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PLOF October 2025

Page 1


Indications: For relief of symptoms of cold and flu with associated congestion, including aches and pains, headache, fever, sore throat, blocked nose and sinuses. Legal Category: P. MA Holder: Reckitt Benckiser Healthcare (UK) Ltd, Slough, SL1 4AQ. Information about this product, including adverse reactions, precautions, contraindications, and method of use, can be found at: http://www.medicines.org.uk/emc/product/5626/smpc. RT-M-q48KHm

1. Nurofen Cold and Flu. Summary of Product Characteristics. Updated March 2025. Accessed July 2025. Available at: Nurofen Cold and Flu - Summary of Product Characteristics (SmPC) - (emc) | 5626
NUROFEN COLD & FLU: Each tablet contains Ibuprofen 200mg and Pseudoephedrine Hydrochloride 30mg.

PAIN AND FEVER RELIEF FOR UP TO 8 HOURS1,2

Nothing

relieves fever for longer, day or night2

Starts to work in 15 minutes to reduce fever3 Has anti-inflammatory properties to help with sore throat1

Clinically proven to last longer than paracetamol in fever relief2

LEARN WHEN TO RECOMMEND

References: 1. Nurofen for Children Strawberry 3 months to 12 years. Oral Suspension. Summary of Product Characteristics. Updated February 2025. Accessed May 2025. Available at: https:// www. medicines.org.uk/emc/product/393/smpc. 2. Kelley, MT, et al. Clin Pharmacol Ther. 1992;52(2):181–189. 3. Pelen, F, et al. Ann Pediatr (Paris). 1998; 45(10):719–728.

ESSENTIAL INFORMATION

NUROFEN FOR CHILDREN STRAWBERRY 3 MONTHS TO 12 YEARS ORAL SUSPENSION: Ibuprofen 100 mg/5 ml (equivalent to 2.0% w/v). Legal Category: (P). Indications: For the fast and effective reduction of fever, including post immunisation pyrexia and the fast and effective relief of the symptoms of colds and influenza and mild to moderate pain, such as sore throat, teething pain, toothache, headache, minor aches and sprains. MA Holder: Reckitt Benckiser Healthcare (UK) Ltd, SL1 4AQ. Information about this product including adverse reactions, precautions, contra-indications and method of use can be found at https://www.medicines.org.uk/emc/product/393/smpc#gref Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov. uk/yellowcard or search for the MHRA Yellow Card in the Google Play or Apple App Store. Adverse events should also be reported to Reckitt Benckiser Healthcare (UK) ltd on: 0333 200 5345

SYMPTOMATIC

SORE THROAT 1–10 FOR BACTERIAL & VIRAL

FAST ACTING MEDICATED RELIEF 1

References: 1. McNally D, et al. Int J Clin Pract. 2010;64:194–207 2. Wade AG, et al. BMC Fam Pract. 2011;12:6. 3. Matthews D, et al. Int J Gen Med. 2018; 11:451–456. 4. Oxford JS, et al. Antivir Chem Chemother. 2005;16:129-134. 5. Shephard A, et al. Antiviral Res. 2015;123:158-162. 6. Morokutti-Kurz M, et al. Int J Gen Med. 2017;10:53–60. 7. Weckmann G, et al. Int. J Clin Pract. 2017;71(10) 8. EMC, electronic medicines compendium. Strepsils Honey & Lemon. Updated April 2021. Accessed June 2025. Available at https://www.medicines.org.uk/emc/product/5606 9. EMC, electronic medicines compendium. Strepsils Extra Triple Action Blackcurrant Lozenges. Updated August 2021. Accessed June 2025. Available at https://www.medicines.org.uk/emc/product/5601 10. EMC, electronic medicines compendium. Strepsils Sore Throat and Cough. Updated May 2021. Accessed June 2025. Available at https://www.medicines.org.uk/emc/product/8142

STREPSILS EXTRA TRIPLE ACTION BLACKCURRANT LOZENGES: Each lozenge contains hexylresorcinol 2.4 mg. Indications: An antiseptic and local anaesthetic for the relief of sore throat and its associated pain. Legal Category: GSL. MA Holder: Reckitt Benckiser Healthcare (UK) Ltd, Slough, SL1 3UH. Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at: https://www.medicines.org.uk/emc/product/5601/smpc.

STREPSILS HONEY AND LEMON: Each lozenge contains amylmetacresol (0.6 mg) and 2,4-dichlorobenzyl alcohol (1.2 mg). Indications: For the symptomatic relief of mouth and throat infections. Legal Category: GSL. MA Holder: Reckitt Benckiser Healthcare (UK) Ltd, Slough, SL1 3UH. Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at: https://www.medicines.org.uk/emc/product/5606/smpc

STREPSILS SORE THROAT AND COUGH: Each lozenge contains 2,4-dichlorobenzyl alcohol (1.2mg), amylmetacresol (0.6mg) and levomenthol (8.0mg). Indications: for the symptomatic relief of mouth and throat infections, dry, irritating cough associated with the common cold and nasal congestion. Legal Category: GSL. MA Holder: Reckitt Benckiser Healthcare (UK) Ltd, Slo9ugh, SL1 3UH. Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at https://www.medicines.org.uk/emc/product/8142/smpc

NOTHING STRONGER

FOR TARGETED RELIEF OF PAINFUL SORE THROAT1-5

Recommend Strefen - tackles the pain of bacterial and viral sore throats 1-4,6,7

References: 1. Strefen Direct Cherry and Mint Flavour 8.75mg Oromucosal Spray. Summary of Product Characteristics. August 2024. Accessed July 2025. Available at: https:// www.medicines.org.uk/emc/product/15868/smpc. 2. Strefen Honey and Lemon. Summary of Product Characteristics. Updated November 2023. Accessed July 2025. Available at: https://www.medicines.org.uk/emc/product/6514/smpc. 3. Strefen Eucalyptus and Manuka Honey. Summary of Product Characteristics. Updated July 2024. Accessed July 2025. Available at: https://www.medicines.org.uk/emc/product/15831/smpc. 4. Strefen Orange Flavour Sugar Free 8.75mg Lozenges. Summary of Product Characteristics. Updated January 2025. Accessed July 2025. Available at: https://www.medicines.org.uk/emc/product/100409/smpc. 5. Data on file, Reckitt. 6. Blagden M, et al. Int J Clin Pract. 2002; 58:95–100. 7. Shephard A et al. Abstract presented at the European Congress of Clinical Microbiology and Infectious Diseases, 27–30 April 2013, Berlin, Germany.

ESSENTIAL INFORMATION:

STREFEN DIRECT CHERRY AND MINT FLAVOUR 8.75MG OROMUCOSAL SPRAY: One actuation contains 2.92 mg of Flurbiprofen, three actuations equal to one dose contains 8.75mg, corresponding to 16.2 mg/ml Flurbiprofen. Indications: For the short term symptomatic relief of acute sore throat in adults. Legal Category: P. MA Holder: Reckitt Benckiser Healthcare (UK) Ltd, Slough, SL1 3UH. Information about this product, including adverse reactions, precautions, contraindications, and method of use can be found at: https://www.medicines.org.uk/emc/product/15868/smpc.

STREFEN HONEY AND LEMON & STREFEN EUCALYPTUS AND MANUKA HONEY FLAVOUR 8.75MG LOZENGES & STREFEN ORANGE FLAVOUR SUGAR FREE 8.75MG LOZENGES: Each lozenge contains flurbiprofen 8.75mg. Indications: For the short term symptomatic relief of sore throat in adults and children over the age of 12 years. Legal Category: P. MA Holder: Reckitt Benckiser Healthcare (UK) Ltd, Slough, SL1 3UH. Information about this product, including adverse reactions, precautions, contraindications, and method of use can be found at: https://www.medicines.org.uk/ emc/product/6514 and https://www.medicines.org.uk/emc/product/15831/smpc and https://www.medicines.org.uk/emc/product/100409/smpc.

References: 1. EMC, electronic medicines compendium. Lemsip Max Cold & Flu Lemon. Updated March 2025. Accessed June 2025. Available at https://www.medicines.org.uk/emc/product/5612/smpc 2. EMC, electronic medicines compendium. Lemsip Max Cold & Flu Capsules. Updated March 2025. Accessed June 2025. Available at https://www.medicines.org.uk/emc/product/5617/smpc.

LEMSIP MAX COLD & FLU LEMON: Each powder sachet contains Paracetamol 1000mg, Phenylephrine Hydrochloride 12.2mg. Indications: For relief of the symptoms of colds and influenza, including the relief of aches and pains, sore throat, headache, nasal congestion and lowering of temperature. Legal Category: GSL. MA Holder: Reckitt Benckiser Healthcare (UK) Ltd, Hull, HU8 7DS. Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at: https://www.medicines.org.uk/emc/product/5612/smpc

LEMSIP MAX COLD & FLU CAPSULES: Each capsule contains Paracetamol 500mg, Caffeine 25mg, Phenylephrine Hydrochloride 6.1mg.

Indications: For the relief of symptoms associated with the common cold and influenza, including relief of aches and pains, sore throat, headache, fatigue and drowsiness, nasal congestion, and lowering of temperature. Legal Category: GSL. MA Holder: Reckitt Benckiser Healthcare (UK) Ltd, Hull, HU8 7DS. Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at: https://www.medicines.org.uk/emc/ product/5617/smpc

The UK’s #1 BV Treatment*

How Balance Activ® BV Treatment Gel and Pessaries works:

Not a drug: Mimics the vagina’s own defence mechanism to treat and relieve BV, naturally.

Reliable: Clinically proven to work, for a dependable natural alternative.

Effective: Replenishes the body’s natural lactic acid to restore the vagina’s normal pH, rapidly relieving symptoms.

Balance: Tops up glycogen to encourage good bacteria and maintain pH balance to keep BV at bay.

Convenient: Comes with 7 single-use, gel-filled tubes –a week’s treatment – for easy and hygienic application.

*Source: Nielsen GB Total Coverage – Unit Sales - WE 4 June 2024

The naturally working treatment for Bacterial Vaginosis: Available in 2 easy to use formatspessary & gel for added convenience. +

Balance Activ Thrush Cream is not a drug, but a treatment with 3 benefits designed to help the body fight the cause, relieve the symptoms, and prevent the recurrence of thrush.

Thrush Cream

How Balance Activ® Thrush Cream works:

Not a drug: 3 benefits in 1 treatment to help the body fight the cause, treat the symptoms, and prevent thrush.

Protects: Restricts the growth of harmful bacteria, allowing the body to fight the cause.

Relieves: Provides relief from intimate itching, redness, and soreness.

Prevents: Retores and maintains a balanced vaginal pH and flora to prevent thrush from recurring.

Simple: No fragrance and paraben added.

Convenient: Includes 5 single-use applicators for easy insertion. Can also be used externally.

