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Texas Biomed Annual Report 2018

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Board of

TRUSTEES EXECUTIVE COMMITTEE Dr. James (Jamo) Rubin, Chairman

Mr. John R. (J.R.) Hurd

Chief Executive Officer, TAVHealth

Chair, Hurd Enterprises, Ltd.

Dr. C. Collins (Andy) Anderson III, Vice Chairman

Mrs. Abigail G. Kampmann

Managing Partner, Windgate Partners, LLC

Chief Executive Officer, Principle Auto

Mr. James B. (Jamie) Smith, Secretary

Mr. John C. Kerr

Vice Chairman – Texas, Dykema Cox Smith

Mr. Richard T. (Dick) Schlosberg III (Retired) Publisher and CEO, Los Angeles Times

Mrs. Marsha M. Shields Manager, McCombs Family Partners, Ltd.

Principal, Moorman Kerr Interests

Dr. James (Jamo) Rubin Chairman

TRUSTEES Mr. Rex Amini Managing Director, Sage Energy Co.

Mr. Edward H. Austin, Jr. Principal, Austin Family Investments

Mr. Richard N. Azar II General Partner, Sezar Energy, L.P.

Mr. Craig Boyan President & Chief Operating Officer, H-E-B

Mr. Robert M. (Bobby) Cavender President, Cavender Auto Group

Ms. Phyllis Slick Cowell President, Slick Enterprises

Mrs. Barbara B. Dreeben Mr. Walter Embrey Chief Executive Officer, Embrey Partners, Ltd.

Mr. John W. Feik Chief Executive Officer, Feik Enterprises, LLC

Mr. Richard Kardys (Retired) Wealth Advisor Senior Officer, Frost Bank

SPECIAL TRUSTEES

TRUSTEES EMERITUS

Mr. Adam L. Hamilton

Dr. Ronald K. Calgaard

President & CEO, Southwest Research Institute

Mr. William R. (Bill) Klesse

Dr. Taylor Eighmy President, UTSA

Mrs. Carolyn H. Labatt

Dr. Andrea Giuffrida

Chief Executive Officer, Computer Solutions

(on behalf of Dr. William L. Henrich)

Vice President for Research and Professor, UTHealth San Antonio

Mr. Mark Pitman Mays Principal, Rocking M Capital

Mr. Joe C. McKinney

EX-OFFICIO TRUSTEE

Vice Chairman, Broadway National Bank

Ms. Callie Price President, Founder’s Council

Mr. Lewis J. (Lew) Moorman IV

Mr. Al Philip

Entrepreneur

President, The Argyle

Dr. Dacia Napier

Ms. Jody Lutz

Radiologist

President, Texas Biomedical Forum

Mr. Charles (Chuck) Urschel Slick Partner, Slick Enterprises

HONORARY TRUSTEE

Mr. John B. Zachry

Dr. John P. Howe, III

Chairman and CEO, Zachry Group

Retired President/CEO, Project HOPE

Mrs. Ashley Hixon

Hixon Family Office 2

Chairman, Ray Ellison Grandchildren Trust, The Abbey

Mr. James W. Gorman, Jr. Investor/Rancher

Mr. William E. Greehey Chairman, NuStar Energy, L.P.

Mr. Milton B. Lee (Retired) CEO, CPS Energy

Mr. B.J. McCombs Chairman, McCombs Enterprises

Mr. William G. (Bill) Moll (Retired) CEO, KLRN (Retired) Chairman & CEO, Clear Channel Television

Mr. Edward E. Whitacre, Jr. Chairman Emeritus, AT&T


Table of

CONTENTS 4 6 12 16 18 19 20 22 23 27 29 32 3

PRESIDENT’S LETTER

CHANGING LIVES IMPACTED BY INFECTION

DEEPAK KAUSHAL, NEW DIRECTOR OF THE SNPRC

COMMUNITY OUTREACH: BUILDING A CITY OF SCIENCE

ASSEMBLING THE FUTURE

FINANCIALS

GRANTS AND CONTRACTS

TEXAS BIOMED CONTRIBUTIONS

CIRCLES OF GIVING

TEXAS BIOMED FORUM

THE FOUNDER’S COUNCIL

THE ARGYLE


From the

PRESIDENT Fighting Infection TEXAS BIOMED’S NORTH STAR

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talent and resources into supporting the entire research pipeline from early stage discovery through to diagnostics, therapies and cures for the benefit of mankind. This legacy continues.

sed as a noun, the word focus means “an act of concentrating interest or activity on something.” Last year, Texas Biomedical Research Institute defined its scientific area of focus as infectious diseases and hired new talent, created new science and outreach programs and launched our campus transformation projects as part of our bold, 10-year strategic plan.

Author and businessman Zig Ziglar once said, “I don’t care how much power, brilliance or energy you have, if you don’t harness it and focus it on a specific target, and hold it there you’re never going to accomplish as much as your ability warrants.”

According to the World Health Organization, half-a-million cases of drug resistant TB are reported annually. Every minute, a teenage girl in sub-Saharan Africa gets HIV. In 2017, 210 million people were stricken with malaria; 1/3 of surgical patients get a postoperative infection; 51% can be antibiotic resistant “superbugs.” Sepsis accounts for more than 50% of hospital deaths in the United States according to a December 2018 study published in the journal “Critical Care Medicine.” We are currently suffering from the largest number of cases of measles in 25 years. Finally, we have increasing susceptible populations, especially the elderly and those with diabetes. More and more, we are finding links between infection and diseases like heart disease, cancer and Alzheimer’s.

Texas Biomed’s foundational mission calls for us to harness our power of discovery and direct it. Since its founding in 1941 by Thomas B. Slick, Jr., the Institute has been putting its energy, time,

Texas Biomed’s mission is to innovate and share scientific breakthroughs to protect you, your families and our global community from infectious diseases. We do that by identifying

This focus has bolstered attention on the global challenges of infectious diseases and on the solutions Texas Biomed offers to meet these challenges.

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and solving these problems faster and smarter than anybody else. Our uniqueness lies in our vision, our people and our business practices. We have combined assets and expertise on one campus that can’t be found elsewhere in the world; we are vertically integrated in our approach to science from bench to bedside, and we are a nonprofit that runs much like a for profit business — nimble and fast. This approach is by design, so we can accomplish science more efficiently and effectively with greater attention on the benefit to mankind. In this year’s annual report, we outline specific programmatic resources we are dedicating to our mission, new scientists we have added to our growing research team, campus-wide renovation projects aimed at equipping our scientists with the latest and greatest assets, as well as new programs we have begun to help educate our community and the next generation of scientists. San Antonio is a unique city in which to work thanks to its pioneering spirit, its history and the generosity of the community. This community’s support is critical to our future growth and success, because the community — each of you — is why we exist. As always, we appreciate your continued partnership and backing as we execute our mission. Science contributes to our understanding of the world around us; it provides comfort and makes life easier; it is a means to an end… better lives for generation after generation. Texas Biomed’s focus and the transformation it is undergoing underscores the commitment and dedication our team has to accomplishing the goal of enhancing lives through discovery.

Larry Schlesinger, M.D. President and CEO

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Janeli Castrejana with her husband Jacob and three children.


Changing Lives

IMPACTED BY INFECTION

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ornings are busy at the Castrejana household. With three children to cart to school before she heads to work, Janeli Castrejana has gotten good at multitasking. The 30-year-old San Antonian always dreamed of becoming a mother. A health crisis in her early 20s could have robbed her of having a family.

Thanks to compassionate caregivers and breakthroughs in scientific research, the HIV virus is undetectable in Janeli’s system. Janeli is not cured, but she controls her disease with medications. She became a parent without transmitting the virus to her unborn babies. “It felt like a miracle,” Janeli added.

Janeli contracted HIV, the virus that causes AIDS, when she was only 21. “I was devastated,” she said. “I thought my life was over. I thought I was going to die.”

Infectious diseases of many varieties are on the rise. The World Health Organization reports infectious diseases kill more than 17 million people a year. Thirty new diseases have emerged in the last 20 years.

2018 saw some amazing strides in the fight against infectious diseases, some of which were made by our scientists at Texas Biomed. For example, Professor Jean Patterson, Ph.D. and Professor Suzette Tardif, Ph.D., took part in a collaborative study that demonstrated the Zika virus may be triggering miscarriages and stillbirths while going undetected.

The enemies are stealthy — viruses, bacteria, fungi, parasites. They infect. They spread. They evolve. Science must keep up.

Tuberculosis (TB) researchers Dr. Schlesinger and Staff Scientist Eusondia Arnett, Ph.D., found promising experimental cancer

The AIDS epidemic has killed 35 million people since it began in the 1980s. More than 40 million people in the world are infected with HIV today.

THE FIGHT IS UNDERWAY

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“Combating infectious diseases is one of the most important health issues of our time,” said President/CEO Larry Schlesinger, M.D. “While research has helped stop the spread of many infectious pathogens and reduced human suffering, science still has a long way to go to conquer these serious health threats.”


chemotherapy drugs may help knock out TB. Teaming up with a commercial biopharmaceutical company, Texas Biomed scientists are helping test a promising treatment for Ebola virus. Our specialists in malaria are working to find out why the mosquito-borne parasites that cause the disease are becoming drug resistant. “2018 was a strong year with regard to grant and contract submissions and awards, groundbreaking research, and high impact publications from our faculty at Texas Biomed,” said Professor and Vice President for Research Joanne Turner, Ph.D. Using our population of nearly 2,500 animals at the Southwest National Primate Research Center on campus, scientists are developing new models for liver cancer, testing an experimental hepatitis B vaccine and scanning the brains of baboons to help pinpoint a biomarker for mental illness. Our researchers have developed the marmoset as a new and crucial animal model to study aging and infectious disease.

FOCUS ON THE FUTURE In 2018, Texas Biomed built on its strengths and focused on the future with a new 10-year

AS OUR POPULATION AGES AND OTHER CHRONIC CONDITIONS LIKE DIABETES COMPLICATE HEALTH ISSUES, MORE PEOPLE WILL HAVE WEAKER IMMUNE RESPONSES TO FIGHT OFF THESE BURGEONING HEALTH THREATS.

