Molecular Genetics MPN MLPA Screening Panel Test Code: Test indication: Methodology: TAT: Sample type : Sample storage and Transportation: Recommendation: Sample unacceptable criteria: Genes Tested:
MPN MLPA JAK2 EXON 14 EXON 12 CALR and MPL Suspected myeloproliferative neoplasms. Detects JAK 2 (Exon 14 and 12), CALR and MPL mutations in peripheral blood or bone marrow. MLPA 3 working days 5 ml EDTA Whole Blood or EDTA Bone Marrow Sample to be stored and transported in 2 to 8 degree temperature Kindly include relavent clinical histroy and indications Sample collected in other than EDTA, samples not maintained in above recommeded temperature conditions, Clotted or hemolyzed specimen. JAK2, MPL and CALR
The current WHO diagnostic criteria for classic MPNs include presence of JAK2, CALR or MPL mutations
Other assays Available: Real time PCR based EGFR mutation detection (Liquid Biopsy is also performed in Plasma) BCRABL (Major), KRAS, BRAF, JAK2 (Exon 14). NGS based Cancer Hotspot assay covering almost all cancer types (Hotspots – Most frequent mutations)
94963 98078 85906 01094
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