NOTHING STRONGER

FOR TARGETED RELIEF OF PAINFUL SORE THROAT1-5

References: 1. Strefen Direct Cherry and Mint Flavour 8.75mg Oromucosal Spray. Summary of Product Characteristics. August 2024. Accessed July 2025. Available at: https:// www.medicines.org.uk/emc/product/15868/smpc. 2. Strefen Honey and Lemon. Summary of Product Characteristics. Updated November 2023. Accessed July 2025. Available at: https://www.medicines.org.uk/emc/product/6514/smpc. 3. Strefen Eucalyptus and Manuka Honey. Summary of Product Characteristics. Updated July 2024. Accessed July 2025. Available at: https://www.medicines.org.uk/emc/product/15831/smpc. 4. Strefen Orange Flavour Sugar Free 8.75mg Lozenges. Summary of Product Characteristics. Updated January 2025. Accessed July 2025. Available at: https://www.medicines.org.uk/emc/product/100409/smpc. 5. Data on file, Reckitt. 6. Blagden M, et al. Int J Clin Pract. 2002; 58:95–100. 7. Shephard A et al. Abstract presented at the European Congress of Clinical Microbiology and Infectious Diseases, 27–30 April 2013, Berlin, Germany.

ESSENTIAL INFORMATION:

STREFEN DIRECT CHERRY AND MINT FLAVOUR 8.75MG OROMUCOSAL SPRAY: One actuation contains 2.92 mg of Flurbiprofen, three actuations equal to one dose contains 8.75mg, corresponding to 16.2 mg/ml Flurbiprofen. Indications: For the short term symptomatic relief of acute sore throat in adults. Legal Category: P. MA Holder: Reckitt Benckiser Healthcare (UK) Ltd, Slough, SL1 3UH. Information about this product, including adverse reactions, precautions, contraindications, and method of use can be found at: https://www.medicines.org.uk/emc/product/15868/smpc.

STREFEN HONEY AND LEMON & STREFEN EUCALYPTUS AND MANUKA HONEY FLAVOUR 8.75MG LOZENGES & STREFEN ORANGE FLAVOUR SUGAR FREE 8.75MG LOZENGES: Each lozenge contains flurbiprofen 8.75mg. Indications: For the short term symptomatic relief of sore throat in adults and children over the age of 12 years. Legal Category: P. MA Holder: Reckitt Benckiser Healthcare (UK) Ltd, Slough, SL1 3UH. Information about this product, including adverse reactions, precautions, contraindications, and method of use can be found at: https://www.medicines.org.uk/ emc/product/6514 and https://www.medicines.org.uk/emc/product/15831/smpc and https://www.medicines.org.uk/emc/product/100409/smpc. RT-M-fa9uJ3 July 2025 Recommend Strefen - tackles the pain of bacterial and viral sore throats 1-4,6,7

Retail Category Management

October

Guidance and product information for OTC brands and categories to help support the pharmacy team.

See this month’s book for offers on products featured in the

SYMPTOMATIC

SORE THROAT 1–10

FAST ACTING MEDICATED RELIEF 1

References: 1. McNally D, et al. Int J Clin Pract. 2010;64:194–207 2. Wade AG, et al. BMC Fam Pract. 2011;12:6. 3. Matthews D, et al. Int J Gen Med. 2018; 11:451–456. 4. Oxford JS, et al. Antivir Chem Chemother. 2005;16:129-134. 5. Shephard A, et al. Antiviral Res. 2015;123:158-162. 6. Morokutti-Kurz M, et al. Int J Gen Med. 2017;10:53–60. 7. Weckmann G, et al. Int. J Clin Pract. 2017;71(10) 8. EMC, electronic medicines compendium. Strepsils Honey & Lemon. Updated April 2021. Accessed June 2025. Available at https://www.medicines.org.uk/emc/product/5606 9. EMC, electronic medicines compendium. Strepsils Extra Triple Action Blackcurrant Lozenges. Updated August 2021. Accessed June 2025. Available at https://www.medicines.org.uk/emc/product/5601 10. EMC, electronic medicines compendium. Strepsils Sore Throat and Cough. Updated May 2021. Accessed June 2025. Available at https://www.medicines.org.uk/emc/product/8142

STREPSILS EXTRA TRIPLE ACTION BLACKCURRANT LOZENGES: Each lozenge contains hexylresorcinol 2.4 mg.

Indications: An antiseptic and local anaesthetic for the relief of sore throat and its associated pain. Legal Category: GSL. MA Holder: Reckitt Benckiser Healthcare (UK) Ltd, Slough, SL1 3UH. Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at: https://www.medicines.org.uk/emc/product/5601/smpc.

STREPSILS HONEY AND LEMON: Each lozenge contains amylmetacresol (0.6 mg) and 2,4-dichlorobenzyl alcohol (1.2 mg). Indications: For the symptomatic relief of mouth and throat infections. Legal Category: GSL. MA Holder: Reckitt Benckiser Healthcare (UK) Ltd, Slough, SL1 3UH. Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at: https://www.medicines.org.uk/emc/product/5606/smpc

STREPSILS SORE THROAT AND COUGH: Each lozenge contains 2,4-dichlorobenzyl alcohol (1.2mg), amylmetacresol (0.6mg) and levomenthol (8.0mg). Indications: for the symptomatic relief of mouth and throat infections, dry, irritating cough associated with the common cold and nasal congestion. Legal Category: GSL. MA Holder: Reckitt Benckiser Healthcare (UK) Ltd, Slo9ugh, SL1 3UH. Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at https://www.medicines.org.uk/emc/product/8142/smpc

19.06.25. RT-M-BtVq1A Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard, or search for the MHRA Yellow Card in the Google Play or Apple App Store. Adverse events should also be reported to Reckitt Benckiser Healthcare (UK) ltd on: 0333 200

References: 1. EMC, electronic medicines compendium. Lemsip Max Cold & Flu Lemon. Updated March 2025. Accessed June 2025. Available at https://www.medicines.org.uk/emc/product/5612/smpc 2. EMC, electronic medicines compendium. Lemsip Max Cold & Flu Capsules. Updated March 2025. Accessed June 2025. Available at https://www.medicines.org.uk/emc/product/5617/smpc.

LEMSIP MAX COLD & FLU LEMON: Each powder sachet contains Paracetamol 1000mg, Phenylephrine Hydrochloride 12.2mg.

Indications: For relief of the symptoms of colds and influenza, including the relief of aches and pains, sore throat, headache, nasal congestion and lowering of temperature. Legal Category: GSL. MA Holder: Reckitt Benckiser Healthcare (UK) Ltd, Hull, HU8 7DS. Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at: https://www.medicines.org.uk/emc/product/5612/smpc

LEMSIP MAX COLD & FLU CAPSULES: Each capsule contains Paracetamol 500mg, Caffeine 25mg, Phenylephrine Hydrochloride 6.1mg.

Indications: For the relief of symptoms associated with the common cold and influenza, including relief of aches and pains, sore throat, headache, fatigue and drowsiness, nasal congestion, and lowering of temperature. Legal Category: GSL. MA Holder: Reckitt Benckiser Healthcare (UK) Ltd, Hull, HU8 7DS. Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at: https://www.medicines.org.uk/emc/ product/5617/smpc

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard, or search for the MHRA Yellow Card in the Google Play or Apple App Store. Adverse events should also be reported to Reckitt Benckiser Healthcare (UK) ltd on: 0333 200 5345

Produced 27.06.25. RT-M-yIGBXB

PAIN AND FEVER RELIEF FOR UP TO 8 HOURS1,2

Nothing relieves fever for longer, day or night2

Starts to work in 15 minutes to reduce fever3

Clinically proven to last longer than paracetamol in fever relief2

Has anti-inflammatory properties to help with sore throat1

LEARN WHEN TO RECOMMEND

References: 1. Nurofen for Children Strawberry 3 months to 12 years. Oral Suspension. Summary of Product Characteristics. Updated February 2025. Accessed May 2025. Available at: https:// www. medicines.org.uk/emc/product/393/smpc. 2. Kelley, MT, etal.ClinPharmacolTher. 1992;52(2):181–189. 3. Pelen, F, et al. Ann Pediatr (Paris). 1998; 45(10):719–728.

ESSENTIAL INFORMATION

NUROFEN FOR CHILDREN STRAWBERRY 3 MONTHS TO 12 YEARS ORAL SUSPENSION: Ibuprofen 100 mg/5 ml (equivalent to 2.0% w/v). Legal Category: (P). Indications: For the fast and effective reduction of fever, including post immunisation pyrexia and the fast and effective relief of the symptoms of colds and influenza and mild to moderate pain, such as sore throat, teething pain, toothache, headache, minor aches and sprains. MA Holder: Reckitt Benckiser Healthcare (UK) Ltd, SL1 4AQ. Information about this product including adverse reactions, precautions, contra-indications and method of use can be found at https://www.medicines.org.uk/emc/product/393/smpc#gref

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov. uk/yellowcard or search for the MHRA Yellow Card in the Google Play or Apple App Store. Adverse events should also be reported to Reckitt Benckiser Healthcare (UK) ltd on: 0333 200 5345

1. Nurofen Cold and Flu. Summary of Product Characteristics. Updated March 2025. Accessed July 2025. Available at: Nurofen Cold and Flu - Summary of Product Characteristics (SmPC) - (emc) | 5626

NUROFEN COLD & FLU: Each tablet contains Ibuprofen 200mg and Pseudoephedrine Hydrochloride 30mg.

Indications: For relief of symptoms of cold and flu with associated congestion, including aches and pains, headache, fever, sore throat, blocked nose and sinuses. Legal Category: P. MA Holder: Reckitt Benckiser Healthcare (UK) Ltd, Slough, SL1 4AQ. Information about this product, including adverse reactions, precautions, contraindications, and method of use, can be found at: http://www.medicines.org.uk/emc/product/5626/smpc. RT-M-q48KHm

NOTHING STRONGER

FOR TARGETED RELIEF OF PAINFUL SORE THROAT1-5

References: 1. Strefen Direct Cherry and Mint Flavour 8.75mg Oromucosal Spray. Summary of Product Characteristics. August 2024. Accessed July 2025. Available at: https:// www.medicines.org.uk/emc/product/15868/smpc. 2. Strefen Honey and Lemon. Summary of Product Characteristics. Updated November 2023. Accessed July 2025. Available at: https://www.medicines.org.uk/emc/product/6514/smpc. 3. Strefen Eucalyptus and Manuka Honey. Summary of Product Characteristics. Updated July 2024. Accessed July 2025. Available at: https://www.medicines.org.uk/emc/product/15831/smpc. 4. Strefen Orange Flavour Sugar Free 8.75mg Lozenges. Summary of Product Characteristics.

Updated January 2025. Accessed July 2025. Available at: https://www.medicines.org.uk/emc/product/100409/smpc. 5. Data on file, Reckitt. 6. Blagden M, et al. Int J Clin Pract. 2002; 58:95–100. 7. Shephard A et al. Abstract presented at the European Congress of Clinical Microbiology and Infectious Diseases, 27–30 April 2013, Berlin, Germany.

ESSENTIAL INFORMATION:

STREFEN DIRECT CHERRY AND MINT FLAVOUR 8.75MG OROMUCOSAL SPRAY: One actuation contains 2.92 mg of Flurbiprofen, three actuations equal to one dose contains 8.75mg, corresponding to 16.2 mg/ml Flurbiprofen. Indications: For the short term symptomatic relief of acute sore throat in adults. Legal Category: P. MA Holder: Reckitt Benckiser Healthcare (UK) Ltd, Slough, SL1 3UH. Information about this product, including adverse reactions, precautions, contraindications, and method of use can be found at: https://www.medicines.org.uk/emc/product/15868/smpc.

