VENTURE SPRIND 2026 Booklet

April 14, 2026

Futurium Berlin

A SPRUNGINNOVATION IS AN INNOVATION, THAT CHANGES OUR LIVES FOR THE BETTER IN THE LONG TERM.

IT CAN CREATE A COMPLETELY NEW MARKET, FUNDAMENTALLY CHANGE AN EXISTING MARKET TO CREATE A COMPLETELY NEW ECOSYSTEM, OR SOLVE A MASSIVE TECHNOLOGICAL, SOCIAL OR ENVIRONMENTAL PROBLEM.

SPRIND PROVIDES CUSTOM MADE FUNDING

SPRIND IS SEARCHING FOR WAYS TO OVERCOME THE SOCIAL, ENVIRONMENTAL AND ECONOMIC CHALLENGES OF OUR TIME. SUPPORT OF SPRIND IS COMPREHENSIVE. WE FINANCE, COACH AND PROVIDE STRONG NETWORKS FROM FROM SCIENCE, BUSINESS AND POLITICS.

SPRIND FUNDING INSTRUMENTS START-UP FUNDING Through start-up funding, we support young companies that are not yet able to acquire sufficient funding from private sources. We use the start-up funding to build up the company, develop the technology and, if necessary, take the first steps towards commercialization.

Funding is provided up to EUR 1 million.

INVESTMENTS AND CONVERTIBLE LOANS If the private venture capital market does not offer sufficient financing, we can invest directly in start-ups. New private investors must provide at least 30% of the financing round and, as lead investor, negotiate the terms on which SPRIND will then invest on an equal footing. We can use equity investments, convertible loans and any other instruments similar to equity investments.

FUNDING FOR RESEARCH AND DEVELOPMENT We support disruptive innovations during capital-intensive research and development stages and fund part of the development costs. The remaining costs are covered by private investments. Our funding is typically in the single-digit million euro range, although it can reach up to EUR 35 million in individual cases. SPRIND funding only has to be repaid in the event of success, in other words, if the start-up goes public, is sold or begins to distribute profits.

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SPRIND CHALLENGES In the SPRIND challenges, teams with disruptive innovation potential currently receive between EUR 500,000 and three million per competition stage. Funding is provided as a pre-commercial contract for research and development.

SPRIND FUNKEN Every SPRIND Funke can be a small step towards great transformations. Like the challenges, the sparks are innovation competitions for pioneers with world-changing ideas – but even faster. Currently, teams receive up to EUR 350,000 per competition stage. As with the SPRIND challenges, funding is provided via pre-commercial contracts.

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VENTURE SPRIND COMPUTA COMPUTE INFRASTRUCTURE

ALGORA

Semiconductors, chips and highperformance computing architectures powering next-generation digital and AI capabilities.

ARTIFICIAL INTELLIGENCE Artificial intelligence transforming everything from daily tasks to life sciences and robotics.

This transformation must be safe, secure, and resource-efficient.

Semiconductors, Chips, High-Performance Computing, Compute Infrastructure, Digital Sovereignty

Physical intelligence, Composite Learning, Deepfake Detection, Agent-Economy, Efficient AI

MATERIA NEXT-GEN MATERIALS Materials and chemical processes that actively remove waste and enable sustainable, circular industry at scale.

STELLA AEROSPACE & RESILIENCE

Circular Materials, Advanced Materials, Sustainable Chemistry

Space and aerospace technologies to protect Europe‘s sovereignty, resilience, and strategic autonomy.

Space Systems, Satellites, Defense Tech, Security

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UNIVERSE ENERGIA FUTURE ENERGY Next-generation energy systems powering a climate-neutral, resilient, and competitive Europe.

Renewables, Hydrogen, Storage, Smart Grids

FACTURA INDUSTRIAL INNOVATION Industrial innovation that decarbonizes production while strengthening Europe‘s competitiveness.

Clean Manufacturing, Decarbonization, Robotics, Agriculture Technologies

VITALA ADVANCED MEDICINE Breakthrough therapies transforming how serious and currently untreatable diseases are addressed.

Advanced Therapies, Biotech, Gene & Cell Therapy

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CONTENT COMPUTA BLACK SEMICONDUCTOR. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 EWIGBYTE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 GIXEL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1% INCIRT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . &0 NEQXT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . && NEUROMORPHIC FIBER NETWORKS . . . . . . . . . . . . &4 OPEN RADIO SYSTEMS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . &6 PIXEL PHOTONICS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . &% QUSINE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30 SEMRON . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3&

VITALA AATEC . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34 BIOPEPLEACH . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36 BIOTX.AI . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3% BRAINQR THERAPEUTICS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40 CELLBRICKS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4& CINGULUSBIO. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 44 CONNCONS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46 CPTX. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4% DENAZYME . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50 INCEPHALO THERAPEUTICS . . . . . . . . . . . . . . . . . . . . . . . . . . 5& INGINEEON . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54 KANO THERAPEUTICS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56 LIMAA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5% METAIMMUNE THERAPEUTICS . . . . . . . . . . . . . . . . . . . . . . 60 PANOSOME . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6& PRINNOVATION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64 SNIPR BIOME . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 66 SURFACTOBIOTECH . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6% SYDRA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70 SYMBIOTICA THERAPEUTICS . . . . . . . . . . . . . . . . . . . . . . . . . 7& TQ THERAPEUTICS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 74 TRANSMUTEX . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 76 ULTRABRIGHT BIOTECH . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7% UNOMR . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . %0 VIFERAXS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . %&

CONTENT MATERIA AEVOLOOP . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . %4 AMPHICO . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . %6 AMPHISTAR (SURFACYCLE, . . . . . . . . . . . . . . . . . . . . . . . . . . . . %% BIOPHELION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . -0 BIOTREASURE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . -& BIOXTRACT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . -4 BLUU . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . -6 C3 BIOTECHNOLOGIES. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . -% CELLX BIOSOLUTIONS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100 CMETRE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10& COLIPI . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 104 DESCYCLE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 106 EMPYRIO . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10% E-MURGY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 110 EVERYCARBON . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11& FOOM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 114 HYDRODESAL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 116 ING3D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11% LANTHACYCLE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1&0 LEVEL NINE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1&& LIGNILABS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1&4 MIMOTYPE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1&6 OLIMENT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1&% TURBOO. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 130 WEEEFFICIENT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13& WESORT.AI . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 134

ALGORA AURYAL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 136 EXALSIUS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13% IT‘S REAL.MEDIA. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 140 METABUILD . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14& MIMIR . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 144 NEOBIM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 146 NEOCLEAR . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14% PANOCULAR.AI . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 150 PLANETARY COMPUTE PROTOCOL . . . . . . . . . . . . . . . 15& RULEMAPPING . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 154 WEIGHT SPACE LABS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 156

CONTENT ENERGIA %INKS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15% BATENE. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 160 CARBON.ONE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16& ELEMENTARHY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 164 GREENLYTE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 166 MACROCARBON . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16% RADICAL DOT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 170 SHIT&POWER . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17& TELURA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 174 VIRIDIS RECYCLING . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 176 WATER STUFF & SUN . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17%

FACTURA ABSORA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1%0 AEON ROBOTICS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1%& BOROBOTICS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1%4 CONTINUUM INNOVATION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1%6 ENADYNE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1%% FLUIDECT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1-0 HUMIFY. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1-& ILLUTHERM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1-4 INFRASONIK . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1-6 MAGNOTHERM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1-% MICROBUBBLES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . &00 MUNIQO PERFORMANTE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . &0& POLYBOT. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . &04 FOCUSED ENERGY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . &06 SYMBIOTIC GREEN TECHNOLOGIES. . . . . . . . . . . . . &0% WELDNOVA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . &10

CONTENT STELLA AETOSPHERE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . &1& AVIENTUS RADNAV . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . &14 CDDS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . &16 GETWING. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . &1% HYPERSONICA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . &&0 NEUROSPACE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . &&& NEWORBIT SPACE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . &&4 NOUMA AUTONOMY. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . &&6 POLARIS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . &&% UBASWARM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . &30 ZETATOR . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . &3&

Please bear with us and note that all content in this booklet has been provided by the teams themselves. It does not claim to be complete or perfect, but is intended as a helpful overview.

If you come across a typo or a number that seems unusual, feel free to reach out to the respective team — it’s a great way to start a conversation.

As this booklet was produced with limited resources — and as you may know, even one of the earliest “Sprunginnovationen,” the printing press, still depends on strict deadlines — not all teams currently present at VENTURE SPRIND may be featured.

BLACK SEMICONDUCTOR BLK IS DEVELOPING A NEW TYPE OF COMPUTER CHIP TECHNOLOGY THAT ENABLES A STEP CHANGE IN AI PERFORMANCE. THIS IS ACHIEVED THROUGH THE &D MATERIAL GRAPHENE. COMPUTE INFRASTRUCTURE

COMPANY DETAILS LOCATION Aachen, Germany

ESTABLISHED YES

WEBSITE www.blacksemi.com

TRL TRL 4

PATENTS GRANTED 52

EMPLOYEES 130

FUNDING DETAILS FUNDING STAGE SERIES B

FUNDING NEEDED 1&5,000,000 EUR

REVENUE 700,000 EUR

PRIVATE FUNDING 3,750,000 EUR

PRIVATE FUNDING - EU 3%,000,000 EUR

PUBLIC FUNDING &&7,%00,000 EUR

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Humans communicating via letters is slow and inefficient, imagine our brains were directly connected – how much faster we could move forward.

That’s what we do with computer chips, connecting chips with each other using integrated graphene photonics. We developed this chip technology and build a fab for volume production.

COMPUTA

For AI to go where we all hope for, we need dramatically cheaper cost per token, not possible with todays technology. The solution is a new category of computer chip: an electric-optical chip - which operates electrical but speaks optical. This allows a thousand times better performance and reduces cost per token.

VITALA

APPROACH

STATUS Black Semiconductor received almost EUR 280 Mio. to turn 20 years of research into Europe’s next chip champion. We now raise a EUR 125 Mio. Series B used to commercialize AI connectivity, scale IP, and ramp 300 mm integrated graphene photonics to volume production.

ALGORA

MATERIA

MOTIVATION

Cedric Huyghebaert

Ogi Brkic

FACTURA

Sebastian Schall

STELLA

Daniel Schall

ENERGIA

TEAM

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EWIGBYTE EWIGBYTE IS DEVELOPING GROUNDBREAKING TECHNOLOGY FOR THE LONG-TERM STORAGE OF DATA ON GLASS. COMPUTE INFRASTRUCTURE

COMPANY DETAILS LOCATION Poecking, Germany

ESTABLISHED YES

TRL TRL 6

EMPLOYEES 5

WEBSITE www.ewigbyte.com

FUNDING DETAILS FUNDING STAGE PRE-SEED

FUNDING NEEDED 5,000,000 EUR

16

PRIVATE FUNDING - EU 1,600,000 EUR

We envision to build a new „Layer of Permanence“: the new infrastructure for data that must endure forever.

Data written with light, held in glass.

Beyond heat, energy consumption, time, or attack.

A data storage layer build for continuance.

We offer data writing, storing and reading as a service in our future glass data centers.

COMPUTA

APPROACH

STATUS The MVP to write, store, and read data blocks of up to 500 TB is being assembled . We will be able to write first customer pilots starting September 2026.

Three patents are in the process of filing.

Two founders and a newly hired Head of Business Development build a pipeline of beachhead customers and develop a re-sale partner network.

ALGORA

MATERIA

VITALA

MOTIVATION

Phil Wittwer

FACTURA

Steffen Klewitz

STELLA

Ina Dorothee von Haeften

ENERGIA

TEAM

17

GIXEL GIXEL REVOLUTIONIZES AR DISPLAYS WITH HIGH-EFFICIENCY, RETINA-QUALITY VISUALS FOR AIPOWERED GLASSES. COMPUTE INFRASTRUCTURE

COMPANY DETAILS LOCATION Karlsruhe, Germany

ESTABLISHED YES

WEBSITE www.gixel.de

TRL TRL 4

PATENTS GRANTED 7

EMPLOYEES 15

FUNDING DETAILS FUNDING STAGE SERIES A

REVENUE 6&0,000 EUR

PRIVATE FUNDING - EU 1,&&5,000 EUR

18

PRIVATE FUNDING -&0,000 EUR

The pupil moves.

Today’s AR displays send light to many possible eye positions — wasting more than 99% of the light.

Gixel tracks the pupil and sends light only to the eye.

Result: dramatically higher efficiency and bright AR in glasses.

COMPUTA

AI glasses are taking off. ~10M units are expected in 2025 — already 2! higher than the best forecasts.

But displays remain the bottleneck.

Current AR displays are bulky and inefficient, preventing true glasses form factors. Gixel builds the display technology that enables bright, efficient AR in normal glasses.

VITALA

APPROACH

STATUS Working functional display prototype demonstrated.

Strong technical engagement with leading consumer tech companies.

Next: deliver evaluation kits to Tier-1 OEMs developing next-generation AI glasses.

ALGORA

MATERIA

MOTIVATION

Ding Luo

FACTURA

Felix Nienstaedt

STELLA

Miro Taphanel

ENERGIA

TEAM

19

INCIRT INCIRT DEVELOPS NEXT GENERATION DATA CONVERTERS FOR WIRELESS COMMUNICATION (WIFI, TELCO, SATELLITES, AND RADARS. COMPUTE INFRASTRUCTURE

COMPANY DETAILS LOCATION Aachen, Germany

ESTABLISHED YES

WEBSITE www.incirt.de

TRL TRL 7

PATENTS GRANTED 1

EMPLOYEES 20

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED %,000,000 EUR

20

PRIVATE FUNDING - EU 5,500,000 EUR

We invented a new way to represent signals inside the data converter. This enables complementary parallelization of data conversion across both analog and digital domains, something never done before. We patented the approach and use it to deliver higher performance with lower power.

COMPUTA

Today, data converters are a bottleneck in chipsets for high performance wireless communications such as telecom, satellites, and radar.

Our technology removes this bottleneck, enabling faster communications, higher resolution radar, and more capable systems.

VITALA

APPROACH

STATUS We developed four prototypes reaching TRL 6, all outperforming the state of the art by up to 6x in instantaneous bandwidth while using a fraction of the power.

We are running PoCs with key customers such as Nokia and are part of relevant industry initiatives.

ALGORA

MATERIA

MOTIVATION

Mohamed Saeed Elsayed

FACTURA

Erkan Bayram

STELLA

Oner Hanay

ENERGIA

TEAM

21

NEQXT QUANTUM COMPUTING MADE FOR GERMANY. COMPUTE INFRASTRUCTURE

COMPANY DETAILS LOCATION Erlenbach, Germany

ESTABLISHED YES

TRL TRL 6

EMPLOYEES 51

WEBSITE www.neqxt.org

FUNDING DETAILS FUNDING NEEDED 50,000,000 EUR

REVENUE 3%1,000 EUR

22

PUBLIC FUNDING 1,600,000 EUR

We build and operate a universal ion-trap quantum computer with an almost fully EU-based supply chain and complete infrastructure in Germany. Designed for scalability, our platform will expand to compete globally and secure long-term technological leadership.

COMPUTA

Quantum computing will define security and industrial leadership—from cryptography to pharma and logistics.

Control over this technology is inherently national. We build a sovereign, full-stack EU quantum company, mastering nearly the entire supply chain to ensure secure, independent capability.

VITALA

APPROACH

STATUS Since 2017, we have operated a universal ion-trap quantum computer. Customers such as Bundesdruckerei already use our quantum computing capacity, and under contract with the Cyberagentur we are building a mobile quantum computer to be delivered by 2027.

ALGORA

MATERIA

MOTIVATION

TEAM

FACTURA

ENERGIA

Björn Lekitsch

STELLA

Christian Zimmermann

23

NEUROMORPHIC FIBER NETWORKS IN-SENSOR PROCESSORS USE RESERVOIR COMPUTING WITH POLYMER THREADS ENABLE SELFREGULATING, ENERGY-EFFICIENT BIOLOGICAL SENSING IN THE BODY. COMPUTE INFRASTRUCTURE

COMPANY DETAILS LOCATION Dresden, Germany

ESTABLISHED NO

WEBSITE www.tu-dresden.de

TRL TRL 4

PATENTS GRANTED 2

EMPLOYEES 3

FUNDING DETAILS FUNDING STAGE PRE-SEED

24

We explore physical reservoirs (PRs) based on polymer dendrites for highly efficient computing and connect them to living neurons for synthetic intelligence. Our technology has groundbreaking applications for brain repair & cognitive enhancement.

We build on successful research on neuromorphic computing, using the reservoir computing approach.

Based on biocompatible systems, we address the interface to biological systems.

COMPUTA

APPROACH

MATERIA

VITALA

MOTIVATION

STATUS

ALGORA

Basic functionality demonstrated, Company foundation in preparation.

Andreas Hofacker

Richard Kantelberg

FACTURA

Hans Kleemann

STELLA

Karl Leo

ENERGIA

TEAM

25

OPEN RADIO SYSTEMS OPEN RADIO SYSTEMS BUILDS 6G BASE STATIONS IN SOFTWARE, TRANSFORMING A .500 BILLION GLOBAL MARKET FROM PROPRIETARY HARDWARE TO A HYPERSCALING ECOSYSTEM. COMPUTE INFRASTRUCTURE

COMPANY DETAILS LOCATION Darmstadt, Germany

ESTABLISHED YES

TRL TRL 7

EMPLOYEES 12

WEBSITE

www.openradiosystems.com

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED 1&,000,000 EUR

PUBLIC FUNDING 1,%00,000 EUR

26

PRIVATE FUNDING - EU &37,000 EUR

Our Radio Processing Units (RPUs) enable software base stations to reach carrier-grade performance. They also solve the front-haul bus bottleneck using sub-nanosecond synchronization technology from particle accelerators. This allows conventional computers to outperform proprietary base stations (full of ASICs) from European and Chinese vendors.

COMPUTA

At Open Radio Systems, we transform mobile network infrastructure into software. With our technology, mobile network operators can replace their proprietary 5G/6G base stations by hyperscale datacenters, replacing vendor lock-in with homogeneous hardware, extreme cost efficiency, flexibility, speed, security, and technological sovereignty.

VITALA

APPROACH

STATUS We released our minimum viable product (MVP), the ORS-XC7, in January 2026.

It will be demonstrated in a customer installation in March of this year. We have received several requests for field tests from system integrators and are negotiating at the executive level with tier-one mobile network operators in Germany and the US.

ALGORA

MATERIA

MOTIVATION

Martin Kumm

Stefano Tomasin

FACTURA

Christian Freund

STELLA

Stefan Valentin

ENERGIA

TEAM

27

PIXEL PHOTONICS PIXEL PHOTONICS ENABLES REVOLUTIONARY BREAKTHROUGHS FOR HUMANITY BY SOLVING THE BOTTLENECK OF NIR PHOTON DETECTION. COMPUTE INFRASTRUCTURE

COMPANY DETAILS LOCATION Muenster, Germany

ESTABLISHED YES

WEBSITE www.pixelphotonics.com

TRL TRL 5

PATENTS GRANTED 3

EMPLOYEES 36

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED &,000,000 EUR

PRIVATE FUNDING - EU &,-00,000 EUR

PUBLIC FUNDING 1,500,000 EUR

28

REVENUE 500,000 EUR

Our technology builds on over a decade of development at the University of Münster, combining the advantages of photonic integrated circuits with superconducting thin films and foundry-scale manufacturing methods. This unique combination enables the scalable, cost-effective, and consistent industrial production of top-tier products for deep tech.

COMPUTA

Innovative imaging technologies that enable the early detection of diseases, the monitoring of critical infrastructure, and the protection of communications from malicious actors rely on the high-performance detection of near-infrared light. Current technologies fall short of meeting this need, but Pixel Photonics’ technology solves this problem.

VITALA

APPROACH

STATUS Since our incorporation, we have delivered over a dozen products to customers, with a total value exceeding €3m. In addition, we have acquired four relevant patent families from the university and filed two more patents. We have also secured over €8m in grants from European partners to commercialize our technology and increase our capacity.

ALGORA

MATERIA

MOTIVATION

Fabian Beutel

Christoph Seidenstücker

FACTURA

Wladick Hartmann

STELLA

Nicolai Walter

ENERGIA

TEAM

29

QUSINE QUSINE BUILDS NEXT-GEN ULTRALOW-NOISE SIGNAL GENERATORS IN OPTO-ELECTRONICS – DELIVERING PRECISION FREQUENCIES FOR QUANTUM PHOTONICS, TELECOM, AND ADVANCED MEASUREMENT. COMPUTE INFRASTRUCTURE

COMPANY DETAILS LOCATION Potsdam, Germany

ESTABLISHED YES

TRL TRL 5

EMPLOYEES 9

WEBSITE www.qusine.com

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED &,500,000 EUR

PRIVATE FUNDING - EU 75,000 EUR

PUBLIC FUNDING 1,130,000 EUR

30

REVENUE &10,000 EUR

We develop photonic RF and microwave oscillators that use optical references to generate ultra-low-noise electrical signals. By combining photonics with high-frequency electronics, we achieve record-low phase noise and jitter beyond classical electronics.

COMPUTA

Quantum computing, 6G, radar and satellite systems require ultra-stable, low-noise frequency references.

Existing electronic oscillators limit performance. Our solution enables higher precision, lower error rates and improved system reliability.

VITALA

APPROACH

STATUS Built and validated a photonic microwave oscillator with –154 dBc/Hz phase noise at 10 GHz and femtosecond-level jitter. Awarded Innovation Prize Berlin Brandenburg 2025. Strategic partnership with Fraunhofer HHI and first pilot customer engagements.

ALGORA

MATERIA

MOTIVATION

TEAM

FACTURA

ENERGIA

Saeed Fard

STELLA

Peter Hertenstein

31

SEMRON SEMRON BUILDS 3D FLASH-BASED AI ACCELERATORS THAT INTEGRATE COMPUTE DIRECTLY INTO MEMORY USING ITS NOVEL HIGH-PRECISION MEM-CAPACITIVE SEMICONDUCTOR DEVICE, DELIVERING UNMATCHED INTELLIGENCE DENSITY. COMPUTE INFRASTRUCTURE

COMPANY DETAILS LOCATION Dresden, Germany

ESTABLISHED YES

EMPLOYEES 19

FUNDING DETAILS PUBLIC FUNDING 1,000,000 EUR

32

WEBSITE www.semron.ai

While the density and cost benefits of 3D NAND flash are well known, its use for compute has so far been limited by noise and non-linearity challenges. SEMRON’s approach overcomes these issues through a high-precision mem-capacitive architecture, building on many generations of memory scaling.

