Sigma - OTC Promotions February 2025

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FEBRUARY

PRICES VALID FROM

BACK PAIN AND HEADACHES ARE THE MOST COMMON PAINS SUFFERED BY PEOPLE 1

Recommending pain relief doesn’t have to be painful for pharmacy staff. Over-the-counter (OTC) treatments can be effective in managing common pain conditions, so you can make a real difference to patients and help reduce the headache of frustrated patients.

Pharmacists and pharmacy team members play a valuable role in offering informed self-care advice to patients, taking into consideration age, existing health problems or personal choice. If your patients are coming to you because they’re struggling to find something that works for them, they’re not alone. In fact, a survey of 1000 UK shoppers showed that 57% with body pains have trouble finding OTC pain relief that work for them.1

These patients should have tried ibuprofen or paracetamol already but not got the relief they want for their mild to moderate pain. That’s where the expert advice of the pharmacy team comes in.

23.5%

want better options to relieve their pain 1

If codeine combinations are your go-to recommendations for these patients, it might be time to reconsider.

Around 60% of pharmacy staff think codeine combination products are the most effective pain relievers from a range of OTC analgesics. 3 † Research shows a paracetamol + ibuprofen combination is actually more effective when it comes to easing patients’ pain for up to 12 hours. 2*

Did you know BASH and NICE guidelines do not recommend the use of opioids including codeine in acute headaces such as headache or migraine? 4,5 ‡

BASH, British Association for the Study of Headache. *Based on a clinical trial. †Online survey of 205 UK pharmacy staff comparing product recommendations for various type of pain, including Nurofen. ‡OTC codeine is only available as a combination product, not as a single active. IT CAN BE HARD FOR PATIENTS TO FIND THE RIGHT PAIN RELIEF 1

TIME TO TRY SOMETHING ELSE?

If a patient has already tried paracetamol or ibuprofen but have not got the relief they needed, you now have a new GSL option available to help them get back to feeling like themself – Nuromol Dual Action Pain Relief.

What makes Nuromol Dual Action Pain Relief different to single active products?

1x Nuromol Dual Action Pain Relief tablet

Simple and convenient dosing : Take 1 tablet, if 1 tablet does not control symptoms a maximum of 2 tablets may be taken, up to 3 times a day 7 Nuromol Dual Action Pain Relief contains interlocking paracetamol and ibuprofen, 6 which are released simultaneously to deliver a combination effect 7 12 hours

Provides statistically superior pain relief than a 1 g paracetamol + 30 mg codeine combination up to 12 hours 2*

6s

THINGS TO REMEMBER 7

• Advise patients Nuromol Dual Action Pain Relief cannot be used alongside other oral or topical NSAIDs or paracetamol

• To minimise side effects, it is recommended that patients take Nuromol Dual Action Pain Relief with food

• If patients still need pain relief after using Nuromol Dual Action Pain Relief for 3 days, they should see their GP for advice

*Based on a clinical trial.

CUSTOMER CONVERSATIONS

A 25-year-old lady

I’ve got a sore back from sleeping funny and I really need to get on with things ”

• She has had back pain for a couple of days but no other symptoms

• She is not taking any other medication

• She has tried standard ibuprofen but it hasn’t helped in relieving her pain

Paracetamol is not recommended for use on its own in NICE’s low back pain guidelines ibuprofen has failed to ease her pain, Nuromol Dual Action Pain Relief could give her the relief she needs to get on with her day.

• He has a painful ankle joint that is tender and swollen

• He can move his ankle and is able to bear his weight

• Doctor advised self-management with PRICE and OTC pain relief 10

• He has been taking paracetamol but the ankle is still swollen and he wants something else to manage the pain

As the patient is not getting the relief he wants with paracetamol alone, a combination ibuprofen + paracetamol formulation like Nuromol Dual Action Pain Relief could help. 7

PRICE, Protect, Rest, Ice, Compression, Elevation. 10

Recommending effective pain relief doesn’t have to be painful

THINK NUROMOL DUAL ACTION PAIN RELIEF

NEW GSL NEW GSL LICENCE LICENCE

6s & 16s also available.

References: 1. Kantar Worldpanel Pain LinkQ Study, data to December 2020 (n=1000). February 2021. placebo-controlled trial comparing the efficacy and tolerability of analgesic combinations including a novel single-tablet combination of ibuprofen/paracetamol for postoperative dental pain. Pain. 2011;152:632–642. 3. Pharmacy staff survey on oral analgesia. CIG research. 2021. (n=205). 12s: diagnosis and management. Clinical guidelines 150. September 2012. Updated December 2021. https://www.nice.org.uk/guidance/cg150. Association for the Study of Headache. National Headache Management System for Adults 2019. https://www.bash.org.uk/downloads/guidelines2019/01_ BASHNationalHeadache_Management_SystemforAdults_2019_guideline_versi.pdf

2007. Data on File. 7. Nuromol Dual Action Pain Relief 200 mg/500 mg Tablets. Summary of Product Characteristics. Updated December 2021. Accessed May 2022. https://www.medicines.org.uk/emc/product/4967. 8. NICE. Clinical Knowledge Summaries. Back pain – low (without radiculopathy). Revised November 2020. Accessed May 2022. https://cks.nice.org.uk/topics/back-pain-low-without-radiculopathy/management/management/. sciatica in over 16s: assessment and management. November 2016. Updated December 2020. Accessed May 2022. https://www.nice.org.uk/guidance/ng59. 10. NICE. Clinical Knowledge Summaries. Sprains and strains. Revised April 2020. Accessed May 2022. https://cks.nice.org.uk/topics/sprains-strains/.

Essential Information: Nuromol Dual Action Pain Relief ibuprofen 200 mg/paracetamol 500 mg. temporary relief of mild to moderate pain which has not been relieved by ibuprofen or paracetamol individually such as migraine, headache, backache, period pain, dental pain, rheumatic and muscular pain, cold and flu symptoms, sore throat and fever. Licence Holder: Reckitt Benckiser Healthcare (UK) Limited, Slough, SL1 3UH. MRRP: £2.49 for 6 tablets, £3.99 for 12 tablets & £4.99 for 16 tablets. Legal Classification: GSL. Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at https://www.medicines.org.uk/emc/product/4967.

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard or search for the MHRA Yellow Card in the Google Play or Apple App Store. Adverse events should also be reported to Reckitt Benckiser Healthcare (UK) ltd on: 0333 200 5345

RB-M-104702 June 2022

Nuromol provides more effective pain relief than a prescription combination of paracetamol and codeine 1*

Nuromol gets to work faster than individual tablets of standard ibuprofen and paracetamol taken together 2–7 †

Powerful

Pain Relief 1,8,10,11

FROM THE MAKERS OF NUROFEN

*Paracetamol 1000 mg + codeine 30 mg . †Based on absorption.

