12 minute read
New Products
Pump
Watson-Marlow Pumps Group launches its 520Di dispensing pump for accurate metering, dosing and transferring of sensitive fluids in sanitary environments. Ideal for filtration, fermentation and dispensing applications, the 520Di accepts eight different tubing materials and sizes up to 9.6mm for flow rates ranging from 4 microlitres/min up to 3.5 litres/ min and pressures up to 100 psi. The 520Di combines the rugged ability to perform in process applications with dispensing and dosing programming to handle the most delicate laboratory environments and the accuracy demanded in filling lines in Biotech and Pharmaceutical production. The 520Di is also suited for benchtop media or reagent preparation in laboratory suites; filling or inoculating bottles, vials, petri dishes and media bags. Up to 50 individual dispensing programs, including all dose parameters and calibration, can be stored in the memory with full, 8-character file names. Equipped with a brushless DC motor, it has a speed range of 3500:1 and over a million to 1 flow range, offering total flexibility of speed control combined with precision and repeatability for the most demanding dispensing applications. A number of different pump heads can be fitted to suit the user’s needs. Combining extraordinary levels of functionality with an on-screen menu, the 520Di features an easy-to-use tactile membrane keypad and an alphanumeric display in English, German, French, Spanish and Italian.
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Software
Eppendorf announces the latest version of its PC software for controlling the epMotion automated pipetting system. EpBlue ID™ incorporates a new barcode management functionality to provide secure sample tracking. Operating and programming is easy and fast – even complex methods can be generated in minutes with intuitive menus and a tab-based structure that guides the user through the software functions. An unprecedented ease of use is capable through pipetting pattern recognition, a pre-defined labware database, and built-in and organized liquid classes. This latest version of the epMotion operating system is specifically for users working in regulated areas where sample safety and the requirement to track and document each individual specimen are of paramount importance.
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Software
The new Thermo Scientific BindIt 3.1 software has been developed for use with all Thermo Scientific KingFisher magnetic particle processor instruments. The software enables users to create new purification protocols or modify existing ones. Providing the highest possible throughput, the software also enables the KingFisher® Flex to interface with liquid handling and plate stacking instruments as well as robotics. With ready-made and validated purification protocols available, BindIt 3.1 software lets users choose the best method for a sample process. Once created, custom protocols can be stored in a PC database and transferred to the KingFisher instrument memory for stand-alone operation or run directly from the PC. All steps in the process have modifiable, defined parameters, and users can generate a status report to maintain quality control. This can include data on the run log, plate layout and step parameters.
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Power detector
Gigahertz-Optik introduces the ISD-1.6-Si-1 and ISD-1.6-SiFC-1 radiant power detector featuring a compact 16mm diameter integrating sphere for beam emitter type light sources like laser diode dyes and optical fibers. The small footprint 43.5 x 25 x 17.5mm size detector primary function is to fit inside existing equipment and tight enclosed spaces to measure beam power through its 3mm measurement port. The silicon photodiode detector offers a wide spectral range from 400 to 1100nm and a typical absolute sensitivity of 200 μA/W at 630nm (500 mW max power). The detector head is traceably calibrated and certified to international standards. The ISD-1.6-Si-FC-1 model includes a FC connector to allow connection of a spectrometer in case spectral data is required. The FC connector is mounted opposite the measurement port to collect the maximum amount of light signal for high resolution spectrometers with limited sensitivity. A near-infrared version with an InGaAs photodiode to cover the 800nm to 1700nm spectral range is also available.
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Pipetting instrument
The LCP technique for crystallizing membrane proteins can be difficult and time-consuming to set up by hand as it utilizes highly viscous lipid mesophases to reconstitute proteins. TTP LabTech has overcome these problems with mosquito LCP, a dedicated pipetting instrument for automated LCP screening set-up. This new product boasts the full functionality of the renowned mosquito product, whilst incorporating technical innovations specific for LCP techniques. Developed in collaboration with senior researchers from the MRC, UK; this instrument facilitates the automation and increased throughput of lipidic cubic phase (LCP) crystallization set-ups. Using a positive displacement syringe with automated tip positioning, mosquito LCP provides accurate and repeatable dispensing of the LCP drops. The precise positioning of the LCP material also facilitates automated imaging of membrane protein crystals in a range of high density plate types. For the precipitant additions step, this not only guarantees zero cross-contamination, but negates the need for time-consuming tip washing. Subsequently, high throughput rates of more than eight 96- well plates per hour are easily achieved and evaporation of the dispensed LCP is minimized.
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Turbopumps
Featuring a rotor design, HiPace Turbopumps provide reduced run-up time, higher gas throughput and exceptional compression for light gases. The compact HiPace, is offered in a variety of drive versions, including Profibus and DeviceNet, has integrated drive electronics, which reduces bulky and costly cabling. Innovative materials have doubled drive service life, while a proven Pfeiffer Vacuum bearing design ensures reliability, even in harsh applications. Available in pumping speeds from 10 to 700 l/s, HiPace can be installed in any orientation.
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NEw PRODuCTS
Spectrometer
The i-LABR hand-held analyzing spectrometer from MicrOptix Technologies has broad applicability for field research, laboratory, and process applications. The i-LAB features software that allows users to create customized spectral measurements and analysis routines for use in the i-LAB.The current i-LAB model measures the Visible light range (400700 nm). Several measurement methods for Quality Assurance/Control are included with the i-LAB. The i-LAB features several sample adaptor options for use with a variety of liquids as well as a surface reader adaptor for conducting solid surface reflectance measurements.
