Irish PharmaChem 2011

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MINISTER’S FOREWORD Richard Bruton TD, Minister for Jobs, Enterprise and Innovation, assesses the progress made by Ireland’s Life Sciences sector, and identifies priorities if the sector is to be a key component in our economic recovery. . . . . . . . . . . . 3 SECTOR OVERVIEW Matt Moran, Director of PharmaChemical Ireland, argues that Ireland’s pharma and biopharma sectors are ready and willing to meet the challenges ahead and can look to the future with confidence . . . . . . . . . . . . . . . . . 5 SUPPLY CHAIN The adoption of GS1 standards-based product and asset identification systems, coupled with EDI, greatly enhances the ability of all parties to secure the chain of custody throughout the healthcare supply chain. . . . . . . . . . . . . . . . . . . . 9 HEALTHCARE BIOTECHNOLOGY The Irish BioIndustry Association (IBIA) is working hard to put Ireland centre stage in the fight against disease, writes Michael Gillen, Director, Irish BioIndustry Association . . . . . . . . ..10 COVER STORY Utilising the expertise of Corkbased company CPI Technology can improve your centrifuge yield by up to 100%! . . . . . . . . . . . . . . . . . . . . 14 SOLVENTS Established in 1994, Soltec (Ireland) Ltd operates the only commercial solvent distillation facility in Ireland. . . . . . . . 17

MATERIALS HANDLING Irish Lift Trucks has announced a host of new developments to its range of Hyster forklifts and warehouse equipment. . . . . . . . . . . . . . . . . . . 30 SCIENCE FOUNDATION IRELAND Science Foundation Ireland is investing in research teams to generate new knowledge, leading edge technologies and competitive enterprises in the fields of science and engineering. . . . . . . . 18 LABORATORIES Lancaster Laboratories’ innovative, award-winning, in-sourcing solution helps GMP laboratories to address the upcoming EU Directive. . . . . . . . . . 20 RECRUITMENT 2011 looks to be brighter for recruitment in the pharmaceutical and Life Science sector, according to the results of a new study by Berkley Group. . . . . . . . . . . 23 PHARMACEUTICAL PACKAGING Pascal Keogh, MD of Millmount Healthcare, explains how utilising CMOs and CPOs as part of a long-term strategy can help pharmaceutical manufacturers to adapt to the demands of the modern pharmaceutical industry, while cutting costs. . . . . . . . . . . . . . . . . . . 25 RESEARCH & DEVELOPMENT PharmaChemical Ireland has identified five key research areas, which will provide opportunities for the industry to make Ireland a global pharma centre of excellence. . . . . . . . . . . . 28

published by: Tara Publishing Co. Ltd. 1/2 Poolbeg Street, Dublin 2. Tel: 241 3095 Fax: 241 3010 Email: kathleenbelton@tarapublishingco.com Managing Director: Fergus Farrell Director: Kathleen Belton Editorial: John Walshe Advertising Executive: Adrian Murphy Design and Origination by: Rooney Media, 73 Block A Rockbrook, Sandyford, Dublin 18 Printed by: W&G Baird

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CHEMICAL DISTRIBUTION IRELAND Director Nessa Moyles explains the work of Chemical Distribution Ireland in the realm of industry best practice and responsible care. . . . . . . . . . . . . 33 LIVE EVENTS Paul Smith, Irish Sales Manager, Clip Exhibition and Display, explains how his company can take the stress out of organising live events. . . . . . . . . . . . 34 CONTAINMENT TECHNOLOGY ProSys is on course to become the preferred supplier of Custom Containment Equipment to the pharmaceutical production industry worldwide. . . . . . . . . . . . 37 PACKAGING Contego Packaging supplies the pharmaceutical industry with cartons, leaflets, labels and blister pack foils from 10 sites across Europe, including their plant in Waterford . . . . . . . . . . . . . . . . . . . . . . . 39 PORTABLE COLD STORAGE Dawsonrentals Ireland offers high quality, flexible cold storage solutions, tailored to clients’ individual needs. . . 41 Listings Chemical Suppliers. . . . . . . . . . General Suppliers . . . . . . . . . . . Company Listings . . . . . . . . . . . Useful References . . . . . . . . . . .

42 44 53 64

Irish Pharmachem 2011 gratefully acknowledges the assistance of PharmaChemical Ireland in the production of this publication. Every effort has been made to ensure the accuracy of the information contained in this publication, but the publisher cannot accept responsibility for errors or omissions.


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Minister’s Foreword

Future Proofing the Life Sciences Sector Richard Bruton TD, Minister for Jobs, Enterprise and Innovation, assesses the progress made by Ireland’s Life Sciences sector, and identifies key priorities if the sector is to be a key component in our economic recovery.

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s Minister for Jobs, Enterprise and Innovation, I am very pleased to provide this foreword for the Irish PharmaChem Yearbook and Directory. The Life Sciences sector comprises of pharmaceuticals, medical devices and healthcare services. Certain aspects of the sector include specialist foods. We are fortunate, through many years of hard work and by having attractive enterprise policies and a skilled workforce, that we now boast some 45,000 high quality jobs across this sector, and some €44 billion in annual exports. Because of this work, I am pleased to say that: • Nine of the top 10 pharma and 15 of the top 25 medtech companies have operations in Ireland; • Six of the world’s top 10 drugs are made in Ireland; • We are the number one location in Europe for Life Sciences projects; • We are Europe’s largest device exporter per capita; • Investment in industry-related R&D in Ireland continues to rise.

achieved for Irish based companies in securing FP7 grant aid through enhanced collaboration. As the world becomes more competitive and globalised, we must develop new and better ways of working. We must create innovative products and services and access global markets to deliver them. In this context, the increasing competence and success of Irish Life Science research continues to break new ground in critical areas. Our research teams in molecular cell biology, human genetics, glycobiology, immunology and cancer are all making strides of global relevance. We are extending our strong fundamental research base and moving it increasingly towards a highly productive interface with Ireland’s large pharmaceutical and medical device sectors. A large number of research groups have also embraced new platforms for genomic and proteomics research. This is one of the future platforms, which will deliver for personalised medicine. Looking at the global market, we see continued growth but also real challenges in securing market access and reimbursement for products that are not truly differentiated and designed around patient need. Being close to patients, and understanding the needs of purchasers, has never been more important as healthcare costs globally continue to rise. More than ever, the outcome defines the worth of the investment.

A Partnership Approach In order to build on this success to date, a partnership approach is crucial. The scientific research community in our higher education institutions must work closely with their colleagues in industry for the greater good of the economy and Irish society. We have already seen good progress in this regard with the nurturing and development of industry-academic partnerships, supported by Government funding through Enterprise Ireland and Science Foundation Ireland. Additionally, we are seeking to energise greater collaboration between Irish research institutes and companies and partners in Europe. We want to see significant success

Clinical Research Facilities Our on-going investments through the Health Research Board into clinical research facilities and an expanded grouping of clinical networks will support the development of better-tailored therapies for patients. The passage of the Health Information Bill by the Oireachtas will address aspects of clinical trials and data 3


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around their core operations and expand into global hubs for their parent companies. The number of Irish sites that now operate as their main European hubs is testament to the success and importance of this strategy.

Facing

the

Challenge Ahead

Ireland faces daunting challenges from the present financial crisis. We have outlined our path to recovery and we are working with our European partners to rebuild our economy and our global reputation. We are now firmly fixed back on what made us successful: making products that the world wants. Our industry is exporting strongly and lower costs have greatly improved our competitiveness in global markets. We are conscious of the opportunities presented by enhanced collaboration between our industry sectors and state agencies. We want to see better co-operation and collaboration between ICT, medtech and pharmabio sectors, so that we can develop and supply the products and services of tomorrow.

protection, so that it becomes easier to develop new medicines and devices from Ireland. We are working with our regulators to ensure that Ireland provides a quality-based location from which to develop, launch and scale global products in healthcare. Through investments from my Department, made by IDA and Enterprise Ireland, we are working with industry to develop more efficient processes so that we can compete with lower cost locations. The biotech sector is redefining possibilities, with new vaccines for cancer, targeted therapies for inflammatory disease and better-tolerated agents in arthritis and orphan diseases. We know that global companies wish to preserve their product integrity and manufacturing excellence. Ireland’s declining cost base has greatly helped our competitive position at a time when global pharmaceutical companies are deciding on their future operations base. Ireland has come through these decisions very well to date. We can continue to be a global hub for small molecule manufacturing if we continuously innovate and manage costs, as other sectors are doing.

We have strong capabilities in areas as diverse as software and nanotechnology. Apple has proven that tapping into customer mindsets, and truly developing innovative products that serve unmet needs, can bring outstanding results. That is the work we are trying to support. Our continued support for the R&D budgets and the investments made through SFI and PRTLI confirm our commitment to the belief that we must think and export our way out of the present national difficulty. We remain committed to maintaining our corporation tax rate at 12.5%. We are determined that the business and regulatory environments will continue to be strongly pro-enterprise. We will continue to seek to strengthen our competitiveness, through addressing issues on costs, infrastructure, access to finance, and science, technology and innovation. We are determined to secure a bright future for industrial production in Ireland, to the benefit of all sectors, including, of course, pharmaceuticals and Life Sciences in general.

The Biotech Sector The biotech sector is performing well. With increasing R&D and some expansion within existing biopharma sites, Amgen’s acquisition of the Pfizer plant on Pottery Road for a large sterile fill and finish facility underlines our strong value proposition. Amgen is the world’s number one biotech company. In coming to Ireland, it joins other outstanding names such as Genzyme, Eli Lilly, Pfizer, Janssen Bio, Ipsen, Elanco and Merck. All of these companies are innovating and manufacturing for global markets, and exporting their products all over the world. In support of these activities, Ireland’s logistics and services innovation delivered new employment projects in Alere, Eli Lilly, and Merck in the past 12 months. These are major financial and resource operations for EMEA, and bolster our value proposition. We strongly endorse PharmaChemical Ireland and IDA’s challenge for companies to seek to develop services

Richard Bruton TD, Minister for Jobs, Enterprise and Innovation

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Sector Overview

PCI Points the Way to Pharma Success Matt Moran, Director of PharmaChemical Ireland, argues that Ireland’s pharma and biopharma sectors are ready and willing to meet the challenges ahead and can look to the future with confidence.

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• A fully-integrated development network for overall corporate structure; • Capacity and capability for clinical trials manufacture; • Regional HQ status for supply chain components, where it makes economic sense to concentrate them at one location; • A strong local management team; • A flexible workforce that can facilitate change on an ongoing basis. The industry has been working to ensure that each of these attributes is developed on all sites in this country. To date, progress has been good and as follow-up to the strategy launch in 2010, PCI will launch a follow-up report during BIO 2011 in Washington DC. This report demonstrates the progress a number of companies have made here. PCI intend to promote the report extensively in the USA, as well as in Europe. Given the difficult economic times Ireland finds itself in, it is important that the country effectively promotes those parts

ast year, March 16 to be precise, PharmaChemical Ireland (PCI) launched a major strategy document at the Drug Chemical and Allied Technologies (DCAT) meeting in New York City. The strategy, titled ‘Innovation and Excellence’, saw PharmaChemical Ireland set out a clear roadmap for the industry in Ireland, a roadmap designed to help the industry confront and overcome the many hurdles now placed before the sector, globally as well as locally. Since the launch, PCI has been working on execution of this strategy via its Standing Committee on Strategy, established around the time of the launch. PCI has received excellent support from Government, its respective agencies and the research community through their active participation in the work of this committee.

Follow-Up PCI identified the attributes which it believed the factory of the future should possess if it were to thrive and prosper in this new, much more challenging environment. To recap, these are summarised below: • Highly-efficient, cost-effective manufacturing with the full implementation of the principles of lean manufacturing and operational excellence; • Best practice in regulatory management, including principles of quality by design and process analytical technology; • On-site process and product development capabilities fully integrated into manufacturing; • Site of choice for transfer of all new entities to market; • Flexible and adaptable production facility; • On-site pilot plant facilities; • An on-site unit aimed at training the workforce in the latest principles of Lean, Six Sigma, etc; • Fully networked and research infrastructure; • Best practice in systems and information management; • Best in class in all aspects of environment and health and safety (EHS) management;

Matt Moran, Director, PharmaChemical Ireland.

5


Sector Overview

of the economy that are still prospering. With exports of over €50 billion in 2010 and employing over 24,000 directly, creating another 24,000 indirect jobs, the pharmachem sector is a prime example of this.

Solid State Pharmaceutical Cluster (SSPC) The Solid State Pharmaceutical Cluster (SSPC) offers complementary research activities to industry in areas such as chemical engineering, organic chemistry, physical property science, polymorphism, analytics and pharmaceutics. The SSPC is intended to provide the necessary skill set to comprehensively investigate pharmaceutical solids by bringing together complementary academic and industrial groupings from the disciplines of chemistry, pharmaceutics, pharmaceutical technology, chemical and mechanical engineering. These groups have expertise in process modelling and design, scale-up, computational fluid dynamics, on-site solution and solid-phase monitoring, crystallography and powder characterisation.

Cost Base Coupled with the above, Ireland is set to benefit from falling costs. The European Commission forecasts that Irish unit labour costs will fall by over 8% in the period 20082012. Relative to the EU average, this is an improvement of 14%. Irish energy costs have come down substantially. During 2008, the cost of electricity for large energy users was 37% more in Ireland than in the EU-27. By 2009, this gap had narrowed to 10% and by the first half of 2010 (latest data available), Irish electricity prices were 8% below the EU-27 average. The price of natural gas has moved from 15% above the EU-27 average in 2007 to 7% below by the first half of 2010 (see charts below).

The SSPC conducts industry-informed research, addressing three key areas for industrial partners:

Unit labour cost forecast % change 2008-2011

1. Providing industry-informed PhD’s to the sector in general; 2. Developing short term, company-specific mini projects; 3. Engaging multiple company/academia researchers in collaborative industry-wide research topics: - continuous crystallisation: determining the best future practice in this area; - particle engineering: addressing throughput issues around isolation and drying of API’s; - primary secondary interface: identifying the attributes of the API/excipient that influence the formulation process.

United Kingdom Italy EU-27 France Portugal Ireland

-10.0

-5.0

0.0

5.0

10.0 15.0

The SSPC is supported by companies such as Clarochem, Hovione, MSD, GSK, Eli Lilly, BMS, Janssen and Pfizer, who work closely with University of Limerick (centre base), TCD, UCC and NUIG. It has proved a very successful model and the industry is actively exploring ways of further developing and expanding its scope and work.

Source: European Commisson

Energy price differential (%) relative to EU-27 average 40 20 0 -20

Companies Deepening Roots 2007

2008

Electricity

2009

in Ireland

A number of companies are making significant progress towards becoming recognised centres of excellence in the supply, development and manufacturing of products. Just three samples of what has been achieved follow.

2010

Gas

Case Studies

Formulation R&D and Manufacturing Facility, MSD, Ballydine

The report contains a number of interesting case studies that clearly show how the industry is progressing here. The PCI strategy highlighted the importance of broadening the mandate of existing manufacturing facilities into process and product development. The Solid State Pharmacetical Cluster, established in 2008, is an excellent example of how the industry can work with the research community, with the support of Science Foundation Ireland (SFI), to achieve this.

In September 2007, construction started on a new formulation R&D manufacturing facility located on MSD’s existing Ballydine site. This €100m investment, backed by the IDA, will support MSD’s commercialisation initiative to bring new medicines to market more quickly and flexibly, and will significantly increase the overall level of R&D conducted at the site. 6


Sector Overview

ing technology, in addition to providing pilot scale batch processing capability. This additional capability has been a key factor in allowing the PDC to continue to deliver significant cost, productivity and environmental benefits to Pfizer through the application of innovative science and technology.

Eli Lilly, Kinsale, Co Cork In addition to recent investment in state-of-the art biopharmaceutical facilities in the last three years, Eli Lilly’s Kinsale site has been transformed into a key commercialisation partner for the Lilly Product Research and Development group. The site is now the first choice location for pre-validation scale-up activities for the emerging portfolio. This has been enabled by the provision of a suite of manufacturing facilities at 5, 50, 250 (in construction) and 2,000 gallon capacity, as well as parallel technology and capability in areas such as PAT, crystallisation, continuous processing, data-rich experimentation and advanced analytical diagnostics. Substantial collaboration with third-level institutions has been a significant factor in the progress of this initiative. Five projects have been completed to date, with several more currently in progress.

This worldwide centre for formulation R&D will develop innovative platforms for the formulation of solid dosage pharmaceutical products used in late stage clinical trials. The facility will also enable the plant to produce tablets/capsules for a number of new products in late stage clinical trials and manufacture launch quantities of newly approved products. Since 2007 a total of 50 new high-calibre roles have already been introduced as part of this development, which will become fully operational in 2011. The facility recently received its manufacturer’s license and its IMP (Investigational Medicinal Products) license from the Irish Medicines Board and is currently executing formulation development in support of two new candidate products in phase III clinical trials.

The Global Process Development Centre (PDC), Pfizer Ringaskiddy API Plant, Cork The Global Process Development Centre (PDC) was founded in 2001 to focus on developing innovative science and technology solutions to achieve operational and technical excellence in API synthesis. The PDC employs a wide range of skills across chemistry (synthesis/analytical), engineering and biocatalysis, which facilitate the development of new technology for Pfizer’s priority products to meet pre-defined environmental, cost and productivity targets. The PDC supports each step of the API process engineering project, from proof of concept through regulatory submission to commercial implementation. In addition, Pfizer recognised the need to have a flexible, state-of-the art modular kilo facility capable of supporting API process development. Hence, the Kilo Technology Laboratory (KTL) facility was launched in late 2008 to support the development of continuous process-

Conclusion There can be no doubt that the next few years will be very challenging for the pharmachem and biopharma sectors in Ireland. However, PCI does believe that the sector here is more than capable of meeting these challenges. There will be change in the sector, some of it painful, but the majority of it transformational. The examples above give a taste of what is happening in the sector here. Taken along with the recent announcement by Amgen to purchase the Pfizer Dun Laoghaire site, I believe all bodes well for the longterm future of the sector. PCI, along with the industry, is ready and willing to play its role in leading this country to prosperous times again. 7


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Healthcare Biotechnology

The Healthcare of the Future The Irish BioIndustry Association (IBIA) is working hard to put Ireland centre stage in the fight against disease, writes Michael Gillen, Director, Irish BioIndustry Association and Senior Executive, Pharmachemical Ireland.

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ealthcare biotechnolDid you know? ogy refers to a medicinal • More than 350m patients have already or diagnostic product or a benefited from approved medicines vaccine that consists of, or manufactured through biotechnology to has been produced by the use of, living treat or prevent cancers, heart attacks, organisms. It has a tremendous impact stroke, multiple sclerosis, leukemia, on meeting the needs of patients and diabetes, rare and other diseases. their families - it not only encompasses medicines and diagnostics that are manu• 650 new biotech medicines and vacfactured using a biotechnological process, cines are currently being developed for more than 100 diseases. but also gene and cell therapies and tissue engineered products. Today, the majority of innovative • In Europe, there are more than 60 approved orphan medicinal products, medicines, whether manufactured using most of them biotech medicines, for biotechnology or via a chemical synthesis the prevention or treatment of rare, like a traditional small molecule medicine, life-threatening or serious conditions. and many diagnostic products, are made Michael Gillen, Director, Irish available by applying modern biotechnolBioIndustry Association and Senior • Whilst the individual number of ogy in their development and/or manufacExecutive, PharmaChemical Ireland. patients suffering from rare diseases turing processes. might be low, all together, more than The Irish BioIndustry Association (IBIA), the representative voice of the biotechnol30m Europeans are affected. ogy sector in Ireland, working closely with colleagues in EuropaBio, are committed to developing new products that • With the completion of the human genome maphelp society live better, longer and healthier. By working ping and the resulting improved understanding of closely with the various stakeholders, the IBIA is cominter-individual variability, current medical science is mitted to the development and implementation of sound evolving towards a “personalised” approach, in which policies that will lead to innovative solutions to unmet we are better able to develop and subsequently target medical needs. medicines to patients who are more likely to benefit.

