2025 Stanford OHNS Research Day Booklet

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DETAILS:

MONDAY,SEPTEMBER29,2025I8:00AM-4:00PM

2025OHNSRESEARCHDAYAGENDA

Starttime EndTime Event/Function

7:00AM 8:00AM Breakfast

(NewFacultyPeerMentoringEventBreakout)

8:00AM 8:15AM Introduction:TinaStankovic,MD,PhD

8:15AM 8:25AM DeanLloydMinor,MD(RecordedRemarks)

8:30AM 9:15AM MechanismsofHearing

StefanHeller,PhD,MS,“Multiplepathwayscontrolmitotichaircell regenerationintheavianinnerear”

DáibhidÓMaoiléidigh,PhD,“Howthesensorycellsofhearingwork atphysiologically-relevantsoundfrequencies”

KatharineMiller,PhD,“BridgingtheGaps:NewMethodstoStudy theHairBundleandMechanotransduction”

MatthewFitzgerald,PhD,“AutomaticSpeechRecognitionfor MeasuringAuditoryFunction”

Moderators: Nesrine Benkafadar, PhD, Tracy Cheng,MD,MS

9:15AM 10:00AM CochlearBiology

AlanCheng,MD,“Chenglabandcochlearmacrophagesin2025and beyond”

GraceKim,MD,“Theroleofthecochlearimmunecellsincongenital cytomegalovirus-associatedhearingloss”

TeresaNicolson,PhD,“Rescueofauditorydysfunctioninafish modelofhumanSPENsyndromeusinganFDAapproveddrug”

Moderators: Varsha Athreya, PhD, Lukas Landegger, MD, PhD

10:00AM 10:15AM CoffeeBreak/PosterReview

10:15AM 11:00AM ImageGuidedSurgery

FredBaik,MD,“AugmentedRealityApplicationsinHeadandNeck Surgery”

MichaelChang,MD,“AI-PoweredComputerVisioninEndoscopy”

TulioValdez,MD,MSc,“MolecularImaginginOtolaryngology”

Moderators: Michael Chang, MD, Jacquelyn Callander, MD

11:00AM 12:00PM

KeynoteSpeaker:YuriAgrawal,MD,MPH,“Vestibularlossand cognitioninagingadults”

(IntroductionbyTinaStankovic,MD,PhD)

Starttime EndTime Event/Function

12:00PM 1:00PM LunchandPosterReview

(KeynoteSpeakerlunchwithtrainees)

1:00PM 1:45PM CancerBiology&ClinicalTrials

NathanReticker-Flynn,PhD,“Immuneselectivepressuresdrivethe evolutionoftissue-specificdivergentmetastaticphenotypes”

ChrisHolsinger,MD,“Long-termResultsofECOG3311:ConfirmingtheRole ofFrontlineSurgeryforHPV+OropharyngealCancer”

AndreyFinegersh,MD,PhD,“Uncoveringchromatinregulationofheadand neckcancercellmetabolism”

JohnSunwoo,MD,“Tissue-ResidentNKCellsandDevelopmentofCellular ImmunotherapyStrategiesforSolidTumors”

Moderators: John Sunwoo, MD, Emily Zhang, MD

1:45PM 2:30PM PublicHealth&Environment

RobertJackler,MD,“DriversofViralUptakeofElfBarbyUSYouth:Sweet& FruityFlavors,HighNicotine,&ViralSocialMediaMarketing”

UchechukwuMegwalu,MD,MPH,“Understandingdriversofheadandneck cancerdisparities”

LaurenLalakea,MD,“Towardsagreenerfutureinotolaryngology”

KaraMeister,MD,“Characterizationofmicroplasticsinthepediatric immunesystem”

Moderators: Julia Noel, MD, Abdullah AlDaihani, MD

2:30PM 2:45PM CoffeeBreak/PosterReview

2:45PM 3:45PM TissueEngineeringandRegenerativeMedicine

TedMau,MD,PhD,“ConsiderationsandFrontiersintheTreatmentof RecurrentLaryngealNerveInjuries”

ElizabethDiRenzo,PhD,“BreathingThroughtheHaze:InvestigatingPM2.5 EffectsontheLarynx”

JayakarNayak,MD,PhD,“Immune-EpithelialDynamicsandTissue RemodelingandCRSUsingMulti-ScaleTranscriptOmics”

ZaraPatel,MD,“RegenerationoftheOlfactoryEpitheliumandBeyond”

Moderators: Jon-Paul Pepper, MD, Tatiana Correa, MD

3:45PM 4:00PM ClosingRemarks,PosterWinnerAnnouncements

4:00PM 5:00PM Refreshments,Socialize,andPosterReview

1

BASICPOSTERPRESENTATIONS

AyseMarasliogluSperber

CochlearInjuryReporgramstheCellularTropismofSyntheticAAV Vectors* 2

3

4

5

YaoGao

SaraBillings

JesusMaldonado

YingkunYang

JunHe

AssociationofGlialCellswithSensorimotorDefectsinZebrafishspen Mutants

Spatialtranscriptomicanalysisrevealsmechanismsofcochlearhair cellregenerationandmaturation