COMPUTA

The dependence on DRAM and SRAM limits AI inference hardware to its current performance and cost.

While the industry is constrained to incremental progress, SEMRON takes a leap forward by bringing compute capabilities directly into high-density, low-cost 3D NAND flash, enabled by its patented CapRAM™ technology.

VITALA

APPROACH

STATUS SEMRON is gaining strong momentum as leading memory manufacturers recognize that it has solved challenges they have been unable to address for over a decade. This traction is built on multiple generations of semiconductor prototypes and is secured by a robust and defensible IP portfolio.

ALGORA

MATERIA

MOTIVATION

TEAM

FACTURA

ENERGIA

Tilmann Bartsch

STELLA

Aron Kirschen

33

AATEC DEVELOPING NEW DRUGS FOR RESPIRATORY DISEASES. ADVANCED MEDICINE

COMPANY DETAILS LOCATION Munich, Germany

ESTABLISHED YES

TRL TRL 5

EMPLOYEES 7

WEBSITE www.aatec-medical.com

FUNDING DETAILS FUNDING STAGE SERIES A

FUNDING NEEDED 10,000,000 EUR

PUBLIC FUNDING 1,000,000 EUR

34

PRIVATE FUNDING - EU 4,700,000 EUR

AATec develops therapeutics for lung diseases using a new multimodal approach. Our products are based on a novel version of AAT, a protein that broadly inhibits key mediators of airway inflammation and infections, overcoming the limitations of current treatments. Products are delivered by inhalation for optimal effects in the airways.

COMPUTA

Inflammatory diseases of the airways, such as COPD, bronchiectasis or asthma, affect hundreds of millions of patients worldwide. Current treatment options are limited, and for many patients their disease cannot be adequately controlled. While progress has recently been made by others, the need for broadly effective and safe drugs remains high.

VITALA

APPROACH

STATUS AATec has successfully established the technological basis for the industrial production of the active ingredient and the inhalation device. Extensive data on preclinical efficacy and preclinical safety have been generated. Clinical studies in patients with non-CF bronchiectasis are planned to start in Quarter 3, 2026.

ALGORA

MATERIA

MOTIVATION

Manfred Stangl

FACTURA

Michael Strassmair

STELLA

Rüdiger Jankowsky

ENERGIA

TEAM

35

BIOPEPLEACH THE BIOPEPLEACH TEAM IS BUILDING A BIOHYBRID PLATFORM FOR THE SUSTAINABLE RECOVERY OF ULTRA-PURE RARE EARTH ELEMENTS FROM COMPLEX WASTE STREAMS. ADVANCED MEDICINE

COMPANY DETAILS LOCATION Quakenbrück, Germany

ESTABLISHED YES

TRL TRL 3

EMPLOYEES 10

FUNDING DETAILS FUNDING STAGE PRE-SEED

FUNDING NEEDED 4,000,000 EUR

36

WEBSITE www.bioweg.com

BIOPELEACH is building a biohybrid platform that uses fermentation-derived bioacids from industrial side streams to release rare earths from waste, then highly selective peptides to capture individual elements. This enables cleaner, more circular recovery with far lower chemical use than conventional hydrometallurgy.

COMPUTA

Our mission is to use biology to solve the rare earth challenge by recovering valuable elements from waste and turning them into a circular, domestic source of critical raw materials.

VITALA

APPROACH

STATUS BIOPELEACH has shown bio-based leaching of rare earths and selective peptide-based capture, validating targeted recovery from complex waste. Current work improves selectivity, robustness, and process integration. With BIOWEG and TU Berlin, the technology is advancing toward pilot-scale use with real industrial waste streams.

ALGORA

MATERIA

MOTIVATION

Ana Pérez-López

FACTURA

Adam Belsom

STELLA

Prateek Mahalwar

ENERGIA

TEAM

37

BIOTX.AI MAPPING HOW GENES CAUSALLY SHAPE BIOLOGY. ADVANCED MEDICINE

COMPANY DETAILS LOCATION Potsdam, Germany

ESTABLISHED YES

WEBSITE www.biotx.ai

TRL TRL 8

FUNDING DETAILS FUNDING STAGE SERIES A

REVENUE %45,000 EUR

PRIVATE FUNDING - EU 1,000,000 EUR

PUBLIC FUNDING 1,000,000 EUR

38

PRIVATE FUNDING 1,000,000 EUR

By testing every gene across all human tissues using large-scale Mendelian randomization across thousands of diseases and biomarkers, we generate billions of causal data points linking genes to biological outcomes. Our causally annotated data — and the AI models trained on it — create a holistic map that deepens our understanding of human biology.

COMPUTA

Our vision is to disrupt the high-risk biotech business model through a more predictable, data-driven approach. Through causal mapping of the genome, we elucidate disease biology and enable robust prediction of clinical trial success — paving the way for a new era in therapeutics.

VITALA

APPROACH

STATUS Since launching our technology in late 2022, biotx.ai has been developing its own drug candidates while also partnering with biotech and pharmaceutical companies to optimize clinical development - receiving upfront payments, milestone-based compensation, and royalty agreements in return.

ALGORA

MATERIA

MOTIVATION

Roman Fudim

FACTURA

Charles Ravarani

STELLA

Marco Schmidt

ENERGIA

TEAM

39

BRAINQR THERAPEUTICS BRAINQR DEVELOPS NEXT-GENERATION THERAPIES FOR MAJOR HUMAN DISEASES BY TARGETING DISORDERED PROTEINS. ADVANCED MEDICINE

COMPANY DETAILS LOCATION Göttingen, Germany

ESTABLISHED YES

TRL TRL 4

EMPLOYEES 5

WEBSITE www.brainqrtherapeutics.com

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED 1,300,000 EUR

PUBLIC FUNDING 3,0%0,000 EUR

40

PRIVATE FUNDING - EU &,%50,000 EUR

brainQr develops oral small-molecule drugs that stabilize Tau, the key driver of cognitive decline in Alzheimer’s.

Using its proprietary AI-IDP platform brainQr targets previously undruggable disordered proteins to enable disease-modifying therapies.

COMPUTA

brainQr addresses the lack of disease-modifying therapies for Alzheimer’s, affecting over 40 million people worldwide. By stabilizing Tau, the key driver of cognitive decline, brainQr aims to preserve cognition and transform Alzheimer treatment.

VITALA

APPROACH

MATERIA

MOTIVATION

STATUS

ALGORA

brainQr achieved robust preclinical proof-of-concept for its development candidate BQ-141, showing ~47% reduction of Tau propagation and translational biomarker effects. IND-enabling studies will start in Q2 2026.

TEAM

FACTURA

ENERGIA

Lisa Marie Ramirez

STELLA

Markus Zweckstetter

41

CELLBRICKS FUNCTIONAL TISSUE IMPLANTS - 3D BIOPRINTING OF HUMAN TISSUE FOR REGENERATIVE MEDICINE AND ORGAN REPLACEMENT. ADVANCED MEDICINE

COMPANY DETAILS LOCATION Berlin, Germany

ESTABLISHED YES

TRL TRL 5

EMPLOYEES 27

WEBSITE www.cellbricks.com

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED 50,000,000 EUR

REVENUE 1&-,000 EUR

PRIVATE FUNDING 1,000,000 EUR

PRIVATE FUNDING - EU 7,-00,000 EUR

PUBLIC FUNDING &,&-5,000 EUR

42

A light-based 3D-bioprinting platform combining patient-derived cells with dedicated biomaterials to biofabricate vascularizable human tissue implants. The approach enables controlled architecture, scalability, and integration, supporting functional tissue restoration and organ replacement based on stem cells.

COMPUTA

Millions of patients suffer from tissue loss or organ failure, with limited treatment options and donor shortages. Restoring functional human tissue addresses urgent medical needs today and builds the foundation for scalable organ replacement.

VITALA

APPROACH

STATUS Biofabricated soft tissue implants have shown strong biocompatibility and integration in preclinical studies. Ongoing work focuses on large-animal validation, process scale-up, and translational development, supported by recent funding and growing partnerships with large pharmaceutical companies. Next steps will be Series A for clinical validation.

ALGORA

MATERIA

MOTIVATION

Tobias Lam

FACTURA

Simon MacKenzie

STELLA

Alexander Leutner

ENERGIA

TEAM

43

CINGULUSBIO CINGULUSBIO CAN MAKE DIAGNOSTIC AGENTS WITH HIGH SPECIFICITY FOR ANY TARGET PROTEIN FROM NOTHING BUT THE TARGET‘S SEQUENCE, ULTIMATELY IN LESS THAN & WEEKS AND IN A HIGHLY PARALLEL FASHION. ADVANCED MEDICINE

COMPANY DETAILS LOCATION Zurich, Switzerland

ESTABLISHED NO

TRL TRL 6

PATENTS GRANTED 4

FUNDING DETAILS FUNDING NEEDED 10,000,000 EUR

44

WEBSITE www.cingulusbio.com

Binding proteins are assembled in silico from pre-validated modular building blocks, reducing timelines from months to days while lowering costs and eliminating experimental failure risk. In contrast to full de novo design, precise knowledge on the 3D structure of the target is not required. No target protein is needed, only its sequence.

COMPUTA

By providing fast, inexpensive, and scalable binding reagents for any protein, the company is building a foundational layer of the protein analysis ecosystem. This positions the business for broad adoption, recurring revenue, and strong strategic value as protein measurement becomes as routine and scalable as DNA sequencing.

VITALA

APPROACH

STATUS After 7 mio € public funding, reagents have been created and extensively characterized for a number of typical applications, with very convincing results. Various antibody companies have shown great interest in collaborations. The technology has been extensively patented. Several VCs have shown concrete interest to be part of a syndicate.

ALGORA

MATERIA

MOTIVATION

Anna Hine

Erich Michel

FACTURA

Birte Höcker

STELLA

Andreas Plückthun

ENERGIA

TEAM

45

CONNCONS CONNECTED CONSUMABLES ENABLES IOMT IN MEDICAL CARE. OUR SMART INFUSION SYSTEM IMPROVES CANCER THERAPY SAFETY, SPEEDS TREATMENT BY &0%, AND CUTS MANUAL NURSING TIME BY 50%.

ADVANCED MEDICINE

COMPANY DETAILS LOCATION Dresden, Germany

ESTABLISHED YES

WEBSITE www.conncons.com

TRL TRL 2

PATENTS GRANTED 1

EMPLOYEES 25

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED 300,000 EUR

PRIVATE FUNDING - EU 3,&00,000 EUR

PUBLIC FUNDING 4,000,000 EUR

46

REVENUE &00,000 EUR

Connected Consumables digitally traces medication IDs with integrated chips and the proprietary „Ethernet of Medical Tubing“. The first-in-class multi-input pump automates sequential infusions according to the digital treatment plan. This automation returns valuable time to nurses for patient interaction and clinical decision-making.

• •

CE-certified oncology planning software launched Automated workflow validated with over 50 U.S. nurses, incl. staff from Mayo Clinic Feasibility of ID-check through inductive coupling of connected consumables FDA presubmission confirming 510(k) pathway with no clinical trial required

ALGORA

STATUS • •

COMPUTA

Already today, patients face delayed start of cancer treatment due to staff shortages. The rising number of cancer cases further endanger access to care. The workflow has not changed in decades: Nurses manually checking medications in 4-eyes principle, calculate dose-rates and operating clamps to switch multiple sequential infusion steps.

VITALA

APPROACH

MATERIA

MOTIVATION

Jochen Hampe

Jesse Ambrosia

FACTURA

Marika Geißler

STELLA

Nora Herzog

ENERGIA

TEAM

47

CPTX CPTX PIONEERS IN VIVO CAR-T THERAPIES USING SINGLE-STRANDED DNA TO PROGRAM IMMUNE CELLS DIRECTLY IN THE BODY, ENABLING SAFER AND SCALABLE GENETIC MEDICINES FOR ONCOLOGY, AUTOIMMUNE DISEASES AND BEYOND. ADVANCED MEDICINE

COMPANY DETAILS LOCATION Munich, Germany

ESTABLISHED YES

WEBSITE www.cptx.bio

TRL TRL 6

PATENTS GRANTED 15

EMPLOYEES 30

FUNDING DETAILS FUNDING STAGE SERIES A

PRIVATE FUNDING 15,000,000 EUR

PUBLIC FUNDING 13,000,000 EUR

48

PRIVATE FUNDING - EU &5,000,000 EUR

CPTx combines proprietary immune-quiet single-stranded DNA with targeted lipid nanoparticle (tLNP) delivery to enable in vivo genetic programming of immune cells. This platform supports precise gene expression, improved tolerability, and the potential for repeat dosing, while avoiding the complexity of viral vectors and ex vivo cell manufacturing.

COMPUTA

CPTx develops a new generation of genetic medicines that can be delivered directly to patients without complex manufacturing. By simplifying how cell therapies are produced and delivered, we seek to make powerful genetic treatments more scalable and accessible across oncology, autoimmune diseases, and beyond.

VITALA

APPROACH

STATUS CPTx is advancing preclinical development of its ssDNA-tLNP platform and lead in vivo CAR-T programs. Current work focuses on vector and delivery optimization, lead candidate selection, and IND-enabling studies. The first program targets relapsed or refractory diffuse large B-cell lymphoma (R/R DLBCL) with a dual CD19/CD20 in vivo CAR-T therapy.

ALGORA

MATERIA

MOTIVATION

TEAM

FACTURA

ENERGIA

Christian Sigl

STELLA

Hendrik Dietz

49

DENAZYME DENAZYME THERAPEUTICS REVOLUTIONIZES CANCER THERAPY WITH DNA-POWERED PRECISION. ADVANCED MEDICINE

COMPANY DETAILS LOCATION Duesseldorf, Germany

ESTABLISHED NO

EMPLOYEES 12

TRL TRL 3

FUNDING DETAILS FUNDING STAGE PRE-SEED

FUNDING NEEDED 1&,000,000 EUR

50

PUBLIC FUNDING 4,000,000 EUR

Our technology is based on the extraordinary advantages of high-precision DNA enzymes.

Our key advancement is the development of a new mechanistic understanding that allows us to design a modular platform to overcome current obstacles. Proof-of-principle and further development pipeline have been established.

COMPUTA

Our vision is to fundamentally transform drug discovery through modular, sustainable and affordable high-precision DNA enzymes.

VITALA

APPROACH

STATUS We have developed a next generation DNAzyme platform that shows strong therapeutic effects in vitro, in cello and in vivo. We filed multiple patent applications covering different aspects of our platform. Considerable public funding and a strong (non-academic) network allow the current development of lead candidate and targeted delivery.

ALGORA

MATERIA

MOTIVATION

Philipp Lang

FACTURA

Hannah Rosenbach

STELLA

Manuel Etzkorn

ENERGIA

TEAM

51

INCEPHALO THERAPEUTICS INCEPHALO UNLOCKS THE NEXTGENERATION OF THERAPIES FOR THE CENTRAL NERVOUS SYSTEM, ENABLING LOCALIZED, SAFE AND EFFECTIVE TREATMENTS FOR PATIENTS SUFFERING FROM BRAIN TUMORS. ADVANCED MEDICINE

COMPANY DETAILS LOCATION Zurich, Switzerland

ESTABLISHED YES

WEBSITE www.incephalo.com

TRL TRL 7

PATENTS GRANTED 2

EMPLOYEES 5

FUNDING DETAILS FUNDING STAGE SEED

PRIVATE FUNDING - EU 4,500,000 EUR

52

PUBLIC FUNDING 4,000,000 EUR

InCephalo’s proprietary Compartment Lock technology enables the local administration of tailor-made biological drugs directly into the brain or cerebrospinal fluid, retaining them behind the blood-brain barrier in CNS tissue while ensuring rapid systemic degradation if leakage occurs. This dual mechanism creates a wide therapeutic window.

COMPUTA

Brain cancer remains one of the deadliest and least curable forms of cancer, yet it continues to suffer from a scarcity of investment and innovation. To lower the barriers to investing in this high-need field, we developed a versatile platform technology designed to target brain tumors and to hold curative potential for other neurological diseases.

VITALA

APPROACH

STATUS The first preclinical asset, InC01 (C-Locked IL-12) , and proof of concept has achieved significant de-risking and is 18 months away from the clinic. We demonstrated superior efficacy in animal models of glioblastoma and ex vivo human brain tumor tissue, with robust immune activation and tumor regression while maintaining a wide therapeutic window.

ALGORA

MATERIA

MOTIVATION

TEAM

FACTURA

ENERGIA

Johannes vom Berg

STELLA

Carlo Bertozzi

53

INGINEEON INGINEEON DEVELOPS CYTOKINE-BASED IMMUNOTHERAPEUTICS TO MAKE TODAYS UNTREATABLE DISEASES TREATABLE. ADVANCED MEDICINE

COMPANY DETAILS LOCATION Martinsried, Germany

ESTABLISHED YES

WEBSITE www.ingineeon.com

TRL TRL 5

PATENTS GRANTED 2

EMPLOYEES 5

FUNDING DETAILS FUNDING STAGE PRE-SEED

FUNDING NEEDED &0,000,000 EUR

54

Impaired immunity is a major disease driver in systemic inflammations like sepsis but also cancer. We have developed the worldwide first human interleukin-27alpha-based immunotherapeutic (INGp-010X). INGp-010X is a first-in-class biopharmaceutical with a novel Mechanism of Action for precise restoration of immune competence.

COMPUTA

Active Immunomodulation is of the most promising approaches in modern precision medicine. To bring this to the next level, we at ingineeon develop first-in-class cytokine-based immunotherapeutics. Our therapeutics have breakthrough potential to address todays biggest unmet medical needs in infectious diseases, immuno-oncology and autoimmunity.

VITALA

APPROACH

STATUS Building on in vivo animal and ex vivo human Proof of Concept studies in patients in several indications, INGp-010X is only few milestones away from entry into the clinics. The regulatory authority provided positive opinion on the therapeutic breakthrough potential as well as accelerated market access for the INGp-010X program.

ALGORA

MATERIA

MOTIVATION

Daniel Horn-Ghetko

Isabel Aschenbrenner

FACTURA

Matthias Feige

STELLA

Julia Behnke

ENERGIA

TEAM

55

KANO THERAPEUTICS TARGETED CORRECTION OF GENE-LENGTH STRETCHES OF DNA THROUGH A NEW CLASS OF BIOMATERIAL0 CIRCULAR SINGLE-STRANDED DNA. ADVANCED MEDICINE

COMPANY DETAILS LOCATION Cambridge, England

ESTABLISHED YES

TRL TRL 6

EMPLOYEES 6

FUNDING DETAILS FUNDING STAGE SEED

REVENUE 50,077 EUR

56

WEBSITE

www.kanotherapeutics.com

Lack of DNA payload innovation is a fundamental industry bottleneck that limits which therapies can reach patients. Kano is committed to perfecting the genetic payload itself. Our circular single-stranded DNA (cssDNA) functions as a versatile building block, working across delivery modalities and therapeutic approaches.

COMPUTA

We envision a future where medicines act at the most fundamental level of disease. By improving the DNA instructions inside cells, new therapies can address root causes instead of symptoms, opening the door to cures for severe genetic disorders, cancer, and other conditions where patients today have few or no options.

VITALA

APPROACH

MATERIA

MOTIVATION

STATUS

ALGORA

Kano‘s DNA platform is being evaluated in six drug development programs with goal to reach first patients by 2028. We have shipped KanoDNA to clients tackling various cancers, auto-immune diseases, and severe genetic disorders.

TEAM

STELLA

FACTURA

ENERGIA

Floris Engelhardt

57

LIMAA LIMAA BUILDS THE FIRST FULLY AUTOMATED, TISSUE-PRESERVING HISTOLOGY PLATFORM FOR CLINICAL APPLICATION. ADVANCED MEDICINE

COMPANY DETAILS LOCATION Berlin, Germany

ESTABLISHED YES

WEBSITE

TRL TRL 5

PATENTS GRANTED 1

EMPLOYEES 15

www.limaa-technologies.com

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED 15,000,000 EUR

PRIVATE FUNDING - EU 3,%&0,000 EUR

PUBLIC FUNDING 1,540,000 EUR

58

REVENUE 10&,340 EUR

LIMAA integrates light sheet imaging, nanobody labeling, lab automation and software into a unified platform for tissue scale data generation. The system connects directly to laboratory instruments and pathology LIMS, enabling automated preparation and analysis of entire tissue samples to accelerate diagnostics and improve clinical decision making.

COMPUTA

LIMAA is building the category-leading automated physical infrastructure for sample handling and volumetric tissue imaging in clinical pathology.

The platform generates standardized tissue datasets while preserving samples for genomics, helping labs manage rising case volumes and enabling AI-driven diagnostics.

VITALA

APPROACH

STATUS Team of 16 experts; automated volumetric H&E staining sample handling (category-defining); >50 biomarker pipeline; strong in-house development & regulatory expertise; pilot customer + 3 additional pilot LOIs; LIMAApath software in development; TSO500 Illumina integrated; fits standard histology workflows; ISO 13485 planned for end-2026.

ALGORA

MATERIA

MOTIVATION

TEAM

FACTURA

ENERGIA

Mélanie Guenter

STELLA

Fabian Mohr

59

METAIMMUNE THERAPEUTICS METAIMMUNE IS DEVELOPING NOVEL MEDICINES THAT PRECISELY MODULATE IMMUNE METABOLISM TO PROVIDE MORE EFFECTIVE AND TOLERABLE TREATMENTS FOR INFLAMMATION AND AUTOIMMUNE DISEASES. ADVANCED MEDICINE

COMPANY DETAILS LOCATION Berlin, Germany

ESTABLISHED YES

TRL TRL 2

PATENTS GRANTED 1

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED 6,000,000 EUR

60

EMPLOYEES 6

One program targets interferonopathies. Our founder discovered a novel metabolite with broader efficacy than current treatments.

Our second program focuses on the anti-inflammatory MoA of glucocorticoids. Our founders discovered a new and druggable pathway that allows for powerful ant-inflammatory agents without the side effects of GCs.

COMPUTA

Based on groundbreaking discoveries of our renowned co-founders we develop breakthrough small molecules through metabolic reprogramming of immune function to treat inflammatory disease. Inflammatory diseases affect over 230M people worldwide.

Developing more efficacious / safer treatments will greatly benefit patients worldwide.

