UH RISES Newsletter July-August 2022

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biostatistician,Ibrahim.resident,formeraspresentationinspirationalonsucceedingaresearchtraineefromUHgeneralsurgeryDr.AndrewOurlead

Anuja Sarode, organized an outstanding comprehensive statistics curriculum using STATA, complete with mock data sets and hands on tutorials. Additional presentation highlights Dr. Amy Rushing’s presentation on Abstract Writing Dr. Chris Towe’s presentation on Generating New Research Dr. Emily Steinhagen’s presentation on Creating Maintaining

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@AndrewMIbrahim

CVs

The UH RISES AIR Program took place from July 11 August 9 with the mission to equip surgical research trainees with the ability to understand research methodology and basic statistics This year’s participation included not only Allen Scholars and Research Fellows from the Department of Surgery, but also trainees from Orthopedic Surgery, Urology, and Neurosurgery. To further aid in their research, laptops and STATA statistical software were provided to our trainees through generous support from Dr. Sabik. Thank you to all of the presenters who helped make this year’s inaugural program a success. The program kicked off with an

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 NEWSLETTER July-August 2022 UH RISES AIR IN THIS ISSUE RISES AIR Recap Research Updates Awards & Accomplishments UH Surgery at ACS Clinical Congress FundingPublications2022OpportunitiesConferenceSchedule UH RISESMEETINGSRESEARCH 2nd and 4th Mondays of each month, 2 4pm 7th Floor Conference Room / Zoom QUICK LINKS Statistical Support Request CONTACT After five weeks of hands on training in clinical research, biostatistics, and professional development, our research trainees are ready to succeed!

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Case Comprehensive Center Retreat – Winter Lab

Congratulations to the Winter Lab on an impressive showing at this year’s Case CCC Annual Scientific Retreat! Three out of the eight total awards presented to trainees in the poster session were won by lab members JJ Hue, MD (PGY3), Omid Hajihassani (CWRU graduate student), and Arian Hajihassani (CWRU undergraduate student). In addition, lab member Ali VaziriGohar, PhD (CWRU post-doctoral scholar), was the only trainee in the entire cancer center invited to present an individual lecture. His presentation, “Wild type IDH1 is required for metabolic rewiring in pancreatic cancer cells under nutrient limitation”, showcased his ongoing exciting research with IDH1 and nutrient availability which was also recently published in Nature Cancer.

Center 2022 Annual Scientific Retreat RESEARCH PRODUCTIVITY - 2022 Make sure your accomplishments are represented Please send updates (accepted abstracts, manuscripts, grant awards) to your UH RISES Division Champion or directly to UHRISES@UHhospitals.org. 6 2 26 15 9 5 7 51 23 3 3 25 7 23 5 3 51 19 4 6 14 1 2 1 0 10 20 30 40 50 60 Surgical Education Bariatric Surgery Cardiac Surgery Colorectal Surgery General Surgery Pediatric Surgery Plastic Surgery Surgical Oncology Thoracic Surgery Transplant Surgery Trauma Surgery Vascular Surgery 2022 Research Productivity by Division Publications Abstracts Grants/Awards

AWARDS & ACCOMPLISHMENTS

Dr. Vaziri Gohar presenting at the Case Cancer

Comprehensive

“Sleeve Gastrectomy Morphology and Weight Loss and Gastroesophageal Reflux Disease Outcomes at Two Years”

 UH SURGERY AT ACS 2022

“Outcomes of Paclitaxel Coated Balloon Angioplasty in Claudication” Session: SP302 6 e Posters IV Station 6: Vascular; 2:30pm 4:00pm

Monday, October 17 Christine Alvarado, MD (PGY3)

“Eliminating Hand Off Handoffs: Improvement in Perioperative Communication with a Multidisciplinary Tool”

“Women Surgical Trainees Interested in Cardiothoracic Surgery Lack Women Cardiothoracic Mentorship”

Session: SP201 1 e Posters III Station 1: General Surgery; 9:45am 11:45am ACS Clinical Congress | Oct 15-20 | San Diego, CA UH Department of Surgery will once again be well represented at this years ACS Clinical Congress 2022 with more than 15 lectures, panels, and research presentations. Please help us support the department’s research program by attending their sessions or checking out their posters. See the attached program for detailed session names, dates, and times of presentations from UH Surgery personnel. Shreya Gupta, MD (PGY5)

