

Week 10

Holiday issued by the rector

Week 11

Usage of antibiotics in swine and poultry

Week 12

Test2 - Monday (Antiparasitics) Usage of anthelmintics

Week 13

Usage of ectoparasiticides

Week 14

Consultation, retake of missed or cancelled practicals

Recommended literature Handouts, notes and other files available on the home page.

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7TH SEMESTER

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INTERNAL MEDICINE 1 7th Semester Course description Course

Internal medicine 1

Department

Department and Clinic of Internal Medicine

Language

English

Nature

Mandatory

Year/semester

4th year, winter-term

Credits (ECTS)

4

Lectures (hour/semester)

45

Plenary lectures (hour/semester) 8 Practicals (hour/semester)

30

Responsible teacher

dr. Ferenc Manczur

Teacher(s)

dr. Ágnes Sterczer, dr. Ákos Máthé, dr. Csaba Hetyey, dr. Éva Balogh, dr. Ferenc Manczur, dr. Fruzsina Falus, dr. Károly Vörös, dr. Kinga Pápa, dr. Krisztina Kungl, dr. Márton Balogh, dr. Noémi Tarpataki, dr. Nóra Gulyás, dr. Péter Vajdovich, dr. Roland Psáder, dr. Zoltán Dudás Györki, dr. Zsuzsanna Vizi

Prerequisites

Learning outcome (include skills and competencies, if any) The goal of the subject is teaching of non-infectious diseases of the various organs and organ systems of the dogs and cats. Etiology and pathogenesis of these diseases are discussed in details as well as diagnosis, treatment and prevention. The subject includes both theoretical and practical education. The goal of the practical lessons of internal medicine is to practice diagnostic and therapeutic methods.

Outcome assessment Practical course grade Weekly schedule of lectures and practicals

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WEEK

Lecture topics

Week 1

Introduction to internal medicine. How to diagnose and treat diseases?

Clinical aspects of heart failure.

Week 2

Congenital cardiac diseases in dogs and cats. Acquired cardiac valvular diseases.

Week 3

Peroral, subcutaneous, intramuscular and intravenous drug application; microchip implantationniv. cannulation, blood transfusion.nReanimation, oxygen therapy.

Week 4

Fluid therapy, euthanasia. Myocardial diseases in dogs and cats. Clinical aspects of heartworm disease.

Week 5

Cardiac arrhythmias. Diseases of the pericardium.

Week 6

Upper respiratory diseases of the dog and cat (nasal cavity, larynx, trachea).

Methods of urine sampling: urinary catheterisation, cystocentesis. Rectal enema.

Week 7

Ultrasound-guided sampling methods: fine needle aspiration, biopsy; abdominocentesis, thoracocentesis, pericardiocentesis. Diseases of the thoracic cavity.

SYLLABUS

WEEK

Lecture topics

Week 8

Additional examination methods in dermatology. Treatment of the external ear canal.

Diseases of the lungs

Week 9

Diseases of the lungs. Respiratory signs in dogs and cats: respiratory or cardiac disease?

Week 10

Diseases of the digestive organs, dog and cat. Diseases of the oral cavity.

Week 11

Diseases of the oesophagus. Diseases of the stomach. Differential diagnosis of vomiting.

Week 12

Diseases of the small intestine.

Week 13

Diseases of the large intestines. Diagnostic work up of animals with diarrhoea.

Treatment of intestinal diseases.

Week 14

Diseases of the exocrine part of the pancreas.

Differential diagnosis of peritoneal and pleural fluid accumulation.

WEEK

Practical topics

Week 3

First visit at the veterinarian, examination of young animals, detection of congenital disorders/malformations; deworming, vaccination, microchip implantation.

Week 4 Week 5 Week 6 Week 7 Week 8 Week 9 Week 10 Week 11 Week 12

Peroral, subcutaneous, and intramuscular drug application.

Methods of reanimation. Gastric tubing, placement of enteral feeding tubes.

Method of blood sampling, cannulation and intravenous drug application.

Fluid therapy.

Urine sampling: urinary catheterisation, cystocentesis.

Abdominocentesis, thoracocentesis.”

Sampling methods in dermatology. Treatment of the external ear canal.

Recommended literature Obligatory book: Nelson, C.R., Couto, G.: Small Animal Internal Medicine. 5th ed. Mosby; St. Luis. 2014.

Suggested books: Feldman, S.R. et al.: Skin diseases of the dog and cat (2nd ed.) Blackwell Publishing, Iowa, 2005.

Yin, S.: The Small Animal Veterinary Nerdbook. 3.ed., Cattledog Publishing, Davis, 2010.

Plunkett, S.J.: Emergency Procedures for the Small Animal Veterinarian-, 3rd ed. Saunders, Elsevier, Edinburgh. Paperback –2013.

Lorenz, M.D. et al.: Small animal medical diagnosis. 3rd ed. Wiley-Blackwell, Ames. 2009.

Tilley, L.P.; Burtnick, N.: ECG for the small animal practitioner. Published by Teton New Media.

Teton NewMedia, Jackson, 2009.

Nyland, T. G.-Mattoon, J. S. Small animal diagnostic ultrasound. 3rd ed. W. B. Saunders, Philadelphia, 2015.

Penninck, D., d’Anjou, M-A.: Atlas of small animal ultrasonography, 2nd ed. Blackwell Publishing, Ames, 2015.

Ware, W. A.: Cardiovascular disease in small animal medicine. Manson Publishing Ltd. , London, 2007.

Ware, W. A.: Small animal cardiopulmonary medicine. Manson Publishing, London, 2011.

Ettinger, S.J.-Feldman E.C.-Cote, E. (eds.): Textbook of veterinary internal medicine. Diseases of the dog and cat. Expert consult, 8th ed., Saunders, St. Luis, 2017.

Greene, C.E.: Infectious diseases of the dog and cat. 4th ed. Elsevier, St. Luis, 2011.

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OBSTETRICS AND REPRODUCTION 1 7th Semester Course description Course

Obstetrics and reproduction 1

Department

Department of Obstetrics and Food Animal Medicine Clininc

Language

English

Nature

Mandatory

Year/semester

4th year, winter-term

Credits (ECTS)

6

Lectures (hour/semester)

45

Plenary lectures (hour/semester) Practicals (hour/semester)

45

Responsible teacher

Sándor CSEH, DVM, Ph.D., D.Sc., Professor

Teacher(s)

Laszlo SOLTI, DVM, Ph.D., D.Sc., member of the Hun. Academy of Science, Professor József RÁTKY, DVM, Ph.D., D.Sc., Professor Ottó SZENCI, DVM, Ph.D., D.Sc., Professor Emeritus András HORVÁTH, DVM, Ph.D. Zoltán SZELÉNYI, DVM, Ph.D. Lea LÉNÁRT, DVM, Ph.D.-student Anna CSEPREGHY, DVM, clinician Linda MÜLLER, DVM, Ph.D.-student, clinician Dóra KISPÁL, DVM, clinician Szilvia FARKAS, DVM, Ph.D., clinician Eszter SZILÁGYI, DVM, clinician Bence SOMOSKŐI, MSc., Ph.D., Research fellow

Prerequisites

Learning outcome (include skills and competencies, if any) The discipline is divided into the following main subjects: obstetrical aid and udder health (7th semester; Obstetric 1.), gynecology and reproductive care of different animal species (8th semester; Obstetrics 2.); andrology, assisted reproduction and biotechnology (9th semester, Obstetric 3). These subjects are covering the entire oestrous cycle, fertilization and pregnancy, parturition, puerperium and resumption of postpartal ovarian activity as well as reproductive management. Students can learn not only the theoretical aspects of neuroendocrine regulation of reproductiveprocesses but also the most frequently used operative techniques like Caesarean section, ovariohysterectomy, teat operation or vaginal prolapse. In addition to these traditional topics, assisted reproduction such as collection and cryopreservation of semen or embryos, artificial insemination and embryo transfer, in vitro fertilization, cloning and transgenic animals are also taught.

Outcome assessment 7th semester: semester-ending exam (mark offered based upon the result of the midterm tests or written exam)

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SYLLABUS

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

The introduction of the program and requirements. Introduction to physiology of reproduction I. Hypothalamus. Corpus pineale. Hypophysis. Ovarian structures (follicular development, ovulation, formation of corpus luteum).

Neurotransmitters, hormones, growth factors in animal reproduction (Solti, L.)

Week 2

Guest lecturer from the USA: Selected chapters of canine reproduction (presented by Bruce W. Chris-tensen;guided by S. Cseh)

Week 3

Introduction to physiology of reproduction II. Concept and comparative aspects of cyclic ovarian function in domestic mammals. Spontaneous and induced forms of ovulation. Seasonality of reproduction. Puberty. (Solti, L.)

Week 4

Introduction to physiology of reproduction III. Development and maturation of the oocyte. Fertilization. Early embryonic development. The concept and species-based characteristics of maternal recog-nition of pregnancy (Cseh, S.)

Week 5

Puberty. The cyclic ovarian function of the cow. Estrus. Estrus detection under farm conditions, and advanced techniques used to check and improve its efficacy. Physiology and pathology of pregnancy (embryonic and fetal development, development of fetal membranes, implantation endocrinology of pregnancy, pregnancy detection, termination of pregnancy; embryonic mortality; abortion) (Solti, L.)

Week 6

The ovarian function in postpartum dairy and beef cows (first ovulation / onset of cyclicity; first estrus; re-conception). Energy imbalance, and protein overfeeding, trace elements and other factors influenc-ing the postpartum reproduction.(Solti, L.)

Week 7

Physiology and care of calving. Neonatology (the care and non-infectionaldiseases of newborn calves). Injuries of the birth canal. The prolapsed uterus after calving.

Placental retention. (Cseh, S.

Week 8

Characteristics of uterine contractility during the early puerperium. Peri/postpartum metabolic disorders: milk fever, ketosis, and fatty liver disease. Udder oedema. (Cseh, S.)

Week 9

Physiology, pathology and clinical aspects of uterine involution and its bacterial complications. Principles of antimicrobial and prostaglandin therapy. (Földi, J.)

Week 10

Diseases and malfunctions of genitals (CLP; anovulatory cysts; delayed ovulation; tumors and other disorders; the contagious forms of subacute/chronic (endo)metritis; other inflammatory and non-inflammatory diseases/abnormalities of the oviduct, uterus, cervix and vagina). (Cseh, S.)

Week 11

Endocrine treatment procedures [estrus synchronization (gestagens, PGF2a); induction of ovarian cyclicity (gestagen+eCG, GnRH); induction of ovulation (GnRH); induction and synchronization of cyclicity / ovulation (Ov-synch=GPG) in dairy and beef cattle. Management of reproduction and infertility in (1) large-scale and (2) in smaller, family-operated dairy and beef herds (Cseh, S.)

Week 12

Anatomy, physiology and clinical investigation of the bovine udder; antimicrobial self-defense mechanisms of the udder; mastitis pathogens; pathogenesis of mastitis; inflammatory markers in the mastitis milk. Clinical pathology of mastitis caused by various pathogens (Staphylococcus aureus, CNS, Streptococci and Gram-negative environmental pathogens; the “summer mastitis”) (Jánosi Sz.)

Week 13

Principles in herd-level management of mastitis (Jánosi Sz.)

Week 14

Reproduction of small ruminants: Physiology of the oestrus cycle. Seasonality of reproduction. Induction and synchronization of the oestrus cycle. Methods for improving the ovulation rates. Pregnancy and its detection. Pathology of pregnancy, pregnancy toxemia / ketosis. Management of reproduction. (Cseh, S.)

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UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

WEEK

Practical topics

Week 1

Participants: Group 1., 2., 3., 4.

Subject: Education for work safety. The female genital tract in cattle: introduction and demonstration on organs from slaughterhouse. The technique for clinical examination of the genital tract. Rectovaginal technique of intracervical catheterisation (demonstration and practice)

Week 2

Participants: Group 5., 6., 7., 8.

Subject: Identical

Week 3

Participants: Group 1., 2., 3., 4.

Subject: Clinical examination of the genital tract incows. (practice) I.

Week 4

Participants: Group 5., 6., 7., 8.

Subject: Identical

Week 5

Participants: Group 1., 2., 3., 4.

Subject: Clinical examination of the genital tract incows. Recto-vaginal technique of intracervical catheterisation (practice) II.

Week 6

Participants: Group 5., 6., 7., 8.

Subject: Identical

Week 7

Participants: Group 1., 2., 3., 4.

Subject: Clinical examination of the genital tract in cows. Recto-vaginal technique of intracervical catheterisation (practice) III.

Week 8

Participants: Group 5., 6., 7., 8.

Subject: Identical

Week 9

Participants: Group 1., 2., 3., 4.

Subject: Epidural anaesthesia (demonstration on mare and cow, practice on cow).

Operative interventions on the bovine female genital tract (vaginal prolapse, episiotomy) (practice on organs from slaughterhouse)

Week 10

Participants: Group 5., 6., 7., 8.

Subject: Identical

Week 11

Participants: Group 1., 2., 3., 4.

Subject: Total foetotomy in mare and cow (introduction and practice)

Week 12

Participants: Group 5., 6., 7., 8.

Subject: Identical

Week 13

Retake

Week 14

Retake

Recommended literature D.E. Noakes, Timothy J. Parkinson and Gary C.W. England (eds):VeterinaryReproductionand Obstetrics. 9th edition, Saunders Elsevier, London, 2009 M.H. Pineda and Michael P. Dooly (eds): McDonald’s Veterinary Endocrinology and Reproduction. 5th edition, Iowa State Press A Blackwell Publishing Company, 2003.

R.S. Youngquist and Walter R.Threlfall (eds): Current Therapy in Large Animal Theriogenology.

2nd edition, Sounders Elsevier, St. Louis, Missouri, 2007.

E.C.Feldman, R.W. Nelson: Canine and feline Endocrinology andreproduction. 3rd edition, Saunders 2004.

P.L. Senger: Pathways to pregnancy and parturition 2nd edition, Pullman: Current Conceptions Inc. 2003. (3rd edition, 2011.)

M. Sandholm, T. Honkanen-Buzalski, L. Kaartinen, S. Pyörala: The bovine udder and mastitis. 1st edition, University of Helsinki, faculty of Veterinary Medicine, Helsinki, 1995.