References: 1. Daniels SE, et al Pain. 2011;152:632–642. 2. Tanner T, et al. BMC Clin Pharmacol. 2010;10:10. 3. Wright CE, et al. Clin Pharmacol Ther. 1983;34(5):707-710. 4. Yue Y, et al. Clin Ther. 2013;35(9):1306-1320. 5. Rostami-Hodjegan A, et al. Drug Dev Ind Pharm. 2022;28(5):523-531. 6. Atkinson HC, et al. J Bioequivalence & Bioavailab. 2015;7:3. 7. Tarabar S, et al. Drugs R D. 2020;20:23-37. 8. Nuromol Pain Relief 200 mg/500 mg Film Coated Tablets. Summary of Product Characteristics. Updated June 2022. Accessed January 2023. 9. Survey of Community Pharmacists Aug-Sep 2022. 10. Mehlisch D, et al. Clin Ther. 2010;32(5):882-895. 11. Mehlisch D, et al. Clin Ther. 2010;32(6):1033-1049.

Essential Information

Nuromol Pain Relief 200 mg/500 mg film coated tablets For the temporary relief of mild to moderate pain associated with migraine, headache, backache, period pain, dental pain, rheumatic and muscular pain, pain of non-serious arthritis, cold and flu symptoms, sore throat and fever. This product is especially suitable for pain which has not been relieved by ibuprofen or paracetamol alone. Nuromol Pain Relief 200mg/500mg Film Coated Tablets is indicated in adults aged 18 years. Licence Holder: Reckitt Benckiser Healthcare (UK) Limited, Slough, SL1 3UH. Legal Classification: P. Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at https://www.medicines.org.uk/emc/product/13804.

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard, or search for the MHRA Yellow Card in the Google Play or Apple App Store. Adverse events should also be reported to Reckitt Benckiser Healthcare (UK) ltd on: 0333 200 5345

RKT-M-09246 January 2022

Nasal symptoms from flu and cold?

Sterile natural soothing saline sprays by NeilMed.

Contains only purified water, sodium chloride, and sodium bicarbonate; USP-graded (purity level ≥99%)

• Isotonic

• Non-burning

• Delivers a fine and gentle mist

• Use as often as needed

• Isotonic

• Non-burning

• Use as often as needed

• Hypertonic (2,7%)

• Reduces congestion and swelling better than isotonic spray

• Use as often as needed

neilmed.uk

neilmed.uk

Retail Category Management

Guidance and product information for OTC brands and categories to help support the pharmacy team.

See this month’s book for offers on products featured in the Retail Category Management.

Pain Relief
Gastro Resistant
Ear Treatment
Skincare

BACK PAIN AND HEADACHES ARE THE MOST COMMON PAINS SUFFERED BY PEOPLE 1

Recommending pain relief doesn’t have to be painful for pharmacy staff. Over-the-counter (OTC) treatments can be effective in managing common pain conditions, so you can make a real difference to patients and help reduce the headache of frustrated patients.

Pharmacists and pharmacy team members play a valuable role in offering informed self-care advice to patients, taking into consideration age, existing health problems or personal choice. If your patients are coming to you because they’re struggling to find something that works for them, they’re not alone. In fact, a survey of 1000 UK shoppers showed that 57% with body pains have trouble finding OTC pain relief that work for them.1

These patients should have tried ibuprofen or paracetamol already but not got the relief they want for their mild to moderate pain. That’s where the expert advice of the pharmacy team comes in.

If codeine combinations are your go-to recommendations for these patients, it might be time to reconsider.

Around 60% of pharmacy staff think codeine combination products are the most effective pain relievers from a range of OTC analgesics. 3 † Research shows a paracetamol + ibuprofen combination is actually more effective when it comes to easing patients’ pain for up to 12 hours. 2*

Did you know BASH and NICE guidelines do not recommend the use of opioids including codeine in acute headaces such as headache or migraine? 4,5 ‡

BASH, British Association for the Study of Headache. *Based on a clinical trial. †Online survey of 205 UK pharmacy staff comparing product recommendations for various type of pain, including Nurofen. ‡OTC codeine is only available as a combination product, not as a single active.

TIME TO TRY SOMETHING ELSE?

If a patient has already tried paracetamol or ibuprofen but have not got the relief they needed, you now have a new GSL option available to help them get back to feeling like themself – Nuromol Dual Action Pain Relief.

What makes Nuromol Dual Action Pain Relief different to single active products?

Nuromol Dual Action Pain Relief contains interlocking paracetamol and ibuprofen, 6 which are released simultaneously to deliver a combination effect 7

Simple and convenient dosing : Take 1 tablet, if 1 tablet does not control symptoms a maximum of 2 tablets may be taken, up to 3 times a day 7

1x Nuromol Dual Action Pain Relief tablet

Provides statistically superior pain relief than a 1 g paracetamol + 30 mg codeine combination up to 12 hours 2*

THINGS TO REMEMBER 7

• Advise patients Nuromol Dual Action Pain Relief cannot be used alongside other oral or topical NSAIDs or paracetamol

• To minimise side effects, it is recommended that patients take Nuromol Dual Action Pain Relief with food

• If patients still need pain relief after using Nuromol Dual Action Pain Relief for 3 days, they should see their GP for advice

*Based on a clinical trial.

CUSTOMER CONVERSATIONS

A 25-year-old lady

I’ve got a sore back from sleeping funny and I really need to get on with things ”

• She has had back pain for a couple of days but no other symptoms

• She is not taking any other medication

• She has tried standard ibuprofen but it hasn’t helped in relieving her pain

Paracetamol is not recommended for use on its own in NICE’s low back pain guidelines ibuprofen has failed to ease her pain, Nuromol Dual Action Pain Relief could give her the relief she needs to get on with her day.

• He has a painful ankle joint that is tender and swollen

• He can move his ankle and is able to bear his weight

• Doctor advised self-management with PRICE and OTC pain relief 10

• He has been taking paracetamol but the ankle is still swollen and he wants something else to manage the pain

As the patient is not getting the relief he wants with paracetamol alone, a combination ibuprofen + paracetamol formulation like Nuromol Dual Action Pain Relief could help. 7

PRICE, Protect, Rest, Ice, Compression, Elevation. 10

Recommending effective pain relief doesn’t have to be painful

THINK NUROMOL DUAL ACTION PAIN RELIEF

NEW GSL NEW GSL LICENCE LICENCE

6s & 16s also available.

References: 1. Kantar Worldpanel Pain LinkQ Study, data to December 2020 (n=1000). February 2021. placebo-controlled trial comparing the efficacy and tolerability of analgesic combinations including a novel single-tablet combination of ibuprofen/paracetamol for postoperative dental pain. Pain. 2011;152:632–642. 3. Pharmacy staff survey on oral analgesia. CIG research. 2021. (n=205). 12s: diagnosis and management. Clinical guidelines 150. September 2012. Updated December 2021. https://www.nice.org.uk/guidance/cg150. Association for the Study of Headache. National Headache Management System for Adults 2019. https://www.bash.org.uk/downloads/guidelines2019/01_ BASHNationalHeadache_Management_SystemforAdults_2019_guideline_versi.pdf

2007. Data on File. 7. Nuromol Dual Action Pain Relief 200 mg/500 mg Tablets. Summary of Product Characteristics. Updated December 2021. Accessed May 2022. https://www.medicines.org.uk/emc/product/4967. 8. NICE. Clinical Knowledge Summaries. Back pain – low (without radiculopathy). Revised November 2020. Accessed May 2022. https://cks.nice.org.uk/topics/back-pain-low-without-radiculopathy/management/management/. sciatica in over 16s: assessment and management. November 2016. Updated December 2020. Accessed May 2022. https://www.nice.org.uk/guidance/ng59. 10. NICE. Clinical Knowledge Summaries. Sprains and strains. Revised April 2020. Accessed May 2022. https://cks.nice.org.uk/topics/sprains-strains/.