Session: SP201 5 e Posters III Station 5: Surgical Oncology; 9:45am 11:15am David Ebertz, MD (PGY4)

Session: SP104 4 e Posters I Station 4: Cardiac/Thoracic Surgery; 9:45am Aria Bassiri, MD (PGY2) “Slipping Rib Syndrome A New Surgical Approach in Pediatric Patients”

“Gastric Bypass Reversal, The Patient’s Journey: An Analysis of Pre-reversal Interventions and Post-reversal Outcomes”

Jonathan Zadeh, MD (Fellow)

Session: SF311 Bariatric/Foregut III; 2:30pm 2:15pm Avkash Patel, MD (PGY3)

Session: SF223 Vascular Surgery II; 2:30pm 4:00pm Rafael Alvarez, MD (Fellow)

Session: SP203 4 e Posters IV Station 4: Bariatric/Foregut; 2:30pm 4:00pm Wednesday, October 19

“Abdominal Aortic Aneurysm Prevalence in Smoking Related Cancers and Sex Differences”

Session: VE104 Pediatric Surgery I; 11:30am 1:00pm Tuesday, October 18 Avanti Badrinathan, MD (PGY2) “General Surgery Emergency: Ambulance or Operating Room?”

“Outcomes of Expedited Joint Radiology Review of Incidental Pancreatic Pathology: A Single Institution Large Series”

Session: SF220 Surgical Education III; 2:30pm 4:00pm Lucy Yang (Medical Student)

Not All Patients With Locally Advanced Rectal Cancer Benefit from Neoadjuvant Therapy. Chang C, Bliggenstorfer JT, Liu J, Shearer J, Dreher P, Bingmer K, Stein SL, Steinhagen E. The American Surgeon. 2022 Jun 18. PMID: 35722940. Diversity Efforts in Surgery: Are We There Yet? Oseni TO, Kelly BN, Pei K, Nielsen M, Pitt SC, Diego E, Mouawad NJ, Stein SL. Am J Surg. 2022 Jul. PMID: Primary35131086.hyperparathyroidism after radioactive iodine therapy: Is it a distinct clinical entity?

RECENT PUBLICATIONS

Bobanga I, Jin J, Wilhelm SM, Sarode A, Alvarado CE, ElSharif A, McHenry CR. American Journal of Surgery. 2022 Jul 31. PMID: 359354557. Evolution of intra operative parathyroid hormone and its application in parathyroid surgery Machado NM, Wilhelm SM. Vitamins and Hormones. 2022. PMID: 35953113. Establishing National Stakeholder Priorities for Quality Improvement in Pediatric Trauma Care: Consensus Results Using a Modified Delphi Process Melhado CG, Yorkgitis BK, Patel B, Remick K, Macias CG, Dingeldein MW, Gray L, Jensen AR. Journal of Trauma and Acute Care Surgery. 2022 Jun 17. PMID: Clear35713930.cellsarcoma of the anterior chest wall. Pei E, Saab S, Stearns D, Miyasaka EA. Journal of Pediatric Surgery Case Reports. 2022 Jun. Identifying Risk Factors and Advancing Services for Violently Injured Low Income Black Youth. Voith LA, Atwell MS, Sorensen A, Thomas TJ, Coulton C, Barksdale EM Jr. Journal of Racial and Ethnic Health Disparities. 2022 Jul 11. PMID: 35819721. The Orbital Index: a novel comprehensive quantitative tool for prediction of delayed enophthalmos in orbital floor fracture management. DeRuiter BJ, Kotha VS, Lalezar FD, Swanson MA, Kumar MA, Barmettler A, Prendes MA, Davidson EH. Plastic and Reconstructive Surgery. 2022 Jul 1. PMID: 35791257.