The Impact

of the

Financial Crisis

Over the last two years, the financial crisis has had a dramatic and negative impact on the healthcare biotechnology industry, not only by limiting access to finance for smaller companies, but also by pressing national governments into implementing measures to contain costs in their healthcare systems and on their science and research budgets. Often the first affected area by these cost containment measures is the spending on research into, and uptake of, innovative biotech medicines. Often short-term by nature, these measures, including narrow Health Technology Assessments (HTAs) and pricing and reimbursement processes, should ensure that patients benefit in the long-term from these healthcare innovations, while ensuring health systems get value for money. 10


Healthcare Biotechnology

• The pharmaceutical industry is increasingly shifting towards biotechnology. Projections estimate that in 2014, 50% of the top 100 drugs will be biotech medicines. • By 2015, the OECD estimates that healthcare biotechnological knowledge will be used in the development process for all new pharmaceuticals. • More than 70% of biotech and pharmaceutical companies in the EU-27 have less than 50 employees. Although small, biotech SMEs provide the high valueadded jobs that will help the EU achieve its goal of becoming the foremost knowledge-based economy in the world. • Recently, larger biopharmaceutical companies have tended to place greater reliance on outsourced R&D, mostly coming from emerging biotech SMEs. These programmes now represent as much as 30% to 50% of the pipeline for many major companies.

through constructive dialogue between stakeholders, a better mutual understanding of such concerns. Underpinning this responsibility are three principles that the IBIA believe is necessary to grow the industry base in Ireland and the wider European community.

• The total export value of the Irish pharma and biopharma industry in 2010 was in excess of €50 billion. That is over half of the GDP of the country.

1. Achieving Better Policy Making Through Science Science is a fast driver of innovation, providing patients with cutting-edge healthcare solutions to address unmet medical needs. The IBIA’s role is to foster open discussion and exchange between all relevant stakeholders in order to improve the understanding of the latest developments in science. Ultimately, we believe that a better understanding of science leads to the setting of better policies. Take for example, the issue of personalised medicine. With the completion of human genome mapping, it became clear that biology is much more complex than expected. Research into understanding inter-individual variability at several molecular levels has continued worldwide. Private and public scientific developments are strongly driving the medical paradigm towards an approach that ensures the right treatment to the right patient at the right time. This personalised medicine approach combines predictive diagnostic and therapeutic tools to create predictable outcomes and tailor medical treatment to the individual characteristics of each patient. This change is not only driven by scientific advances but also by society’s demand for novel solutions to old problems and more efficient therapies. Modern healthcare biotechnology methods and tools such as gene and cell therapies have the potential to answer this demand, providing personalised, innovative, safe and effective healthcare biotech products for patients. There are now a growing number of biomarkers, genetic and proteomic tests being developed and validated to identify patients who will most likely respond to associated treatments. Applications of personalised medicine go beyond therapeutic usage and are also increasingly used in drug development, from pre-clinical to clinical development. A variety of tools help identify respondents, non-respondents and

Innovative Medicine The European Commission (EC) has launched its strategy to achieve a more competitive and socially inclusive European Union by 2020, as well as the first European Innovation Partnership in the field of active and healthy ageing. Furthermore, Commission Vice-President Antonio Tajani is leading a new initiative to improve access to innovative medicine in the European Union (EU) – the socalled ‘Process on Corporate Responsibility in the Field of Pharmaceuticals’. Nevertheless, there is growing concern among the healthcare biotech industry that an irreversible disconnect is emerging between the long-term access policies promoted at EU level and the short-term actions taken at EU Member States level. Healthcare biotechnology provides patients with new and targeted solutions for a wide range of major diseases, such as cancer, diabetes or stroke. However, while healthcare biotechnology can support governments in their efforts to enhance the sustainability of their healthcare systems, cost containment measures can also have the contradictory effect of hampering innovation and access for patients by delaying or limiting entry into market of new technologies. The biotechnology industry in Ireland is committed to the socially responsible use of biotechnology to improve the quality of lives, to treat and cure diseases. Indeed at a wider European level, this commitment extends to improve the quality and quantity of food, to produce chemicals and to sanitise and to prevent release of hazardous wastes. The biotechnology industry recognises its responsibility to address societal ethical concerns and to encourage, 11


Healthcare Biotechnology

The healthcare biotechnology industry is a critical source of innovation and, as such, is a key player within the EC reflection ‘Vision for European Union in 2020’. Today, the sector is seven times larger than it was 10 years ago and has a 20% annual growth rate. However, due to the complexity of the sector (i.e. products, policies and regulatory environment), healthcare biotech’s contribution to society is at best underestimated. The value of an innovation tends to be split into at least two categories: breakthrough innovation and incremental innovation. Breakthrough innovation can either be established by a landmark discontinuity or be the result of discrete incremental improvements. Such minor increments may ultimately be just as important to patients. An example from within the healthcare biotech area could be an improved mode of administration of a medicine rather than a new medicine, as such. Failing to also acknowledge and reward all categories of innovation, including incremental innovation, will undermine a vital part of the innovation process. patients who are likely to suffer from adverse reactions. As a result, pre-clinical and clinical trials are likely to become smaller, safer, more focused, faster and less expensive. From a public health perspective, tailoring treatments to patients who are most likely to derive benefits from them will contribute to a re-distribution of financial resources in healthcare systems in a more rational way. The personalised medicine approach has the potential to bring more effective and safer treatments to the market, as well as reducing the use of ineffective treatments and the number of adverse reactions – thereby reducing unnecessary hospitalisations. 2. Achieving Regulations that Support Innovation A sound regulatory framework encourages and stimulates responsible innovation to help people live longer and healthier lives. The IBIA brings its expertise and experience into all key regulatory discussions to help in the development of a predictable and workable framework. Our involvement in, and commitment to, such an approach will ultimately improve the timely access to new medicines. Furthermore, it will improve the competitiveness and attractiveness to investors of the healthcare biotech sector in Ireland. At a European level this involves working closely with our colleagues in EuropaBio to ensure that we maintain an innovative and viable European bioscience industry that can compete globally.

Our role in the IBIA is two-fold: i) To promote the medical, economic and societal benefits of biotech innovation; ii) To engage with all relevant stakeholders in constructive interactions to explore ways to maintain and to strengthen the industry’s innovative efforts.

3. Achieving better access to market throughout the EU Regardless of their country of residence, all patients deserve timely access to innovative therapies. However, as EU Member States increasingly resort to cost-rationing measures to contain their healthcare expenses, promoting the value and uniqueness of biotech medicines has become essential to ensure that tools such as HTA or tenders are used appropriately and do not reduce patients’ access to life-saving therapies.

We will continue to work to adopt a holistic approach to policy-making and implementation at a national and European level and in turn ensure effective and innovative European healthcare systems for patients’ benefit. This article is adapted from the EuropaBio healthcare manifesto 2011.

12


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from caps to bottles... Whether it needs dispensing, dropping or plugging, Measom Freer has an extensive stock range of plastic dropper caps, nozzles, spouts and plugs to complement our bottle and packaging ranges. You could find that we have the perfect solution for dispensing your solution right here, ready for dispensing. Whatever you need, we’ve been providing a personal service with great attention to detail for 70 years – so you can rely on Measom Freer to provide the ideal plastic packaging solution. For an illustrated catalogue, or to request samples, contact our sales department.

Tel: +44 (0) 116 288 1588

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Cover Story

Improve Your Centrifuge Yield with Utilising the expertise of Cork-based company CPI Technology can improve your centrifuge yield by up to 100%!

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ased in Cork, CPI try today. It is true to say that Technology are a centrifuge technology separates leading provider solids from liquids with a higher of advanced procefficiency than all other solid ess equipment and specialty liquid separation technologies, services to the pharmaceutical, such as filter presses, filter succhemical, biotechnology, food tion strainers (nutsche filter and beverage and energy gendryers), belt filters or thermal eration sectors in the Irish, UK drying. Indeed, mechanical and European markets. separation is approximately In collaboration with 10 times less expensive than their world class partners, CPI thermal drying of a similar type Technology offers unrivalled product. expertise and experience in the Centrifuge technologies provision of new capital procdeliver the highest yield and ess equipment, coupled with the the driest product with the most optimisation and on-site servicing efficient wash effect and within of existing process equipment and the shortest possible time. But this plant, including reactor technology assumes the equipment is operatand agitation, vacuum pumps and ing at its peak level. systems, pumps and fluid handling Process optimisation of a cenDeliver absolute results direct to the bottom equipment, chemical dosing systems, trifuge begins with identifying the line profit with centrifuge optimisation. glass lined technology, high conoptimum process conditions specific tainment isolators, tank protection to individual products for a given equipment and the subject of this article – solids liquids machine type, together with the testing and implementation separation/dryer technology. of those conditions, to deliver absolute results direct to the Liquid/Solids separation is recognised by many in the bottom line profit. industry as being the most important part of the pharmaceutical and fine chemical process, and centrifuge technolHow to Implement a Three-Step Centrifuge Plan ogy has long been considered as one of the best means of to an Improved Bottom Line: separating liquids and solids, whether the process calls for inverting, vertical or horizontal centrifuge technologies. Step 1: However, many centrifuges operate below their design Mechanical checks of the centrifuge include: Mechanical capacity due to incorrect operation, inefficient process inspection (O-rings, seals, bearings etc); Filter cloth selecparameters, or wear and tear on the machine over time. tion specific to product – critical and frequently incorrect Together with their partner, Contecma C.S Gmbh, load cell calibration. CPI Technology can deliver significant yield and efficiency increases from your centrifuge by closely analysing and Step 2: implementing the centrifuge mechanics, process paramCollation and analysis of process conditions and definition eters, automation and machine fine tuning. of new parameters – this is typically based on historical information and is not optimised for the latest production Process Optimisation products and demands. Some aspects in the optimisation process include reviewing: There are many types of centrifuges in operation in the • Program settings pharmaceutical and chemical industries in the API indus• Wash ratios 14


Cover Story

• • •

Figure 1: Typical Particle Distribution Curve Products with more than one peak in the particle distribution curves are more difficult to feed into a centrifuge, due to the possibility of separation between the larger and smaller particles.

Capacity Product data New program creation with identified parameter modifications

Step 3: Test runs, process fine tuning and measurable results in euro. • Confirmation of new program parameters • Higher yield • Dryer product • Reduced cycle times • Improved wash process

The Separation Process Production Centrifuges typically operate between 1000 and 2000 times G-force, with the result that filtration is 1000 to 2000 times faster than filtration with a funnel. The average particle size of separation in a filter centrifuge is between 5.0mm and 0.1µm. The use a filter centrifuge for particles less than 0.1µm is impractical due to the limitation of effective filter cloths. During the centrifugation / separation of a product there are several stages.

Figure 2 An integral part of the optimisation process requires determination of the optimum fill speed and flow rate in order to build up a homogenous filter cake. This can include multiple fill steps at varying fill speeds. Understanding the particle size and the particle form (crystalline, amorphous, needles etc) is important for the efficient operation of any centrifuge and is necessary for accurate calculation of the process parameters required to deliver improved yields. Solids concentration, particle distribution, fill speeds, flow rate and cake thickness all affect the next steps of the washing and centrifugation of the product.

Charging The first stage is to charge the centrifuge with the slurry and this is the most important step. During this stage, the filter cake is created. The slurry flows continuously into the centrifuge, forming the cake, while the mother liquid is drained off - process optimisation demands determination of the ideal cake thickness for an effective filtration rate of mother liquid. Solids distribution and concentration are critical for efficient cake building (see Figure 1 – Typical Particle Distribution Curve).

Washing In order to optimise the wash step, it is important to understand the reason for washing in the first place. There are generally two different reasons. One is to remove the impurities from the mother liquid - or to displace the mother liquid from the filter cake. The second reason may be to wash a secondary product out, such as a salt or a pH from the filter cake. During the wash optimisation step, it is important to understand whether the wash is more time dependant or wash volume dependant. Detailed analysis of the wash program can lead to reduced wash times, reduced wash volume or both. (e.g. products capable of being washed with steam instead of water can see wash volumes reduced by a factor of 100 or more).

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Centrifugation The Centrifugation stage normally occurs after the charging of the slurry and before the washing. Once the washing stage is complete, the final centrifugation step starts and this is where analysis of the centrifugation process provides optimisation of the cycle time and centrifuge speeds. With PAC (Pressure Added Centrifugation) examination, regular spinning time can be reduced by up to 50%, depending on the product. A secondary benefit of the PAC spinning time is the reduction of the moisture content: with optimised conditions of the PAC spinning cycle a moisture content of less than 1% can be achieved.

Filter Dryers Agitators

Summary Centrifuge optimisation requires all process parameters to be considered. Temperature affects viscosity, speed affects cake building, cake thickness affects filtration rate, filter cloth determines particle retention – and so on. Process optimisation is a complex procedure and requires in-depth process expertise in order to obtain the highest yield from the product you produce, together with obtaining the best quality and the driest product from your centrifuge. CPI Technology, in partnership with Contecma C.S Gmbh, are at your service to gain these results and increase profits for your company. With experience of more than 500 different chemical and pharmaceutical products and applications, Contecma C.S Gmbh has many years experience of centrifuge maintenance, refurbishing and optimisation. “CPI Technology’s successful long term partnerships with leading global clients is evidence of our on-going commitment to service,” summarises Colin Corbett, API Technical Specialist and Support, CPI Technology Ltd. “We emphasise personal involvement, responsiveness and reli-

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ability in our daily interactions with our customers and we consistently strive to deliver leading edge technologies that meet and exceed our customers expectations at all times.” For more information, please contact: Colin Corbett, API Technical Specialist and Support, CPI Technology Ltd, Unit 5, Link Road Business Park, Ballincollig, Co. Cork. Tel +353 (0)21 4874142 Fax +353 (0)21 4878764 E-mail: info@cpitechnology.com Web: www.cpitechnology.com

16


Solvents

Soltec: Ireland’s Only Commercial Solvent Distillers

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computer-controlled automated drum filling system for their product packaging department. Soltec’s strong team of technical employees is second to none, giving customers the assurance of quality throughout the production process. Environmental concerns are high on the agenda, with the company’s most recent appointment seeing a graduate of DIT’s Environmental Management Degree course taking on the role of On-site Environmental Manager. In addition Soltec has also built up a valuable network of waste management contractors and hazardous waste experts, which the company draws on in order to provide a high standard of service to customers. Specifically Soltec provide solutions in the following waste streams: Solid Waste: contaminated personal protective equipment, lab smalls, spray bottles, wipes, oily rags, crushed paint cans, glues, adhesives, wipes; Liquid Waste: inks, solvents, paints, primers, lacquers; “Our aim is to help companies reduce their waste management costs and transform waste into a valuable resource while complying with relevant waste legislation,” sums up Soltec’s David Corcoran.

STABLISHED in 1994, Soltec (Ireland) Ltd operates the only commercial solvent distillation facility in Ireland. Soltec has developed a strong customer base throughout the country, co-ordinated from its facility in Mullingar, Co. Westmeath Soltec are licensed through the EPA to accept up to 5,000 tonnes of waste organic solvents and recover them to a reusable product, through dry distillation technology. The recovered product is sold as ‘paint thinners’ and other industrial cleaning agents throughout Ireland and England. Soltec complies with the Waste Management Act 1996 and EPA Act 1992, which provide legislation goverening the tracebility and management of waste from ‘cradle to grave’. Soltec also are governed by their EPA Waste Licence (W0115-01) and ISO 9001 quality standard, while Soltec’s facility is managed under the ISO:14001 Environmental Standard. Soltec has invested in distillation and laboratory equipment, which provides the necessary elements to recover solvents to a specific standard. In 2011, Soltec invested in upgrading their scrubber system to further reduce air emissions. Soltec are also in the process of installing a

Hazardous Waste Managment Solutions • On Site Distillation Recovery • Recovery of Hazardous Solid and Liquid Waste • Suppliers of Recycling Equipment • EPA Licensed Waste Managment Facility

making waste work

Zone A Mullingar Business Park Mullingar Co. Westmeath Tel: 044 9335133 Fax: 044 9345248 info@soltec.ie www.soltec.ie

making waste work 17


Science Foundation Ireland

Research for Ireland’s Future Science Foundation Ireland (SFI) is committed to building a world-class research environment in Ireland, investing in research teams to generate new knowledge, leading edge technologies and competitive enterprises in the fields of science and engineering.

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INCE its establishment just over a decade ago, Science Foundation Ireland (SFI) has strategically invested over €85m in the pharmaceutical sector, from formulation through to drug delivery. A further €424m has been allocated by SFI over the same period in the biotech/biologics sector that underpins the pharma sector. Sustained strategic investment in these fields has been a major contributing factor in establishing Ireland as an internationally attractive location for multinationals. Today, nine of the top 10 global pharmaceutical companies have a presence in Ireland, with 11 of the world’s top 12 medical technology companies having a manufacturing base here. Ireland’s PharmaChemical industry generates over half of all Ireland’s exports, and we are now the largest net exporter of medicines in the world. This strong commercial track record has been mirrored by impressive academic rankings, with Ireland now in the top 20 countries in overall scientific global rankings, and especially strong in other fields such as immunology (where we are now ranked third). Ireland continues to broaden its pharmaceutical horizons, with many new opportunities for developing novel products and processes currently being explored. Working closely with IDA Ireland, Enterprise Ireland, the Health Research Board and others, SFI is actively engaged in a collaborative agenda to enhance and expand existing works streams and commercial outputs.

ulcerative colitis, and Crohns Disease. The APC has already seen the licensing of a probiotic treatment for Irritable Bowel Syndrome in the US through Procter and Gamble and has collaborations with multiple industry partners, including GSK. • The Solid State Pharmaceutical Cluster (SSPC) led by Kieran Hodnett at UL and with co-investigators located in UCC, NUIG, UCD and TCD, carries out associated research by finding methods to rationally design solid-state pharmaceutical materials in their required physical and chemical forms, through designing novel crystal synthesis and characterisation techniques and using theory and modelling to more clearly understand how best to produce tablets and other drug formulations (www.ul.ie/sspc). The SSPC has multiple successful industry partnerships with many of the world’s leading pharmaceutical companies, including Pfizer, Merck, GSK and Roche. • The Irish Drug Delivery Network (IDDN) Strategic Research Cluster (SRC) is led by David Brayden at UCD, with four co-PIs based in UCC, TCD and the RCSI (http://www.ucd.ie/iddn). The main thrust of the IDDN’s research is to investigate novel ways of replacing injected medicines with drugs based on proteins and genes, which are administered either orally or through inhalation. The IDDN has forged a successful partnership with the indigenous enteric drug delivery company Sigmoid Pharmaceuticals and has other industry partners, including Genzyme.

Pharma-Related Investments Some of the most significant SFI pharma-related investments include:

• The Alimentary Glycosciences Research Cluster (AGRC), a strategic research Cluster (SRC) led by Professor Lokesh Joshi, SFI Stokes Professor, is based at NUIG and is a consortium of researchers from NUIG, UCD, Teagasc, NIBRT and UCC, in addition to a number of industry partners tasked to explore the role of gut glycosylation in host-microbe interactions including Agilent Technologies (HTP

• The Alimentary Pharmabiotic Centre. This SFI CSET, based at UCC, is the flagship investment that has been made by SFI in gastroenterology. Their overall remit is to investigate the means by which intestinal bacteria influence health and disease and to this end, they work towards developing new therapies for lifelong debilitating gastrointestinal diseases such as gastroenteritis, 18


Science Foundation Ireland

Analytical Tech.), Alimentary Health (Probiotics and Pharmabiotics), Biomining, Inc (Biostatistical Analysis), Bristol Myers-Squibb (BioPharmaceuticals).