Gary England, Angelika von Heimendahl: BSAVA Manual of Canine and Feline Reproduction and Neonatology. 2nd edition, British Small Animal Vererinary Association, Gloucester, 2010”

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PARASITOLOGY 2 7th Semester Course description Course

Parasitology 2

Department

Parasitology and Zoology

Language

English

Nature

Mandatory

Year/semester

4th year, winter-term

Credits (ECTS)

7

Lectures (hour/semester)

30

Plenary lectures (hour/semester) 0 Practicals (hour/semester)

30

Responsible teacher

Prof. Dr. Rรณbert Farkas

Teacher(s)

Prof. Dr. Rรณbert Farkas

Prerequisites

Learning outcome (include skills and competencies, if any) The principal theoretical and practical knowledge of the parasitic diseases of domestic animals caused by helminths.

Outcome assessment 150 multiple choice questions in computer exam + verbal exam

91

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Flatworms, fasciolosis, fascioloidosis

Week 2

Paramphistomatidosis, dicrocoeliosis, schistostomatidosis, Tapeworms, diphyllobothriosis

Week 3

Tapeworm infections of ruminants, carnivores, horse and poultry

Week 4

Larval cestodoses

Week 5

Hyostrongylosis, amidostomosis, ollulanosis, trichostrongylidosis

Week 6

Ancylostomatidosis, strongyloidosis, roundworm infections of carnivores

Week 7

Roundworm infections of horse, pig, ruminants and poultry. Heterakiosis

Week 8

Strongylidosis, strongylosis, larval cyathostominosis

Week 9

Oesophagostomosis, oxyuriosis, trichuriosis, chabertiosis, passalurosis

Week 10

Syngamosis. Lungworm infections of equines, ruminants and pig

Week 11

Lungworm infections of carnivores. Dirofilariosis

Week 12

Habronematidosis, spirocercosis, thelaziosis, parafilariosis, onchocercosis, setariosis

Week 13

Trichinellosis

Week 14

Trichuriosis, capillariosis, macracanthorchyncosis

WEEK

Practical topics

Week 1

Summarizing review of protozoa

Week 2

Summarizing review of arthropods

Week 3

Laboratory diagnoses of helminth infections. Life cycle of flukes and their intermediate hosts (T)

Week 4

Fasciolosis, dicrocoeliosis, paramphistomatidosis (T)

Week 5

Cestodoses (T)

Week 6

Larval cestodoses (T)

Week 7

Midterm examination

Week 8

Morphology and development of nematodes. Gastro-intestinal nematodes (ruminants, swine, goose) (T)

Week 9

Roundworm infections (T)

Week 10

Ancylostomatidosis, strongyloidosis, strongylidosis, strongylosis, cyathostominosis (T)

Week 11

Heterakiosis, oesophagostomosis, oxyuriosis, trichuriosis (T)

Week 12

Syngamosis, dictyocaulosis, protostrongylidosis, metastrongylidosis Lungworm infections of carnivores (T)

Week 13

Midterm examination

Week 14

Dirofilariosis, trichinellosis, capillariosis, macracanthorchyncosis

Recommended literature Peter Deplazes, Johannes Eckert, Alexander Mathis, Georg Samson-Himmelstjerna, Horst Zahner: Parasitology in Veterinary Medicine. 2016. Wageningen Academic Publishers

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SYLLABUS

PATHOLOGY C 7th Semester Course description Course

Pathology C

Department

Department of Pathology

Language

English

Nature

Mandatory

Year/semester

4th year, winter-term

Credits (ECTS)

3

Lectures (hour/semester)

15

Plenary lectures (hour/semester) Practicals (hour/semester)

45

Responsible teacher

Míra Mándoki

Teacher(s)

Míra Mándoki, Zoltán Német, Anna Szilasi, Péter Dobra

Prerequisites

Learning outcome (include skills and competencies, if any) Special pathology is discussing the pathologic background of diseases detailed, organized by organ systems. In this semester, special pathology of Avian species is lectured.

Outcome assessment On the practical exam the knowledge of dissection technique and practical related questions are evaluated. Separately, at the semi-final written exam, the questions asked are covering the theoretical part of the Avian special pathology presented during the 7th semester.

93

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Integumentary system, oro-pharyngeal cavity, oesophagus, crop, proventriculus, gizzard

Week 2

Small intestines

Week 3

Large intestines

Week 4

Liver

Week 5

Respiratory organs

Week 6

Serous body cavity. Heart and vessels

Week 7

Immunorgans (bone marrow, thymus, bursa, spleen)

Week 8

Locomotive organs 1.

Week 9

Locomotive organs 2.

Week 10

Urogenital organs

Week 11

Nervous system

Week 12

Multicentric tumors. Other diseases

Week 13

Written exam

Week 14

Re-take exam

WEEK

Practical topics

Week 1

Pathology of the broilers 1

Week 2

Pathology of the broilers 2

Week 3

Pathology of the eggs 1

Week 4

Pathology of the eggs 2

Week 5

Pathology of the newly hatched chicks 1

Week 6

Pathology of the newly hatched chicks 2

Week 7

Pathology of the layers 1

Week 8

Pathology of the layers 2

Week 9

Pathology of the water fowl 1

Week 10

Pathology of the water fowl 2

Week 11

Pathology of the turkeys 1

Week 12

Pathology of the turkeys 2

Week 13

Practical exam 1

Week 14

Practical exam 2

Recommended literature Lecture notes, Ferenc Vetési-Mihály Dobos-Kovács: Colour Atlas of Veterinary Pathology II., http://www.thepoultrysite.com/publications/6/Diseases_Of_Poultry (optional)

94

SYLLABUS

SURGERY 2 7th Semester Course description Course

Surgery 2

Department

Department and Clinic of Surgery and Ophthalmology

Language

English

Nature

Mandatory

Year/semester

4th year, winter-term

Credits (ECTS)

4

Lectures (hour/semester)

45

Plenary lectures (hour/semester) Practicals (hour/semester)

30

Responsible teacher

Tibor Németh, DVM, PhD, Dipl. ECVS, Professor

Teacher(s)

Tibor Németh DVM, Phd, Dipl. ECVS, Professor, Gábor Bodó DVM, DSc, Dipl. ECVS, Professor, Milós Pál Dunay DVM, PhD, Associate professor, Attila Arany-Tóth DVM, PhD, senior lecturer, Tamás Ipolyi DVM, senior clinician, Péter Molnár DVM, research fellow, Csilla Simon DVM, clinician, Dorottya Zólyomi DVM, research fellow, Zita Makra DVM, PhD, senior lecturer, Simon Izing DVM, senior clinician, Péter Tóth DVM, PhD, senior lecturer, Pál Tuska DVM, research fellow, Emese Bódai DVM, clinician

Prerequisites

Learning outcome (include skills and competencies, if any) surgical diagnostic skills (physical, orthopedic neurologic examination, colic, dental ) general surgical skills (wound management, bandages), basic operative surgical skills (scrubbing-in, incisions, suturing)

Outcome assessment Practical grade, based on lecture attendance and practical activity Weekly schedule of lectures and practicals

WEEK Week 1 Week 2 Week 3 Week 4 Week 5 Week 6 Week 7

Lecture topics Open injuries: classification, symptomes. Open injuries in particular tissues and organs. Wound healing. Regular and irregular wound healing Principles and methods of wound management. Necrosis, ulceration, fistulation Complicated wound healing, wound infection.

Surgical aspects of inflammation and anti-inflammatory therapy.

Closed mechanical injuries Surgical aspects of antibiotic therapy. Principles of small animal dentistry.

Principles of large animal dentistry Surgical aspects of circulatory shock. Emergency patient examination Fundamentals of operative surgery 95

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

WEEK

Lecture topics

Week 8 Week 9 Week 10 Week 11 Week 12 Week 13 Week 14

Surgery of the head and neck in small animals Surgery of the upper airways in small animals. Surgery of the thorax in small animals Surgery of the upper airways in horses. Surgery of hernias in small animals Colic-diagnostics. Abdominal surgery of the horse I. Abdominal surgery of the horse II. Abdominal surgery of the horse III. Hernias in horses. Small animal abdominal surgery. The laparotomy. Surgery of the stomach I. Surgery of the stomach II. Surgery of the small intestine. Surgery of the anorectum

WEEK

Practical topics

Week 1 Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8 Week 9 Week 10 Week 11 Week 12 Week 13 Week 14

Surgery of the oral cavity in horses Dentistry in horses Dentistry in horses; Lameness diagnostics in small animals Lameness diagnostics in small animals; Colic diagnostics Colic diagnostics; Neurological examination in small animals Neurological examination in small animals; Surgery of the head and neck in horses Surgery of the head and neck in horses; Wound management, bandaging in small animals Wound management, bandaging in small animals; Simple orthopaedic surgeries in horses Simple orthopaedic surgeries in horses; Emergency patient examination in small animals Emergency patient examination in small animals Operative surgery I. (wound preparation, suture materials, wound closure, types of sutures) Operative surgery I. (wound preparation, suture materials, wound closure, types of sutures) Operative surgery II. (wound preparation, suture materials, wound closure, types of sutures) Operative surgery II. (wound preparation, suture materials, wound closure, types of sutures)

Recommended literature Auer, J. A. Stick J: Equine surgery. 4th edition, Elsevier, Philadelphia, 2012.

Brinker, N. O. - Piermattei, D. L. - Flo, G. L.: Handbook of small animal orthopaedics and fracture treatment. 4th edition, Elsevier Saunders, 2006 Butler, J. A. ( et. al.) : Clinical radiology of the horse. 2nd edition, Blackwell Science, 2000 Donald, E. Thrall: Textbook of Veterinary Diagnostic Radiology. 6th edition, Elsevier, 2012 Hall, L.W. - Clarke, K. N.: Veterinary anaesthesiology. 9th edition, Wiley and Blackwell, 2008 McIlwraith, C. W. – Robertson J.T.: McIlwraith and Turner’s Equine surgery: advance techniques.

Wiley and Blackwell, 1998 Muir W . W. Hubbel, J. A. E. : Handbook of Veterinary Anesthesia. 5th edition, Elsevier Mosby, 2013 Permattei, D. L.: An atlas of surgical approaches the bones and joints of the dog and cat. Elsevier, 2013 Robinson, N. E.: Currrent therapy in equine medicine 7th edition. Philadelphia, Saunders 2015 Ross.M., Dyson, S.: Diagnosis and Management of Lameness in the horse. 2nd Ed. 2010.

Adam’s and Stashak’s Lameness in Horses. 6th edition, Wiley and Blackwell, 2011 Stashak, T. S.: Equine wound management. 2nd edition, Wiley and Blackwell, 2011.

Tobias KM – Johnston SA: Veterinary Surgery: Small Animal, Elsevier, 2012 Traub-Dargats, J. L - Brown, C. M.: Equine endoscopy. 2nd revised edition, Elsevier 1996

Note(s) Attendance of lectures and practical trainings is compulsory. The exam questions are based on topics of lectures and practical trainings. The attendance of lectures is checked 3 times a semester, the appearance of students at practical trainings is checked at every occasion. The prerequisite of obtaining the approval signature of the semester is the attendance of all practical trainings and at least 1 verified lecture-appearance per semester! Absence of lecture or practical training is regarded as verified in case of illness certified by physician or in case of official faculty programme (e.g. clinical shift). White coat is necessary for practical trainings.

96

SYLLABUS

TOXICOLOGY 7th Semester Course description Course

Toxicology

Department

Department of Pharmacology and Toxicology

Language

English

Nature

Mandatory

Year/semester

4th year, winter-term

Credits (ECTS)

3

Lectures (hour/semester)

30

Plenary lectures (hour/semester) Practicals (hour/semester)

0

Responsible teacher

Dr. Ákos Jerzsele

Teacher(s)

Dr. Ákos Jerzsele, Dr. György Csikó, Dr. Orsolya Farkas, Dr. Erzsébet Gere, Dr. Zita Karancsi, Dr. Adrienn Mercédesz Veres, Dr. Csaba Kővágó

Prerequisites

Learning outcome (include skills and competencies, if any) Upon completion of the course the students will have broad knowledge about: - common poisons such as mycotoxins, heavy metals, pesticides, poisons of animal- or herbal origin, toxic gases, drugs, ethylene glycol, feed and water associated-, industrial and household poisons - recognition of the clinical signs of intoxication - routes of exposure and disposition of different toxins in the body - sources of poisonings and possible therapeutic approaches for treatment, management of intoxicated patients such as application of supportive treatments and specific antidotes in case of animal toxicosis

Outcome assessment On the final exam, students’ will have to solve complex tasks about poisonings, focusing on the their clinically relevant aspects, such as diagnostic and treatment.

97

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Introduction to toxicology, sources of poisonings. Toxicokinetics, toxicodynamics.

Week 2

Factors influencing toxicity. Diagnosis and treatment of poisonings.

Week 3

Ethylene glycol poisoning.

Week 4

Pesticides II. Insecticides, molluskicides

Week 5

Pesticides I. Rodenticides

Week 6

Drug poisonings

Week 7

Pesticides III. Herbicides, fungicides

Week 8

Metal poisonings I. Mercury, lead, arsenic, selenium, iron, copper, zinc

Week 9

Feed and water associated poisonings (NaCl, urea, nitrate-nitrite, ionophores)

Week 10

Industrial toxicoses (cadmium, fluoride, PCB-s, dioxins) Household poisonings: acids, alkali, detergents, parfumes

Week 11

Toxic gases

Week 12

Toxicology of mycotoxins

Week 13

Plant poisonings

Week 14

Poisonings of animal origin

Recommended literature Handouts, notes and other files available on the home page.