Anticoagulation in New Onset Postoperative Atrial Fibrilation: An Analysis from the Society of Thoracic Surgeons Adult Cardiac Surgery Database. Riad FS, Grau Sepulveda M, Jawitz OK, Vekstein AM, Sundaram V, Sahadevan J, Habib RH, Jacobs JP, O’Brien S, Thourani VH, Vemulapalli S, Xian Y, Waldo AL, Sabik JF 3rd. Heart Rhythm O2. 2022 Jun Surgical15. aortic valve replacement with a stented pericardial bioprosthesis: 5 year outcomes. Klautz RJM, Dagenais F, Reardon MJ, Lange R, Moront MG, Labrousse L, Weissman NJ, Rao V, Patel HJ, Liu F, Sabik JF, PERIGON Investigators. European Journal of Cardiothoracic Surgery. 2022 Jul 5. PMID: Comparison35789382.ofHemodynamic Performance of Transcatheter Aortic Valve Implementation With Supra Annular Self Expanding Versus Balloon Expandable Valves Assessed by Exercise Cardiovascular Magnetic Resonance Attizzani GF, Palma Dallan LA, Yoon SH, Feroze R, Rajagopalan V, Baeza C, Pelletier MP, Al Kindi S, Rajagopalan S, Rashid I. American Journal of Cardiology. 2022 Jul 14. PMID: 35842277. Cost Effectiveness of Percutaneous Coronary Intervention Versus Bypass Surgery for Patients with Left Main Disease: Results from the EXCEL Trial. Magnuson EA, Chinnakondepelli K, Vilain K, Serruys PW, Sabik JF, Kappetein AP, Stone GW, Cohen DJ, EXCEL Investigators. Circulation: Cardiovascular Interventions. 2022 Jul. PMID: Percutaneous35861797. mechanical thrombectomy and extracorporeal membranous oxygenation: A case series. Mously H, Hajjari J, Chami T, Hammad T, Schliz R, Carman T, Elgudin Y, Abu Omar Y, Pelletier MP, Shishehbor MH, Li J. European Journal of Cardiothoracic Surgery. 2022 Aug. PMID: 35686535. The time varying cardiovascular benefits of glucagon like peptide 1 receptor agonist therapy in patients with type 2 Diabetes Mellitus: Evidence from large multinational trials. Deo SV, Marsia S, McAllister DA, Elgudin Y, Sattar N, Pell JP. Diabetes Obesity and Metabolism. 2022 Aug. PMID: 35491516.

A comparison of robotic and laparoscopic minimally invasive adrenalectomy for adrenal malignancies Hue JJ, Ahorukomeye P, Bingmer K, Drapalik L, Wilhelm SM, Rothermel LD, Towe CW. Surgical Endoscopy. 2022 Jul. PMID: 34724582. Monitoring for Recurrence Following Esophagectomy. Chang C, Linden PA, Jiang B, Sarode A, Bachman K, Towe CW, Argote Green L, Worrell SG. Annals of Thoracic Surgery. 2022 Jul. PMID: Radiomics34793795.tothe Rescue. Annals of Surgical Oncology. Towe CW. 2022 Jul 16. PMID: 35842536. Surgical Repair Versus Stent for Esophageal Perforation: A Multi Institutional Database Analysis. Gray KE, Sarode AL, Jiang B, Alvarado CE, Sinopoli J, Linden PA, Worrell SG, Ho VP, ArgoteGreen LM, Towe CW. Annals of Thoracic Surgery. 2022 Jul 31. PMID: 35921860. Impact of Interfacility Transfer of Ruptured Abdominal Aortic Aneurysm Patients. Lim S, Kwan S, Colvard BD, d’Audiffret A, Kashyap VS, Cho JS. Journal of Vascular Surgery. 2022 Jun 22. PMID: Outcomes35752382. of Great Vessel Debranching to Facilitate Thoracic Endovascular Aortic Repair Patel AJ, Ambani RN, Sarode AL, King AH, Baeza CR, Elgudin Y, Colvard BD, Kumins NH, Kashyap VS, Sabik JF, Cho JS. Journal of Vascular Surgery. 2022 Jul. PMID: 35149157.

ASO Author Reflections: Inflammatory Breast Cancer: The Exception to De escalation of Care for Older Women? Drapalik LM, Amin AL, Miller ME. Annals of Surgical Oncology. 2022 Aug 5. PMID: 35930106.

RECENT PUBLICATIONS 

Prodromal depression and anxiety are associated with worse treatment compliance and survival among patients with pancreatic cancer. Davis NE, Hue JJ, Kyasaram RK, Elshami M, Graor HJ, Zarei M, Ji K, Katayama ES, Hajihassani O, Loftus AW, Shanahan J, Vaziri-Gohar A, Rothermel LD, Winter JM Psychooncology. 2022 Aug. PMID: 35470512.

