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Ergotism, also called St. Anthony’s Fire, causes hallucinations, loss of limbs, and death
Cytochrome P4503A4 inhibitors: Drugs that inhibit CYP34A may increase the risk of ergot toxicity (e.g., amiodarone, clarithromycin, diltiazem)
Ergot derivatives: Increase risk of adverse effects when used with ergot. (e.g., bromocriptine, dihydroergotamine, ergotamine)
Serotonergic drugs: Ergot derivatives act as serotonin agonists, so using them with serotonergic drugs may increase risk of serotonergic side effects such as Serotonin syndrome, cerebral vasoconstrictive disorders) (e.g., fluoxetine, sertraline, sumatriptan)
Stimulant drugs: May increase the risk of vasoconstriction (e.g., albuterol, dopamine, pseudoephedrine )
Drug Screens
The MycoSep® 150 Ergot test is used to find ergot alkaloids in all food and feed commodities.
REVEAL® Q+MAX is a simple rapid lateral flow test to identify ergot alkaloids.