SFI Centres for Science Engineering & Technology (CSETs) – Life Sciences

Alimentary Pharmabiotic Centre (APC) at University College Cork - www.ucc.ie/research/apc The goals of the APC include investigating the means by which intestinal bacteria influence health and disease; developing new therapies for debilitating gastrointestinal diseases (such as gastroenteritis, C. difficile, ulcerative colitis and Crohn’s Disease); exploring commercial opportunities in both the pharma and functional food sector; and positioning Ireland at the forefront of this exciting new area. Collaborating partners: Alimentary Health, GlaxoSmithKline and Teagasc (the Irish agriculture and food development authority).

• The Molecular Therapeutics for Cancer Ireland Strategic Research Cluster is led by Professor John Crown. This cluster involves a consortium of scientists, including a number of clinical investigators, whose vision is to assemble and build a fully integrated national translational cancer drug discovery and development program for the benefit of cancer patients. Their goal is to identify biomarkers and targets, identify new indications for molecular targeted agents, understand the molecular basis for sensitivity/insensitivity to molecularly-targeted agents (MTAs), and find ways to monitor therapy. The therapeutic areas encompass breast, melanoma, lung and prostate cancer. Industry partners include Roche, Anti-Cancer Inc, Novartis, Amgen, Caliper Life Sciences, Merck Sharp & Dohme, GlaxoSmithKline, Erigal, and Pfizer.

The Future

for

Biomedical Diagnostics Institute (BDI), Dublin City University - www.bdi.ie BDI is carrying out cutting-edge research to develop the next generation of biomedical devices that will directly affect the quality of people’s lives worldwide over the coming decades. The diagnostic devices and sensors will aim to detect minute concentrations of disease related molecules in biological samples like blood, saliva and breath. Collaborating Partners: Åmic AB (recently acquired by J&J Ortho-Clinical Diagnostics), Analog Devices Inc., Becton Dickinson and Co., Biosurfit S.A, Enfer Technologies Ltd., Hospira Inc., Inverness Medical Innovations Inc., Millipore.

Research

Looking to the future, having received a strong endorsement in Budget 2011, SFI will continue to support and collaborate with our pharmaceutical-focused research-

Systems Biology Ireland, University College Dublin (http://www.ucd.ie/sbi/) Systems Biology Ireland will build the foundations of the science through the development of platforms and expertise in systems biology by focusing on defined scientific projects. In an effort to solve critical biological and biomedical problems, SBI research projects will be driven by the need to address biological questions for tangible benefits. In order to achieve a systems level understanding, the conceptual framework to rationalise complex biological relationships will come from mathematical modelling. Collaborating Partners: NUI Galway and industry partners Hewlett Packard, Servier, Agilent Technologies, Siemens Ireland, Ark Therapeutics and Protagen AG.

SFI Strategic Research Clusters (SRCs) – Life Sciences

• Reproductive Biology Research Cluster, Dr Alexander Evans UCD. • The Irish Drug Delivery Research Network (IDDN), Prof. David Brayden, UCD. • Network of Excellence for Functional Biomaterials (NFB), Prof. Abhay Pandit, NUIG. • Solid State Pharmaceuticals Cluster, Prof. Kieran Hodnett, UL. • Immunology Research Centre (IRC), Prof. Kingston Mills, TCD. • Advanced Biomimetics for Solar Energy Conversion, Prof. James MacElroy, UCD. • Alimentary Glycoscience Research Cluster (AGRC), Prof. Lokesh Joshi, NUIG. • Irish Separation Science Cluster, Prof. Brett Paull, DCU. • Molecular Therapeutics for Cancer Ireland (MTCI), Prof. John Crown (DCU).

ers and industry partners. In terms of policy, the new Programme for Government commits to targeting scientific research and development, and has identified areas such as bioscience as among those sectors with greatest scope for innovation. Furthermore, the Government has also pledged to refocus our overall R&D and innovation policy, as part of the European Commission’s ‘Innovative Union’ proposals, with a greater emphasis on turning inventions into products. Our scientific infrastructure and extensive network of personnel across enterprise and academia would suggest that Ireland has never been so well-equipped to play a leading role on the pharma stage. For more information about SFI-supported research and details of upcoming calls, go to www.sfi.ie. 19


Laboratories

Making In-Sourcing Work For You Lancaster Laboratories’ innovative, award-winning, in-sourcing solution helps GMP laboratories to address the upcoming EU Directive, writes Beth DiPaolo, Managing Director, Professional Scientific Staffing, Lancaster Laboratories.

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n today’s global economy, most companies are being forced to cut costs and control spending. For pharmaceutical and biopharmaceutical companies in particular, common practice is moving away from permanent worker contracts to avoid the associated long-term fixed costs. However, the alternative solution to replace these positions with temporary workers also now comes at a higher cost to companies in light of the new EU Temporary Agency’s Workers Directive 2008/104. Caught in the middle of these industry changes and employment legislation, businesses are struggling to find a balance between adhering to budget constraints and securing the resources needed to meet project demands.

to offer a unique service model, called Professional Scientific StaffingSM (PSS), to help alleviate headcount, co-employment, and management challenges. Lancaster Labs recruits, hires, trains and manages highly-qualified scientists to perform laboratory services at the client’s facility, using the client’s systems and equipment. These scientists are Lancaster Labs’ employees, managed by us, with the same benefits, including healthcare and pension, as any other employee. They are physically located at the client’s site, using the client’s systems, equipment, and standard operating procedures. But they are supervised by our on-site manager, who oversees the team, project, and budget. Lancaster Labs’ PSS approach solves the challenges surrounding the EU Temporary Agency Workers Directive, which comes into effect on December 5, 2011. Many clients view this as an ideal solution for a flexible workforce achieved at a lower cost than fixed headcount, with no concerns about co-employment management. Utilising the PSS program is more cost-effective than hiring full-time employees, and avoids the turnover rate and lack of productivity that is typically seen with temporary staffing programs. In addition, all of our PSS teams measure quality and productivity to drive continuous improvement and demonstrate value to our clients.

Cost-Effective In-Sourcing Solution The current dynamics of the pharmaceutical industry have created a need for a more flexible, value-added, cost-effective in-sourcing solution. Lancaster Laboratories combines GMP operational experience with proven HR practices

Adaptable PSS Model Whether a client is looking for a PSS team to complete a distinct type of testing, or they are seeking a specific skill set to perform the work, we can adapt our PSS model to meet the project needs. We can also work in tandem with the client’s teams or work independently from them to meet a wide array of testing needs. For example, Eli Lilly uses Lancaster Labs’ PSS program to perform environmental monitoring and water testing, using a team of 10 analysts and one group leader to carry out the required testing, managing their own work20


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Laboratories

loads and working independently from other Lilly staff members. On the other hand, another client uses PSS in a manner that blends their employees with our PSS team members to collaborate on projects. In this case, a team of five analysts, one lead analyst and one research investigator are spread throughout the site and work side-by-side in the same labs and offices as the client’s employees. The client’s managers oversee the company’s workflow and direct the Lancaster Labs’ PSS team members to where they are needed. Infusing our 50-year track record of scientific laboratory expertise and HR best practices with 10 years of proven success with the PSS service model, our staffing partnerships have grown to more than 350 employees, serving customers at 20 different sites in three countries, including Ireland, the US and UK, with project teams ranging in size from two to 89 team members. In addition, Lancaster Labs has been recognised with four strategic partner awards for exceeding our clients’ expectations with this program.

added, in-sourcing solution delivered by a highly reputable laboratory. By choosing an in-sourcing solution, companies can reap the benefits of meeting workload demands, while minimising headcount and other challenges associated with workforce management. If your organisation, like many others, is seeking a solution to help balance budget constraints while also meeting output and testing demands, consider PSS as your insourcing solution to help you accomplish your project goals in the most cost-effective, productive manner. For more information about Lancaster Laboratories’ PSS program or other services, visit: www.lancasterlabspharm.com.

About the Author: WITH Lancaster Laboratories’ Human Resources Department since 1987, Beth DiPaolo, MA, SPHR, is the Managing Director of Professional Scientific Staffing.

Balancing Budget Constraints By joining forces with Lancaster Labs, pharmaceutical and biopharmaceutical companies can receive a flexible, value-

536 Grants Crescent, Greenogue Business Park, Rathcoole, Co. Dublin Tel : + 353 1 4019800 Sales Office : + 353 1 4019817 E mail : pharma.sales@univareurope.com www.univareurope.com

Univar is Ireland’s leading source of high quality ingredients to the pharmaceutical sector. Our purpose built site has been designed to meet the regulatory compliance demands of our pharmaceutical customers. We are serious about safety and we are committed to making a positive impact on environmental issues in handling fine chemicals. Univar is the partner of choice for many of the world’s leading pharmaceutical ingredient manufacturers. Whether you are looking for API’S, EXCIPIENTS, PROCESS CHEMICALS, SOLVENTS, OR INTERMEDIATES we can provide technical and regulatory support.

To discuss your specific needs please contact our sales office at +353 1 4019817 22


Recruitment

Growth: How and Where It Is 2011 looks to be brighter for recruitment in the pharmaceutical and Life Science sector, according to the results of a new study by Berkley Group, writes Joanna Houston, EMEA Operations Manager, Berkley Pharmaceutical & Life Sciences, Engineering.

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HEN discussing the marketplace over the last few months, Berkley has encountered a mixed interpretation on the state of our economy at present. Based on this range of opinion, we undertook a study to quantify the views and opinions of the leading 80 Pharmaceutical/Life Science HR teams to determine expected trends in the second half of 2011. There was general agreement that things have improved since this time last year, with 71% of the respondents experiencing a growth in hiring in the first six months of 2011. On further examination of the skill-sets relating to this figure, we see more positive signs, giving more confidence in the areas mentioned. 12% said quality expanded, 24% named manufacturing but interestingly, R&D held at just 6%, while HR/IT/Finance came to 18% of the growth, suggesting a corporate openness to spending has returned. 18% of jobs were newly created positions, with 65% of the organisations questioned saying they had a mix of new and backfill roles. Alarmingly, 41% of hiring professionals stated that the quality of candidates was the biggest barrier to recruitment this year to date. This leads to the question whether or not we have to change the recruitment models, style of hire, job functions or expectations of a new employee? Head count approval was consistently featured by 29% of the respondents. In support of these statistics, Berkley Pharmaceutical and Life Science can confirm an increase in the requests for market analysis for Senior Management, particularly in the area of skills availability and cost of hire, analysed on an international basis.

Progressive Outlook

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Interestingly, the areas most effected by any planned downsizing were QA, manufacturing and capital projects. Our survey was based on the comments of those within the HR function, so further research into the availability of funding for capital projects will be conducted by Berkley Engineering later in the month. Manufacturing featured in the downsizing stakes at the top of the league table, but thankfully this should be balanced out by the growth planned in other organisations.

Broadening

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Candidate quality and availability, while it is listed as an area to improve by our industry leaders, it is also important to note that 71% of our audience have hired internationally this year. This statistic in isolation can be representative of the Irish R&D economy portrayed across the globe, but in factual terms, it gives rise to the question: do we have a broad enough skill base in the local market to serve the modern pharmaceutical and life science world with the changes in technology, manufacturing environment and typical hires? A major topic of discussion over the last few years has been the rise of upskilling programmes. One welcomed, due to the focus on technology and interpersonal skills combined, is that of InnoPharma Labs. Within Berkley Group’s European markets, we still see Ireland holding a steady pace against international trends, and we are encouraged with the amount of successful work being carried out by the IDA teams in Life Sciences, in the efforts to attract more quality FDI. In this arena, our Asian operations see the “on the ground” work carried out by the IDA internationally, and it has to be applauded.

Q4

Looking forward into Q3 and Q4 there is reasonable confidence that things will remain in a progressive state. 24% thought there would be a further increase in hiring, 35% thought it would decrease while 41% were unsure/not in a position to comment, due to reasons including the level of employees on long term leave, temp worker increases, no recruitment planned but things are in a changing and irregular pattern.

BERKLEY Group, consisting of Berkley Engineering, and Pharmaceutical & Life Sciences operates in Europe and Asia. They can be contacted at www.Berkley.ie Tel: 01-8724666 / 021 4289600.

23


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Pharmaceutical Packaging

One Small-Run for CPOs, One Giant Leap for Pharma! Pascal Keogh, MD of Millmount Healthcare, explains how utilising CMOs and CPOs as part of a long-term strategy can allow pharmaceutical manufacturers to adapt to the demands of the modern pharmaceutical industry, while helping to cut costs.

T

he Times They Are a-Changin’’ (Dylan, 1965): the theme song for Pharma in 2011? Never could a song capture the mood of the current state of affairs in the pharmaceutical industry like this one does. The pharmaceutical landscape as we know it is changing. The industry’s desire to reduce cost, innovate and commercialise value-added products demands new approaches to how it makes and delivers drugs . The once indomitable pharmaceutical giants have had to come to terms with the reality of no longer being able to rely on a pipeline of blockbuster brands to maintain their huge profits . The focus, it now seems, has switched to niche products, and the flexibility and capability to manufacture them. What role, if any, can contract manufacturing organisations (CMOs) play in this ‘Nouveau Pharma’ landscape? John Bolla (GSK) recently remarked, “There is a significant opportunity for contract manufacturers to help us and rationalise our manufacturing networks”. Indeed, for pharma companies big or small, outsourcing has always played a vital role – providing opportunities to lower scale-up and manufacturing costs, increase flexibility in terms of manufacturing capacity and eliminate capital costs associated with the launch of, and continued market demand for product. If we agree that CMOs have a vital role to play in the new pharmaceutical environmental – what role, if any, for a more specified branch of the CMO – the contract packaging organisation (CPO)? Pascal Keogh, MD of Millmount Healthcare, explains how his company’s commercial business model is adapting to the demands of the modern pharma-

ceutical industry – small run / late-stage customisation.

Pascal Keogh, Managing Director, Millmount Healthcare.

How would you assess the current plight faced by many organisations operating in the pharmaceutical industry? The pharmaceutical industry is faced with more challenges than ever before – strict legislation in the form of governmental price controls, an apparent lack of new blockbuster candidates, personalised medicine and patent expiry, with increased competition in the form of new generic entrants. As a result, the market share for the existing companies is drastically being reduced. There are increasing demands for smaller run sizes. Subsequently, there is a major focus on inventory control and wastage associated with short runs, regulatory change and short shelf-life products. What challenges, if any, do these changes in the landscape have on companies such as Millmount Healthcare? The contract manufacturing industry is one of constant change. It suffers or benefits from the stresses and strains of the pharmaceutical industry. Consequently, Millmount Healthcare must be flexible, and where possible, anticipate our partners’ requirements in order to exceed all their expectations. This has meant us adapting several of our lines to facilitate short-run, quick turnarounds. We work with our customers to standardise on pack layouts, so that the cost of cutter profiles are kept to an absolute minimum. We are also working with our suppliers to ensure competitiveness on short-runs. As a company, we have had to streamline our systems and procedures by introducing LEAN practices. Our definition of a small run is probably 25% of what

25


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Pharmaceutical Packaging

What additional advice can you offer manufacturers to improve efficiencies and/or reduce cost? Despite specialising in packaging and warehousing solutions, we have on occasion been sought after for advice and counsel by our partner companies. We are happy to provide this service, and would look for a solution to their packaging problems on a case-by-case basis. Pack lay-out is one area which can reduce the cost substantially. For example, 28 tablets in one blister typically cost half the price of two blisters of 14 tablets. Standardisation of pack design is another area which warrants further examination, with the potential to speed up changeover, both on packaging lines and component suppliers, leading to cost benefits.

Conclusion

we would have considered a small run several years ago. Down-time reduction and rapid changeover times remain key factors for driving efficiencies in this model.

The pharmaceutical landscape is well and truly ‘a-Changin’, with manufacturers being forced to re-think their operations and as a result, transform their approach to outsourcing. Rather than meeting the changing landscape with fear and trepidation, they must embrace the challenge and learn how best to build alliances with both CMOs and CPOs as part of a long-term strategy to alleviate their cost and R&D woes.

With cost becoming a critical deciding factor when choosing a contract packer, are you finding customers increasingly moving to non-European service providers? We are actually finding that the trend is starting to reverse. Although companies are still open to the idea of purchasing tablets/capsules from outside the European Union, there is a drive towards small scale / late-stage customisation within Europe. This allows them to closer match countrywide demand with bulk availability, with a typical conversion time from bulk to specific market livery within three weeks. It also means that analytical testing is reduced to testing on the bulk batch, as opposed to sub-batch testing for each market.

About Millmount Healthcare

So what does this mean for generic manufacturing in Europe – are we seeing the beginning of a decline in this area? There are ample opportunities for growth in the generics market, despite the fact that it is an extremely costconscious area. The market dynamics here focus on being first-to-market, with fierce competition, and fast attrition in market share. I believe that we are seeing the beginning of a trend, whereby large-scale manufacturers are focusing on core competencies, whilst realising that outsourcing has the potential to deliver excellent business value, beyond simple cost savings and operational flexibility. They are breaking down production runs to large and small series and on the whole, are focusing on tablet manufacturing and large series runs internally, giving them extremely competitive costs of goods, while outsourcing the small series runs to companies better geared for this type of work. Millmount Healthcare has the necessary systems in place, along with compatible machinery and tooling, to form a seamless extension to our partners’ current manufacturing practices. Our partners can typically expect to enjoy reduced cycle times, costs and resources associated with packaging, while maintaining control of information.

EXPERTS in contract packaging operations, Millmount Healthcare provides an effective outsourcing strategy from 3 cGMP compliant, Irish Medicines Board (IMB) approved manufacturing facilities. Major pharmaceutical and healthcare manufacturers use Millmount Healthcare for their blister packaging, bottling and warehousing requirements to achieve high-quality results with lower overheads. The company also acts as a European site of importation for non-EU products. Millmount Healthcare Block 7 CityNorth Business Campus Stamullen, County Meath Tel: +353 (0)1 841 8300 Fax: +353 (0)1 841 8039 Web: www.millmounthealthcare.com Twitter: www.twitter.com/MillHealthcare 27


Research & Development

Towards A National Pharma Competence Centre PharmaChemical Ireland has identified five key research areas, which will provide opportunities for the industry to make Ireland a global pharma centre of excellence, writes Nessa Moyles, Senior Executive, PharmaChemical Ireland.

P

harmachemical Ireland would welcome the creation of a National Pharma Competence Centre, encompassing small and large molecules. Our vision is one centre for the sector consisting of FDI’s and SME’s, harnessing all of the resources available in the HEI’s. A pharma competence centre would assist the Irish pharma sites to become or maintain their position as the “site of choice” within their global site portfolio. We live in challenging times and the sector is acutely aware of the specific challenges it faces, including patent expiration, diminished volume from research pipelines and global consolidation. In order to combat these threats, PharmaChemical Ireland has identified five key research areas, which will provide opportunities for the industry to make Ireland a global pharma centre of excellence. A centre encompassing both biopharma and small molecule technologies would be unique globally and would closely mirror industry trends. The five key research areas identified include:

the potential to become a global leader in Biocatalysis technology, leveraging on skills acquired in biopharmaceutical and small molecule manufacturing. In addition, there is significant activity and capability within Ireland’s research institutes and SME’s, in this space. Biocatalysis is already taking place in some facilities, with the expectation that it will increase as products from R&D groups progress towards launch stage. Biocatalysis presents Ireland with a great opportunity to lead in the area of green environmental sustainability.