VITALA

APPROACH

STATUS MetaImmune is seeking a seed round of € 6M to advance the two programs to the lead optimization and hit-to-lead stage.

Starting operations at CLIC co-lab in Berlin with initial funding from Sprind.

Founding management comprised of successful drug hunters and entrepreneurs with extensive company building expertise and proven track record.

ALGORA

MATERIA

MOTIVATION

Gerhard Krönke

FACTURA

Eicke Latz

STELLA

Maja Kraas

ENERGIA

TEAM

61

PANOSOME A NOVEL FUSOGENIC NANOPARTICLE FOR THE DELIVERY OF GENE THERAPY CARGO. ADVANCED MEDICINE

COMPANY DETAILS LOCATION Heidelberg, Germany

ESTABLISHED YES

WEBSITE www.panosome.com

TRL TRL 4

PATENTS GRANTED 1

EMPLOYEES 13

FUNDING DETAILS FUNDING STAGE PRE-SEED

FUNDING NEEDED %,000,000 EUR

62

PUBLIC FUNDING 500,000 EUR

Naturally produced extracellular vesicles from Trypanosome parasites are membrane fusogenic (delivering cargo directly to the cytoplasm), yet lack immunogenicity. Panosome harnessed this property to create nanoVAST, a semi-synthetic delivery particle, and used a sortase-assisted method of attaching cell-specific targeting elements to the particle.

COMPUTA

There are more than 230 CRISPR gene therapy trials currently ongoing but a dearth of delivery modalities (AAV, LNP) most of which have specific problems (e.g immunogenicity, endosome trapping, poor tissue tropism, liver accumulation). There is an urgent need to develop delivery vehicles that address these limitations. nanoVAST fullfils that need.

VITALA

APPROACH

STATUS We have developed a robust GMP-like production process. The particles efficiently deliver cargo to a multitude of cell types and are uniquely ideal for transporting RNA editing guide RNAs. The aim is to validate the technology in vivo and then spin it out into a NewCo focused on one specific therapeutic indication – neoepitope formation in cancer.

ALGORA

MATERIA

MOTIVATION

FACTURA

Joey Verdi

STELLA

Nina Papavasiliou

ENERGIA

TEAM

63

PRINNOVATION PRINNOVATION‘S GOAL IS THE CLINICAL DEVELOPMENT OF A DRUG CANDIDATE AGAINST ALZHEIMER’S DISEASE WITH AN INNOVATIVE MODE OF ACTION. ADVANCED MEDICINE

COMPANY DETAILS LOCATION Leipzig, Germany

ESTABLISHED YES

WEBSITE www.www.primus-ad.com

TRL TRL 7

PATENTS GRANTED 2

EMPLOYEES 11

FUNDING DETAILS FUNDING STAGE PRE-SEED

PRIVATE FUNDING - EU 15,000,000 EUR

64

PUBLIC FUNDING &,500,000 EUR

Conduct of a Phase II clinical trial to demonstrate safety and efficacy of our drug candidate PRI-002 against the Alzheimer Disease. Compliance with regulatory pathway for clinical development. EMA-approval for the conduct of the PRImus-AD phase II clinical trial was received in November 2023.

COMPUTA

Successful outcome of Phase II clinical trial. Continuous clinical development in a phase III clinical trial to archive market approval. Making PRI-002 available for patients.

VITALA

APPROACH

MATERIA

MOTIVATION

STATUS

ALGORA

The PRImus-AD clinical phase II trial will be closed and analysed this year.

Dieter Willbold

Philipp Bürling

FACTURA

Alexander Brener

STELLA

Kathrin Zeiger

ENERGIA

TEAM

65

SNIPR BIOME SNIPR INTENDS TO RADICALLY DISRUPT AND IMPROVE TREATMENTS BRINGING CRISPR MEDICINES TO MILLIONS OF PEOPLE AT LOW COST. ADVANCED MEDICINE

COMPANY DETAILS LOCATION Copenhagen, Denmark

ESTABLISHED YES

WEBSITE www.sniprbiome.com

TRL TRL 6

PATENTS GRANTED 60

EMPLOYEES 40

FUNDING DETAILS FUNDING STAGE SERIES B

FUNDING NEEDED 15,000,000 EUR

PUBLIC FUNDING 11,000,000 EUR

66

PRIVATE FUNDING - EU 50,000,000 EUR

SNIPR is developing CRISPR-based precision medicines that we program to target any AMR bacterium of our choice. Our CRISPR technology is loaded onto bacterial viruses (phages) or good bacteria to deliver the CRISPR payload. In the target cell, CRISPR precisely cuts the DNA and kills the cell, leaving the healthy bacteria in the microbiome intact.

COMPUTA

The antimicrobial resistance (AMR) pandemic is affecting millions of people globally, including countries in EU with human suffering and high monetary costs as a consequence. Despite the growing need, new antimicrobial therapies are becoming rare. SNIPR is developing novel classes of CRISPR based anti-AMR precision medicines.

VITALA

APPROACH

STATUS SNIPR currently has 4 programs targeting major bacterial pathogens. Our most advanced asset, SNIPR001, is designed to kill AMR E. coli in the gut to prevent blood stream infections in vulnerable cancer patients. We seek funding to extend our ongoing phase 2 clinical trial with SNIPR001 and to further apply our technology to emerging AMR treats.

ALGORA

MATERIA

MOTIVATION

Eric van der Helm

FACTURA

Jakob Haaber

STELLA

Christian Groendahl

ENERGIA

TEAM

67

SURFACTOBIOTECH SURFACTOBIOTECH OFFERS A DROPLET PLATFORM TECHNOLOGY THAT SIGNIFICANTLY INCREASES THE EFFICIENCY OF BIOTECHNOLOGICAL WORKFLOWS. ADVANCED MEDICINE

COMPANY DETAILS LOCATION Hamburg, Germany

ESTABLISHED YES

WEBSITE www.surfactobio.tech

TRL TRL 5

PATENTS GRANTED 1

EMPLOYEES 5

FUNDING DETAILS FUNDING STAGE PRE-SEED

FUNDING NEEDED 5,000,000 EUR

PUBLIC FUNDING 150,000 EUR

68

PRIVATE FUNDING - EU 1&0,000 EUR

Our modular SURFACES platform is designed with swappable layers: excitation (lasers), detection (optical), processing (cartridges), analysis (AI algorithms) that delivers 10+ assays on one instrument. We monetize via instruments (€160K-€1M), consumables (>70% margin), and software subscriptions to drive our recurring revenue and capital efficiency.

COMPUTA

We revolutionize lab testing by replacing costly, slow methods with precision droplet experimentation.

Our SURFACES platform, validated in protein crystallography, now pivots to clinical labs to deliver faster, cheaper, and higher confidence breast cancer ctDNA and HPV tests. European patients and health systems gain diagnostic sovereignty today.

VITALA

APPROACH

STATUS €970k raised (grants + equity); HALRIC pilot active; 1 patent cleared international evaluation and 1 patent in the pipeline; instrument modularity documented; LOI‘s and MoU‘s signed by >5 partners; SLUSH100 finalist as well as pitch awards and invited keynotes; collaboration contract with Thermo Fisher Scientific

ALGORA

MATERIA

MOTIVATION

TEAM

STELLA

FACTURA

ENERGIA

Jacqueline De Lora

69

SYDRA AI-ASSISTED, PHENOTYPE-FIRST DRUG DISCOVERY0 SYDRA FINDS NOVEL MOLECULES, VALIDATES THEM IN VIVO, THEN MAPS TARGETS1MOA - DELIVERING DE-RISKED THERAPEUTICS FOR AGE-ASSOCIATED DISEASES. ADVANCED MEDICINE

COMPANY DETAILS LOCATION

Hombrechtikon, Switzerland

ESTABLISHED YES

WEBSITE www.sydra.bio

TRL TRL 4

PATENTS GRANTED 2

EMPLOYEES 2

FUNDING DETAILS FUNDING STAGE PRE-SEED

FUNDING NEEDED &,%50,000 EUR

PRIVATE FUNDING - EU 107,000 EUR

PUBLIC FUNDING 135,000 EUR

70

PRIVATE FUNDING %&,000 EUR

SYDRA uses an AI-assisted, phenotype-first “Hit-to-Target” workflow: we generate/prioritize small molecules, validate their effects in vivo (C. elegans and elderly rodents), and only then identify targets and mechanisms. This reduces translation risk and builds partner-ready drug candidates for age-associated diseases.

COMPUTA

Aging is the main risk factor behind most chronic diseases, yet medicine still treats late-stage symptoms one by one. SYDRA aims to change this by discovering geroprotective molecules that target aging biology itself, helping people stay healthier for longer and reducing the burden on patients, families, and healthcare systems.

VITALA

APPROACH

STATUS SYDRA has shown proof of concept: 5 novel, AI-discovered geroprotectors validated in C. elegans, with 2 lead candidates extending lifespan and improving healthspan in elderly mice. Both now move into target/MoA deconvolution to nominate disease indications. A pre-alpha generative AI model for novel chemicals is also ready.

ALGORA

MATERIA

MOTIVATION

TEAM

FACTURA

ENERGIA

Pavlo Mozharovskyi

STELLA

Alexander Dakhovnik

71

SYMBIOTICA THERAPEUTICS SYMBIOTICA THERAPEUTICS DEVELOPS A PATENTED PLATFORM USING LIVING MICROALGAE THAT, AFTER CUTANEOUS INJECTION, CONTINUOUSLY RELEASE THERAPEUTIC PROTEINS. ADVANCED MEDICINE

COMPANY DETAILS LOCATION Pisa, Italy

ESTABLISHED YES

TRL TRL 4

EMPLOYEES 5

WEBSITE www.symbioticatherapeutics.org

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED 1,500,000 EUR

72

REVENUE 70,000 EUR

We use engineered micro-algae injected cutaneously that remain at injection site while continuously secreting proteins into bloodstream.

SPRIND supports current non-GLP in vivo efficacy rodent studies, we then plan GLP-toxicology and PK studies for IND.

COMPUTA

Many treatments for chronic diseases require repeated doses or invasive systems, increasing risk, cost, and poor patient compliance. We aim to transform chronic diseases therapies using a safer, cheaper, sustained and more effective platform we developed

VITALA

APPROACH

STATUS National patent for symbiotic platform filed in 2025, PCT coming in 2026. We showed early in-vivo proof-of-concept and safety. IND-oriented non-GLP rodent efficacy study ongoing and currently funded by SPRIND. Other national public grants secured 2025

ALGORA

MATERIA

MOTIVATION

Barbora Porubová

FACTURA

Francesco Morabito

STELLA

Gabriele Morabito

ENERGIA

TEAM

73

TQ THERAPEUTICS DELIVERING UNPRECEDENTED SAFE IN VIVO CELL THERAPIES THROUGH PRECISION TARGETING, MAKING CHALLENGING DISEASES CURABLE FOR EVERYONE. ADVANCED MEDICINE

COMPANY DETAILS LOCATION Planegg, Germany

ESTABLISHED YES

TRL TRL 3

EMPLOYEES 12

WEBSITE www.tqtherapeutics.com

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED 30,000,000 EUR

PRIVATE FUNDING - EU 6,000,000 EUR

PUBLIC FUNDING 1,000,000 EUR

74

PRIVATE FUNDING &,000,000 EUR

TQx‘s proprietary EXiVO approach is a hybrid concept combining the control benefits of ex vivo cell processing with the scalability of in vivo therapy.

This enables the CELLfinity platform for modular generation of infinite CGT clinical programs for accessible autologous mRNA T-cell therapeutics across indications.

• •

Fresenius as MedTech partner for cell selection development BMS as investor/sponsor target Through acquiring of Juno GmbH, TQ secured robust in vivo process & cell-selection IP PEI regulatory support for the ultra-short in vivo approach Promising mouse proof-of-concept data showing transfection of unactivated cells

ALGORA

STATUS • • •

COMPUTA

TQ Therapeutics develops a hybrid in vivo CAR-T platform enabling ultrafast 6-hour cell therapy processing at the patients‘ point-of-care.

VITALA

APPROACH

MATERIA

MOTIVATION

Christian Stemberger

Christin Zündorf

FACTURA

Sabine Radisch

STELLA

Christian Eckert

ENERGIA

TEAM

75

TRANSMUTEX TRANSMUTEX DEVELOPS AN ACCELERATOR-DRIVEN SYSTEM TO PRODUCE RADIOISOTOPES FOR CANCER MEDICATION (TARGETED ALPHA THERAPY, E.G. AC&&5 AND PB&1&, FOR &00,000 PATIENTS PER YEAR. ADVANCED MEDICINE

COMPANY DETAILS LOCATION Geneva, Switzerland

ESTABLISHED YES

WEBSITE www.transmutex.com

TRL TRL 5

PATENTS GRANTED 10

EMPLOYEES 62

FUNDING DETAILS FUNDING STAGE SERIES B

FUNDING NEEDED 100,000,000 EUR

REVENUE &00,000 EUR

PRIVATE FUNDING &&,000,000 EUR

PRIVATE FUNDING - EU 1%,000,000 EUR

PUBLIC FUNDING 10,000,000 EUR

76

Transmutex develops a high-performance proton accelerator to produce radioisotopes such as Actinium-225, Lead-212 and the Terbium sisters that are currently the most promising candidates in clinical trials for targeted alpha therapy.

COMPUTA

Transmutex aims to revolutionize nuclear medicine by producing radioisotopes for cancer medication (theranostics) at a previously unknown scale and costs.

VITALA

APPROACH

MATERIA

MOTIVATION

STATUS

ALGORA

All major players (research institutes, pharma companies, suppliers, operators) have confirmed that they either want to collaborate with us or recognize the superiority of our approach.

Craig Kelly

Donovan Maire

FACTURA

Guido Houben

STELLA

Franklin Servan-Schreiber

ENERGIA

TEAM

77

ULTRABRIGHT BIOTECH TURN TODAY’S MEDICAL TESTS INTO ULTRA-EARLY DISEASE DETECTORS. ADVANCED MEDICINE

COMPANY DETAILS LOCATION Munich, Germany

ESTABLISHED YES

TRL TRL 4

PATENTS GRANTED 2

WEBSITE www.ultrabright.bio

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED 4,000,000 EUR

PRIVATE FUNDING - EU 100,000 EUR

PUBLIC FUNDING 1,000,000 EUR

78

REVENUE 150,000 EUR

We make weak signals bright. Our technology turns a single detection event into a super-strong signal—like switching from a candle to a floodlight. It works with today’s tests and machines, making them far more sensitive without changing how labs already operate.

COMPUTA

Most diseases are detected too late because current tests lack sensitivity.

Ultrabright enables orders-of-magnitude earlier detection—before symptoms appear. Our Ultra-Beacon technology unlocks a new generation of ultra-sensitive diagnostics for clinical labs, point-of-care, and research, transforming how disease is found and managed.

VITALA

APPROACH

STATUS Ultrabright operates an active revenue-generating business that we are now scaling. Our customers include leading global diagnostics and pharmaceutical companies. We have validated strong market demand, established partnerships, and a growing pipeline, positioning us for rapid commercial expansion.

ALGORA

MATERIA

MOTIVATION

Benjamin Kick

FACTURA

Jonas Funke

STELLA

Klaus Wagenbauer

ENERGIA

TEAM

79

UNOMR UNOMR DEVELOPS NANOPORE-BASED TECHNOLOGIES FOR SINGLE-MOLECULE PROTEIN SEQUENCING, OPENING NEW POSSIBILITIES FOR PRECISION MEDICINE, BIOTECHNOLOGY, AND FOOD INNOVATION. ADVANCED MEDICINE

COMPANY DETAILS LOCATION Zurich, Switzerland

ESTABLISHED YES

WEBSITE www.unomr.com

TRL TRL 5

PATENTS GRANTED 1

EMPLOYEES 7

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED %,000,000 EUR

80

PUBLIC FUNDING 1,000,000 EUR

UNOMR uses interface nanopore (iNP) sensors to analyze single protein molecules in solution. By repeatedly re-reading a single protein, complexity decomposition extracts residue-level signals letter by letter.

Each pass capturing partial information that, aggregated across many reads, reconstructs the full sequence and modification landscape.

COMPUTA

UNOMR AG, a techBio startup from ETH Zurich, is developing next-generation protein sensors to solve one of the biggest blind spots in modern biology and medicine: our inability to fully read and understand proteins.

Envisioning single-molecule protein sequencing through their innovative interface nanopore sensor, we currently focus on PTM analysis.

VITALA

APPROACH

STATUS Founded on ETH Zurich doctoral research, UNOMR has filed a PCT patent, secured non-dilutive funding (BRIDGE, Innosuisse, InnoBooster), completed proof-of-concept at TRL 5, closed pre-seed financing, and is now developing an Early Access Device with pilot projects underway at industry partners and worldleading academic labs.

ALGORA

MATERIA

MOTIVATION

Julian Hengsteler

FACTURA

Julia Wagner

STELLA

Til Schlotter

ENERGIA

TEAM

81

VIFERAXS VIFERAXS DEVELOPS IMMUNOPEPTIDOME-BASED CANCER VACCINES THAT ENABLE PRECISE AND DURABLE T-CELL ACTIVATION AGAINST CANCER. ADVANCED MEDICINE

COMPANY DETAILS LOCATION Tübingen, Germany

ESTABLISHED YES

WEBSITE www.viferaxs.com

TRL TRL 7

PATENTS GRANTED 1

EMPLOYEES 4

FUNDING DETAILS FUNDING STAGE SERIES A

FUNDING NEEDED 10,000,000 EUR

82

PRIVATE FUNDING - EU 500,000 EUR

ViferaXS uses an immunopeptidomedriven platform to identify tumor-specific antigens and develop off-the shelf peptide T cell activators combined with the XS15 adjuvant. This approach activates targeted T-cell responses to eliminate cancer cells and prevent disease progression.

COMPUTA

Cancer patients lack effective, well-tolerated therapies that prevent progression or relapse at early stage.

Current treatments are often toxic and non-curative. ViferaXS develops targeted immunotherapies to induce durable anti-tumor immunity and improve outcomes.

VITALA

APPROACH

STATUS First patent secured, with lead programs in AML, FLC, and prostate cancer currently in Phase I. A Phase II-ready CLL program is in place, supported by strong academic collaborations (e.g. Tübingen). Backed by a secured KMUi Biomedizin grant, the company has generated strong pharma interest in CLL and is now seeking funding to initiate Phase II.

ALGORA

MATERIA

MOTIVATION

Hans-Georg Rammensee

FACTURA

Juliane Walz

STELLA

Sezai Taskin

ENERGIA

TEAM

83

AEVOLOOP AEVOLOOP DEVELOPS FULLY RECYCLABLE, MICROPLASTIC-FREE, MULTIPURPOSE PERFORMANCE PLASTICS AT COMPETITIVE PRICING. NEXT-GEN MATERIALS

COMPANY DETAILS LOCATION Leipzig, Germany

ESTABLISHED YES

TRL TRL 5

EMPLOYEES 20

WEBSITE www.aevoloop.com

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED 1,500,000 EUR

REVENUE 10,000 EUR

PRIVATE FUNDING 1,74&,400 EUR

PRIVATE FUNDING - EU &,60%,000 EUR

PUBLIC FUNDING %00,000 EUR

84

We develop polyolefin-like plastics based on long-chain dicarboxylic acids. Their molecular design combines strong material performance with built-in breaking points for chemical recycling, enabling recovery of highquality building blocks under mild conditions for repeated reuse.

COMPUTA

We address a core problem of the plastics industry: today’s materials are high-performing but rarely truly circular. Packaging and other high-volume plastic applications are affected. This matters because the market needs materials that combine performance, circularity, and biodegradability.

VITALA

APPROACH

STATUS Since its founding in 2024, aevoloop has shown early market traction and strong technical progress: about €11.4m secured, TRL 5/6 reached, 20 kg batches validated, drop-in processing on standard equipment demonstrated, and first pilot and scale-up data generated.

ALGORA

MATERIA

MOTIVATION

TEAM

FACTURA

ENERGIA

Manuel Häußler

STELLA

Philipp Keßler

85

AMPHICO AMPHICO IS A DEEP-TECH COMPANY BUILDING MANUFACTURING-READY SYSTEMS FOR PERFORMANCE PROTECTION AND COLOUR WITHOUT HIDDEN TOXIC CHEMISTRIES. NEXT-GEN MATERIALS

COMPANY DETAILS LOCATION London, England

ESTABLISHED YES

WEBSITE www.amphico.uk

TRL TRL 8

PATENTS GRANTED 3

EMPLOYEES 20

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED 5,000,000 EUR

REVENUE 60,000 EUR

PRIVATE FUNDING &,000,000 EUR

PRIVATE FUNDING - EU &60,000 EUR

PUBLIC FUNDING 4,000,000 EUR

86

AMPHICO has developed two proprietary technologies leveraging AI powered manufacturing processes.

AMPHITEX is a PFAS-free waterproof breathable membrane engineered for circularity. AMPHICOLOR delivers waterless colour through weaving, with 3,000+ validated colours and consistent results at full mass manufacturing scale.

COMPUTA

Hidden toxic chemistries are standard across the textile industry.

PFAS ‚forever chemicals‘ dominate performance waterproofing; conventional dyeing consumes vast water and harmful dyes. Both cause lasting damage to ecosystems and human health. AMPHICO exists to remove these chemistries without sacrificing performance or colour.

VITALA

APPROACH

STATUS Multiple Innovate UK grants and SPRIND funding secured with technology now at TRL8, with product deployment planned in Q3-2026 to our clients. Active pilots and LOIs signed including with one of the largest textile distribution company in Japan, the Luxury brands group Kering and multiple outdoor brands and manufacturers.

ALGORA

MATERIA

MOTIVATION

TEAM

FACTURA

ENERGIA

Louise Anderson

STELLA

Jun Kamei

87

AMPHISTAR (SURFACYCLE, AMPHISTAR PRODUCES VARIOUS BIOSURFACTANTS FROM AGRI-FOOD INDUSTRY WASTE. NEXT-GEN MATERIALS

COMPANY DETAILS LOCATION Ghent, Belgium

ESTABLISHED YES

WEBSITE www.amphistar.com

TRL TRL 5

PATENTS GRANTED 4

EMPLOYEES 25

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED &0,000,000 EUR

PRIVATE FUNDING - EU 6,500,000 EUR

PUBLIC FUNDING 1&,000,000 EUR

88

REVENUE 100,000 EUR

Versatile and robust platform technology able to produce over 80 biosurfactants with varying properties.