Strategic Plan. This plan has become the Institute’s road map for growth. The plan includes the expansion of research to include other threatening infectious diseases impacting human health. Common hospital infections like MRSA and sepsis kill thousands of men and women before their time. Food-borne illnesses cause untold suffering. The dream for a better influenza vaccine is still unrealized. As our population ages and other chronic conditions like diabetes complicate health issues, more people will have weaker immune responses to fight off these burgeoning health threats. A recent report commissioned by Texas Biomed from economic development researcher TEConomy concluded “basic

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science is where key developments in infectious disease innovation will continue occurring for the foreseeable future.” We have begun the process of recruiting new teams of top tier scientists and their research groups with complementary expertise dedicated to collaborative scientific research. As part of our focus, we’ve created three inter-related scientific programs: Host Pathogen Interaction, Disease Intervention & Prevention and Population Health. The Host Pathogen Interaction program focuses on the biology of infection and the relationship between the body and the pathogen. Program Lead and Assistant Professor Ian Cheeseman, Ph.D., explained the three new growth areas within this program include the study of vectors (like


(l to r) Ricardo Carrion, Jr., Ph.D., Program Co-lead; Shelley A. Cole, Ph.D., Program Co-lead; Jordi Torrelles, Ph.D., Program Lead; Ian Cheeseman, Ph.D., Program Lead; Luis Giavedoni, Ph.D., Program Co-lead; Timothy Anderson, Ph.D., Program Lead

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A 3-D rendering of HIV virus in the blood stream. Acquired immunodeficiency syndrome (AIDS) is a chronic, potentially life-threatening condition caused by the human immunodeficiency virus (HIV).


mosquitoes) that carry disease, mucosal immunology (areas of attachment of pathogen) and developing and using new models of infectious diseases. “To identify the next major discoveries which transform human health, we need a better fundamental understanding of how a disease is controlled by a host, transmitted by a vector or exacerbated by a pathogen,” Dr. Cheeseman said. “This requires a multipronged approach where we build realistic models of infection combining animal and laboratory methods, probe the sites of invasion and infection in the human body and study the genetic variation in the hosts, pathogens and vectors driving disease outcomes.” The Disease Intervention and Prevention program focuses on the development of new ways to diagnose, treat and vaccinate against diseases to reduce the effects of the illness or cure it. Program Co-lead and Professor Ricardo Carrion, Jr., Ph.D. said this program will grow in areas related to multi-drug resistance and hospital-acquired infections, experimental diagnostics and therapeutics and next generation vaccines. “The Disease Intervention and Prevention program provides an environment that fosters collaboration and synergy within

the Institute’s current research areas of vaccine and therapeutic development, while spurring research in new growth areas such as multidrug resistant pathogens and hospital-acquired infections,” Dr. Carrion explained. “The critical mass of scientists working alongside each other in these fields in an atmosphere that strives for excellence will bolster Texas Biomed as a leader in infectious disease research.” Population Health will focus on how factors like DNA, age, nutrition and co-infections impact susceptibility to disease. Program Co-lead and Associate Professor Shelley Cole, Ph.D., outlined the three growth areas of this program as how the genes of individuals in a population may increase their susceptibility to infection, risk of infection due to other health conditions and the role the environment plays in the development of infectious diseases. “Population Health is a key component of biomedical research in that population health studies are used to define problems of public health importance, to determine and characterize potential causes and modifiers of a disease in the population and to demonstrate the effectiveness of prevention and intervention approaches,” Dr. Cole said.

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To create an environment where these scientific programs can flourish — and to accommodate our growing team — plans have been laid out for structural changes that will enable the expansion of our staff and update the aging campus. Some of the construction is well underway, as highlighted on page 18.

SCIENCE GIVES US A FUTURE For millions of people around the world like Janeli Castrejana, Texas Biomed’s focus on infectious diseases is a source of hope for the future. “I am eternally grateful to the researchers who work tirelessly on new therapeutics for HIV-positive patients,” she says. “Because of them, I am the mother of three HIVnegative children.” 77 years ago, the bold founder of Texas Biomed, Tom Slick, Jr., had a vision. He believed “the welfare of mankind can be best advanced through the scientific endeavor.” The power of discovery through focused biomedical research will improve the human condition. Our focus honors Slick’s vision.


Deepak Kaushal, Ph.D.

NEW DIRECTOR OF THE SNPRC

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eepak Kaushal, Ph.D., is a Professor at Texas Biomedical Research Institute and the new Director of the Southwest National Primate Research Center (SNPRC). He oversees the SNPRC operations, a more than $40 million National Institutes of Health-funded national resource for primate research. Dr. Kaushal is also one of the top most-funded researchers by the NIH in the United States. His research focuses on tuberculosis (TB), a disease that claims two million lives a year. Although Dr. Kaushal’s list of achievements and contributions to research are impressive, a career in the lab wasn’t always his dream. In fact, Dr. Kaushal once saw himself attending medical school after earning his undergraduate degree. Instead, he decided to pursue a master’s degree in Biochemistry at

the University of Delhi in India, his home country. During his master’s program, Dr. Kaushal was introduced to a group of young, driven scientists who had just come back from their research training in the United States. He was inspired by their intellectual curiosity and dedication to research. It was this connection that inspired Dr. Kaushal to consider a future in the lab.

Upon graduating, he became a Fogarty Foundation International Post-doctoral fellow at the Johns Hopkins University School of Medicine Center for Tuberculosis Research. Dr. Kaushal chose to focus his research on TB because he enjoyed the challenge of combating the number one infectious disease killer in the world. He remains determined to find a vaccine or set of drugs to control transmission of TB.

BECOMING A SCIENTIST

“If you look at how many people TB has killed over the course of human history versus how many people malaria has killed, or AIDS, or syphilis and you put all of these deaths together, TB has killed a thousand-fold more people in the history of mankind,” Dr. Kaushal said.

Dr. Kaushal pursued his newfound interest in research by earning his Ph.D. in Biochemistry at the University of Delhi.

In 2001, Dr. Kaushal took his passion for TB research to St. Jude Children’s Research Hospital Center for Bioinformatics and

“They had very dynamic and different views about how to conduct research,” Dr. Kaushal said. “Their viewpoints encouraged me, and I found my niche.”

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Biotechnology. Then in 2006, Dr. Kaushal moved to Louisiana to accept a faculty position at the Tulane National Primate Research Center, where he advanced his research through the use of nonhuman primate models. Throughout his 13 years at Tulane University, Dr. Kaushal rose through the ranks to become the Director of the Tulane Center for TB Research and a Professor of Microbiology & Immunology.

A NEW PLACE TO CALL HOME While Dr. Kaushal enjoyed his time in the university environment, he craved a new challenge. He wanted to provide more leadership while continuing to mentor others and advance his research. When TB researcher Larry Schlesinger, M.D., became the new President and CEO of Texas Biomed in 2017, Dr. Kaushal started to consider moving his lab to San Antonio. With Dr. Schlesinger’s support and the construction of a new 7,500 square foot facility complete with a Biosafety Level-3 (BSL-3) lab where TB research can be safely conducted, Dr. Kaushal decided to make Texas Biomed his new home in the fall of 2018. His position as Director of the SNPRC gave him the leadership opportunity he was looking for.

(l to r) Shashank Ganatra, M.B.B.S., Riti Sharan, Ph.D., Tae Hyung Lee, Ph.D., Ayan Chatterjee, Ph.D., Deepak Kaushal, Ph.D., Dhiraj Singh, Ph.D., Alyssa Blakley, Danicke Willemse, Ph.D., Abigail Fish, Ph.D. “I have uninterrupted energy and enthusiasm for the job,” Dr. Kaushal said. “I think the previous director Dr. Robert Lanford has done a fantastic job of leading the SNPRC, and I think I have the initiative and vision to continue this growth.” Additionally, the SNPRC’s diverse population of nonhuman primates opened the door for new research opportunities for Dr. Kaushal. At Tulane University, Dr. Kaushal primarily worked with rhesus

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macaques. At the SNPRC, he has the chance to use marmosets, baboons, and other species of macaques as animal models to investigate various concepts of TB. The research opportunities at Texas Biomed and the SNPRC was also appealing to Dr. Kaushal’s research team, including Dr. Dhiraj Kumar Singh, a postdoctoral scientist who followed Dr. Kaushal from Tulane University. However, the potential for research advancements wasn’t the only


appealing aspect of continuing to work with Dr. Kaushal. “Dr. Kaushal sees more talent in us than we see in ourselves,” Dr. Singh said. “He provides all the mentoring, support and motivation needed to push us to our peak performance, enabling us to excel in all dimensions of life, professional and personal alike. Who would not want to learn and be trained by such a wonderful mentor? Henceforth, when provided with the opportunity to follow Dr. Kaushal to Texas Biomed, I didn’t give it a second thought.”

animal husbandry and customer service. Dr. Schlesinger believes Dr. Kaushal is a skilled scientist who can achieve this goal. “The primate center is a flagship enterprise here at Texas Biomed,” Dr. Schlesinger said. “I was looking for a dynamic leader with great ideas and the desire to continue to elevate the stature of the primate center both nationally and internationally. Deepak is a great fit and has hit the ground running. He is a fabulous scientist and a strong leader.” When Dr. Kaushal isn’t in the lab or office, he is with his family. Dr. Kaushal is a proud

FUTURE GOALS With the incredible teamwork, integrity and diversity of Texas Biomed, Dr. Kaushal sees potential for growth at the Institute and the SNPRC. For example, he hopes to obtain more transformative technologies, such as the recently acquired endoscope, so researchers at Texas Biomed can continue to advance their infectious disease research without having to consult outside sources. He also sees a future with more collaborative opportunities with scientists in and outside Texas Biomed.

Tuberculosis infection inside the lung.

However, Dr. Kaushal’s ultimate goal is to be “known as the best NPRC” when it comes to cost-effectiveness, safety,

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husband and father of two children who are both in high school. He has diverse interests in culture, music and the arts and even enjoys a cricket game every once in a while. Texas Biomed and the SNPRC are proud to be the new home of one of the most outstanding and dedicated TB researchers in the nation. “We look forward to more extraordinary scientific discoveries and continued growth of the SNPRC,” Dr. Schlesinger said. “We are lucky to have a multi-talented scientist such as Dr. Kaushal.”


Community Outreach

BUILDING A “CITY OF SCIENCE”

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s today’s research leaders at Texas Biomedical Research Institute work to diminish the threat of infectious diseases, Texas Biomed’s community outreach program educates tomorrow’s scientists who will continue this good work.

said Kelli Oberheu, Science Department Chair and Biomedical Science Teacher of Harmony Public School. “Being able to talk with individuals doing research and those working with the animals was very exciting. I love that the students are so interested in science and the research that is happening so close to them.”

Texas Biomed has expanded its community outreach efforts in various ways. Since March 2018, we have successfully doubled tours for high schools, college groups and businesses. These tours include educational presentations from scientists, veterinarians and other professionals across campus, as well as a virtual tour of our Biosafety Level-4 laboratory and an up close look at the nonhuman primates in the Southwest National Primate Research Center. These tours impacted more than 1,000 visitors in 2018, including hundreds of local students.