FLAVOUR 8.75MG LOZENGES & STREFEN ORANGE FLAVOUR SUGAR FREE 8.75MG LOZENGES: Each lozenge contains flurbiprofen 8.75mg. Indications: For the short term symptomatic relief of sore throat in adults and children over the age of 12 years. Legal Category: P. MA Holder: Reckitt Benckiser Healthcare (UK) Ltd, Slough, SL1 3UH. Information about this product, including adverse reactions, precautions, contraindications, and method of use can be found at: https://www.medicines.org.uk/ emc/product/6514 and https://www.medicines.org.uk/emc/product/15831/smpc and https://www.medicines.org.uk/emc/product/100409/smpc. RT-M-fa9uJ3 July 2025 Recommend Strefen - tackles the pain of bacterial and viral sore throats 1-4,6,7 From the makers of

STREFEN HONEY AND LEMON & STREFEN EUCALYPTUS AND MANUKA HONEY

& THE EXPERT RECOMMENDED

3 STEP REGIME

Experts recommend a regimen including lubricants, lid hygiene and heat applied to the eyes for the management of Dry Eye Disease and related eye conditions such as Blepharitis and Meibomian Gland Dysfunction.

OPTASE® MOIST HEAT MASK

A reusable mask that heats the oil glands in the eyelids to help release the natural oils and allow them to spread across the surface of the eye.

OPTASE® TTO EYELID CLEANSING GEL

Can be used to cleanse the eyelids and remove any stubborn scruff or debris.

HYCOSAN® EYE DROPS

Preservative Free eye drops with Long Chain HA to soothe, hydrate and replenish the tear film.

High quality, market leading products for the management of dry eye, blepharitis and MGD.

A gentle and preservative free, tea tree oil based lid wipe for daily eyelid hygiene.

100% Preservative Free

Plastic Free, Biodegradable Wipes

Pro-vitamin B5 has Significant Moisturising Properties

2 Months Supply

For more information visit Scopeeyecare.com E: info@scopeeyecare.com T:

The role of OTC Omeprazole Tablets 20mg in the Pharmacy

Omeprazole 20mg is a key active ingredient that you will be familiar with on prescription and which is available for customers to purchase OTC.

Learning Outcomes:

Know how omeprazole works

Understand who can purchase OTC omeprazole 20mg

Be able to give additional lifestyle advice to customers

Be able to talk to GPs confidently about this opportunity

An opportunity for:

Customers

How Omeprazole works

To recommend an effective product for heartburn and acid reflux, the same strength as the prescription product.

You (Pharmacists)

To purchase an active ingredient they are familiar with – omeprazole 20mg.

To recognise the expertise of the pharmacy team to advise them on heartburn and acid reflux.

GPs

To refer customers to the pharmacy to purchase omeprazole 20mg to support the self-care agenda.

Symptoms of heartburn and acid reflux can be relieved by reducing the acidity of the stomach, which can be done through reducing or neutralising the acid. Omeprazole is a proton pump inhibitor (PPI) that acts to reduce the amount of acid produced in the stomach by blocking the proton pump of the cells in the stomach. (These produce the hydrogen used in the formation of the hydrochloric acid that causes the symptoms.)

Pharmacy expertise

By completing this training and the online module, the pharmacy team can make sure they feel confident to recommend the product and recognise when customers should be referred.

Supporting self-care

Heartburn has been identified as a condition suitable for self-care. GPs have been advised not to prescribe for short-term symptoms as patients can be given lifestyle advice and purchase effective products from their pharmacy to relieve their symptoms.

How

and when to use

Pyrocalm

Control tablets (Omeprazole 20mg)

Pyrocalm Control Tablets (Omeprazole 20mg) can be used for the treatment of reflux symptoms.1 These include heartburn and acid reflux (when the acid from the stomach travels up to the throat).

Customers may describe having a burning sensation in their chest or an acidic taste in the mouth.2 They may notice that the symptoms are worse after eating, and when lying down or bending forward. They may also get recurrent hiccups, a hoarse voice, queasiness, halitosis or a bloated sensation.

For adults over 18 years of age

Available as a two-week supply

Directions for use:

One tablet in the morning, swallowed whole, with a glass of water

Take until symptoms have resolved (up to 14 days use only)

Can be taken with or without food

One table provides relief for up to 24 hours

Long-lasting effect

Strongest dose available OTC

IMPORTANT: It can take two to three days to achieve symptom improvement. Customers can use antacids for their symptoms while waiting for the product to have full effect.

Interactions / Cautions:

Pyrocalm Control Tablets (Omeprazole 20mg) shouldn’t be taken by customers who are using other PPIs or H2-antagonists (e.g. ranitidine). It interacts with nelfinavir. Customers with any allergies to the ingredients or previous sensitivities to other PPIs shouldn’t take Pyrocalm Control Tablets (Omeprazole 20mg). Remind customers to read the leaflet as there are other medicines that may interact. Customers taking other medicines (including herbal/supplements) should discuss these with the pharmacist.

When to refer:

A key concern is that taking omeprazole 20mg might mask the signs of something else that needs further investigation, such as a peptic ulcer or cancer.

The following should be referred to the pharmacist/GP:3

› Customers over 55 who are experiencing: symptoms for the first time; worsening symptoms; persistent symptoms; or symptoms that don’t improve with medication.

Symptoms that require referral include:

› Unexplained weight loss

› Difficulty swallowing

› Stomach pain/signs of indigestion, especially after food intake

› Blood in the vomit, or dark blood (like coffee granules) in vomit

› Black stools

› Persistent symptoms for more than four weeks.

Additional self-care advice:2

The following advice can help customers to manage their symptoms.

› Try to avoid trigger foods e.g. fatty foods, chocolate

› Avoid drinks such as coffee, alcohol and fizzy drinks

› Eat smaller portions and eat slowly, particularly avoiding large meals less than three hours before bed

› Raising the head-end of the bed at night by putting something under the mattress may help with nighttime symptoms

› Wear clothes that are loose around the waist

› If overweight, losing weight may help

› Smokers can be advised to try stopping smoking.

It may also be helpful to check whether the customer has been taking non-steroidal anti-inflammatories (NSAIDs), as these can cause symptoms. You can discuss their use, and if appropriate recommend reducing the dose and trying omeprazole 20mg.

Frequently Asked Questions

Can pyrocalm control tablets (Omeprazole 20mg) be taken by pregnant women?

It can, as it is not known to be harmful,4 but customers may want to consult with their GP first.

Will GPs ask their patients to buy this?

Yes – in some cases customers may present with a referral form from their GP recommending that they purchase omeprazole 20mg.

Are there any side effects?

As with all medicines, there are potential side effects. Any new side effects should be recorded using the Yellow Card Scheme at www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.

Common side effects include headache, abdominal pain, constipation, diarrhoea, flatulence and nausea/ vomiting. Rare, but serious, signs to be aware of are: allergy, reddening of the skin and peeling (potentially Stevens- Johnson syndrome), yellowing skin/dark urine indicating liver problems, bruising/severely reduced general condition and fever (indicating changes in white blood cells).

Where in the pharmacy can customers find the product?

Customers can self-select this product from pharmacies as it is GSL, but your role in giving advice on product use, self-care and being aware of symptoms to refer is crucial.

My local GPs often prescribe this. Shall I tell them about its OTC availability?

Definitely. GPs can refer customers to your pharmacy to purchase the product if appropriate. This offers an opportunity to talk to your local GPs about who they might refer to purchase, whether they would expect any followup, and what kinds of customers they would rather were referred to the surgery instead of trying self-treatment.

What if it doesn’t work for a customer?

If they have only taken it for a short time, remind them that it can take two to three days to have full effect. If they are getting breakthrough symptoms, they can use an antacid. If they have been using it for two weeks with no effect, they should see their GP.

Further information

For further information about treating heartburn and acid reflux in the pharmacy, and customer scenarios to put your knowledge into practice, scan the QR code to view a short e-learning module online at Pharmacy Magazine.

Self test:

1. What is the strength of omeprazole in Pyrocalm Control?

A: 10mg

Pharmacy Professionals - you can use this learning as part of your revalidation.

Essential Product Information

2. How many days can it take to have full effect?

A: One to two

B: 20mg B: Two to three

3. Who of the following should be referred?

A: Customers over 55 who are experiencing symptoms for the first time.

B: Customers over 40 who are experiencing symptoms for the first time.

4. True or False:

Customers can be advised to eat slowly, avoid having a main meal within three hours of bedtime and raise the head of the bed at night to help reduce symptoms.

Pyrocalm Control® 20mg Gastro-Resistant Tablets Pharmaceutical form: Gastro-resistant tablets. Indications: For the short-term treatment of reflux symptoms in adults. Active ingredient: Omeprazole. Posology: Once daily for up to 14 days. Discontinue treatment once complete relief of symptoms has occurred. The majority of patients achieve complete relief of heartburn within 7 days. Method of administration: Take one tablet in the morning, swallowed whole with half a glass of water. Do not chew or crush the tablets. Contraindications: Children under 18 years; Hypersensitivity to the active substance, substituted benzimidazoles or to any of the excipients; nelfinavir. Special warnings and precautions for use: In the presence of any alarm symptom (e.g. significant unintentional weight loss, recurrent vomiting, dysphagia, haematemesis or melena) and when gastric ulcer is suspected or present, malignancy should be excluded. It is not recommended to co-administrate with atazanavir. Do not use concomitantly with clopidogrel. The tablets contain lactose therefore patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine. Treatment may lead to slightly increased risk of gastrointestinal infections such as Salmonella and Campylobacter and, in hospitalised patients, possibly also Clostridium difficile. Consult the doctor in the following conditions: previous gastric ulcer or gastrointestinal surgery; continuous symptomatic treatment of indigestion or heartburn for 4 or more weeks; jaundice or severe liver disease; aged over 55 years with new or recently changed symptoms of indigestion or heartburn. Do not take as a preventative medication. Do not take another PPI or H2 antagonist concomitantly. Seek medical help promptly if lesions occur, especially in sun-exposed areas of the skin, and if accompanied by arthralgia. This might associate with very infrequent cases of SCLE (Subacute cutaneous lupus erythematosus). Stop using for at least 5 days before CgA measurements in laboratory test. Increased CgA level may interfere with investigations for neuroendocrine tumours. Consult your doctor before taking this medicinal product if you are due to have an endoscopy or urea breath test. Omeprazole may reduce the absorption of vitamin B12 (cyanocobalamin) in patients with risk factors. Interaction with other medicinal products and other forms of interaction: atazanavir, digoxin, clopidogrel, posaconazole, erlotinib, ketoconazole, itraconazole, saquinavir, ritonavir, tacrolimus, methotrexate. Active substances metabolised by CYP2C19 such as: vitamin K antagonists (R-warfarin, cilostazol, phenytoin and diazepam). Active substances known to inhibit CYP2C19 or CYP3A4 (such as clarithromycin and voriconazole). Active substances known to induce CYP2C19 or CYP3A4 or both (such as rifampicin and St John’s wort). Concomitant administration of omeprazole with nelfinavir is contraindicated. Use during pregnancy and lactation: can be used during pregnancy and breastfeeding. Effects on ability to drive and use machines: None expected. Adverse drug reactions such as dizziness and visual disturbances may occur. If affected, patients should not drive or operate machinery. Side effects: The most common side effects (1-10% of patients) are headache, abdominal pain, constipation, diarrhoea, flatulence and nausea/vomiting. Another common side effect is fundic gland polyps (benign). Uncommon side effects: Insomnia, dizziness, paraesthesia, somnolence, vertigo, increased liver enzymes, dermatitis, pruritus, rash, urticarial, malaise and peripheral oedema. Rare side effects: Hypersensitivity reactions e.g. fever, angioedema and anaphylactic reaction/shock; leukopenia, thrombocytopenia, hyponatraemia, agitation, confusion, depression, taste disturbance, blurred vision, bronchospasm, dry mouth, stomatitis, gastrointestinal candidiasis, microscopic colitis, hepatitis with or without jaundice, alopecia, photosensitivity, arthralgia, myalgia, interstitial nephritis, increased sweating. Very rare side effects: agranulocytosis, pancytopenia, hypomagnesaemia, aggression, hallucinations, hepatic failure, encephalopathy in patients with preexisting liver disease, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis (TEN), muscular weakness, gynaecomastia. Side effect with ‘Not known’ frequency: Subacute cutaneous lupus erythematosus. Legal Category: GSL. Price: 7 Tablets £5.83, exc. VAT, 14 Tablets £9.16 exc. VAT Product licence number and holder: PL 14017/0277 Dexcel® Pharma Ltd., 7 Sopwith Way, Drayton Fields, Daventry, UK. Date of preparation: October 2019. Pyrocalm Control Tablets is a registered trademark.