Essential Information: Nuromol Dual Action Pain Relief ibuprofen 200 mg/paracetamol 500 mg. temporary relief of mild to moderate pain which has not been relieved by ibuprofen or paracetamol individually such as migraine, headache, backache, period pain, dental pain, rheumatic and muscular pain, cold and flu symptoms, sore throat and fever. Licence Holder: Reckitt Benckiser Healthcare (UK) Limited, Slough, SL1 3UH. MRRP: £2.49 for 6 tablets, £3.99 for 12 tablets & £4.99 for 16 tablets. Legal Classification: GSL. Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at https://www.medicines.org.uk/emc/product/4967.

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard or search for the MHRA Yellow Card in the Google Play or Apple App Store. Adverse events should also be reported to Reckitt Benckiser Healthcare (UK) ltd on: 0333 200 5345

RB-M-104702 June 2022

AN INCREASING NUMBER OF PATIENTS WITH HEARTBURN NEED YOUR ADVICE 1

The main drivers for increased prevalence could include:1,2

Certain food and drink can trigger heartburn or make it worse including coffee, alcohol, chocolate and fatty or spicy foods. 2

SEASONAL EVENTS AGE OBESITY

In 2022, 19% of people in the UK were aged 65 or over. This is projected to increase to 27% by 2072.3

In 2022 to 2023, 64% of adults in England were estimated to be overweight or living with obesity. 4

The food eaten during occasions such as Christmas, Easter, Eid, or summer barbecues may trigger increased rates of heartburn.

A GROWING CATEGORY FOR PHARMACISTS

The indigestion market in the UK is worth £217 million annually, and has grown by 6.9% vs last year.⁵

Within this market, the Proton Pump Inhibitor (PPI) segment is worth £50 million, with Nexium Control holding the largest value share, and 11% of the total indigestion market by value.⁵

FREQUENT HEARTBURN (MORE THAN ONCE A WEEK) CAN SIGNIFICANTLY IMPACT A PATIENT’S QUALITY OF LIFE. 6-8

It is estimated that 25% of adults in the UK suffer from heartburn. 9 The prevalence of heartburn is increasing worldwide, linked to ageing populations and increased rates of obesity.10

3 out of 4 sufferers report that heartburn interferes with their sleep.6

DO MORE THAN JUST TREAT THE BURNING PAIN OF HEARTBURN; TACKLE IT AT ITS SOURCE

Acid reflux, a cause of heartburn, occurs when stomach acid moves up into the oesophagus, causing irritation.11

Heartburn treatments like antacids and alginates address the symptoms of heartburn, but not the cause.12,13 Nexium Control acts to reduce production of stomach acid, helping to block heartburn at the source.14 NICE guidelines recommend PPIs as a first line treatment for frequent heartburn,15 and unlike alginates and antacids which only provide short-acting relief, Nexium Control provides up to 24 hours of heartburn protection.14

Duration of relief Affects acid production

Mode of action

Dosing

Once in contact with acid produces salt & water –neutralising contents

As required throughout the day for short acting relief

Form a surface or ‘raft’ over stomach contents to stop reflux

As required after meals and at bedtime for short acting relief

Blocks the proton pump in parietal cells to reduce acid production

One a day for 24 hour

NEXIUM CONTROL OFFERS PATIENTS UP TO 24 HOUR HEARTBURN PROTECTION FROM LESS THAN 80P A DAY 16

GIVE YOUR PATIENTS LONGER-LASTING ACID CONTROL* 18

The active ingredient in Nexium Control is esomeprazole, a PPI. Esomeprazole is the first PPI developed as a single optical isomer.19

Compared to omeprazole 20mg, another PPI, Nexium Control 20mg provides: 18

70% higher plasma concentration

More consistent effects between individuals

Longer lasting acid control

THE POWER OF NEXIUM CONTROL FOR HEARTBURN RELIEF

8 OUT OF 10 4 OUT OF 5 NIGHTS 2 WEEKS 20mg

Almost 8 out of 10 people reported first resolution of their heartburn with the first week of treatment.

4 out of 5 nights were heartburn-free.

Esomeprazole raised scores of nearly every quality-oflife parameter impacted by heartburn to normal levels within 2 weeks of use.7

ESOMEPRAZOLE
*Vs omeprazole

THE NEXIUM CONTROL RANGE

Start here for those using PPIs for the first time 1 week supply

ADVICE FOR PATIENTS WITH FREQUENT HEARTBURN

DO DON'T

Eat smaller, more frequent meals

Raise one end of your bed 10-20cm –your chest and head should be above the level of your waist, so acid does not travel up into your throat

Try to lose weight if you are overweight

Try to find ways to relax

Consider giving up smoking

Have food or drink which triggers symptoms

Do not eat within 3 to 4 hours of bed

Do not wear tight clothes around your waist

Do not smoke or drink too much alcohol

Do not stop taking any prescribed medicines before speaking to a doctor first

References: 1. Yamasaki T, et al. JNM Journal. 2018; 24(4). 2. Heartburn and acid reflux. NHS. Available at https://www.nhs.uk/conditions/heartburn-and-acid-reflux/. Accessed September 2024. 3. House of Commons Library. The UK’s changing population. July 2024. Available at: https://commonslibrary.parliament.uk/the-ukschanging-population. Accessed September 2024. 4. Gov.uk. Obesity Profile: short statistical commentary May 2024. Available at: https://www.gov.uk/government/ statistics/update-to-the-obesity-profile-on-fingertips/obesity-profile-short-statistical-commentary-may-2024 . Accessed September 2024. 5. IRI all outlets including chemists 52 w/e 31/8/24 6. Farup C et al. Arch Intern Med. 2001;161:45-52. 7. Kulig M et al. Aliment Pharmacol Ther. 2003;18:767-76. 8. Ware JE Jr, Sherbourne CD. Med Care. 1992;30:473-83. 9. Heartburn and Acid Reflux. Guts UK! https://gutscharity.org.uk/advice-and-information/symptoms/heartburn-and-reflux/. 10. Sweis R, Fox M. The global burden of gastro-oesophageal reflux disease: more than just heartburn and regurgitation. Lancet Gastroenterol Hepatol. 2020 Jun;5(6):519-521. 11. Hsu M, Safadi AO, Lui F. Physiology, Stomach. 2023 Jul 17. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan. b13 12. Salisbury BH, Terrell JM. Antacids. [Updated 2022 Aug 15]. 13. Leiman DA, Riff BP, Morgan S, Metz DC, Falk GW, French B, Umscheid CA, Lewis JD. Alginate therapy is effective treatment for GERD symptoms: a systematic review and meta-analysis. Dis Esophagus. 2017 May 1;30(5):1-9. 14. National Center for Biotechnology Information (2023). PubChem Compound Summary for CID 9568614, Esomeprazole. Retrieved September 1, 2023 from https://pubchem.ncbi.nlm.nih.gov/compound/Esomeprazole. 15. NICE guidelines, CG184 Sept 2014. 16. Chemist & Druggist price list. May 2024. 17. IRI All Outlets GB inc Chemists, unit sales, L12 w/e 17.08.2024. 18. Lind et al. Alimentary Pharmacology and Therapeutics, 2000; 14:861-867. 19. Tonini M et al. (2001) Clinical pharmacology and safety profile of esomeprazole, the first enantiomerically pure proton pump inhibitor; Digest liver Dis 2001;33:600-6.