Texas Biomed has made significant strides to develop more STEM (Science, Technology, Engineering, and Math) partnerships in the community with outreach to business and educational groups and even arts organizations. At science fairs, students are taught the importance of animal research from animal caretakers, and they learn about the various pathogens our scientists work with through hands-on activities.

“Our connection with Texas Biomed has been extremely inspirational to our students,”

“At Girls Inc, we work every day to connect young girls to local STEM professionals so that they can see all of the amazing opportunities available for them,” said Heather Aguillon, STEM Program Manager

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for Girls Inc. of San Antonio. “Being able to engage with industry partners like Texas Biomed is a great way for kids to meet, talk to and work with someone who just might change the trajectory of their life.” Other projects have included coordinating with local organizations such as The Public Theater of San Antonio. The Public Theatre hosted a special night for Texas Biomed at its Spring showing of Rent, a Broadway musical focused on those suffering from HIV at the height of the epidemic. The evening included an audience discussion after the performance with representatives from Texas Biomed, The Public Theater and the San Antonio AIDS Foundation. “The partnership with Texas Biomed and The Public Theater has exceeded my expectations,” added Shelly Chance, Chief Operating Officer and Managing Director of the San Antonio Public Theatre. “It is wonderful for the theater to start a conversation about science and have the expertise of scientists to elevate


the conversation with real time research and progress. I am so impressed with Texas Biomed’s work, growth, and dedication to ensuring the world is a healthier place for all of us. The campus is warm and inviting, and it is vividly clear everyone performs their jobs with great care and dignity.” Community outreach is a perpetual effort to foster awareness and engagement. Ultimately, outreach efforts are a way to connect our community with science and foster an appreciation for and a desire to pursue science education. Expansion of our outreach efforts is critical to the Institute’s overall growth. Through community outreach projects, we reach thousands of innovative minds that may hold the key to the next scientific breakthrough. As we look to the future, Texas Biomed is undoubtedly becoming a critical partner in San Antonio’s STEM ecosystem to build a “City of Science.”

Texas Biomed has participated in Girls, Inc.’s RockIt Into the Future Science Festival for two years, bringing biomedical research to our next generation of scientists.

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ASSEMBLING THE FUTURE

C

hange is in the air on the Texas Biomed campus. Three large construction projects consumed the Operations Team in 2018. Each of these improvements creates laboratory and animal space that allows for continued growth of our scientific endeavors.

NEW BSL-3 LABORATORY The new Biosafety Level-3 (BSL-3) laboratory opening Summer 2019 includes 7,500 square feet of space. Assistant Vice President for Operations, Matt Majors, describes it as “an exciting lab. This is the first of its kind for Texas Biomed, and there are very few labs like this in the country. We’re making major investments to improve efficiency, effectiveness, and customer service.” BSL-3 laboratories are high containment spaces where scientists work on communicable diseases that are serious and transmittable, but treatable, like tuberculosis. The facility will hold several new technologies Texas Biomed has not had before, like an aerosol biology room to mimic natural paths of infection with pathogens, a PET CT room,

a necropsy suite, and a huge autoclave which sterilizes equipment and cages. With so much space, the new BSL-3 will be able to house up to 80 nonhuman primates and 2,500 mice. The facility will also have amenities for the scientists including showers and a changing room. “This state-of-the-art BSL-3 facility will provide Texas Biomed researchers and collaborators with a unique platform to test novel therapies and vaccines against deadly infectious diseases such as tuberculosis, explained Professor Jordi Torrelles, Ph.D., BSL-3 Director. “With capacity to hold 25 researchers working at once and a large and diverse number of animals (mice, marmosets, macaques, baboons), this facility will provide unique venues for contract studies and foster new collaborations within San Antonio and with the U.S. and global scientific community.”

NEW MARMOSET HOUSING The James R. Dougherty, Jr., (JRD) Medical Research Laboratory has been converted into updated, expanded space for the Southwest National Primate Research Center’s colony

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Texas Biomed’s new BSL-3 is set to open summer 2019, providing scientists new state-of-the-art equipment and facilities. of marmosets. These are small New World monkeys that serve as important animal models for aging and infectious disease studies. The interior renovation of the JRD building is a $2.5 million investment. Much of the work is mechanical. At full capacity, this 12,000 square foot building can house up to 550 marmosets, and will start with 450 marmosets, making it the country’s largest captive colony of these monkeys dedicated to biomedical research. “The construction and improvement of the JRD building will enhance the care and housing capacity for the marmosets, providing specialized barrier space to care for geriatric marmosets, and a new dedicated cage wash,” explained Associate Professor Corinna Ross, Ph.D., of the SNPRC. “These


FINANCIALS 2018 REVENUE

2018 VALUE OF ENDOWMENT

BASED ON 2018 AUDITED REPORT*

IN MILLIONS OF DOLLARS 58.1% Federal Grants 1.6%

$130

Non-Federal Grants

$125.1 $117.4 $118.3

$120

$111.5

$114.6 $107.2

17.5% Federal Contracts $100.8

$100 $93.2

5.1%

Commercial Contracts

0.8% 8.9%

Non-Federal Contracts Restricted Contributions

5.2% 2.5% 0.3%

Unrestricted Contributions Royalty Income Other Income

$91.4

$80

$60

2010

2011

2012

2013

2014

2015

2016

2017 2018

* Compared to years past, revenue excludes investment income due to market decline at the end of 2018. With the market rebound in 2019, investment income and endowment value have both increased.

facilities will help SNPRC meet the needs of the national marmoset research community.”

NEW BSL-4 ANNEX Also in 2018, crews began the site prep stage and pouring of the foundation for an annex

connecting to the Biosafety Level-4 (BSL-4) laboratory. BSL-4 is a high containment lab where scientists work on diseases for which there is no cure. This mechanical room expansion is about 2,600 square feet and will house new breathing air compressors and additional mechanical support equipment.

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The annex, to be completed in 2019, will allow Texas Biomed to maintain the current BSL-4 while construction continues on a Master Plan which includes a brand new level 4 high containment lab in the future.


GRANTS AND CONTRACTS

Awarded in 2018

COMMERICIAL GRANTS

PRINCIPAL INVESTIGATOR

SPONSOR AND TITLE

THEVAX CORPORATION HBV Vaccine Study in Baboons

Dr. Christopher Chen

UFOVAX LLC Development and Evaluation of HIV-1 UFO Trimer Presenting Nanoparticles

Dr. Robert Lanford

JANSSEN PHARMACEUTICALS, INC. Janssen Nonfederal: Analysis of 120 Non-Human Primate samples of study 20129586 in the Ebola Zaire

Dr. Luis Giavedoni

LENGTH

1 year

2 years

1 year

NEW AWARD TOTAL

SPONSOR AND TITLE

$291,238

$1,403,796

$68,161

Total from Commercial Research: $1,763,195 FEDERAL RESEARCH GRANTS

PRINCIPAL INVESTIGATOR

LENGTH

NATIONAL INSTITUTES OF HEALTH (NIH)/U OF N-LINCOLN Mucosal Delivery and Retention of Ebola Inhibitor Scytovirin Using Lactobacillus

Dr. Ricardo Carrion

1 year

$94,972

NIH — IL-10 as a host modifier of PZA activity

Dr. Joanne Turner

2 years

$239,375

SPONSOR AND TITLE

NEW AWARD TOTAL

NIH/WYOMING Womb to Tomb: Developmental Programming and Aging Interactions in Primates

Dr. Melanie Carless

5 years

$65,415

NIH/WYOMING Womb to Tomb: Developmental Programming and Aging Interactions in Primates

Dr. Robert Lanford

5 years

$3,813,940

NIH Epigenetics of energy homeostasis, bioenergetics and obesity

Dr. Melanie Carless

5 years

$3,378,488

NIH/IOWA Mechanisms and consequences of Plasmodium/Ebola virus co-infections

Dr. Olena Shtanko

2 years

$114,900

NIH Impact of Tat-binding Cellular LncRNAs on HIV replication

Dr. Smita Kulkarni

2 years

$526,625

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PRINCIPAL INVESTIGATOR

LENGTH

NEW AWARD TOTAL

NIH/U OF MD University of Maryland Animal Purchase – The Xenotransplantation Program

Dr. Karen Rice

1 year

$147,742

NIH/ SCRIPPS Uncleaved prefusion-optimized trimers on nanoparticles as HIV vaccines

Dr. Robert Lanford

5 year

$1,072,520

NIH Impact of Physical Activity on Striatal Reinnervation in a Nonhuman Primate Model of Parkinson’s Disease

Dr. Marcel Daadi

1 year

$710,357

NIH/U OF MD Rice University of Maryland Animal Purchase VS1582

Dr. Kare Rice

1 year

$95,276

NIH/CELDARA Treatment with CM-SV1 to Sudan virus infected NHP

Dr. Ricardo Carrion

2 years

$339,476

HARRY L. WILLET FOUNDATION/UTHSCSA A non-human primate model of Nontuberculous Mycobacterial (NTM) lung disease

Dr. Suzette Tardif

1 year

$15,266

SAN ANTONIO MEDICAL FOUNDATION Novel Biomarkers and Therapies in Kawasaki Disease

Dr. Jean Patterson

2 years

$130,000

DTRA/DAC Automated Approaches to Analyze and Identify Dual Use Research of Concern for Scientific Publications

Dr. Jean Patterson

1 year

$29,999

BARDA/MAPP BIO — Efficacy Studies for ZMapp CHO

Dr. Ricardo Carrion

2 years

$7,432,494

BARDA/BATTELLE Natural History of Rhesus Macaques Infected with Sudan Ebolavirus Disease

Dr. Ricardo Carrion

2 years

$1,489,964

FOOD & DRUG ADMINISTRATION Bordetella-Free Weanling Baboons

Dr. Karen Rice

1 year

$179,085

FOOD & DRUG ADMINISTRATION/NANOBIO Evaluation of mucosa; vaccination with Nano-Emulsion Adjuvant/Delivery system for Acellular vaccine

Dr. Karen Rice

2 years

$124,709


PRINCIPAL INVESTIGATOR

SPONSOR AND TITLE

LENGTH

NEW AWARD TOTAL

PRINCIPAL INVESTIGATOR

LENGTH

TEXAS MUTUAL Texas Mutual Insurance Company Safety Grant

Dr. Victor Pantusa

1 year

$1,500

SPONSOR AND TITLE

NEW AWARD TOTAL

FOOD & DRUG ADMINISTRATION Bordetella-Free Weanling Baboons

Dr. Karen Rice

1 year

$242,400

DEPARTMENT OF DEFENSE A Novel Strategy for Treating Peripheral Nerve Injury

Dr. Karen Rice

1 year

$234,626

BARDA/BATTELLE Efficacy study of mAb therapeutic against ZEBOV lethal challenge in rhesus macaques

