Essen%al Dermatopathology
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Essen%al Dermatopathology
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Skin specimen Inflammatory conditions
With epidermal alteration
Proliferative/ neoplastic conditions
Without epidermal alteration
Epidermal
Non-inflammatory conditions
"Normal skin"
Dermal and subcutis
Characterization of dermal/subcutaneous inflammatory process
Inflammatory Conditions with Epidermal Alteration Psoriasiform dermatitis
Interface dermatitis
Spongiotic dermatitis
Lichenoid type
Conventional
Vacuolar type
Eosinophilic
Follicular
Vesicobullous conditions Intraepidermal
Subepidermal
Subcorneal
Junctional
Stratum spinosum
Dermolytic
Suprabasilar Miliarial
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Essen%al Dermatopathology
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Inflammatory conditions without epidermal alterations Dermal/subcutaneous inflammatory process
Perivascular dermatitis With vacular damage
Vasculopathy
Nodular dermatitis
Diffuse dermatitis
Non-granulomatous
Granulomatous
Skin appendages disorders
Panniculitis/ fasciitis
Folliculitis/ perifolliculitis Alopecia
Without vascular damage
Sarcoidal/ epithelioid cell
Inflammatory vascular reaction
Tuberculoid/ caseating
Vasculitis
Foreign body Suppurative
Palisading/ necrobiotic Elastolytic
Alterations of stratum corneum and epidermis Hyperkeratosis with parakeratosis (focal/diffuse)
Hyperorthokeratosis
Hypogranulosis
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Normal granular layer or hypergranulosis
Alterations of basal layer melanin
Hypopigmentation (focal/diffuse)
Hyperpigmentation (focal/diffuse)
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Essen%al Dermatopathology
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Non-inflammatory dermal alterations
Atrophy
Papillary dermis
Reticular dermis
Deposition of material
Hypertrophy fibrosis
Pigmentary alterations
Near Normal Skin Biopsy Epidermis Superficial fungal infection Porokeratosis
Ichthyosis
Hypo-/ Hyperpigmentation
Dermis Deposition
Subtle cellular infiltrates
Connective tissue
Macular amyloidosis
Melanocytosis
Connective tissue nevus
Mucinosis
Urticaria pigmentosa
Atrophoderma
Argyria
Urticaria
Subcutis Absence of normal structures Epithelial
Anhidrotic ectodermal dysplasia
Stromal
Parasites
Lipoatrophy
Onchocerciasis
Anetoderma
Cutiis laxa
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