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Membrane Filtration: Know How To Select Membrane For Lab Testing

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MEMBRANE FILTRATION: KNOW HOW TO CHOOSE MEMBRANES


Key takeaways:

Things to discuss: Membrane-sample Compatibility Polytetrafluoroethylene (PTFE) Membrane Polyvinylidene Fluoride (PVDF) Membrane Nylon (NYL) Membrane Polyethersulfone (PES) Membrane Polypropylene (PP) Membrane Charting compatibility


Membrane-sample Compatibility

Polytetrafluoroethylene (PTFE) Membrane

When selecting a filter or device for sample filtration, it's easy to neglect membrane compatibility.

PTFE is a widely used substance that wide operating temperature range and is resistant to various chemicals. When should we use it? Do use to filter solvents and other harsh substances like acetone and DMSO. Maybe use when we need to filter aqueous solutions and sodium hydroxide. We will need to pre-wet it using watermiscible solvent, like methanol, to succeed in the hydrophobicity of the membrane.

Good membrane-sample compatibility promotes efficient filtration and reduces resistance, resulting in poor compatibility that might cause backpressure, ineffective filtration, or even a chemical attack on your membrane, resulting in contamination in the filtrate.


Polyvinylidene Fluoride (PVDF) Membrane PVDF is a hydrophobic material that can change to become hydrophilic. It is resistant to a wide range of organic solvents.

Nylon (NYL) Membrane Hydrophilic by nature, having broad chemical compatibility and good resistance to organic solvents. Nylon is ideal for high-pH samples, but it should avoid in protein recovery applications.


Polyethersulfone (PES) Membrane

Polypropylene (PP) Membrane

Filters aqueous and certain organic liquids in a range of settings because it is hydrophilic. PES is an excellent choice For high pH applications.

Polypropylene, which comes in membrane and nonwoven forms, is slightly hydrophobic and resistant to a wide variety of chemicals and temperatures.


Charting Compatibility This fast summary should assist you in determining the best membrane-solvent combination for your application. Review the chemical compatibility table in our guide to laboratory membrane filtering principles and chemical compatibility to compare all Membrane Filters and solvents.


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