References:

1. Pyrocalm Control® 20mg Gastro-Resistant Tablets SPC 2. https://www.nhs.uk/conditions/heartburn-and-acid-reflux/ 3. https://www.nice.org.uk/guidance/qs96/ chapter/Qualitystatement-1-Advice-to-support-selfmanagement 4. BNF 77. BMA/Royal Pharmaceutical Society. Online references last accessed March 2024.

No part of this publication may be reproduced without the written permission of the publishers, Dexcel Pharma in association with CIG Healthcare Partnership. ©2019 CIG Healthcare Partnership UK/2019-0451 Oct 2019.

This communication has been approved by the NPA. The NPA will have no liability to any person or entity with liability, loss or damage caused or alleged to have been caused directly or indirectly by information therein. The NPA is not responsible for the content of any non-NPA websites mentioned in this programme or for the accuracy of any information found there. The fact that a website, organisation or product is mentioned in the programme does not mean that the NPA either approves of it or endorses it.

Answers: 1 B, 2 B, 3 A, 4 True

Cough & Cold in Adults?

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Promote nasal decongestion.

Useful in colds, allergic rhinitis and mild rhinosinusitis.

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Summary of Terms

1. Where accounts have been approved for credit, payments are due 30 days from the month of invoice. Sigma Pharmaceuticals Plc reserves the right to charge interest on overdue accounts at the rate of 4% above the LIBOR (London InterBank Offered Rate) per month without prejudice to the right of recovery. Cheques payable to Sigma Pharmaceuticals Plc. Sigma Pharmaceuticals Plc reserves the right not to process the orders in case of an overdue account.

2. All orders and prices quoted are subject to the standard rate or reduced rate of V.A.T. on the NETT invoice value. The invoice date is the tax point for V.A.T. purposes.

3. Products on offer in the PLOF are not eligible for any further discounts.

4. All delivery enquiries must be notified within 24 hours of delivery

5. Prices are correct at time of going to print, but are subject to change without prior notice. Sigma Pharmaceuticals Plc reserves the right to amend any of their prices without due notice. Orders are accepted on condition that the goods will be invoiced at the prices ruling at the date of delivery. All images shown are for illustrative purposes only.

6. Invoice queries must be raised within one week of invoice date.

7. The goods shall remain the sole and absolute property of the seller and legal equitable owner until such time as the buyer shall have paid to the seller the agreed price together with the full price of any other contract with the seller.

8. Standard terms and conditions apply, as per trading terms, available upon request.

9. RSP’s shown are supplied by the manufacturers and are correct at time of going to print. It is at the retailers discretion to set their own retail price and margin.

Claims and Returns

DELIVERIES

When accepting your delivery please ensure the number of boxes/bulk received match the drivers runsheet and that any discrepancies are clearly marked. Non-delivery must be notified to Sigma Pharmaceuticals Plc within 1 service day of invoice date or advice of despatch.

RETURNS

Under existing rules and regulations issued by the DHSS and as published in “MAIL”, goods will only be accepted for return by Sigma Pharmaceuticals Plc for the following reasons:

• To correct an error in delivery or ordering.

• In response to a product or batch recall instigated by a manufacturer.

• Where products or packages are alleged to be faulty.

In order to be considered for credit or replacement the goods must be accompanied by a note showing:-

• The name and address of the customer returning the goods.

• The quantity and description of the goods.

• The invoice number on which the goods were supplied.

• The reason of the return.

Transfer Order Queries

Call 01923 331 411 and ask for the Transfer Order Department.

Expiry Date Queries

Dates on products should be checked upon delivery. If you wish to return an item due to the date, please follow the return procedure mentioned previously.

Items Missing From Delivery

Call 01923 444 999 within 24 hours of delivery.

Wrong Item Supplied

Mark the required item with the code of ‘B’ on your invoice/return slip.

Goods Ordered in Error

Mark the item with the code of ‘H’ on your invoice/return slip.

Goods Arrived Damaged

Mark the item with the code of ‘F’ on your invoice/return slip.

Recall Stock

All recall stock must be written on a return slip with the date, quantity and reason code K.

OTC & HEALTH AND BEAUTY TRANSFER ORDER OVERVIEW

Sigma offers a comprehensive transfer order service offering prompt deliveries, transparent invoicing and full advantage of manufacturers multi-level discounts (MLD) across a wide range of manufacturers.

WHY USE SICMA FOR TRANSFER ORDERS?

Our transparent invoice structure, quick turnaround and dedicated customer service means we are the preferred choice with manufacturers and third-party sales teams for transfer orders. Advantages of putting your transfer orders through Sigma:

> A minimum of 10% wholesaler discount on transfer orders)(-.

> Transparent discount structure

> More than 95% of products are available to order in singles

> Aim to deliver stock within 48 hours from receipt

> Back orders held for 60 days

> Dedicated transfer order team that can be directly contacted by telephone or email.

> Committed to ensure transfer order queries are resolved within 72 hours "Ethical and Rx Lines may not qualify for this discount

TRANSFER ORDER PORTFOLIO

BAYER

BIOKULT

•Alka Seltzer

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CLAXO SMITH l{LINE

CIGA HEALTHCARE

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·ORS

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BE T TERYOU

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BIOl{ULT

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BR PHARMACEU TICALS

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CARE FOR YOURSELF LTD

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CEU TA HEALTHCARE

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Aquafresh

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Beechams

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Breathe Right

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Corsodyl

Nurses

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Enos

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Eumovate

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CHURCH AND DWICHT

Nicotinell

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Poligrip

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CICA HEALTHCARE

ETHICOE

• Balance Activ

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·Lift

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·CBl2

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· lglu

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Cialis Together

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Dulco Range

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Maalox

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Nasacort

Opticrom

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Pharmaton

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Phenergan

Clearblue

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Fixodent

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Deep Freeze / Heat / Relief

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Mentholatum Ibuprofen

Mentholatum Vapour Rub

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Elastoplast

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Just For Men

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Cepton

Dalvit

l{ARIUM LTD

Dentinox

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LASER HEALTHCARE

Difflam

Ricola

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Dextro

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Doublebase

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· Nitty Gritty

PERRIGO (Omega Pharma)