Developing fully integrated continuous production processes to reduce costs and increase market access.

Integrated approach combining synbio, pretreatment, fermentation and downstream processing. Beachhead markets Home & Personal Care.

COMPUTA

MAKING BIOSURFACTANTS MAINSTREAM! AmphiStar will revolutionize the surfactant industry by making truly sustainable, performant & affordable novel biosurfactants. Produced from WASTE!

VITALA

APPROACH

STATUS First two commercial products on the market, pushing at least two new molecules to market in 2026. Three contracts in place with distributors for Home & Personal Care in EU and US: Caldic, Kensing and Stepan.

REACH 1-10ton dossier filed. Currently producing in industrial scale fermenters and reducing cost by moving to fully continuous processes.

ALGORA

MATERIA

MOTIVATION

Karolien Maes

Wim Allegaert

FACTURA

Bernd Everaert

STELLA

Sophie Roelants

ENERGIA

TEAM

89

BIOPHELION BIO-BASED POLYMERS AND SURFACTANTS POWERED BY NEXTGENERATION PROCESSES. NEXT-GEN MATERIALS

COMPANY DETAILS LOCATION Jena, Germany

ESTABLISHED YES

TRL TRL 5

EMPLOYEES 12

WEBSITE www.biophelion.com

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED &,000,000 EUR

PUBLIC FUNDING &,500,000 EUR

90

PRIVATE FUNDING - EU &,500,000 EUR

Technological resilience at all levels: robust strains deliver consistent product quality despite variable inputs, while robust bioprocesses reduce labor requirements and convert locally available organic feedstocks into valuable surfactant and polymers.

COMPUTA

Facing resource scarcity and fragile supply chains, Europe needs a new production model: regional, decentralized biotechnological manufacturing for a resilient and resource-efficient chemical industry - we are satisfying this demand.

VITALA

APPROACH

STATUS First product entering the market by the end of this year, while two additional products are proceeding in development and application research; in parallel, we secured a JDA for additional markets. With our process established across multiple industrial by-product streams, we are now scaling up production to significantly increase capacity.

ALGORA

MATERIA

MOTIVATION

Frederick Haala

FACTURA

Till Tiso

STELLA

Lars Regestein

ENERGIA

TEAM

91

BIOTREASURE BIOTREASURE IS AN INTEGRATED BIOLOGY AND CHEMISTRY MANUFACTURING PLATFORM FOR BIO-BASED CHEMICALS AT INDUSTRIAL SCALE. DESIGNED TO DELIVER PERFORMANCE, COST-EFFICIENCY AND SCALABILITY FROM DAY ONE. NEXT-GEN MATERIALS

COMPANY DETAILS LOCATION Planegg, Germany

ESTABLISHED YES

WEBSITE www.biotreasure.com

TRL TRL 6

PATENTS GRANTED 1

EMPLOYEES 5-10

FUNDING DETAILS FUNDING STAGE PRE-SEED

FUNDING NEEDED 4,000,000 EUR

92

PUBLIC FUNDING &,500,000 EUR

BioTreasure combines continuous fermentation with proprietary downstream chemistry to convert abundant local agricultural and forestry side streams into a broad variety of highperformance bio-based chemicals.

The integrated platform enables efficient, scalable, decentralized production for markets incl. materials, personal care, and agrochemicals.

COMPUTA

Today’s chemical industry depends on carbon-intensive and increasingly fragile petrochemical supply chains.

BioTreasure aims to enable a new generation of decentralized, sustainable manufacturing systems that locally produce high-performance chemicals from renewable resources, strengthening supply resilience while reducing environmental impact.

VITALA

APPROACH

STATUS BioTreasure successfully reached all three stages of SPRIND’s Circular Biomanufacturing Challenge, leading to its incorporation as a venture. The team demonstrated key technical milestones and prototype systems and is now advancing toward industrial-scale implementation and early commercial partnerships.

ALGORA

MATERIA

MOTIVATION

TEAM

FACTURA

ENERGIA

Johannes Sonnenschein

STELLA

Ruchita Chawla

93

BIOXTRACT BIOXTRACT TRANSFORMS COMPLEX WASTE INTO HIGH-VALUE METAL RESOURCES THROUGH PRECISION BIOGEOCHEMISTRY. NEXT-GEN MATERIALS

COMPANY DETAILS LOCATION Nijmegen, Netherlands

ESTABLISHED NO

TRL TRL 3

FUNDING DETAILS FUNDING STAGE PRE-SEED

PUBLIC FUNDING 10,000,000 EUR

94

EMPLOYEES 6

BioXtract targets the recovery of critical metals and rare earth elements (heavy and light) from various waste streams through controlled microbial redox reactions, exploiting natureinspired metal capture mechanisms using minerals and biosorbents, and biogeochemical triggers for selective release of metals from mineral and organic complexes.

COMPUTA

BioXtract envisions a future where the metals powering modern technologies no longer come from mining, but are recovered from the vast resources already present in waste. Our goal is to turn environmental liabilities into sustainable metal supplies, strengthening resource security and enabling a truly circular economy.

VITALA

APPROACH

STATUS BioXtract is an emerging venture that recently secured its first pre-seed funding through the SPRIND Challenge. Our interdisciplinary team of leading experts in biogeochemistry, geomicrobiology, mineralogy, geology, and modelling is validating the technology and preparing the transition from academic research to industrial application.

ALGORA

MATERIA

MOTIVATION

Elizabeth Tomaszewski

Anna Potysz

FACTURA

James Byrne

STELLA

Martyna Glodowska

ENERGIA

TEAM

95

BLUU BLUU CREATES NEXT-GEN BIOACTIVES FROM REAL FISH CELLS USING SCALABLE, GMO-FREE MARINE BIOMANUFACTURING - PROTECTING OCEANS WITH ZERO TRADE-OFFS FOR FOOD, HEALTH, AND PERSONAL CARE. NEXT-GEN MATERIALS

COMPANY DETAILS LOCATION Hamburg, Germany

ESTABLISHED YES

TRL TRL 6

EMPLOYEES 26

WEBSITE www.bluu.bio

FUNDING DETAILS FUNDING STAGE SERIES A

FUNDING NEEDED 17,000,000 EUR

PRIVATE FUNDING - EU &5,000,000 EUR

PUBLIC FUNDING &,460,000 EUR

96

PRIVATE FUNDING &,000,000 EUR

GMO-free cultivation methods are used to develop an immortalised suspension cell line from adult fish stem cells. BLUU‘s production cell lines grow in cell aggregates with controlled size distribution and tailor-made culture media. Depending on the desired product, various downstream processes can be used for food and personal care.

COMPUTA

BLUU was founded with the vision of protecting marine life and preserving marine ecosystems. We invented a proprietary marine biomanufacturing technology delivering complex nextgeneration regenerative bioactives at industrial scale. Created through world-class science - for personal care, health and food. Real fish cells - zero trade offs.

VITALA

APPROACH

STATUS In Hamburg, the first proprietary research and development pilot plant with 50L bioreactors was built at BLUU‘s headquarters in 2023 to optimise the production parameters of the platform technology. Production has already been successfully demonstrated in a 500L and 1000L pilot bioreactor with various partners.

ALGORA

MATERIA

MOTIVATION

Andre Schiefner

Paul Réthy

FACTURA

Stefanie Gromer

STELLA

Sebastian Rakers

ENERGIA

TEAM

97

C3 BIOTECHNOLOGIES C3 BIOTECH TRANSFORMS CHEMICAL PRODUCTION WITH NON-STERILE PLATFORMS – ENABLING COSTEFFICIENT, SCALABLE BIOMANUFACTURING FOR A SUSTAINABLE FUTURE. NEXT-GEN MATERIALS

COMPANY DETAILS LOCATION Manchester, England

ESTABLISHED YES

WEBSITE www.c3biotech.com

TRL TRL 6

PATENTS GRANTED 9

EMPLOYEES 13

FUNDING DETAILS FUNDING STAGE SERIES A

FUNDING NEEDED 5,000,000 EUR

PRIVATE FUNDING - EU 130,000 EUR

PUBLIC FUNDING 14,000,000 EUR

98

PRIVATE FUNDING &10,000 EUR

Demonstrator unit based on SPRIND funded pilot plant studies with game changing technology for non-sterile fermentation. Consistency of robust manufacturing established using wide ranging feedstocks. Achieve minimally 30 tonnes pa production with CoGs equivalent at least to petrochemical prices for commodity chemicals.

COMPUTA

Achieve demonstrator manufacturing with economics that meet petrochemical cost of goods or better. Samples manufactured for offtake. Business expansion for market penetration through JV, licensing or technology sale based on Demonstrator performance and early market penetration.

VITALA

APPROACH

MATERIA

MOTIVATION

STATUS

ALGORA

Pilot plant operations at cost of goods already close to petrochemical parity.

Routes for early market penetration identified and partnerships that introduce C3 materials into everyday goods.

Alexander Agius

FACTURA

Daniele Parisi

STELLA

Nigel Scrutton

ENERGIA

TEAM

99

CELLX BIOSOLUTIONS WE PROVIDE THE FIRST SCALABLE BIOLOGICAL SOLUTION TO DESTROY PFAS IN INDUSTRIAL WASTEWATER, REPLACING COSTLY, CARBON-INTENSIVE INCINERATION WITH A CLEANER AND MORE AFFORDABLE ALTERNATIVE. NEXT-GEN MATERIALS

COMPANY DETAILS LOCATION Zurich, Switzerland

ESTABLISHED YES

TRL TRL 4

EMPLOYEES 6

WEBSITE www.cellx.ch

FUNDING DETAILS FUNDING STAGE PRE-SEED

FUNDING NEEDED 3,%00,000 EUR

100

REVENUE 4%,450 EUR

We use a patent-pending sampling technology to capture rare PFASdegrading bacteria from polluted environments. These strains are optimized and combined into robust consortia, then deployed in contained bioreactors to break down PFAS in industrial wastewater, replacing incineration with a scalable biological destruction process.

COMPUTA

CellX leverages the power of natural bacteria to clean up persistent pollution from water and soils. Our long term vision is to develop a library of bacterial solutions able to degrade all persistent pollutants. As entry market we focus on the „forever chemicals“ PFAS.

VITALA

APPROACH

STATUS We isolated 40+ PFAS-degrading bacterial strains and demonstrated PFAS destruction in lab conditions. Four paid pilots are ongoing with industrial partners.

We secured a € 1.6M preseed funding and € 3M+ grants and reached TRL 4–5, now advancing toward lab-scale bioreactor validation on real industrial effluents.

ALGORA

MATERIA

MOTIVATION

Fabienne Kurt

FACTURA

Geoffrey Besnier

STELLA

Estelle Clerc

ENERGIA

TEAM

101

CMETRE GRENSOL INTRODUCES AN ADVANCED SOLUTION FOR THE COMPREHENSIVE TREATMENT OF PRE-SORTED WASTE PRINTED CIRCUIT BOARDS. NEXT-GEN MATERIALS

COMPANY DETAILS LOCATION Zurich, Switzerland

ESTABLISHED YES

TRL TRL 4

EMPLOYEES 12

WEBSITE www.grensolgroup.com

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED 10,000,000 EUR

PUBLIC FUNDING &,000,000 EUR

102

PRIVATE FUNDING 3,000,000 EUR

Recovering critical metals/raw materials from post-consumer waste, especially materials that would have otherwise been incinerated or landfilled.

Using physical methods to concentrate metal fractions for downstream specialised recycling. Key is to drive efficient separation of waste upfront so targeted processes downstream can recover the materials.

COMPUTA

APPROACH

MATERIA

VITALA

MOTIVATION

STATUS

ALGORA

Operating a physical separation plant for car recycling waste to recover copper, aluminium and steel. Also separating glass for cement making, and plastics for industrial gas production using our patented Photolysis technology.

Marco Ziegler

FACTURA

Marc Ocskay

STELLA

Rajiv Singhal

ENERGIA

TEAM

103

COLIPI COLIPI TRANSFORMS RENEWABLE CARBON THROUGH FERMENTATION INTO SUSTAINABLE PRODUCTS – ENABLING A FUTURE-READY BIOECONOMY AND IMPROVED LIVING CONDITIONS. NEXT-GEN MATERIALS

COMPANY DETAILS LOCATION Hamburg, Germany

ESTABLISHED YES

WEBSITE www.colipi.com

TRL TRL 8

PATENTS GRANTED 3

EMPLOYEES 15

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED 4,500,000 EUR

PRIVATE FUNDING - EU &,000,000 EUR

PUBLIC FUNDING 600,000 EUR

104

REVENUE 500,000 EUR

We ferment renewable carbon (CO2 directly, or indirectly via intermediaries like organic acids or alcohols) with microbes. These microbes are a platform, now producing oils. We applied bioreactor and bioprocess design to enable the fermentation of an explosive gas mixture (H2, O2, CO2). We genetically engineered CO2 consuming bacteria.

Several hundred thousand EURO revenue per year Major deal with L‘Oreal Off-take agreement with one large German cosmetics manufacturer Developed low CAPEX bioprocess, running on plastic IBC containers Developed genetic tools to access a non-standard bacteria Measured world‘s fastest CO2 fixation with our system (highest specific growth rate)

ALGORA

STATUS • • • • • •

COMPUTA

Fermenting Renewable Carbon For Generational Life Quality.

Fossil oil must be phased out. There is not enough land to grow enough vegetable oil to fill the fossil gap. We need a third process of producing oils without adding carbon dioxide to the atmosphere or causing deforestation.

VITALA

APPROACH

MATERIA

MOTIVATION

Philipp Arbter

Tyll Utesch

FACTURA

Jonas Heuer

STELLA

Maximilian Webers

ENERGIA

TEAM

105

DESCYCLE THE DESCYCLE TEAM DEVELOPS A CIRCULAR METALLURGY PLATFORM THAT ENABLES HIGH-EFFICIENCY, LOW-EMISSION RECOVERY OF CRITICAL AND STRATEGIC METALS. NEXT-GEN MATERIALS

COMPANY DETAILS LOCATION London, England

ESTABLISHED YES

EMPLOYEES 16

TRL TRL 7

FUNDING DETAILS FUNDING STAGE SERIES A

FUNDING NEEDED 40,000,000 EUR

PRIVATE FUNDING 15,000,000 EUR

PRIVATE FUNDING - EU 3,500,000 EUR

106

PUBLIC FUNDING -,000,000 EUR

DEScycle uses proprietary ionometallurgy to recover critical metals from electronic waste at low temperature, replacing centralised smelting. The technology enables distributed, modular processing deployed at material sources, shortening value chains and producing traceable, lower-carbon metal supply at scale.

COMPUTA

DEScycle is building the next generation of metals processing infrastructure, replacing centralised smelting with distributed, modular recovery of critical metals from electronic waste.

It matters because Europe’s supply chains are carbon-intensive and exposed to concentrated processing capacity abroad.

VITALA

APPROACH

STATUS Demonstrated >99% target metal recovery in TRL 6 pilot operation and installing a £7m industrial TRL 7 facility. Secured €30m in funding including €10m grants.

Backed by Cisco and Mitsubishi, with a UK JV formed and Japan deployment partnership signed. Active pilot discussions with leading European recyclers and OEMs.

ALGORA

MATERIA

MOTIVATION

Dhivya Puri

Fred White

FACTURA

Leonidas Howden

STELLA

Rob Harris

ENERGIA

TEAM

107

EMPYRIO EMPYRIO DEVELOPS A PATENTED CONTAINERIZED SYSTEM FOR ON-SITE THERMAL UTILIZATION OF SEWAGE SLUDGE AND WET BIOWASTE. NEXT-GEN MATERIALS

COMPANY DETAILS LOCATION Riga, Latvia

ESTABLISHED YES

WEBSITE www.empyrio.com

TRL TRL 7

PATENTS GRANTED 2

EMPLOYEES 6

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED &,500,000 EUR

108

Our technology utilizes 2-step energy-positive process, integrating patented vortex dryer and a rotating bed furnace. This compact, containerized system operates autonomously without external fuel and fits seamlessly into existing infrastructure. It reduces utilization costs by up to 50% while enabling phosphorus recovery from ash.

COMPUTA

Municipalities face rising costs for sludge logistics and disposal, compounded by microplastic and PFAS contamination. Our vision is a decentralized approach, transforming waste into an on-site resource. We aim to set a new standard for sustainable bio-waste processing, protecting soil health and fostering a circular economy.

VITALA

APPROACH

STATUS Currently at TRL 7, we operate an industrial pilot in Latvia. Supported by international patents, EIT InnoEnergy, and Norway Grants, we have finalized the design for our first commercial unit. We are now seeking investment to implement first commercial plant in the sewage sludge market, with plans to scale into broader biowaste sectors.

ALGORA

MATERIA

MOTIVATION

TEAM

STELLA

FACTURA

ENERGIA

Alexander Belskis

109

E-MURGY E-MURGY IS DEVELOPING SCALABLE AND ELECTRIFIED METALLURGICAL PATHWAYS TO SELECTIVELY RECOVER CRITICAL METALS FROM VARIOUS ENDOF-LIFE WASTE STREAMS. BY REGENERATING REAGENTS ELECTROCHEMICALLY WITH RENEWABLE ENERGY. NEXT-GEN MATERIALS

COMPANY DETAILS LOCATION Brussels, Belgium

ESTABLISHED NO

EMPLOYEES 130

TRL TRL 4

FUNDING DETAILS FUNDING STAGE PRE-SEED

FUNDING NEEDED &,500,000 EUR

110

PUBLIC FUNDING 1,&65,000 EUR

E-Murgy is developing scalable and electrified metallurgical pathways to selectively recover critical metals from various end-of-life waste streams. Our modular electrochemical reactors generate multiple redox reagents that are fed into established unit operations, enabling them to create their disruptive approach to ‘decoupled electrometallurgy‘.

COMPUTA

Over the years, improved performance metrics of clean tech devices have come at the cost of using multiple low-volume yet high-value critical metals that are vulnerable to supply restrictions. E-Murgy tackles this complex challenge through the development of disruptive, electrified closed-loop processes that improve selectivity and reduce emissions.

VITALA

APPROACH

STATUS Currently we have developed a platform electrochemical tech that can selectively recover Lithium from end of life black mass and REEs from NdFeB magnet waste using just electricity and water at TRL4. We are testing our process to improve its flexibility and are actively trying to scale it up.

ALGORA

MATERIA

MOTIVATION

Prakash Venkatesan

FACTURA

Héritier Tshipeshi

STELLA

Wing Ching Kwok

ENERGIA

TEAM

111

EVERYCARBON EVERYCARBON PROVIDES HIGH-PERFORMANCE INSULATION FOAMS FROM LOW-COST ORGANIC CARBON WITH NO TRADE-OFFS ON THERMAL STABILITY, STRUCTURAL DURABILITY, OR EMISSIONS. NEXT-GEN MATERIALS

COMPANY DETAILS LOCATION Tuebingen, Germany

ESTABLISHED YES

TRL TRL 4

EMPLOYEES 8

WEBSITE www.everycarbon.bio

FUNDING DETAILS FUNDING STAGE PRE-SEED

FUNDING NEEDED 3,-00,000 EUR

112

PUBLIC FUNDING 6,000,000 EUR

EveryCarbon transforms low-cost organic carbon into high-performance insulation foams using synthetic biology and polymer chemistry. The propriatary technology employs a contiunous fermentation that result in foam that delivers thermal stability and structural durability at competitive cost, with up to 85% lower GHG emissions.

COMPUTA

The built environment relies on insulation materials that force a choice between performance, cost, and sustainability. EveryCarbon enables the next generation of insulation materials for moist and structurally demanding environments. by turning low-cost organic carbon into highperformance polymers.

VITALA

APPROACH

STATUS EveryCarbon is currently in ramping up it‘s pilot operation on-site of a waste-water treatment plant and is validating beachhead applications of it‘s foam material for basement and roofing systems. The company is raising a seed round to advance a scaled CMO production and first commercial partnerships.

ALGORA

MATERIA

MOTIVATION

TEAM

FACTURA

ENERGIA

Apolonio Huerta

STELLA

Sebastian Beblawy

113

FOOM THE FOOM TECHNOLOGY EXTRACTS VALUABLE FERTILIZER FROM ORGANIC WASTE–ON SITE AND IN NO TIME AT ALL0 FEWER EMISSIONS, BETTER SOIL, GREATER BIODIVERSITY. NEXT-GEN MATERIALS

COMPANY DETAILS LOCATION Berlin, Germany

ESTABLISHED YES

TRL TRL 5

EMPLOYEES 3

WEBSITE www.foom.de

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED 1,000,000 EUR

PUBLIC FUNDING 400,000 EUR

114

REVENUE 1&7,-17 EUR

foom converts organic waste into high-quality fertilizer onsite within two days — fully automated and with up to 80% lower CO₂ emissions. The container-based system combines bioengineering, advanced mechanical processing, and IoT-based automation to transform organic waste locally into a resource and enable circular systems for resilient cities.

COMPUTA

Europe still burns or landfills 75% of its organic waste, wasting nutrients and creating significant CO₂ emissions. At the same time, cities must feed growing populations and manage resources sustainably. Unlocking organic waste as a local resource is key to building circular food systems and climate-resilient cities.

VITALA

APPROACH

STATUS foom’s technology has been validated through more than two years of prototyping and is now moving into first commercial deployments. The first container system will launch with SV Werder Bremen in summer 2026. Waste operator ALBA/Bral and Hamburg’s 105Viertel are further pilot partners with significant rollout potential.

ALGORA

MATERIA

MOTIVATION

TEAM

FACTURA

ENERGIA

Anike von Gagern

STELLA

Kathrin Weiß

115

HYDRODESAL WE OFFER AN APPROACH FOR A HUMAN RIGHT0 LOW-COST WATER SUPPLY. NEXT-GEN MATERIALS

COMPANY DETAILS LOCATION Mainz, Germany

ESTABLISHED NO

TRL TRL 5

FUNDING DETAILS FUNDING STAGE PRE-SEED

116

WEBSITE www.hydrodesal.uni-mainz.de

We use thermally switchable hydrogels that take up, desalinate, and release water, simply driven by Earth’s day-and-night temperature oscillation. These may be used in simple devices for water-supply at an individual household-scale.

COMPUTA

We develop an approach for people in small settlements in dry regions with access to the sea but no access to large desalination plants to selfsupply with desalinated water. Our process is driven simply by Earth’s day-and-night temperature oscillation; naturally and free of charge, for a human right: access to clean water.