Product information: Nexium Control 20 mg gastro-resistant tablets and Nexium Control 20mg gastro-resistant hard capsules. Active ingredient: Esomeprazole Indications: The short-term treatment of reflux symptoms (e.g. heartburn and acid regurgitation) in adults. Legal category: GSL: 14s capsules, 7s tablets, and 14s tablets P: 28s tablets. PL holder: Haleon UK Trading Limited, The Heights, Weybridge, Surrey, KT13 0NY, U.K.

Information about these products, including adverse reactions, precautions, contraindications, and method of use can be found at: https://www.medicines.org.uk/emc/product/819/smpc, https://www.medicines.org.uk/emc/product/14465/smpc, https://www.medicines.org.uk/emc/product/3660/smpc

Trademarks are owned by or licensed to the Haleon group of companies. PM-GB-NEX-24-00037

N betaine
Glycerin

Nuromol provides more effective pain relief than a prescription combination of paracetamol and codeine 1*

Nuromol gets to work faster than individual tablets of standard ibuprofen and paracetamol taken together 2–7 †

Powerful

Pain Relief 1,8,10,11

FROM THE MAKERS OF NUROFEN

*Paracetamol 1000 mg + codeine 30 mg . †Based on absorption.

References: 1. Daniels SE, et al Pain. 2011;152:632–642. 2. Tanner T, et al. BMC Clin Pharmacol. 2010;10:10. 3. Wright CE, et al. Clin Pharmacol Ther. 1983;34(5):707-710. 4. Yue Y, et al. Clin Ther. 2013;35(9):1306-1320. 5. Rostami-Hodjegan A, et al. Drug Dev Ind Pharm. 2022;28(5):523-531. 6. Atkinson HC, et al. J Bioequivalence & Bioavailab. 2015;7:3. 7. Tarabar S, et al. Drugs R D. 2020;20:23-37. 8. Nuromol Pain Relief 200 mg/500 mg Film Coated Tablets. Summary of Product Characteristics. Updated June 2022. Accessed January 2023. 9. Survey of Community Pharmacists Aug-Sep 2022. 10. Mehlisch D, et al. Clin Ther. 2010;32(5):882-895. 11. Mehlisch D, et al. Clin Ther. 2010;32(6):1033-1049.

Essential Information

Nuromol Pain Relief 200 mg/500 mg film coated tablets For the temporary relief of mild to moderate pain associated with migraine, headache, backache, period pain, dental pain, rheumatic and muscular pain, pain of non-serious arthritis, cold and flu symptoms, sore throat and fever. This product is especially suitable for pain which has not been relieved by ibuprofen or paracetamol alone. Nuromol Pain Relief 200mg/500mg Film Coated Tablets is indicated in adults aged 18 years. Licence Holder: Reckitt Benckiser Healthcare (UK) Limited, Slough, SL1 3UH. Legal Classification: P. Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at https://www.medicines.org.uk/emc/product/13804.

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard, or search for the MHRA Yellow Card in the Google Play or Apple App Store. Adverse events should also be reported to Reckitt Benckiser Healthcare (UK) ltd on: 0333 200 5345

RKT-M-09246 January 2022

Summary of Terms

1. Where accounts have been approved for credit, payments are due 30 days from the month of invoice. Sigma Pharmaceuticals Plc reserves the right to charge interest on overdue accounts at the rate of 4% above the LIBOR (London InterBank Offered Rate) per month without prejudice to the right of recovery. Cheques payable to Sigma Pharmaceuticals Plc. Sigma Pharmaceuticals Plc reserves the right not to process the orders in case of an overdue account.

2. All orders and prices quoted are subject to the standard rate or reduced rate of V.A.T. on the NETT invoice value. The invoice date is the tax point for V.A.T. purposes.

3. Products on offer in the PLOF are not eligible for any further discounts.

4. All delivery enquiries must be notified within 24 hours of delivery

5. Prices are correct at time of going to print, but are subject to change without prior notice. Sigma Pharmaceuticals Plc reserves the right to amend any of their prices without due notice. Orders are accepted on condition that the goods will be invoiced at the prices ruling at the date of delivery. All images shown are for illustrative purposes only.

6. Invoice queries must be raised within one week of invoice date.

7. The goods shall remain the sole and absolute property of the seller and legal equitable owner until such time as the buyer shall have paid to the seller the agreed price together with the full price of any other contract with the seller.

8. Standard terms and conditions apply, as per trading terms, available upon request.

9. RSP’s shown are supplied by the manufacturers and are correct at time of going to print. It is at the retailers discretion to set their own retail price and margin.

Claims and Returns

DELIVERIES

When accepting your delivery please ensure the number of boxes/bulk received match the drivers runsheet and that any discrepancies are clearly marked. Non-delivery must be notified to Sigma Pharmaceuticals Plc within 1 service day of invoice date or advice of despatch.

RETURNS

Under existing rules and regulations issued by the DHSS and as published in “MAIL”, goods will only be accepted for return by Sigma Pharmaceuticals Plc for the following reasons:

• To correct an error in delivery or ordering.

• In response to a product or batch recall instigated by a manufacturer.

• Where products or packages are alleged to be faulty.

In order to be considered for credit or replacement the goods must be accompanied by a note showing:-

• The name and address of the customer returning the goods.

• The quantity and description of the goods.

• The invoice number on which the goods were supplied.

• The reason of the return.

Transfer Order Queries

Call 01923 331 411 and ask for the Transfer Order Department.

Expiry Date Queries

Dates on products should be checked upon delivery. If you wish to return an item due to the date, please follow the return procedure mentioned previously.

Items Missing From Delivery

Call 01923 444 999 within 24 hours of delivery.

Wrong Item Supplied

Mark the required item with the code of ‘B’ on your invoice/return slip.

Goods Ordered in Error

Mark the item with the code of ‘H’ on your invoice/return slip.