98

SYLLABUS

8TH SEMESTER

99

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

ANIMAL HYGIENE AND HERD HEALTH 1 8th Semester Course description Course

Animal hygiene and herd health 1

Department

Department of Animal Hygiene, Herd Health and Mobile Clinic

Language

English

Nature

Mandatory

Year/semester

4th year, spring-term

Credits (ECTS)

1

Lectures (hour/semester)

30

Plenary lectures (hour/semester) Practicals (hour/semester)

farm animal herd health practical, one day farmvisit

Responsible teacher

Dr. habil. László Könyves, PhD, assoc. professor

Teacher(s)

Prof. Dr. Endre Brydl CSc, Dr. Viktor Jurkovich PhD, Dr. Péter Kovács DVM, Dr. László Könyves PhD, Péter Hejel, Dr. Csaba Pribenszky PhD

Prerequisites

Learning outcome (include skills and competencies, if any) Animal Hygiene is the branch of the veterinary science, which relying on knowledge of physiological and ethological demands of animals, describes the preconditions of health preservation and investigates the pathophysiological changes brought about by adverse environmental effects in order to gain information on the aetiology and pathomechanism of multifactorial diseases. On this basis, animal hygiene systematise the preventive veterinary measures with special reference to their economic consequences. Animal hygiene deals primarily with herds and health protection of the herds, therefore the subject is more or less equivalent to the subject „herd health” taught in number of the veterinary colleges of the western hemisphere.

Animal hygiene is an interdisciplinary science that lay bridge over animal husbandry and veterinary medicine. Its curriculum involves the management and nutrition technologies of farm animals. The discipline also describes the multilateral effects of housing and nutrition on the health, on the inherited behavioural characteristics of farm and companion animals, on economy of their production and on the rural environment. Based on these knowledge vet¬erinary undergraduates will be trained to become able for critical analysis of housing systems and nutritional regimes, for understanding the aetiology of management related diseases prevailing at herd level, for the application of methods of herd health management in order to prevent and control of multi¬factorial diseases of high economic consequences.

Beyond teaching theoretical and practical knowledge of the discipline we endeavour to implement three goals. First of all we try to form an approach by which the veterinary practitioner becomes able to analyse the production decline, abnormal behaviour and animal diseases in their complex interactions with the environment. We also intend to prepare our undergraduates for the analysis of the economic consequences of their preventive and curative meas¬ures. And last but not least in harmony with other disciplines we regard important to teach our students to esteem and acknowledge the work of experts of other branch of agricultural science.

Theoretical and practical knowledge of animal hygiene is based on animal physiology, husbandry, nutrition, microbiology and immunology. At the same time it contributes to the better understanding of epizootology, state vet¬erinary medicine and food inspection.

Outcome assessment Three level evaluation (“Excellent”; “Accepted” or “Not Accepted”) on the basis of the activity and preparedness of the students on farmvisits.

100

SYLLABUS

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Introduction of the subject „Animal Hygiene and Herd Health”. Dairy farm visit. General aspects, preparation and execution. Visual herd diagnostic (scoring) methods. Examination of the feeds and ration. Evaluation of the housing and the management.

Week 2

Week 3 Week 4 Week 5 Week 6 Week 7 Week 8

Week 9

Week 10 Week 11

Week 12

Week 13 Week 14

Epidemiological aspects of establishing and operating animal production units. Bio-security measures. Animal hygienic principles of construction and reconstruction of stables. Physical properties of building materials. Demands for walls, roof, windows and floor. Canalization of stables Disinfection of stables and animal premises. Definitions. Factors affecting efficiency of disinfection.

Physical and chemical methods of disinfection. Practical disinfection of stables, hatcheries, persons, vehicles, watering systems, water resources. Disinfection of milking operation units. Checking the efficiency of disinfection.

Environmental effects of animal farming. Sustainability of livestock production, environmental impacts of emissions. Categories, disposal and processing of animal wastes Interactions between animal and its surrounding. Research and latest results in stress concept.

Feed hygiene I. Mycotoxins. General characteristics of mycotoxins. Classification of moulds. Field fungi. Fusarium toxins. Zearalenone. Trychothecenes. Fumonisins. Satratoxins.

Feed hygiene II. Hygiene of the drinking water.

Rules and good execution practice of collecting feed and water samples for analysis.

Feed hygiene III. Animal hygieneic aspects of the chemical decomposition of feed components. The oxidative stress. Biogen amines. Preventive measures Microbial contamination of feeds. Classification of feed flora, Environmental conditions of microbial gradation. Consequences of feed spoilage and preventive measures The effect of microclimatic conditions on the production and health of the farm animals. Energy metabolism of the organism. Thermal balance of animals. Heat exchange between organism and environment. Thermoregulation of the animals. Effect of environmental factors on energy metabolism of farm animals. Adaptation to climatic conditions The effect of heat stress on the health and performance of farm animals. Quantification of heat stress.

Effects of aerial pollutions on production and health of farm animals. Gaseous contaminants of the stable air. Biological aerosols. Measurement methods of airborne pollutants.

Climatization of stables. Ventilation of stables. Heat supply to stables. Measurement of the climatic surrounding. Interpretation and measurement of the physical elements of the microclimatic conditions. Technical equipments of the climatic measurements. Data processing.

Management related (sin. multifactorial) diseases of farm animals. Definitions: multifactorial diseases; germ load; facultative pathogens. Defence mechanisms. Interactions between housingmanagement factors and germ load. Interactions between housing-management factors and the defence mechanisms. Principles of control of the management related diseases.

Feed hygiene IV. Store-house moulds. Aflatoxins, Ochratoxins, Patulin, Citrinin, Mycotoxin contamination of feed commodities. Relevant regulations. Defence against mycotoxin contamination.

Precision livestock farming (PLF), as a new tool of the modern animal husbandry and herd-health management. Benefits and practical use of the automated, real time monitoring systems.

Recommended literature BRAND A. - NORDUIZEN J.P.T.M. – SCHUKKEN Y.H.: Herd Health and Production Management in Dairy Practice. Wageningen: Wageningen Pers, 1996.

RADOSTITS O.M.: Herd Health Food Animal Production Medicine. W.B. Saunders Company, 2001.

EKESBO, I. 2011. Farm animal behaviour, CABI, Wallingford, UK, ISBN: 9781845937706Jensen, P. 2009. The ethology of domestic animals, CABI, Wallingford, UK, ISBN: 9781845935368 ALAND, A. - BANHAZI, T. (ed.) Livestock housing. Modern management to ensure optimal health and welfare of farm animals ISBN: 978-90-8686-217-7

Note(s) Attendance of the theoretical lectures is suggested because the curriculum is subjected to continuous up-dating. The attendance of the farmvisit is compulsory according to the official schedule.

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UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

AVIAN AND EXOTIC ANIMAL MEDICINE 8th Semester Course description Course

Avian and exotic animal medicine

Department Language

English

Nature

Mandatory

Year/semester

4th year, spring-term

Credits (ECTS)

2

Lectures (hour/semester)

24

Plenary lectures (hour/semester) Practicals (hour/semester)

0

Responsible teacher

János Gál

Teacher(s)

János Gál, Anikó Mózer, Antal Papp, Anna Nógrádi

Prerequisites

Learning outcome (include skills and competencies, if any) The students are studying about the infection and non-infection diseases of exotic animals. It is useful in the future work in the small animal practice.

Outcome assessment Test exam Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Biology and keeping of exotic reptiles and birds.

Week 2

Non-infectious and infectious diseases of reptiles I.

Week 3

Non-infectious and infectious diseases of reptiles II.

Week 4

Non-infectious and infectious diseases of birds I.

Week 5

Non-infectious and infectious diseases of birds II.

Week 6

Anesthesia of exotic animals.

Week 7

Surgery of exotic animals.

Week 8

Biology and keeping of exotic rodents.

Week 9

Biology and keeping of ferrets.

Week 10

Non-infectious and infectious diseases of rodents I.

Week 11

Non-infectious and infectious diseases of rodents II.

Week 12

Non-infectious and infectious diseases of ferrets.

Recommended literature Slides of lectures 102

SYLLABUS

BEE HYGIENE AND HEALTH 8th Semester Course description Course

Bee hygiene and health

Department

Parasitology and Zoology

Language

English

Nature

Mandatory

Year/semester

4th year, spring-term

Credits (ECTS)

2

Lectures (hour/semester)

12

Plenary lectures (hour/semester) 0 Practicals (hour/semester)

0

Responsible teacher

Prof. Dr. Rรณbert Farkas

Teacher(s)

Prof. Dr. Rรณbert Farkas

Prerequisites

Learning outcome (include skills and competencies, if any) The knowledge of the subject allow veterinarians participate with beekeepers and apiary technicians in prophylaxis of colony health disorders. food hygiene of these food producing animals and managing notifiable bee diseases.

Outcome assessment Multiple choice questions in written exam Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Introduction, morphology and life cycle of honey bees

Week 2

Life of honey bees

Week 3

Beekeeping

Week 4

Viral infections

Week 5

American foulbrood

Week 6

European foolbrood. Other bacterial infections

Week 7

Infections caused by fungi (chalk-brood, stone-brood)

Week 8

Nosemosis

Week 9

Acaparis woodi. Varroa destructor and other mites

Week 10

Predators of honey bees. Insecticide toxicity

Week 11

Non-infectious disorders, the control of bee diseases

Week 12

Legislation in bee diseases, consultation

Recommended literature Roger a Morse and Kim Flottum: Honey Bee Pests, Predators, and Diseases 3rd Edition 103

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

FISH HYGIENE AND DISEASES 8th Semester Course description Course Department Language Nature Year/semester Credits (ECTS) Lectures (hour/semester) Plenary lectures (hour/semester) Practicals (hour/semester) Responsible teacher

Fish hygiene and diseases Department of Exotic Animal and Wildlife Medicine English Mandatory 4th year, spring-term 2 30 0 Dr. Ferenc BASKA

Learning outcome (include skills and competencies, if any) The aim of the training course on fish pathology is to introduce the students into the modern knowledges both in the infective fish diseases and environmentally and farming technologically influenced health condition of fishes. After a brief introduction into the anatomy and physiology of farmed fishes (mostly carp fishes and salmonids) detailed informations on infective (viral, bacterial, fungal, parasitological) and non-infective diseases and intoxications are going to provided.

Outcome assessment Written semifinal exam Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1 Week 2 Week 3

The structure of the fish. The integument. Taxonomic features.

The motion. The digestive system. Digestion.

Gills and respiration. Blood and vascular system.

Urinary system, excretion. Gonads and reproduction. Endocrin system. Nervous system. Sensory organs.

Water environment and it’s characteristics. The food-chain. Fish pond and fish farm.

Technical characteristics and function of the fishing establishment.

Fish culture technology and it’s effect on fish. Spawning, rearing, harvesting, wintering, transporting.

On the spot examination of fish and pond. Requirements towards specimens for laboratory examination Diseases caused by viruses. SVC, VHS, IPN. Bacterial diseases. Erythrodermatitis, vibriosis.

Diseases caused by algae and moulds. Gill necrosis, saprolegniasis, toxicosis caused by algae.

Importance of parasitic infection. Diseases caused by protozoan parasites. White spot disease. Diseases caused by sporozoan parasites. Coccidiosis, Swimbaldder-inflammation.

Diseases caused by metazoan parasites. Gill worms, helmints, blood-sucker parasites.

Diseases caused by environmental factors. Loss of oxygen, feeding disorders.

Treatment and medication in the fish farming praxis.

Toxicosis of fish. Heavy metal, insecticide and other toxicosis.

Regulations in the EC, veterinary controll.

Week 4 Week 5 Week 6 Week 7 Week 8 Week 9 Week 10 Week 11 Week 12 Week 13 Week 14

Recommended literature

Baska, F (2013): Lecture ppt files, Molnár, K., Szakolczay, J. (1997): Fish hygiene. Egyetemi Jegyzet.

Szent István Egyetem, Állatorvos-tudományi Kar, Kórbonctani és Igazságügyi Állatorvostani Tanszék, Roberts, R.J. (2000) Fish Pathology 104

SYLLABUS

INTERNAL MEDICINE 2 8th Semester Course description Course

Internal medicine 2

Department

Department and Clinic of Equine Medicine

Language

English

Nature

Mandatory

Year/semester

4th year, spring-term

Credits (ECTS)

3

Lectures (hour/semester)

60

Plenary lectures (hour/semester) 0 Practicals (hour/semester)

45

Responsible teacher

Zoltan Bakos

Teacher(s)

Zoltan Bakos, Imre Biksi, András Horváth, Péter Mikó, Zoltán Szelényi, Tamás Abonyi, Csaba Földvári-Nagy

Prerequisites

Learning outcome (include skills and competencies, if any) The course will attempt to assist students in acquiring sufficient up-to-date knowledge of the most common and important internal diseases of swine, ruminants and horses. This will be done via the use of didactic lectures and practical sessions. The breadth of information in large animal internal medicine is vast, therefore students are also expected to do additional self-directed reading around the topics presented. The course also stimulates students to apply the knowledge learned, to analysis and problem-solving situations that will likely be encountered during practical classes, one-week clinical practicals, 11th semester rotations and later in large animal practice. Students will be presented with various large animal diseases/medical concepts and are expected to have a good knowledge of the associated aetiology, pathogenesis and/or pathophysiology, clinical signs, epidemiology (where applicable), methods of diagnosis, treatment options, prevention/control and prognosis. Students should be able to formulate a list of differential diagnoses for each disease presented. Students will be expected to know the indications, forms, routes and potential adverse reactions for selected drugs commonly used in large animal therapy.

Outcome assessment Practical course grade. Calculated as the mean of written test results completed during the large animal practical sessions.

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Weekly schedule of lectures and practicals

WEEK Week 1 Week 2 Week 3

Lecture topics Gastric ulcer, enteritis, impaction in swine. Diseases of the liver in swine. Cardiac and haematopoietic diseases in swine.

Diseases of the nervous system and the skin in swine. Diseases of the oral cavity in ruminants. diseases of the liver in ruminants.

Diseases of the oesophagus, classification of forestomach disorders in ruminants.

Rumen acidosis, ruminal bloat.

Week 4

Reticuloperitonitis, vagus indigestion. Abomasal diseases. Abomasal reflux syndrome.

Week 5

Diseases of the intestines in ruminants. Respiratory diseases in ruminants.

Week 6

Metabolic and locomotion diseases; haematopoietic diseases; cardiac diseases in ruminants.

Week 7

Urinary diseases; diseases of the skin; diseases of the nervous system in ruminants.

Week 8

Diseases of the oral cavity and oesophagus in horses. General features of colic diseases. Gastric diseases in horses. Spasmodic colic, acute enteritis in horses.

Week 9

Impaction of the large intestine in horses. Types and clinical aspects of ileus in horses.