TEXAS BIOMEDICAL FORUM Developing a novel diagnosis test for monitoring treatment success of drug resistant TB in low income areas

Dr. Jordi Torrelles

1 year

$60,000

Dr. Ricardo Carrion

2 years

$1,581,714

TEXAS BIOMEDICAL FORUM Lipid Mediators of Macrophage Metabolism and Immune Responses to Mycobacterium tuberculosis

Dr. Chrissy Leopold Wager

1 year

$59,985

$1,844,948

TEXAS BIOMEDICAL FORUM A novel strategy for Tuberculosis vaccine development

Dr. Varun Dwivedi

1 year

$59,959

TEXAS BIOMEDICAL FORUM Engineering pathogen triggered biomeneralization to enable a new generation of sample-to-answer tests

Dr. Andrew Hayhurst

1 year

$60,000

DOUGLASS FOUNDATION Douglass Foundation Fellowship

Dr. Tucker Piergallini

1 year

$40,800

KRONKOSKY CHARITABLE FOUNDATION BSL3 Equipment Package Donation

Dr. Larry Schlesinger

2 years

$750,000

DOUGLASS FOUNDATION Douglass Foundation Fellowship

Dr. Colwyn Headley

1 year

$41,790

KUMAMOTO UNIVERSITY Development of antiretroviral agents that penetrate the central nervous system and exert potent activity against various HIV-1 v2

Dr. Ruth Ruprecht

1 year

$17,752

UNIVERSITY OF TEXAS HEALTH - SAN ANTONIO External Sale for Hyperglycemia Increases Peripheral Insulin Insensitivity and Alters Pancreatic Development in Baboons

Dr. Karen Rice

1 year

$20,883

BARDA/REGENERON Efficacy study of mAb therapeutic against EBOV lethal challenge in rhesus macaques

2 years

Dr. Ricardo Carrion

Total from Federal Research: $23,904,291 PHILANTHROPIC AND PRIVATE RESEARCH GRANTS SPONSOR AND TITLE

PRINCIPAL INVESTIGATOR

LENGTH

NEW AWARD TOTAL

WILLIAM & ELLA OWENS MEDICAL RESEARCH FOUNDATION Epigenetic editing of neuronal cells as a treatment modality in Alzheimer’s disease

Dr. Melanie Carless

COWLES MEMORIAL TRUST Lipid Mediators of Macrophage Metabolism and Immune Responses to Mycobacterium tuberculosis

Dr. Chrissy Leopold Wager

1 year

$65,766

BILL & MELINDA GATES FOUNDATION/ORHSU Non Surgical Methods of Permanent Contraception

Dr. Karen Rice

1 year

$83,809

1 year

$68,818

Behalf of Genomics

1 year

$28,445

Dr. Suzette Tardif

2 years

$139,022

FOUNDER’S COUNCIL Equipment: Storz Endoscopy Unit

Pat Frost, Veterinary

FOUNDER’S COUNCIL Pippin HT DNA Size Selection System

Shelley Cole, on

PERRY AND RUBY STEVENS CHARITABLE FOUNDATION/UTSA Translantation of Induced Pluripotent stem cell (iPSC) derived dopaminergic neurons to restore function in MPTP treated baboons

Research Resources

2 years

$190,634

Total from Philanthropic and Private Research: $1,689,163 TOTAL OF NEW GRANTS AND CONTRACTS: $27,356,649

21


Texas Biomed Contributions

GIVING IS INFECTIOUS TOO!

P

ainting a scary scenario in his new book The Pandemic Century: One Hundred Years of Panic, Hysteria, and Hubris, author Mark Honigsbaum recaps the emergence of nine infectious diseases including Ebola, HIV, Zika and influenza. These are huge health threats and biomedical mysteries. The book paints an uncertain view of the future. However, what he didn’t account for are researchers like those at Texas Biomedical Research Institute – some of the best scientific minds in the country – mounting a battle to win the war against these pathogens. What do infections have to do with giving? I believe giving is infectious. One of my early mentors called the magic that happens when a contributor “gets it” as catching the “donor bug.” Positively, this “bug” moves from one participant to the next and can accumulate miraculous resources… technologies, facilities and experts at places like Texas Biomed.

Our founder, Tom Slick, Jr., knew about the power of philanthropy and its ability to be contagious. Giving created Texas Biomed. Giving has built our campus. Giving sustains us today. Giving is part of our history and our future. Now is the time to catch the “bug” as Texas Biomed implements a bold, 10-year plan to grow our resources to match the pathogenic challenges of the future and enemies like tuberculosis, MRSA, and pneumonia, to name just a few. Meeting the challenges of the future requires the contributions of each of us today. The generosity of our supporters powers our progress. Join the scientific revolution today. It’s infectious!

Corbett Christie

FOR MORE INFORMATION ABOUT GIVING OPPORTUNITIES, PLEASE CONTACT TEXAS BIOMED VICE PRESIDENT FOR ADVANCEMENT AND PUBLIC RELATIONS CORBETT CHRISTIE AT (210) 258-9870 OR CCHRISTIE@TXBIOMED.ORG, OR VISIT OUR WEBSITE AT WWW.TXBIOMED.ORG AND CLICK ON SUPPORT US.

22


CIRCLES OF GIVING CHAIRMAN’S CIRCLE

Mr. and Mrs. Jack E. Guenther, Jr.

Mr. Lanham Napier and Dr. Dacia Napier

PRESIDENT’S CIRCLE

Mr. and Mrs. Rex Mitchell Amini

Mr. and Mrs. Curtis C. Gunn, Jr.

Dr. Peter W. Nathanielsz

2011 Eric Hill Gift Trust

Dr. and Mrs. C. Collins Anderson

Mr. and Mrs. Frederic Hamilton

Nelson Puett Foundation

Advantage Pain Management

Mr. and Mrs. Robert A. Anderson

Mr. and Mrs. Michael Harper

Mr. and Mrs. John E. Newman, Jr.

Alamo Group

Mrs. Robert R. Archer

H-E-B

Mr. and Mrs. Thomas I. O’Connor III

Mr. and Mrs. John C. Asel

Mr. and Mrs. Edward H. Austin, Jr.

Helen Groves Fund

Mr. and Mrs. Alex H. Oliver

Mr. and Mrs. Brian and Emmy Ballantyne

Mr. and Mrs. Richard N. Azar II

Mr. and Mrs. Ronald J. Herrmann

Mr. Williams Owens

Mr. and Mrs. Edgar A. Basse III

Mr. and Mrs. Sam P. Bell, Jr.

Mrs. George C. Hixon

Phoenix Charitable Foundation

Mr. and Mrs. Craig Boyan

Betty Stieren Kelso Foundation

Mr. and Mrs. George “Timo” Hixon

Mr. and Mrs. Andrew Price

Dr. and Mrs. Ronald K. Calgaard

Bill and Melinda Gates Foundation

Tim and Karen Hixon Foundation

Mr. and Mrs. Nelson H. Puett

Cappy’s

Mr. and Mrs. Craig Boyan

Hixon Properties, Inc.

Mrs. Judy Renick

Mr. Chris Cheever

The Brown Foundation, Inc.

Mr. and Mrs. John R. Hurd

Mr. and Mrs. Barry Coates Roberts

Dr. Robert R. Clemons

Mr. Charles C. Butt

John and Florence Newman Foundation Mr. and Mrs. William A. Johnson

Roger L. and Laura D. Zeller Charitable Foundation

Mr. and Mrs. Justin Cole

Mr. and Mrs. Robert Cavender Mr. and Mrs. Charles E. Cheever, Jr.

Mr. and Mrs. George A. Kampmann, Jr.

Dr. and Mrs. James M.O. Rubin

Mr. and Mrs. John W. Feik

Ms. Phyllis Slick Cowell

Mr. and Mrs. Richard Kardys

The Ruth and Edward Austin Foundation

Mr. H. Rugeley Ferguson, Jr.

Mr. and Mrs. Trey Dawson

Mr. Robert E. Kelso

Mr. and Mrs. Ron Finch

Mr. and Mrs. James L. Donnell, Jr.

Mr. and Mrs. John C. Kerr

Ruth Chapman Cowles & Andrew G. Cowles Memorial Fund

Mrs. James L. Donnell

Mr. and Mrs. William R. Klesse

RWM Foundation

Mr. and Mrs. Thomas Albert Gates, Jr.

Douglass Foundation

Klesse Foundation

San Antonio Area Foundation

Mr. and Mrs. Stephen Goebel

Mr. and Mrs. Alan W. Dreeben

Mr. and Mrs. Cappy Lawton

Mrs. Marie Halff

Elizabeth Huth Coates Charitable Foundation

Ms. Kimberly Spicer Lewis

Mr. Richard T. Schlosberg and Dr. Kathy Schlosberg

Mr. Donald G. Elliott

Mr. Rodney Ray Lewis

Mr. and Mrs. Thomas R. Semmes

Mr. and Mrs. Joe N. Haynes

Mr. and Mrs. Walter Embrey Jr.

Mr. James R. Marmion III

The Honorable and Mrs. John Shields

Ms. Jane Ballantyne Hegeler

Mr. and Mrs. John Feik

Ms. Mary Sue Marmion

Mr. Charles Urschel Slick

Mr. and Mrs. John L. Hendry III

Fletcher Jones Foundation

Mr. and Mrs. L. Lowry Mays

Mrs. Louis Stumberg

Mr. and Mrs. Roger C. Hill, Jr.

Founder’s Council

Mr. and Mrs. Mark P. Mays

Texas Biomedical Forum

Mr. and Mrs. Timo Hixon

G. Harold and Leila Y. Mathers Charitable Foundation

Mays Family Foundation

Mr. and Mrs. Jon Turner

Mr. Thomas Francis Hogan III

Mr. and Mrs. Alex McAlister

Mr. and Mrs. Curtis T. Vaughan III

Mr. and Mrs. Andrew Hunt

Mr. and Mrs. Joseph W. Gorder

Mr. and Mrs. B.J. McCombs

V.H. McNutt Memorial Foundation

Mr. Walter Juliff

Gorman Foundation

McCombs Foundation

Virginia C. Joslin Trust

Mr. and Mrs. Joseph B. Labatt

Mr. and Mrs. James W. Gorman, Jr.

