What Are Capillary Columns And Factors Required For The Selection Of Capillary Columns? Capillary columns are gas chromatography columns coated with their inner surfaces. They are not packed into the cavity. Capillary GC columns are best to analyze individual chemical compounds and have more separation of the samples as compared to packed column because it is overloaded with too many samples. In case you need to test impurities in petroleum and pharmaceutical capillary column is used. With columns, an optimized chromatographic separation begins.