Goods Arrived Damaged

Mark the item with the code of ‘F’ on your invoice/return slip.

Recall Stock

All recall stock must be written on a return slip with the date, quantity and reason code K.

OTC & HEALTH AND BEAUTY TRANSFER ORDER OVERVIEW

Sigma offers a comprehensive transfer order service offering prompt deliveries, transparent invoicing and full advantage of manufacturers multi-level discounts (MLD) across a wide range of manufacturers.

WHY USE SICMA FOR TRANSFER ORDERS?

Our transparent invoice structure, quick turnaround and dedicated customer service means we are the preferred choice with manufacturers and third-party sales teams for transfer orders. Advantages of putting your transfer orders through Sigma:

> A minimum of 10% wholesaler discount on transfer orders)(-.

> Transparent discount structure

> More than 95% of products are available to order in singles

> Aim to deliver stock within 48 hours from receipt

> Back orders held for 60 days

> Dedicated transfer order team that can be directly contacted by telephone or email.

> Committed to ensure transfer order queries are resolved within 72 hours "Ethical and Rx Lines may not qualify for this discount

TRANSFER ORDER PORTFOLIO

BAYER

BIOKULT

•Alka Seltzer

• Protexin

• Bepanthen

• Berocca

• Mum

CLAXO SMITH l{LINE

CIGA HEALTHCARE

• Odoreaters

·ORS

HALEON

• Otex

LASER HEALTHCARE

· Alli

Allevia

•Aquafresh

Buscopan

• Beechams

BR PHARMACEUTICALS

• Canesfresh

• Canesten

• Valupak

• Clarityn

• Diprobase

CEUTA HEALTHCARE

•Feminax

• 4 Head

•Germolene

• Aloclair

• Germoloids

• Anbesol

• Redoxon

• Rennie

• Ashton & Parsons

• Astral

• Sanatogen

• Belladonna

• Blistex

BE T TERYOU

• Bloateze

BIOl{ULT

• Bodyform

• Breathe Right

• Protexin

• Carnation

• Chewy Vites

BR PHARMACEU TICALS

• Chloralieve

• GoldenEye

• Valupak

• Hydromol

• Ibuleve

CARE FOR YOURSELF LTD

• Lypsyl

•AMO

• Macushield

• Milton

CEU TA HEALTHCARE

• MolluDab

• 4head

• Murine

•Alliance Pharma

• Odor - Eaters

• ORS

• Bayer

• Bazuka

• Otex

•Chloralieve

• Pepto Bismol

• Blistex

• Seven Seas

• Tena

• Bodyform

• ThermaCare

• Carnation

• Ultra Chloraseptic

• Uvistat

• Flexiseq

• Freederm

• Vamousse

•lbuleve

• Viagra Connect

Aquafresh

•Pepto Bismol

• Fastaid

Beechams

Biotene

• Tena

Breathe Right

•Ultra Chloraseptic

• Vapodrops

Corsodyl

Nurses

• Viagra Connect

• Vicks

Driclor

Enos

• Westlab

Eumovate

Lamisil

CHURCH AND DWICHT

Nicotinell

•Anusol

Otrivine

•Arm & Hammer

Panadol

• Batiste

Piriton

• Femfresh

Poligrip

Sensodyne

•First Response

• Nair

Voltarol

Zovirax

• Orajel

• Pearl Drops

• Replens

• Sterimar

CICA HEALTHCARE

ETHICOE

• Balance Activ

•Glucogel

·Lift

•Nelsons

•Diffiam

·CBl2

•Clearblue CR LANE

•Aquaban

• Derbac

• Earex

• l<alms

• Vicks

· lglu

• Milton

• Vicks Vapodrops

• Murine

• Wisdom

•Jakemans

· Olbas

•Pro Plus

• Teangi Tea Tree

Cialis Together

• Biotene

• Breathe Right

Dulco Range

• Corsodyl

Maalox

•Day Nurse

Nasacort

Opticrom

• Driclor

Pharmaton

• Duofilm

• Enos

Phenergan

Clearblue

• Eumovate

Fixodent

• Lamisil

• Nicotinell

Deep Freeze / Heat / Relief

• Otrivine

Mentholatum Ibuprofen

Mentholatum Vapour Rub

• Panadol

• Piriton

Elastoplast

Eucerin

• Poligrip

Nivea

• Polytar

Ulipristal

• Scopoderm

Just For Men

• Sensodyne

• Voltarol

Vagisil

Anthisan

• Zovirax

Cepton

Dalvit

l{ARIUM LTD

Dentinox

Dioralyte

•Cuticura

• Perspirex

Snufflebabe

Syndol

LASER HEALTHCARE

Difflam

Ricola

•Anthisan

Dextro

• Brolene

Fisherman’s Friend

• Buscopan

Bazuka

• Beiersdorf

Doublebase

• Bazuka

Freederm

•Compeed

• Dextro

Iglu

•Deep Heat/ Deep Freeze

• Dioralyte

• Dulcolax

• EllaOne

•Just For Men

•Fishermans Friend

· Nitty Gritty

PERRIGO (Omega Pharma)