McCrea Foundation

Wave Healthcare, LLC

La Fonda on Main

Mr. and Mrs. William E. Greehey

Mrs. Lewis J. Moorman III

Mr. and Mrs. Edward C. Welsh

Mr. and Mrs. Steven Q. Lee

Mrs. Helen Kleberg Groves

Mr. and Mrs. Lewis J. Moorman IV

Mr. Richard F. Lord (In Memoriam)

Jack and Valerie Guenther Foundation

Ms. Judith N. Morton

William and Ella Owens Medical Research Foundation

Mr. and Mrs. Jack Guenther

Ms. Patricia P. Muir

The Honorable and Mrs. W. Reed Williams

23

Mr. and Mrs. Peter B. Dahlberg

Mr. William Ford

Harris K. & Lois G. Oppenheimer Foundation

Lorene March Partnership CONTINUED ON PAGE 24


CONTINUED FROM PAGE 23

Mr. and Mrs. John Brozovich

Mr. and Mrs. Joe C. McKinney

GOLDEN CIRCLE

Mr. Michael Joseph Lynd, Jr.

Mr. and Mrs. J. Byron Burton III

Mr. and Mrs. Sean McNelis

Mr. and Mrs. Guy Wade Caldwell

Mr. Barclay C. Adams

Mr. and Mrs. Clark R. Mandigo II

McNelis + Associates

Mr. and Mrs. Richard W. Calvert

The Honorable and Mrs. Clyde H. Alexander

Mr. and Mrs. David Mauze

Mrs. Paul E. McSween, Jr.

Mr. and Mrs. Claiborne Ayres Carrington

Mr. and Mrs. Brett Alvheim

Mauze Construction

Mr. and Mrs. John K. Meyer

Ms. Jean Cheever

Mr. and Mrs. Michael Richard Amini

Mr. and Mrs. Matthew Z. Mosser

Mr. and Mrs. Scott Fraser Anderson

MW Construction

Dr. Sarah Trampota Conquest and Mr. Andrew Conquest

Minnie Stevens Piper Foundation Mr. and Mrs. William G. Moll

Mr. and Mrs. Brian Arriaga

Mr. and Mrs. Sergio Montemayor

Ms. Ann Griffith Ash

Mr. and Mrs. James R. W. Daniell

Pape-Dawson Engineers, Inc.

Mrs. Isabelle Badouh

Mr. and Mrs. Christopher H. Dewar

Mr. and Mrs. Gardner Peavy

Mr. and Mrs. Jeff P. Bailey

DuWest Realty

Mr. and Mrs. Scott Petty, Jr.

Mr. and Mrs. William J. Baine

Mr. Thomas H. Edson

Project Control of Texas

Mr. and Mrs. James D. Ellis

R.L. Worth Family, L.P.

Ferguson Enterprises, Inc.

RSM US LLP

Mr. Robert H. Finney and Dr. Nancy A. Finney

Dr. and Mrs. Frank C. Sammis III

Mrs. Charles E. Foster

Mr. and Mrs. William Scanlan, Jr.

Mr. and Mrs. Aubra L. Franklin

Silver Eagle Distributors

Ms. Lynn Tidwell Neff Nordan Trust Mr. Charles G. Northrup Mrs. Claire Oppenheimer O’Malley Mr. and Mrs. George Parker, Jr. Mr. and Mrs. Allan G. Paterson Ms. Roxana McCallister Richardson Rugeley Ferguson Foundation Mr. and Mrs. James B. Smith Mr. and Mrs. Jack J. Spector Mr. and Mrs. S. Van Stewart Dr. Joanne Turner Uhl, Fitzsimons, Kewett & Burton, PLLC Ms. Ann Brennand Watson Mr. and Mrs. Warren S. Wilkinson, Jr. Mr. and Mrs. James P. Zachry Mr. and Mrs. John B. Zachry

BENEFACTOR’S CIRCLE Mr. and Mrs. Aaron Asel

Daniel J. Sullivan Family Charitable Foundation

Frost Bank

Mr. and Mrs. Bruce A. Smith

Mr. and Mrs. James L. Glover

Mr. and Mrs. Joseph Stewart Bakke Mr. and Mrs. Stephen P. Ballantyne Mr. and Mrs. A.L. Ballard Mr. and Mrs. James Hunter Barrow Mr. Bruce B. Barshop Mrs. Sam Barshop Mr. and Mrs. Lee M. Bass Mr. and Mrs. J. Dan Bates

Mr. and Mrs. James B. Smith, Jr.

Mr. and Mrs. Jim Baxter

SpawGlass

BB&T

Dr. and Mrs. Norton A. Stuart III

Mr. and Mrs. Brian Beem

Mrs. Daniel J. Sullivan IV (In Memoriam)

Mr. and Mrs. Will Alston Beinhorn

The Tobin Endowment

Mr. and Mrs. Jonathon Beitz

Mr. and Mrs. John R. Hurd, Jr.

TransPecos Banks

Mr. and Mrs. Michael D. Beldon

Jackson Walker, LLP

Mrs. Marion Dewar Bell

Joeris General Contractors

Mr. Dale W. Tremblay and Dr. Sandra Tremblay

Mr. and Mrs. Michael L. Benedum

Mr. and Mrs. James B. Griffin Guido Construction Mr. and Mrs. Harry Halff Mr. and Mrs. Reagan Houston IV Mr. and Mrs. Mark S. Howard

Mr. and Mrs. Matthew M. Bell

Joseph and Madelon Harrison Family Advised Fund

Mr. and Mrs. Jason Westmoreland

Asel and Associates

Dr. and Mrs. Gary Koehl

Mr. and Mrs. Edward E. Whitacre, Jr.

Mr. and Mrs. Barry G. Benton

Mr. and Mrs. Geary Atherton

Mr. and Mrs. Bob Kolitz

Mr. and Mrs. Jack Williams III

Mr. and Mrs. Ryan Berg

Bank of America

Lt. Gen. Frank (In Memoriam) and Mrs. Marilyn Ledford

Mr. and Mrs. James M. Wolff

Mr. and Mrs. Richard Bergmann

Bank of San Antonio

Mr. and Mrs. Clint Worth

Mr. Jeffrey H. Berler

Mr. and Mrs. Brian Beem

Mr. Samuel E. Maclin

Ms. Margery L. Block

Mr. and Mrs. Robert L. Worth, Jr.

Ms. Ann Marmion

Broadway Bank

Marsh Wortham

Mrs. Walter F. Brown

Matera Paper Company

Brown and Ortiz, P.C.

Mr. and Mrs. Robert S. McClane

Advantage Pain Management

Worth and Associates Mr. and Mrs. Keith Zars

Mrs. Lawrence A. Bertetti Mr. and Mrs. Albert M. Biedenharn III Mr. and Mrs. Tim Blonkvist Mr. and Mrs. Cooper N. Boddy Mr. and Mrs. Greg Bolner

24


Congressman and Mrs. Henry Bonilla

Mr. and Mrs. Jeffrey de Rojas

Mr. and Mrs. Robert Gurwitz

JP Morgan

Mr. and Mrs. Robert L. Bowers

Mr. and Mrs. Michael Dewar

Mr. and Mrs. Ricardo Guzman

Mrs. George A. Kampmann

Miss Marrs McLean Bowman

Mr. and Mrs. Robert L. Dewar

Mr. and Mrs. Mark Hanrahan

Mr. and Mrs. Patrick J. Kennedy

Mr. and Mrs. McLean Bowman

Mr. and Mrs. Kenneth Dorbandt

Mr. and Mrs. William E. Harrison, Jr.

Mr. and Mrs. Patrick J. Kennedy, Jr.

Mr. Paul Bracher

Mr. and Mrs. Taylor Dorris

Ms. Mary Austin Hart

Mr. and Mrs. Evan Ketabchi

Mr. Jonathan Bradley

Mr. and Mrs. William E. Dreyer

Mr. and Mrs. Warren B. Hart II

Mrs. Sue Killam

Dr. and Mrs. Warren B. Branch

Mr. and Mrs. Donald Y. Duffin

Mr. and Mrs. Houston Harte

Mr. and Mrs. Creston A. King III

Mr. and Mrs. James C. Browning

Mrs. Betty Ann Ebrom

Mr. H. Burt Hause

Mr. and Mrs. Robert A. Kiolbassa

Mr. and Mrs. Harry H. Brusenhan

Mr. and Mrs. Jeff Edwards

Mr. and Mrs. Albert F. Hausser

Kittie Nelson Ferguson Foundation

Mr. and Mrs. James H. Bryan, Jr.

Mr. and Mrs. Michael Ellis

Mr. and Mrs. James L. Hayne

Mr. Shaj and Dr. Avina Kolareth

Mr. and Mrs. J. Bruce Bugg, Jr.

Eugenia and Lawrence A. Bertetti Foundation

Mrs. Frances J. Hearn

Mr. Bart Koontz

Mrs. George V. Burkholder

Dr. and Mrs. John A. Evans

Mr. and Mrs. Jeffrey E. Heinke

Mr. and Mrs. Edward K. Kopplow

Mr. and Mrs. Stephen W. Butt

Mr. and Mrs. Richard W. Evans, Jr.

Mr. and Mrs. Roger Hemminghaus

Mr. and Mrs. John C. Korbell

Mrs. Walter J. Buzzini III

Mr. and Mrs. John Feik, Jr.

Mr. and Mrs. Stuart Carl Hendry

Mr. and Mrs. Gregory W. Kowalski

Mr. and Mrs. A.H. Cadwallader IV

Mr. Robert H. Finney and Dr. Nancy A. Finney

Mr. Jonathan Hess

Ms. Rosemary Kowalski

Mr. and Mrs. Presnall Cage

Mr. and Mrs. Eric Fisher

Ms. Henrietta P.C. Hildebrand

Mr. Michael L. Kreager

Dean Charles E. Cantu

Mr. and Mrs. Hugh Fitzsimons, Jr.

Mr. and Mrs. Russell Hoermann

Dr. and Mrs. Ariel Kruger

Dr. and Mrs. Carlos Cardenas

Mr. and Mrs. W.W. Flannery, Jr.

Mr. and Mrs. Benjamin B. Holliday

Mr. and Mrs. William Jeffrey Kuhn

Dr. Melanie Carless and Dr. Mark Kos

Mr. Charles A. Forster

Mr. and Mrs. Charles R. Hollimon

Dr. and Mrs. Robert Lanford

Mr. and Mrs. John Brozovich Cardno

Mr. and Mrs. Tom Frost, Jr.

Dr. Peter W. Hollimon and Dr. Mary H. Arno

Mr. and Mrs. Clint Lawson

Mrs. Cassandra C. Carr

Mr. and Mrs. Mark Garcia

Mr. and Mrs. Al Honigblum

Mr. Trevor Lawton and Ms. Amy Stinson

Mr. and Mrs. William Carrington

Mr. and Mrs. David Gard

Mr. and Mrs. Michael Howard

Mr. and Mrs. Milton B. Lee

Mr. and Mrs. James M. Caruth

Mr. and Mrs. George A. Geis

Mr. and Mrs. Ladd J. Howell

Mr. and Mrs. Byron L. LeFlore, Jr.

Mrs. James M. Cavender III

Mr. and Mrs. Evan Gerald

Mr. and Mrs. Dan Allen Hughes, Jr.