Week 10

Impaction of the large intestine in horses. Types and clinical aspects of ileus in horses.

Week 11

Chronic enteritis. Diseases of the liver. Upper airway diseases in horses.

Week 12

Diseases of the guttural pouch. Equine asthma. Lower airway diseases in horses.

Week 13

Cardiovascular diseases; haematopoietic diseases; urinary tract diseases in horses.

Week 14

Endocrine and metabolic diseases; diseases of the nervous system; diseases of the skin in horses

WEEK

Practical topics

Week 1 Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8 Week 9 Week 10 Week 11 Week 12

Oral and parenteral drug administration in horses. Blood collection, intravenous catheterisation, blood culture, arterial and venous blood gas analysis, blood transfusion.

Intravenous crystalloid and colloid therapy in horses.

Oral rehydration. Infectious disease control and prevention Nasogastric intubation, gastric lavage, caecal trocarisation, transrectal colon puncture, rectal enema in horses. Sampling methods from the alimentary tract.

Abdominocentesis and thoracocentesis in horses.

Urine collection and urinalysis.

Collection of tracheal wash and bronchoalveolar lavage samples.

Muscle biopsy and its indications.

Skin scraping and skin biopsy. Collection and interpretation of cerebrospinal fluid samples Oral and parenteral drug administration in ruminants.

Blood collection, intravenous catheter placement, blood culture, arterial and venous blood gas analysis, blood transfusion.

Intravenous crystalloid and colloid therapy in ruminants. Oral rehydration Orogastric tubing, trocarisation of the rumen. Abdominocentesis and thoracocentesis in ruminants. Examination of the rumen fluid. Other sampling methods from the alimentary tract.

Making up of missed practical sessions.

Recommended literature Constable, P.D. et al. (eds): Veterinary Medicine. A textbook of the diseases of cattle, horses, sheep, pigs and goats. 11th ed., Saunders, St. Luis, 2016.

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SYLLABUS

LABORATORY ANIMAL SCIENCE AND BIOETHICS 8th Semester Course description Course

Laboratory animal science and bioethics

Department Language

English

Nature

Mandatory

Year/semester

4th year, spring-term

Credits (ECTS)

2

Lectures (hour/semester)

15

Plenary lectures (hour/semester) 8 Practicals (hour/semester) Responsible teacher

Prof. Dr. Sándor György Fekete

Teacher(s)

Dr. András Bersényi, Dr. Gabriella Korsós

Prerequisites

Learning outcome (include skills and competencies, if any) Basic knowledge about the zoology, behaviour, feeding and diseases of the laboratory animals.

Pain and stress recognition and alleviation. Bioethical aspects of animal experimentation. How to write a bioethical assay. Handling of laboratory animals, application of grimace score, simple experimental techniques.

Outcome assessment Personally to write a biothical assay; multiple-choice test, mini-assay / oral exam

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UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Generally about the experimental models. Questions of scientific philosophy.

Week 2

Taxonomy, biology and applied physiology of laboratory animals I.: Herbivorous and omnivorous species, incl. non-vertebrates.

Week 3

Taxonomy, biology and applied physiology of laboratory animals II.: Carnivorous species, incl. non-vertebrates.

Week 4

Alternatives to animal experimentation. The 3(4) Rs principles.

Week 5

Genetic standardisation. Speciality of transgenic animals. Control of genetic quality.

Week 6

Microbiological standardisation; the most important zoonoses.

Week 7

Requirements to environment: keeping, husbandry and hygienic levels of animal facilities and animals.

Week 8

The experimental design. Organisation and management of animal trials.

Week 9

Important animal models in basic research (e.g. Caenorhabditis elegans, Drosophila melanogaster)

Week 10

Important animal models in applied research (e.g. ob/ob, nu/nu, SCID, RAG-mouse)

Week 11

Important animal models in plurigenomics (e.g. Nutri- and epigenomics, milk composition, anticancerogenic effect, ageing)

Week 12

Well-being of laboratory animals, discomfort, stress. Recognition, prevention and alleviation of pain and suffering. Environmental enrichment. Pain categories.

Week 13

Theoretical basics of bioethics. Utilitarism, neo-kantism and the animal rights.

Ethical aspects of animal experimentation.

Week 14

Animal trials and animal protection. Authorisation of the animal trials and projects.

WEEK

Practical topics

Week 1

Basics of the anatomy of the laboratory animals (mouse, rat, guinea-pig, rabbit)

Week 2

Description, breedoing and feeding of laboratory animals.

I. Herbivorous and omnivorousspecies (mouse, rat, rabbit, minipig, poultry etc.)

II. Carnivorous species (ferret, cat, dog)

Week 3

Genetic calculations and examples.

Week 4

Practical laboratory animal husbandry: buildings, equipments, cages, feeders and drinkers, solid water, beddings; tools ofenvironmental enrichment.

Week 5

Handling and simple experimental techniques (mouse, rat, golden hamster, guineapig, rabbit, poultry)

Week 6

Diagnostic necropsy of laboratory animals (mostly rodents)

Week 7

Discussion about the justification of living animal experimentation versus in vitro.

Week 8

The 3Rs in analgesia, anaethesia and humane euthanasia. Cost-benefit analysis, nonprofessional summary.

Recommended literature Van Zutphen, LFM.-Bauman, V.-Beynen, AC: Priciples of Laboratory Animal Science. Elsevir.

Amsterdam, 1993, 2000.; NRC: Nutrient requirements of laboratory rodents. Washington, 1986; Svedsen, P.-Hau, J. (eds): Handbook of Laboratory Animal Science. CRS Press. Boca Raton, Fla, 1994, 2004; Regan, T.: The case of animal rights. Univ. Calif. Press. Berkeley, Los Angeles, 1983; Fekete, SGy: Feeding and Nutrition of the Laboratory Rabbit. In: DeBlas, C-Wiseman, J.: The Nutrition of the Rabbit. CABI Publ. Oxon-New York, 2019 108

SYLLABUS

OBSTETRICS AND REPRODUCTION 2 8th Semester Course description Course

Obstetrics and reproduction 2

Department Language

English

Nature

Mandatory

Year/semester

4th year, spring-term

Credits (ECTS)

3

Lectures (hour/semester)

45

Plenary lectures (hour/semester) Practicals (hour/semester)

45

Responsible teacher

Sándor CSEH, DVM, Ph.D., D.Sc., Professor

Teacher(s)

Laszlo SOLTI, DVM, Ph.D., D.Sc., member of the Hun. Academy of Science, Professor József RÁTKY, DVM, Ph.D., D.Sc., Professor Ottó SZENCI, DVM, Ph.D., D.Sc., Professor Emeritus András HORVÁTH, DVM, Ph.D. Zoltán SZELÉNYI, DVM, Ph.D. Lea LÉNÁRT, DVM, Ph.D.-student Anna CSEPREGHY, DVM, clinician Linda MÜLLER, DVM, Ph.D.-student, clinician Dóra KISPÁL, DVM, clinician Szilvia FARKAS, DVM, Ph.D., clinician Eszter SZILÁGYI, DVM, clinician Bence SOMOSKŐI, MSc., Ph.D., Research fellow

Prerequisites

Outcome assessment 8th semester: practical grade (mark offered based upon the result of the midterm tests or written exam) Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Canine reproduction 1.

Physiology of the oestrus cycle. Physiology and pathology of puberty. Estrus.

Canine pregnancy and pseudopregnancy. (L.Müller)

Week 2

Canine reproduction 2. Parturition and involution. Cesarian section, clinical care of mother and neonatology in canine. Peripartal diseases. (L. Müller)

Week 3

Canine reproduction 3.

Cystic endometrial hyperplasia (CEH/HGCE) – pyometra complex and its extragenital consequences. Symptoms and treatment.

Feline reproduction. Physiology of the oestrus cycle. Estrus. Puberty.

Pregnancy and pseudopregnancy. Parturition and involution. (L. Müller)

Week 4

Canine reproduction 4.

Abnormalities of the oestrus cycle. Pharmacological treatments influencing the oestrus cycle. Diagnosis and treatment of mastitis, benign and malignant mammary diseases. (L. Müller) 109

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

110

WEEK

Lecture topics

Week 5

The effects, timing and technique of spaying/neutering small animals. (L. Müller)

Week 6

Equine reproduction 1.

Physiology of the oestrus cycle. The heat. The seasonality of the oestrus cycle.

Possibilities and limitations of inducing the first ovulation in the beginning of the breeding season. Oestrus synchronisation in the breeding season.(L. Solti)

Week 7

Equine reproduction 2.

Genital disorders and infertility in horses: Ovarian disorders with changes in size (haematoma, abscess, and tumor). Ovarian disorders with no changes in size (shortening of the CL-phase, dioestral ovulation, corpus luteum persistency, and nymphomania). (L. Solti)

Week 8

Equine reproduction 3.

Causes and differential diagnosis of anoestrus in the breeding season.

Pathology, symptoms, diagnosis and treatment of endometritis and endometriosis.

Fibrosis periglandularis. (L. Solti)

Week 9

Equine reproduction 4.

Equine pregnancy: Characteristics of embryonic and foetal development. The endocrinology of the pregnancy. Diagnosis of the pregnancy. Embryonic mortality and abortion.

Twin pregnancy and its management. Abortions of different causes. (A. Horváth)

Week 10

Equine reproduction 5.

Equine obstetrics: Displacement of the pregnant uterus. Predicting the time of the parturition. The foaling and its supervision. Caring for the newborn foal.

Placental retention. The equine puerperium. Injuries of the reproductive tract.

Onset of cyclic ovarian function after foaling. The foal heat. (A. Horváth)

Week 11

Porcine reproduction 1.

Physiology of the oestrus cycle, puberty, onset of cyclic ovarian activity after weaning.

The remnants of seasonality and its practical aspects. Oestrus and oestrus detection.

Induction of oestrus. Possibilities and limitations of synchronization. (J. Rátky)

Week 12

Porcine reproduction 2.

Fertilization. Early embryonic development. Endometritis after artificial insemination, as a main cause of infertility. Herd-level management of reproduction. (J. Rátky)

Week 13

Porcine reproduction 3.

Porcine pregnancy and parturition: Physiology, pathology and diagnosis of pregnancy.

Farrowing. The involution of the sow. Caring for the piglets and their main diseases.

Nutritional and environmental factors influencing the reproduction. (J. Rátky)

Week 14

Guest lecturer (guided by S. Cseh)

WEEK

Practical topics

Week 1

Participants: Group 1, 2, 3, 4.

Subject: Vasectomy and penis-translocation of the teasing ram (A. Horváth, L. Lénárt, Z. Szelényi, A. Csepreghy)

Week 2

Participants: Group. 5,6, 7, 8.

Subject: Identical (A. Horváth, L. Lénárt, Z. Szelényi, A. Csepreghy)

Week 3

Participants: Group 1, 2, 3, 4.

Subject: Caesarean section in cow (practice of the surgery on animals bought for this purpose) (A. Horváth, L. Lénárt, Z. Szelényi, A. Csepreghy)

Week 4

Participants: Group 5, 6, 7, 8.

Subject: The same, as for the other half of the class one week earlier (A. Horváth, L. Lénárt, Z. Szelényi, A. Csepreghy)

SYLLABUS

WEEK

Practical topics

Week 5

Participants: Group 1, 2, 3, 4.

Subject: Diagnostic methods and treatment procedures during the uterine involution in cattle (demonstration and practice in cows C-sectioned one and two weeks earlier). Preparations widely used for treatment of bacterial complications in uterine involution (A. Horváth, L. Lénárt, Z. Szelényi, A. Csepreghy)

Week 6

Participants: Group 5, 6, 7, 8.

Subject: The same, as for the other half of the class one week earlier (A. Horváth, L. Lénárt, Z. Szelényi, A. Csepreghy)

Week 7

Participants: Group 1, 2, 3, 4.

Subject: Caesarean section in sows (practice of the surgery on animals bought for this purpose) (A. Horváth, L. Lénárt, Z. Szelényi, A. Csepreghy)

Week 8

Participants: Group 5, 6, 7, 8.

Subject: The same, as for the other half of the class one week earlier (A. Horváth, L. Lénárt, Z. Szelényi, A. Csepreghy)

Week 9

Participants: Group 1, 2, 3, 4.

Subject: Diagnostic methods and treatments in management of equine reproduction (rectal and ultrasound examination of the ovaries andthe uterus, lavage of the uterus, collection of samples for bacteriology, cytology and histology, examination of the cervical smear and the histology of bioptic samples from the endometrium) (A. Horváth, L. Lénárt, Z. Szelényi, A. Csepreghy)

Week 10

Participants: Group 5, 6, 7, 8.

Subject: The same, as for the other half of the class one week earlier (A. Horváth, L. Lénárt, Z. Szelényi, A. Csepreghy)

Week 11

Participants: Group 1, 2, 3, 4.

Subject: Operative interventions on the bovine udder (injuries and fistulas of the teat and the glandular part of the udder) (practice).

Artificial drying-off. Aseptic technique of taking milk samples for bacteriology. Rapid cow side tests used for detection of subclinical mastitis.

The most important preparations used in management of mastitis (A. Horváth, L. Lénárt, Z. Szelényi, A. Csepreghy)

Week 12

Participants: Group 5, 6, 7, 8.

Subject: The same, as for the other half of the class one week earlier (A. Horváth, L. Lénárt, Z. Szelényi, A. Csepreghy)

Week 13

Retake

Week 14

Retake

Recommended literature D.E. Noakes, Timothy J. Parkinson and Gary C.W. England (eds):VeterinaryReproductionand Obstetrics. 9th edition, Saunders Elsevier, London, 2009 M.H. Pineda and Michael P. Dooly (eds): McDonald’s Veterinary Endocrinology and Reproduction. 5th edition, Iowa State Press A Blackwell Publishing Company, 2003.

R.S. Youngquist and Walter R.Threlfall (eds): Current Therapy in Large Animal Theriogenology.

2nd edition, Sounders Elsevier, St. Louis, Missouri, 2007.

E.C.Feldman, R.W. Nelson: Canine and feline Endocrinology andreproduction.3rd edition, Saunders 2004.

P.L. Senger: Pathways to pregnancy and parturition 2nd edition, Pullman: Current Conceptions Inc. 2003. (3rd edition, 2011.)