2. Continuous Processing Modelling

with

The pharmaceutical industry in Ireland has largely evolved during a ‘Batch Manufacturing Platform’ paradigm, resulting in most of our installed manufacturing facilities, technical support and regulation, being highly geared towards the batch based platforms. The industry is now moving towards ‘Continuous Processing Platforms’ that have proven successful in other industries, such as petrochemicals and fine chemicals. An Irish centre of excellence for continuous manufacturing, supporting the application of Continuous Manufacturing concepts into the Irish pharmaceutical industry, could enable the batch to continuous manufacturing paradigm shift to occur within our batch manufacturing sites for the next generation products.

1. Biocatalysis / Biopharma / Chemistry / Green Chemistry With eight out of the top 10 major international API companies having manufacturing facilities here, Ireland has

3. PAT/QbD

with

Modelling

Current available technology can often be expensive and not robust to operate on an ongoing basis as process control. An interest in identifying/ developing alternative technology that is robust and less expensive is desirable. Graduates are not presently knowledgeable or skilled in the area of QbD and specifically in DOE - this is a gap that needs to be addressed. There may also be a lack of skill / expertise amongst graduates in data modelling. The development of this expertise has a number of potential applications in gathering process data and using 28


R e s e aBr icoht e&c hDneovleolgoyp m e n t

QbD centre of excellence with supporting analytical capabilities would have global recognition (best practice on how to perform QbD and apply LEAN methods to research).

Playing

to

Our Strengths

PharmaChemical Ireland views the establishment of such a centre as critical infrastructure which will play to our key strengths: • A unique concentration of world leading manufacturing; • World class facilities in universities and IT’s; • A critical volume of talented PI’s and Post Docs in our HEA facilities; • A good volume of SME’s with an excellent track record; • A strong willingness to work together across companies, academia and Government. PharmaChemical Ireland has identified research being carried out at present in Ireland under all five headings, in addition to indigenous Irish companies working in this space, all of which, combined with such an infrastructure, will best position the Irish pharma industry for the challenges ahead and maximise success for the future. The Pharma-chemical sector in Ireland is critical to the success of the Irish economy: • Eight of the top 10 multinational companies in the world have substantial operations in Ireland; • The replacement value of the sector is estimated to be €40 billion; • €350m investment on capital projects over the past 12-18 months; • Recent investments range from plant upgrades to new Greenfield facilities; • 25,400 employed directly, with the same number employed indirectly; • €47.2 billion exports (2009); • €1 billion per year in corporation tax contribution.

that data to predict performance, in addition to making processes more predictable and in the scale up from lab/ kilo to manufacturing. A centre of excellence that would carry out “proof of concept” would be of value to participating companies, in addition to providing training and support to improve knowledge and capability within companies. Crucially, the centre could enable graduates to become knowledgeable and experienced in the application of PAT and data modelling.

4. Solid State Pharmaceuticals Ireland could host a critical mass of expertise and research programs in a Solid State processing centre of excellence, aimed at adding value and development of new products. It would enable second generation chemistry on new chemical entities and make processes more robust. In addition, it could drive down manufacturing cost and extend product lifecycle with formulation development approaches. The centre would, of course, leverage from existing infrastructure in Ireland (such as the Solid State Pharmaceutical Cluster based in UL) and connect with existing centres in the UK (Strathclyde, Newcastle and Leeds) and further afield.

5. Analysis Research and innovation facilities involving specialist analytical services, next generation HPLC analysis, mass spectroscopy and bioanalysis will support plans for the pharma industry to move up the value chain and focus more on the higher value tasks, for example, R&D, clinical supply, product launch and second generation process development. In such instances, cutting edge analytical technology will be required to ensure those tasks can be supported in this country. An analytical centre of excellence can provide this support in multiple ways - by providing the industry with the services and by training graduates in the higher level analytical skill sets that industry can then hire directly. A 29


M at e r i al s H an d l i n g

Hyster Forklifts Develops Range Irish Lift Trucks has announced a host of new developments to its range of Hyster forlklifts and warehouse equipment.

I

RISH Lift Trucks, the exclusive distributor for Hyster materials handling equipment in Ireland, has announced several new developments to its range of Hyster warehouse equipment, delivering a low cost of operation and dependable, energy efficient performance for demanding operations.

ligently combines with vertical movements to ensure one of the quickest VNA transits in the industry. Common features include integral pantograph on the turret head and patented QUAD form mast design, which provides unmatched rigidity and torsional strength.

Reach Trucks

Low Level Order Pickers

In April 2011, Hyster announced changes to its Matrix reach truck series, including an increase in maximum traction speed of 8%. With no change between laden and unladen speeds, Hyster has achieved faster cycle times, especially over long distances, helping to reduce the cost of operation. Hyster Intelligent Design provides ease of control, giving superb narrow aisle manoeuvrability. It features 180° or 360° progressive steering, powerful acceleration and braking torque, seamless change in travel direction and automatic speed reduction on cornering. Hyster has also redesigned the overhead guard to optimise visibility and the series features a new full suspension seat.

The new LO2.0-2.5 low level order picker from Hyster has been developed to optimise the speed and ease of picking from both sides of a warehouse aisle. The intelligent design combines energy efficiency, reliability and ergonomics to achieve excellent operator pick rates and low cost of operation. One of the most notable design elements is the ‘man to goods’ proximity and the comfortable work platform with reduced height that helps minimise movement and saves valuable time in the picking operation. The large platform provides more space and allows easier pass-through with easy on/off access.

High Level Order Pickers

Pallet, Stacker

The Hyster K series of rising cab order pickers is designed to allow the best use of warehouse space and maximise pick face access at medium and high locations. The K series may be guided or non-guided: however, guided travel (rails or wire guidance) allows simultaneous lift and horizontal movement.

and

Tow Trucks

A complete range of Hyster pallet trucks and stacker trucks deliver reliability, power and precision, enhancing the operator’s productivity when transporting, stacking or de-stacking with a low cost of operation. Hyster has also introduced a tow truck to its range, which is suitable for supplying material to production lines, making it ideal for any type of line feed operation.

VNA

Electric Counterbalance

Hyster very narrow aisle (VNA) trucks enable operators to optimise storage capacity and efficiently retrieve pallets in high intensity operations. Horizontal movement intel-

The JXN(T) series of three and four wheel electric counterbalance trucks delivers class leading manoeuvrability 30


Loads more efficiency

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A member of

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Materials Handling

and the best balance of energy efficiency and productivity to suit demanding applications, with exceptionally low maintenance requirements. Lift capacities start at 1.5 tonnes and Hyster has recently extended the range to include 4-5 tonne capacities.

Options

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Explosion Protection

Hyster equipment is available in a range of options and configurations to suit specific applications. As some pharmaceutical facilities operate with classified hazardous areas, Hyster equipment can be supplied with Pyroban protection to ATEX 94/9/EC and supported by fully trained engineers. In short, ILT supplies the most complete forklift available on the Irish market today renowned for reliability, performance and helping reduce operating costs. The product range includes diesel, gas and electric Counterbalance forklift trucks, manufactured in Ireland, as well as warehouse equipment including Powered Pallet Trucks, Order Pickers, Reach Trucks and VNA Equipment, large capacity forklift trucks and containers handling equipment. They offer nationwide service support and all makes replacement part availability, as well as short term and long

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32


C h e m ica l D i s t ri b u t i o n I r e l a n d

Promoting Best Practice Nessa Moyles, Director, Chemical Distribution Ireland, explains the work of Chemical Distribution Ireland in the realm of industry best practice and responsible care.

C

Responsible Care

HEMICAL Distribution Ireland (CDI), formerly the Irish Chemical Marketers Association, was established in 1994. CDI is affiliated to IBEC and is a member of the FECC, the European Association of Chemical Distributors. CDI is the leading representative body for the chemical distribution industry in Ireland. Membership of CDI demonstrates the member company’s commitment to best practice in chemical distribution and ongoing responsibility in areas of product stewardship, safety, environment and quality. Members of CDI work to provide secure supply chains from producers to users and act as a valuable partner for material sourcing, storage and delivery. The main aim of CDI is to promote, support and encourage the further development of the multinational and indigenous chemical sector in Ireland. CDI achieves this by building and maintaining excellent relations and a positive profile with Government, public agencies, other representative organisations, international bodies and other interested parties.

CDI members follow the guiding principles of Responsible Care (using the assessment tool SQAS Distributor ESAD). These assessments are mandatory for membership. SQAS Distributor ESAD is a document developed jointly by chemical suppliers and distributors for use in one single assessment of distributors. It includes health, safety, environmental and quality aspects. There are also sections which cover the principles of GTDP (Good Trade & Distribution Practice). Trained assessors conduct assessments. Associate members, who are service providers to CDI members in the area of warehousing and transport, are required to undergo a relevant SQAS assessment such as SQAS Transport or SQAS Warehousing. CDI members must sign up to the eight guiding principles of Responsible Care: • Legal Requirements • Management of Risk • Policies and Documentation • Provision of Information • Training • Emergency Response • Ongoing Improvements • Community Interaction

Independent Audits The Responsible Care Working Group was one of the first to be established, following the formation of the association. It set up a number of minimum standards which members were required to meet as part of their conditions of membership. However, it was not until it reached an agreement with PharmaChemical Ireland (PCI) and the European Chemical Industry Council (CEFIC) on the use of the Responsible Care trademark and logo that the work began. It was recognised at an early stage that a mandatory system of independent audits, to be assessed and based on requirement of continuous improvement, would be needed to give the program credibility. In 1999, all members underwent a Phase I audit (SQAS ESAD I) which was accredited by the national employers body, IBEC. In 2007, preparation began for a Phase II audit (SQAS ESAD II) which was carried out by an independent auditing authority. Each member company delegates a Responsible Care coordinator to attend meetings.

“Responsible Care is the chemical industry’s own, unique initiative - a voluntary programme that helps it to raise its standards and win greater trust from the public. Under Responsible Care, the worldwide chemical industry is committed to continual improvement in all aspects of health, safety and environmental performance and to open communication about its activities and achievements. Responsible Care is more than a set of principles and declarations. Through the sharing of information and a rigorous system of checklists, performance indicators and verification procedures, it enables the industry to demonstrate how it has improved over the years and to develop policies for further improvement. In these ways, Responsible Care helps the industry to gain the trust of the public and to operate safely, profitably and with due care for future generations” - CEFIC. For more information, see www.chemicaldistributionireland.ie 33


Live Events

Maximise The Impact of Your Live Events Paul Smith, Irish Sales Manager, Clip Exhibition and Display, explains how his company can take the stress out of organising live events.

A

3) There needs to be refreshments supplied for everyone at the event. Interesting! Refreshments aren’t really my thing but how difficult can it be to order some coffee and cookies? I’ll get some top quality refreshments in to really hammer home the quality of our brand – 4/10.

re you a nervous person? Give the following scenarios a mark out of 10 regarding how nervous you would be in these situations, with 0 being totally confident and 10 being the most nervous you could be. I’ll put my own scores and thoughts down so you can see how we stack up against each other. 1) You are tasked with organising a small graphic display the size of an ice cream van in your company reception. That’s easy. It’s what I get paid for, no need for nerves. Just need to understand the key objectives of the display and make sure it’s “punchy” and to the point 1/10.

4) You need plasma screens running your corporate presentations too and internet access. You’re not the IT person but all they would suggest is switch it off and switch it back on again. It will be a great opportunity to get our new information out there on the plasma screens – 5/10.

5) All of your own company employees are going to be there. Wowzers! That’s going to be tough, but at least they’re all on my side and will be wishing me well….. well apart from Sophie in Human Resources who has had it in for me since the Christmas party 2009 for obvious reasons – 6/10.

2) The small display has been upgraded to a large conference area the size of a tennis court in a local hotel. That’s changed things a little but still no great problem. I need to find out the exact space and the location within the main hall so I can maximise my impact – 3/10.

6) All of your competitors are going to be there with their own presentation and you know that they will all have pushed the boat out. Ah, now that’s really stepped it up a notch! Let’s take the opportunity to hammer home our own USPs and really let people see that we can offer extra benefits over the competition – 8/10. 7) And all of your potential clients and prospects will turn up too to judge you directly against every other company in the room. Right then! This is where I really earn my money. I need to remember that we’ve got nothing to be afraid of. It’s the competition who should be nervous putting themselves up against us. Having said that, the nerves are inevitable – 9/10.

A large percentage of Clip Exhibition and Display’s business comes from eight of the top 10 pharmaceutical companies in Ireland.

34

If the above scenario sounds familiar, then you must be responsible for organising some of your company’s live events and therefore, I


Live Events

think you’ll agree that organising them is a tough job! To be honest, it’s a pressure that very few other roles in your company will have. Other roles are tough, of course, and bring their own pressures but live events are just that…..LIVE. When the doors open and the visitors walk through the door, there’s no chance to hit the pause button and make any changes. There’s no “version 3” or next draft. It’s lights, camera and action!

30 Years

of

Exhibition Stand Building Experience

I know the stresses and strains of exhibiting well, as I work for Clip Ireland, part of the Clip International group. With offices in Ireland, Germany, Belgium, UK and a worldwide distributor network, Clip have been at the forefront of the European exhibition and display business for over 30 years. We have built our reputation by taking pride in high quality standards, understanding our clients’ exhibition and display needs, and continuously aiming to exceed expectations. Our pedigree and commitment is there for all to see in the exhibition stands that we create today. We employ over 50 staff members in our UK and Irish operations. In 2010 alone, we built over 600 stands in venues from the RDS to Cape Town, from the Maldron Hotel, Killarney, to Dubai: we understand the stresses and strain of exhibiting and it is our job to take those stresses away from you.

Leaders

in the Irish

As Europe’s leading exhibition and display manufacturer, Clip are constantly developing and improving their innovative product range.

have worked with Clip Ireland for many years, and they utilise various services we can offer, such as Stand and Graphic Design, Build and Breakdown of Stands, Storage and Transportation of Stands/Display Products and Hire of Various Stand Components, as required. Next time you have a live event or exhibition, please get in touch to help us take away the stress and strain of the event. In brief, we can help in every way: • Understand your exact event objectives to ensure that we help you maximise your pre-show marketing;

Exhibition Marketplace

• Help set the measurable objectives for the event, to ensure you maximise the return on your investment;

As Europe’s leading exhibition and display manufacturer, we are constantly developing and improving our innovative product range. As all products and services are handled ‘in house’, we can maintain strict control over production and quality. We are proud to offer a total one-stop-shop solution, from portable kits and graphics to large stands and hire, and because we handle every part of the process in-house, we can guarantee that whatever your requirements, it will be problem free. An office was set up here in Ireland in 2004, in order to cope with the huge demand for our products and services from a range of Irish based companies. Our Irish business has grown and developed every year since 2004, and we are proud to have worked with over 3,500 different companies in Ireland, ranging from multinational pharmaceutical suppliers to hotel chains, shopping centres, Government bodies and agencies, sports organisations and many more.

• Our free stand design service will ensure that the physical elements of your brief are met; • Give stand manning training so that your staff know how the stand needs to be run to get the most out of it; • Help you manage your post-show follow-up, to make sure you have the return on investment that you were looking for; • Use our network of worldwide subsidiaries and distributors so that wherever your event is taking place, we are your local stand contractors; • Make use of the most modular and versatile exhibition stand system on the market. A system likened to “adult Lego” that can be reconfigured for all of your live events, giving you maximum return on investment and minimum on cost. The more events you attend, the cheaper the system becomes.

Supplier to Eight of the Top 10 Irish Pharmaceutical Companies A large percentage of our business comes from eight of the top 10 pharmaceutical companies in Ireland. We provide a range of products and services to these companies, including a wide selection of display products, as well as designing and building various exhibition stands, both here in Ireland and across Europe. Many of these companies

For more information please contact us on Freephone 1800 303438 or email paul.smith@clipdisplay.ie. Alternatively please visit our website at www.clipdisplay.ie.

35


www.prosys.ie

Process Containment Isolators

Laboratory scale to Small scale to Production scale

Charging Dispensing Off-Loading Filling Seeding Sampling Contained Process

Erecting

Inverting

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Palletising

Bag-in-Box

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Conveying

AGV Transport

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sales installation service G

G

T/F: 067 37893 087 1222816 info@goliath.ie www.goliath.ie BEECHWOOD, NENAGH, CO. TIPPERARY

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Pharmaceutical, Biopharma & Nuclear


C o n t a i nm e n t T e c hn o l o g y

Containing Hazards at Source ProSys is on course to become the preferred supplier of Custom Containment Equipment to the pharmaceutical production industry worldwide.

P

roSys Containment & Sampling Technology specialise in the design and manufacture of both Positive and Negative Pressure Containment Isolators, Gloveboxes, Downflow Booths, Restricted Access Barrier systems (RABs) and sampling solutions to meet the ever changing requirements of the pharmaceutical industry. Their products include both standard and custom engineered containment solutions. The company was founded in 1997 to supply specialised sampling solutions to the pharmaceutical industry. Over the last five years, ProSys has expanded rapidly by designing and developing a range of Containment Isolators. Their vision is to be the ‘Preferred Supplier’ of Custom Containment Equipment to the global pharmaceutical production industry.

Containing Hazards Source

at

Their philosophy is to contain any hazard at source, minimise cleaning, maximise flexibility and maintain an environment that is safe for all personnel. Depending on the application, the optimum solution will be achieved by the use of primary and secondary containment strategies or by combining a number of different techniques and technologies. All of their designs have been fully tested and qualified to contain potentially hazardous material to extremely low Operator Exposure Levels (OELs), whilst still retaining the flexibility that is required by the end user. ProSys Containment and Sampling technology provide complete turnkey solutions from initial Concept Design to In-house Manufacture and Functional and Containment Testing to On-site Qualification, Operator Training and Maintenance.

New Manufacturing Facility The company headquarters is based in Cork, placing it in a central cluster of top pharmaceutical global players, such as Pfizer, GSK, Novartis, Janssen, Lilly etc. A new manufacturing factory is currently under construction at the IDA Industrial Park in Carrigtwohill, Co. Cork, which will include a dedicated clean room. ProSys currently has sales offices in Liverpool (UK), Lille (France) and New Jersey (USA) and expects to open an office in Germany later this year.

Cost

of

Ownership

Life Cycle Cost Analysis allows ProSys to examine costs from inception to conclusion and to offer different design making alternatives to achieve the lowest cost of ownership. Indeed, ProSys recently completed a containment project for a secondary production facility that involved designing an isolator around an existing encapsulator machine. A team of client engineers and operators travelled from the USA to carry out ergonomic trials, then design review and finally FAT with OEL testing. The project included moving and rewiring the electrical control centre, while maintaining the original integrity of the mechanical encapsulator machine. The end result: the owner saved $1m by choosing to upgrade rather than purchasing a new machine. See www.prosys.ie for more information.

37


Innovative packaging solutions for the pharmaceutical and healthcare industries • Cartons • Leaflets • Labels • Printed foils for blister packs Contego Packaging Unit 629, IDA Industrial Park, Northern Extension Old Kilmeaden Road, Waterford, Ireland Please contact Maria Moran Business Development Manager T +353 (0) 51 595300 M +353 (0) 87 9885913

www.contegopackaging.com

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P ac k a g i n g

The Complete Package Contego Packaging supplies the pharmaceutical industry with cartons, leaflets, labels and blister pack foils from 10 sites across Europe, including their plant in Waterford.

F

ollowing the recent acquisition of Nampak Paper Holdings Limited by Platinum Equity, a rebranding exercise has resulted in a new name and identity for the business. Since June 1, 2011, the company has been renamed Contego Packaging. Contego is the Latin word to ‘protect, shield, cover and defend’, mirroring the company’s commitment to supplying customers with high quality packaging for their products. A pan-European campaign is currently underway to roll out the new name, encompassing everything from signage to stationery.

for pack insertion on high speed lines. Leaflets are printed on offset litho presses and supplied to customers flat, folded or crossfolded. Folding is determined by customer specification and pack size; the folded leaflet is suitable for high volume batches, whereas the flat option allows for smaller quantities.