UsingPosteriorSemicircularCanalInjectionstoCreateaNovelModel forStudyingtheOtotoxicityofSisomicinandN1MS

Characterizingamulti-dosekanamycinototoxicitymousemodel

GSK3β–EGF–TGFβCrosstalkDrivesVestibularSupportingCell Proliferation 7

SriramHemachandran

Assessingthecognitivedeclineposthearinglossindiphtheriatoxin deafnessmodel 8

TracyCheng

RegenerationofHairCellsbyCo-ExpressionofGfi1,Atoh1,andPou4f3 intheAdultMouseCochleaAfterAminoglycosideInducedDamage

Voltage-DrivenBundleMotioninHairCellsDependsontheMET Complex

DeterminantsofthePediatricNasalMicrobiomeinBangladesh:An AntibioticFocus

LATSKinaseInhibitionInducesCellCycleRe-EntryofPostmitotic SupportingCellsinMouseInnerEarOrganoidsviaYAPNuclear Translocation

DivergentModesofHairBundleMaturationintheMouseUtricle

SpeedingUpSimulationsofOuter-Hair-CellBundlesUsingArtificial Intelligence

EpithelialandMesenchymalWntsRegulateSensoryCellSpecification andOrganizationduringCochlearDevelopment

DefectsinExosomeBiogenesisAreAssociatedwithSensorimotor DefectsinZebrafishvps4aMutants

LINKSREGULATEDEFLECTIONFLUCTUATIONSINTHESENSORYCELLS

ACTL6AregulatestheWarburgeffectthroughcoordinatedactivation ofAP-1signalinginheadandnecksquamouscellcarcinoma*

Histopathologicchangesinthelarynxandsubglottisinmiceexposed toPM2.5

CharacterizingHeterogeneityofMechanotransductionChannelsin MouseandHumanUtricles

DetectingIndividualAuditoryBrainstemResponses(ABRs)*

CLINICALPOSTERPRESENTATIONS

Data-DrivenClassificationofAudiometricPhenotypesLinkedto SpeechPerceptioninQuietandNoise

Maximizer-minimizerpreferencesinlaryngealsquamouscell carcinoma

ARscope:AugmentedReality–EnhancedMicroscopeforOtologic Microsurgery

ShannonWu

ShannonWu

ElaineCosta

AnthonyNewman

PeterMoon

BarriersandFacilitatorsofFinancialHardshipinHeadandNeck Cancer

ThePatientSeekingVestibularCare:Signalsfrom515IntakeSurveys ataTertiaryNeurologyCenter

ApplicationsofSuperLearnerAlgorithminPredictingOutcomesin HeadandNeckSquamousCellCarcinoma(HNSCC)

UpperAirwaySurgeryforObstructiveSleepApneainOlderAdults: CardiovascularandEndocrineOutcomes

UtilityofComputedTomographyandRadiographicImaginginIsolated NasalBoneFractures

DemographicAnalysisofFallRiskMeasuredbyAIHearingAIds

ExploringFacialAsymmetryMetricsCorrelatedwithPreoperative SCHNOSScoresUsingAI

ANoseforClinicalReasoning?AssessingLargeLanguageModel PerformanceinOtolaryngologySurgicalPlanning

EvaluatingPreoperativeGLP-1TherapyinObstructiveSleepApnea: InsightsfromReal-WorldData

TrueDepthBringsLongitudinal3DPrecisiontoFacialPalsyMonitoring

Long-termSinonasalOutcomesinPatientswithAcuteInvasiveFungal Sinusitis* 15 EdwardDamrose

ChemicallyInducedVoiceRest-TheRoleofBotulinumToxinIn LaryngealHealing

Retropharyngealvascularmalformations-Anunderrecognizedcause ofglobuspharyngeus 17 MaxwellLee

ImpactofBeersCriteriaMedicationsinElderlyPatientswithHeadand NeckCancer

WewouldalsoliketothankourPosterJudges:

Basic/TranslationalResearch:NesrineBenkafadar,PhD,GraceKim,MD,LukasLandegger,MD,KaraMeister, MD,NathanReticker-Flynn,PhD

ClinicalResearch:JenniferAlyono,MD,NoelAyoub,MD,SethDavis,MD,JakeLee,MD,TristanTham,MD

YuriAgrawal,MD,MPH isProfessorandChairoftheDepartment ofOtolaryngology-HeadandNeckSurgeryattheUniversityof ColoradoSchoolofMedicine.SheisanOtologist-Neurotologist, andhasseveralNIHgrantsstudyingvestibularlossandcognition inolderadults.SheservesastheEducationDirectorofthe AmericanNeurotologySociety,aDirectorontheAmerican AcademyofOtolaryngology’sBoardofDirectors,CouncilMember oftheAmericanBoardofOtolaryngology,Treasurer-Electofthe TriologicalSociety,andPast-PresidentoftheAssociationfor ResearchinOtolaryngology.

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2025 Stanford OHNS Research Day Booklet by Stanford OHNS - Issuu