RNA - Structure and function II

Molecular Pathology

Molecular Biology Principles

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Molecular Pathology

Molecular Biology Principles

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Molecular Pathology

Molecular Biology Principles

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Molecular Pathology

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Visualization of heterogeneous ribonulceoprotein particle (hnRNP) protein ! associated with nascent transcripts!

Molecular Biology Principles

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Molecular Pathology

Molecular Biology Principles

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Molecular Pathology

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Consensus sequences around 5 and 3 splice sites in vertebrate pre-mRNA!

Molecular Biology Principles

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Molecular Pathology

Molecular Biology Principles

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Molecular Pathology

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DNA: blue!

Polyadenylated RNA: red!

Molecular Biology Principles

Splicing protein: green!

Polyadenylated RNA: red!

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Molecular Pathology

Molecular Biology Principles

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Molecular Pathology

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The nuclear pore complex!

Molecular Biology Principles

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Molecular Pathology

Molecular Biology Principles

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Molecular Pathology

Molecular Biology Principles

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Molecular Pathology

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A mammalian example!

Molecular Biology Principles

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Molecular Pathology

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Iron-dependent regulation of the stability of transferrin-receptor mRNA!

Molecular Biology Principles

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Molecular Pathology

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Iron-dependent regulation of translation of ferritin mRNA!

Molecular Biology Principles

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Molecular Pathology

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Introduction of a pre-rRNA transgene induces formation of a new nucleolus!

Molecular Biology Principles

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Molecular Pathology

Molecular Biology Principles

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Molecular Pathology

Molecular Biology Principles

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