Cartons In addition to leaflets, Waterford also produces over 200 million high quality cartons each year in a wide range of styles, constructional designs and graphical print finishes, onto different substrates and thickness of material. There is also the facility to provide performance varnishes, security and tamper-evident features and Braille embossing. The latest computer-to-plate technology is used in the prepress process, ensuring the highest quality print, with their stringent quality system, ISO 9001:2008 delivering 100% control from origination to final production.

A New Era “Our new name and identity mark the beginning of a very exciting era for our business,” explained Tom Reid, Chief Executive Officer, Contego Packaging. “We have already made some significant announcements regarding investment in plant and technology, including a new facility that will replace and upgrade our current factory in Portsmouth, which is scheduled to be fully functional by the end of 2011. Further developments are also in the pipeline for investment and improvement at our sites across Europe. “As ever, our commitment to providing our customers with the highest quality products and service remains top of our agenda”. Contego Packaging supplies the pharmaceutical industry with cartons, leaflets, labels and blister pack foils from 10 sites across Europe.

Product Portfolio Working in conjunction with customers and with other Contego sites located across Europe, a comprehensive range of self-adhesive labels and foils for blister packs can be supplied to complement leaflets and cartons produced at Waterford. Supply solutions can also be delivered to meet individual requirements, including supply chain management and Just-In-Time deliveries.

Leaflets

For further information, please contact Maria Moran, Business Development Manager, Contego Healthcare Waterford, tel: +353 51 595300, mobile: +353 87 9885913 Email: maria.moran@contegopackaging.com

One of Contego Packaging’s print facilities for leaflets for the pharmaceutical and healthcare industries is located in Waterford, where state-of-the-art printing and folding technology provides accurately folded, high quality leaflets 39


Dawsonrentals | temperature control solutions Purpose Built Cold Stores offering Flexibility and Reliability

• • • • • • • •

Temporary or longer term hire 4 pallet to 39 pallet capacity Single or dual refrigeration system -40°c to +50°c temperature range Door options available Ground level or loading bay level Can be sited inside or outside Upgrade Facility

Dawsonrentals Ireland Ltd. Unit 20, Toughers Business Park, Newhall, Naas, County Kildare Tel: 045 448810 Email: info@dawsonrentalsireland.com Web: www.dawsongroup.co.uk

SUPPLIERS OF:

ACETATE ESTERS

ETHANOLAMINES

LABORATORY CHEMICALS

ACIDS & ALKALIS ANTIFREEZE / GLYCOLS BLENDING - LIQUID/DRY CIP DETERGENTS

EXCIPIENTS FATS & WAXES FRAGRANCES & FLAVOURS GLYCOL ETHERS / ESTERS

PETROLEUM JELLIES / WHITE OILS PHARMACEUTICAL SPECIALITIES POLYETHYLENE GLYCOLS SALT - ALL GRADES

CONSUMABLES

GLYMES

SOLVENTS

CONTAINMENT PACKAGING ETHANOL

HYDROCARBON SOLVENTS KETONES

A LARGE RANGE

OF

MATERIALS CAN BE SOURCED TO YOUR SPECIFICATION

WE OFFER A WIDE RANGE OF CHEMICALS, SOLVENTS AND SPECIALITIES FROM REPUTABLE PRODUCERS Whatever your requirement please contact: Carol Deegan Carbon Group, Ringaskiddy, Cork Mobile: 086 2612 485 Fax: 01 628 9379 Email: carol.deegan@carbon.ie Email: sales@carbon.ie Website: www.carbon.ie

MEMBERS WORKING FOR THE ENVIRONMENT


Portable Cold Storage

The Bigger Chill Dawsonrentals Ireland offers high quality, flexible cold storage solutions, tailored to clients’ individual needs.

E

verybody strives to improve operational efficiency: Dawsonrentals Ireland can provide the cold storage flexibility that allows you to react promptly in a constantly changing business environment. Dawsonrentals pride themselves on their ability to listen, understand their customers’ wishes and provide a solution that makes their business more effective and therefore more profitable. “We understand the importance of improving your operation and now do so much more than simply off-load a unit and leave,” explains Aidan McCauley, Dawsonrentals. “Whilst we will supply a stand alone product, if that’s what is right for our customer, we are increasingly linking units and/or attaching units to the customer’s existing premises. The key is not the unit itself, but how it works for the customer.”

Dawsonrentals will always engineer their product to suit each individual customer’s needs. “In short, customers can look to Dawsonrentals for a tailored product which is supported by a premium service,” says McCauley.

Case Study Diversification for many companies is difficult, especially when there is the added need for large capital expenditure. A leading pharmaceutical provider successfully overcame these challenges by dramatically expanding their cold storage. The pharmaceutical company wanted to capture what they recognised to be an increasing business sector. A modular storage complex was supplied. The facility enabled them to double stack and rack stock, thereby providing twice the amount of storage space. Dawsonrentals’ units easily achieved strict -2 to +8°C chilled MRHA/FDA validated standards. Indeed, the customer’s continued success and demand from their growing customer base led them to request another duplicate complex, providing over 850m² of additional chilled storage space on site. Absorbing the costs of the facility into revenue, the pharmaceutical company were able to support the effective solution without a high capital investment. Furthermore, each facility was built, delivered, installed and subsequently serviced by Dawsonrentals. Dawsonrentals Ireland is part of Dawsongroup. Dawsongroup services include the rental, lease and contract hire of: trucks and trailers, temperature control solutions; buses, coaches and accessible vehicles; forklift trucks/materials handling equipment; industrial and municipal sweepers; display refrigeration and cold rooms; temporary kitchens and production facilities; as well as the provision of asset finance and leasing brokerage.

Design & Innovation The growth in design and innovation can be attributed to the infrastructure of ‘Team Dawson’, which includes both Project and Technical teams. “This is why we are able to deliver a solution with the characteristics and feel of a permanent facility,” McCauley continues. Dawsonrentals’ overall focus is on providing high quality, premium products and while some rental companies may only provide a set range of equipment for hire,

For more information, contact: Aidan McCauley Dawsonrentals Ireland Unit 20, Toughers Business Park, Newhall, Naas, County Kildare. Tel: (045) 448810 aidanmccauley@dawsongroup.co.uk www.dawsongroup.co.uk 41


C h e m ic a l S u pp l i e r s

Irish PharmaChem 2011

Chemical Suppliers Acids & Alkalis Associated Chemicals Ltd Brenntag Ireland Camida Ltd Carbon Group Chemco Ireland Ltd Chemsource Industrial Division Corcoran Chemicals Ltd Fisher Scientific Goulding Chemicals Ltd National Chemical Co. Ltd Ocon Chemicals Ltd P.K. Chemicals Ltd SciChem - Cork SciChem - Dublin Univar Ltd

Biochemicals Associated Chemicals Ltd Camida Ltd Corcoran Chemicals Ltd Fisher Scientific Ocon Chemicals Ltd

Biocides Brenntag Ireland Camida Ltd Fisher Scientific Univar Ltd

Catalysts Associated Chemicals Ltd Brenntag Ireland Camida Ltd Chemsource Industrial Division Corcoran Chemicals Ltd National Chemical Co. Ltd P.K. Chemicals Ltd

Chiral Compounds Associated Chemicals Ltd Brenntag Ireland Camida Ltd Waters Chromatography Ireland

Excipients Associated Chemicals Ltd Betco Marketing Ltd Brenntag Ireland Camida Ltd Carbon Group Chemsource Industrial Division Corcoran Chemicals Ltd National Chemical Co. Ltd Ocon Chemicals Ltd P.K. Chemicals Ltd Univar Ltd

Fine Chemicals Betco Marketing Ltd Brenntag Ireland Camida Ltd Carbon Group Chemco Ireland Ltd Chemsource Industrial Division Fisher Scientific National Chemical Co. Ltd P.K. Chemicals Ltd Univar Ltd

Gases Corcoran Chemicals Ltd

Heterocyclics Brenntag Ireland Camida Ltd National Chemical Co. Ltd

Inorganic Chemicals Associated Chemicals Ltd Brenntag Ireland Camida Ltd Chemco Ireland Ltd Chemsource Industrial Division Corcoran Chemicals Ltd Fisher Scientific Goulding Chemicals Ltd National Chemical Co. Ltd Ocon Chemicals Ltd P.K. Chemicals Ltd 42

SciChem - Cork SciChem - Dublin Univar Ltd

Laboratory Reageants Brenntag Ireland Carbon Group Fisher Scientific National Chemical Co. Ltd Ocon Chemicals Ltd SciChem - Cork SciChem - Dublin Waters Chromatography Ireland

Misc. Chemicals Associated Chemicals Ltd Brenntag Ireland Camida Ltd Carbon Group Chemco Ireland Ltd Chemsource Industrial Division Corcoran Chemicals Ltd Fisher Scientific National Chemical Co. Ltd P.K. Chemicals Ltd Ocon Chemicals Ltd SciChem - Cork SciChem - Dublin Univar Ltd

Oils, Fats and Waxes Associated Chemicals Ltd Brenntag Ireland Carbon Group Corcoran Chemicals Ltd Lister Machine Tools Ltd National Chemical Co. Ltd P.K. Chemicals Ltd Univar Ltd

Organic Intermediates Associated Chemicals Ltd Brenntag Ireland Camida Ltd Chemco Ireland Ltd Chemsource Industrial Division


Corcoran Chemicals Ltd Fisher Scientific National Chemical Co. Ltd Univar Ltd

Organometallics Associated Chemicals Ltd Brenntag Ireland Camida Ltd National Chemical Co. Ltd

Reagents Associated Chemicals Ltd Brenntag Ireland Camida Ltd Carbon Group Chemco Ireland Ltd Corcoran Chemicals Ltd Fisher Scientific National Chemical Co. Ltd

Ocon Chemicals Ltd SciChem - Cork SciChem - Dublin Univar Ltd Waters Chromatography Ireland

Silanes Camida Ltd Chemco Ireland Ltd National Chemical Co. Ltd P.K. Chemicals Ltd SciChem - Cork SciChem - Dublin Univar Ltd

Solvents Brenntag Ireland Camida Ltd Carbon Group Chemco Ireland Ltd

Notes

43

Chemsource Industrial Division Corcoran Chemicals Ltd Fisher Scientific National Chemical Co. Ltd Ocon Chemicals Ltd SciChem - Cork SciChem - Dublin Soltec (Ireland) Ltd Univar Ltd Waters Chromatography Ireland

Surfactants Associated Chemicals Ltd Brenntag Ireland Camida Ltd Carbon Group Corcoran Chemicals Ltd National Chemical Co. Ltd Univar Ltd

C h e m ic a l S u pp l i e r s

Irish PharmaChem 2011


Irish PharmaChem 2011

G e n e r a l S u pp l i e r s

General Suppliers Actuators Airpower Festo Ltd Flexachem Manufacturing Ltd Norgren Ireland Ltd Petrochem Pipeline Supply Ltd Tyco Valves & Controls Ireland Ltd

Aerators Manotherm Ltd WrenTech Ltd

Agitators CPI Technology Ltd Fisher Scientific Flexachem Manufacturing Ltd Quitmann O’Neill Packaging Ltd WrenTech Ltd

Air Filtration/Monitoring / Pollution Control Airpower Enva Ireland Ltd Norgren Ireland Ltd Ocon Chemicals Ltd SciChem - Cork SciChem - Dublin

Alarms P.J. Boner & Co. Ltd

Sartorius Mechatronics Ltd SciChem - Cork SciChem - Dublin Weber Labelling & Coding

Analytical Equipment

WrenTech Ltd

Biotechnology

Autoclaves Fisher Scientific Goliath Packaging Systems Ltd Ocon Chemicals Ltd SciChem - Cork SciChem - Dublin WrenTech Ltd

Brenntag Ireland Callaghan Engineering Catalent Pharma Solutions Flexachem Manufacturing Ltd H.R. Holfeld (Engineering) Ltd Ocon Chemicals Ltd SciChem - Cork SciChem - Dublin Waters Chromatography Ireland

Automation Airpower P.J. Boner & Co. Ltd Bosch Rexroth Ltd Callaghan Engineering Festo Ltd Flexachem Manufacturing Ltd Goliath Packaging Systems Ltd Norgren Ireland Ltd O’Flynn Medical Ltd Pilz Ireland Weber Labelling & Coding

Blenders Fisher Scientific Flexachem Manufacturing Ltd SciChem - Cork SciChem - Dublin WrenTech Ltd

Blistering / De-Blistering Catalent Pharma Solutions

Balances P.J. Boner & Co. Ltd Fisher Scientific Irish National Accreditation Board Ocon Chemicals Ltd Sartorius Mechatronics Ltd SciChem - Cork SciChem - Dublin WrenTech Ltd

Analysis Services Anecto Catalent Pharma Solutions Enva Ireland Ltd Lancaster Laboratories

Barriers Safety

Blowers Airpower CPI Technology Ltd Flexachem Manufacturing Ltd

BPRV BS&B Safety Systems Ltd

Barcoding/Labelling/ Traceability Airpower Flexachem Manufacturing Ltd Goliath Packaging Systems Ltd GS1 Ireland Millmount Healthcare

P.J. Boner & Co. Ltd Fisher Scientific Petrochem Pipeline Supply Ltd PPD Inc. 44

Bursting / Rupture Discs BS&B Safety Systems Ltd CPI Technology Ltd Flexachem Manufacturing Ltd


Cabinets Airpower Cross Technical Solutions Festo Ltd Fisher Scientific ProSys Containment and Sampling Technology Sartorius Mechatronics Ltd WrenTech Ltd

CAD Callaghan Engineering Waters Chromatography Ireland

Calibration P.J. Boner & Co. Ltd Dalkia Irish National Accreditation Board Ocon Chemicals Ltd Sartorius Mechatronics Ltd Waters Chromatography Ireland

Centrifuges CPI Technology Ltd Enva Ireland Ltd Fisher Scientific Sartorius Mechatronics Ltd SciChem - Cork SciChem - Dublin

Cleanrooms

Conveyors

Callaghan Engineering Carbon Goup Millmount Healthcare Pilz Ireland WrenTech Ltd

Clinical Reasearch Organisation HRB Clinical Research Facility Java Clinical Research Ltd

Cleaning Services / Equipment Goliath Packaging Systems Ltd WrenTech Ltd

Cold Chain Packaging Catalent Pharma Solutions CRS Mobile Cold Storage Millmount Healthcare

Compressed Air/ Compressors Airpower Cross Technical Solutions Festo Ltd Norgren Ireland Ltd

Bosch Rexroth Ltd Flexachem Manufacturing Ltd Goliath Packaging Systems Ltd Weber Labelling & Coding WrenTech Ltd

Cooling Systems CPI Technology Ltd Cross Technical Solutions Dalkia Dawsonrentals Irl Ltd

Data Acquisition P.J. Boner & Co. Ltd GS1 Ireland Manotherm Ltd Waters Chromatography Ireland Weber Labelling & Coding

Design Callaghan Engineering Cross Technical Solutions Graham Hart (Process Technology) Ltd Pilz Ireland ProSys Containment and Sampling Technology

Dispersers Chemical Consultants Carbon Goup Hazchem Training Ltd Pilz Ireland Soltec (Ireland) Ltd

Chromotography Carbon Goup Fisher Scientific Ocon Chemicals Ltd SciChem - Cork SciChem - Dublin Waters Chromatography Ireland

Condensors

Ocon Chemicals Ltd WrenTech Ltd

CPI Technology Ltd Cross Technical Solutions Graham Hart (Process Technology) Ltd

Condition Monitoring P.J. Boner & Co. Ltd CPI Technology Ltd Flexachem Manufacturing Ltd Dalkia

Distillation CPI Technology Ltd Flexachem Manufacturing Ltd Graham Hart (Process Technology) Ltd Ocon Chemicals Ltd Soltec (Ireland) Ltd WrenTech Ltd

Drains Construction Management Callaghan Engineering 45

Airpower H.R. Holfeld (Engineering) Ltd

G e n e r a l S u pp l i e r s

Irish PharmaChem 2011


Irish PharmaChem 2011 G e n e r a l S u pp l i e r s

Driers Airpower Complas Packaging Ltd CPI Technology Ltd WrenTech Ltd

Drums/Containers Carbon Goup Chemsource Industrial Division Complas Packaging Ltd Indaver Ireland Industrial Packaging Ltd Interpac Ocon Chemicals Ltd Quitmann O’Neill Packaging Ltd WrenTech Ltd

Electronic Components Airpower Pilz Ireland

Clip Ltd Ireland

Energy Efficiency / Management Berkley Group Callaghan Engineering Cross Technical Solutions Dalkia Flexachem Manufacturing Ltd Irish National Accreditation Board Sustainable Energy Authority of Ireland

Engineering Services Economic Development Agency Invest Northern Ireland

Education & Training Ann McGee CPI Technology Ltd Festo Ltd GS1 Ireland Hazchem Training Ltd Henley Forklift Group Ltd Pilz Ireland Waters Chromatography Ireland

Effluent Monitoring/ Treatment Axium Process P.J. Boner & Co. Ltd Carbon Goup Lancaster Laboratories Norgren Ireland Ltd Ocon Chemicals Ltd

Electrical Airpower Dalkia P.J. Boner & Co. Ltd

Exhibition Design & Display

Berkley Group P.J. Boner & Co. Ltd Callaghan Engineering Croom Precision Medical Dalkia Flexachem Manufacturing Ltd Henley Forklift Group Ltd Pilz Ireland

Environmental Consulting Callaghan Engineering Dawsonrentals Irl Ltd Enva Ireland Ltd Pilz Ireland

Environmental Services/ Equipment P.J. Boner & Co. Ltd Enva Ireland Ltd H.R. Holfeld (Engineering) Ltd Ocon Chemicals Ltd Pilz Ireland Quitmann O’Neill Packaging Ltd

Evaporators Cross Technical Solutions Fisher Scientific Flexachem Manufacturing Ltd Graham Hart (Process Technology) Ltd 46

Explosion Proofing BS&B Safety Systems Ltd Henley Forklift Group Ltd Norgren Ireland Ltd Pilz Ireland Sartorius Mechatronics Ltd

Explosion Protection / Panels BS&B Safety Systems Ltd CPI Technology Ltd Flexachem Manufacturing Ltd Henley Forklift Group Ltd Pilz Ireland

Extruders Flexachem Manufacturing Ltd WrenTech Ltd

Facility Design Callaghan Engineering

Facilities Management Goliath Packaging Systems Ltd Hochtief Facility Management

Filling Equipment Quitmann O’Neill Packaging Ltd Weber Labelling & Coding WrenTech Ltd

Filters Airpower Axium Process Carbon Goup CPI Technology Ltd Fisher Scientific Flexachem Manufacturing Ltd Norgren Ireland Ltd Ocon Chemicals Ltd WrenTech Ltd


Filtration Airpower Axium Process CPI Technology Ltd Enva Ireland Ltd Flexachem Manufacturing Ltd Norgren Ireland Ltd Ocon Chemicals Ltd SciChem - Cork SciChem - Dublin

SciChem - Cork SciChem - Dublin.

