TargetCool Boosting Mode

TargetCool Product Overview

What Is TargetCool?

• FDA cleared, Portable, Class II medical device.

• Handheld device with 3 interchangeable nozzles that each unlock unique treatment modalities for the provider, used in combination with consumables.

o Cooling mode

o Freezing mode

o Boosting Mode

The Science Behind the Device

CO2 Evolution with TargetCool

Historically, CO2 has been uncontrolled. With TargetCool , the CO2 is controlled before contacting dermis allowing the provider to have unique precision

TargetCool adjusts the thermodynamic state of CO2, changing the nature of the CO2 itself. This allows user to control skin temperature by manually adjusting the distance and timing of cooling jet

As a result, precise, rapid cooling is achieved

TargetCool Boosting

TargetCool Boosting Uniformly

Delivers to the Dermal-Epidermal

Junction

• TargetCool Boosting Mode allows solution delivery down to Dermal Epidermal Junction (DEJ)

• Solution is instantly cryo-frozen into microparticles and accelerated by a high-velocity CO2 jet

• High-speed cryo-frozen micro-particles are sprayed onto the skin and, when paired with barrier-disrupting treatments, such as microneedling can be uniformly delivered onto the skin while reducing inflammation and discomfort from the treatment.

*The thickness of the skin can vary in different areas. Here is a general overview of the approximate thickness of the

facial skin layers

Higher Efficacy associated with Microneedling

• Higher absorption when using microneedling in combination with TargetCool compared with microneedling alone.

Microneedling Only

VS.

Microneedling + TargetCool

Proven effect of TargetCool’s solution delivery

• Absorption level was higher when using TargetCool Boosting compared to microneedling alone.

Solution Detection Imaging Results from In Vivo Animal Skin Tissue

• With a single TargetCool boosting treatment, there's notably higher absorption observed compared to microneedling.

Controlled: Topical Application

Microneedling only

Microneedling + TargetCool

TargetCool Boosting Components

Boosting Container

Cartridge filter

CO2 Cartridge

TargetCool In A Clinical Setting

Hair Restoration – Exosomes Case Study Patient #1

● 58 y/o F

● Thinning potentially d/t covid & Age related hormonal changes.

● 1 TX of Resilielle 10Bil Exosomes applied with TargetCool Boosting.

● Image 25 days apart.

Hair Restoration – Exosomes Case Study Patient #2

● 67 y/o M

● Thinning potentially d/t age & genetic related issues.

● 1 TX of Resilielle 10Bil Exosomes applied with TargetCool Boosting.

● Image 30 days apart

Hair Restoration – Exosomes Case Study Patient #3

● 53 y/o M

● Thinning potentially d/t age & genetic related issues with a family H/O male pattern balding.

● 1 TX of Resilielle 10Bil Exosomes applied with TargetCool Boosting.

● Image 30 days apart.

Practice Integration

• With the 3 different modalities of this device practice integration is easy.

• Freezing mode (cryo) can be used for warts and skin tag removal.

• Cooling mode is used to decrease pain associated with treatments such as PRP, filler, neurotoxin, and skin boosters. This is also a great way to reduce bruising by way of vasoconstriction.

• Boosting mode can be used with serums such as exosomes, skin boosters, hyaluronic acid and lidocaine.

Revenue Generating Device

• Faster treatments increase the number of patients providers can see per hour.

• Pain free option for patients who are needle phobic.

• 3-in-1 modality device in the palm of your hand to increase your revenue per office visit.

• Provides new and innovative treatment options and easy to delegate.

Treatment Package: Hair Restoration

Boosting Package Pricing

Package of 3: $1500

Cost of Goods: $108

• $45 CO2 canister + boosting cartridge

• $63 Age Zero Exosome Serum

Total Cost of Treatment:

• $108 x 3 = $324

• $1,176 profit per package

Profit Per Single Treatment:

• $550 - $108 = $442 (15min total treatment time)

• 5 treatments per week = $2,210

• Month: $8,840

• Annually: $106,080

Treatment Package: Restore Facial

Boosting Package Pricing

Package of 3: $1,000

Cost of Goods: $108

• $45 CO2 canister + boosting cartridge

• $63 Age Zero Exosome Serum

Total Cost of Treatment:

• $108 x 3 = $324

• $676 profit per package

Profit Per Single Treatment:

• $350 - $108 = $242 (15min total treatment time)

• 5 treatments per week $242 = $1,210

• Monthly: $4,840

• Annually: $58,080

• One device with 3 interchangeable nozzles that each unlock unique treatment modalities for the provider

Summary

• Proven Efficacy

• Revenue Generator

Questions

Appendix

Indication & Important Safety Information

INDICATION

TargetCool is indicated for the temporary reduction of pain, swelling, inflammation, and hematoma from minor surgical procedures.

IMPORTANT SAFETY INFORMATION

Do not use the device for patients with cold urticaria, cryopathies such as cryoglobulinemia or cryofibrinogenemia, or paroxysmal cold hemoglobinuria.

Improper use of the TargetCool device may cause personal injury or damage to the system. See the Technical User’s Manual for detailed directions, proper use, and full risk and safety information. For additional product information see www.coolhealth.com

®/TM are trademarks of CoolHealth

Any other product/brand names and/or logos are trademarks of the respective owners.