Abidec

Alphosyl

Beconase

Bio-Oil

Bronchostop

Contac

Dentu Crème

Lactacyd

Lyclear

Milk Of Magnesia

NiQuitin

Nytol

Solpadeine

Tiger Balm

Veganin

Wartner

Wernets

POWERMED PLUS

Anusol

Arm & Hammer

Batiste

Femfresh

First Response

Karium

Lotil

Nair

Orajel

Pearl Drops

Replens

Salonpas

Sterimar

RECKITT BENCKISER

Bonjela

Cuprofen

Dettol

Disprin

Durex

Full Marks

Fybogel

Gaviscon

Guardium

Lanacane

Lemsip

Nurofen

Optrex

Paramol

Senokot

Steradent

Strepsil

Sweetex

Veet

Woodwards

THE MILES GROUP

A L Simpkin

Cambridge Healthcare

Colgate Palmolive

Comedic International

Alpecin

Plantur

Kobayashi

MS George

Omron

Passion For Life

Profoot

Quies

THEA PHARMACEUTICALS

Blephaclean

Hyabak

Thealoz

Otrivine

Nutrof

Monopost

THORNTON & ROSS

Acriflex

Alegesal

Care

Cetraben

Covonia

Eucryl

Eurax

Flexitol

Fultium

Hedrin

Metanium

Movelat

Mycota

Oilatum

Radian B

Savlon

Senna

Virasorb

Virasoothe

Windsetlers

Zeroderm

Tel: 0800 597 4462, Option 3

Email: cs@sigmaplc.com

Email: rushin@sigmaplc.com

Tel: 0800 597 4462, Option 3

Email: hitesh@sigmaplc.com

Sharon Walker, Customer Services Manager

Tel: 0800 358 4427

Michelle Sparrow, Business Development Manager

Email: cs@sigmaplc.com

Tel: 01923 332 790

Dipesh Vaja, Head of Sales

Email: michelle@sigmaplc.com

Tel: 0800 597 4462

Head of Sales

Email: dipesh@sigmaplc.com

Business Development

Dipesh Vaja, Head of Sales

Sales Executives

Dipesh Vaja, Head of Sales

Tel: 0800 597 4462

Tel: 0800 597 4462

Michelle Sparrow, Business Development Manager

Tel: 01923 332 790

Telesales/Customer Service

Email: dipesh@sigmaplc.com

Email: dipesh@sigmaplc.com

Email: michelle@sigmaplc.com

Pankaj Vyas - National Sales Manager

Tel: 07946 352 462

Rushin Mehta, Telesales Manager

Email: pankaj@sigmaplc.com

Telesales/Customer Service

Tel: 0800 597 4462, Option 3

Vithal Adatia - Account Executive

Telesales/Customer Service

Sales Executives

Email: rushin@sigmaplc.com

Rushin Mehta, Telesales Manager

Rushin Mehta, Telesales Manager

Tel: 01923 331 407

Hitesh Haria, Telesales Supervisor

Email: vithal@sigmaplc.com

Tel: 0800 597 4462, Option 3

Email: hitesh@sigmaplc.com

Tel: 0800 597 4462, Option 3

Pankaj Vyas - National Sales Manager

Tel: 07946 352 462

Tel: 0800 597 4462, Option 3

Email: rushin@sigmaplc.com

Sharon Walker, Customer Services Manager

Tel: 0800 358 4427

Hinal Pandya, Specials Manager

Email: rushin@sigmaplc.com

Email: pankaj@sigmaplc.com

Tel: 0800 597 4475

Email: cs@sigmaplc.com

Email: specials@sigmaplc.com

Sharon Walker, Customer Services Manager

Hitesh Haria, Telesales Supervisor

Hitesh Haria, Telesales Supervisor

Tel: 0800 597 4462, Option 3

Vithal Adatia - Account Executive

Tel: 0800 597 4462, Option 3

Email: hitesh@sigmaplc.com

Tel: 01923 331 407

Email: hitesh@sigmaplc.com

Email: vithal@sigmaplc.com

Tel: 0800 358 4427

Sharon Walker, Customer Services Manager

Tel: 0800 358 4427

Email: cs@sigmaplc.com

Business Development Team

OTC Transfer Orders

Email: cs@sigmaplc.com

Hinal Pandya, Specials Manager

Tel: 0800 597 4475

Michelle Sparrow, Business Development Manager

Tel: 01923 332 790

Business Development Team

Simone Elkerton OTC Transfer Orders

Email: specials@sigmaplc.com

Tel: 01923 331 411

Business Development

Email: michelle@sigmaplc.com

Email: sim@sigmaplc.com

Michelle Sparrow, Business Development Manager

Lisa Farrant OTC Transfer Orders

Tel: 01923 331 411

Email: lisa@sigmaplc.com

OTC Transfer Orders

Michelle Sparrow, Business Development Manager

Tel: 01923 332 790

Sales Executives

Tel: 01923 332 790

Email: michelle@sigmaplc.com

Email: michelle@sigmaplc.com

Simone Elkerton OTC Transfer Orders

Tel: 01923 331 411

Pankaj Vyas - North London up to Midlands

Tel: 07946 352 462

Business Development

Sales Executives

Email: sim@sigmaplc.com

Sales Executives

Email: pankaj@sigmaplc.com

Lisa Farrant OTC Transfer Orders

Reshma Patel - North East & South London

Tel: 01923 331 411

Tel: 07767 163 171

Email: lisa@sigmaplc.com

Email: reshma@sigmaplc.com

Tel: 01923 444 999

Pankaj Vyas - North London up to Midlands

Email: bd@sigmaplc.com

Specials

Tel: 07946 352 462

Pankaj Vyas - National Sales Manager

Tel: 07946 352 462

Email: pankaj@sigmaplc.com

Email: pankaj@sigmaplc.com

Hinal Pandya, Specials Manager

Tel: 0800 597 4475

Email: specials@sigmaplc.com

Hinal Pandya, Specials Manager

Reshma Patel - North East & South London

Tel: 07767 163 171

Vithal Adatia - Account Executive

Email: reshma@sigmaplc.com

Tel: 01923 331 407

Email: vithal@sigmaplc.com

Hinal Pandya, Specials Manager

Tel: 0800 597 4475

OTC Transfer Orders

Tel: 0800 597 4475

Email: specials@sigmaplc.com

Email: specials@sigmaplc.com

Simone Elkerton OTC Transfer Orders

Tel: 01923 331 411

OTC Transfer Orders

Email: sim@sigmaplc.com

Simone Elkerton OTC Transfer Orders

Lisa Farrant OTC Transfer Orders

Tel: 01923 331 411

Email: lisa@sigmaplc.com

Lisa Farrant OTC Transfer Orders

Simone Elkerton OTC Transfer Orders

Tel: 01923 331 411

Tel: 01923 331 411

Email: sim@sigmaplc.com

Email: sim@sigmaplc.com

Lisa Farrant OTC Transfer Orders

Tel: 01923 331 411

Email: lisa@sigmaplc.com

Tel: 01923 331 411

Email: lisa@sigmaplc.com

*Bodyform voted No.1 for comfort by 69%, and No.1 for protection by 66%, of those surveyed compared with other brands they had previously tried. In-home trial with 325 women aged 18-55, Nov23. Verify at www.bodyform.co.uk/verify. †Cour-V™ Adaptive Technology: Winner Period Care Category. Survey of 8,000 people in UK &

ROI by Kantar.

Brulidine Cream

and Antibacterial

Dual action antiseptic AND antibacterial cream for all the family.

Effective and versatile first aid - active ingredient

Dibrompropamidine Isetionate 0.15%w/w

Recommended for a wide range of indications:

• Minor burns and scalds. Open wounds such as bed sores.

• Cuts and grazes, nappy rash and other minor skin infections.

• Ringworm of the scalp, Inflammation of the skin and Otitis Externa.

• Active against pathogenic Streptococcus and Staphylococcus i including penicillin resistant strains.

• Active in the presence of p u s and blood.