Gas Detection Fisher Scientific H.R. Holfeld (Engineering) Ltd SciChem - Cork SciChem - Dublin

Flexachem Manufacturing Ltd

P.J. Boner & Co. Ltd Fisher Scientific Flexachem Manufacturing Ltd Manotherm Ltd Norgren Ireland Ltd Petrochem Pipeline Supply Ltd

Flow Control Airpower P.J. Boner & Co. Ltd CPI Technology Ltd Enva Ireland Ltd Fisher Scientific Flexachem Manufacturing Ltd Manotherm Ltd Norgren Ireland Ltd Petrochem Pipeline Supply Ltd Tyco Valves & Controls Ireland Ltd

Glassware CPI Technology Ltd Fisher Scientific Ocon Chemicals Ltd SciChem - Cork SciChem - Dublin

Fluid Handling Hazardous Waste Disposal/Treatment Enva Ireland Ltd Hazchem Training Ltd Indaver Ireland Interpac Ocon Chemicals Ltd Quitmann O’Neill Packaging Ltd Soltec (Ireland) Ltd

Fume Cupboards Fisher Scientific SciChem - Cork SciChem - Dublin ProSys Containment and Sampling Technology WrenTech Ltd

Health & Safety/First Aid Fisher Scientific Hazchem Training Ltd Pilz Ireland

Heat Exchangers Furnaces Fisher Scientific

Homogenisers CPI Technology Ltd Fisher Scientific Flexachem Manufacturing Ltd SciChem - Cork SciChem - Dublin WrenTech Ltd

Hoses CPI Technology Ltd Flexachem Manufacturing Ltd Henley Forklift Group Ltd Micro Hydraulics Ltd/Micro Industries Ireland Norgren Ireland Ltd

Grinding CPI Technology Ltd

Callaghan Engineering CPI Technology Ltd Fisher Scientific Flexachem Manufacturing Ltd H.R. Holfeld (Engineering) Ltd Norgren Ireland Ltd Petrochem Pipeline Supply Ltd SciChem - Cork SciChem - Dublin WrenTech Ltd

Heaters Cross Technical Solutions

Gauges Fire Detection/Prevention/ Protection

Flexachem Manufacturing Ltd Graham Hart (Process Technology) Ltd Petrochem Pipeline Supply Ltd WrenTech Ltd

Axium Process CPI Technology Ltd Cross Technical Solutions 47

Humidity/Humidifiers Dawsonrentals Irl Ltd Fisher Scientific Interpac Manotherm Ltd

Hydraulics Bosch Rexroth Ltd Callaghan Engineering Henley Forklift Group Ltd Micro Hydraulics Ltd/Micro Industries Ireland WrenTech Ltd

Incineration Enva Ireland Ltd Indaver Ireland Soltec (Ireland) Ltd Tyco Valves & Controls Ireland Ltd

G e n e r a l S u pp l i e r s

Irish PharmaChem 2011


Irish PharmaChem 2011 G e n e r a l S u pp l i e r s

Incubators Fisher Scientific SciChem - Cork SciChem - Dublin Ocon Chemicals Ltd

Inspection Equipment P.J. Boner & Co. Ltd Flexachem Manufacturing Ltd H.R. Holfeld (Engineering) Ltd Sartorius Mechatronics Ltd

Instrumentation P.J. Boner & Co. Ltd Callaghan Engineering Fisher Scientific Flexachem Manufacturing Ltd Manotherm Ltd Petrochem Pipeline Supply Ltd Ocon Chemicals Ltd SciChem - Cork SciChem - Dublin Tyco Valves & Controls Ireland Ltd Weber Labelling & Coding

Technology Quitmann O’Neill Packaging Ltd Sartorius Mechatronics Ltd SciChem - Cork SciChem - Dublin Weber Labelling & Coding WrenTech Ltd

Legal/Financial/ Insurance MacLachlan & Donaldson Matheson Ormsby Prentice

Logistics C+G Logistics Group Chemsource Logistics KWE (Ireland) Ltd Movianto Ireland Weber Labelling & Coding

Investment Glanbia Estates Science Foundation Ireland (SFI)

Investment Promotion Agency IDA Ireland

Lab Equipment/Supplies

Dawsonrentals Irl Ltd Goliath Packaging Systems Ltd Henley Forklift Group Ltd Interpac Irish Lift Trucks WrenTech Ltd Toyota Material Handling Ireland Ltd

Mechanical Engineering Services Axium Process Berkley Group Callaghan Engineering CPI Technology Ltd Croom Precision Medical Dalkia Henley Forklift Group Ltd Goliath Packaging Systems Ltd Pilz Ireland Tyco Valves & Controls Ireland Ltd

Lifts & Hoists Airpower Goliath Packaging Systems Ltd Henley Forklift Group Ltd WrenTech Ltd

IT Berkley Group Callaghan Engineering Ocon Chemicals Ltd

Materials Handling/ Forklifts/Pallet Trucks

Machine Tools Lister Machine Tools Ltd Soltec (Ireland) Ltd

Maintenance Carbon Goup CPI Technology Ltd Cross Technical Solutions Dalkia Festo Ltd Flexachem Manufacturing Ltd H.R. Holfeld (Engineering) Ltd Goliath Packaging Systems Ltd Lister Machine Tools Ltd Sartorius Mechatronics Ltd Waters Chromatography Ireland

P.J. Boner & Co. Ltd Carbon Goup Fisher Scientific Ocon Chemicals Ltd O’Flynn Medical Ltd ProSys Containment and Sampling

Mechanical & Process Engineering Axium Process Callaghan Engineering CPI Technology Ltd Norgren Ireland Ltd Pilz Ireland WrenTech Ltd Tyco Valves & Controls Ireland Ltd

Medical Device Manufacture B.Braun Medical Croom Precision Medical

Membrane Filtration Systems microfiltration

Axium Process Fisher Scientific nanofiltration

Axium Process Fisher Scientific ultrafiltration

Axium Process Fisher Scientific 48


Meters CPI Technology Ltd Fisher Scientific Manotherm Ltd Petrochem Pipeline Supply Ltd

Microscopes Fisher Scientific Ocon Chemicals Ltd SciChem - Cork SciChem - Dublin

Milling CPI Technology Ltd Flexachem Manufacturing Ltd SciChem - Cork SciChem - Dublin WrenTech Ltd

Mixers CPI Technology Ltd Fisher Scientific Flexachem Manufacturing Ltd SciChem - Cork SciChem - Dublin Tyco Valves & Controls Ireland Ltd WrenTech Ltd

Noise/Odour Control

Millmount Healthcare NPP Group Ltd PrimePac Ltd Quitmann O’Neill Packaging Ltd Smurfit Kappa Ireland Weber Labelling & Coding

B.Braun Medical Flexachem Manufacturing Ltd Medisize Ireland Ltd Tyco Valves & Controls Ireland Ltd

Packaging/Design Anecto Catalent Pharma Solutions Chesapeake Complas Packaging Ltd Industrial Packaging Ltd Interpac Measom Freer

Plastic Cores / Tubes Fisher Scientific Flexachem Manufacturing Ltd Smurfit Kappa Ireland

Packaging/Machinery Chesapeake Goliath Packaging Systems Ltd Interpac Millmount Healthcare NPP Group Ltd Quitmann O’Neill Packaging Ltd Weber Labelling & Coding WrenTech Ltd

Pallets Complas Packaging Ltd Goliath Packaging Systems Ltd Henley Forklift Group Ltd Interpac Quitmann O’Neill Packaging Ltd Smurfit Kappa Ireland WrenTech Ltd

Pharmaceutical Fabrication Axium Process Catalent Pharma Solutions Cross Technical Solutions ProSys Containment and Sampling Technology Tyco Valves & Controls Ireland Ltd

Enva Ireland Ltd

OEM Manufacturing

WrenTech Ltd

Pipes/Cores CPI Technology Ltd Petrochem Pipeline Supply Ltd Smurfit Kappa Ireland

Plastic Containers Chesapeake CPI Technology Ltd Fisher Scientific Industrial Packaging Ltd Measom Freer Medisize Ireland Ltd Ocon Chemicals Ltd PrimePac Ltd SciChem - Cork SciChem - Dublin 49

Pneumatics Airpower Bosch Rexroth Ltd P.J. Boner & Co. Ltd Fisher Scientific Flexachem Manufacturing Ltd Norgren Ireland Ltd

Pollution Control Callaghan Engineering Enva Ireland Ltd

Powder Handling Carbon Goup CPI Technology Ltd Flexachem Manufacturing Ltd Goliath Packaging Systems Ltd ProSys Containment and Sampling Technology Quitmann O’Neill Packaging Ltd Tyco Valves & Controls Ireland Ltd WrenTech Ltd

Pressure Measurements/ Switches/Vessels Airpower Axium Process P.J. Boner & Co. Ltd BS&B Safety Systems Ltd Flexachem Manufacturing Ltd Manotherm Ltd Norgren Ireland Ltd Petrochem Pipeline Supply Ltd

Pressure Vessels Airpower CPI Technology Ltd Flexachem Manufacturing Ltd Graham Hart (Process Technology) Ltd H.R. Holfeld (Engineering) Ltd

G e n e r a l S u pp l i e r s

Irish PharmaChem 2011


Irish PharmaChem 2011 G e n e r a l S u pp l i e r s

Petrochem Pipeline Supply Ltd ProSys Containment and Sampling Technology Tyco Valves & Controls Ireland Ltd WrenTech Ltd

Project Management Axium Process Callaghan Engineering Glanbia Estates Goliath Packaging Systems Ltd Pilz Ireland

Pressure Relief Airpower CPI Technology Ltd Flexachem Manufacturing Ltd Manotherm Ltd Norgren Ireland Ltd Petrochem Pipeline Supply Ltd Pilz Ireland Tyco Valves & Controls Ireland Ltd

Print Packaging Contego Packaging Group Healthcare (Formerly Nampak)

Process Control Axium Process P.J. Boner & Co. Ltd Callaghan Engineering H.R. Holfeld (Engineering) Ltd Manotherm Ltd Norgren Ireland Ltd Petrochem Pipeline Supply Ltd Pilz Ireland Sartorius Mechatronics Ltd Tyco Valves & Controls Ireland Ltd Weber Labelling & Coding

Process Design Callaghan Engineering Pilz Ireland Weber Labelling & Coding Tyco Valves & Controls Ireland Ltd

Process & Mechanical Engineering Contractors Axium Process Pilz Ireland Tyco Valves & Controls Ireland Ltd

Protective Clothing/ Apparatus Fisher Scientific

Pumps CPI Technology Ltd Fisher Scientific Flexachem Manufacturing Ltd H.R. Holfeld (Engineering) Ltd ProSys Containment and Sampling Technology Waters Chromatography Ireland

Quality & Compliance Ann McGee Consulting Ltd

Lancaster Laboratories Matheson Ormsby Prentice

Refrigeration/Freezing Cross Technical Solutions CRS Mobile Cold Storage Dalkia Dawsonrentals Irl Ltd Ocon Chemicals Ltd SciChem - Cork SciChem - Dublin

Renewable Energy Dalkia Sustainable Energy Authority of Ireland

Robotics ABB Ltd

Sanitary Tubing CPI Technology Ltd Flexachem Manufacturing Ltd Petrochem Pipeline Supply Ltd

R&D Axium Process Lancaster Laboratories Medisize Ireland Ltd PPD Inc. Quintiles Ireland Ltd SciChem - Cork SciChem - Dublin Topchem Pharmaceuticals Ltd Tyco Valves & Controls Ireland Ltd WrenTech Ltd

Reactors CPI Technology Ltd Flexachem Manufacturing Ltd Tyco Valves & Controls Ireland Ltd

Recruitment Berkley Group Brightwater CPL Science & Engineering ICDS Recruitment Consultants 50

SCADA/DCS/MIS P.J. Boner & Co. Ltd

Scrubbers Graham Hart (Process Technology) Ltd

Screens Flexachem Manufacturing Ltd

Seals & Gaskets Flexachem Manufacturing Ltd Quitmann O’Neill Packaging Ltd Tyco Valves & Controls Ireland Ltd


Sieving Fisher Scientific Ocon Chemicals Ltd WrenTech Ltd

Software Sartorius Mechatronics Ltd Weber Labelling & Coding

Solvent Recovery/ Services Associated Chemicals Ltd CPI Technology Ltd Enva Ireland Ltd Indaver Ireland Soltec (Ireland) Ltd

Stainless Steel/ Fittings/Products CPI Technology Ltd Festo Ltd Fisher Scientific Interpac Petrochem Pipeline Supply Ltd Quitmann O’Neill Packaging Ltd Tyco Valves & Controls Ireland Ltd

Steam Equipment CPI Technology Ltd Flexachem Manufacturing Ltd Manotherm Ltd Petrochem Pipeline Supply Ltd Tyco Valves & Controls Ireland Ltd

Storage/Bunding Carbon Goup CRS Mobile Cold Storage Dawsonrentals Irl Ltd Enva Ireland Ltd Interpac SciChem - Cork SciChem - Dublin WrenTech Ltd

Supply Chain Management Catalent Pharma Solutions C+G Logistics Group Chesapeake GS1 Ireland KWE (Ireland) Ltd Movianto Ireland

Tableting Equipment Flexachem Manufacturing Ltd Goliath Packaging Systems Ltd ProSys Containment and Sampling Technology WrenTech Ltd

Tools Airpower

Transport & Logistics C+G Logistics Group Celtic Forwarding Ltd Chemsource Logistics Hazchem Training Ltd Irish Lift Trucks KWE (Ireland) Ltd Movianto Ireland Quitmann O’Neill Packaging Ltd

Tube Sets/Disposables Tanks Axium Process Celtic Forwarding Ltd Complas Packaging Ltd CPI Technology Ltd Quitmann O’Neill Packaging Ltd WrenTech Ltd

Temperature Control P.J. Boner & Co. Ltd Cross Technical Solutions Dawsonrentals Irl Ltd Flexachem Manufacturing Ltd Manotherm Ltd Movianto Ireland Petrochem Pipeline Supply Ltd Tyco Valves & Controls Ireland Ltd

Testing Services Anecto P.J. Boner & Co. Ltd CPI Technology Ltd Cross Technical Solutions Irish National Accreditation Board Lancaster Laboratories PPD Inc. Waters Chromatography Ireland

Thermal Imaging/ Thermography Dalkia Manotherm Ltd 51

Fisher Scientific Micro Hydraulics Ltd/Micro Industries Ireland

Vacuum Systems Airpower CPI Technology Ltd Fisher Scientific Enva Ireland Ltd Flexachem Manufacturing Ltd Norgren Ireland Ltd WrenTech Ltd

Valves Airpower Axium Process BS&B Safety Systems Ltd CPI Technology Ltd Flexachem Manufacturing Ltd Manotherm Ltd Norgren Ireland Ltd Petrochem Pipeline Supply Ltd ProSys Containment and Sampling Technology Tyco Valves & Controls Ireland Ltd

Validation Ann McGee Consulting Ltd Callaghan Engineering Lancaster Laboratories Pilz Ireland PPD Inc.

G e n e r a l S u pp l i e r s

Irish PharmaChem 2011


Irish PharmaChem 2011 G e n e r a l S u pp l i e r s

Ventilation Callaghan Engineering Cross Technical Solutions

Washing Equipment Goliath Packaging Systems Ltd SciChem - Cork SciChem - Dublin WrenTech Ltd

Carbon Goup Enva Ireland Ltd Flexachem Manufacturing Ltd Goulding Chemicals Ltd Norgren Ireland Ltd Tyco Valves & Controls Ireland Ltd

Vision Systems Airpower Weber Labelling & Coding

Warehouse Management Celtic Forwarding Ltd Chemsource Logistics Complas Packaging Ltd C+G Logistics Group Goliath Packaging Systems Ltd Movianto Ireland

Waste Management/ Balers/Recycling Axium Process Enva Ireland Ltd Goliath Packaging Systems Ltd Interpac Ocon Chemicals Ltd Quitmann O’Neill Packaging Ltd

Water Treatment ABB Ltd Associated Chemicals Ltd Axium Process

Notes

52

Weighing P.J. Boner & Co. Ltd Fisher Scientific Goliath Packaging Systems Ltd Sartorius Mechatronics Ltd SciChem - Cork SciChem - Dublin Weber Labelling & Coding WrenTech Ltd


Irish PharmaChem 2011

A

Associated Chemicals Ltd

Abb Ltd

Address: Belgard Road, Tallaght, Dublin 24. Tel: (01) 405 7300 Fax: (01) 405 7327 Email: marketing@ie.abb.com Web: www.abb.com Business: Lifescience solutions.

Airpower

Address: Unit 12F, Six Cross Roads, Business Park, Waterford. Tel: (051) 373 937 Fax: (051) 820 903 Email: Stephen@airpower.ie Web: www.airpower.ie Business: Pneumatic Components. Contact: Marketing Manager: Stephen Murphy.

Anecto

Address: Tel: Fax: Email: Web: Business:

Mervue Business Park, Co. Galway. (091) 757 404 (091) 757 387 sales@anecto.com www.anecto.com Dangerous goods packaging testing laboratory.

Ann McGee Consulting Ltd

Address: Tel: Fax: Email: Web: Business:

Company Listings

Company Listings

Unit 63, Grange Close, Baldoyle Industrial Estate, Baldoyle, Dublin 13. (01) 832 5948 (01) 832 5949 info@annmcgee.com www.annmcgee.com Pharmaceutical Quality, Compliance and Training Specialists.

Address: Tel: Fax: Email: Business: Contact:

16D Euro Business Park, Little Island, Co. Cork (021) 435 1014 (021) 435 1015 info@acl.ie Chemical Supplies Managing Director: Sylvester Cotter.

Berkley Group

Address: Unit B7, Centre Point Business Park, Oak Road, Dublin 12. Tel: (01) 460 7070 Fax: (01) 461 0771 Email: automationsales@atc.ie Web: www.atc.ie

Address: Tel: Email: Web: Contact:

Axium Process

Betco Marketing Ltd

ATC Automation ltd

Address: Hendy Industrial Estate, Hendy, Swansea, SA4 0XP. Tel: (0044) 1792 883882 Fax: (0044) 1792 886049 Email: info@axiumprocess.com Web: www.axiumprocess.com

Address: Tel: Fax: Email: Web: Contact:

Dublin: 509 The Capel Building, Mary’s Abbey, Dublin 7. Cork: Mill House, Carrigrohane, Co. Cork. (01) 872 4666 (021) 428 9600 pharma@berkley.ie www.berkley.ie Joanna Houston Exham House, The Fingerpost, Douglas, Co. Cork. (021) 436 4999 (021) 436 5739 dhalpin@betco.ie www.betco.ie Managing Director: Diarmuid Halpin

B

B. Braun Medical Address: Tel: Fax: Email: Web: Business: Contact:

3 Naas Road Industrial Park, Dublin 12. (01) 709 1801 (01) 709 1889 bill.proctor@bbraun.com www.bbraun.com OEM manufacturing. Business Unit Manager: Bill Proctor

53

P.J. Boner & Co. Ltd Instrument & Weighing Specialists Address: Tel: Fax: Email: Web: Business: Contact:

35 Western Parkway Business Centre, Ballymount Drive, Ballymount, Dublin 12. (01) 450 5050 (01) 450 5183 info@pjboner.com www.pjboner.com Instrument & weighing specialists. Calibrations. Managing Director: Patrick Michael Boner


Irish PharmaChem 2011 Company Listings

Bosch Rexroth Ltd Address: Tel: Fax: Email: Web: Business: Contact:

Unit 6, Lismard Business Park, Timahoe Road, Portlaoise, Co Laois. (057) 867 8200 (057) 867 8201 info@boschrexroth.ie www.boschrexroth.ie Engineering Regional Sales Manager: John Doran

Brenntag Ireland

Address: Unit 405, Greenogue Business Park, Rathcoole, Dublin 24. Tel: (01) 401 3500 Fax: (01) 405 3501 Email: dublin.sales@brenntag.ie Web: www.brenntag.ie Contact: General Manager: Bill Maher

Brightwater

Address: 36 Merrion Square, Dublin 2. Tel: (01) 662 1000 Fax: (01) 662 3900 Email: e.moloney@brightwater.ie Web: www.brightwater.ie Contact: Eileen Moloney

BS&B Safety Systems Ltd Address: Tel: Fax: Email: Web: Business: Contact:

Raheen Business Park, Raheen, Co. Limerick. (061) 484 700 Emergency Delivery: 086 241 0615 Direct Line: 086 838 5556 (061) 352 240 sales@bsb.ie www.bsb.ie Pressure relief devices. Sales Manager: Patrick Murphy

C

Catalent Pharma Solutions

Callaghan Engineering Address: Tel: Fax: Tel: Fax: Email: Web: Business:

Dublin: Wentworth House, 19/20 Hogan Place, Lower Grand Canal St, Dublin 2. (01) 661 4420 (01) 661 4424 Cork: Suite 257, Building 1000, Units 1201& 1202, City Gate, Mahon, Cork. (021) 240 9099 (021) 240 9009 mail@calleng.ie www.calleng.ie Multi-discipline consulting engineering and project manage- ment company.