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Bio-Oil

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RECKITT BENCKISER

Bonjela

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Veet

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THE MILES GROUP

A L Simpkin

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Colgate Palmolive

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Omron

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THEA PHARMACEUTICALS

Blephaclean

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Care

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Flexitol

Fultium

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Metanium

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Mycota

Oilatum

Radian B

Savlon

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Virasorb

Virasoothe

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Zeroderm

Tel: 0800 597 4462, Option 3

Email: cs@sigmaplc.com

Email: rushin@sigmaplc.com

Tel: 0800 597 4462, Option 3

Email: hitesh@sigmaplc.com

Sharon Walker, Customer Services Manager

Tel: 0800 358 4427

Michelle Sparrow, Business Development Manager

Email: cs@sigmaplc.com

Tel: 01923 332 790

Dipesh Vaja, Head of Sales

Tel: 0800 597 4462

Email: michelle@sigmaplc.com

The sales team supporting you at Sigma

Head of Sales

The sales team supporting you at Sigma

Email: dipesh@sigmaplc.com

Business Development

Telesales/Customer Service Head of Sales

Dipesh Vaja, Head of Sales

Sales Executives

Dipesh Vaja, Head of Sales

Tel: 0800 597 4462

Tel: 0800 597 4462

Michelle Sparrow, Business Development Manager

Tel: 01923 332 790

Email: dipesh@sigmaplc.com

Email: dipesh@sigmaplc.com

Pankaj Vyas - National Sales Manager

Head of Sales

Head of Sales

Email: michelle@sigmaplc.com

Tel: 07946 352 462

Rushin Mehta, Telesales Manager

Vithal Adatia - Account Executive

Email: pankaj@sigmaplc.com

Tel: 0800 597 4462, Option 3

Dipesh Vaja, Head of Sales

Telesales/Customer Service

Dipesh Vaja, Head of Sales

Sales Executives

Tel: 0800 597 4462

Tel: 0800 597 4462

Email: rushin@sigmaplc.com

Tel: 01923 331 407

Hitesh Haria, Telesales Supervisor

Email: vithal@sigmaplc.com

Tel: 0800 597 4462, Option 3

Email: hitesh@sigmaplc.com

Email: dipesh@sigmaplc.com

Email: dipesh@sigmaplc.com

Rushin Mehta, Telesales Manager

Rushin Mehta, Telesales Manager

Tel: 0800 597 4462, Option 3

Pankaj Vyas - National Sales Manager

Tel: 07946 352 462

Tel: 0800 597 4462, Option 3

Sharon Walker, Customer Services Manager

Email: rushin@sigmaplc.com

Tel: 0800 358 4427

Hinal Pandya, Specials Manager

Email: rushin@sigmaplc.com

Email: pankaj@sigmaplc.com

Tel: 0800 597 4475

Telesales/Customer Service

Email: cs@sigmaplc.com

Telesales/Customer Service

Email: specials@sigmaplc.com

Hitesh Haria, Telesales Supervisor

Hitesh Haria, Telesales Supervisor

Tel: 0800 597 4462, Option 3

Vithal Adatia - Account Executive

Tel: 0800 597 4462, Option 3

Email: hitesh@sigmaplc.com

Tel: 01923 331 407

Email: hitesh@sigmaplc.com

Email: vithal@sigmaplc.com

Sharon Walker, Customer Services Manager

Rushin Mehta, Telesales Manager

Tel: 0800 358 4427

Rushin Mehta, Telesales Manager

Sharon Walker, Customer Services Manager

Tel: 0800 358 4427

Tel: 0800 597 4462, Option 3

Business Development Team

Email: cs@sigmaplc.com

Tel: 0800 597 4462, Option 3

OTC Transfer Orders

Email: rushin@sigmaplc.com

Email: cs@sigmaplc.com

Email: rushin@sigmaplc.com

Hinal Pandya, Specials Manager

Tel: 0800 597 4475

Michelle Sparrow, Business Development Manager

Simone Elkerton OTC Transfer Orders

Tel: 01923 332 790

Business Development Team

Email: specials@sigmaplc.com

Hitesh Haria, Telesales Supervisor

Hitesh Haria, Telesales Supervisor

Tel: 0800 597 4462, Option 3

Tel: 0800 597 4462, Option 3

Email: hitesh@sigmaplc.com

Email: hitesh@sigmaplc.com

Lisa Farrant OTC Transfer Orders

Business Development

Tel: 01923 331 411

Email: michelle@sigmaplc.com

Sharon Walker, Customer Services Manager

Sharon Walker, Customer Services Manager

Tel: 01923 331 411

Email: sim@sigmaplc.com

Tel: 0800 358 4427

Tel: 0800 358 4427

Michelle Sparrow, Business Development Manager

Email: cs@sigmaplc.com

Email: cs@sigmaplc.com

OTC Transfer Orders

Michelle Sparrow, Business Development Manager

Tel: 01923 332 790

Sales Executives

Tel: 01923 332 790

Email: michelle@sigmaplc.com

Email: lisa@sigmaplc.com

Email: michelle@sigmaplc.com

Simone Elkerton OTC Transfer Orders

Business Development

Business Development

Tel: 01923 331 411

Pankaj Vyas - North London up to Midlands

Sales Executives

Tel: 07946 352 462

Lisa Farrant OTC Transfer Orders

Reshma Patel - North East & South London

Tel: 01923 331 411

Tel: 07767 163 171

Email: sim@sigmaplc.com

Sales Executives

Lizzie Harbidge Business Development Manager

Email: pankaj@sigmaplc.com

Lizzie Harbidge Business Development Manager

Tel: 07714 657 806

Tel: 07714 657 806

Pankaj Vyas - North London up to Midlands

Email: lisa@sigmaplc.com

Email: reshma@sigmaplc.com

Email: lizzie.h@sigmaplc.com

Email: lizzie.h@sigmaplc.com

Tel: 07946 352 462

Pankaj Vyas - National Sales Manager

Tel: 07946 352 462

Email: pankaj@sigmaplc.com

Email: pankaj@sigmaplc.com

Sales Executives

Sales Executives

Hinal Pandya, Specials Manager

Reshma Patel - North East & South London

Vithal Adatia - Account Executive

Tel: 07767 163 171

Tel: 0800 597 4475

Business Development

Tel: 01923 331 407

Email: reshma@sigmaplc.com

Email: vithal@sigmaplc.com

Email: specials@sigmaplc.com

Pankaj Vyas - National Sales Manager

Pankaj Vyas - National Sales Manager

Tel: 01923 444 999

Tel: 07946 352 462

Tel: 07946 352 462

Specials OTC Transfer Orders

Hinal Pandya, Specials Manager

Email: bd@sigmaplc.com

Specials

Specials

Hinal Pandya, Specials Manager

Email: pankaj@sigmaplc.com

Tel: 0800 597 4475

Email: pankaj@sigmaplc.com

Tel: 0800 597 4475

Email: specials@sigmaplc.com

Email: specials@sigmaplc.com

Simone Elkerton OTC Transfer Orders

Tel: 01923 331 411

OTC Transfer Orders

Email: sim@sigmaplc.com

Hinal Pandya, Specials Manager

Hinal Pandya, Specials Manager

Tel: 0800 597 4475

Tel: 0800 597 4475

Simone Elkerton OTC Transfer Orders

Vithal Adatia - Account Executive

Vithal Adatia - Account Executive

Tel: 01923 331 407

Tel: 01923 331 407

Email: vithal@sigmaplc.com

Email: vithal@sigmaplc.com

Lisa Farrant OTC Transfer Orders

Tel: 01923 331 411

Email: lisa@sigmaplc.com

Lisa Farrant OTC Transfer Orders

Email: specials@sigmaplc.com

Simone Elkerton OTC Transfer Orders

Email: specials@sigmaplc.com

Tel: 01923 331 411

Tel: 01923 331 411

Email: sim@sigmaplc.com

Email: sim@sigmaplc.com

OTC Transfer Orders

OTC Transfer Orders

Lisa Farrant OTC Transfer Orders

Tel: 01923 331 411

Email: lisa@sigmaplc.com

Tel: 01923 331 411

Email: lisa@sigmaplc.com

Simone Elkerton OTC Transfer Orders

Simone Elkerton OTC Transfer Orders

Tel: 01923 331 411

Tel: 01923 331 411

Email: sim@sigmaplc.com

Email: sim@sigmaplc.com

Lisa Farrant OTC Transfer Orders

Lisa Farrant OTC Transfer Orders

Tel: 01923 331 411

Tel: 01923 331 411

Email: lisa@sigmaplc.com

Email: lisa@sigmaplc.com

Meet the family of dis comfort

From the itch of pruritus ani to the pain of fissures, the UK’s #1 choice for haemorrhoid relief goes further to relieve a full range of anorectal conditions.1,2

Anal FissuresHaemorrhoidsProctitis Prur itus Ani

For every itch, pain, and irritation in the family — AnuSol brings trusted relief.1,2

• Clinically shown to provide fast, effective relief3

• Targeted support for haemorrhoids, pruritus ani, 1,2

• Soothes and reduces for immediate comfort4

The intolerable relatives

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Reduces haemorrhoid swelling and discomfort, helping patients 1,2,5-7

Pruritus Ani

Targeted relief for intense itching, protecting the skin and restoring comfort.1,2,7

Anal Fissures

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Proctitis

manage proctitis symptoms and enhance quality of life.1,2,10

Help your the comfort they need with one trusted recommendation:

Gentle relief, even during pregnancy

AnuSol Natural’s non-medicated formula with organic aloe vera, witch hazel, and calendula provides soothing comfort for pregnant and breastfeeding women.

Offer natural, effective relief from anorectal discomfort that mums-to-be can trust.11,12

AnuSol Cream (GSL) contains zinc oxide, bismuth oxide and balsam Peru. For the symptomatic relief of uncomplicated internal and external haemorrhoids, pruritus ani, proctitis and reactions, precautions, contra-indications, and method of use can be found at: https://www.medicines.org.uk/emc/ product/1486/smpc AnuSol Ointment (GSL) contains zinc oxide, bismuth subgallate, balsam Peru and bismuth oxide. For the symptomatic relief of uncomplicated internal and external about this product, including adverse reactions, precautions contra-indications, and method of use can be found at:

https://ww w. medicines .or g.uk/emc/p r oduct/1487/smp c AnuSol Suppositories (GSL) contains zinc oxide bismuth subgallate, balsam Peru and bismuth oxide. For the relief of internal haemorrhoids and other related ano-rectal conditions. Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at: https://www.medicines.org.uk/emc/ product/1488/smpc AnuSol Soothing Relief Ointment (GSL) contains zinc oxide, benzyl benzoate bismuth oxide, bismuth subgallate, balsam Peru and hydrocortisone acetate. For the symptomatic treatment of uncomplicated internal and external haemorrhoids and pruritus ani. Information about

this product, including adverse reactions, precautions, contraindications, and method of use can be found at: https://www. medicines.org.uk/emc/product/5389/smpc AnuSol Soothing Relief Suppositories (GSL) contains zinc oxide, benzyl benzoate, bismuth oxide, bismuth subgallate, balsam Peru and hydrocortisone acetate For the symptomatic treatment of internal haemorrhoids and pruritus ani. Information about this product, including adverse reactions, precautions, contraindications, and method of use can be found at: https://www. medicines.org.uk/emc/product/5406/smpc Church & Dwight UK Ltd., Premier House, Shearway Business Park, Pent Road, Folkestone, Kent, CT19 4RJ.

References: 1. Anusol Cream SPC. Available at: https://www.medicines.org.uk/emc/product/1486/smpc. Accessed: November 2024. 2. Anusol Ointment SPC. Available at: https://www.medicines. org.uk/emc/product/1487/smpc. Accessed: November 2024. 3. 4. Bacalbasa N, et al. Ro J Med Pract. 2022;17(Suppl3):8-11 5. Lohsiriwat V. World J Gastroenterol. 2012; 18(17): 2009-2017. 6. Bacalbasa N, et al. Ro J Med Pract. 2022;17(Suppl3):8-11. 7. Gupta M, et al. Dermatology Research and Practice. 2014;2014:709152. 8. Siddiqi S, et al. Ann R Coll Surg Engl. 2008;90(6):457-63. 9. Salati SA. Pol Przegl Chir. 2021;93:1-10. 10. Caron B, et al. Journal of Crohn’s and Colitis. 2022;16:922–930. 11. 12. Data on

Adverse events should be reported. Reporting forms and information can be found at https://yellowcard.mhra.gov.uk/. Adverse events should also be reported to Church & Dwight +44(0) 808 175 6410

The UK’s #1 BV Treatment*

How Balance Activ® BV Treatment Gel and Pessaries works:

Not a drug: Mimics the vagina’s own defence mechanism to treat and relieve BV, naturally.

Reliable: Clinically proven to work, for a dependable natural alternative.

Effective: Replenishes the body’s natural lactic acid to restore the vagina’s normal pH, rapidly relieving symptoms.

Balance: Tops up glycogen to encourage good bacteria and maintain pH balance to keep BV at bay.

Convenient: Comes with 7 single-use, gel-filled tubes –a week’s treatment – for easy and hygienic application.

The naturally working treatment for Bacterial Vaginosis: Available in 2 easy to use formatspessary & gel for added convenience.

Balance Activ Thrush Cream is not a drug, but a treatment with 3 benefits designed to help the body fight the cause, relieve the symptoms, and prevent the recurrence of thrush.

How Balance Activ® Thrush Cream works:

Not a drug: 3 benefits in 1 treatment to help the body fight the cause, treat the symptoms, and prevent thrush.

Protects: Restricts the growth of harmful bacteria, allowing the body to fight the cause.

Relieves: Provides relief from intimate itching, redness, and soreness.

Prevents: Retores and maintains a balanced vaginal pH and flora to prevent thrush from recurring.

Simple: No fragrance and paraben added.

Convenient: Includes 5 single-use applicators for easy insertion. Can also be used externally.

Thrush Cream

Bio-Oil ® Skincare Oil (Natural) 125ml P Spec altst ,c-.ar and

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Bio-Oil ® Dry Skin Gel 100ml e

Bio-Oil ® Body Lotion 175ml C

Speclallst body moisturiser Shako bclloro use,_ Applytwlco

• Relieves Excess Wind

Stomach Bloating • Cramping & Pain in the Digestive system

Anaesthetic Sore Throat Spray

0.71% w/v oromucosal spray benzocaine NUMBS IN SECONDS

of temporary breathing difficulty, face or mouth swelling. Methaemoglobinaemia has been reported with benzocaine use. Legal category: GSL MA Number: PL 18259/0001 (Menthol), PL 18259/0002 (Cherry), PL 18259/0005 (Honey & Lemon), PL 18259/0006 (Blackcurrant), PL 18259/0006 (Children’s Blackcurrant). MA Holder: Prestige Brands (UK) Ltd 5-7 London Road St. Albans AL1 1LA. Cost: Retail price (excluding VAT) £5.13 Date of preparation: July 2025.

