INVIVO DIAGNOSTICS LTD

We've grown accustomed to hearing about 'good bacteria' in yogurt commercials on the TV. But which bacteria are good, which are bad, and do elevated levels mean there's something seriously wrong with us?

Since 2018 Invivo Diagnostics has been working to analyse microbiome samples taken from patients and build a wide picture of what our internal microbial ecosystems can and should look like.

Meanwhile, its sister company Invivo Healthcare produces supplements that can rebalance our microbial ecosystems when there is a deficit of 'good bacteria'.

From its lab in Bristol, Invivo concentrates on three main areas: vaginal, oral, and gastrointestinal microbiomes. Tests are submitted by clinicians for diagnosis.

The presence of certain bacteria can explain illnesses or medical conditions – irritable bowel syndrome, for example. And they can also provide markers in the diagnosis of cancers.

Invivo's scientists are also keen to understand the bigger patient picture. Stress, smoking, diet and chemicals like perfumes can all affect microbial ecosystems, as can the PH levels – the acidity – of the mouth, stomach or vagina. Founder Humphrey Bacchus says it is important to understand "the soup in which the bacteria are swimming".

Understanding the way human microbiomes interact with each other could prevent conditions like infertility and miscarriages. Looking at how a man’s semen microbiome and his partner’s vaginal microbiome react with each other could help women conceive more successfully and carry a baby to full term, says the company.