Healthy Mum, Healthy Baby

The Centrum range: expertly designed multivitamins

Centrum Advance A daily Multivitamin supplement that helps meet the nutritional needs of adults.*

Centrum Kids Great tasting chewable multivitamin gummies suitable for children age 4+.*

*2024 UK survey included 203 pharmacists 1. Data on file: UK Pharmacy market research. 203 Pharmacists. April 2024. 2. Difflam 0.15% w/v Spray. SmPC. 2021. Available at: https://www.medicines.org.uk/emc/product/827/smpc/print 3. Difflam 0.15% w/v Spray. PIL. 2021. Available at: https://www.medicines.org.uk/emc/files/pil.827.pdf

Difflam 3 mg Lozenges (benzydamine hydrochloride) Lemon and Orange-Honey. Indications: Difflam™ lozenges is used in adults and children above 6 years of age for symptomatic local treatment for the relief of pain and irritation of the mouth and throat. Legal category: P. Information about this product, including adverse reactions, precautions, contraindications and method of use can be found at: https://www.medicines.org.uk/emc/search?q=difflam+lozenges

Difflam™ Spray (benzydamine hydrochloride 0.15%w/v). Indications: Difflam™ Spray is a locally acting analgesic and anti-inflammatory treatment for the throat and mouth. It is especially useful for the relief of pain in traumatic conditions such as following surgical removal of tonsils, the use of naso-gastric tube or dental surgery. Legal category: P. Information about this product, including adverse reactions, precautions, contraindications and method of use can be found at: https://www.medicines.org.uk/emc/product/827/smpc

Difflam™ Sore Throat Rinse (benzydamine hydrochloride 0.15% w/v) & Difflam™ Oral Rinse (benzydamine hydrochloride 0.15% w/v). Indications: Locally acting analgesic and anti-inflammatory treatment for the relief of painful inflammatory conditions of the throat including pharyngitis. Legal category: P. Information

and

of use can be found at: https://www.medicines.org.uk/emc/product/9258/smpc & https://www.medicines.org.uk/emc/product/9257/smpc Marketing Authorisation Holder: Mylan Products Ltd., Station Close, Potters Bar, Hertfordshire, EN6

heavy menstrual bleeding by up to 60%1 Effective relief from period pain for up to 12 hours2

Scan the QR code to access the pharmacy training hub or visit evanaperiods.com/hcp to learn more

PHARMACY (P) BRANDS

Evana® Heavy Period Relief 500 mg tablets (Tranexamic acid). Reduction of heavy menstrual bleeding over several cycles in women with regular, 21-35-day cycles with no more than 3 days variation. Ultravana® Period Pain Relief 250 mg Gastro-resistant tablets (Naproxen). For the treatment of primary dysmenorrhoea in women aged 15-50 years. Maxwellia Ltd., Alderley Park, Alderley Edge, Cheshire, SK10 4TG. Supply classification: P. Information about these products, including adverse reactions, precautions, contraindications, and method of use can be found at: evanaperiods.com/hcp/. 1. Leminen, H, & Hurskainen, R. Tranexamic acid for the treatment of heavy menstrual bleeding: efficacy and safety. Int J Women’s Health. 2012; 4:413–421., 2. Data on file.

Antiseptic Cream

Effective treatment for minor cuts and grazes, minor burns, scalds and blisters, stings and insect bites, spots and chapped or rough skin

Dual Action formula that:

• Contains local anaesthetic to help with pain relief

• Offers antiseptic action to help prevent infection

Germolene® Antiseptic Cream (Phenol and Chlorhexidine Digluconate). Indications: Antiseptic, local anaesthetic and emollient for minor cuts and grazes, minor burns, scalds, blisters, stings and insect bites, spots and other minor skin conditions, chapped or rough skin. MA Holder: Bayer plc, 400 South Oak Way, Reading, RG2 6AD (information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at: https://mhraproducts4853.blob.core.windows.net/docs/34a67a8c3ed61a7d72acd9114dcc731aabdb09cf). Legal Category: GSL.

Date of Preparation: February 2023.

® = Registered trademark of Bayer AG.

Phenol, Chlorhexidine Digluconate

Floradix Kindervital Fruity

Liquid Calcium and Vitamin Formula

Floradix Kindervital Fruity is a liquid calcium and vitamin formula for children, containing a delicious blend of herbs and fruit juices. Floradix Kindervital Fruity has all the benefits of the original Floradix Kindervital for Children, however it has a fruity taste, is formulated to be 100% gluten free and is suitable for vegans. Floradix Kindervital Fruity safeguards the intake of calcium, vitamins A, D, E, C, B1, niacin, B6 and B12 and is suitable for children from 3 years of age.

Recommended Daily Dose

Children 3 - 6 years: 10ml once daily

Children from 7 years and adults: 10ml twice daily

Floradix Kids

Liquid Iron and Vitamin Formula

Floradix KIDS is based on our well-established Floradix Liquid Iron, however the taste and formula have been produced with children in mind. The main active ingredient is iron which contributes to the normal development of cognitive functions. Floradix KIDS also contains vitamins C, B1, B2, B6, B12 and niacin. The contained acerola and raspberry fruit juice concentrates give the formula a delicious taste. Floradix KIDS is suitable for children from 3 years of age.

Recommended Daily Dose

Children 3 - 6 years: 10ml once daily

Children 7 - 9 years: 15ml once daily

Boys 10 - 13 years: 17.5ml once daily

Girls 10 - 13 years: 20ml once daily

Children from 14 years and adults: 20ml once daily

Floradix Immune Support

Floradix Immune Support is based on an aqueous herbal extract from selected plants and Echinacea. The active ingredients are all selected for their role in the support of the normal function of the immune system; vitamin D3, C, B12, B6, selenium and zinc. Floradix Immune Support contains a mixture of fruit juice concentrates, including elderberry and pomegranate, which give the product a great taste as well as being packed with anti-oxidants.

Recommended Daily Dose

Children 3 - 6 years: 10ml once daily

Children from 7 years and adults: 10ml twice daily

Floradix Vitamin-B-Complex

Liquid Formula

Floradix Vitamin-B-Complex contains vitamins of the B-complex which are involved in a multitude of important metabolic processes in the body.

Vitamins B1, B2, B6, B12 and niacin contribute to normal energy release and to the normal function of the nervous system. Vitamins B2, B6, B12 and niacin contribute to the reduction of tiredness and fatigue. In addition vitamin B1 contributes to the normal function of the heart.

Vitamins B6 and B12 contribute to normal red blood cell formation and to the normal function of the immune system. Biotin, niacin and vitamin B12 contribute to normal skin and psychological functions.

Recommended Daily Dose

Adults and children from 12 years: 20ml once daily

Children 7 - 11 years: 10ml once daily

Children 3 - 6 years: 5ml once daily

Relief from Cold, Allergies, Hay Fever, Nasal & Sinus Symptoms

Over The Counter Products

(No Prescription Required)

SAFE • SIMPLE • EFFECTIVE • AFFORDABLE

Helps Alleviate:

•Nasal Symptoms from Allergies & Hay Fever

•Nasal Symptoms from Cold & Flu

•Post Nasal Drip

•Sinus Pressure & Nasal Stuffiness

•Allergies from Occupational and House Dust, Fumes, Animal Dander, Grass, Pollen, Smoke, etc.

•Nasal Symptoms in CPAP Users with Sleep Apnoea

•To Loosen Thick Nasal Mucous Symptoms seen in Cystic Fibrosis and Immotile Ciliary Syndrome

*If returned within 120 days from date of purchase.

Nuromol provides more effective pain relief than a prescription combination of paracetamol and codeine 1*

Nuromol gets to work faster than individual tablets of standard ibuprofen and paracetamol taken together 2–7 †

*Paracetamol 1000 mg + codeine 30 mg . †Based on absorption.