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Insertion Probe variant
Stratophase, a specialist in real-time chemical and biochemical measurement and detection, has collaborated with the Centre for Process Innovation (CPI) to develop an Insertion Probe variant of its unique SpectroSens system. Enabling real-time monitoring of the bioproduction fermentation process, the multi-output SpectroSens Insertion Probes track compositional changes and monitor temperature in the liquid. Multiple discrete readings can be taken simultaneously at numerous locations, providing more reliable measurements and a reduced chance of false positives. As a result, the entire fermentation process can be precisely monitored to ensure excellent reproducibility and clear determination of the desired end-point. The SpectroSens system sensors can be placed throughout the production process and networked via the control and analysis unit. Using only light at the point of measurement, the sensors are intrinsically safe and spark-free, removing any chances of ignition. The new Insertion Probe fits standard ports for dissolved oxygen (DO) and pH probes, enabling ultra-high resolution, optical microchip technology to be applied to existing benchtop and large-scale bioreactor equipment. Other applications of the new SpectroSens Insertion Probe include biofuel production and sustainable polymer development.
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Cell culture bioreactor
New Brunswick Scientifics’ new 5 and 14 litre CelliGen™ BLU benchtop cell culture bioreactor offers all the benefits of single-use technology with the trusted performance and true scalability of a stirred-tank design. A compact control station includes options for 4-gas mixing and multiple thermal mass flow controllers for producing high cell densities in research or GMP production. The singleuse vessel eliminates autoclaving and cleaning, provides rapid turnaround between runs and reduces risk of contamination. Its integrated control station enables advanced gas management and process control while its unique pH and DO technology makes probe insertion totally noninvasive, eliminating contamination risk and making probe autoclaving unnecessary.
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Calcium Assay Kit
Calcium flux assays are preferred methods in drug discovery for screening G protein coupled receptors (GPCR). The Screen Quest™ Calcium Assay Kit from amsbio provides a homogeneous fluorescence-based assay for detecting the intracellular calcium mobilization. Cells expressing a GPCR of interest that signals through calcium are pre-loaded with a fluorogenic cell-permeable calcium indicator which can cross cell membrane. Once inside the cell, the lipophilic blocking groups are cleaved by non-specific cell esterase, resulting in a negatively charged fluorescein dye that stays inside cells and its fluorescence is greatly enhanced upon binding to calcium. When cells stimulated with screening compounds, the receptor signals release of intracellular calcium, which greatly increase the fluorescence of the calcium indicator. The kit also provides an optimized assay method for monitoring G-protein-coupled receptors (GPCRs) and calcium channels. The assay can be performed in a convenient 96-well or 384-well microplate format and easily adapted to automation.
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Power Supply
Extech Instruments, a supplier of handheld test and measurement equipment, announces the new 382275 600 Watt switching mode DC bench power supply (120V). The new power supply is an easy-to-configure, highly stable, lab grade DC power supply with maximum output power of 600W. It offers two degrees of control over both current and voltage outputs; coarse and fine. Output is adjustable from 0 to 30V DC and 0 to 20A with (0.1V/A resolution). Dual green LED displays offer easy-to-read, high contrast readouts of voltage and current values. The Extech 382275 offers four operating modes: normal mode, with values controlled by front-panel knobs; preset mode, which offers three popular voltage presets at 20A: 5.0V, 13.8V, and 25V; set mode, with three user-customizable presets; and remote control mode, where the user can remotely adjust output power on/off, voltage and current. Other features include automatic constant current and voltage, high RFI immunity, excellent EMI, a thermostat-controlled variable speed fan, as well as over-voltage, over-temperature, and short circuit protection. The 382275 offers a compact, low profile design and small footprint (7.9 x 3.5 x 8.5 in., 200 x 90 x 215 mm; 5.7 lbs, 2.6 kg) without compromising output noise and transient response factors.
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Automated cell counter
Millipore Corporation introduces its Scepter™ handheld, automated cell counter. Scepter miniaturizes coulter cell counting technology found in much larger instruments into a portable device the size of an automated pipette. The instrument contains sophisticated electronics for cell sensing, signal processing, and data storage. A graphical display reports the cell count and average cell volume within 20 seconds of inserting the tip into a cell culture sample. In addition to showing cell counts and average cell volume, the instrument also displays a histogram of cell distribution by volume or diameter. The histogram can be used to provide an instant snap shot of the health of the culture. Results can be stored on the instrument or downloaded to a computer.
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Vacuum gauge
BrandTech Scientific introduces a new vacuum gauge from VACUUBRAND®. The DCP3000 + VSP3000 uses the Pirani principle of thermal conductivity to measure in the fine vacuum range. It incorporates a new patent-pending VSP3000 transducer that is substantially more chemically resistant and mechanically robust than earlier designs, making it an excellent choice for both chemistry labs and process applications. The display module DCP3000 has the ability to connect up to three additional VSP3000 transducers. Automatic configuration of the display unit to gauge heads and solenoid valves is via VACUUBRAND’s VACUU•BUS plug-and-play system. Up to four additional VSK3000 capacitive gauge heads for the rough vacuum range can also be connected, for a total of up to eight transducers. A solenoid vent valve can be added to vent the application. The displayed pressure can be measured in your choice of units—Torr, millibar or hectoPascal. Digital and analog displays provide both precise readings and trend indication. A “turn-and-push” jogwheel interface allows for easy navigation of menus. The set includes 100-230VAC / 50-60Hz universal power supply with US, CEE, UK, CH and AUS plugs. Purchase through preferred laboratory supply dealers.
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