Mr. and Mrs. Ralph Lehr, Jr.

Mr. and Mrs. Pedro Cerisola

Mr. Lukin T. Gilliland, Jr.

Mr. Christian Hummel

Mr. and Mrs. Thomas Robert Leslie IV

Mr. and Mrs. B. Corbett Christie

Dr. and Mrs. Joseph W. Goldzieher

Mr. and Mrs. Andrew Hunt

Mrs. John R. Less

Mrs. Malcolm H. Cohen

Dr. and Mrs. William Gordon

Ms. Sara Smith Hurd

Mr. and Mrs. Steve C. Lewis

Mrs. Richard T. Coiner III

Mr. and Mrs. Chase Gorman

Jackson Walker, LLP

Mr. and Mrs. Cinco Light

Mr. and Mrs. Norborne P. Cole, Jr.

Mr. and Mrs. James B. Gouger

Mr. and Mrs. Kenneth M. Jastrow II

Ms. Joyce Lindler

Mrs. George J. Condos

Mr. and Mrs. John Paul Gould

Mr. and Mrs. Jeremy Jessop

Ms. Judith Lindquist

Mrs. John Crichton

Dr. and Mrs. Joseph Grant

Mr. and Mrs. Taylor Little

Mr. Michael Cruz and Mrs. Lisa Cruz

Mr. and Mrs. Claiborne B. Gregory, Jr.

Jody and Sheila Grant Fund of Communities Foundation

Mr. and Mrs. Paul T. Curl

Mr. and Mrs. James B. Griffin

Mr. and Mrs. Henry Clay Johnson

Mr. and Mrs. Cullen Rogers Looney

Mr. and Mrs. James R.W. Daniell

Mr. and Mrs. Brandon E. Grossman

Dr. Johnny Clay Johnson

Mr. and Mrs. Porter Loring, III

Mr. Keith A. Davis

Mr. and Mrs. Craig J. Guaransuay

Mr. and Mrs. Tony C. Johnson

Mr. and Mrs. Howard H. Lutz

Mr. Taylor Dawson

Dr. and Mrs. Kennon Guglielmo

Mr. and Mrs. Ansley E. Johnston

Mr. and Mrs. Mike MacNaughton

Mr. and Mrs. Jeffrey de Rojas

Mr. and Mrs. Cosmo M. Guido

Mr. and Mrs. J. Bradley Jones

Mrs. Leroy G. Denman, Jr.

Mr. and Mrs. Thomas L. Guido

Mrs. Joe Warren Jones

Mr. and Mrs. Glenn MacTaggart CONTINUED ON PAGE 26

25

Mr. and Mrs. David G. Lloyd, Jr.


CONTINUED FROM PAGE 25

Ms. Evangeline Myers

Mr. and Mrs. David Schlagel

Mr. Kenneth Edward Train

Mr. and Mrs. Gregory Mann

Mr. and Mrs. Robert L. Myers

Dr. and Mrs. Larry S. Schlesinger

Mr. and Mrs. Richard C. Traylor

Mr. and Mrs. Bob Marbut

Mr. and Mrs. Scott Nathan

Mr. and Mrs. J. Thomas Schmidt

Mr. Kenneth P. Trevett

Ms. Margo Spitz Marbut

Mr. and Mrs. John Liston Nau III

Mrs. Robert L. Schupbach

Dr. and Mrs. George J. Vassar

Mr. and Mrs. Madison C. Marceau

Mr. and Mrs. Eric Neuner P.E.

Mr. and Mrs. Harry F. Schwethelm, Jr.

Mr. and Mrs. Chris Marco

Mr. and Mrs. David F. Nicolson III

Mr. and Mrs. Stuart Seal

Marsh Wortham

Dr. and Mrs. Aris Nikas

Mrs. H. Kyle Seale

Mr. and Mrs. Charles G. Martens

Mr. and Mrs. John A. Oberman

Mr. and Mrs. Donnie Seay

Mr. and Mrs. Keith O’Connell

Mr. and Mrs. Peter C. Selig

Mr. and Mrs. Lawrence O’Connor

Dr. and Mrs. Antonio Serna, IV

Mr. and Mrs. W. Lawrence Walker III

Mr. Robert Ochoa

Mr. and Mrs. Robert Eric Shaw

Mr. and Mrs. Neill Bailey Walsdorf

Mr. and Mrs. Steven M. Ogle

Mr. and Mrs. Chip Shirley

Mr. and Mrs. Mark E. Watson, Jr.

Mrs. Clara Shovlin

Mr. and Mrs. Mark E. Watson III

Mr. and Mrs. Pete Sitterle

Mr. and Mrs. Conrad Weaver

Mr. Charles U. Slick, Jr.

Mrs. Don E. Weber

Mr. Tom B. Slick, Jr.

Mr. and Mrs. Dan G. Webster III

Mr. Paul Martin Mr. and Mrs. Madison Mauze Mr. and Mrs. Jess Mayfield Mr. and Mrs. Chance Mazurek Mr. and Mrs. Alexander S. McAllister Mr. and Mrs. Walter W. McAllister III Mr. and Mrs. David McArthur Mr. David and Mrs. Jeannie Hegeler McArthur Mr. and Mrs. Norris Robert McClane Mr. and Mrs. Don B. McDonald, Jr. Ms. K. Heather McFarlin Mr. and Mrs. Elkin McGaughy Mrs. Anne O. McNeel Mrs. Jo Lynne Meador Dr. and Mrs. Gilbert R. Meadows

Mrs. Frederic J. Oppenheimer Mrs. Susan Oppenheimer Mr. and Mrs. William B. Osborn III Mr. and Mrs. John Carroll Park

Dr. and Mrs. Lon S. Smith

Mrs. Harry J. Parker

Mr. and Mrs. J. Dudley Snyder

Mrs. William A. Parker

Mrs. Marshall T. Steves, Sr.

Dr. and Mrs. Mahendra Patel

Mr. and Mrs. Sam Bell Steves III

Mr. and Mrs. Henry B. Paup

Mr. and Mrs. Drew Stewart

Mrs. Tom E. Pawel

Mrs. John Stewart

Dr. and Mrs. Daniel C. Peavy Mr. and Mrs. Gardner Peavy Mr. and Mrs. Christopher Petty

Mr. and Mrs. Ben F. Vaughan IV Mr. and Mrs. Michael N. Venson Mr. and Mrs. Jack Vexler Mr. and Mrs. W. Lawrence Walker, Jr.

Mr. and Mrs. Alex P. Weekes Mr. and Mrs. Heath Wenrich Ms. Kittie West Whataburger Dr. Alexis Wiesenthal

Mr. and Mrs. Julian C. Stewart

Ms. Francie Whittenburg

Mr. and Mrs. Leland M. Stone

Mr. and Mrs. Chris Wilde

Mr. and Mrs. Matthew Strange

Mr. and Mrs. James Y. Williams

Mrs. Thomas D. Stribling

Mr. and Mrs. Roger Winter

Mr. and Mrs. L. Herbert Stumberg, Jr.

Mr. and Mrs. George J. Wommack

Mr. Eduardo Meza

Mr. and Mrs. John A. Peveto, Jr.

Mr. Fred W. Middleton

Mr. and Mrs. Philip J. Pfeiffer

Milam Real Estate

Mr. and Mrs. Alistair F. Philip

Mr. and Mrs. Balous T. Miller

Mr. and Mrs. William “Dub” Sutherland

Mr. Ben Pressentin

Mr. and Mrs. John G. Wright

Mr. and Mrs. Joe Miller

Mr. and Mrs. William Sutherland

Mr. and Mrs. William H. Quirk IV

Mrs. Leon C. Wulfe, Jr.

Dr. and Mrs. Joseph P. Miller

Mr. and Mrs. Timothy L. Swan

Mr. and Mrs. Lane Riggs

Mission Title

Mr. and Mrs. Stephen Lee Swanson

Dr. and Mrs. Mark C. Rittenhouse

Mr. Patrick H. Swearingen, Jr.

Mr. and Mrs. Stuart D. Moiles

Mr. and Mrs. Paul Rohlfs

Dr. and Mrs. Casey Taber

Mr. and Mrs. Michael L. Molak

Mr. and Mrs. Paul A. Rohlfs, Jr.

Mr. Charles W. Tate

Mr. and Mrs. Edward D. Moore

Mr. and Mrs. Forrest Runnels, Jr.

Dr. and Mrs. Alvin Thaggard III

Mr. and Mrs. Keith Zars

Mr. and Mrs. John Moorman

Mrs. Ruth Bowman Russell

Mr. and Mrs. John C. Thomas

Mr. and Mrs. Joshua Zeller

Mrs. Jeffrey M. Morehouse

RVK Architects

Mr. Ron Thompson

Mr. and Mrs. Thad W. Ziegler

Mr. and Mrs. Randall Morris

Dr. and Mrs. Frank C. Sammis III

Dr. and Mrs. Brad S. Tolin

Mrs. Marion C. Zoch

26

Mr. Mike Yantis Yantis Company Mr. and Mrs. Peter Zacher Mr. and Mrs. H. Bartell Zachry, Jr.


TEXAS BIOMED FORUM

I

n 1970, Dottie Block, Tena Gorman and Ruth Eilene Sullivan had a vision to create an organization of dedicated and like-minded women to support Texas Biomed. The cornerstone of this organization was built on ideals implemented by our founders: volunteerism, community relations and fundraising — standards of success that the Forum upholds enthusiastically today. Our unofficial mantra this year has been, “Women Supporting Science and Each Other” and what a year we have had!

THE WORK OF THE FORUM IS VITAL TO FUND THOSE IDEAS IN THE INCUBATOR STAGE SO THAT TEXAS BIOMED SCIENTISTS CAN CONTINUE DOWN THE PATH OF SCIENTIFIC DISCOVERY.

Community relations took on many dynamics this year, with our Lecture Luncheons, Cocktails with Scientists Roundtable, Cheers to Chairity, and our student outreach efforts via our student tours program and Science Education Awards. We began this year with our Fall Lecture Luncheon, a hallmark of our outreach efforts. Dr. Joanne Turner, Texas Biomedical Research Institute’s Vice President for Research and a previous Forum Grant recipient, discussed her career, professional goals and the role of women in science and executive leadership positions. This was followed by our Cocktails with Scientists Roundtable program which allowed our members and guests to interact with multiple scientists in one evening. In the fall, we hosted our Past Presidents at a luncheon generously sponsored by Texas Biomed at The Argyle. We honored the legacy of the outstanding women who have guided this organization for more than 40 years and celebrated the strong future that lies ahead for the Forum. We are incredibly grateful for the ongoing support from our esteemed group of Past Presidents. They have and continue to shape our organization in many ways.

