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Professional Opinion: Hunter Skelton, Student Pharmacist

“Although not everyone has used ecstasy, many people have probably heard about it. MDMA is being considered for therapeutic use in certain patient populations. Putting stigma aside and testing MDMA in safe and ethical ways might prove its efficacy in psychotherapy. It should always be remembered that ecstasy off the street may not be pure, and therefore can be very dangerous to unsuspecting users. Negative effects from polydrug use may lead to some of the stigma associated with ecstasy, but the use of any substance can cause harm.” doi:10.1111/adb.13000 https://www.drugfoundation.org.nz/matters-ofsubstance/archive/matters-of-substance-november2014/about-a-drug-mescaline/

2. Kalant H. The pharmacology and toxicology of "ecstasy" (MDMA) and related drugs. CMAJ. 2001;165(7):917-928.

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3. NIDA. MDMA (Ecstasy/Molly) DrugFacts. National Institute on Drug Abuse website. https://nida.nih.gov/publications/drugfacts/mdmaecstasymolly. June 15, 2020 Accessed October 13, 2022.

4 Hardey S, Thomas S, Stein S, Kelley R, Ackermann K. Is Ecstasy (MDMA) Addictive? American Addiction Centers.

5.Drug Interactions. IBM Micromedex Solutions. Truven Health Analytics, Inc. Ann Arbor, MI. Accessed October 13, 2022.

6.Mori T, Iwase Y, Uzawa N, et al. Synergistic effects of MDMA and ethanol on behavior: Possible effects of ethanol on dopamine D2receptor-related signaling. Addict Biol. 2021;26(4):e13000.