VITALA

APPROACH

STATUS In a previous project stage funded by the German federal ministry BMBF, we have developed a laboratory-scale demonstrator setup. Now, we use that to evaluate our gel materials and the water product quality in a one-year test with daily runs, like anticipated in actual use. Along with that, we develop a device prototype for subsequent field testing.

ALGORA

MATERIA

MOTIVATION

TEAM

STELLA

FACTURA

ENERGIA

Sebastian Seiffert

117

ING3D THE MINERAL-BASED 3D PRINTING SOLUTION OF THE FUTURE. NEXT-GEN MATERIALS

COMPANY DETAILS LOCATION Fürth, Germany

ESTABLISHED NO

WEBSITE www.ing3d.de

TRL TRL 2

PATENTS GRANTED 1

EMPLOYEES 5

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED 10,000,000 EUR

PRIVATE FUNDING - EU &,000,000 EUR

118

REVENUE 3&0,000 EUR

ING3D disrupts construction with a unique lasersintering process for 3D printing mineral materials. Unlike heavy concrete, our approach creates ultra-lightweight, porous structures that are non-flammable (A1) and fully recyclable. By automating complex geometries, we minimize material use while maximizing thermal and acoustic insulation.

COMPUTA

Problem: Traditional materials are either too heavy or lack the fire resistance and insulation needed for sustainable, safe infrastructure.

Solution: Our technology uses mineral 3D printing to create ultra-lightweight, non-flammable, and 100% recyclable structures.

Vision: We empower industries to build greener and safer.

VITALA

APPROACH

STATUS ING3D has successfully transitioned from a PoC prototype to industrial application. Key milestones include receiving a groundbreaking patent for binderfree mineral 3D printing in 2025 and proving scalability through industrial pilot projects in furnace insulation and facade greening. Our technology is now ready for serial production.

ALGORA

MATERIA

MOTIVATION

TEAM

STELLA

FACTURA

ENERGIA

David Manjura

119

LANTHACYCLE LANTHAGEN BIO LTD IS A BIOTECHNOLOGY COMPANY FROM MANCHESTER THAT DEVELOPS ENGINEERED BIOLOGICAL SYSTEMS USING A BESPOKE MACHINE LEARNING PLATFORM TO RECOVER CRITICAL METALS FROM COMPLEX WASTE STREAMS. NEXT-GEN MATERIALS

COMPANY DETAILS LOCATION Manchester, England

ESTABLISHED YES

TRL TRL 4

EMPLOYEES 6

FUNDING DETAILS FUNDING STAGE PRE-SEED

120

WEBSITE

www.linktr.ee/lanthagenbio

We have engineered a suite of „Biomagnets“, or engineered proteins and peptides that can selectively bind REEs and other critical metals from electronic waste recycling feedstocks. These will be supported within traditional chemical engineering technologies, that sit within current process flows; harvesting REEs directly from the leachate.

COMPUTA

We at LanthaGen, aim to help countries on-shore critical mineral supply chains by re-mining from urban mines, driven by biology, nature‘s original miners.

VITALA

APPROACH

STATUS As a start up, conceptualised in our free time during our PhDs, LanthaGen has gained significant traction in 6 months. We have actively engaged with policy makers and worked closely with the Department of Business and Trade to forge collaborations, and scope markets globally.

ALGORA

MATERIA

MOTIVATION

Sahara Bhanot

FACTURA

Ellie Goulding

STELLA

Dan Healy

ENERGIA

TEAM

121

LEVEL NINE WE ARE DEVELOPING NEXT-GENERATION INDUSTRIAL CATALYSTS TO CONVERT LOCALLY ABUNDANT BIO-BASED FEEDSTOCKS INTO CHEMICAL BUILDING BLOCKS THAT OUTPERFORM PETROCHEMICALS ON BOTH COST AND PERFORMANCE. NEXT-GEN MATERIALS

COMPANY DETAILS LOCATION Berlin, Germany

ESTABLISHED YES

TRL TRL 6

EMPLOYEES 14

WEBSITE www.levelninelabs.com

FUNDING DETAILS FUNDING STAGE SEED

PRIVATE FUNDING - EU 5,000,000 EUR

122

PUBLIC FUNDING &,600,000 EUR

We re-imagine enzymes from first principles. Our nanozymes are bio-inorganic catalysts that mimic the active site of an enzyme, but with greater robustness to harsh conditions. This unlocks highly efficient, mild, lowcost chemical processes.

COMPUTA

Chemical companies lack the technologies to produce chemicals from biobased feedstocks profitably and at scale. Our nanozymes offer the precision of enzymes with increased robustness, creating the ultimate catalyst for industrial biobased chemistry.

VITALA

APPROACH

STATUS We have two nanozymes in the pipeline. The first one produces low-cost aromatic bio-polyols for the PU industry. The latter is focused on solving one of the “holy grails” of enzyme catalysis to produce the world’s first perfect drop-in bio-diesel solution

ALGORA

MATERIA

MOTIVATION

FACTURA

Emily Sheridan

STELLA

Seadna Quigley

ENERGIA

TEAM

123

LIGNILABS LIGNILABS DEVELOPS BIO-BASED LIGNIN MICROCAPSULES THAT RELEASE ACTIVE INGREDIENTS PRECISELY – FOR SUSTAINABLE AND BIOBASED CROP PROTECTION AND FLAME RETARDANTS. NEXT-GEN MATERIALS

COMPANY DETAILS LOCATION Mainz, Germany

ESTABLISHED YES

WEBSITE www.lignilabs.de

TRL TRL 4

PATENTS GRANTED 3

EMPLOYEES 7

FUNDING DETAILS FUNDING STAGE PRE-SEED

REVENUE 456,000 EUR

PUBLIC FUNDING 1,017,000 EUR

124

PRIVATE FUNDING - EU 450,000 EUR

LigniLabs GmbH has developed a groundbreaking platform technology for bio-based micro capsules based on lignin. The aim is to pave the way for targeted plant medicine by producing plant vaccines and to fundamentally change numerous other sectors, such as the construction industry, with bio-based flame-retardant formulations.

COMPUTA

Climate change, toxic chemicals and unsustainable agriculture threaten health and ecosystems, while the EU Green Deal bans many solutions. Our biobased technology enables controlled release of active substances, replacing synthetic encapsulation. It enables sustainable crop protection and halogen-free flame retardants and is scalable.

VITALA

APPROACH

STATUS In summer 2025 we have received a €1mn grant from SPRIND. Apart from that we have acquired a regional grant of €100k and we have closed a Business Angel round of €450k through a convertible loan agreement. Since then we have approached ca. 70 potential customers. A couple of them are currently testing our inital flame retardant product.

ALGORA

MATERIA

MOTIVATION

Frederik Wurm

Yannick Fröder

FACTURA

Alexander Throm

STELLA

Justin Grabow

ENERGIA

TEAM

125

MIMOTYPE MIMOTYPE TAPS INTO NATURE‘S OPEN SOURCE CODE TO CREATE CHEAPER, BETTER AND CLEANER MATERIALS FOR BIO-INSPIRED TECHNOLOGIES. NEXT-GEN MATERIALS

COMPANY DETAILS LOCATION Berlin, Germany

ESTABLISHED YES

TRL TRL 5

EMPLOYEES 4

WEBSITE www.mimotype.org

FUNDING DETAILS FUNDING STAGE PRE-SEED

FUNDING NEEDED 3,000,000 EUR

PRIVATE FUNDING - EU 700,000 EUR

PUBLIC FUNDING &,000,000 EUR

126

REVENUE 300,000 EUR

Advanced 3D tissue scaffolds create structural shapes but immediately limit biological insight. Once printed, researchers cannot monitor scaffold degradation, ECM deposition, remodeling, or transitions in stiffness without destructive or invasive techniques. This lack of internal visibility slows development and reduces reproducibility.

COMPUTA

Mimotype enables drug developers to transform organoids into standardized, reproducible assets via proteinbased sensing platforms.

VITALA

APPROACH

STATUS Mimotype’s Protein Integrated Sensing Matrix (PRISM) integrates fluorescentprotein based biosensors into a diverse set of organoid-compatible hydrogels (collagen, silk fibroin, synthetic polymers, bacterial nanocellulose). The PRISM pipeline has been developed by Mimotype over two years of internal R&D.

ALGORA

MATERIA

MOTIVATION

TEAM

FACTURA

ENERGIA

Claudio Flores

STELLA

Danilo Flores

127

OLIMENT USING ZERO-CARBON OLIVINE INSTEAD OF LIMESTONE TO CATER THE WORLDS DEMAND FOR CONCRETE. NEXT-GEN MATERIALS

COMPANY DETAILS LOCATION Espenhain, Germany

ESTABLISHED YES

WEBSITE www.oliment.com

TRL TRL 5

PATENTS GRANTED 6

EMPLOYEES 29

FUNDING DETAILS FUNDING STAGE SERIES A

FUNDING NEEDED 10,000,000 EUR

PUBLIC FUNDING 10,&50,000 EUR

128

PRIVATE FUNDING - EU 4,750,000 EUR

Oliment is a completely new type of cement based on magnesium silicate.

The binder can be produced in a fully carbon neutral manufacturing process while offering competitive costs, performance, characteristics and scalability.

COMPUTA

Oliment - the cement of the future - a Co2 neutral building material.

VITALA

APPROACH

STATUS Oliment is characterized by the high availability of its raw material (serpentinite) without CO₂ emissions, lower energy consumption and compliance with all industry-standard requirements. An application for general building approval has been submitted. The goal is to transition from the pilot plant to industrial-scale production.

ALGORA

MATERIA

MOTIVATION

TEAM

FACTURA

ENERGIA

Frank Bellmann

STELLA

Alexander Butt

129

TURBOO GREEN STEEL FOR CONSTRUCTION. NEXT-GEN MATERIALS

COMPANY DETAILS LOCATION Berlin, Germany

ESTABLISHED YES

WEBSITE www.turboo.world

TRL TRL 6

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED -,500,000 EUR

130

PRIVATE FUNDING - EU 50,000 EUR

Our next step is establishing a pilot production for high-performance TURBOO beams. In existing woodprocessing factories these elements are further developed into hybrid beams and slabs for pilot buildings.

Scaling will follow through TURBOO OS, a digital platform enabling standardized production and global licensing.

COMPUTA

The construction sector generates major CO₂ emissions, mainly from steel and concrete. TURBOO develops a high-performance material that can replace or reduce steel in many structural applications. We transform bamboo the fastest growing plant on Earth, reaching up to 1 m per day in Brazil—into strong, lightweight, low-carbon structures.

VITALA

APPROACH

STATUS TURBOO is currently in the pilot development phase (TRL 6). Material concepts and product designs have been validated by accredited laboratories and SPRIND through small-series production and lab testing. A pavilion at the Futurium marks the first built structure. The next step is establishing pilot production in Brazil to realize pilot buildings.

ALGORA

MATERIA

MOTIVATION

TEAM

STELLA

FACTURA

ENERGIA

Harry Knoll

131

WEEEFFICIENT WEEEFFICIENT DEVELOPS MODULAR, SCALABLE RECYCLING TECHNOLOGIES AT HZDR TO RECOVER PRECIOUS AND STRATEGIC METALS FROM ELECTRONIC WASTE IN AN ENERGY-EFFICIENT AND ENVIRONMENTALLY FRIENDLY WAY. NEXT-GEN MATERIALS

COMPANY DETAILS LOCATION Dresden, Germany

ESTABLISHED NO

TRL TRL 3

PATENTS GRANTED 2

132

EMPLOYEES 8

WEEEfficient combines mechanical pre-processing, flotation, and novel carrier magnetic separation to recover critical metals from e-waste. The process is scalable, low-impact, and enables recovery of materials currently lost in conventional recycling.

COMPUTA

Electronic waste is the fastest-growing waste stream, yet its critical metals remain largely lost. WEEEfficient is unlocking this untapped resource through scalable, low-impact technologies. Our vision is to turn e-waste into a strategic supply and strengthen Europe’s resource independence.

VITALA

APPROACH

MATERIA

MOTIVATION

STATUS

ALGORA

WEEEfficient is currently in early-stage development under SPRIN-D funding, with initial validation of key process steps completed. The project is now advancing towards pilot-scale demonstration, with a planned spin-out in 2026.

Himanshu Kachroo

FACTURA

Zahra Nourizenouz

STELLA

Ali Hassan

ENERGIA

TEAM

133

WESORT.AI WESORT.AI IS AN INNOVATIVE TECHNOLOGY COMPANY SPECIALISING IN SYSTEMS FOR THE PRECISE ANALYSIS AND SORTING OF WASTE OBJECTS USING ARTIFICIAL INTELLIGENCE AND STATE-OF-THE-ART DEEP SENSOR TECHNOLOGY. NEXT-GEN MATERIALS

COMPANY DETAILS LOCATION Würzburg, Germany

ESTABLISHED YES

WEBSITE www.wesort.ai

TRL TRL 4

PATENTS GRANTED 1

EMPLOYEES 15

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED 10,000,000 EUR

PRIVATE FUNDING - EU 4,000,000 EUR

PUBLIC FUNDING 3,000,000 EUR

134

REVENUE 1,000,000 EUR

With its AI-powered sorting technology, WeSort.AI enables the efficient separation of materials such as batteries and electronic waste, allowing valuable critical raw materials to be recovered. This contributes significantly to reducing strategic dependence on critical raw materials.

A disruptive approach sorts CRMs on dust level.

COMPUTA

WeSort.AI is an innovative technology company specializing in systems for the precise analysis and sorting of waste materials using artificial intelligence and state-of-the-art deep sensor technology to prevent fires & recover EUs critical raw materials.

VITALA

APPROACH

STATUS WeSort.AI has already been awarded the German Founders Award and is successfully deploying its first sorting systems with partners such as PreZero. The company is convinced that a true circular economy can only be achieved through proper waste sorting and is passionately committed to this goal.

ALGORA

MATERIA

MOTIVATION

Simon Thiemann

Robin Wolf

FACTURA

Johannes Laier

STELLA

Nathanael Laier

ENERGIA

TEAM

135

AURYAL AURYAL CREATES A HUMAN ALIGNED SUPERINTELLIGENCE THAT MAKES AI ACT IN CONJUNCTION WITH HUMANKIND. ARTIFICIAL INTELLIGENCE

COMPANY DETAILS LOCATION Cottbus/Berlin, Germany

ESTABLISHED YES

TRL TRL 7

EMPLOYEES 10

FUNDING DETAILS FUNDING STAGE PRE-SEED

REVENUE &00,000 EUR

136

WEBSITE www.auryal.com

We unlock neuro data collection at scale in real-world scenarios to observe and learn from the human cognition to provide human judgement as Reinforcement Learning policy for training Generative AI models such as VLA and LLM.

COMPUTA

AURYAL‘s vision is to bridge the gap between high-fidelity neurotechnology and the industrial scaling of physical intelligence. The company defines a new category: from pure neurotech to physical AI training infrastructure. The ultimate objective is to provide the Human Alignment Layer as an infrastructure across the global AI stack.

VITALA

APPROACH

MATERIA

MOTIVATION

STATUS

ALGORA

In 12 months, we have developed various PoCs, published groundbreaking research papers and are now moving towards validation partnerships with the world‘s leading AI frontier labs.

Milan Padilla

FACTURA

Simon Vogt

STELLA

Thorsten Zander

ENERGIA

TEAM

137

EXALSIUS THE EXALSIUS TEAM IS BUILDING A SYSTEM TO SIMPLIFY ACCESS TO COMPUTING RESOURCES, PARTICULARLY FOR AI. ARTIFICIAL INTELLIGENCE

COMPANY DETAILS LOCATION Berlin, Germany

ESTABLISHED YES

TRL TRL 5

EMPLOYEES 10

WEBSITE www.exalsius.ai

FUNDING DETAILS FUNDING STAGE PRE-SEED

FUNDING NEEDED 5,000,000 EUR

138

REVENUE 750,000 EUR

Our vendor-agnostic control plane abstracts fragmented, geo-distributed GPU servers into a unified compute pool. Using advanced orchestration, operation, and auto-recovery, we enable AI scaling across distributed data centers. Our strategy scales via strategic subcontracting, providing a sovereign, EU multi-vendor alternative to US hyperscalers.

COMPUTA

European organizations face a highly fragmented GPU infrastructure market, which is stalling AI progress.

Exalsius pools distributed, heterogeneous compute resources into a unified cloud, enabling to scale AI on existing hardware. As a decoupling layer we prevent vendor lock-in, secure strategic autonomy, and technological sovereignty.

VITALA

APPROACH

STATUS Secured €1.6M in federal funding (SPRIN-D) and active revenue traction. Key milestones include multi-cloud AI deployments for global research labs and delivering secure, sovereign environments for the public sector. We are currently advancing through several regional and national tenders for critical AI infrastructure.

ALGORA

MATERIA

MOTIVATION

Sören Becker

FACTURA

Odej Kao

STELLA

Alexander Acker

ENERGIA

TEAM

139

IT‘S REAL.MEDIA ITSREAL.MEDIA DETECTS AI-GENERATED MEDIA WITH --.%%2 ACCURACY THROUGH MULTI-SIGNAL FORENSICS AND SEMANTIC PATTERN ANALYSIS, A FUTUREPROOF, WHOLE-IMAGE UNDERSTANDING ENGINE. ARTIFICIAL INTELLIGENCE

COMPANY DETAILS LOCATION Mannheim, Germany

ESTABLISHED YES

TRL TRL 8

EMPLOYEES 4

FUNDING DETAILS FUNDING STAGE PRE-SEED

FUNDING NEEDED 1,&00,000 EUR

140

WEBSITE www.itsreal.media

We analyze the entire image through three fused layers: 150+ technical signal features (wavelets, noise, spectral anomalies), semantic pattern analysis using visual language models trained on audiovisual expert knowledge, and metadata & provenance checks, all combined in a stacked ensemble meta-model.

COMPUTA

AI-generated media floods the internet, making it impossible to tell what‘s real. Insurers lose money to fake claims, platforms lose user trust, and society loses shared reality. Our crusade: to create genuinely real spaces in a slope and fake dominated world, where authentic media can be proven, not just assumed.

VITALA

APPROACH

STATUS Winner of the SPRIND Funke Deepfake Detection & Prevention Challenge. Production-ready API deployed. Benchmarked under real-world conditions: compressed, cropped, screenshot and social-media-processed images against 25+ generators and 20,000 tagged images. Now entering pilot phase with first B2B customers.

ALGORA

MATERIA

MOTIVATION

Agustín Tajani

FACTURA

Agustin Russo

STELLA

Christoph Behl

ENERGIA

TEAM

141

METABUILD THE TEAM DEVELOPS THE WORLD‘S LEADING TECHNOLOGY FOR BUILDING SIMULATION AND COST OPTIMIZATION. ARTIFICIAL INTELLIGENCE

COMPANY DETAILS LOCATION Berlin, Germany

ESTABLISHED YES

TRL TRL 8

EMPLOYEES 15

FUNDING DETAILS FUNDING STAGE SERIES A

142

WEBSITE www.metabuild.de

We build on an open, interoperable platform that structures building data over the full lifecycle, connects simulations, cost and external tools. A seamless integration with a browserbased 3D modelling tool allows for efficient model interaction and data visualization.

COMPUTA

The real estate sector suffers from siloed data that blocks efficient operation and renovation, raises costs and slows climate action. Owners, operators, planners and cities are in need of a solution that unlocks open, interoperable building data for smarter, faster and more sustainable decisions.

VITALA

APPROACH

STATUS Key achievements to date include the core Metabuild platform, integrated simulation and calculation workflows, and PoCs for data model expandibility, IFC export and DIN 18599 connection. We have also defined validation paths for USD, CityGML and data-quality scorings.

ALGORA

MATERIA

MOTIVATION

TEAM

FACTURA

ENERGIA

Julius Jacob

STELLA

Tariq Kaddoura

143

MIMIR MULTI-AGENT SYSTEMS LACK A CRITICAL LAYER0 OPTIMAL AGENT SELECTION. MIMIR DEVELOPS A DYNAMIC ROUTING SYSTEM BASED ON PERFORMANCE, COST, AND EU COMPLIANCE. ARTIFICIAL INTELLIGENCE

COMPANY DETAILS LOCATION Tübingen, Germany

ESTABLISHED YES

TRL TRL 3

EMPLOYEES 6

FUNDING DETAILS FUNDING STAGE PRE-SEED

FUNDING NEEDED 1,000,000 EUR

144

WEBSITE www.mimir.fit

We evaluate AI agents across annotated datasets, supplemented by our own benchmarks for performance, cost, and compliance. On this data, we train a retrieval-based classifier that predicts per-query, per-agent quality scores. Unlike binary routers, we provide quantitative, aspect-level predictions enabling transparent, auditable agent selection.

COMPUTA

Choosing the right AI agent is critical, yet today it‘s done ad hoc. Even major players use unsophisticated routing, and legal compliance is rarely verified. As EU regulation tightens, this becomes existential. MIMIR democratizes this choice with an intelligent routing layer based on rigorous evaluation data, with EU compliance built in.

VITALA

APPROACH

STATUS Working predictor prototype, live evaluation pipeline on real data, benchmarking environment built. First pilot customer engaged with tailored benchmarking solution. Team of 4 co-founders and 2 employees. In SPRIND-funded validation phase, seeking Pre-Seed funding to scale the team and go to market.

ALGORA

MATERIA

MOTIVATION

FACTURA

Maximilian Bitterwolf

STELLA

Julian Bitterwolf

ENERGIA

TEAM

145

NEOBIM AI-POWERED END-TO-END PLATFORM TO PLAN AND BUILD BETTER BUILDINGS. ARTIFICIAL INTELLIGENCE

COMPANY DETAILS LOCATION Karlsruhe, Germany

ESTABLISHED YES

TRL TRL 5

EMPLOYEES 33

WEBSITE www.neobim.ai

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED 4&,000,000 EUR

PRIVATE FUNDING - EU 6,000,000 EUR

PUBLIC FUNDING &,000,000 EUR

146

PRIVATE FUNDING &,000,000 EUR

NeoBIM is an end-to-end browser platform for the entire building lifecycle, from early feasibility to design and documentation. At its core is a Unified Description Model of a Building—a structured representation editable by humans and AI—enabling automated workflows, consistent data, and seamless collaboration.

COMPUTA

The AEC industry relies on fragmented tools for feasibility, design, documentation, and analysis. Data is constantly recreated and workflows are disconnected, slowing projects and limiting AI use. An end-to-end platform with a shared building representation can fundamentally accelerate how buildings are planned.