Over the course of the Forum’s storied history, the organization has raised over $3 million for Texas Biomed pilot studies via our Forum Grants program. These seed grants, the Forum’s initial investment in promising work, has returned $83 million in additional funding for Texas Biomed. We often say that what starts at the Forum plants the seed to change the world. It is one of the most rewarding aspects of serving the Forum, to see Texas Biomed scientists achieve great success after receiving one of our grants.

In February, the Forum hosted our second Cheers to Chairity event in which 12 talented local designers reimagined dining chairs generously donated by The Argyle after the recent renovation projects. This beautiful event was another successful Forum fundraiser. We welcomed spring with our second lecture luncheon of the year where Texas Biomed President and CEO, Larry Schlesinger, M.D. discussed, “You, Your Loved Ones and Infection: The Impact of Infection on Our Daily Lives.” At this event, we also recognized the winners of our 25th annual Science Education Awards. This beloved program was founded by former Forum Trustee Valerie Guenther and former Forum President Jerilyn Blanchard. Our ongoing partnership with Mrs. Guenther and the V.H. McNutt Memorial Foundation allows the Forum to recognize outstanding local high school science teachers who are developing innovative, hands-on science curriculum. This year’s winners presented outstanding projects that spanned several science genres and

Thanks to our Board of Trustees, Advisors, Honorary Advisors, and general membership, we are able to impact the work of Texas Biomed in a variety of ways. Forum membership dues help fund our general needs such as operating expenses, administrative costs and most importantly, our Science Education Awards Program for teachers. Membership in the Forum is open to all women 21 years of age and over interested in promoting the work of the Forum and Texas Biomed. Our membership campaign kicks offs every summer and membership can be initiated or renewed online at any time.

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represented Saint Mary’s Hall, Cornerstone Christian School and Earl Warren High School.

(l to r) Denise Mosser, Chair of the 2018 Gala, presented a check for the 2018 Gala proceeds to Dr. Larry Schlesinger, Texas Biomed President/ CEO alongside Nicole McClane, Gala Co-chair and Courtney Percy, 2017-2018 President of the Forum.

Throughout the year, Forum Trustees also serve as ambassadors for local high school science classes touring the Texas Biomed campus. This year’s participants included students from Saint Mary’s Hall, Southside High School, Lee High School’s STEM program, La Vernia High School and Natalia High School. The hallmark of the Forum year is always our annual Gala, held the first Saturday of May. One of the most highly anticipated social events of the year, each Gala is thematically unique and crafted with great care by our outstanding Gala team. This talented group of volunteers executed another phenomenally successful event with, “The Night They Invented Champagne.” Funds raised at The Gala and as part of our Forum Grants efforts are utilized to fund pilot studies by Texas Biomed scientists to achieve results needed to apply for larger grants funded by national and government agencies.

The Forum awarded $251,294 in grants to scientists at Texas Biomedical Research Institute

to assist in developing preliminary data that will enable these scientists to secure future funding for novel projects. The following projects were funded in 2018.

SCIENTISTS Andrew Hayhurst, Ph.D. Dr. Hayhurst’s project is a proof-of-concept study to evaluate the potential of a novel process for the facile detection of pathogens in the field. Using Marburg virus as our model pathogen, his team will test the feasibility and sensitivity of the system.

You may have noticed our newsletters while visiting The Argyle. These are printed three times a year and are mailed to members and made available digitally on our website. The Forum is also active on social media, including Facebook, Instagram and LinkedIn. These combined efforts allow the Forum to share important information about the groundbreaking work at Texas Biomed with our membership as well as an audience of potential supporters and enthusiastic volunteers.

Jordi Torrelles, Ph.D. Dr. Torrelles is working to develop and test the performance of a 2nd generation TB Color Plate test with the ultimate goal of developing and implementing a faster (14 vs. 56-84 days), fieldbased, easy-to-use and inexpensive drug susceptibility testing (DST) for drug-resistant TB in high TB index rate regions. This will allow faster detection, cost reductions, and thus, significantly aid in preventing transmission of drug-resistant TB in humans.

The Forum greatly values what a treasure Texas Biomed is, and we are honored to work to educate the community about the importance of the scientific work being accomplished on campus. There is so much truth in the statement that what starts at the Forum plants the seed to change the world. The work of the Forum is vital to fund those ideas in the incubator stage so that Texas Biomed scientists can continue down the path of scientific discovery.

STAFF SCIENTISTS

Thanks to our past leadership, the Forum continues to be an organization of distinction. Personally, I am grateful to all those who have invested their time and resources in this outstanding organization. It has been both a tremendous honor and a great privilege to serve as this year’s Forum President. I look forward to cheering the Forum on as the organization continues to grow and accomplish great things. With gratitude and in service,

Jody Lutz, 2018 Forum President

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Varun Dwivedi, Ph.D. Dr. Dwivedi proposes a strategy of host derived IL-10 modulation, strictly at the time of vaccination for generating a qualitatively different set of T cells resulting in sustained long-term protection against M.tb infection in mice.

POST-DOCTORAL SCIENTISTS Chrissy Leopold Wager, Ph.D. Macrophages are host immune cells that are critical for controlling TB. Dr. Leopold-Wager’s project focuses on the role of lipid signaling molecules known as eicosanoids on macrophage responses. We are investigating the kinetic release of eicosanoids in TB infected human macrophages and will determine the effects of eicosanoids on macrophage activation and metabolism as well as TB pathogenesis. This project will provide insight into pathways that can be targeted for novel approaches to host-directed therapy for TB.


FOUNDER’S COUNCIL

T

he Founder’s Council is a dynamic group of professionals and young leaders between the ages of 25 and 46 founded in 1988 to honor the memory of Tom Slick and to promote Texas Biomedical Research Institute.

THE FOUNDER’S COUNCIL EXISTS TO EDUCATE ITS MEMBERS ABOUT THE LIFE-CHANGING RESEARCH CONDUCTED EVERY DAY AT TEXAS BIOMED.

Historically, the Founder’s Council has distributed 10 to 15 equipment grants per year ranging from $2,500 to $7,500 each. In 2018, the Founder’s Council board of directors voted in favor of distributing fewer yet higher-value grants. We are very proud to report that our grants — which now average $40,000 each — are even more impactful to Texas Biomed.

The mission of the Founder’s Council is to cultivate interest in Texas Biomed among young leaders in the greater San Antonio region who show potential for lifelong support of Texas Biomed. The Founder’s Council has approximately 400 diverse members from all walks of life whose annual contributions and sponsorships help fund equipment grants for Texas Biomed scientists. Texas Biomed had an exciting 2018 as Dr. Larry Schlesinger settled into his new position as President and CEO.

As President of the Founder’s Council, I was honored to be an ex officio member of the Texas Biomed Board of Trustees. In Board meetings, I had a unique opportunity to witness the leadership, vision, and confidence that Larry brings to Texas Biomed. In June 2018, he received Board approval to undertake an aggressive strategic plan to completely rebuild the Texas Biomed campus, increase staff and funding, and most importantly, help Texas Biomed become known throughout the world. Larry has earned the respect of his staff, our board of directors and City leaders. I would like to thank him personally for his guidance and support throughout the year. Because we know that behind every successful man is a supportive woman, I also would like to thank the First Lady of Texas Biomed, Larry’s wife, Judy.

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The Founder’s Council delivered three fantastic Lecture Luncheons throughout the year at which Texas Biomed scientists Dr. Marie-Claire Gauduin, Dr. Ian Cheeseman and Dr. Jordi Torrelles shared their cutting-edge research with our membership and prospective new members. In March of last year, members enjoyed the premiere event, Dining and Discourse, where scientists joined a table of guests in an intimate setting for dinner at The Argyle, allowing for candid conversations around their areas of expertise. In May, we and our prospective members were fortunate to enjoy an informative VIP tour of the Texas Biomed campus, and in October, we hosted a new member event at La Fonda on Main. We especially thank our event sponsors who underwrite 100 percent of our event costs, allowing the Founder’s Council to contribute more substantially to our equipment grants. We concluded 2018 with a holiday party at Dacia and Lanham Napier’s home and were honored to present Dr. Joanne Turner, Vice President for Research for Texas Biomed, with equipment grant awards totaling more than $97,000. The Founder’s Council exists to educate its members about life-changing research conducted every day at Texas Biomed, to empower our members, then to educate their communities and colleagues about the Institute’s efforts and strides. It is our sincerest hope, that once informed, these community leaders also will financially support Texas Biomed so that it may continue for generations its noble and necessary science. This year played a vital role in helping Texas Biomed make a global impact, and we are honored to carry on this distinguished tradition. At the service of Texas Biomed, Trey Dawson, 2018 President, Founder’s Council


2018 FOUNDER’S COUNCIL EXPLORERS

ADVENTURERS

Mr. and Mrs. Brett Alvheim Mr. and Mrs. Aaron Asel Mr. and Mrs. Jeff P. Bailey Mr. and Mrs. Jonathon Beitz Mr. and Mrs. Matthew M. Bell Mr. and Mrs. Ryan Berg Mr. J. Craig Browning, Jr. Mr. and Mrs. John Brozovich Mr. and Mrs. Trey Dawson Mr. and Mrs. Jeffrey de Rojas Mr. and Mrs. John W. Feik, Jr. Mr. Robert H. Finney and Dr. Nancy A. Finney Mr. and Mrs. Craig J. Garansuay Mr. and Mrs. David Gard Mr. and Mrs. Evan and Renee Gerald Mr. Jonathan Hess Mr. and Mrs. Benjamin B. Holliday Mr. and Mrs. Charles R. Hollimon Mr. and Mrs. Andrew Hunt Mr. and Mrs. Tony C. Johnson Mr. and Mrs. Byron L. LeFlore, Jr. Mr. and Mrs. David G. Lloyd, Jr. Mr. and Mrs. Taylor Little Mr. and Mrs. Madison C. Marceau Mr. and Mrs. Charles G. Martens Mr. and Mrs. David Mauze Mr. and Mrs. Madison Mauze Mr. and Mrs. Chance Mazurek Mr. and Mrs. Alexander S. McAllister Mr. and Mrs. David McArthur Mr. and Mrs. Joe Miller Ms. Evangeline Myers Mr. and Mrs. Scott Nathan Mr. Robert Ochoa Mr. and Mrs. Gardner Peavy Mr. and Mrs. Andrew B. Price Dr. and Mrs. Antonio Serna IV Mr. Trevor Lawton and Ms. Amy Stinson Mr. and Mrs. Conrad “Rad” Weaver Dr. Alexis Wiesenthal Mr. and Mrs. George J. Wommack