M. Sandholm, T. Honkanen-Buzalski, L. Kaartinen, S. Pyörala: The bovine udder and mastitis. 1st edition, University of Helsinki, faculty of Veterinary Medicine, Helsinki, 1995.

Gary England, Angelika von Heimendahl: BSAVA Manual of Canine and Feline Reproduction and Neonatology. 2nd edition, British Small Animal Vererinary Association, Gloucester, 2010

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PATHOLOGY D 8th Semester Course description Course Department Language Nature Year/semester Credits (ECTS) Lectures (hour/semester) Plenary lectures (hour/semester) Practicals (hour/semester) Responsible teacher Teacher(s)

Pathology D Department of Pathology English Mandatory 4th year, spring-term 6 30 60 Míra Mándoki Míra Mándoki, Gyula Balka, Imre Biksi, Anna Szilasi, Péter Dobra, Ervin Albert, Német Zoltán

Prerequisites

Learning outcome (include skills and competencies, if any) Special pathology is discussing the pathologic background of diseases detailed, organized by organ systems, emphasizing the differences between species. In this semester, the second half of the Mammalian special pathology is lectured. Every first week students have histopathology practicals at István street campus, and every second week large animal pathology practicals at Üllő.

Outcome assessment The 8th semester closes with the final exam in special pathology. The exam consists of 3 parts. We check the knowledge of the students in dissection, histopathology and the theoretical knowledge (Pathology B, D). The final (5-scale) grade will be evaluated based on the performance during the whole exam. After this exam, students are well-prepared for further studies (eg. Epidemiology, Food Hygiene, State Veterinary Medicine) and for being a responsible veterinarian after graduation.

Weekly schedule of lectures and practicals

112

WEEK

Lecture topics

Week 1 Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8 Week 9 Week 10 Week 11 Week 12 Week 13 Week 14

Pathology of the heart Pathology of the arteries, serous membranes, spleen Pathology of the spleen, bone marrow, lymph nodes Pathology of the airways Pathology of the lungs 1.

Pathology of the lungs 2.

Pathology of the kidneys Pathology of the kidneys and lower urinary tract Pathology of the genital organs Pathology of the placenta and the fetus Pathology of the bones, joints, muscles and tendons Pathology of the central nervous system Pathology of the peripheral nervous system Pathology of the integumentary system and the endocrine organs

SYLLABUS

WEEK

Practical topics

Week 1

General practice on all practicals according to the available carcasses.

Description of the pathologic lesions. Introduction and general pathology 1. (histopathology, HP)

Week 2

General practice on all practicals according to the available carcasses.

Description of the pathologic lesions. Introduction and general pathology 2. (histopathology, HP)

Week 3

General practice on all practicals according to the available carcasses.

Description of the pathologic lesions. Inflammations, tumors 1. (HP)

Week 4

General practice on all practicals according to the available carcasses.

Description of the pathologic lesions. Inflammations, tumors 2. (HP)

Week 5

General practice on all practicals according to the available carcasses.

Description of the pathologic lesions. Tumors 1. (HP)

Week 6

General practice on all practicals according to the available carcasses.

Description of the pathologic lesions. Tumors 2. (HP)

Week 7

General practice on all practicals according to the available carcasses.

Description of the pathologic lesions. Lung, kidney 1. (HP)

Week 8

General practice on all practicals according to the available carcasses.

Description of the pathologic lesions. Lung, kidney 2. (HP)

Week 9

General practice on all practicals according to the available carcasses.

Description of the pathologic lesions. Liver, intestines, brain 1. (HP)

Week 10

General practice on all practicals according to the available carcasses.

Description of the pathologic lesions. Liver, intestines, brain 2. (HP)

Week 11

General practice on all practicals according to the available carcasses.

Description of the pathologic lesions. Consultation 1. (HP)

Week 12

General practice on all practicals according to the available carcasses.

Description of the pathologic lesions. Consultation 2. (HP)

Week 13

General practice on all practicals according to the available carcasses.

Description of the pathologic lesions. Practical exam 1.

Week 14

General practice on all practicals according to the available carcasses.

Description of the pathologic lesions. Practical exam 2.

Recommended literature Lecture notes, Ferenc Vetési-Mihály Dobos-Kovács: Colour Atlas of Veterinary Pathology I., Jubb, Kennedy and Palmer’s: Pathology of Domestic Animals Volumes 1-3 (optional)

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SURGERY 3 8th Semester Course description Course

Surgery 3

Department

Department and Clinic of Surgery and Ophthalmology

Language

English

Nature

Mandatory

Year/semester

4th year, spring-term

Credits (ECTS)

6

Lectures (hour/semester)

45

Plenary lectures (hour/semester) Practicals (hour/semester)

45

Responsible teacher

Tibor Németh DVM, Phd, Dipl. ECVS, Professor

Teacher(s)

Tibor Németh DVM, Phd, Dipl. ECVS, Professor, Gábor Bodó DVM, DSc, Dipl. ECVS, Professor, Péter Molnár DVM, research fellow, Dorottya Zólyomi DVM, research fellow, Tamás Ipolyi DVM, senior clinician, Csilla Simon DVM, clinician, Panna Győri DVM, Clinician, Zita Makra DVM, PhD, senior lecturer, Simon Izing DVM, senior clinician, Péter Tóth DVM, PhD, senior lecturer, Pál Tuska DVM, research fellow, Emese Bódai DVM, clinician

Prerequisites

Learning outcome (include skills and competencies, if any) Surgical operative skills on cadavers (laparotomy, gastrotomy, enterotomy, resection/anastomosis, cystotomy, urethrostomy), equine lameness diagnostics, equine basic operative skills (incision and suturing, castration), horse shoing.

Outcome assessment Written Final Examination (MCQ)

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Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Surgery of the stomach II. Surgery of the small intestine. Surgery of the anorectum

Week 2

Surgery of the liver and the spleen. Small animal urogenital surgery I. Surgery of the kidney

Week 3

Small animal urogenital surgery II. Surgery of the ureter and the urinary bladder.

Surgery of the urethra

Week 4

Small animal urogenital surgery III. Surgery of the prostate gland. Cryptorchidism.

Castration. Surgical aspects of the acute abdomen in small animals

Week 5

Lameness examination in small animals I. (diseases of the forelimb)

Week 6

Lameness examination in small animals II. (diseases of the hindlimb) Principles of bone and joint surgery I. (conservative treatment)

Week 7

Principles of bone and joint surgery II. (operative treatment)

Week 8

Fundamentals of small animal neurosurgery

Week 9

Surgery of the urogenital system in horses

Week 10

Evaluation of the lame horse

Week 11

Septic joint in horses, case discussions

Week 12

Principles of fracture repair in horses

Week 13

Aseptic joint diesases (OA, OCD) in horses

Week 14

Diseases of the hoof. Tendon and tendon sheath disorders

WEEK

Practical topics

Week 1

Coeliotomy; Lameness diagnostics I. Conformational abnormalities, palpational findings.

Week 2

Lameness diagnostics I. Conformational abnormalities, palpational findings; Coeliotomy

Week 3

Surgery of the Gastrointestinal Tract; Lameness diagnostics II. Examination of the lame horse in motion, provocation tests

Week 4

Lameness diagnostics II. Examination of the lame horse in motion, provocation tests; Surgery of the Gastrointestinal Tract

Week 5

Surgery of the Urogenital Tract; Lameness diagnostics III. Diagnostic analgesia

Week 6

Lameness diagnostics III. Diagnostic analgesia; Surgery of the Urogenital Tract

Week 7

Practical of surgical diagnostics and therapy I.; Suturing techniques in horses

Week 8

Suturing techniques in horses; Practical of surgical diagnostics and therapy I.

Week 9

Practical of surgical diagnostics and therapy II.; Castration of horses under general anesthesia

Week 10

Castration of horses under general anesthesia; Practical of surgical diagnostics and therapy II.

Week 11

Practical of surgical diagnostics and therapy III.; Horse shoeing practice with farrier expert

Week 12

Horse shoeing practice with farrier expert; Practical of surgical diagnostics and therapy III.

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UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

Recommended literature Auer, J. A. Stick J: Equine surgery. 4th edition, Elsevier, Philadelphia, 2012.

Brinker, N. O. - Piermattei, D. L. - Flo, G. L.: Handbook of small animal orthopaedics and fracture treatment. 4th edition, Elsevier Saunders, 2006 Butler, J. A. ( et. al.) : Clinical radiology of the horse. 2nd edition, Blackwell Science, 2000 Donald, E. Thrall: Textbook of Veterinary Diagnostic Radiology. 6th edition, Elsevier, 2012 Hall, L.W. - Clarke, K. N.: Veterinary anaesthesiology. 9th edition, Wiley and Blackwell, 2008 McIlwraith, C. W. – Robertson J.T.: McIlwraith and Turner’s Equine surgery: advance techniques.

Wiley and Blackwell, 1998 Muir W . W. Hubbel, J. A. E. : Handbook of Veterinary Anesthesia. 5th edition, Elsevier Mosby, 2013 Permattei, D. L.: An atlas of surgical approaches the bones and joints of the dog and cat. Elsevier, 2013 Robinson, N. E.: Currrent therapy in equine medicine 7th edition. Philadelphia, Saunders 2015 Ross.M., Dyson, S.: Diagnosis and Management of Lameness in the horse. 2nd Ed. 2010.

Adam’s and Stashak’s Lameness in Horses. 6th edition, Wiley and Blackwell, 2011 Stashak, T. S.: Equine wound management. 2nd edition, Wiley and Blackwell, 2011.

Tobias KM – Johnston SA: Veterinary Surgery: Small Animal, Elsevier, 2012 Traub-Dargats, J. L - Brown, C. M.: Equine endoscopy. 2nd revised edition, Elsevier 1996

Note(s) Attendance of lectures and practical trainings is compulsory. The exam questions are based on topics of lectures and practical trainings. The attendance of lectures is checked 3 times a semester, the appearance of students at practical trainings is checked at every occasion. The prerequisite of obtaining the approval signature of the semester is the attendance of all practical trainings and at least 1 verified lecture-appearance per semester! Absence of lecture or practical training is regarded as verified in case of illness certified by physician or in case of official faculty programme (e.g. clinical shift). White coat is necessary for practical trainings.

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9TH SEMESTER

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UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

ANIMAL HYGIENE AND HERD HEALTH 2 9th Semester Course description Course

Animal hygiene and herd health 2

Department

Department of Animal Hygiene, Herd Health and Mobile Clinic

Language

English

Nature

Mandatory

Year/semester

5th year, winter-term

Credits (ECTS)

4

Lectures (hour/semester)

45

Plenary lectures (hour/semester) Practicals (hour/semester)

0*

Responsible teacher

Dr. habil. László Könyves, PhD, assoc. professor

Teacher(s)

Prof. Dr. Endre Brydl CSc, Dr. Viktor Jurkovich PhD, Dr. Péter Kovács DVM, Dr. László Könyves PhD, Dr. János Lehoczky DVM, Dr. László Kovács DVM, Péter Hejel, Dr. Csaba Pribenszky PhD, Dr. Eszter Losonczi PhD

Prerequisites

Learning outcome (include skills and competencies, if any) Animal Hygiene is the branch of the veterinary science, which relying on knowledge of physiological and ethological demands of animals, describes the preconditions of health preservation and investigates the pathophysiological changes brought about by adverse environmental effects in order to gain information on the aetiology and pathomechanism of multifactorial diseases. On this basis, animal hygiene systematise the preventive veterinary measures with special reference to their economic consequences. Animal hygiene deals primarily with herds and health protection of the herds, therefore the subject is more or less equivalent to the subject „herd health “” taught in number of the veterinary colleges of the western hemisphere.

Animal hygiene is an interdisciplinary science that lay bridge over animal husbandry and veterinary medicine. Its curriculum involves the management and nutrition technologies of farm animals. The discipline also describes the multilateral effects of housing and nutrition on the health, on the inherited behavioural characteristics of farm and companion animals, on economy of their production and on the rural environment. Based on these knowledge vet¬erinary undergraduates will be trained to become able for critical analysis of housing systems and nutritional regimes, for understanding the aetiology of management related diseases prevailing at herd level, for the application of methods of herd health management in order to prevent and control of multi¬factorial diseases of high economic consequences.

Beyond teaching theoretical and practical knowledge of the discipline we endeavour to implement three goals. First of all we try to form an approach by which the veterinary practitioner becomes able to analyse the production decline, abnormal behaviour and animal diseases in their complex interactions with the environment. We also intend to prepare our undergraduates for the analysis of the economic consequences of their preventive and curative meas¬ures. And last but not least in harmony with other disciplines we regard important to teach our students to esteem and acknowledge the work of experts of other branch of agricultural science.

Theoretical and practical knowledge of animal hygiene is based on animal physiology, husbandry, nutrition, microbiology and immunology. At the same time it contributes to the better understanding of epizootology, state veterinary medicine and food inspection.

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Outcome assessment The course concludes with an oral examination at the end of the 9th semester. Students should answer 2 questions. (See Exam topics at the section “Exam information”.) The first is from basic animal hygiene, the second one relates to herd-health programmes or animal hygienic aspects of keeping food producing animals. Please observe: if the question somehow might be related to your studies in “Applied ethology” the examiner has the right to scrutinise your knowledge in that field of science as well. Putting questions concerning the farm visit is also at the discretion of the examiner.

The exam is scored on a 1 to 5 scale for each question. If the student fails to give adequate answer to either of the two questions the result is failure irrespective to the quality of the response to the other question. In any other case the final score of the exam is the (approximate) arithmetic average of the two scores.

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

1. Mastitis as herd disease (importance, definitions, types) Diagnostical tools and treatment.

2. Factors affecting the development of mastitis. Mastitis pathogen microorganisms.

3. Control of mastitis pathogens in a dairy herd. Hygienic milk sampling methods.

Evaluation ofmicrobiological and antibiogram results.

Week 2

4. Structure and characteristics of the dairy cattle sector, major national and international trends. The main elements of a herd-health based production orientation program in dairy farms. Structure of dairy management. Strategy of the herd-health based production orientation program: draft (protocol).

5. Hygiene of dairy farms. Housing technologies (tie-stall and free-stall housing).

The effect of housing factors on the performance and health of dairy cattle herds.