VITALA

APPROACH

STATUS We are developing NeoBIM through several focused AEC tools, two of them are already gaining early user traction. These tools share the same underlying architecture and are being integrated behind the scenes into a unified platform.

Another tool launches in April, with the full platform planned later this year.

ALGORA

MATERIA

MOTIVATION

TEAM

FACTURA

ENERGIA

Florian Marthaler

STELLA

Moritz Luck

147

NEOCLEAR A NEXT-GEN EUROPEAN CCP REPATRIATING 31&0 TRILLION IN EURODENOMINATED DERIVATIVES CLEARING POST-BREXIT, STRENGTHENING EUROPE’S FINANCIAL SOVEREIGNTY. BACKED BY A CLIENT GROUP REPRESENTING 36 TRILLION AUM. ARTIFICIAL INTELLIGENCE

COMPANY DETAILS LOCATION London, England

ESTABLISHED YES

TRL TRL 4

FUNDING DETAILS FUNDING STAGE PE-SEED

FUNDING NEEDED 3,000,000 EUR

148

WEBSITE www.neoclear.uk

NeoClear puts clients first, and is building a new Clearing House based on their requirements. We have built an ecosystem and working groups that include the largest banks, buyside organizations, solution providers, politicians and market experts, allowing us to deliver rapid progress at a fraction of the cost of other market infrastructures.

COMPUTA

NeoClear believes in servicing clients first, and that innovation must be bold and have no bounds. With a small team of people, we have made immense progress by driving forward our vision to build new market infrastructure from the ground up. Ultimately, NeoClear will deliver essential services to the market at a fraction of the legacy cost.

VITALA

APPROACH

STATUS NeoClear has spent 2 years creating the blueprint for building and launching a licensed Clearing House in Europe, including full risk, infrastructure and operating models, draft regulatory license application, creating working groups of future members, and obtaining full European regulatory and political support.

ALGORA

MATERIA

MOTIVATION

Michael Wellenbeck

Olivier Raevel

FACTURA

Helena Frumson

STELLA

Paul Whitehead

ENERGIA

TEAM

149

PANOCULAR.AI SYMPHONYLEARN ENABLES EFFICIENT, DECENTRALIZED AI TRAINING WITH DATA-DRIVEN OPTIMIZATION AND DIFFERENTIAL PRIVACY - FAST, SCALABLE AND PRIVACY-FRIENDLY. ARTIFICIAL INTELLIGENCE

COMPANY DETAILS LOCATION Darmstadt, Germany

ESTABLISHED YES

TRL TRL 5

EMPLOYEES 11

WEBSITE www.panocular.ai

FUNDING DETAILS FUNDING STAGE PRE-SEED

FUNDING NEEDED 100,000 EUR

150

REVENUE 5&0,000 EUR

PanoVLM is a purpose-built, ultra-efficient vision-language model that runs on small-scale processors without sacrificing performance. Using our novel decentralized training approach, we significantly reduced the cost and compute needed to build advanced custom AI models for different robotic use cases.

COMPUTA

PanocularAI is a European frontier AI lab focused on building decentralized, efficient, custom multimodal models for edge deployment in autonomous systems—helping SMEs adopt AI faster through automated optimization, lower costs, and built-in compliance.

VITALA

APPROACH

STATUS PanocularIA is an award-winning startup (Hessischer Gründerpreis and WLOUNGE Rising Star). We built PanoVLM from scratch are testing it with two pilot customers, and have open-sourced our decentralized training platform so clients can train the model securely on their in-house data (supported by SPRIND Composite learning challenge).

ALGORA

MATERIA

MOTIVATION

TEAM

FACTURA

ENERGIA

Sören Heß

STELLA

Arya Mazaheri

151

PLANETARY COMPUTE PROTOCOL WE DEVELOP A DISTRIBUTED AI TRAINING FRAMEWORK IN ZIG USING AN ACTOR MODEL, ENABLING CROSSHARDWARE ML AND SOLVING COMMUNICATION AND SCALABILITY CHALLENGES IN FEDERATIONS. ARTIFICIAL INTELLIGENCE

COMPANY DETAILS LOCATION Les Lilas, France

ESTABLISHED YES

TRL TRL 6

EMPLOYEES 4

WEBSITE www.deltawave.fr

FUNDING DETAILS FUNDING STAGE PRE-SEED

FUNDING NEEDED 10,000,000 EUR

PUBLIC FUNDING &00,000 EUR

152

PRIVATE FUNDING - EU 150,000 EUR

EVE is a multi-agent AI system that orchestrates workflows for literature search, molecule/protein engineering, BioML models, bioinformatics tools, bio database search, and lab integration. PCP, a distributed protocol, deploys EVE on heterogeneous hardware for efficient ML training/ inference, using shared knowledge graphs and RL topologies.

COMPUTA

Researchers face a complex landscape in tasks like drug discovery, hindered by siloed tools and data, manual workflows, and limited hardware scalability for AI models. This affects scientists, companies, and patients.

Developing EVE & PCP is crucial to accelerate innovation, reduce costs, and enable breakthroughs.

VITALA

APPROACH

STATUS Key achievements: Fully production-ready EVE platform for advanced biotech workflows. PCP advanced to stage 2 of SPRIND Composite Learning Challenge. PoC with French pharma Servier to validate real-world application in drug research. Supported by BPIfrance.

ALGORA

MATERIA

MOTIVATION

Atabey Ünlü

Ahmet Celebi

FACTURA

Florence Allouche Aknin

STELLA

Phil Rohr

ENERGIA

TEAM

153

RULEMAPPING RULEMAPPING MAKES COMPLEX RULES EASY – TURNING TEXT INTO VISUAL, MACHINE-READABLE DECISION TREES AS AN OPEN STANDARD THAT IS CLEAR, CONSISTENT, AND TRACEABLE. ARTIFICIAL INTELLIGENCE

COMPANY DETAILS LOCATION Berlin, Germany

ESTABLISHED YES

TRL TRL 9

EMPLOYEES 30

WEBSITE www.rulemapping.com

FUNDING DETAILS FUNDING STAGE SERIES B

FUNDING NEEDED 30,000,000 EUR

PRIVATE FUNDING - EU 4,%50,000 EUR

PUBLIC FUNDING 7,000,000 EUR

154

REVENUE 1,700,000 EUR

Rulemapping makes law instantly executable: we translate statutes into visual, machine-readable decision logic. A hybrid Rule AI (legal reasoning + AI) enables transparent, compliant automation and pushes updates to live systems within minutes.

COMPUTA

A state that can act: sovereign, efficient, accountable. Our vision is a public sector where legal logic is instantly executable and explainable, powering fast, fair decisions, resilient services, and democratic control— without surrendering sovereignty to black-box code.

VITALA

APPROACH

MATERIA

MOTIVATION

STATUS

ALGORA

Law as Code anchored in the federal Modernisation Agenda; Rulemapping named as the implementation path. €12m funding with SPRIND. AI pilot for faster building permits in Thuringia. Further state pilots and first justice applications.

Stephan Breidenbach

FACTURA

Till Behnke

STELLA

Ina Remmers

ENERGIA

TEAM

155

WEIGHT SPACE LABS WE WANT TO TRAIN A FOUNDATION MODEL OF NEURAL NETWORKS TO REPLACE PRETRAINING WITH ON DEMAND WEIGHT GENERATION. ARTIFICIAL INTELLIGENCE

COMPANY DETAILS LOCATION St. Gallen, Switzerland

ESTABLISHED NO

TRL TRL 6

FUNDING DETAILS FUNDING STAGE PRE-SEED

156

EMPLOYEES 6

To accomplish this we use the weights of populations of neural networks (=model zoos) as input for representation learning. This is done similarly to language models or image models but instead of words, we process weights, instead of sentences, we process neural network layers and instead of books, we process neural network models.

COMPUTA

Instead of training from data, we propose to train neural networks from models itself and therefore potentially aggregate the knowledge encoded in over 2 million models on platforms as Hugging Face into one single foundation model of neural networks.

VITALA

APPROACH

MATERIA

MOTIVATION

STATUS

ALGORA

We have developed Weight Space Learning and have published multiple works on that topic with the most recent work showing an speed up of training by 3040x for Remote Sensing Foundation Models.

TEAM

FACTURA

ENERGIA

Boris Knyazev

STELLA

Damian Borth

157

%INKS SETTING A NEW STANDARD FOR BATTERY MANUFACTURING. FUTURE ENERGY

COMPANY DETAILS LOCATION Zurich, Switzerland

ESTABLISHED YES

TRL TRL 6

EMPLOYEES 11

WEBSITE www.8inks.com

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED 15,000,000 EUR

REVENUE &00,000 EUR

PRIVATE FUNDING %,000,000 EUR

PRIVATE FUNDING - EU 500,000 EUR

PUBLIC FUNDING 4,500,000 EUR

158

8inks turns multilayer electrode designs into industrially relevant battery products. Our solution enables multiple functional layers in one production step, improving battery performance while reducing manufacturing cost, footprint and energy use, with retrofit potential for existing lines.

COMPUTA

Battery manufacturing still forces trade-offs between cost, energy density, charging and scalability. 8inks enables a new production standard that unlocks better battery architectures and makes next-generation batteries cheaper, higher-performing and manufacturable at scale.

VITALA

APPROACH

STATUS 8inks has validated multilayer electrodes across LFP, graphite, silicon and solid-state systems, built and tested pouch cells, demonstrated industrial-scale feasibility, secured paid PoCs with leading OEMs and cell manufacturers, and is now advancing toward market entry with a retrofit production solution for battery manufacturers.

ALGORA

MATERIA

MOTIVATION

Karl-Philipp Schlichting

FACTURA

Paul Baade

STELLA

Leon Baade

ENERGIA

TEAM

159

BATENE A 330B2 MARKET 4 BUILT INTO EVERY BATTERY. PRICED AT MARKET RATE. 30% GROSS MARGIN BUILT IN. HIGH POWER AND HIGH ENERGY IN ONE CELL. NO TOXIC SOLVENTS. DROP-IN COMPATIBLE FOR ALL BATTERY CHEMISTRIES. FUTURE ENERGY

COMPANY DETAILS Wendlingen am Neckar, Germany

ESTABLISHED YES

WEBSITE www.batenetec.com

TRL TRL 5

PATENTS GRANTED 18

EMPLOYEES 16

LOCATION

FUNDING DETAILS FUNDING STAGE SEED

REVENUE 1-6,600 EUR

160

PRIVATE FUNDING - EU 5,000,000 EUR

Starting from molten metal: ultra-fine metal fibers are formed into BateneFleece — a 3D current collector that replaces conventional foil. The fleece eliminates the transport bottleneck behind the power-energy trade-off.

BateneDry, a fluorine-free binder, enables solvent-free dry processing for any electrode. Drop-in compatible, all-chemistry.

COMPUTA

Every battery can be better. Batene develops the electrode platform that makes it possible — all-chemistry, scalable, built from European deeptech. The mission: to set the new standard for electrodes, globally.

VITALA

APPROACH

STATUS Lab production line operational. Pouch cell demonstrators validated. Industrial validation launched 2026 with a leading automotive OEM. Development agreements with battery manufacturers underway. €17.7M raised to date including €5M Seed Extension (2026). 22 patent families (granted and pending).

ALGORA

MATERIA

MOTIVATION

Thanh Nguyen Thi Dieu

Christian Boehm

FACTURA

Martin Möller

STELLA

Joachim Spatz

ENERGIA

TEAM

161

CARBON.ONE C1 IS LEVERAGING NOVEL CHEMISTRY TO PRODUCE METHANOL, ONE OF THE LARGEST CHEMICAL COMMODITIES ON THE PLANET, AT AN UNBEATABLE PRICE POINT ADDRESSING EMERGING GREEN FUEL MARKETS SUCH AS AVIATION AND SHIPPING. FUTURE ENERGY

COMPANY DETAILS LOCATION Berlin, Germany

ESTABLISHED YES

WEBSITE www.carbon.one

TRL TRL 6

PATENTS GRANTED 2

EMPLOYEES 30

FUNDING DETAILS FUNDING STAGE SERIES A

FUNDING NEEDED 10,000,000 EUR

PUBLIC FUNDING %,000,000 EUR

162

PRIVATE FUNDING - EU &%,400,000 EUR

C1 uses computer simulation to invent novel catalysts based on nonprecious metals. Our homogeneous methanol catalysis works at lower temperature (120C) and pressure (20bar), is highly selective and load-flexible. It produces no water and reduces green hydrogen cost in e-Methanol production by 33%.

COMPUTA

The Iran war highlights the world’s reliance on fossil fuels. We can reduce this dependency by establishing a circular carbon economy based on green methanol. This is held back by methanol‘s 100-year-old production technology, optimized for centralized mega-sites. C1 solves this with costefficient, small-scale, decentralized methanol production.

VITALA

APPROACH

STATUS Continuous and fully automated production was proven in the Leuna100 pilot plant, producing hundred liters of methanol per day. C1 is currently planning a first-of-a-kind, 20 tons-per-day commercial demonstration plant which fully derisks the technology and enables the go-to-market via technology licencing. FID for the FOAK is scheduled for Q1 2027

ALGORA

MATERIA

MOTIVATION

Haik Mehmke

FACTURA

Mathias Mostertz

STELLA

Christian Vollmann

ENERGIA

TEAM

163

ELEMENTARHY LET’S MAKE GREEN HYDROGEN TRULY COST-EFFICIENT 4 WITH DEEP TECHNOLOGY AT ITS CORE. FUTURE ENERGY

COMPANY DETAILS LOCATION Hamburg, Germany

ESTABLISHED YES

WEBSITE www.elementarhy.com

TRL TRL 6

PATENTS GRANTED 3

EMPLOYEES 10

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED &,500,000 EUR

PUBLIC FUNDING 600,000 EUR

164

REVENUE 1-0,000 EUR

Scale proprietary plasma coating and MEA production process to MW stack production via pilot line upgrade, process optimization, and industrial transfer. Validate performance and durability in stack prototypes with pilot customers, reducing iridium usage by 95% while maintaining efficiency and increasing lifetime.

COMPUTA

Scaling hydrogen for a resiient netzero society as well as space exploring society.

VITALA

APPROACH

MATERIA

MOTIVATION

STATUS

ALGORA

Validated small-scale performance up to 100 cm2. Pilot-scale MEA capability established. Early customer engagement secured; moving toward MW-scale stack prototypes and industrial process scale-up.

Bernd Hetterscheidt

Martin Rohloff

FACTURA

Gunter Erfurt

STELLA

Gustav Sievers

ENERGIA

TEAM

165

GREENLYTE GREENLYTE MAKES E-FUELS BANKABLE WITH A FLEXIBLE, RESILIENT CO₂ AND HYDROGEN FEEDSTOCK PLATFORM THAT TURNS RENEWABLE INTERMITTENCY INTO A COST ADVANTAGE. FUTURE ENERGY

COMPANY DETAILS LOCATION Essen, Germany

ESTABLISHED YES

WEBSITE www.greenlyte.tech

TRL TRL 7

PATENTS GRANTED 3

EMPLOYEES 70

FUNDING DETAILS FUNDING STAGE SERIES A

FUNDING NEEDED 50,000,000 EUR

PUBLIC FUNDING &3,000,000 EUR

166

PRIVATE FUNDING - EU &5,000,000 EUR

Greenlyte decouples CO₂ capture from energy-intensive release: CO₂ is captured continuously and stored as bicarbonate, then converted with hydrogen when renewable power is abundant. Combined with off-grid renewables and co-location at existing plants, this cuts cost, boosts resilience, and enables rapid scale-up.

COMPUTA

Defossilisation in hard-to-abate sectors like aviation and shipping is essential, but these sectors cannot easily electrify. They need scalable, resilient e-fuel pathways – yet e-fuels remain too expensive, depend on scarce biogenic CO₂, and struggle with renewable intermittency.

VITALA

APPROACH

STATUS Greenlyte has logged 15,000+ operating hours across demonstrator and pilot facilities, built 10+ patent families (3 granted), secured over €1bn in offtake agreements, and is now advancing its FOAK plant in the Chempark Marl toward bankable industrial deployment.

ALGORA

MATERIA

MOTIVATION

Martin Schmickler

Peter Behr

FACTURA

Niklas Friederichsen

STELLA

Florian Hildebrand

ENERGIA

TEAM

167

MACROCARBON WE CREATE CARBON-NEGATIVE, OCEAN POSITIVE SUSTAINABLE AVIATION BIOFUELS AT COMPETITIVE PRICES FOR AIRLINES AND FUEL SUPPLIERS. FUTURE ENERGY

COMPANY DETAILS Las Palmas de Gran Canaria, Spain

ESTABLISHED YES

TRL TRL 5

EMPLOYEES 7

LOCATION

WEBSITE www.macrocarbon.world

FUNDING DETAILS FUNDING STAGE PRE-SEED

FUNDING NEEDED &,000,000 EUR

PUBLIC FUNDING 500,000 EUR

168

PRIVATE FUNDING 100,000 EUR

MacroCarbon uses a proprietary offshore cultivation system to grow seaweed. The biomass is harvested and converted via modular thermochemical processing—integrating vacuum and methane pyrolysis with a Fischer-Tropsch reactor. This strategy creates SAF.

COMPUTA

Aviation faces a critical shortage of sustainable feedstocks to meet EU ReFUEL mandates. MacroCarbon solves this by cultivating seaweed to produce carbon-negative fuel and materials. This is vital for de-fossilizing aviation.

VITALA

APPROACH

MATERIA

MOTIVATION

STATUS

ALGORA

In just 18 months, we have deployed our first aquafarm prototype and won the All4Zero SAF Challenge, leading to a Proof of Concept with industry giants Iberia, Repsol, and Airbus.

FACTURA

Jason Cole

STELLA

Mar Fernández-Méndez

ENERGIA

TEAM

169

RADICAL DOT RADICAL DOT CONVERTS MIXED PLASTIC WASTE INTO VALUABLE CHEMICAL BUILDING BLOCKS USING A LOW-TEMPERATURE CATALYTIC PROCESS – EFFICIENT, SCALABLE, RESOURCE-SAVING AND EMISSION-REDUCING. FUTURE ENERGY

COMPANY DETAILS LOCATION Munich, Germany

ESTABLISHED YES

TRL TRL 5

EMPLOYEES 10

WEBSITE www.radicaldot.com

FUNDING DETAILS FUNDING STAGE PRE-SEED

REVENUE &50,%04 EUR

PUBLIC FUNDING 3,%%0,000 EUR

170

PRIVATE FUNDING - EU &,700,000 EUR

Radical Dot converts mixed plastic waste into essential basic chemicals used across industry. By using waste as a low-cost carbon source, we reduce dependence on fossil feedstocks while staying cost-competitive at scale. Our focus is on scalable processes that can integrate into existing chemical infrastructure.

COMPUTA

Europe’s chemical industry is losing competitiveness due to high energy costs and dependence on fossil raw materials, threatening critical supply chains. We aim to rebuild a strong European chemical base by turning waste into low-cost chemical feedstocks and enabling a circular, resilient industrial model.

VITALA

APPROACH

STATUS We have successfully validated our core technology in lab and pilot systems, producing key chemical products from mixed plastic waste. A completed SPRIND validation project confirmed feasibility and scale-up potential. We are now working with industrial partners toward a demonstration plant as the next step.

ALGORA

MATERIA

MOTIVATION

FACTURA

Andreas Wagner

STELLA

Alexandre Kremer

ENERGIA

TEAM

171

SHIT&POWER SHIT&POWER CONVERTS INDUSTRIAL AND MUNICIPAL SLUDGE INTO CLEAN ENERGY AND REUSABLE ASH 4 DIRECTLY WHERE IT IS GENERATED. FUTURE ENERGY

COMPANY DETAILS LOCATION Berlin, Germany

ESTABLISHED YES

TRL TRL 6

EMPLOYEES 7

WEBSITE www.shit2power.de

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED &,500,000 EUR

PRIVATE FUNDING - EU 375,000 EUR

PUBLIC FUNDING 563,54- EUR

172

REVENUE 1&3,750 EUR

Shit2Power uses a proprietary, MLoptimized gasification system to process wet sludge directly on-site. Our standardized containerized plants reduce sludge volume by up to 90% and generate electricity and heat locally, combining waste treatment and energy production in one deployable system.

COMPUTA

We believe the future of sludge is not disposal, but energy — and Shit2Power is building the system that makes this transition scalable.

VITALA

APPROACH

STATUS TRL 6 validated technology, first paid pilot contract signed in December 2025.

Delivery is scheduled for June, operations start in August. In parallel, industrial customers are preparing PoCs with clear multi-site rollout potential, while our qualified pipeline across Germany and core EU continues to grow.

ALGORA

MATERIA

MOTIVATION

Cornelia Schwertner

FACTURA

Fabian Habicht

STELLA

Nina Heine

ENERGIA

TEAM

173

TELURA TELURA ADVANCES ELECTRIC IMPULSE DRILLING TECHNOLOGY, ENABLING FASTER AND MORE COST-EFFICIENT SUBSURFACE ACCESS TO DELIVER GEOTHERMAL ENERGY EVERYWHERE AND SUPPORT STRATEGIC INDUSTRIES. FUTURE ENERGY

COMPANY DETAILS LOCATION Munich, Germany

ESTABLISHED YES

WEBSITE www.telura.com

TRL TRL 5

PATENTS GRANTED 1

EMPLOYEES 13

FUNDING DETAILS FUNDING STAGE PRE-SEED

FUNDING NEEDED 15,000,000 EUR

174

PRIVATE FUNDING - EU 4,000,000 EUR

Built on over two decades of research, Telura’s electric impulse drilling uses high-voltage pulses to break rock from within, enabling faster, more cost-efficient access to geothermal resources independent of geology. We collaborate with leading research institutions (KIT, TU Dresden, ETH Zurich) and industrial partners to accelerate deployment.

COMPUTA

Energy sovereignty and secure energy supply are becoming Europe’s top priorities. Yet geothermal energy, always-on, emissions-free, and widely available, remains unscaled due to complexity and cost. Unlocking this vast resource is critical for energy independence, resilience to geopolitical shocks, and industrial competitiveness.

VITALA

APPROACH

STATUS Telura is focused on engineering systems that operate reliably at scale. The technology is being validated with four drilling systems in controlled environments, with first industrial partners and customers secured. Initial field pilots are planned for late 2026, marking the path to commercialization.