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard. Adverse events should also be reported to Prestige Brands (UK) Ltd. *52 w/e 8th Feb 2025, unit sales. Total coverage – source Nielsen. To verify email: customerservicesdepartment@ceutahealthcare.com

Chloralieve Honey & Lemon Flavour 2mg/0.6mg/1.2mg lozenges. Chloralieve Blackcurrant Flavour 2mg/0.6mg/1.2mg lozenges. (lidocaine hydrochloride, amylmetacresol, 2,4-dichlorobenzyl alcohol). Indications: Relief of symptoms of sore throats in adults and adolescents over 12 years of ages. Posology and method of administration: 1 lozenge every 2-3 hours, up to a maximum of 8 lozenges in a 24-hour period for adults, and up to a maximum of 4 lozenges for children over 12 years of age. Slowly dissolve the lozenge in the mouth, do not dissolve in the sac of the cheek. Do not take this medicine before meals or drinking. Contra-indications: Do not use Chloralieve Lozenges in children under 12 years of age. Hypersensitivity to the active substances or to any of the excipients listed in section 6.1. A history of allergy to local anaesthetics of the amide type. In patients who have a history of or are suspected to have methaemoglobinaemia. Special warnings and precautions: If symptoms persist for longer than 2 days, worsen, or other symptoms appear, the patient should contact a doctor or pharmacist and the condition should be evaluated for bacterial infections. Do not use for more than 5 days. Follow the indicated dosage. Should not be used if greater acute wounds are present in the mouth or throat. Acutely ill and frail elderly patients are more susceptible to adverse effects. Risk of choking, altered sensitivity of the mouth and throat, pulmonary aspiration. Excipient warnings: Contains glucose and sucrose. Colourants may cause allergic reactions. Side effects: Rare: Hypersensitivity reactions, angioedema, urticaria, bronchospasm, hypotension, stinging of the throat and unpleasant taste. Not known: Pharyngeal edema, nausea, oral discomfort, swelling of the mouth, dysgeusia, rash. Legal category: P MA Number: PL 18259/0001 (Blackcurrant), PL18259/0012 (Honey & Lemon). MA Holder: Prestige Brands (UK) Ltd 5-7 London Road St. Albans AL1 1LA.

Cost: Retail price (excluding VAT) £4.79 Date of preparation: July 2025. Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard. Adverse events should also be reported to Prestige Brands (UK) Ltd.

UPTO 24.5%

New Cuticura Maize Body Powders

New Cuticura Maize Body Powders

Maize Body Powders

 Cuticura Body Powders: NEW Maize formulation.

 Available in 250g and 150g sizes.

 Cuticura Body Powders: NEW Maize formulation.

 New, easy to hold/handle plastic bottle and shaker.

 Available in 250g and 150g sizes.

NEW IMMEDIATE RESULTS FOP CLAIMS:

 Cuticura Body Powders: NEW Maize formulation.

 New, easy to hold/handle plastic bottle and shaker.

NEW IMMEDIATE RESULTS FOP CLAIMS:

 Tested with consumers for proven, instant results

 Available in 250g and 150g sizes.

 Tested with consumers for proven, instant results

 “Instantly absorbs, softens and protects for immediate comfort and relief.

 “Instantly absorbs, softens and protects for immediate comfort and relief.

 New, easy to hold/handle plastic bottle and shaker.

STRONGER PERFORMANCE CLAIMS:

STRONGER PERFORMANCE CLAIMS:

NEW IMMEDIATE RESULTS FOP CLAIMS:

 Consumer trials on new formulation have given us stronger claims:

 Tested with consumers for proven, instant results.

 Consumer trials on new formulation have given us stronger claims:

 BOP Claims now:

 BOP Claims now:  85% felt their skin felt smoother after one use  94% saw reduced chafing after 2 weeks

 85% felt their skin felt smoother after one use

 “Instantly absorbs, softens and protects for immediate comfort and relief.

 94% saw reduced chafing after 2 weeks

 OTHER claims:

 OTHER claims:

STRONGER PERFORMANCE CLAIMS:

 89% of consumers trialled claimed instant results from chafing.

 89% of consumers trialled claimed instant results from chafing.

 86% of consumers said powder cleared sweat and reduced irritation

 86% of consumers said powder cleared sweat and reduced irritation

 Consumer trials on new formulation have given us stronger claims:

 85% said skin felt instantly smoother.

 BOP Claims now:

 85% said skin felt instantly smoother.

New Cuticura Maize

 85% felt their skin felt smoother after one use

 94% saw reduced chafing after 2 weeks

 OTHER claims:

 89% of consumers trialled claimed instant results from chafing.

 85% said skin felt instantly smoother.

 Tested with consumers

“Instantly absorbs, comfort and relief.

 86% of consumers said powder cleared sweat and reduced irritation

STRONGER PERFORMANCE  Consumer trials claims:  BOP Claims now:

85% felt

94% saw

OTHER claims:

89% of consumers chafing.

 86% of consumers irritation

 85% said skin

Fast-acting, long-lasting relief

Difflam™ Sore Throat Rinse (benzydamine hydrochloride 0.15% w/v) & Difflam™ Oral Rinse (benzydamine hydrochloride 0.15% w/v). Indications: Locally acting analgesic and anti-inflammatory treatment for the relief of inflammatory conditions of the throat including pharyngitis. Legal category: P. Information about this product, including adverse reactions, precautions, contraindications and method of be found at: https://www.medicines.org.uk/emc/product/9258/smpc & https://https://mhraproducts4853. blob.core.windows.net/docs/c3ac96e2bbc807f0659dd78dade71a3cb4f368cd

Difflam™ 3 mg Lozenges (benzydamine hydrochloride) Lemon and Orange-Honey. Indications: Difflam™ lozenges is used and children above 6 years of age for symptomatic local treatment for the relief of pain and irritation of the mouth and throat. Legal category: P. Information about this product, including adverse reactions, precautions, contraindications and method of use can be found at: https://mhraproducts4853.blob.core.windows.net/docs/ec8a7f89fdcdc398a6d74f1ba0ac8cd8b284ca01

Marketing Authorisation Holder: Cooper Consumer Health B.V. Verrijn Stuartweg 60, 1112AX Diemen – The Netherlands

Date of preparation: August 2025

Ref number: MAT-DIF-00090

NOTHING STRONGER WITHOUT PRESCRIPTION FOR SORE THROAT PAIN

SPRAY RINSE LOZENGES

30 ml (0.15% w/v Benzydamine Hydrochloride)

• Fast-acting, on-the-go format

• Gets straight to where it’s needed

• Sugar, lactose and gluten free

Suitable for adults, children and babies (from 4 kg)

200 ml & 300 ml (0.15% w/v Benzydamine Hydrochloride)

• Measuring cup for accurate dosing

• Mint flavour

• Sugar, lactose and gluten free

3 mg Benzydamine Hydrochloride Lozenges

• Convenient for use anytime, anywhere

• Available in two flavours: Lemon

Suitable for adults and children

Suitable for adults and children

Dioralyte® Natural (GSL) Dioralyte® Blackcurrant (GSL) Dioralyte® Citrus (GSL) Dioralyte® Natural Sachets (P) Dioralyte® Blackcurrant Sachets (P) Dioralyte® Citrus Sachets (P)

Abbreviated Product information

Powder for

disodium hydrogen citrate 0.53 g in each sachet. Indications: GSL: For the treatment of

and

associated with acute diarrhoea. P: Oral correction of fluid and electrolyte loss in infants, children and adults. Treatment of watery diarrhoea of various aetiologies including gastroenteritis in all age groups. MA holder: Phoenix Labs, Suite 12, Bunkilla Plaza, Bracetown Business Park, Clonee, Co. Meath, Ireland. Further information is available from: Phoenix Labs. Always read the label. Tel +3531 5742410, email: medical information@phoenixlabs.ie.

Legal category: Dioralyte Natural (GSL) D oralyte Blackcurrant (GSL)Dioralyte Citrus (GSL), D oralyte Natural Sachets (P), Dioralyte Blackcurrant Sachets (P), Dioralyte Citrus Sachets (P). Information about these products including adverse reactions, precautions, contraindications and method of use can be found at:

Dioralyte Natural (GSL) www.medicines.org.uk/emc/product/2774/smpcDioralyte Blackcurrant (GSL) www.medicines.org.uk emc/product/2775/smpc

Dioralyte Citrus (GSL) www.medicines.org.uk/emc/product/2770/smpc

Dioralyte Natural Sachets (P) www.medicines.org.uk/emc/product/2771/smpc

Dioralyte Blackcurrant Sachets (P) www.medicines.org.uk/emc/product/2773/smpc

Dioralyte Citrus Sachets (P) www.medicines.org.uk/emc/product/2772/smpc

Date of preparation: January 2024

Dioralyte® Relief Raspberry (GSL)

Dioralyte® Relief Blackcurrant (GSL)

Dioralyte® Relief Blackcurrant Sachets (P)

Abbreviated Product information

Presentation: Powder for reconstitution with water containing pre-cooked rice powder 6 g, sodium citrate 580 mg, sodium chloride 350 mg, potassium chloride 300 mg in each sachet. Indications: GSL: For the treatment of fluid and electrolyte loss associated with acute diarrhoea. P: Oral correction of fluid and electrolyte loss in infants aged 3 months upwards, children and adults. Treatment of watery diarrhoea of various aetiologies including gastroenteritis from 3 months upwards. Particularly recommended in the case of too loose or frequent stools where it enables

#1 Skin Treatment Brand*

Cracked and itchy skin are two of the most common symptoms associated with sensitive skin

E45 Itch Relief Gel & Coolmouse

Cools & Soothes itchy skin in under 60 seconds

Scientifically proven to provide effective relief for itchy skin caused by eczema, dermatitis and pruritus.

E45 Itch Relief

E45

Itch Relief Gel & Coolmouse

Cools & Soothes itchy skin in under 60 seconds

Cream

Scientifically proven to provide effective relief for itchy skin caused by eczema, dermatitis and pruritus.

E45 Itch Relief Cream. For pruritus, eczema, dermatitis, and scaling skin conditions. Always read the label.
E45 Itch Relief Cream. For pruritus, eczema, dermatitis, and scaling skin conditions. Always read the label.