Impact of a Virtual Professional Development Coaching Program on the Professional Fulfillment and Well-Bring of Women Surgery Residents: A Randomized Controlled Trial. Palamara K, McKinley SK, Chu JT, Merrill A, Yu L, Parangi S, Makowski MS, Donelan K, Stein SL. Annals of Surgery. 2022 Jun 29. PMID: 35766397. A Comparison of Faculty and Resident Perceptions on the Qualities of Outstanding Surgical Educators. Sharma N, Steinhagen E, Marks J, Ammori J. Journal of Surgical Education. 2022 Aug 3. PMID: 35933310 Assessing the Use of Extended Venous Thromboembolism Prophylaxis on the Rates of Venous Thromboembolism and Post pancreatectomy Hemorrhage Following Pancreatectomy for Malignancy. Stitzel HJ, Hue JJ, Elshami E, McCaulley L, Hoehn RS, Rothermel LD, Ammori JB, Hardacre JM, Winter JM, Ocuin LM. Annals of Surgery. 2022 Jul 7. PMID: 35797622. Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors. Vaziri Gohar A, …Zarei M, Hue JJ, Hajihassani O, Graor HJ, … Wang R, Rothermel LD, …Winter JM. Nature Cancer. 2022 Jul. PMID: 35681100. Mucosal melanoma and organ specific metastasis: Differences in survival outcomes between tumor primary sites. Mulligan KM, Culison CR, Zheng DX, Rothermel LD, Levoska MA, Scott JF. Journal of the American Academy of Dermatology. 2022 Jul 5. PMID: 35803400. Time to Neoadjuvant Chemotherapy Initiation if not Associated With Survival in Pancreatic Cancer. Hue JJ, Sugumar K, Elshami E. Rothermel LD, Ammori JB, Hardacre JM, Winter JM, Ocuin LM Journal of Surgical Research. 2022 Aug. PMID: Age35436663.disparities in triple-negative breast cancer treatment and outcomes: An NCDB analysis. Drapalik LM, Estes A, Sarode AL, Cao L, Shenk RR, Jarrett CM, Amin AL, Miller ME. Surgery. 2022 Aug 1. PMID: 35927082.

AAS/AASF Global Surgery Research Fellowship Award Association for Academic Surgery (AAS) Award Amount: $30,000/1 year Application Deadline: 9/1/2022 More Information AAS/AASF Trainee Research Fellowship Award –Basic Science/Translational Research Association for Academic Surgery Award Amount: $30,000/1 year Application Deadline: 9/1/2022 More Information Systems for Action (S4A) Research Program Robert Wood Johnson Foundation Award Amount: Developmental Studies up to $100,000/1 year; Impact Studies up to $500,000/3 years Application Deadline: 9/6/2022 (LOI), 10/5/2022 (Application) More Information TSF Research Award Thoracic Surgery Foundation Award Amount: $85,000/yr; 2 years Application Deadline: 9/15/2022 More Information STS Research Award Thoracic Surgery Foundation Award Amount: $90,000/yr’ 2 years Application Deadline: 9/15/2022 More Information AstraZeneca Reversing Health Disparities in Lung Cancer Research Award Thoracic Surgery Foundation Award Amount: $50,000/yr; 2 years Application Deadline: 9/15/2022 More Information Research, Equity, Diversity & Inclusion (REDI) Pilot Funding Research Opportunity Theme Pilot CTSC Award Amount: $15 25k Application Deadline: 9/30/2022 More Information FUNDING OPPORTUNITIES SURGICAL CONFERENCE SCHEDULE CREF 2022 41st Cardiothoracic Surgery Symposium Cardiothoracic Research and Education Forum October 19 23, 2022 | San Diego, CA Abstract Deadline: 9/2/2022 VENOUS2023 American Venous Forum February 22 25, 2023 | San Antonio, TX Abstract Deadline: 9/12/2022 23rd Annual ASTS Winter Symposium American Society of Transplant Surgeons January 12 15, 2023 | Miami, FL Abstract Deadline: 9/12/2022 2023 Annual ACS Surgical Simulation Summit American College of Surgeons March 2 4, 2023 | Chicago, IL Abstract Deadline: 9/13/2022 18th Annual Academic Surgical Congress Association for Academic Surgery February 7 9, 2023 | Houston, TX Abstract Deadline: 9/19/2022 ACC.23 (with World Congress of Cardiology) American College of Cardiology March 4 6, 2023 | New Orleans, LA Abstract Deadline: 9/22/2022 SAGES 2023 Society of American Gastrointestinal and Endoscopic Surgeons March 29 April 1, 2023 | Montreal, Canada Abstract Deadline: 9/23/2022 

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