ALGORA

MATERIA

MOTIVATION

FACTURA

Andrew Welling

STELLA

Philipp Engelkamp

ENERGIA

TEAM

175

VIRIDIS RECYCLING FUTURE ENERGY

COMPANY DETAILS LOCATION Hanau, Germany

ESTABLISHED YES

TRL TRL 8

EMPLOYEES 14

WEBSITE www.viridis-recycling.de

FUNDING DETAILS FUNDING STAGE SERIES A

FUNDING NEEDED 5,000,000 EUR

PRIVATE FUNDING - EU 100,000 EUR

176

REVENUE 3,000 EUR

We use a high-voltage based recycling process without chemical- or thermal treatment, which is compared to hydrometallurgical and pyrometallurgical processes more effective.

We have lower opex, lower capex, lower impurities in blackmass and lower Carbon footprint.

COMPUTA

We want to establish our recycling process as state of the art for battery recycling. We want to close the recycling loop in Germany with our partners which are cell producers and pCam producers.

We produce the raw materials Germany and Europe needs for further economical and ecological development.

VITALA

APPROACH

STATUS We received an exclusive licence by Fraunhofer IWKS for the industrialization of our HydroPulse Battery Recycling process.

We are in contact with battery cell factories and with pcam producers who want to buy our blackmass. Pilotline 200 kg/h in use. Blackmass is cleaner than competitor‘s Industrial expansion with 1t/h per line ready to be buil

ALGORA

MATERIA

MOTIVATION

Dirk Brieke

Benny Balke-Grünewald

FACTURA

Timotheus Jahnke

STELLA

Jens Huber

ENERGIA

TEAM

177

WATER STUFF & SUN WATER STUFF & SUN DEVELOPS A SAFE, MODULAR H& BATTERY USING SPHERICAL STORAGE THAT SIGNIFICANTLY LOWERS HYDROGEN COSTS AND INFRASTRUCTURE NEEDS, ENABLING SCALABLE CLEAN ENERGY. FUTURE ENERGY

COMPANY DETAILS LOCATION Munich, Germany

ESTABLISHED YES

WEBSITE

TRL TRL 5

PATENTS GRANTED 6

EMPLOYEES 14

FUNDING DETAILS FUNDING STAGE SERIES A

FUNDING NEEDED 10,000,000 EUR

178

www.waterstuffandsun.com

The H2 Battery is a groundbreaking solution for hydrogen storage: safe, modular, and cost-efficient. It achieves high energy densities and enables a drastic simplification of infrastructure; a foundation for scalable, sustainable energy economy.

COMPUTA

The energy transition requires storing large amounts of energy and distributing them on demand. This makes a more efficient energy system based on a carrier indispensable: hydrogen.

Hydrogen must be safe and easy for consumers, supported by dual-use technology enabling efficient storage in products and an efficient distribution infrastructure.

VITALA

APPROACH

STATUS Currently, we are in development phase, with main concepts defined and first prototype running. Further focus on product & performance optimization, production scalability, next to planning a pilot project, business development effort and collaboration with industrial partners.

ALGORA

MATERIA

MOTIVATION

Alvaro Sousa

FACTURA

Jonas Flädjemark

STELLA

Thomas Korn

ENERGIA

TEAM

179

ABSORA A GROUNDBREAKING MATERIAL FOR LIGHTWEIGHT CONSTRUCTIONS, ACOUSTICS AND FILTRATION IS DEVELOPED BY ABSORA. INDUSTRIAL INNOVATION

COMPANY DETAILS LOCATION Berlin, Germany

ESTABLISHED YES

WEBSITE www.absora.eco

TRL TRL 4

PATENTS GRANTED 1

EMPLOYEES 11

FUNDING DETAILS FUNDING STAGE PRE-SEED

REVENUE &-0,000 EUR

PUBLIC FUNDING 6-4,000 EUR

180

PRIVATE FUNDING - EU 1,&50,000 EUR

STATUS Patents & design have been filed.

Successful practical applications: • An HVAC sound absorber was tested with 21% more attenuation and 40% less pressure loss than rock wool • Noise barrier w/ 3-5 times higher low-frequency absorption than rock wool • -5 dB (-68%) in a gas heater • Air intake of gas-fired power plant: -8 dB (-84%)

COMPUTA

Our material „HSA3“ addresses both, combining lightweight design and noise/vibration absorption w/o rock wool or foam. Its production process is cost-effectively using existing machinery, lowers market entry barriers & strengthens sustainable value chains across industry & SMEs.

VITALA

Air pollution & noise are the 2 most important health risks for humans: (1) Air pollution concerns mainly the reduction of CO2 in the atmosphere (2) Noise-induced sicknesses cause up to 1.6m (!) sick years per annum in Western Europe alone Moreover, Germany‘s metal industry is currently suffering.

We will contribute to changing that!

MATERIA

APPROACH

ALGORA

MOTIVATION

TEAM

STELLA

FACTURA

ENERGIA

Johannes Kotte

181

AEON ROBOTICS AEON ROBOTICS HAS DEVELOPED A ROBOT SYSTEM MODELED ON HUMANS THAT ENABLES INTUITIVE PROGRAMMING OF ROBOTS WITHOUT PRIOR KNOWLEDGE. INDUSTRIAL INNOVATION

COMPANY DETAILS LOCATION Braunschweig, Germany

ESTABLISHED YES

WEBSITE www.aeonrobotics.com

TRL TRL 5

PATENTS GRANTED 1

EMPLOYEES 3

FUNDING DETAILS FUNDING STAGE PRE-SEED

FUNDING NEEDED &,500,000 EUR

PUBLIC FUNDING 630,700 EUR

182

REVENUE 3&&,&13 EUR

The HandEffector features sensorless sub-newton force measurement, providing human-like dexterity for complex tasks. Combined with our robust AeonDrive technology, it utilizes a patented AI-based teaching method. This synergy allows for the precise automation of manual processes while eliminating traditional programming barriers.

COMPUTA

Labor shortages threaten the industry. Solutions are often too complex or expensive for dexterous tasks.

Human-like hands are the crucial interface for versatile environmental interaction. With AI-DROID we offer an affordable humanoid robot system, ensuring competitiveness and technological sovereignty through intuitive, scalable automation.

VITALA

APPROACH

STATUS The HandEffector 2 is available as industry-ready version, generating revenue as a standalone component. While scaling to a full humanoid system, we have secured patents and are successfully collaborating with pilot customers. Our focus remains on achieving human-like dexterity for industrial applications.

ALGORA

MATERIA

MOTIVATION

Sönke Michalik

FACTURA

Sören Michalik

STELLA

Lars Heim

ENERGIA

TEAM

183

BOROBOTICS BOROBOTICS IS A SPIN-OUT FROM THE UNIVERSITY OF ZURICH AND IS DEVELOPING A DRILLING ROBOT WHICH, ONCE INSTALLED, WILL BE ABLE TO DRILL BOREHOLES TO A DEPTH OF 500 METERS FULLY AUTOMATICALLY. INDUSTRIAL INNOVATION

COMPANY DETAILS LOCATION Winterthur, Switzerland

ESTABLISHED YES

WEBSITE www.borobotics.ch

TRL TRL 6

PATENTS GRANTED 2

EMPLOYEES 14

FUNDING DETAILS FUNDING STAGE PRE-SEED

FUNDING NEEDED 500,000 EUR

PUBLIC FUNDING 3,&00,000 EUR

184

PRIVATE FUNDING - EU &,600,000 EUR

Contrary to conventional drills (which require 50m2 to drill, require personnel to operate, cost 1.5M and run on diesel) we are developing a fully autonomous drilling robot that sits entirely inside of the borehole that its creating. The drill does not require any drill pipes, diesel compressor or personnel to operate and costs a fraction.

COMPUTA

Geothermal heat is the most efficient way we can heat and cool buildings, yet it is barely used due to drilling.

Drilling is too space and cost intensive. We make geothermal drilling more accessible and cost efficient, removing a major hurdle to sustainable, cheap heating and cooling.

VITALA

APPROACH

STATUS We are currently in the prototyping stage, testing different modules of the drill in the field as well as the lab. We have drilled down to a depth of 30 meters. The next milestones are to reach 50 meters of depth as well as test our borehole structural support module in the field inside the full MVP.

ALGORA

MATERIA

MOTIVATION

Philipp Ganz

FACTURA

Moritz Pill

STELLA

Hans-Jörg Denning

ENERGIA

TEAM

185

CONTINUUM INNOVATION JOIN THE ROBOT REVOLUTION. INDUSTRIAL INNOVATION

COMPANY DETAILS LOCATION Berlin, Germany

ESTABLISHED YES

TRL TRL 6

EMPLOYEES 6

WEBSITE www.continuum-innovation.de

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED 5,000,000 EUR

186

REVENUE &50,000 EUR

Continuum Innovation is developing a scalable soft cobot platform with continuous mechanics that fundamentally changes the areas of application for robotic arms and interaction with them. The robotic arm, which moves like an elephant‘s trunk, can operate in confined spaces and is much more flexible than conventional robots, thereby increasing efficient.

COMPUTA

The vision is a universal, scalable automation platform that enables safe and accessible automation of manual work in all areas of life and work.

VITALA

APPROACH

MATERIA

MOTIVATION

STATUS

ALGORA

MVP Status is reached, pilot tests have started.

One SME in Berlin with cobot focus. One with Siemens Energy with inspection focus.

TEAM

STELLA

FACTURA

ENERGIA

Kilian Reiß

187

ENADYNE THE NEXT GENERATION IN CHEMICAL TECHNOLOGY AND EMISSION ABATEMENT. INDUSTRIAL INNOVATION

COMPANY DETAILS LOCATION Leipzig, Germany

ESTABLISHED YES

WEBSITE www.enaDyne.com

TRL TRL 4

PATENTS GRANTED 3

EMPLOYEES 36

FUNDING DETAILS FUNDING STAGE SERIES A

FUNDING NEEDED 1-,500,000 EUR

REVENUE 1,700,000 EUR

PRIVATE FUNDING 3,400,000 EUR

PRIVATE FUNDING - EU 5,100,000 EUR

PUBLIC FUNDING 4-,000,000 EUR

188

enaDyne‘s Non-Thermal Plasma Catalysis platform activates molecules electrically - no combustion, no fossil fuel, no waste. Pulsed fields drive reactions at near-ambient temperature on proprietary ceramic electrodes with integrated catalysts.

Same hardware for abatement, splitting, and synthesis. Scales modularly from single unit to container fleet

COMPUTA

Industrial chemistry runs on centuryold thermal processes - fossil-fired, inefficient, inflexible. They cannot electrify, use renewables, or decouple from fossil feedstocks. enaDyne replaces them with a fully electric, modular platform - from semiconductor abatement to industrial-scale chemical synthesis, built on one core technology.

VITALA

APPROACH

STATUS EUR 1.7M revenue from joint development, prototypes & test infrastructure. EUR 20M Take-or-Pay in final negotiation with leading semicon abatement OEM. LOI with Fortune 500 chemical company, MOU with global catalysis leader. EUR 7M seed closed. ~EUR 4.5M grants. Team of ~40. SPRIND Carbon-to-Value winner, Hello Tomorrow & Sächsischer Gründerpreis.

ALGORA

MATERIA

MOTIVATION

TEAM

FACTURA

ENERGIA

Christian Koch

STELLA

Philipp Hahn

189

FLUIDECT WITH SPHEROSCAN, FLUIDECT IS ENABLING A BREAKTHROUGH IN THE DIGITIZATION OF BIOPROCESSES. USING ITS TECHNOLOGY, FLUIDECT DETECTS BACTERIA AND PATHOGENS DIRECTLY IN THE MEDIUM IN SECONDS. INDUSTRIAL INNOVATION

COMPANY DETAILS LOCATION Jena, Germany

ESTABLISHED YES

WEBSITE www.fluidect.com

TRL TRL 6

PATENTS GRANTED 5

EMPLOYEES 19

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED 5,000,000 EUR

PRIVATE FUNDING - EU &,000,000 EUR

PUBLIC FUNDING 5,000,000 EUR

190

REVENUE 1,&00,000 EUR

Our solution uses microscopic biosensors that freely float in the process liquid and selectively bind target proteins or microorganisms.

Their Fluorescent Resonator Signature (FRS) is read out optically, enabling rapid, label-free and multiplex quantification. Automated sampling allows seamless at-line and fully online deployment.

COMPUTA

Our vision is to digitize bioprocesses end-to-end. With our FRS sensor platform, we bring lab-grade bioanalytics directly into industrial production in real time. This enables safer food, higher yields, less waste, and true Industry 4.0 control of biological systems.

VITALA

APPROACH

STATUS We developed and validated the patented FRS biosensor platform, delivered the first SpheroScan Explorer systems to paying pilot customers, and generated €1m+ revenue with €1m in orders. Our impact is recognized by major awards including the SPIE Prism Award and the German Food Startup Award.

ALGORA

MATERIA

MOTIVATION

FACTURA

Michael Himmelhaus

STELLA

Tobias Schröter

ENERGIA

TEAM

191

HUMIFY HUMIFY TRANSFORMS BIOMASS INTO ARTIFICIAL HUMIC SUBSTANCES – RESTORING FERTILE SOILS, BOOSTING CARBON CAPTURE, AND SCALING SOLUTIONS FOR CLIMATE AND FOOD SECURITY. INDUSTRIAL INNOVATION

COMPANY DETAILS LOCATION Teltow, Germany

ESTABLISHED YES

FUNDING DETAILS FUNDING STAGE SEED

192

WEBSITE www.humify.earth

The continuous hydrothermal humification process developed by Humify is patented and can convert a variety of biomass into artificial humic substances. At the same time carbon and key nutrients such as phosphorus and nitrogen are preserved.

Through the microbial activation of humus, we achieve an amplification effect on carbon sequestration in soil.

COMPUTA

Essential topsoil is lost at rates far greater than it can be replaced naturally. To restore soil and its ability to capture and store carbon, organic matter (humus) must be replaced from an external source. Humify’s HTH-process provides the unique opportunity to replenish the amount of humus required for healthy soil -much faster than the natural.

VITALA

APPROACH

STATUS patent filed (process and product); additional claims being prepared; product: TRL 6; batch process HTH: TRL 7 continuous process HTH: TRL 4 pot & field tests with various crops in multiple climates; independent plant tests

by HU Berlin; Horizon Europe project; SPRIND validation project; funding round with Business Angels (2025); preparing next

ALGORA

MATERIA

MOTIVATION

TEAM

STELLA

FACTURA

ENERGIA

Svitlana Filonenko

193

ILLUTHERM WE DECARBONIZE INDUSTRIAL HEAT AT REDUCED ENERGY COST. INDUSTRIAL INNOVATION

COMPANY DETAILS LOCATION Darmstadt, Germany

ESTABLISHED YES

WEBSITE www.illutherm.com

TRL TRL 6

PATENTS GRANTED 7 (applications)

EMPLOYEES 12

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED 7,000,000 EUR

PRIVATE FUNDING - EU 1,700,000 EUR

PUBLIC FUNDING 1,300,000 EUR

194

REVENUE 100,000 EUR

We are pionieers in LED-based industrial heat decarbonizing industrial heat and accelerating heating processes >10x.

We build the world strongest LEDs.

COMPUTA

APPROACH

MATERIA

VITALA

MOTIVATION

STATUS

ALGORA

Seed stage working on product-market fit with several paid proof-of-concept projects completed.

Michael Scherer

FACTURA

Milto Vlachos

STELLA

Lukas Porz

ENERGIA

TEAM

195

INFRASONIK SHAPING THE FUTURE OF INDUSTRY WITH INFRASOUND TECHNOLOGY. INDUSTRIAL INNOVATION

COMPANY DETAILS LOCATION Spanga, Sweden

ESTABLISHED YES

TRL TRL 7

EMPLOYEES 7

WEBSITE www.infrasonik.se

FUNDING DETAILS FUNDING STAGE PRE-SEED

FUNDING NEEDED 1,000,000 EUR

196

REVENUE %60,000 EUR

Infrasonik develop technologies based on high-intensity infrasound to actively enhance heat and mass transfer. By generating strong oscillatory flows, we increase transport rates and enable faster, more uniform cooling and drying within existing industrial processes and equipment.

COMPUTA

Industry lacks efficient and controllable methods for cooling and drying in metal processing and industrial production. This leads to high energy use, uneven quality, and complex processes, affecting energy-intensive sectors such as steel and bio-based industries.

VITALA

APPROACH

STATUS InfraCooler: validated in lab environments with partners including SSAB and Industeel, and in industrial environment with Gestamp. Ongoing work focuses on FOAK. InfraDryer: existing full scale pilot, now focus on first sales and scaling

ALGORA

MATERIA

MOTIVATION

TEAM

FACTURA

ENERGIA

Winston Olsson

STELLA

Helen Mattsson

197

MAGNOTHERM REFRIGERANT-FREE COOLING – MAGNOTHERM DEVELOPS MAGNETIC COOLING TECHNOLOGY BASED ON THE MAGNETOCALORIC EFFECT. INDUSTRIAL INNOVATION

COMPANY DETAILS LOCATION Darmstadt, Germany

ESTABLISHED YES

WEBSITE www.magnotherm.com

TRL TRL 7

PATENTS GRANTED 10

EMPLOYEES 30

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED 15,000,000 EUR

REVENUE &00,000 EUR

PRIVATE FUNDING 100,000 EUR

PRIVATE FUNDING - EU 7,300,000 EUR

PUBLIC FUNDING 7,500,000 EUR

198

Experts in magnetocaloric materials, magnets, and system engineering, we lead the shift to refrigerant-free cooling. Deeply embedded across the value chain, we build core IP and know-how, partnering with OEMs to drive adoption and set future standards for cooling across retail, data centres, HVAC, manufacturing, and beyond.

COMPUTA

Europe pioneered refrigeration with Carl von Linde. Now a critical part of modern infrastructure, legacy systems have become an efficiency and climate burden. Magnetic cooling offers a paradigm shift: higher efficiency, no harmful refrigerants, and a path to renewed technology sovereignty with climate-positive profitability.

VITALA

APPROACH

STATUS Magnetic cooling is de-risked, with devices sold and deployed globally for testing, showcasing, and food and beverage retail. Key commercial partners include Coca-Cola, AB InBev, and REWE Group, with a supermarket pilot planned for 2026. Scaling is underway with an established supply chain, ready for widespread adoption.

ALGORA

MATERIA

MOTIVATION

TEAM

FACTURA

ENERGIA

Timur Sirman

STELLA

Maximilian Fries

199

MICROBUBBLES MICROBUBBLES REMOVES MICROPLASTICS AND MICROPOLLUTANTS FROM SURFACE WATER PHYSICALLY – EFFICIENT, CHEMICAL-FREE, AND SUSTAINABLE USING PATENTED MICROBUBBLE TECHNOLOGY. INDUSTRIAL INNOVATION

COMPANY DETAILS LOCATION Leipzig, Germany

EMPLOYEES 32

ESTABLISHED YES

FUNDING DETAILS FUNDING STAGE PRE-SEED

200

WEBSITE www.microbubbles.org

We develop and scale in-situ microflotation to remove microplastics and micropollutants from contaminated water. Our microflotation system is already being used to sustainably reduce filterable substances (TSS and TSS63), microplastics and micropollutants from surface-water and wastewater.

COMPUTA

Since 1950, over 10.9 billion tons of plastics have been produced worldwide, of which around 21 millions tons end up in our oceans every year.

Our goal: to detect microplastics and pollutants at an early stage, remove them effectively, and thus ensure the long-term protection of our waters.

VITALA

APPROACH

MATERIA

MOTIVATION

STATUS

ALGORA

We have a number of reference projects that are being scientifically monitored and have already resulted in publications validating the performance and capabilities of our in-situ microflotation system.

TEAM

FACTURA

ENERGIA

Christian Henning

STELLA

Roland Damann

201

MUNIQO PERFORMANTE ENGINEERING THE FUTURE OF VIBRATION CONTROL AND ISOLATION TECHNIQUES. INDUSTRIAL INNOVATION

COMPANY DETAILS LOCATION Munich, Germany

ESTABLISHED YES

TRL TRL 5

EMPLOYEES 6

WEBSITE www.muniqoperformante.com

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED 700,000 EUR

202

PUBLIC FUNDING 3&0,000 EUR

Our anti-vibration technology is designed as a scalable platform. Beyond the initial medical transport application, we expand with a vibration measurement box and passive shock absorbers, enabling rapid scaling into adult patient transport and other industries requiring advanced vibration protection.

COMPUTA

Our vision is to become the leading player in vibration compensation and establish ourselves as a category-defining technology company in this field. While patient transport is our initial focus, the underlying technology has clear applications far beyond healthcare, including microscopy, quantum technology and advanced industrial precision systems.

VITALA

APPROACH

STATUS We have fully validated patient transport as our initial use case, and we are currently in the final stage of testing the technology in real world. With the support of SPRIND, we are testing the system under extreme conditions to determine its technological limits and transfer potential. In next few weeks we apply for public funding (KMU, IEC)

ALGORA

MATERIA

MOTIVATION

TEAM

FACTURA

ENERGIA

Luca Fabiano

STELLA

Sebastian Wann

203

POLYBOT POLYBOT CREATES A PORTABLE EDGE ROBOTICS PLATFORM FOR AGRICULTURE – SMALL, VERSATILE ROBOTS FOR HARVESTING, WEEDING, AND DRIVING THE SHIFT FROM MONOCULTURES TO BIODIVERSE FARMING. INDUSTRIAL INNOVATION

COMPANY DETAILS LOCATION Tuebingen, Germany

ESTABLISHED YES

TRL TRL 5

EMPLOYEES 7

WEBSITE www.polybot.eu

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED 1,%00,000 EUR

204

PRIVATE FUNDING - EU 30,000 EUR

We start with a market that needs this solution today: high-value crops in greenhouses, where labor costs are high and labor is hard to find. Our robots learn picking end-to-end from humans, a radically data-driven approach that adapts fast to new tasks and new crops in the greenhouse and beyond. From there toward resilient, diversified farming.

COMPUTA

Monocultures are efficient but unsustainable: degrading biodiversity, losing harvests to climate extremes.

The alternatives are diverse, resilient polycultures, but in order to be economical they need automation as dexterous as humans. Our goal: future proofing humanities food production.

VITALA

APPROACH

STATUS We started the lab development in January 2025, autonomously picked our first tomato in a greenhouse in May, and harvested full rows reliably in December.

We work closely with growers and are on course to run a completely integrated operational pilot in summer 2026 and the first system deliveries in early 2027.