References: 1. Daniels SE, et al Pain. 2011;152:632–642. 2. Tanner T, et al. BMC Clin Pharmacol. 2010;10:10. 3. Wright CE, et al. Clin Pharmacol Ther. 1983;34(5):707-710. 4. Yue Y, et al. Clin Ther. 2013;35(9):1306-1320. 5. Rostami-Hodjegan A, et al. Drug Dev Ind Pharm. 2022;28(5):523-531. 6. Atkinson HC, et al. J Bioequivalence & Bioavailab. 2015;7:3. 7. Tarabar S, et al. Drugs R D. 2020;20:23-37. 8. Nuromol Pain Relief 200 mg/500 mg Film Coated Tablets. Summary of Product Characteristics. Updated June 2022. Accessed January 2023. 9. Survey of Community Pharmacists Aug-Sep 2022. 10. Mehlisch D, et al. Clin Ther. 2010;32(5):882-895. 11. Mehlisch D, et al. Clin Ther. 2010;32(6):1033-1049.

Essential Information

Nuromol Pain Relief 200 mg/500 mg film coated tablets For the temporary relief of mild to moderate pain associated with migraine, headache, backache, period pain, dental pain, rheumatic and muscular pain, pain of non-serious arthritis, cold and flu symptoms, sore throat and fever. This product is especially suitable for pain which has not been relieved by ibuprofen or paracetamol alone. Nuromol Pain Relief 200mg/500mg Film Coated Tablets is indicated in adults aged 18 years. Licence Holder: Reckitt Benckiser Healthcare (UK) Limited, Slough, SL1 3UH. Legal Classification: P. Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at https://www.medicines.org.uk/emc/product/13804.

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard, or search for the MHRA Yellow Card in the Google Play or Apple App Store. Adverse events should also be reported to Reckitt Benckiser Healthcare (UK) ltd on: 0333 200 5345

RKT-M-09246 January 2022

for bacterial

and

Trust the UK’s first pharmacy-only OTC antibiotic2 Scientifically proven to help treat acute bacterial conjunctivitis Can help reduce the duration of moderate symptoms3

Ointment offers an alternative for adults & children who don’t like drops ... No need for refrigeration Suitable for both day & night time use

Experts in Eye Care

conjunctivitis. MA Holder: Optrex Limited, SL1 3UH. Information about this product, including

https://www.medicines.org.uk/emc/product/612/smpc Optrex Bacterial Conjunctivitis 1% w/w/ Eye Ointment: 110

TOOTHACHE RELIEF – STARTS IN UNDER

Orajel Extra strength contains Benzocaine. Always read the label.

Tummy Trouble? Relief is

Rennie® Peppermint (Calcium Carbonate 680mg and Magnesium Carbonate 80mg). Indications: For relief of indigestion and heartburn. MA Holder: Bayer plc, 400 South Oak Way, Reading, RG2 6AD, UK (information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at https://www. medicines.org.uk/emc/product/13863/smpc). Legal Category: GSL. Date of Preparation: March 2023. ® Registered trademark of Bayer AG. Neutralises 99% of excess stomach acid in 60 seconds

Senokot Max Strength Tablets 12 Years Plus: Each tablet contains powdered Alexandrian Senna fruit (pods) and Tinnevelly Senna fruit (pods) equivalent to 15mg hydroxyanthracene glycosides, calculated as sennoside B. Indications: For the short-term relief of occasional constipation. Legal Category: P. MA Holder: Reckitt Benckiser Healthcare (UK) Ltd, Hull, HU8 7DS. Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at: https://www.medicines.org.uk/emc/product/11549/smpc RT-M-4ubwux

LIFE’S TOO SHORT FOR SENSITIVE TEETH

Discover the science of Sensodyne Repair & Protect Deep Repair

With NovaMin technology

Clinically proven for long lasting* protection against dentine hypersensitivity

With twice daily brushing

Compared to a

FOR DAILY PROTECTION AGAINST DIETARY ACIDS

Unique formulation that is optimised for fluoride delivery

Actively strengthens acid softened enamel surfaces

Helps maintain high and longer-lasting levels of fluoride**

Learn more about the science behind Sensodyne and Pronamel toothpastes

Suitable for those who are unable to swallow

SUPERIOR PROTECTION

WITH SURPRISING DISCRETION

The UK’s No1 Bladder Weakness Brand*

Key Product Benefits:

The entire range provides long lasting dryness.

It’s designed to be safe and kind to the skin.

Offers the protection you’d expect from a TENA product.

Dermatologically tested and perfume free

TENA discreet effectively locks in moisture for up to 12 hours offering your customers superior protection day or night. 1 in 3 women experience bladder weakness at some point in their life. Help women find the right purpose-made product for their needs and provide your customers with protection that’s trusted by millions.

Source: Bladder Weakness RSV% by Brand and Sub-Brand - Nielsen data to 05.08.23

LET’S GET MEN COMFORTABLE SPEAKING ABOUT URINE LEAKAGE

Interdental cleaning is fundamental as a tool for maintaining a healthy smile. We offer a variety of interdental products for every person and type of gap.

• The user-friendly handle offers a stable grip which enables cleaning with controlled movements.

• The bristles cover the entire wire for safe and gentle cleaning.

• The smaller brush sizes (0-3) have a flexible neck for increased durability and access. The larger brush sizes have a thicker, bendable wire.

• Angled brush head for easier access, especially between the posterior teeth.

• Plastic coated wire for safe use.

• Long, flat handle for a stable grip.

• Easy and effective way to clean between the teeth.

• Overlapping, conical sizes to fit all interdental spaces.

• The unique lamellae allow for a wide contact area.

245-2910TEPE INTERDENTAL BRUSHES YELLOW 0.7MM 6

380-3939TEPE INTERDENTAL TOOTHBRUSHES ANGLE BLUE 0.6MM 6£2.65 15.00%£2.25 380-3954TEPE INTERDENTAL TOOTHBRUSHES ANGLE GREEN 0.8MM 6£2.65 15.00%£2.25 380-4549TEPE INTERDENTAL TOOTHBRUSHES ANGLE MIXED 6

380-4531TEPE INTERDENTAL TOOTHBRUSHES ANGLE ORANGE 0.45MM 6£2.65 15.00%£2.25 380-3913TEPE INTERDENTAL TOOTHBRUSHES ANGLE PINK 0.4MM 6£2.65 15.00%£2.25 380-3921TEPE INTERDENTAL TOOTHBRUSHES ANGLE RED 0.5MM 6£2.65 15.00%£2.25

380-3947TEPE INTERDENTAL TOOTHBRUSHES ANGLE YELLOW 0.7MM 6£2.65 15.00%£2.25

317-4422TEPE PLAQSEARCH 2-TONE DISCLOSING TABLETS 20 £2.70 15.00%£2.30

TRANSFER ORDER PRICE TRANSPARENCY

Sigma invoices will show both manufacturer and Sigma discounts per line.

SINGLES & OUTERS

For day to day buying, all products are available with a standard Sigma discount, irrespective of ordering a single or an outer.

MONTHLY PROMOTION BOOK

Includes a retail category management information booklet & lots of product information.

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