Examples of novel options, methods, and tools for herd-health monitoring and management work.

6. Computerized herd-management systems, tools for risk assessment and analysis, Herd- diagnostic tools and methods in practice.

Week 3

7. Herd-health management of the metabolic disorders of dairy cows I. Disorders of energy- and acid-base metabolism. Risk factors, prevalence and prevention 8. Herd-health management of the metabolic disorders of dairy cows II. Disorders of protein-, mineral- and vitamin metabolisms. Risk factors, prevalence and prevention 9. Metabolic profile tests (relevance, execution and and the possibility of their use in the veterinary herd-health practice). Relevant metabolic parameters of dairy cows, and interpretation of the normal or pathological range of their values.

Week 4

10. Monitoring of reproductive performance of dairy herds. Reproduction management of dairy cattle. Risk factors affecting reproduction. Management tools and activities for improvement of fertility.

11. Animal hygienic aspects of beef production. Important breeds. General aspects of management. Forms of fattening. Main management related (multifactorial) diseases in beef herds. Risk factors and preventive measures.

12. Monitoring of reproductive performance of beef herds. Reproduction management of beef cattle. Health management of mating bulls

Week 5

13. Animal hygienic and herd health aspects of raising calves. Influental factors on calves’ health and performance. Importance and control of colostrum supply.

Housing technologies and nutrition management of calves.

14. Management related, bacteriological, viral and parasitological diseases of calves.

Methods of control.

15. Animal hygieneic aspects of goat production. General aspects of management.

Important breeds. Keeping technologies. Herd health and reproduction management of dairy goats.

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UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

120

WEEK

Lecture topics

Week 6

16. Animal hygienic aspects of sheep production. Production branches. Breeding management. Management of the pregnant ewes.

17. Management of the broiler lamb production. (Housing and climatic requirements.

Management related, bacteriological, viral and parasitological diseases of broiler lambs. Methods of control.)

18. Practical auditing of welfare in livestock production (primary producers, transport, slaughter)

Week 7

19. Importance of the poultry production. Integrations. Farm technology systems. The role and importance of the hatchery. The installation and rearing of day-old chicks.

20. Specific and non-specific protection against poultry diseases and their animal hygiene aspects (Vaccination program: organization, implementation and control, Farm biosecurity, service period, monitoring program, laboratory samplings) 21. Husbandry and hygiene of Layer flocks (breeeders and egg producers) (Housing technology, Feeding, Farm management, The environmental protection and animal welfare in the layer farm.

Week 8

22. Diseases of the bovine digit. Functional hoof trimming.

23. Monitoring and preventive measures of hoof disorders.

24. Herd health management of table rabbit production. (Breeds. Breeding management. Housing.) Management and nutrition related multifactorial diseases of rabbit and itsâ&#x20AC;&#x2122; prevention.

Week 9

25. Quality characteristics of table eggs. Health protection of layer flocks: bacterial and viral diseases and their control, Field vaccination program. Management related diseases.

26. Husbandry and hygiene of Broiler flocks: housing technology, feeding, stable and environment 27. How to control the homogeneity of production. Health protection of broiler flocks: infectious and non-infectious diseases and their control, field vaccination program.

Week 10

28. Husbandry and hygiene of Turkey flocks: Production goals, Breeds, housing technologies, Breeding management, how to raise turkey chicks: brooding, rearing, fattening.

29. Health protection of turkey flocks: Diseases caused by bacterial, viral and parasitic diseases and their control, Management related diseases, Vaccination and vitamin program, Diseasesâ&#x20AC;&#x2122; prevention, Laboratory monitoring 30. Husbandry and hygiene of Duck flocks: Production goals, Breeds, housing technologies, Rearing, Feeding, The technology of roast duck production; meat, liver, feather and egg production ability of duck.

Week 11

31. Health protection of Duck flocks: Infectious diseases: bacteria, viruses, parasites, fungies and their control; Non-infectious diseases: metabolic diseases, uricosis, feather pecking, mycotoxicoses, botulism, hatching weakness.

32. Husbandry and hygiene of Goose flocks: Breeds and hybrids, breeding technologies, Technology of goose production: meat, liver and feather production.

33. Health protection of goose flocks: Infectious diseases: bacteria, viruses, parasites and their control; Non-infectious diseases: hatching weakness. Factors endangering goose health and food safety and their troubleshooting.

Week 12

34. Management and organisation of the pig production (breeds, pure breeding, hybridisation programmes, breeding pyramid, breeding organisations) 35. Management and housing technologies in the pig production (mono-, bi- and three-phase housing systems, flowchart of operation, farrowing systems, housing of weaned pigs, fattening systems, housing of the sow) 36. Herd health management of reproduction of the sow (monitoring of the reproductive performance, environmental factors affecting litter size, and the number of non-productive days)

SYLLABUS

WEEK

Lecture topics

Week 13

37. The periparturient disease complex of the sow, leg disorders and culling strategies 38. Herd health management from farrowing till weaning (pre-weaning mortality â&#x20AC;&#x201C; risk factors, postparturient losses, prevention) 39. Herd health programme from weaning till the end of the post-weaning period (factors affecting weight gain after weaning, bacterial and viral diseases around weaning, prevention of peri-weaning enteral diseases)

Week 14

40. Herd health management of the fattening pig. Postweaning Multisystemic Wasting Syndrome. Management practices to reduce expensive feed wastage.

41. Herd health control of the Porcine Respiratory Disease Complex (basic principles, diagnosis at herd level, control measures).

42. Production oriented, planned veterinary programmes for the swine industry (advances in health control, components of the planned animal health and production program, check lists). Pathomorphological data collection in slaughterhouse, analysis and reporting.

Recommended literature BRAND A. - NORDUIZEN J.P.T.M. â&#x20AC;&#x201C; SCHUKKEN Y.H.: Herd Health and Production Management in Dairy Practice. Wageningen: Wageningen Pers, 1996.

RADOSTITS O.M.: Herd Health Food Animal Production Medicine. W.B. Saunders Company, 2001.

EKESBO, I. 2011. Farm animal behaviour, CABI, Wallingford, UK, ISBN: 9781845937706Jensen, P. 2009. The ethology of domestic animals, CABI, Wallingford, UK, ISBN: 9781845935368 ALAND, A. - BANHAZI, T. (ed.) Livestock housing. Modern management to ensure optimal health and welfare of farm animals ISBN: 978-90-8686-217-7

Note(s) Attendance of the theoretical lectures is suggested because the curriculum is subjected to continuous up-dating. The attendance of the farmvisit is compulsory according to the official schedule.

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UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

EPIDEMIOLOGY AND INFECTIOUS DISEASES 1 9th Semester Course description Course

Epidemiology and infectious diseases 1

Department

Department of Microbiology and Infectious Diseases

Language

English

Nature

Mandatory

Year/semester

5th year, winter-term

Credits (ECTS)

3

Lectures (hour/semester)

75

Plenary lectures (hour/semester) 15 Practicals (hour/semester)

15

Responsible teacher

Fodor, Lรกszlรณ

Teacher(s)

Fodor, Lรกszlรณ Professor; Forgรกch, Petra Senior assistant; Hornyรกk, ร kos Head of laboratory; Lล rincz, Mรกrta Senior assistant; Makrai, Lรกszlรณ Associate professor; Rusvai, Miklรณs Professor; Varga, Jรกnos Professor emeritus

Prerequisites

Learning outcome (include skills and competencies, if any) After absolving the subject the students will be able to recognise the clinical signs and post mortem lesions of the infectious diseases of animals, promote diagnosis of infectious diseases of animals by appropriate sampling, diagnose infectious diseases of animals by using laboratory methods, evaluate the diagnostic results of infectious diseases of animals, treat and prevent infectious diseases, introduce and implement preventive measures, apply veterinary and public health measures.

Outcome assessment There are two midterms during the semester and their result is the basis of the parctical note.

122

SYLLABUS

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

General epidemiology

Week 2

Diseases caused by circoviruses, parvoviruses, papilloma viruses and polyoma viruses.

Week 3

Diseases caused by adenoviruses and herpesviruses.

Week 4

Diseases caused by herpesviruses and poxviruses.

Week 5

Diseases caused by poxviruses, Africal swine fever, foot and mouth disease

Week 6

Diseases caused by picornaviruses, astroviruses, caliciviruses, hepatitis E, infectious bursal disease

Week 7

Diseases caused by reoviruses and flaviviruses.

Week 8

Classical swine fever, diseases caused by bunyaviruses.

Week 9

Diseases caused by orthomyxoviruses and paramyxoviruses.

Week 10

Diseases caused by paramyxoviruses, arteviruses and coronaviruses.

Week 11

Diseases caused by coronaviruses and rhabdoviruses.

Week 12

Diseases caused by retroviruses and bornaviruses.

Week 13

Transmissible encephalopathies, anthrax, diseases caused by clostridia.

Week 14

Diseases caused by clostridia, staphylococcoses and streptococcoses.

WEEK

Practical topics

Week 5

General aspects of diagnosis of infectious diseases, sampling to laboratory examinations, transportation of the samples.

Week 6

Differential diagnosis of infectious diseases of cattle caused by viruses.

Week 7

Differential diagnosis of infectious diseases of dogs and cats caused by viruses.

Week 8

Differential diagnosis of infectious diseases of swine caused by viruses.

Week 9

Differential diagnosis of infectious diseases of poultry caused by viruses.

Week 10

Differential diagnosis of infectious diseases of horses caused by viruses.

123

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

FOOD HYGIENE 1 9th Semester Course description Course

Food hygiene 1

Department

Department of Food Hygiene

Language

English

Nature

Mandatory

Year/semester

5th year, winter-term

Credits (ECTS)

4

Lectures (hour/semester)

60

Plenary lectures (hour/semester) 0 Practicals (hour/semester)

30

Responsible teacher

Dr. Péter Laczay

Teacher(s)

Dr. József Lehel, Dr. Katalin Lányi, Dr. Dániel Pleva, Dr. Katalin Szakmár, Dr. Dóra Tőzsér, Dr. Lívia Darnay

Prerequisites

Learning outcome (include skills and competencies, if any) Essential theoretical knowledge and hands-on experience in general food hygiene ant the hygiene of milk and milk products

Outcome assessment Practical mark Weekly schedule of lectures and practicals

124

WEEK

Lecture topics

Week 1

Introduction, basic terms, historical aspects. Foodborne hazards, adverse health effects.

Week 2

Food microbiology: growth and death of microorganisms 1.

Food microbiology: growth and death of microorganisms 2.

Week 3

Pathogen microorganisms in foodstuffs 1: Salmonella, Campylobacter, E. coli, Yersinia enterocolitica. Pathogen microorganisms in foodstuffs 2: Listeria monocytogenes, Shigella, Enterobacter, Vibrio spp., Staphylococcus aureus.

Week 4

Pathogen microorganisms in foodstuffs 3: Clostridium botulinum, Clostridium perfringens, Bacillus cereus, viruses, parasites, prions.

Pathogen microorganisms in foodstuffs 4: regulation of microbiological food safety, controlling Salmonella, microbiological monitoring.

Week 5

Chemical-toxicological food safety 1: fundamentals of regulation, veterinary medicinal products, not allowed (banned) active substances. Chemical-toxicological food safety 2: contaminants of biological origin, contaminants of technological origin.

Week 6

Chemical-toxicological food safety 3: pesticide residues, contaminants of environmental origin. Spoilage, preservation and other treatment of foodstuffs. Spoilage of microbiological, chemical and biochemical origin.

Week 7

Physical, chemical, biological and combined preservative procedures.

Week 8

Fundamentals of food-hygiene legal regulation.

SYLLABUS

WEEK

Lecture topics

Week 9

General hygiene rules, food safety assurance systems (HACCP).

Week 10

Hygiene of milk production: composition and properties of milk.

Hygiene of milking and handling of raw milk at the farm.

Week 11

Milk hygiene aspects of mastitis. Microbiology of raw milk, milk hygiene aspects of zoonoses.

Week 12

Milk hygiene aspects of zoonoses and other (pathogen) causatives mediated by milk.

Chemical contamination of milk.

Week 13

Hygiene of milk processing: general operations. Technological hygiene of milk products’ manufacture: heat treated milk, acidic milk products.

Week 14

Technological hygiene of further milk products’ manufacture: butter and cream products, cheese and cheese products, condensed and powdered milk products.

Technological hygiene of further milk products’ manufacture: butter and cream products, cheese and cheese products, condensed and powdered milk products.

WEEK

Practical topics

Week 1

Aims and requirements of practicals, occupational health rules.

Week 2

Microbiological examination methods, determination of viable cell count: plate pouring method, spreading method, the end point dilution, membrane filtration, MPN (most probable number) method.

Week 3

Evaluation of the results of microbiological examination. Rapid microbiological methods: direct cell enumeration, examination of metabolites, instrumental culturing methods.

Week 4

Practical aspects of food safety criteria: Listeria monocytogenes, Salmonella spp.

Week 5

Practical aspects of process hygiene criteria: aerob colony count,Enterobacteriaceae, E. coli, other microbes

Week 6

Practical aspects of spoilage, preservation: heat treatment, preservatives, water removal

Week 7

Official sampling

Week 8

Chemical-toxicological food safety: official monitoring systems

Week 9

Chemical-toxicological food safety: screening investigations, confirmatory, large instrument analysis

Week 10

Physical, chemical properties of milk, practical aspects of different heat treatment methods

Week 11

Technological hygiene of sour milk and cream processing

Week 12

Technological hygiene of butter and sweet cream production

Week 13

Technological hygiene of cheese making

Week 14

Supplementary practicals

Recommended literature Textbook: P. Laczay: Food hygiene, food chain safety. Textbook, Budapest, 2015.

Erdősi, O.-Lányi, K.-Lehel, J.-Szili, Zs.: Food hygiene praticals I. A/3 Nyomdaipari és Kiadói Szolgáltató Kft., Budapest, 2016.

Materials of lectures and practicals.