ALGORA

MATERIA

MOTIVATION

Claudio Michaelis

Elias Atahi

FACTURA

Maike Kaufmann

STELLA

Martin Kiefel

ENERGIA

TEAM

205

SOURCELIGHT A DIVISION OF FOCUSED ENERGY MAKING THE INVISIBLE VISIBLE0 COMPACT LASER-DRIVEN X-RAY AND NEUTRON SOURCES FOR NEXT-GENERATION NON-DESTRUCTIVE TESTING. INDUSTRIAL INNOVATION

COMPANY DETAILS LOCATION Berlin, Germany

ESTABLISHED NO

WEBSITE www.sourcelight.co

TRL TRL 4

PATENTS GRANTED 3

EMPLOYEES 20

FUNDING DETAILS FUNDING STAGE SERIES A

FUNDING NEEDED &5,000,000 EUR

206

SourceLight develops compact, laser-driven radiation sources generating synchronized MeV X-rays and neutrons, based on Focused Energy’s inertial fusion approach. This enables high-resolution imaging and direct material identification in a modular system, combining advanced physics with AI-driven analysis for real-time inspection.

COMPUTA

Critical industries such as nuclear waste, security, and defense lack reliable methods to inspect complex or shielded materials. This leads to uncertainty, safety risks, and high false positives. A new inspection capability is needed to enable direct material understanding and reduce operational and regulatory constraints.

VITALA

APPROACH

STATUS SourceLight is in an advanced development phase, with core technology validated at TRL 4–5 and system architecture defined. The prototype facility (PLANET) is under construction in Biblis. Current focus is on system integration, performance optimization, and preparation of first pilot applications with industrial partners.

ALGORA

MATERIA

MOTIVATION

TEAM

FACTURA

ENERGIA

Patrik Karwat

STELLA

Sebastian Wojczik

207

SYMBIOTIC GREEN TECHNOLOGIES A NEW GENERATION OF INDUSTRIALSCALE FOOD PRODUCTION AND RESILIENT PLANT-BASED RAWMATERIAL SUPPLY TECHNOLOGY. INDUSTRIAL INNOVATION

COMPANY DETAILS LOCATION Gernsheim, Germany

ESTABLISHED YES

TRL TRL 7

EMPLOYEES 5

WEBSITE www.symbiotic-gt.com

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED &,000,000 EUR

PUBLIC FUNDING 40,000 EUR

208

PRIVATE FUNDING - EU 711,000 EUR

SymBiotic Green Technologies is redefining vertical farming with Gravity Farming, a novel cultivation system that actively leverages plant gravitropism to stimulate growth. Combined with an automated conveyor-based cultivation and central harvesting system, it drastically reduces labor costs and enables true industrialscale operations.

COMPUTA

Food production is constrained by climate change, limited land, and rising costs. SymBiotic’s Gravity Farming technology industrializes crop production through automation, AI, and higher plant density—enabling scalable, reliable, and resource-efficient food production anywhere.

VITALA

APPROACH

STATUS SymBiotic has developed its Gravity Farming technology and system architecture and is advancing an AI-driven plant monitoring platform. The company is preparing pilot deployments and engaging with strategic partners and investors to bring the first Gravity Farm systems to market.

ALGORA

MATERIA

MOTIVATION

Fabio La Manna

FACTURA

Andreas Zillinger

STELLA

Alexander Zillinger

ENERGIA

TEAM

209

WELDNOVA A FUNDAMENTALLY NEW MANUFACTURING TECHNOLOGY CONTROLS MOLTEN METAL WITH MAGNETIC FIELDS, ENABLING 10X FASTER, CHEAPER, AND MORE RELIABLE PRODUCTION ACROSS HEAVY INDUSTRY. INDUSTRIAL INNOVATION

COMPANY DETAILS LOCATION Berlin, Germany

ESTABLISHED YES

WEBSITE www.weldnova.com

TRL TRL 6

PATENTS GRANTED 1

EMPLOYEES 6

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED 1,%00,000 EUR

PRIVATE FUNDING - EU 50,000 EUR

PUBLIC FUNDING 1,157,%0- EUR

210

REVENUE 163,3%4 EUR

Controlled magnetic fields actively manipulate molten weld pools on the fly. This stabilises the melt against gravity, enabling single-pass welding of thick metals. The modular hardware retrofits existing systems and is being expanded into a platform technology for metallic material processing. We scale via industrial pilots and partnerships.

COMPUTA

Industrial welding of thick metal still relies on multi-pass, 90-year-old processes. Heavy industries such as wind, shipbuilding, infrastructure or chemical industry suffer from high costs, long lead times, labor shortages and logistical limits. Solving this bottleneck is critical for industrial competitiveness, scalability and resilience.

VITALA

APPROACH

STATUS Currently active in paid PoC and qualification and certification projects with customers from various industries. Reached TRL6 in core technology, supported by 10+ years of applied research. Alpha and beta systems are operational, validated in industrial pilots with OEMs and SMEs and third-partys. Supported by five patent applications.

ALGORA

MATERIA

MOTIVATION

Ömer Üstünda5

Christian Brunner-Schwer

FACTURA

Nasim Bakir

STELLA

Fatma Akyel

ENERGIA

TEAM

211

AETOSPHERE AETOSPHERE DELIVERS AUTONOMOUS, SCALABLE DRONE DEFENCE FOR EUROPE, USING DISTRIBUTED RADAR, INTELLIGENT THREAT CLASSIFICATION, AND SAFE INTERCEPTOR DRONES TO STOP UNAUTHORIZED UAVS AND PROTECT AIRSPACE. AEROSPACE & RESILIENCE

COMPANY DETAILS LOCATION Warngau, Germany

ESTABLISHED YES

WEBSITE

TRL TRL 6

PATENTS GRANTED 1

EMPLOYEES 7

FUNDING DETAILS FUNDING NEEDED &,000,000 EUR

212

www.hybrid-aerospace.com

The interceptor UAV Greif uses our patented claw mechanism to capture uncooperative drones. It has a focus on mitigation of ground risk, destruction-free capture, low cost, and minimal logistic footprint.

Xneural uses distributed imaging radar, advanced signal processing, cloud computing, and AI to provide a robust wide-area detection capability.

COMPUTA

In the Aetosphere project, we combine the safe soft-capture interceptor drones from Hybrid Aerospace with a scalable distributed radar sensor network from Xneural. Together, the solution addresses the protection needs against lower end aerial threats that thousands of critical installations throughout Europe are exposed to daily.

VITALA

APPROACH

STATUS We have successfully demonstrated the Greif interceptor to multiple military and police units. We received orders for several hundred thousand Euro for orders of Greif and other effectors, with the first units already delivered and paid.

We use the SPRIND project as an opportunity to increase automation and integration into sensor networks.

ALGORA

MATERIA

MOTIVATION

TEAM

STELLA

FACTURA

ENERGIA

Michael Heinrich

213

AVIENTUS RADNAV SUPERIOR DRONE TECHNOLOGY FOR DUAL USE LOGISTICS - COST EFFICIENT, SCALABLE & HIGH PAYLOAD. AEROSPACE & RESILIENCE

COMPANY DETAILS LOCATION Zurich, Switzerland

ESTABLISHED YES

TRL TRL 5

EMPLOYEES 12

WEBSITE www.avientus.ch

FUNDING DETAILS FUNDING STAGE PRE-SEED

FUNDING NEEDED 3,3&5,000 EUR

PRIVATE FUNDING - EU 515,000 EUR

PUBLIC FUNDING 130,000 EUR

214

REVENUE 40,000 EUR

The ETH Spin Off Avientus uses a unique, patent pending concept to deliver up to 25kg directly to remote units, enabling fast, safe, and fully autonomous transport in contested environments. It uses fixed wing drones with only two motors and underslung payload, inceasing range and speed (100km, 120kph) while reducing complexity, costs and noise.

COMPUTA

To provide soldiers at the front line with supplies, e.g. food, blood, ammunition, drones are already in use.

The existing solutions suffer from inefficient concepts, leading to: a) low range (20 km), => supply posts are close to enemy fire, b) high noise and c) low speed (max. 80 kph), i.e. easy to shoot down. They also lack autonomy.

VITALA

APPROACH

STATUS Biggest achievement is the sale of one prototype to the Swiss army. LoIs and requests for testing exist from Ukraine (3 different units) and the Bundeswehr, as well as for pilot projects from two civilian companies. We are invited to a NATO exercise in autumn 26. Achieving stage 2 of SPRIND „fully autonomous flight 2.0“ proves technical traction.

ALGORA

MATERIA

MOTIVATION

Alex Hönger

FACTURA

Johannes Aicher

STELLA

Pascal Schoppmann

ENERGIA

TEAM

215

CDDS SECURING SKIES, SAVING LIVES. AEROSPACE & RESILIENCE

COMPANY DETAILS LOCATION Schlieren, Switzerland

EMPLOYEES 12

ESTABLISHED YES

FUNDING DETAILS FUNDING STAGE SEED

216

WEBSITE www.cdds.ai

The CDDS interceptor is an autonomous, kinetic counter drone designed to neutralize Group 1 and Group 2 Unmanned Aerial System (UAS) threats with speed and precision.

Powered by onboard AI and real-time decision making, each interceptor detects, tracks, and neutralizes hostile threats independently.

COMPUTA

We stop hostile drones before they cause harm. Using autonomous kinetic interceptors, CDDS delivers scalable counter-drone defense with minimal collateral impact: Effective against highly maneuverable drone swarms.

VITALA

APPROACH

MATERIA

MOTIVATION

STATUS

ALGORA

CDDS is showcasing its capabilities worldwide, positioning itself amng leading companies in fully autonomous, AI-driven drone piloting, making AI-pilots accessible for low-cost aircraft.

TEAM

FACTURA

ENERGIA

David Shapira

STELLA

Christoph Bertschi

217

GETWING GETWING WORKS ON REDUCING DRAG AND INCREASING EFFICIENCY THROUGH BLENDED WING BODY DESIGN – ENABLING THE NEXT GENERATION OF SUSTAINABLE AIRCRAFT AND UAVS. AEROSPACE & RESILIENCE

COMPANY DETAILS LOCATION Hamburg, Germany

ESTABLISHED YES

TRL TRL 6

EMPLOYEES 3

FUNDING DETAILS FUNDING STAGE SEED

REVENUE &30,000 EUR

218

WEBSITE www.getwing.com

GETWING develops blended wing aircraft where the entire body generates lift, cutting drag by over 30%. Using efficient engines and smart configurations, we enable one platform to serve both long-haul and short-haul missions with superior performance.

COMPUTA

GETWING aims to make aviation more efficient, comfortable and accessible. By reducing drag by over 30%, we unlock new routes and business models, enabling airlines to fly farther with less energy and bring direct, sustainable travel to more people worldwide.

VITALA

APPROACH

MATERIA

MOTIVATION

STATUS

ALGORA

We have a manned flying prototype demonstrating efficiency, stability and safety and are now entering our seed round raising capital to build and validate our next demonstrator.

Marko Stamenovic

FACTURA

Filip Piskorzynski

STELLA

Bernhard Mattlener

ENERGIA

TEAM

219

HYPERSONICA BUILDING EUROPE’S HYPERSONIC PRIME. AEROSPACE & RESILIENCE

COMPANY DETAILS LOCATION Munich, Germany

ESTABLISHED YES

TRL TRL 4

EMPLOYEES 47

WEBSITE www.hypersonica.com

FUNDING DETAILS FUNDING STAGE SERIES A

PRIVATE FUNDING &3,000,000 EUR

PUBLIC FUNDING &50,000 EUR

220

PRIVATE FUNDING - EU 3,000,000 EUR

Hypersonica positions itself as an agile player at the interface of research, industrial development and strategic technology partnership. Its core competence of „manoeuvrable hypersonic flight“ will be used both in a military context for hypersonic missiles, and in the civil use of space in the form of manoeuvrable re-entry into the atmosphere.

COMPUTA

The Anglo-German company Hypersonica was founded by Dr. Philipp Kerth and Dr. Marc Ewenz to equip Europe with the sovereign, technological edge it needs to deter military aggression and uphold freedom & independence in a more dangerous world.

VITALA

APPROACH

STATUS Hypersonica GmbH is a growing technology company focusing on the hypersonic sector. The company was founded on 23rd November 2023 and received VC investments by e.g., Plural Platform, General Catalyst and SPRIND. With currently 47 employees based in Germany and the UK, it rapidly scales its capabilities.

ALGORA

MATERIA

MOTIVATION

Dustin Büttner

Felix Braun

FACTURA

Philipp Kerth

STELLA

Marc Ewenz

ENERGIA

TEAM

221

NEUROSPACE WORLD‘S FIRST MODULAR ROVER PLATFORM - MADE IN GERMANY. AEROSPACE & RESILIENCE

COMPANY DETAILS LOCATION Berlin, Germany

ESTABLISHED YES

TRL TRL 9

EMPLOYEES 14

WEBSITE www.neuro-space.de

FUNDING DETAILS FUNDING STAGE SEED

FUNDING NEEDED 3,000,000 EUR

PRIVATE FUNDING - EU 1,450,000 EUR

PUBLIC FUNDING 1,700,000 EUR

222

REVENUE 60,000 EUR

HiveR provides a unified hardware and software platform for rovers and small satellites operating across Earth, orbit, and the Moon. Using modular architecture, shared avionics, and standardized communication protocols, HiveR reduces development time, lowers mission costs, and enables scalable deployment of space systems.

COMPUTA

Earth. Orbit. Moon. As technology expands from Earth to orbit and the Moon, the lack of standardized infrastructure slows innovation. HiveR - one platform solving three problems by providing a unified technology for rovers and small satellites, that saves time, reduces costs, and enables scalable space operations.

VITALA

APPROACH

STATUS NEUROSPACE developed TACHELES, a deep-space satellite built under NASA requirements and selected for the Artemis II mission. We are building HiveR, a modular robotics and satellite platform for Earth, orbit, and lunar missions, with early industry customers and ongoing commercial discussions.

ALGORA

MATERIA

MOTIVATION

TEAM

FACTURA

ENERGIA

Margarita Trubizin

STELLA

Irene Selvanathan

223

NEWORBIT SPACE NEWORBIT IS ENGINEERING THE LOWEST-ORBITING SATELLITES ON EARTH TO RAPIDLY ADVANCE GLOBAL CONNECTIVITY AND INSIGHTS. AEROSPACE & RESILIENCE

COMPANY DETAILS LOCATION Reading, England

ESTABLISHED YES

WEBSITE www.neworbit.space

TRL TRL 6

PATENTS GRANTED 3

EMPLOYEES 31

FUNDING DETAILS FUNDING STAGE SERIES A

PRIVATE FUNDING - EU &7,600,000 EUR

224

We‘re about to launch our first satellite, carrying 3-4 payloads within Earth observation. The goal of the first mission is to validate the first commercially available European VLEO platform and demonstrate the performance advantages of VLEO.

COMPUTA

Engineering Earth‘s Lowest Orbiting Satellites.

VITALA

APPROACH

MATERIA

MOTIVATION

STATUS

ALGORA

We‘re currently pursuing a validation contract with SPRIND to examine the breakthrough potential of VLEO.

Ruslan Rakhimov

FACTURA

Alexander Kiermeier

STELLA

Anatolii Papulov

ENERGIA

TEAM

225

NOUMA AUTONOMY ONE BRAIN. ANY BODY. NOUMA CORTEX TURNS UNMANNED SYSTEMS INTO AUTONOMOUS AGENTS THAT SEE, REASON, AND ACT, WITHOUT GPS, CLOUD, OR REMOTE CONTROL. AEROSPACE & RESILIENCE

COMPANY DETAILS LOCATION Nuremberg, Germany

ESTABLISHED YES

TRL TRL 5

EMPLOYEES 4

FUNDING DETAILS FUNDING STAGE PRE-SEED

FUNDING NEEDED 750,000 EUR

226

WEBSITE www.nouma-autonomy.de

NOUMA develops Cortex, a visionlanguage model based software stack enabling unmanned systems to be briefed in natural language and make onboard decisions in real time. Runs entirely on edge hardware without GPS or cloud dependency, combining visual scene understanding and mission reasoning.

COMPUTA

Critical missions in search and rescue, disaster response, and defense require unmanned systems that operate where GPS, communications, and human oversight fail. Today‘s drones are remote-controlled tools that stop working when connectivity drops. Lives depend on closing this gap.

VITALA

APPROACH

STATUS Founded in February 2026 as a spin-off from Friedrich-Alexander-Universität Erlangen-Nürnberg. Already running the software stack on multiple embodiments across domains. Preparing for the live demonstration final of the SPRIND Funke „Fully Autonomous Flight 2.0“ in late summer 2026.

ALGORA

MATERIA

MOTIVATION

Andreas Gründer

Sebastian Reitelshöfer

FACTURA

Christopher May

STELLA

Leon Seidel

ENERGIA

TEAM

227

POLARIS HORIZONTAL TAKE-OFF SPACEPLANES FOR ECONOMIC, FLEXIBLE AND SAFE ACCESS TO SPACE AND FOR HYPERSONIC MISSIONS. AEROSPACE & RESILIENCE

COMPANY DETAILS LOCATION Bremen, Germany

ESTABLISHED YES

EMPLOYEES 90

FUNDING DETAILS FUNDING STAGE SEED

228

WEBSITE www.polaris-raumflugzeuge.de

We follow a strongly iterative approach with designing, building and flying scaled spaceplane demonstrators with high pace. Each new vehicle becomes larger and more performant than the previous one. By this iterative approach, we gain strong practical experience within short time and de-risk technology already in early project phases.

COMPUTA

POLARIS aims on revolutionizing spaceflight by creating an aircraftlike access to space. Our reusable horizontal take-off spaceplanes will provide a unique combination of superior economic viability, flexibility, safety and sustainability. Our ultimate vision is to establish an airline to space for routine transport of passengers and cargo.

VITALA

APPROACH

STATUS We have built and flown already seven scaled demonstrators with more than 250 flights, and are currently building the next four vehicles. In addition, we have developed a novel type of rocket engines, so-called linear aerospikes. A 1 kN engine was successfully flight-tested - a world premiere, while a 20 kN follow-on engine is in development.

ALGORA

MATERIA

MOTIVATION

TEAM

STELLA

FACTURA

ENERGIA

Alexander Kopp

229

UBASWARM AUTONX UNIFIES UAV DATA AND CONTROL WITH A WIDGET-BASED UI SO OPERATORS FOCUS ON MISSIONS, NOT INFRASTRUCTURE. AEROSPACE & RESILIENCE

COMPANY DETAILS LOCATION Berlin, Germany

ESTABLISHED YES

TRL TRL 6

EMPLOYEES 3

FUNDING DETAILS FUNDING STAGE PRE-SEED

230

WEBSITE www.autonx.de

We bridge the gap with vehicle-specific modules that translate various drone SDKs into a unified format.

Via encrypted VPNs, we provide a browser-based, widget-driven UI for real-time swarm control and data introspection on any device, including VR. Integrated with ROS2 and open APIs, our ecosystem lets developers automate the „annoying part.“

COMPUTA

UAV operations are crippled by reinventing the wheel syndrome.

Developers waste months on basic telemetry and UI instead of missioncritical tasks, often relying on unstable, makeshift solutions. We provide the unified ecosystem for drone OEMs and operators to manage data streams and swarms, enabling them to focus on innovation, not infrastructure.

VITALA

APPROACH

STATUS As a TU Berlin spin-off, we are validating our ecosystem in the Fully Autonomous Flight Challenge, solving GNSS-denied navigation. Led by a swarm navigation PhD and aviation experts, we have initiated pilot-focused dialogues with industry peers to refine product-market fit and are currently formalizing our business model for market entry.

ALGORA

MATERIA

MOTIVATION

Bastian Göbel

Fabian Frickenstein

FACTURA

Anne-Sophie Polz

STELLA

Mats Martens

ENERGIA

TEAM

231

ZETATOR ZETATOR DEVELOPS AI-DRIVEN TECHNOLOGIES FOR SPACE EXPLORATION, ENABLING THE CISLUNAR FRONTIER, AUTONOMY, AND HABITABLE SYSTEMS BEYOND EARTH. AEROSPACE & RESILIENCE

COMPANY DETAILS LOCATION Trier, Germany

ESTABLISHED YES

TRL TRL 4

EMPLOYEES 4

FUNDING DETAILS FUNDING STAGE PRE-SEED

FUNDING NEEDED 10,000,000 EUR

232

WEBSITE www.zetator.com

Zetator will design, build, and deploy a satellite to detect and track spacecraft beyond Earth orbit in cislunar space. Using advanced sensors, onboard AI analysis, and optical/ RF communications, we will deliver space domain awareness. We partner with other for spacecraft, ground systems, and operations to realize a scalable architecture.

COMPUTA

Cislunar space is rapidly becoming contested and congested, yet remains largely invisible. Without the ability to detect and understand activity beyond Earth orbit, governments, industry, and missions operate blind, thus creating risks to security, safety, and the future of space itself.

VITALA

APPROACH

STATUS We have developed a prototype space domain awareness system using AI to detect anomalies in Earth orbiting objects. It extends to modeling objects in cislunar space, where no data yet exists. We are now conducting funded research to define validate the technical approach, with future system development as a separate step.

ALGORA

MATERIA

MOTIVATION

TEAM

FACTURA

ENERGIA

S. Peter Worden

STELLA

Randall Correll

233

IMPRESSUM Booklet zum Event ‚VENTURE SPRIND 2026‘ Veröffentlicht am: 14. April 2026, Leipzig (Deutschland) Verfasser: SPRIND GmbH Lagerhofstr. 4 04103 Leipzig info@sprind.org Geschäftsführung: Berit Dannenberg Rafael Laguna de la Vera Vorsitzender des Aufsichtsrats: Dr.-Ing. E. h. Peter Leibinger Handelsregister: Amtsgericht Leipzig (HRB 36977) Umsatzsteuer-Identifikationsnummer nach § 27a Umsatzsteuergesetz DE328253854 INHALT DER TEAMSEITEN: Die dargestellten Unternehmen tragen die alleinige Verantwortung für den Inhalt der Team-Seiten.

KONZEPT UND DESIGN: SPRIND GmbH BILDNACHWEIS: Die Personenbilder und Teamlogos in diesem Booklet wurden von den entsprechenden Unternehmen zur Nutzung im Rahmen des Events ‚VENTURE SPRIND 2026‘ am 14. April 2026 bereitgestellt. Alle anderen Abbildungen und Fotos sind Eigentum der SPRIND GmbH.