Camida Ltd

Address: Tel: Fax: Email: Web: Contact:

Tower House, New Quay, Clonmel, Co. Tipperary. (052) 612 5455 (052) 612 5466 info@camida.com www.camida.com Company Secretary: Deirdre McGrath

Carbon Group

Address: Factory Cross, Ringaskiddy, Co. Cork. Tel: +353 (0)21 437 8988 UK Local Lo-Call: (0044) 8708 504 831 Fax: +353 (0)21 437 8950 Email: carol.deegan@carbon.ie sales@carbon.ie Web: www.carbon.ie Business: Pharmachemicals. Contact: Area Sales Manager: Carol Deegan

54

Address: Unit 26, Cherry Orchard Industrial Estate, Dublin 10. Tel: (01) 620 0600 Fax: (01) 626 2815 Email: diarmuid.wilson@catalent.com Web: www.catalent.com Business: Contract manufacturing capabilities as well as packaging and printed components to the pharmaceutical industry. Contact: Director of Business Development: Diarmuid Wilson

Celtic Forwarding Ltd

Address: Dublin: Celtic House, 30 Marlborough Street, Dublin 1. Waterford: Belview Port, Slieverue, Co. Waterford. Tel: (01) 865 6000 (051) 851 821 Fax: (01) 874 6745 (051) 851 823 Email: info@celticfwd.ie Web: www.celticfwd.ie Business: Shipping. Contact: Director: Finbarr Cleary Sales Manager: Gerald Kiernan DGSA Tank Division Manager: Patty deCourcey

C + G Logistics Group

Address: Westpoint Business Park, Navan Road, Mulhuddart, Dublin 15. Tel: (01) 820 8455 Fax: (01) 820 8457 Email: info@cglogistics.ie Web: www.cglogistics.ie Contact: General Manager/ Director : Patrick Wogan Business Development Manager: Cormac Sarsfield


Chemco Ireland Ltd. Address: Tel: Fax: Email: Web: Business: Contact:

Unit 2, Stadium Business Park, Ballycoolin Road, Cappagh, Dublin 11. (01) 829 3600 (01) 885 5029 sales@chemco.ie www.chemco.ie Chemical Distribution. Sales Director: Peter Fitzgerald

Chemtek Sales Ltd Address: Tel: Fax: Email: Web:

Estuary House, New Street, Malahide, Co. Dublin. (01) 845 3766/63 (01) 845 3172 sales@chemtek.ie www.chemtek.ie

Chesapeake

Address: Enterprise Way, Hightown Industrial Estate, Newtownabbey, Belfast, BT36 4EW. Tel: (0044) 2890 804 000 Fax: (0044) 2890 804 301 Email: sales.pharma@chesapeakecorp.com Web: www.chesapeake.com/pharma Business: Pharmaceutical and healthcare packaging (cartons, labels, leaflets and more).

Complas Packaging Ltd Address: Tel: Fax: Email: Web:

Naas Industrial Estate, Dublin Road, Naas, Co. Kildare. (045) 874 088/9 (045) 874 090 sales@complas.ie www.complas.ie

Unit 2, Stadium Business Park, Ballycoolin Road, Cappagh, Dublin 11. (01) 882 9117 (01) 885 5029 info@chemsource.ie www.chemsource.ie Chemical Distributors. Director: John Farrell

Chemsource Logistics Address: Tel: Fax: Email: Web: Business: Contact:

Unit 2, Stadium Business Park, Ballycoolin Road, Cappagh, Dublin 11. (01) 885 3977 (01) 885 3978 info@chemsource.ie www.chemsource.ie Warehousing, transport & logistics Director: Sandy McConnachie

Address: Unit 629 IDA Industrial Park, Northern Extension, Old Kilmeaden Road, Waterford. Tel: (051) 595 300 Fax: (051) 595 309 Email: sales.ireland@contegopackaging.com Web: www.contegopackaging.com Business: Carton & leaflet suppliers to the pharmaceutical industry. Contact: Business Development Manager: Maria Moran

Corcoran Chemicals Ltd

Chemsource Industrial Division Address: Tel: Fax: Email: Web: Business: Contact:

Contego Packaging Group Healthcare (Formerly Nampak Healthcare)

Clip Ltd Ireland Address: Tel: Email: Web: Business: Contact:

First Floor, Cillin Hill, Dublin Road, Kilkenny. (086) 828 3620 paul.smith@clipdisplay.ie www.clipdisplay.ie Exhibition and display equipment manufacture and service. Irish Sales Manager: Paul Smith

Address: Kingsbridge House, 17-22 Parkgate Street, Dublin 8. Tel: (01) 633 0400 Fax: (01) 679 3521 Email: info@corcoranchemicals.com Web: www.corcoranchemicals.com Business: Distribution. Contact: Sales Department

CPI Technology Ltd

Address: Unit 5 Link Road Business Park, Ballincollig, Co. Cork. Tel: (021) 487 4142 Fax: (021) 487 8764 Email: info@cpitechnology.com Web: www.cpitechnology.com Business: Providers of Process Equipment. Contact: Managing Director: Adrian Giltinan

55

Company Listings

Irish PharmaChem 2011


Irish PharmaChem 2011 Company Listings

CPL Science & Engineering

Address: 83 Merrion Square South, Dublin 2. Tel: (01) 614 6000 / (01) 614 6132 Fax: (01) 614 7274 Email: Judith.Moffett@cpl.ie Web: www.cpl.ie Business: Recruitment. Contact: Science & Engineering Manager: Judith Moffett

Croom Precision Medical

Address: Enterprise Centre, Croom, Co. Limerick. Tel: (061) 397 744 Fax: (061) 397 639 Email: info@croomprecision.ie Web: www.croomprecision.com Business: Medical device manufacture. Contact: Managing Director: Patrick Byrnes

Cross Technical Solutions Address: Tel: Fax: Email: Web: Business: Contact:

Unit 26, Second Avenue, Cookstown Industrial Estate, Cookstown, Tallaght, Dublin 24. (01) 405 6777 (01) 413 6932 jmcgrath@cross technicalsolutions.ie www.crosstechnical solutions.ie Refrigeration. Technical Director: Jonathan McGrath General Manager: Jason Keating

CRS Mobile Cold Storage

Address: Tel: Fax: Email: Web:

Arctic House, Carnisle, Kildalkey, Co. Meath (046) 943 5000 (046) 943 5068 enquiry@crs.ie www.crs.ie

Business: Contact:

Cold storage, pharmaceutical storage, bespoke refrigeration John Tyrell

D

Address: Tel: Fax: Email: Web:

PO Box 3000, Johnstown Castle Estate, Co. Wexford. (053) 916 0600 (053) 916 0699 info@epa.ie www.epa.ie

Eurolec Instrumentation Ltd

Dalkia Address: Tel: Fax: Email: Web: Contact:

Environmental Protection Agency

145 Lakeview Drive, Airside Business Park, Swords, Co. Dublin. (01) 870 1200 (01) 870 1201 info@dalkia.ie www.dalkia.ie Managing Director: Pat Gilroy Industrial Director Pharmaceutical & Health: Fergus Elebert

Address: Technology House, Cluan Enda, Dundalk, Co. Louth. Tel: (042) 933 3423 Fax: (042) 933 1758 Email: eurolec@esatclear.ie Web: www.eurolec-instruments.com Business: Electronic instrumentation. Contact: Sales/Marketing Executive: Chris Mears

F Dawsonrentals Irl. Ltd

Address: Unit 20 Tougher Business Park, Newhall, Naas, Co. Kildare. Tel: (045) 448 810 Fax: (045) 448 811 Email: aidanmccauley@eircom.net Web: www.dawsonrentalsireland.com Business: Temperature Control Solutions. Contact: Director: Aidan McCauley

E Enva Ireland Ltd

Address: Tel: Fax: Email: Web:

Raffeen Industrial Estate, Ringaskiddy, Co. Cork. (021) 438 7200 (021) 438 7299 cork@enva.ie www.enva.ie 56

Festo Ltd

Address: Unit 5, Sandyford Park, Sandyford Industrial Estate, Dublin 18. Tel: (01) 295 4955 Fax: (01) 295 5680 Email: sales_ie@festo.com Web: www.festo.com/ie Business: Automation company specialising in factory and process automation. Contact: Sales Manager: Diarmaid Cowhie


H Hazchem Training Ltd Fisher Scientific

Address: Suite 4, Plaza 212, Blanchardstown Corporate Park 2, Ballycoolin, Dublin 15. Tel: (01) 885 5854 Fax: (01) 899 1855 Email: fsie.sales@thermofisher.com Web: www.ie.fishersci.com Business: Laboratory supplies. Contact: Marketing Manager: Gerry Fitzmaurice

Flexachem Manufacturing Ltd Address: Tel: Fax: Email: Web: Business: Contact:

Donnybrook Commercial Centre, Douglas, Co. Cork. (021) 461 7200 (021) 489 1297 sales@flexachem.com www.flexachem.com Manufacturer/ Distributor. Commercial Director: Agnes Mullins

G

Glanbia Estates

Address: Glanbia House, Ring Road, Co. Kilkenny. Tel: +353 (0) 87 256 4339 Email: gmullally@glanbia.com Web: www.kilmeadenfields.com Business: Property Business Unit of Glanbia PLC. Contact: CEO: Ger Mullally

Goliath Packaging Systems Ltd

Address: Beechwood, Nenagh, Co. Tipperary. Tel: (067) 37893 Fax: (067) 34794 Email: info@goliath.ie Web: www.goliath.ie Business: Supply & installation of packaging equipment and materials handling systems. Contact: Director: George O’Leary

Goulding Chemicals Ltd

Address: Centre Park Road, Marina, Cork City. Tel: (021) 491 1611 Fax: (021) 491 1660 Email: pollockm@gouldings.ie Web: www.gouldings.ie Business: Chemical distributor.

Graham Hart (Process Technology) Ltd

Address: Friars Ind. Estate, Bradford Road, Idle, Bradford, BD10 8SW, UK. Tel: (0044) 1274 617021 Fax: (0044) 1274 618614 Email: sales@graham-hart.com Web: www.graham-hart.com Contact: Sales Director: Stephen Hart

GS1 Ireland

Address: The Nutley Building, Merrion Road, Dublin 4. Tel: (01) 208 0660 Fax: (01) 208 0670 Email: info@gs1ie.org Web: www.gs1ie.org Contact: Member Support Services: Karen Murphy 57

Address: G10, Maynooth Business Campus, Maynooth, Co. Kildare. Tel: (01) 629 1800 Fax: (01) 629 1822 Email: info@hazchem.ie Web: www.hazchem.ie Contact: Director: Michelle Cleere

Henley Forklift Group Ltd Address: Tel: Fax: Email: Web: Business: Contact:

Henley Industrial Park, Killeen Road, Dublin 10. (01) 620 9200 (01) 626 5406 fwilson@henley.ie phammett@henley.ie www.henley.ie Forklifts & Warehousing Equipment. Specialists in flameproof forklift trucks. Director: Mark Kenny Director: Brian O’Connell

HOCHTIEF Facility Management Address: Tel: Fax: Email: Web:

Ireland: HOCHTIEF Facility Management Ireland Ltd., Landscape House, Landscape Road, Churchtown, Dublin 14. UK: HOCHTIEF Facility Management UK Ltd, HOCHTIEF House, 2 Ibis Court, Centre Park, WarringtonWA1 1RL (01) 215 7000 +44 1925 404 500 (01) 215 7070 +44 1925 404 598 www.hochtief-fm.ie

Company Listings

Irish PharmaChem 2011


Irish PharmaChem 2011 Company Listings

Business: Contact:

Facilities Management. Region Operations Manager: Ray Casey

H.R. Holfeld (Engineering) Ltd Address: Tel: Fax: Email: Web: Type of Business: Contact:

2-4 Merville Road, Stillorgan, Co. Dublin. (01) 288 7361 (01) 288 7380 pumps@holfeld.ie www.holfeld.ie Process Pump Supplier. Business Development & Key Accounts: Emmet Connelly

HRB Clinical Research Facility

IDA Ireland

Address: Wilton Park House, Wilton Place, Dublin 2. Tel: (01) 603 4000 Email: idaireland@ida.ie Web: www.idaireland.com Business: Investment promotion agency. Contact: Global Head of Life Sciences: David Shanahan

Indaver Ireland

Address: 4 Haddington Terrace, Dun Laoghaire, Co. Dublin. Tel: (01) 280 4534 Fax: (01) 280 7865 Email: info@indaver.ie Web: www.indaver.ie Business: Hazardous & non- hazardous waste disposal and recovery ensuring full compliance.

Business:

Packaging.

Contact:

Managing Director: Ian Sutton

Invest Northern Ireland

Address: Bedford Square, Bedford Street, Belfast, BT2 7ES. Tel: (048) 9069 8601 Fax: (048) 9043 6536 Email: patricia.oneill@investni.com Web: www.investni.com Business: Economic development agency. Contact: Patricia O’Neill

Irish Exporters Association Life Sciences Ireland

Address: 28 Merrion Square, Dublin 2. Tel: (01) 661 2182 Fax: (01) 661 2315 Email: raulmolina@ irishexporters.org Web: www.irishexporters.org Business: Life Sciences Ireland is Industry Grouping within the Irish Exporters Association.

Address:

NUI Galway, Geata an Eolais, University Road, Galway. Tel: (091) 495 892 Fax: (091) 526 027 Email: lisa.daly@nuigalway.ie Web: www.crfg.ie Business: Clinical Research Contact: Programme Manager: Lisa Daly

I ICDS Recruitment Consultants

Address: 24 Upper Fitzwilliam Street, Dublin 2. Tel: (01) 632 1200 Fax: (01) 676 2079 Email: info@icds.ie Web: www.icds.ie Business: Recruitment consultants. Contact: Recruitment Director: Anthony McLoughlin

Industrial Packaging Ltd

Address: Killarney Road, Bray, Co. Wicklow. Tel: (01) 286 4010 Email: mail@industrialpackaging.ie Web: www.industrialpackaging.ie Business: Manufacturer of fibre drums. Contact: Managing Director: Norman Lee

Interpac Address: Tel: Email: Web:

67E Heather Road, Sandyford Industrial Estate, Dublin 18. (01) 294 0600 ian@interpac.ie www.interpac.ie 58

Irish Lift Trucks Address: Clonlara Avenue, Tel: Fax: Email: Web: Business: Contact:

Baldonnell Business Park, Baldonnell, Dublin 22. (01) 403 4100 (01) 403 4183 info@irishlifttrucks.ie www.irishlifttrucks.ie Materials Handling Equipment / Hyster Forklifts / Lancer Sideloaders General Manager: Conal McCourt

Irish National Accreditation Board, The Address:

Wilton Park House, Wilton Place, Dublin 2.


Tel: Fax: Email: Web: Business: Contact:

(01) 607 3003 (01) 607 3109 inab@inab.ie www.inab.ie Provides accreditation of laboratories, certification & inspection bodies. Information Officer: Orla Doyle

J

Java Clinical Research Ltd Address: Tel: Fax: Email: Web: Business: Contact:

Fitzwilliam Buiness Centre, 26 Upper Pembroke St, Dublin 2. 01 637 3903 01 637 3907 info@javacr.com www.javacr.com Clinical Research Managing Director: Ruth Nallen

K

KWE (Ireland) Ltd

Address: Dublin: Unit 4 Horizon Logistics Park, New Naul Rd, Harristown, Swords, Co. Dublin. Cork: Unit 4&5, South Ring West Business Pk, Tramore Road, Co. Cork. Tel: (01) 823 9600 (021) 497 5722 Fax: (01) 836 1111 (021) 497 5727 Email: kwedub@ea.kwe.com kweork@ea.kwe.com Web: www.kwe.com Contact: Sales Manager: Karl O’Reilly

L

Manotherm Ltd

Lancaster Laboratories

Address: IDA Business Park, Clogherane, Dungarvan, Co. Waterford Tel: (058) 48 300 Fax: (058) 42 855 Email: info@lancasterlabs.com Web: www.lancasterlabspharm.com Business: Contract Analytical Services Contact: Business Development Director: Mark Glass

Lennox Laboratory Supplies Ltd

Address: Tel: Fax: Email: Web: Business:

John F. Kennedy Drive, Naas Road, Dublin 12. (01) 455 2201 (01) 450 7906 sales@lennox.ie greg@lennox.ie www.lennox.ie Laboratory suppliers.

Lister Machine Tools Ltd

Address: PO Box 838, Bluebell Industrial Estate, Dublin 12. Tel: (01) 450 8866 Fax: (01) 450 9836 Email: sales@listermachinetools.com Web: www.listermachinetools.com Business: Sale of machine tools & associated equipment.

M MacLachlan & Donaldson

Address: 47 Merrion Square, Dublin 2. Tel: (01) 676 3465 Fax: (01) 661 2083   Email: mail@maclachlan.ie Web: www.maclachlan.ie Business: Intellectual Property Attorneys Contact: Dr. YvonneMcKeown 59

Address: 4 Walkinstown Road, Dublin 12. Tel: (01) 452 2355 Fax: (01) 451 6919 Email: info@manotherm.ie Web: www.manotherm.ie Business: Distributors of controls and instrumentation. Contact: Managing Director: R.C. Gilbert

Matheson Ormsby Prentice

Address: 70 Sir John Rogerson’s Quay, Dublin 2. Tel: (01) 232 2000 Fax: (01) 232 3333 Web: www.mop.ie Business: Law firm

Measom Freer

Address: 37-41 Chartwell Drive, Wigston, Leicester, LE18 2FL, UK. Tel: (0044) 1162 881588 Fax: (0044) 1162 813000 Email: sales@measomfreer.co.uk Web: www.measomfreer.co.uk Business: Manufacturer. Contact: Sales Director: Mark Freer

Medisize Ireland Ltd

Address: High Road, Letterkenny, Co. Donegal. Tel: (074) 918 8549 Email: info@medisize.com Web: www.medisize.com Business: Contract manufacturer of primary pharmaceutical packaging and medical and diagnostic devices. Contact: Business Development Manager: Marie Nelis

Company Listings

Irish PharmaChem 2011


Irish PharmaChem 2011 Company Listings

Micro Hydraulics Ltd/ Micro Industries Ireland

Address: Dublin: 2003 Orchard Avenue, Citywest Business Campus, Dublin 24. Tel: (01) 463 9100 Fax: (01) 410 5609 Cork: Unit 6/7 Cherrywood Business Park, Little Island, Co. Cork. Tel: (021) 451 0570 Fax: (021) 451 0572 Email: info@microhydraulics.ie Web: www.microhydraulics.ie Business: Sanitary hose, tube, sets/disposable. Contact: Sales Representative: Ralph Fitzsimons Sales Representative: Dave O’Donavan

Millmount Healthcare

Address: Block 7, CityNorth Business Campus, Stamullen, Co. Meath. Tel: (01) 841 8300 Fax: (01) 841 8039 Email: info@millmount.com Web: www.millmounthealthcare.ie Business: Full-service contract packaging service provider for the pharmaceutical industry. Fully licensed for primary / secondary packaging, warehousing and EU batch releases. Contact: Managing Director: Pascal Keogh

Movianto Ireland

Address: Pharmapark, Chapelizod, Dublin 20. Tel: (01) 630 5305 Fax: (01) 630 5400 Email: james.quinn@movianto.com Business: Movianto is a logistics and distribution service provider, specialising in the pharmaceutical, biotechnology and healthcare industries. Contact: Commerial Director: James Quinn

N

NPP Group Ltd Address: Tel: Email: Web: Business: Contact:

Unit 509, Mitchelstown Road, Northwest Business Park, Ballycoolin, Blanchardstown, Dublin 15. (01) 880 9299 sales@npp.ie bmcmahon@npp.ie www.npp.ie Flexible packaging suppliers & distributors. Sales Director: Eoin McDonagh

National Chemical Co. Ltd

Address: Tel: Fax: Email: Web: Business: Contact:

NCC House, 42 Lower Leeson St., Dublin 2. (01) 613 1400 (01) 634 0132 sales@ncc.ie www.ncc.ie Distributor. Sales Director: Christy Smith

Norgren Ireland Ltd Address: Tel: Fax: Email: Web: Business:

137 Slaney Close, Dublin Industrial Estate, Glasnevin, Dublin 11. (01) 830 0288 (01) 830 0082 dublin@norgren.com www.norgren.com Fluid and motion control. ‘Pneumatics’ automation components.