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UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

INTERNAL MEDICINE 3 9th Semester Course description Course

Internal medicine 3

Department

Department and Clinic of Internal Medicine

Language

English

Nature

Mandatory

Year/semester

5th year, winter-term

Credits (ECTS)

6

Lectures (hour/semester)

36

Plenary lectures (hour/semester) Practicals (hour/semester) Responsible teacher

dr. Ferenc Manczur

Teacher(s)

dr. Ágnes Sterczer, dr. Ákos Máthé, dr. Ákos Pákozdy, dr. Éva Balogh, dr. Ferenc Manczur, dr. Fruzsina Falus, dr. Krisztina Kungl, dr. Márton Balogh, dr. Noémi Tarpataki, dr. Péter Vajdovich, dr. Roland Psáder, dr. Zsuzsanna Vizi

Prerequisites

Learning outcome (include skills and competencies, if any) The goal of the subject is teaching of non-infectious diseases of the various organs and organ systems of dogs and cats. Etiology and pathogenesis of these diseases are discussed in details as well as diagnosis, and prevention.

Outcome assessment Complex final exam

126

SYLLABUS

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Endocrine diseases of dogs and cats.

Week 2

Endocrine diseases of dogs and cats.

Metabolic diseases of dogs and cats, obesitas, hypo-, and hypervitaminosis.

Week 3

Liver diseases of dogs and cats.

Week 4

Liver diseases of dogs and cats.

Hemopoietic diseases.

Week 5

Hemopoietic diseases.

Week 6

Neoplastic diseases.

Week 7

Respiratory and gastrointestinal endoscopy.

Week 8

Diseases of the canine and feline nervous system.

Week 9

Diseases of the canine and feline nervous system.

Seizures of extracerebral origin and epilepsy.

Week 10

Diseases of the canine and feline nervous system.

Urinary diseases of dogs and cats

Week 11

Urinary diseases of dogs and cats

Week 12

Urinary diseases of dogs and cats.

Diseases of the skin of dogs and cats.

Week 13

Diseases of the skin of dogs and cats.

Week 14

Diseases of the skin of dogs and cats.

Diseases of the external ear.

Recommended literature Obligatory book: Nelson, C.R., Couto, G.: Small Animal Internal Medicine. 5th ed. Mosby; St. Luis. 2014.

Suggested books: Feldman, S.R. et al.: Skin diseases of the dog and cat (2nd ed.) Blackwell Publishing, Iowa, 2005.

Yin, S.: The Small Animal Veterinary Nerdbook. 3.ed., Cattledog Publishing, Davis, 2010.

Plunkett, S.J.: Emergency Procedures for the Small Animal Veterinarian-, 3rd ed. Saunders, Elsevier, Edinburgh. Paperback â&#x20AC;&#x201C;2013.

Lorenz, M.D. et al.: Small animal medical diagnosis. 3rd ed. Wiley-Blackwell, Ames. 2009.

Tilley, L.P.; Burtnick, N.: ECG for the small animal practitioner. Published by Teton New Media.

Teton NewMedia, Jackson, 2009.

Nyland, T. G.-Mattoon, J. S. Small animal diagnostic ultrasound. 3rd ed. W. B. Saunders, Philadelphia, 2015.

Penninck, D., dâ&#x20AC;&#x2122;Anjou, M-A.: Atlas of small animal ultrasonography, 2nd ed. Blackwell Publishing, Ames, 2015.

Ware, W. A.: Cardiovascular disease in small animal medicine. Manson Publishing Ltd. , London, 2007.

Ware, W. A.: Small animal cardiopulmonary medicine. Manson Publishing, London, 2011.

Ettinger, S.J.-Feldman E.C.-Cote, E. (eds.): Textbook of veterinary internal medicine. Diseases of the dog and cat. Expert consult, 8th ed., Saunders, St. Luis, 2017.

Greene, C.E.: Infectious diseases of the dog and cat. 4th ed. Elsevier, St. Luis, 2011.

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UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

OBSTETRICS AND REPRODUCTION 3 9th Semester Course description Course

Obstetrics and reproduction 3

Department Language

English

Nature

Mandatory

Year/semester

5th year, winter-term

Credits (ECTS)

6

Lectures (hour/semester)

30

Plenary lectures (hour/semester) Practicals (hour/semester)

30

Responsible teacher

Sándor CSEH, DVM, Ph.D., D.Sc., Professor

Teacher(s)

Laszlo SOLTI, DVM, Ph.D., D.Sc., member of the Hun. Academy of Science, Professor József RÁTKY, DVM, Ph.D., D.Sc., Professor Ottó SZENCI, DVM, Ph.D., D.Sc., Professor Emeritus András HORVÁTH, DVM, Ph.D. Zoltán SZELÉNYI, DVM, Ph.D. Lea LÉNÁRT, DVM, Ph.D.-student Anna CSEPREGHY, DVM, clinician Linda MÜLLER, DVM, Ph.D.-student, clinician Dóra KISPÁL, DVM, clinician Szilvia FARKAS, DVM, Ph.D., clinician Eszter SZILÁGYI, DVM, clinician Bence SOMOSKŐI, MSc., Ph.D., Research fellow

Prerequisites

Outcome assessment 9th semester: final exam (preconditions to take the exam: valid, accepted three semesters, completed obligatory participation in specified diagnostic and therapeutic activities with written documentation (“Clinical card”)

128

SYLLABUS

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Embryo transfer I. History and practical application of biotechnology in animal reproduction. (Importance,principles. Multiple ovulation) (Solti, L.)

Week 2

Basic principles of embryo freezing. Embryo freezing techniques. (Solti, L.)

Week 3

Embryo transfer II. (Embryo recovery in different species. The morphological evaluation of recovered embryo) (Solti, L.)

Week 4

Embryo transfer III.(Surgical and non-surgical methods for transfer of embryos in cattle and other species). (Solti, L.)

Week 5

Embryo transfer IV. (micromanipulation of embryos) (Solti L.)

Week 6

Principles of further advanced techniques in reproductive biotechnology.

(Sexdetermination; production of sex-sorted semen; cloning; gene manipulation techniques; production of transgenic animals) (Solti L.)

Week 7

Structure of the male reproductive organs. Neuroendocrine regulation of the male reproduction. Endocrine and exocrine function of the testicles. Thermoregulation of the testis. (Cseh S.)

Week 8

Physiology and pathology of epididymis and accessory sexual glands. The contagious epidymiditis and orchitis of rams. (Cseh, S.)

Week 9

Artificial insemination. I. Semen collection, evaluation, dilution, and cryopreservation. (Cseh S.)

Week 10

Artificial inseminationII. (cattle, pig, small ruminants) (Cseh, S.)

Week 11

Artificial inseminationIII. (rabbit, horse) (Cseh, S.)

Week 12

Artificial inseminationIV. (dog and cat) (Cseh, S.)

Week 13

Infertility in males. The contagious epididymiditis and orchitis of rams.(Cseh, S.)

Week 14

Guest lecturer â&#x20AC;&#x201C; to be determined later Guided by S. Cseh

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130

WEEK

Practical topics

Week 1

Participants:Group 5-8.

8.15-10.30: Group A: Ophtalmology, Group B: Andrology: Collection of semen. Semen quality in stallions. Technical presentation of AI inthe mare (A. Horváth) 11.00-13.15: Group B: Ophtalmology, Group A: Andrology: Collection of semen. semen quality in stallions. Technical presentation of AI inthe mare (A. Horváth) Participants:Group 1-4.

Obst. practical hall (building L, first floor) 8.00–10.15: Group 3-4.

10.15–12.30: Group 1-2.

Subjects: Reproductive examination of the female dog, Methods for estrus stage determination in bitch (Sz. Farkas)

Week 2

Participants: Group 1-4.

Subject: Identical (A. Horváth) Participants: Group 5-8.

8.15-10.30: Group A: Ophtalmology, Group B: Andrology: Collection of semen. Semen quality in stallions. Technical presentation of AI inthe mare (A. Horváth) 11.00-13.15: Group B: Ophtalmology, Group A: Andrology: Collection of semen. semen quality in stallions. Technical presentation of AI inthe mare (A. Horváth) Participants:Group 1-4.

Obst. practical hall (building L, first floor) 8.00–10.15: Group 3-4.

10.15–12.30: Group 1-2.

Subjects: Reproductive examination of the female dog, Methods for estrus stage determination in bitch (Sz. Farkas)”

Week 3

Participants: Group 5-8.

8.15-11.15: Group A: Andrology: Reproductive examination of stallion, bull, boar, ram and buck: Evaluation of potential breeding soundness (O. Szenci), Group B: Andrology: Collection of semen in the boar. Technical presentation of AI in ruminants, sow and rabbit (A. Horváth) 11.30-14.30: Group B: Andrology: Reproductive examination of stallion, bull, boar, ram and buck: Evaluation of potential breeding soundness (O. Szenci), Group A: Collection of semen in the boar. Technical presentation of AI in ruminants, sow and rabbit (A. Horváth) Participants: Group 1-4.

Subject: Identical (A. Horváth) Participants: Group 5-8.

8.15-10.30: Group A: Ophtalmology, Group B: Andrology: Collection of semen. Semen quality in stallions. Technical presentation of AI inthe mare (A. Horváth) 11.00-13.15: Group B: Ophtalmology, Group A: Andrology: Collection of semen. semen quality in stallions. Technical presentation of AI inthe mare (A. Horváth) Participants: Group 1-4.

Obst. practical hall (building L, first floor) 8.00–10.15: Group 3-4.

10.15–12.30: Group 1-2.

Subjects: Reproductive examination of the female dog, Methods for estrus stage determination in bitch (Sz. Farkas)

Week 4

Participants: Group 1-4.

Subject: Identical (O. Szenci and A. Horváth)

SYLLABUS

Week 5

Participants: Group 5-8.

Subject: Visit to Bos-Genetic (AI Center – Martonvásár) Organizer: S. Cseh Supervisor: B. Somoskői Participants: Group 1-4.

Obst. practical hall (building L, first floor) 8.00–10.15: Group 3-4.

10.15–12.30: Group 1-2.

Subjects: Clinical aspects of male reproductive disorders (L.Müller)

Week 6

Participants: Group 1-4.

Subject: Identical Organizer: S. Cseh Supervisor:B. Somoskői.

Participants: Group 5-8.

Obst. practical hall (building L, first floor) 8.00–10.15: Group 7-8.

10.15–12.30: Group 5-6.

Subjects: Identical (L. Müller)

Week 7

Participants: Group 5-8.

Subject: Visit to the Research Centre for Farm Animal Gene Conservation (in Gödöllő) Organizer: S. Cseh Supervisor: B. Somoskői Participants: Group 1-4.

Obst. practical hall (building L, first floor) 8.00–10.15: Group 3-4.

10.15–12.30: Group 1-2.

Subjects: Clinical signs and treatment of vaginal prolapse and vaginal tumors, Clinical case discussions(L. Müller)

Week 8

Participants: Group 1-4.

Subject: Identical Organizer: S. Cseh Supervisor: B. Somoskői Participants: Group 5-8.

Obst. practical hall (building L, first floor) 8.00–10.15: Group 7-8 10.15–12.30: Group 5-6.

Subjects: Identical (L. Müller)

Recommended literature D.E. Noakes, Timothy J. Parkinson and Gary C.W. England (eds):Veterinary Reproductionand Obstetrics. 9th edition, Saunders Elsevier, London, 2009 M.H. Pineda and Michael P. Dooly (eds): McDonald’s Veterinary Endocrinology and Reproduction. 5th edition, Iowa State Press A Blackwell Publishing Company, 2003.

R.S. Youngquist and Walter R.Threlfall (eds): Current Therapy in Large Animal Theriogenology.

2nd edition, Sounders Elsevier, St. Louis, Missouri, 2007.

E.C.Feldman, R.W. Nelson: Canine and feline Endocrinology andreproduction. 3rd edition, Saunders 2004.

P.L. Senger: Pathways to pregnancy and parturition 2nd edition, Pullman: Current Conceptions Inc. 2003. (3rd edition, 2011.)

M. Sandholm, T. Honkanen-Buzalski, L. Kaartinen, S. Pyörala: The bovine udder and mastitis. 1st edition, University of Helsinki, faculty of Veterinary Medicine, Helsinki, 1995.

Gary England, Angelika von Heimendahl: BSAVA Manual of Canine and Feline Reproduction and Neonatology. 2nd edition, British Small Animal Vererinary Association, Gloucester, 2010.

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UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

OPHTHALMOLOGY 9th Semester Course description Course

Ophthalmology

Department

Department and Clinic of Surgery and Ophthalmology

Language

English

Nature

Mandatory

Year/semester

5th year, winter-term

Credits (ECTS)

3

Lectures (hour/semester)

14

Plenary lectures (hour/semester) Practicals (hour/semester)

9

Responsible teacher

Zsolt Szentgรกli, DVM, honorary associate professor

Teacher(s)

Zsolt Szentgรกli DVM, honorary associate professor, Zita Makra DVM, PhD, senior lecturer

Prerequisites

Learning outcome (include skills and competencies, if any) basic ophthalmologic diagnostic and threapeutic skills (physical exam, vital staining, ophthalmoscopy, usage of drops and ointments, subconjunctival injection, subpalpebral drainage, lacrimal duct lavage)

Outcome assessment Written Semi-final examination (MCQ)

132

SYLLABUS

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Ocular pharmacology

Week 2

Basic diagnostic procedures

Week 3

The eyelids I.

Week 4

The eyelids II.

Week 5

The conjunctiva

Week 6

The third eyelid

Week 7

The cornea I.

Week 8

The cornea II.

Week 9

The cornea III.

Week 10

The lacrymal system

Week 11

The uvea

Week 12

Specific ocular conditions in horses

Week 13

The lens

Week 14

The glaucoma

WEEK

Practical topics

Week 1

Equine ocular examination (diagnostic instruments, examination protocol, supplementary diagnostic procedures on sedated horses); Subconjunctival injection, regional nerve blocks, subpalpebral lavage device, lavage of the nasolacrimal duct on cadaver animals)

Week 2

Equine ocular examination (diagnostic instruments, examination protocol, supplementary diagnostic procedures on sedated horses); Subconjunctival injection, regional nerve blocks, subpalpebral lavage device, lavage of the nasolacrimal duct on cadaver animals)

Week 3

Examination of the eye I.

Week 4

Examination of the eye I.

Week 7

Examination of the eye II.

Week 8

Examination of the eye II.