Mr. and Mrs. Scott Fraser Anderson Mr. and Mrs. Brian and Emmy Ballantyne Mr. and Mrs. R. Bruce Walker Mr and Mrs. Charles Conner Mr. and Mrs. Alex Childers Mr. Mark De Hoyos Mr. and Mrs. Albert Dickson Mr. and Mrs. Kenneth Dorbandt Mr. and Mrs. Marty Dusek Mr. and Mrs. Andrew T. Friedman Mr. and Mrs. Casey Fry Mr. Sean Galligan Mr. and Mrs. Lane Golden Mr. and Mrs. James B. Griffin Mr. Carlo Gutierrez Mr. and Mrs. William Kothmann Mr. and Mrs. Daniel Lasater Mr. Andrew J. Lewis IV Mr. and Ms. Will Newburn Mr. and Mrs. Kyle Palmer Mr. Krishna Reddy Ms. Katie Reynolds Mr. and Mrs. J.B. Richter Mr. and Mrs. Paul A. Rohlfs, Jr. Mr. and Mrs. Robert Shaw Mr. and Mrs. Paxton Jordan Smith Mr. and Mrs. Mellick Sykes, Jr. Mr. and Mrs. Robert Turnbull Mr. and Mrs. Marc Whyte Mr. and Mrs. Scott Wiggans Mr. Steven Frederick Willson

MEMBERS Ms. Selena Aleman Mr. and Mrs. Landon Anderson Mr. Suhail Arastu Mr. and Mrs. Scott Archer Mr. and Mrs. Joe Ashby Mr. and Mrs. Matthew Badders Mr. and Mrs. Tom Bagby III Mr. John W. Ballantyne

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Mr. and Mrs. Edward Bartolomei Mr. and Mrs. Brad Beldon Mr. and Mrs. Joshua Berg Mr. and Mrs. Greg Bolner Mr. and Mrs. Forrest Bowman Mr. Kyle Braaten Mr. and Mrs. William A. Brooks Mr. Jeffrey Brouillard Ms. Cheryl Burkhardt Mr. and Mrs. Aldes H. Cadwallader V Mr. and Mrs. Andrew and Sara Cardwell Dr. and Mrs. McCurdy Cardwell Mr. Brandon Carpenter Mr. and Mrs. Bradley Carson Mr. Paul B. Carter Mr. and Mrs. Stuart Carter Mr. Robert M. Cavender Jr. Mr. and Mrs. James Chandler Mr. and Mrs. Brandon Clementson Mr. Andrew R. Craig Ms. Kalyn Davidson Dr. Susie DeKoch Mr. and Mrs. Jay Dewald Ms. Nancy Hanks Dewar Mr. and Mrs. Taylor Dorris Mr. and Mrs. Robert A. Dullnig Mr. Will Fawcett Mr. and Mrs. Johnny Fitzsimons Mr. and Mrs. Chase Gorman Mr. and Mrs. Ryan Griffin Mr. and Mrs. Roger C. Hill III Mr. and Mrs. Charles M. Hornberger Mr. and Mrs. David Hornberger Mr. and Mrs. Anson and Meredith Howard Mr. and Mrs. Joel Hoyt Mr. and Mrs. Robert Jones Mr. and Mrs. Phil Kandera Mr. and Mrs. Clifton Karam Mr. and Mrs. Matthew Koehler Mr. and Mrs. Parker LaBarge Dr. and Mrs. Brian Langford Mr. and Mrs. Colby Lewis Mr. and Mrs. Alcide M. Longoria Mr. and Mrs. Peter Mako


Mr. and Mrs. Chance Mazurek Mr. and Mrs. William L. McCamish Mr. Robert T. McCullough Mr. and Mrs. R.W. McDonald Mr. and Mrs. Brad McMurray Ms. Catriona L. Morrison Mr. and Mrs. Brian O’Gorman Mr. and Mrs. Ross and Whitney Ormond Mr. and Mrs. Kyle Palmer Mr & Mrs Tres Peacock Mr. Benjamin Pilgrimww Mr. and Mrs. Jack Marshall Porterfield Judge Carla Martinez Riedl Ms. Kylee Robinson Mr. and Mrs. Patrick Rouse Mr. and Mrs. Conner Ryan Mr. and Mrs. Wes Sharples Mr. Jonathon R. Schneider Mr. and Mrs. Bryan Schones Mr. and Mrs. Robert Webb Sellers, Jr. Ms. Abigail Shaver Mr. Ty Hunter Sheehan Mr. and Mrs. Alan Spalten Mr. and Ms. Blake Stouffer Ms. Delaney Tholen Mr. and Mrs. Frederick Thomson IV Mr. Hunter Thunell Mr. and Mrs. Matt Toohey Mrs. Paula Waggoner-Aguilar Drs. Christopher and Kathryn Walker Mr. and Mrs. Bart Waters Mr. and Mrs. Robert Watson, Jr. Mr. Barkley Wedemeyer Mr. and Mrs. William Daniel Westmoreland Dr. Alison Wiesenthal Mr. and Mrs. Brandon Williams Mr. and Mrs. James Y. Williams Mr. Ben Wilson Mr. Cole Wollak and Ms. Aysun Bal Mr. and Mrs. Elgin Wong Mr. and Mrs. John H. Wright IV Mr. and Mrs. David S. Zachry Mr. and Mrs. Will F. Ziegler

CORPORATIONS/SPONSORS Advantage Pain Management Mr. Andrew Conquest Dr. Sarah Trampota Conquest Asel & Associates, PLLC Mr. Aaron Asel Mr. John Asel

Milam Real Estate Capital, LLC Mrs. Burkley Fitzsimons Mr. Vincent Dawson MW Construction Mr. Maurice L. Williams Nelson Puett Foundation Mrs. Callie Puett Price

BB&T Ms. Stephanie Dick Mr. Ben Pressentin

Pape-Dawson Engineers, Inc. Mr. Trey Dawson Mr. Taylor Dawson

Broadway Bank Wealth Management Mr. Robert Ochoa Mrs. Elizabeth Hetrick

Project Control of Texas, Inc. Mr. Andrew Hunt Mr. John Duhrig

Broussard Group Mr. and Mrs. Bret E. Brossard

RSM US LLP Ms. Josie Behrend Ms. Vicky Martin

Brown & Ortiz, P.C. Mr. James B. Griffin

RVK Architects Mr. Heath Wenrich Mr. Jason Puchot

Cardno Structural Engineers Ms. Lauren Setterbo Mr. David Carter

Silver Eagle Distributors, L.P. Ms. Katie Reynolds Mr. Mark De Hoyos

DuWest Realty Mr. Evan Ketabchi

SpawGlass Mr. Jason Smith Ms. Stephanie Dixon

Frost Mrs. Mallony Ahl Mrs. Mary Stephanie Looke

The Bank of San Antonio Mr. Jordan Booth Ms. Kacy Smith

Guido Construction Mr. Cosmo F. Guido Mr. Ted Zimmerhanzel IBC Bank Mrs. Jennifer Martinez MuenChow Mr. Bernando De la Garza Jackson Walker, LLP Ms. Lauren Ciminello Ms. Alexine Freidman

The Tobin Endowment Mr. J. Bruce Bugg, Jr. Transpecos Banks Mr. George Mussleman Mr. Matthew McLaughlin Whataburger Mrs. Linda Benavides Ms. Kim Harle

Joeris General Contractors Mr. Gary Joeris Mr. Jeff Bryant

Worth & Associates Mr. Robert Clinton Worth

JPMorgan Chase Ms. Michele Camp Lechugilla Ventures Mr. and Mrs. John C. Moorman Marsh Wortham Mr. Charles Hollimon McNelis + Associates Mr. Richard McSwain Mr. Sean B. McNelis

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Yantis Company Mr. Todd Compton Mr. Mike Yantis Zachry Group Mr. Rode Moore Mr. David Schwab


The

ARGYLE

T

Substance and Style

he Argyle is a stately mansion in Alamo Heights that stands as a symbol of a rich past and an inspirational purpose: to support, encourage and foster scientific discovery at Texas Biomed. The private club is the platform for a decades-old relationship between Texas Biomed and those who give their time and money to support the Institute. Each member of The Argyle helps fund the future of research with annual contributions to advance the studies conducted by Texas Biomed scientists.

In 2018, The Argyle celebrated a second year with the status of Distinguished Club. This prestigious designation from BoardRoom magazine is a reflection of the excellent member experience which resulted in increased club membership and club usage. Roughly 4% of the 4,000 private clubs nationwide have an active waitlist and The Argyle is one of them. Lectures from scientists at Texas Biomed drew crowds during 2018, increasing the level of club engagement. During the Fireside Chats, audiences learned about many headline-making topics including “The Buzz About Zika: New Cautionary Research” and “100 Years Since the Spanish Flu Pandemic: Are We Safer?” Member contributors — the Coates Charitable Foundation and Elizabeth Huth Coates Charitable Foundation — are funding some stylish upgrades to the 19th century building. The Argyle is focused on the future with the creation of a new addition — the Coates Tavern — which will become one of the most beautiful and desirable business casual bars in San Antonio and beyond. In an effort to improve the experience of club members, 2018 saw an investment from a generous donation from Ron and Karen Herrmann and their family that will improve access and provide new parking. With eyes trained on the future, The Argyle is expanding the club’s capacity by 15 percent and attracting a younger demographic. With substance and style, this warm and inviting venue is on track to provide excellent dining in unique surroundings for decades to come.

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Officers of the Institution and Senior Administrators President and Chief Executive Officer Larry Schlesinger, M.D.

Vice President for Research Joanne Turner, Ph.D.

Vice President for Finance and Administration and Chief Financial Officer Bruce Edwards

Vice President for Advancement and Public Relations Corbett Christie

Vice President for Information Technology and Chief Technology Officer John M. Heaner Director, Southwest National Primate Research Center Deepak Kaushal, Ph.D.

Acknowledgments CREDITS

Copyright © 2018 Texas Biomedical Research Institute P.O. Box 760549 San Antonio, Texas 78245

Lisa Cruz, Assistant Vice President for Communications, Editor

The 2018 Annual Report is a publication of the Texas Biomedical Research Institute.

Jeffrey Heinke Design, Design

*Board of Trustees and Senior Administrators listed for 2018-2019

Wendy Rigby, Media and Communications Specialist, Writer and Assistant Editor Callie Rainosek, Graduate Writing Intern for Deepak Kaushal, Ph.D. and Community Outreach

PHOTOGRAPHY Josh Hushkin, pp 6, 9, 13, 18 Wendy Rigby, p 16 Jeffrey Heinke, pp 32-33 File photos, all other pages


TEXAS BIOMEDICAL RESEARCH INSTITUTE P.O. BOX 760549 SAN ANTONIO, TEXAS 78245 www.txbiomed.org 210.258.9400


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