ESSENTIAL INFORMATION:

PRODUCT INFORMATION: ellaOne® 30 mg film-coated tablet (ulipristal acetate). Refer to the SmPC for further information. INDICATION: Emergency contraception (EC) within 120 hours (5 days) of unprotected sexual intercourse or contraceptive failure. Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at: https:// mhraproducts4853. blob.core.windows.net/docs/b0731d06d3693ecfbd3c4d15547cba88d0f7de6c

MARKETING AUTHORISATION HOLDER: Laboratoire HRA Pharma, 200 avenue de Paris, 92320 Châtillon, France. MARKETED IN THE UK BY: HRA Pharma a Perrigo Company, One Embassy Gardens, Viaduct Gardens, Nine Elms, London SW11 7BW, United Kingdom LEGAL CATEGORY: P

Date of last revision of text: October 2023. Unique ID: UK/ELLA/1672

INDICATION: Hana 75 microgram film coated tablets contains desogestrel and is indicated for oral contraception in women of childbearing age to prevent pregnancy. Refer to SmPC for further product information. Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at: https://mhraproducts4853.blob.core. windows.net/docs/ f4e6d09fb70790e19085f23d5723fbe70eca96e8 MARKETING AUTHORISATION

HOLDER: Laboratoire HRA Pharma, 200 avenue de Paris, 92320 Chatillon, France. MARKETED IN THE UK BY: HRA Pharma a Perrigo Company, One Embassy Gardens, Viaduct Gardens, Nine Elms, London SW11 7BW, United Kingdom. LEGAL CATEGORY: P. Additional information and full Product Information is available on request from HRA-UK@cambreg.co.uk

Date of last revision of text: October 2023. Company Reference: UK/HANA/0582

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard. Adverse events should also be reported to HRA Pharma on 0800 917 9548 or email HRA-UK@cambreg.co.uk

Date of preparation: December 2023. Code: UK/ELLA/1699.

need Muscles Muscles Magnesium Magnesium

Magnesium is an important element that contributes to normal muscle function. It also helps maintain normal nerve and psychological functions and contributes to a normal energy yielding metabolism. Each daily serving of Floradix Magnesium liquid provides 250mg of magnesium in a pleasant tasting liquid form.

Recommended Daily Dose Take preferably before a meal. Adults and children from 12 years: 20ml once daily

Children 6 - 11 years: 10ml once daily Children 3 - 5 years: 5ml once daily

Each daily, 20ml serving provides 250mg (67% RDA) of magnesium in a pleasant tasting liquid form.

Magnesi um supports normal muscle function

Size: 250ml VeggieVegan

INSTANT DRY EYE RELIEF THAT LASTS

FAST AND EFFECTIVE AGAINST HEAD LICE

References 1. EMC, electronic medicines compendium. Lemsip Max Cold & Flu Lemon. Updated March 2025. Accessed June 2025. Available at https://www.medicines.org.uk/emc/product/5612/smpc 2. EMC, electronic medicines compendium. Lemsip Max Cold & Flu Capsules. Updated March 2025. Accessed June 2025. Available at https://www.medicines.org.uk/emc/product/5617/smpc.

LEMSIP MAX COLD & FLU LEMON: Each powder sachet contains Paracetamol 1000mg, Phenylephrine Hydrochloride 12.2mg.

Indications: For relief of the symptoms of colds and influenza, including the relief of aches and pains, sore throat, headache, nasal congestion and lowering of temperature. Legal Category: GSL. MA Holder: Reckitt Benckiser Healthcare (UK) Ltd, Hull, HU8 7DS. Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at: https://www.medicines.org.uk/emc/product/5612/smpc

LEMSIP MAX COLD & FLU CAPSULES: Each capsule contains Paracetamol 500mg, Caffeine 25mg, Phenylephrine Hydrochloride 6.1mg.

Indications: For the relief of symptoms associated with the common cold and influenza, including relief of aches and pains, sore throat, headache, fatigue and drowsiness, nasal congestion, and lowering of temperature. Legal Category: GSL. MA Holder: Reckitt Benckiser Healthcare (UK) Ltd, Hull, HU8 7DS. Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at: https://www.medicines.org.uk/emc/ product/5617/smpc

Produced 27.06.25.

NOTHING STRONGER FOR

Eye Relief for All Occasions

Irritation & Redness Relief Eye Drops 0.012% w/v Naphazoline Hydrochloride. Pharmacy Only. Treatment of redness and minor irritations of the eye. Murine Hayfever Relief 2% w/v Eye Drops (GSL). Active Ingredient: Sodium Cromoglicate 2% w/v. Indications: For the relief and treatment of the eye symptoms of hayfever. Always read the label. murine.co.uk

Innovation in Virus, Cold & Flu Protection

SCIENTIFICALLY PROVEN

UNIQUE THIXOTROPIC SPRAY

Cough & Cold in Adults?

Improve recovery with Nasal Irrigation

Natural Buffered Saline Irrigation

Drug & Preservative Free

Helps relieve nasal congestion, sinus pressure, and cold & allergy symptoms

Helps promote easy breathing and better sleep during cold season

Trusted by healthcare professionals worldwide

From age 12 and above

Unique on the market

Recommended to use with Nasal Decongestant to prevent Nasal Bleeding and Nasal Dryness

For Nasal Dryness

Dryness due to Nasal Decongestant

High Altitude

Air travel

CPAP

From the age 6 and above 1 spray in both nostrils every 4 hours

A bottle last for a month

GETTING YOU THERE ONE TRY AT A TIME.

*By combining NiQuitin Clear Patch and NiQuitin Minis Lozenges provides significant improvement in quit rate vs patch alone. To verify contact verify@perrigo.com

NiQuitin Clear 21 mg patches PL 02855/0237 GSL & NiQuitin Minis Mint 2mg Lozenges PL 02855/0328 GSL are used to relieve and/or prevent craving and nicotine withdrawal symptoms associated with nicotine dependence. Contains nicotine to aid nicotine withdrawal. Requires willpower. Always read the leaflet. MAH: Omega Pharma Ltd, Wrafton, Braunton, Devon, EX33 2DL, UK. Information about this product, including adverse reactions, precautions, contra-indications and method of use can be found at: https://mhraproducts4853.blob.core.windows.net/docs/f91bbc0fa449a4d253d88e66d31ec846b6ebf5fb. https://mhraproducts4853.blob.core.windows.net/docs/a2b169571b9c71e5e87745b08f054b757c50f6ef. Price is at the discretion of the retailer. MAT-6433

Nurofen Cold and Flu. Summary of Product Characteristics. Updated March 2025. Accessed July 2025. Available at: Nurofen Cold and Flu - Summary of Product Characteristics (SmPC) - (emc) | 5626

COLD & FLU: Each tablet contains Ibuprofen 200mg and Pseudoephedrine Hydrochloride 30mg.

Indications: For relief of symptoms of cold and flu with associated congestion, including aches and pains, headache, fever, sore throat, blocked nose and sinuses. Legal Category: P. MA Holder: Reckitt Benckiser Healthcare (UK) Ltd, Slough, SL1 4AQ. Information about this product, including adverse reactions, precautions, contraindications, and method of use, can be found at: http://www.medicines.org.uk/emc/product/5626/smpc. RT-M-q48KHm

1.
NUROFEN

Nytol One-A-Night 50mg Tablets (P) contains diphenhydramine hydrochloride. An aid to the relief of temporary sleep disturbance. MAH: Omega Pharma Limited, Wrafton, Braunton, Devon, EX33 2DL, UK. Information about the product including adverse reactions, precautions, contra-indications and method of use can be found at: https://mhraproducts4853.blob.core.windows.net/docs/fa3316290dcfe1c72ba262c95492b35c5f6f010f

Nytol Liquid Caramel Flavour 10mg/5ml oral solution (P) contains diphenhydramine hydrochloride. As a sleep aid: as a short-term mild hypnotic. MAH: Omega Pharma Limited, Wrafton, Braunton, Devon, EX33 2DL, UK. Information about the product including adverse reactions, precautions, contra-indications and method of use can be found at: https://mhraproducts4853.blob.core.windows.net/docs/5b7be4aa5b67baa90e3e4f89381f9b88ed07b085. MAT-7330

Olbas Olbas

Care should be taken when recommending medicines for use in pregnancy as medicines can cross the placenta and may affect the fetus.

Product Authorisation Holder: Dexcel® Pharma Ltd. 7 Sopwith Way, Drayton Fields, Daventry, Northamptonshire NN11 8PB, United Kingdom. Legal classification: GSL. Product name: Pyrocalm Control® 20mg Gastro-Resistant Tablets. Ingredients: 20 mg Omeprazole. Indications: For the short-term treatment of reflux symptoms (e.g. heartburn, acid regurgitation) in adults. Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at: www.medicines.org.uk/emc/ product/9154. Fertility, pregnancy and lactation: Pregnancy: results from three prospective epidemiological studies (more than 1000 exposed outcomes) indicate no adverse effects of omeprazole on pregnancy or on the health of the foetus/newborn child. Omeprazole can be used during pregnancy. Breastfeeding: Omeprazole is excreted in breast milk but is not likely to influence the child when therapeutic doses are used. Omeprazole can be used during breastfeeding. Fertility: Animal studies with the racemic mixture omeprazole, given by oral administration do not indicate effects with respect to fertility. 1NHS Digital, Practice level prescribing data 2018/19 2pubmed. ncbi.nlm.nih.gov/9692700/ 3www.statista.com/statistics/378445/prescription-cost-analysis-top-twenty-chemicals-by-items-in-england/

Neutralises 99% of excess stomach acid in 60 seconds

Rennie® Peppermint (Calcium Carbonate 680mg and Magnesium Carbonate 80mg). Indications: For relief of indigestion and heartburn. MA Holder: Bayer plc, 400 South Oak Way, Reading, RG2 6AD, UK (information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at https://www. medicines.org.uk/emc/product/13863/smpc). Legal Category: GSL. Date of Preparation: March 2023. ® Registered trademark of Bayer AG.

1 30 seconds of your time could mean a lifetime of comfort and confidence for HRT patients.

Provides immediate, targeted relief from vaginal atrophy. Lasts up to 3 days per single application. 2-4

Trusted by HCPs, loved by patients. 8

Replens MD is a medical device.

Pre-filled applicators, x12 and x6 35g tube and re-usable applicator

References: 1. NICE CKS. Managing women with menopause, perimenopause, or premature ovarian insufficiency. https://cks.nice.org.uk/topics/menopause/management/management-of-menopause-perimenopause-or-premature-ovarian-insufficiency/. Accessed Nove 24. 2. Nachtigall, LE. Comparative study: Replens vs local estrogen in menopausal women. Fertitity & Sterility. 1994;61 (1):178-180. 3. Bachmann, GA, et al. Long term non-hormonal treatment of vaginal dryness. Clin Pract Sexuality. 1992;8:3-8. 4. Gelfand, MM, et al. Treating vaginal dryness in breast cancer patients: results of applying a polycarbophil moisturising gel. J Women's Health. 1994;3:427-433. 5. NHS. About vaginal ostrogen. January 2023. Available at: https://www.nhs.uk/-medicines/hormone-replacement-therapy-hrt/vaginal-oestregen/about-vaginal-oestrogen Last accessed November 2024. 6. British Menopause Society. Consensus statement. Urogenital atrophy. 2023-2024. 7. GPrX Extract Replens claim 2023. 8. Data on file. CIG Research on Pharmacy Views Attitudes and Opinions. October 2024.

Snufflebabe

Snufflebabe offers a whole range of gentle effective ways to help clear all kinds of sniffles to

with a dual-action formula of Paracetamol and Codeine for effective pain relief.