Recommended literature Barnett, K. C.: Colour atlas of veterinary ophtalmology. London, Wolfe Medical Publ., 1989 Gelatt, K. N et al.: Veterinary ophtalmology. 5th edition, Wiley and Blackwell, 20

Note(s) Attendance of lectures and practical trainings is compulsory. The exam questions are based on topics of lectures and practical trainings. The attendance at practical trainings is checked at every occasion. The prerequisite of obtaining the approval signature of the semester is the attendance of all practical trainings. Absences are regarded as verified in case of illness certified by physician or in case of official faculty programme (e.g. clinical shift). White coat is necessary for practical trainings.

133

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

STATE VETERINARY MEDICINE 1 9th Semester Course description Course

State veterinary medicine 1

Department Language

English

Nature

Mandatory

Year/semester

5th year, winter-term

Credits (ECTS)

1

Lectures (hour/semester)

30

Plenary lectures (hour/semester) Practicals (hour/semester)

0

Responsible teacher Teacher(s) Prerequisites

Learning outcome (include skills and competencies, if any) Presentation of the legislation relating to the veterinary profession, structure and duties of international veterinary organisations, the general preventive measures of notifiable infectious animal diseases

Outcome assessment Signature Weekly schedule of lectures and practicals

134

WEEK

Lecture topics

Week 1

Main aims and objectives of the subject; World Organization for Animal Health (OIE),

Week 2

FAO, WHO, WTO, OECD, Council of Europe

Week 3

European Union (institutions, legislation)

Week 4

Fields of veterinary legislation, Structure and duties of state veterinary services, Veterinary checks and certifications, Veterinary medicinal products

Week 5

Notification of animal diseases, Measures for the control of notifiable animal diseases

Week 6

Veterinary legislation on animal keeping

Week 7

Animal welfare rules of the European Union

Week 8

Veterinary legislation on the transport of animals and animal products, Veterinary legislation on the killing of animals

Week 9

Disposal of carcasses and animal waste, Disinfection

Week 10

Animal fairs, markets and exhibitions, Identification and registration of animals

Week 11

Control strategies against infectious diseases

Week 12

Veterinary laboratories; diagnostic tests

Week 13

Veterinary public health

Week 14

Control of notifiable zoonotic diseases

SYLLABUS

10TH SEMESTER

135

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

ANIMAL HEALTH ECONOMY MANAGEMENT 10th Semester Course description Course Department Language Nature Year/semester Credits (ECTS) Lectures (hour/semester) Plenary lectures (hour/semester) Practicals (hour/semester) Responsible teacher Teacher(s) Prerequisites

Animal health economy management Department of Veterinary Forensics and Economics English Mandatory 5th year, spring-term 2 30 30 0 Dr. László Ózsvári Dr. László Ózsvári, Dr. István Fodor

Learning outcome (include skills and competencies, if any) The students will gain knowledge of the basics of veterinary business management, the legal and economic aspects of small, mixed and large animal vet practices including business planning, investment decisions, pricing strategy, marketing, communication, licensing schemes, ethics, etc., and the basic principles of animal health economics with special regard to the production and economics losses due to the herd health diseases and the financial analyses of the veterinary interventions, measurements (e.g., vaccinations, medications).

Outcome assessment written exam Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1 Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8 Week 9 Week 10 Week 11 Week 12 Week 13 Week 14

General introduction. Economic decision-making in animal health management Production function, costs, cost functions Partial budgeting Cost-benefit analysis Decision analysis Farm budgets for livestock Herd health economics of swine and poultry Herd health economics of cattle Vet practice management Marketing management Financial planning and pricing Practice valuation (buying-selling) Business planning Investment decisions

Recommended literature Dijkhuizen, A. A.: Animal Health Economics. Sydney, 1997., Ózsvári L.: Main characteristics and expectable tendencies of the management, income and number of patients in Hungarian small animal and mixed practices. MBA Thesis. Webster Univ. – Szent István Univ., Budapest, 60. pp.

136

SYLLABUS

EPIDEMIOLOGY AND INFECTIOUS DISEASES 2 10th Semester Course description Course

Epidemiology and infectious diseases 2

Department

Department of Microbiology and Infectious Diseases

Language

English

Nature

Mandatory

Year/semester

5th year, spring-term

Credits (ECTS)

5

Lectures (hour/semester)

60

Plenary lectures (hour/semester) Practicals (hour/semester)

20

Responsible teacher

Fodor, Lรกszlรณ

Teacher(s)

Fodor, L., Makrai., Rusvai, M.

Prerequisites

Learning outcome (include skills and competencies, if any) After absolving the subject the students will be able to recognise the clinical signs and post mortem lesions of the infectious diseases of animals, promote diagnosis of infectious diseases of animals by appropriate sampling, diagnose infectious diseases of animals by using laboratory methods, evaluate the diagnostic results of infectious diseases of animals, treat and prevent infectious diseases, introduce and implement preventive measures, apply veterinary and public health measures.

Outcome assessment Two written tests are organised during the semester, and the final exam consists of a written test and an oral exam.

137

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Streptococcoses, erysipelas, listeriosis, diseases caused by Corynebacteria.

Week 2

Tuberculosis, paratuberculosis.

Week 3

Actinomycosis, nocardiosis, dermatophilosis, diseases caused by R. equi, diseases caused by E. coli

Week 4

Diseases caused by E. coli, necrobacillosis, salmonellosis.

Week 5

Salmonellosis, yersiniosis.

Week 6

Pasteurelloses.

Week 7

Anatifestifer disease, ornithobacteriosis, actinobacillosis, haemophilosis.

Week 8

Brucellosis.

Week 9

Tularaemia, bordetellosis, malleus, melioidosis, diseases caused by Moraxella and Bartonella.

Week 10

Campylobacteriosis, proliferative enteropathies, borreliosis

Week 11

Swine dysentery, rabbit sysphilis, leptospirosis.

Week 12

Mycoplasmosis.

Week 13

Mycoplasmosis, chlamydiosis.

Week 14

Q-fever, diseases caused by Rickettsiae

WEEK

Practical topics

Week 2

Differential diagnosis of diseases of sheep and goats caused by viruses.

Week 3

Differential diagnosis of diseases of cattle caused by bacteria.

Week 4

Differential diagnosis of diseases of swine caused by bacteria.

Week 5

Differential diagnosis of diseases of horses caused by bacteria.

Week 7

Differential diagnosis of diseases of dogs and cats caused by bacteria.

Week 9

Differential diagnosis of diseases of sheep and goats caused by bacteria.

Week 10

Differential diagnosis of diseases of poultry caused by bacteria.

Week 13

Retake

Recommended literature The detailed recommended literature is available on the homepage.

138

SYLLABUS

FOOD HYGIENE 2 10th Semester Course description Course

Food hygiene 2

Department

Department of Food Hygiene

Language

English

Nature

Mandatory

Year/semester

5th year, spring-term

Credits (ECTS)

5

Lectures (hour/semester)

60

Plenary lectures (hour/semester) 0 Practicals (hour/semester)

30

Responsible teacher

Dr. Péter Laczay

Teacher(s)

Dr. József Lehel, Dr. Katalin Lányi, Dr. Dániel Pleva, Dr. Katalin Szakmár, Dr. Dóra Tőzsér, Dr. Lívia Darnay

Prerequisites

Learning outcome (include skills and competencies, if any) Essential theoretical knowledge and hands-on experience in meat hygiene and hygiene of other foods of animal and plant origin, and food hygiene administration

Outcome assessment Final exam (combined written and oral exam) that covers the whole curriculum of the subject, i.e.

Food Hygiene 1 and Food Hygiene 2.

Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Definition, ageing, composition and properties of meat Basic terms of meat inspection.

Ante mortem inspection at the farm and slaughterhouse

Week 2

Post mortem meat inspection, meat inspection diagnosis Decisions concerning meat, animal health marking, specific risk materials, slaughterhouse waste

Week 3

Technological hygiene of slaughter of swine Technological hygiene of slaughter of ruminants

Week 4

Meat inspection of pigs and ruminants Technological hygiene of poultry and lagomorphs slaughter, meat inspection of poultry and rabbit

Week 5

Hygiene of game processing, meat inspection of farmed and hunted wild game Hygiene of egg production and the manufacture of egg-products, inspection of eggs and egg-products

Week 6

Hygiene conditions and official control of the processing of fishery products and the production of live bivalve molluscs Production and processing hygiene of foodstuffs of plant origin 139

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

WEEK

Lecture topics

Week 7

Processing hygiene of meat products Judgement of meat: septicaemic conditions, organoleptic changes

Week 8

Judgement of meat: OIE listed diseases I Judgement of meat: OIE listed diseases II

Week 9

Judgement of meat: animal diseases/infections not included in the OIE list Official food control: legal regulation, organisation, types and tasks

Week 10

Official food control: registration and approval of food business establishments, audit of good hygiene practices and the HACCP system Official control of the distribution of foodstuffs: wholesale and retail establishments

Week 11

Official control of catering services and mass caterers I Official control of catering services and mass caterers II

Week 12

Official food control: basis of the risk-based official controls

Week 13

Official food control: control of the traceability system and the compliance with microbiological criteria, the rules of official sampling Official control of international trade of foods

Week 14

Control of small scale food production /processing/marketing Measures in the event of non-compliance, sanctions

WEEK

Practical topics

Week 1

Food hygiene significance and examination of water

Week 2

Labelling and packaging of food

Week 3

Examination of properties of meat and its organoleptic alterations

Week 4

Significance and utilization of food waste

Week 5

Practical aspects of meat inspectio

Week 6

Inspection of egg and egg-products

Week 7

Meat inspection of fish and other aquatic animals

Week 8

Technological and food hygiene aspects of processing of cured meat products

Week 9

Technological and food hygiene aspects of processing of stuffed meat products 1. (raw-smoked and fermented meat products)

Week 10

Technological and food hygiene aspects of processing of stuffed meat products 2. (cooked, smoked meat products)

Week 11

Technological and food hygiene aspects of production of canned products

Week 12

Inspection of establishment producing food of plant origin

Week 13

Case studies – Actual food hygiene questions

Week 14

Supplementary practical

Recommended literature Textbook: P. Laczay: Food hygiene, food chain safety. Textbook, Budapest, 2015.

Erdősi, O.-Lányi, K.-Lehel, J.-Szili, Zs.: Food hygiene praticals II. A/3 Nyomdaipari és Kiadói Szolgáltató Kft., Budapest, 2017.

Materials of lectures and practicals.

140

SYLLABUS

FORENSIC VETERINARY MEDICINE 10th Semester Course description Course

Forensic veterinary medicine

Department Language

English

Nature

Mandatory

Year/semester

5th year, spring-term

Credits (ECTS)

3

Lectures (hour/semester)

35

Plenary lectures (hour/semester) Practicals (hour/semester)

0

Responsible teacher Teacher(s) Prerequisites

Learning outcome (include skills and competencies, if any) Teaching the ethical, legal and criminal liability of the veternarian, how to prevent and solve legal disputes. Discussing the infectious and non-infectious animal diseases from the point of view of giving veterinray expert opinion

Outcome assessment Written examination focusing on the topics discussed on the lectures. The students present the knowledge on the liability questions and if they can assist the courts as a veterinary expert settling the legal disputes on the field of liability for damages and warranty Weekly schedule of lectures and practicals

WEEK

Lecture topics

Week 1

Introduction, Courts of law, public prosecutors, Law of procedures

Week 2

Law of contracts, Warranty

Week 3

Law of torts

Week 4

Evidences, witness testimony,Veterinary expert opinion

Week 5

Criminal procedure

Week 6

Criminal liability of the veterinarian

Week 7

Forensic aspects of infectious diseases

Week 8

Forensic aspects of small animal diseases, Forensic aspects of ruminant diseases

Week 9

Forensic aspects of equine diseases, Forensic aspects of reproductive disorders

Week 10

Forensic aspects of pig diseases, Forensic aspects of poultry diseases

Week 11

Forensic aspects of abuse to animals,

Week 12

Forensic aspects of behavioral problems

Week 13

Expert opinions regarding toxicoses

Week 14

Expert opinions regarding injuries 141

UNIVERSITY OF VETERINARY MEDICINE BUDAPEST

STATE VETERINARY MEDICINE 2 10th Semester Course description Course

State veterinary medicine 2

Department Language

English

Nature

Mandatory

Year/semester

5th year, spring-term

Credits (ECTS)

2

Lectures (hour/semester)

30

Plenary lectures (hour/semester) Practicals (hour/semester)

0

Responsible teacher Teacher(s) Prerequisites

Learning outcome (include skills and competencies, if any) Duties of the veterinarian in the preventiosn and control of notifiable infectious animal diseases

Outcome assessment Written and oral examination where the students can present the complex knowledge on the duties of the veterinarian in the prevention and control of notifiable animal diseases Weekly schedule of lectures and practicals

142

WEEK

Lecture topics

Week 1

Notifiable ruminant diseases I. (Anthrax, Bovine tuberculosis, Bovine brucellosis, Contagious bovine pleuropneumonia

Week 2

Notifiable ruminant diseases II. (Bluetongue; Sheep pox and goat pox, Lumpy skin disease)

Week 3

Foot and mouth disease, Vesicular stomatitis

Week 4

Notifiable rabbit diseases

Week 5

Scabies, Notifiable bee diseases

Week 6

Notifiable equine diseases (African horse sickness; Glanders, Equine infectious anaemia)

Week 7

Notifiable poultry diseases (Newcastle disease, Avian influenza, Duck virus enteritis, Fowl typhoid, Salmonellosis)

Week 8

Notifiable porcine diseases I. (Classical swine fever, African swine fever)

Week 9

Notifiable porcine diseases II. (Swine vesicular disease, Aujeszky-disease, Teschovirus encephalomyelitis)

Week 10

Rabies

Week 11

Spongiform encephalopathies

Week 12

Notifiable fish diseases

Week 13

Enzootic bovine leucosis, IBR

Week 14

Notifiable exotic diseases (Rinderpest, Peste des petits ruminants, Rift Valley fever)

University of Veterinary Medicine Budapest

Istvรกn u. 2, 1078 Budapest, Hungary vetmed@univet.hu +36 1 478 4282 www.univet.hu/en Facebook page: UnivetHU Twitter: UNIVET_Budapest Instagram: univet_budapest YouTube channel: UNIVET BUDAPEST