60

O Ocon Chemicals Ltd

Address: Unit 5, South Cork Industrial Estate, Vicars Road, Pouladuff, Co. Cork. Tel: (021) 431 8555 Fax: (021) 431 8560 Email: info@oconchemicals.com Web: www.oconchemicals.com Contact: Managing Director: Frank Mulcahy

O’Flynn Medical Ltd

Address: Westend, Millstreet, Co. Cork. Tel: (029) 21 799 Fax: (029) 70 191 Email: info@oflynnmedical.com Web: www.oflynnmedical.com Business: Distributor of Scrubex “Automated Protective Clothing Distributor” Contact: Managing Director: Tadhg O’Flynn


P

P.K. Chemicals Ltd

Petrochem Pipeline Supply Ltd Address: Tel: Fax: Email: Web: Contact: Address: Tel: Fax: Email: Web: Contact: Business:

Cork: Unit 14, Euro Business Park, Little Island, Co. Cork. (021) 4351300 (021) 4351166 sales@petrochem.ie www.petrochem.ie Sales Manager: Dave Ahern Dublin: Europa House Dunboyne Business Park, Dunboyne, Co. Meath. (01) 802 6020 (01) 801 5860 noel@petrochem.ie www.petrochem.ie Noel Donnelly, Declan Murphy Supplier of Stainless Steel Pipes, Fittings, Flanges, Fasteners, Valves, Steam Products, Instrumentation and Controls to the Irish Pharmaceutical and Biotech markets.

Pilz Ireland Address: Tel: Fax: Email: Web: Business: Contact:

Cork Business & Technology Park, Model Farm Road, Co Cork. (021) 434 6535 (021) 480 4994 sales@pilz.ie www.pilz.ie Process and machinery saftey engineering services and training. Sales Manager: Andrew Donnelly MD: John McAuliffe

Address: Tel: Fax: Email: Business: Contact:

Unit 23, Sandyford Office Park, Blackthorn Avenue, Foxrock, Dublin 18. (01) 295 6977 (01) 295 8338 debbie@pkchemicals.com Chemical Distributor. Purchasing and Sales Manager: Sarah Murphy

PPD, Inc.

Address: Building C, Athlone Business & Technology Park, Garrycastle, Athlone, Co. Westmeath Tel: (0906) 460 300 Fax: (0906) 460 301 Email: susan.neenan@ppdi.com Web: www.ppdi.com Business: Contract Research Organisation Contact: Director, GMP Labs, Europe: Susan Neenan

ProSys Containment And Sampling technology Address: Tel: Fax: Email: Web: Business: Contact:

Rosehill Business Centre, Ballinacurra, Midleton, Co. Cork. (021) 461 3890 (021) 461 3891 mmcl@prosys.ie www.prosys.ie Design and maunfacture of sampling and isolators for the pharmaceutical and chemical industries. Managing Director: Michael McLoughlin

Q

PrimePac Ltd

Address: Unit 2, Caulside Drive, Newpark Industrial Estate, Antrim, BT41 2DU. Tel: (0044) 2894 428 188 Fax: (0044) 2894 428 177 Email: sales@primepacltd.com Web: www.primepacltd.com Business: Manufacturer & supplier of plastic containers. Contact: Director: John McGahon

Quintiles Ireland Ltd

Address: Tel: Fax: Web: Business: Contact:

Eastpoint Business Park, Fairview, Dublin 3. (01) 819 5100 (01) 809 9500 www.quintiles.com Clinical Research and Development Managing Director: John Kiernan

Quitmann O’Neill Packaging Ltd

Address: St. Brendan’s Road, Portumna, Co. Galway. Tel: (090) 974 1148/9 Fax: (090) 974 1459 Email: sales@quitmannoneill.com Web: www.qonpack.com Business: Packaging stockist & distributors. Contact: General Manager: David O’Neill 61

Company Listings

Irish PharmaChem 2011


Irish PharmaChem 2011 Company Listings

S Sartorius Mechatronics UK Ltd Address: Tel: Fax: Email: Web: Business: Contact:

Unit 41, The Business Centre, Stadium Business Park, Ballycoolin Road, Dublin 11. (01) 808 9050 (01) 808 9388 info.ireland@ sartorius.com www.sartorius.ie Laboratory & process technology provider. Sales & service of laboratory & process weighing equipment. Nick Parsons

SciChem - Cork

Address: Tel: Fax: Email: Web: Business: Contact:

Unit 14, Barryscourt Business Park, Carrigtwohill, Co. Cork. (021) 488 2388 (021) 488 2389 cork@scichem.com www.scichem.com Laboratory Suppliers. Branch Manager: John Molloy

SciChem - Dublin Address: Tel: Fax: Email: Web: Business: Contact:

Greenhills Industrial Estate, Walkinstown, Dublin 12. (01) 450 4077 (01) 450 4328 dublin@scichem.com www.scichem.com Laboratory Suppliers. Branch Manager: Seamus Amond

Science Foundation Ireland (SFI) Address: Tel: Fax: Email: Web:

Wilton Park House, Wilton Place, Dublin 2. (01) 607 3200 (01) 607 3201 info@sfi.ie www.sfi.ie

Business: Contact:

Government funding agency for research. Head of Industry - Research Development: Dr. Paul Dodd

Smurfit Kappa Ireland

Address: Tel: Fax: Email: Web: Business: Contact:

Ballymount Road, Walkinstown, Dublin 12. (01) 409 0000 (01) 456 4506 info@smurfitkappa.ie www.smurfitkappa.ie www.skpackaging.ie Packaging. Marketing Manager: Mark Munnelly

T

TopChem Pharmaceuticals Ltd

Address: Ballymote Business Park, Carrownanty, Ballymote, Co. Sligo. Tel: (071) 918 9685 Fax: (071) 919 7864 Email: donal@topchempharma.com Web: www.topchempharma.com Business: Development and manufacture of pharmaceutical active ingredients. Contact: Managing Director: Donal Coveney

Toyota Material Handling Ireland Ltd

Soltec (Ireland) Ltd

Address: Tel: Email: Web: Business: Contact:

Zone A, Mullingar Business Park, Mullingar, Co. Westmeath. (044) 933 5133 info@soltec.ie www.soltec.ie Soltec is Ireland’s only commercially operated solvent recycling plant. Solid hazardous waste collections also provided. Business Development Manager: Michael Corcoran

Sustainable Energy Authority of Ireland Address: Tel: Fax: Email: Web: Business:

Glasnevin, Dublin 9. (01) 836 9080 (01) 837 2848 info@sei.ie www.sei.ie Energy advice & information. 62

Address: Tel: Fax: Business: Contact:

Killeen Road, Dublin 12. (01) 419 0321 (01) 419 0325 Forklift and Warehouse Supplies. Sales Manager: Robert O’ Reilly

Tyco Valves & Controls Ireland Limited

Address: Victoria House, Beaumont Avenue, Churchtown, Dublin 14. Tel: (01) 295 1101 Email: tkilbane@tyco-valves.com Web: www.tycoflowcontrol-eu.com Business: Industrial valves & controls. Contact: General Manager: Tony Kilbane


U

Univar Ltd

Address: 536 Grants Crescent, Greenogue Business Park, Rathcoole, Co. Dublin. Tel: (01) 401 9800 Fax: (01) 401 9142 Email: pharma.sales@ univareurope.com Web: www.univareurope.com Business: Ingredients pharma industry including API’s, excipients, process chems, solvents & intermediates. Contact: Account Manager: John McCluskey

W

Weber Labelling & Coding

Waters Chromatography Ireland Address: Tel: Fax: Email: Web: Business: Contact:

Unit 3.1 Woodford Business Park, Santry, Dublin 9. (01) 448 1500 (01) 448 1510 ireland@waters.com www.waters.com The company designs, manufactures, sells and services HPLC, UPLC, mass spectrometry instrument systems and support products, including chemistry consumables and post-warranty service plans. National Sales Manager: Davnet Donnelly

Notes

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Address: Kilcannon Ind. Est., Old Dublin Road, Enniscorthy, Co. Wexford. Tel: (053) 923 3778 Fax: (053) 923 3284 Email: sales@weberireland.com Web: www.weberireland.com Contact: Operations Manager: Patrick Hughes

WrenTech Ltd Address: Tel: Fax: Email: Web: Contact:

Eversley, Church Bay Road, Crosshaven, Co. Cork. (021) 483 2644 (021) 483 1363 smurray@wrentech.ie www.wrentech.ie Sales Administrator: Siobhan Murray

Company Listings

Irish PharmaChem 2011


I r i s h P h a r m a C h e m 2011

Useful References ACADEMY OF MEDICAL LABORATORY SCIENCE Tel: (01) 677 5602 E-mail: mail@amls.ie Web: www.amls.ie

ENTERPRISE IRELAND Tel: (01) 727 2000 E-mail: client.service@enterprise-ireland.com Web: www.enterprise-ireland.com

Advisory Council for Science, Technology & Innovation Tel: (01) 607 3162 E-mail: firstname.surname@forfas.ie Web: www.sciencecouncil.ie

ENVIRONMENTAL HEALTH OFFICERS’ ASSOCIATION Tel: (01) 276 1211 E-mail: info@ehoa.ie Web: www.ehoa.ie

AN BORD PLEANALA Tel: (01) 858 8100 LoCall: 1890 275 175 E-mail: bord@pleanala.ie Web: www.pleanala.ie CHAMBERS IRELAND Tel: (01) 400 4300 E-mail: info@chambers.ie Web: www.chambers.ie COMPANIES REGISTRATION OFFICE Tel: (01) 804 5200 LoCall: 1890 220 226 E-mail: info@cro.ie Web: www.cro.ie UCD SCHOOL OF CHEMICAL & BIOPROCESS ENGINEERING Tel: (01) 716 1825 E-mail: chemical.eng@ucd.ie Web: www.ucd.ie/chembioeng DEPT. OF JOBS, ENTERPRISE & INNOVATION Tel: (01) 631 2121 LoCall: 1890 220 222 E-mail: info@djei.ie Web: www.djei.ie DEPT. OF THE ENVIRONMENT, COMMUNITY & LOCAL GOVERNMENT Tel: (01) 888 2000 LoCall: 1890 20 20 21 E-mail: press-office@environ.ie Web: www.environ.ie ELECTRICITY SUPPLY BOARD Tel: 1850 372 372 E-mail: esbnetworks@esb.ie Web: www.esb.ie

ENVIRONMENTAL PROTECTION AGENCY Tel: (053) 916 0600 LoCall: 1890 335 599 E-mail: info@epa.ie Web: www.epa.ie

INSTITUTE OF CHEMISTRY OF IRELAND E-mail: info@instituteofchemistry.org Web: www.instituteofchemistry.org

IRISH PATENTS OFFICE Tel: (056) 772 0111 E-mail: patlib@patentsoffice.ie Web: www.patentsoffice.ie

INTERNATIONAL SOCIETY FOR PHARMACEUTICAL ENGINERING (ISPE) Tel: +32 2 743 4422 E-mail: ispe@associationhq.org Web: www. ispe.org

IRISH PHARMACY UNION Tel: (01) 493 6401 E-mail: firstname.surname@ipu.ie Web: www.ipu.ie

IRISH BIOINDUSTRY ASSOCIATION Tel: (01) 605 1584 E-mail: firstname.surname@ibec.ie Web: www.ibec.ie/ibia IRISH BUSINESS & EMPLOYERS CONFEDERATION (IBEC) Tel: (01) 605 1500 E-mail: info@ibec.ie Web: www.ibec.ie

BIOTECHNOLOGY IRELAND Tel: (01) 727 2692 E-mail: editor@biotechnologyireland.com www.biotechnologyireland.com

IRISH CLEANROOM SOCIETY Tel: (091) 790693 E-mail: info@cleanrooms-ireland.ie Web: www.cleanrooms-ireland.ie

FAS - TRAINING & EMPLOYMENT AGENCY Tel: (01) 607 0500 E-mail: info@fas.ie Web: www.fas.ie FORFAS Tel: (01) 607 3000 E-mail: firstname.surname@forfas.ie Web: www.forfas.ie

IRISH COSMETICS, DETERGENT & ALLIED PRODUCTS ASSOCIATION Tel: (01) 605 1671 E-mail: siobhan.murphy@ibec.ie Web: www.icda.ie

HEALTH AND SAFETY AUTHORITY Tel: (01) 614 7020 Lo Call: 1890 289 389 E-mail: wcu@hsa.ie Web: www.hsa.ie

IRISH EXPORTERS ASSOCIATION Tel: (01) 661 2182 E-mail: iea@irishexporters.ie Web: www.irishexporters.ie

HEALTH RESEARCH BOARD Tel: (01) 234 5000 E-mail: hrb@hrb.ie Web: www.hrb.ie

IRISH MEDICAL DEVICES ASSOCIATION Tel: (01) 605 1564 E-mail: firstname.surname@ibec.ie Web: www.ibec.ie/imda

HIGHER EDUCATION AUTHORITY Tel: (01) 231 7100 E-mail: info@hea.ie Web: www.hea.ie

IRISH MEDICINES BOARD Tel: (01) 676 4971 E-mail: customerservice@imb.ie Web: www.imb.ie IRISH NATIONAL ACCREDITATION BOARD Tel: (01) 607 3003 E-mail: info@inab.ie Web: www.inab.ie

IDA - INDUSTRIAL DEVELOPMENT AGENCY Tel: (01) 603 4000 E-mail: idaireland@ida.ie Web: www.idaireland.com

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IRISH VENTURE CAPITAL ASSOCIATION Tel: (01) 276 4647 E-mail: secretary@ivca.ie Web: www.ivca.ie INVEST NORTHERN IRELAND Tel: (01) 234 2533 E-mail: eo@investni.com Web: www.investni.com MANDATE TRADE UNION Tel: (01) 874 6321 E-mail: mandate@mandate.ie Web: www.mandate.ie NATIONAL INSTITUTE FOR TRANSPORT & LOGISTICS (NITL) Tel: (01) 402 3000 E-mail: nitl@dit.ie Web: www.nitl.ie PARENTERAL DRUG ASSOCIATION (PDA) Tel: +1 (301) 656 5900 E-mail: info@pda.org Web: www.pda.org PHARMACHEMICAL IRELAND Tel: (01) 605 1584 E-mail: pharmachemicalireland@ibec.ie Web: www.pharmachemicalireland.com Pharmaceutical society of Ireland Tel: (01) 218 4000 E-mail: info@thepsi.ie Web: www.thepsi.ie REPAK Tel: (01) 467 0190 E-mail: info@repak.ie Web: www.repak.ie SCIENCE FOUNDATION IRELAND Tel: (01) 607 3200 E-mail: info@sfi.ie Web: www.sfi.ie




Supply Chain

Securing the Supply Chain Maria Svejdar, Marketing Manager, GS1, examines how the adoption of GS1 standards-based product and asset identification systems, coupled with EDI, greatly enhances the ability of all parties to secure the chain of custody, of both raw ingredients and finished products throughout the healthcare supply chain.

C

utting supply chain costs to improve profitability has never been more of a priority for Irish pharmaceutical companies, competing with overseas plants for survival. Throughout the sector, companies are looking for ways to re-engineer their processes, to drive out inefficiencies and to create greater visibility and security across their supply chains. Supply chain visibility is about knowing where objects (e.g. raw materials, their containers, as well as finished goods and assets) are and where they have been. When combined with easy access to production data, such as expiry dates or batch numbers, manufacturers can transform into highly responsive, flexible and lean organisations. Visibility means leveraging standards and business applications to see more “event-based” product information, which is critical for dynamic inventory management, tracking, tracing and product authentication, as well as meeting regulatory requirements.

Serialisation Regulations The pending serialisation regulations, which will require the serialisation of medicines and medical devices, will require significant investment, but the resulting visibility of product across the supply chain will more than compensate in terms of reduction of out-of-stocks and product wastage, improved expiration management, efficiency gains, and critically, patient safety. Linking and validating the physical flow of raw materials and goods with production data about them can only be successfully achieved through the adoption of open, global standards. Manufacturers are looking to enabling technologies such as bar-coding, RFID and electronic messaging (EDI) to automate processes, enhance visibility and enable interoperability. Indeed the adoption, by upstream raw materials suppliers, of GS1 standards-based product and asset identification systems, coupled with EDI, greatly enhances the ability of all parties to secure the chain of custody, of both raw ingredients and finished products throughout the healthcare supply chain.

Case Studies A number of Irish organisations are already to the fore in deploying standards-based solutions for product identification, authentication, traceability and supply chain visibility. An Irish Product Authentication and Traceability Best Practice Solution

The National Centre for Hereditary Coagulation Disorders has implemented a world-class warehousing, distribution, stock management and traceability system based on GS1’s open, global standards. The solution, which tracks medication used for the treatment of haemophilia, is regarded internationally as best practice. The system has delivered a return on investment within a very short timeframe, reducing wastage and very significantly eliminating over €5m in surplus stock from the supply chain. The system is also being further developed to extend the traceability capabilities right to the point of administration in the patient’s home. A new mobile phone app enables patients to check a product’s expiry and recall status and following treatment, the app updates both the electronic patient record and the warehouse management system, ensuring a constant cycle of real-time product and data visibility.

CLASS Demonstrates Visibility and Interoperability

Late last year, The Galway Clinic in conjunction with GS1 Ireland, Georgia Tech Research Ireland, the Western Vascular Institute and three of the top endovascular device manufacturers piloted a GS1 EPC standards-based RFID supply chain visibility solution. The aim of the project was to develop a model for endovascular-device tracking to include RFID technology and bar codes from the point of manufacture to the operating room, to improve supply chain efficiency and reduce the cost of missing or expired items. “With 10 to 20 procedures performed each day, the last thing surgeons need to worry about is whether the right product is in stock or if it has passed its expiry date,” said Sherif Sultan, the clinic’s consultant vascular and endovascular surgeon. “The CLASS project demonstrated that UHF RFID tags could identify and track the movement of high-value endovascular devices to improve patient safety and lower costs by reducing the risk of errors, outof-stocks and product expiration,” said Kevin McGuinness, Senior Project Manager at Georgia Tech Ireland.

For further information on GS1 Standards for unique product, asset and location identification within the Pharma-Chemical industry please call 01 2080660. 9