Paracetamol 500mg

Relieves your pain symptoms

Solpadeine® MAX Tablets

Suitable for:

Migraines

Headaches

Backache

Rheumatic pain

Period pain

Dental pain

Strains & sprains

Sciatica

in line with posology and treatment duration of 3 days use. NOW AVAILABLE IN 24 TABLET PACK SIZE ONLY TO REPLACE 20CT AND 30CT TABLETS

Codeine 12.8mg

Blocks messages from pain receptors

Solpadeine Max Tablets, Paracetamol 500mg, Codeine Phosphate Hemihydrate 12.8mg (P) contain paracetamol and codeine phosphate hemihydrate. For the treatment of acute moderate pain which is not relieved by paracetamol or ibuprofen alone, including migraine, headache, dental pain, period pain, backache, arthritic & rheumatic pain, strains & sprains and sciatica. MAH: Omega Pharma Ltd, Wrafton, Braunton, Devon, EX33 2DL UK. Information about this product, including adverse reactions, precautions, contra-indications and method of use can be found at: https://mhraproducts4853.blob.core.windows.net/docs/a255c8b82e05611d81b8ecebc7a8b54753c0c306

MAT-6056

Introducing: Stérimar™ Sinusitis

Very Blocked Nose

References: 1. Strefen Direct Cherry and Mint Flavour 8.75mg Oromucosal Spray. Summary of Product Characteristics. August 2024. Accessed July 2025. Available at: https:// www.medicines.org.uk/emc/product/15868/smpc. 2. Strefen Honey and Lemon. Summary of Product Characteristics. Updated November 2023. Accessed July 2025. Available at: https://www.medicines.org.uk/emc/product/6514/smpc. 3. Strefen Eucalyptus and Manuka Honey. Summary of Product Characteristics. Updated July 2024. Accessed July 2025. Available at: https://www.medicines.org.uk/emc/product/15831/smpc. 4. Strefen Orange Flavour Sugar Free 8.75mg Lozenges. Summary of Product Characteristics. Updated January 2025. Accessed July 2025. Available at: https://www.medicines.org.uk/emc/product/100409/smpc. 5. Data on file, Reckitt. 6. Blagden M, et al. Int J Clin Pract. 2002; 58:95–100. 7. Shephard A et al. Abstract presented at the European Congress of Clinical Microbiology and Infectious Diseases, 27–30 April 2013, Berlin, Germany.

ESSENTIAL INFORMATION:

STREFEN DIRECT CHERRY AND MINT FLAVOUR 8.75MG OROMUCOSAL SPRAY: One actuation contains 2.92 mg of Flurbiprofen, three actuations equal to one dose contains 8.75mg, corresponding to 16.2 mg/ml Flurbiprofen. Indications: For the short term symptomatic relief of acute sore throat in adults. Legal Category: P. MA Holder: Reckitt Benckiser Healthcare (UK) Ltd, Slough, SL1 3UH. Information about this product, including adverse reactions, precautions, contraindications, and method of use can be found at: https://www.medicines.org.uk/emc/product/15868/smpc.

STREFEN HONEY AND LEMON & STREFEN EUCALYPTUS AND MANUKA HONEY

FLAVOUR 8.75MG LOZENGES & STREFEN ORANGE FLAVOUR SUGAR FREE 8.75MG

LOZENGES: Each lozenge contains flurbiprofen 8.75mg. Indications: For the short term symptomatic relief of sore throat in adults and children over the age of 12 years. Legal Category: P. MA Holder: Reckitt Benckiser Healthcare (UK) Ltd, Slough, SL1 3UH. Information about this product, including adverse reactions, precautions, contraindications, and method of use can be found at: https://www.medicines.org.uk/ emc/product/6514 and https://www.medicines.org.uk/emc/product/15831/smpc and https://www.medicines.org.uk/emc/product/100409/smpc.

SORE THROAT

References: 1. McNally D, et al. Int J Clin Pract. 2010;64:194–207 2. Wade AG, et al. BMC Fam Pract. 2011;12:6. 3. Matthews D, et al. Int J Gen Med. 2018; 11:451–456. 4. Oxford JS, et al. Antivir Chem Chemother. 2005;16:129-134. 5. Shephard A, et al. Antiviral Res. 2015;123:158-162. 6. Morokutti-Kurz M, et al. Int J Gen Med. 2017;10:53–60. 7. Weckmann G, et al. Int. J Clin Pract. 2017;71(10) 8. EMC, electronic medicines compendium. Strepsils Honey & Lemon. Updated April 2021. Accessed June 2025. Available at https://www.medicines.org.uk/emc/product/5606 9. EMC, electronic medicines compendium. Strepsils Extra Triple Action Blackcurrant Lozenges. Updated August 2021. Accessed June 2025. Available at https://www.medicines.org.uk/emc/product/5601 10. EMC, electronic medicines compendium. Strepsils Sore Throat and Cough. Updated May 2021. Accessed June 2025. Available at https://www.medicines.org.uk/emc/product/8142

STREPSILS EXTRA TRIPLE ACTION BLACKCURRANT LOZENGES: Each lozenge contains hexylresorcinol 2.4 mg. Indications: An antiseptic and local anaesthetic for the relief of sore throat and its associated pain. Legal Category: GSL. MA Holder: Reckitt Benckiser Healthcare (UK) Ltd, Slough, SL1 3UH. Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at: https://www.medicines.org.uk/emc/product/5601/smpc.

STREPSILS HONEY AND LEMON: Each lozenge contains amylmetacresol (0.6 mg) and 2,4-dichlorobenzyl alcohol (1.2 mg). Indications: For the symptomatic relief of mouth and throat infections. Legal Category: GSL. MA Holder: Reckitt Benckiser Healthcare (UK) Ltd, Slough, SL1 3UH. Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at: https://www.medicines.org.uk/emc/product/5606/smpc

STREPSILS SORE THROAT AND COUGH: Each lozenge contains 2,4-dichlorobenzyl alcohol (1.2mg), amylmetacresol (0.6mg) and levomenthol (8.0mg). Indications: for the symptomatic relief of mouth and throat infections, dry, irritating cough associated with the common cold and nasal congestion. Legal Category: GSL. MA Holder: Reckitt Benckiser Healthcare (UK) Ltd, Slo9ugh, SL1 3UH. Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at https://www.medicines.org.uk/emc/product/8142/smpc

Produced 19.06.25.

PRODUCTS NOW AVAILABLE

6 DAY EARLY PREGNANCY

High sensitivity Midstream pregnancy test which can detect hCG in the urine as early as 6 days prior to the expected period date.

BLOOD PRESSURE MONITOR

Simple user-friendly blood pressure monitor which can store blood pressure readings for two users. Also includes irregular heartbeat detection. Product includes batteries and one year warranty.

TWIN MIDSTREAM PREGNANCY

Rapid Midstream pregnancy test delivers results in 1-3 minutes which can detect hCG in the urine as early as 4 days prior to the expected period date.

DIABETES SCREENING

A rapid, convenient and cost-effective method for the indirect measurement of blood sugar levels to assist in the diagnosis and management of diabetes. Contains three test strips.

TWIN STRIP PREGNANCY

Can be carried out by collecting urine and ‘dipping’ the test in the sample, over 99% accurate.

HEALTH CHECK-UP

A rapid, ten parameter, low-cost solution to evaluate a number of conditions affecting kidney, liver and heart etc. Six dipstick tests included.

URINARY TRACT INFECTION TEST

Urinary tract infections (UTIs) are common infections which affect the urinary tract, including the bladder (cystitis) urethra (urethritis) or kidneys (kidney infection). Suresign urinary tract infection test strips can aid in the detection of elevated levels of Leukocytes or Nitrites in urine, indicating inflammation or potential bacterial infection in the patient. Contains three dipstick tests.

UP TO 12 HOURS DRYNESS

The UK’s No1 Bladder Weakness Brand*

DAY OR NIGHT

TENA discreet pads effectively lock in moisture to keep you dry for up to 12 hours offering your customers superior protection day or night.

Help your customers find the perfect product for their needs with the TENA Product Selector Tool. Scan and try out today!

Source: *Bladder Weakness RSV% by Brand and Sub-Brand - Neilsen data up to 08.06.2024.

DESIGNED FOR MEN

TENA Men offers superior protection against light leaks and dribble up to large urine leaks and surges. Available in different shapes, sizes and absorbency levels so you can find the best product for your customers needs.

Help your customers find the perfect product for their needs with the TENA Product Selector Tool. Scan and try out today!

Source: *Bladder Weakness RSV% by Brand and Sub-Brand - Neilsen data up to 08.06.2024. ** International Consultation on Incontinence (ICI), publication 2013, Abrams et al. Award: MVP Awards Bladder Weakness & Incontinence, Pharmacy Magazine

NEW & IMPROVED

The UK’s No1 Bladder Weakness Brand*

TENA SILHOUETTE UNDERWEAR

Feminine and discreet pant, for total protection and management of moderate to heavy bladder leaks. Made 30% thinner than previous TENA Silhouette, for comfort, style and maximum discretion, without compromise on protection.

Help your customers find the perfect product for their needs with the TENA Product Selector Tool. Scan and try out today!

Source: *Bladder Weakness RSV% by Brand and Sub-Brand - Neilsen data up to 08.06.2024. **International Consultation on Incontinence (ICI), publication 2013, Abrams et all. † Winner Bladder Weakness Category. Survey of 8,000 people by Kantar.

The UK’s No1 Bladder Weakness Brand*

TOTAL SECURITY AND CONFIDENCE

TENA Pants protect+ Super TENA Pants protect+ Night Plus

TENA Pants Protect+ is designed for both men and women experiencing moderate to very heavy bladder and/or bowel incontinence. With a highly absorbent core that quickly and effectively locks in liquid, TENA Pants provide your customers with total security.

Help your customers find the perfect product for their needs with the TENA Product Selector Tool. Scan and try out today!

Source: *BLADDER WEAKNESS RSV% by Brand and Sub-Brand - Nielsen data to 08.06.24. Awards: MVP Awards, Older People’s Health, Pharmacy Magazine. PPOTY Awards Bladder Weakness Category, Independent Community Pharmacist.

UPTO 18.5%

NEW VALUAPK LAUNCHES

Nurture your Natural Balance with ValuOva

NOW AVAILABLE IN POTS

•EENHANCES IMMUNE F FUNCTION

•SSUPPORTS HEART

A AND B BRAIN HEALTH

•IIMPROVES MOOD AND C COGNITIVE FUNCTION

•SSTRENGTHENS

B BONES A AND JOINTS

•RREDUCES SYSTEMIC I INFLAMMATION

Voca l zone Th roat Pas t illes a re specifically fo r mulated to soothe vocal d iscomfort and throat irrita ti on f rom excess i ve si ng i ng, speak i ng or smoking . Fast and effective relief. Vegan, gluten

Sigma have served independent community pharmacy for the last 43 years. We will continue to serve you and assist you with your patient

H D Dental Ltd

23 Station Parade, Cockfosters Road, Barnet, Hertfordshire EN4 0DW

T: 020 8440 8442

E: info@cockfostersdental.co.uk W: www.cockfostersdental.co.uk

Riverside Pharmacy 135 High St, Town Centre, Rickmansworth WD3 1AR

T: 01923 772017

E: info@riverside-pharmacy.co. uk

W: www.riverside-pharmacy.co.uk

TRANSFER ORDER PRICE TRANSPARENCY

Sigma invoices will show both manufacturer and Sigma discounts per line.

SINGLES & OUTERS

For day to day buying, all products are available with a standard Sigma discount, irrespective of ordering a single or an outer.

MONTHLY PROMOTION BOOK

Includes a retail category management information booklet & lots of product information.

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