Precis Process Services Process Engineering + Architecture to Drive Production Pharmaceutical + Biotechnology Science + Technology Higher Education Industrial Corporate + Commercial Healthcare Food + Beverage Chemical Oil + Gas
Comprehensive Engineering + Architecture Services for continuity from concept through operations
ABOUT PRECIS Since 2005, Precis has maintained dual commitments to technical excellence and customized service for clients in the pharmaceutical + biotechnology, science + technology, higher education, industrial, corporate + commercial, and healthcare markets. From offices in Pennsylvania and North Carolina, we provide award-winning, comprehensive engineering and architecture services to support our clients’ business goals and operational priorities. We specialize in planning and design for performance-critical facilities and have built a reputation as a leader in compliance. An integrated approach and hands-on technical expertise guide every assignment. We collaborate with each other, our clients, and our industry colleagues to bring interdisciplinary experience and professionalism to every project and to ensure continuity from concept through operations. We excel at helping visualize and reimagine spaces with elegant, well-conceived, and strategic solutions responsive to schedules and budgets. We pride ourselves on becoming an extension of our clients’ teams, and we value relationships. More than 85% of our work is repeat business. Through mutual respect, we build trust while helping our clients achieve success. We are your trusted advisors.
RESOURCES WITH OUR CLIENTS IN MIND
Two locations:
A dynamic team of 150+ professionals:
100+ Engineers
Precis Commissioning
201 S. Maple Avenue, Suite 200 Ambler, Pennsylvania 19002
and technical staff
WBE commissioning services
and design staff
staff contracting services
Headquarters: Triangle Region:
1100 Crescent Green, Suite 100 Cary, North Carolina 27518
25+ Architects 38 States
of registration + growing
Strategic partnerships:
PMconnect, Inc.
We believe a design partner adds value when they understand the client’s perspective. Our ability to work with clients, understand the drivers that make their projects worthwhile, and assemble resources to meet their goals results in successful projects. We call this Creative Leadership and believe it is in short supply in the professional marketplace.
Award-winning company + projects:
Building Design + Construction Giants Consulting-Specifying Engineer MEP Giants Highwire Platinum Safety Award ISPE Facility of the Year Award for Sustainable Design Philadelphia Business Journal Soaring 76 Philadelphia Business Journal Best Place to Work
Open communication:
Website: precisengineering.com Email: precis@precisengineering.com Ambler, PA Headquarters: 215.540.9800 Cary, NC Office: 919.650.1820 Social Media:
PROCESS ARCHITECTURE Unique Solutions for Systems Optimization: The Precis process architecture team solves client technology and planning challenges. Our process architects lead facility programming, planning, and design of development, process, and technical support spaces. Coordinating closely with Precis process engineers, process architects provide responsive, insightful consulting to address project requirements from inception to execution. Our team fully evaluates user needs to identify solutions focused on client objectives, including first and operating costs, flexibility, safety, compliance, cleanliness, and aesthetics. The scope and complexity of our work spans from limited modifications or repurposing existing facilities to strategic and conceptual planning for large-scale endeavors. Project benefits include rapid translation of block flows and process descriptions to layout concepts; integration of GMP and client standards with concept development; planning and visualization for rapid concept development; and clear, concise communication of ideas with user groups. Precis serves as a project integrator, bridging from discipline concerns to project solutions and ensuring comprehensive design coordination.
Process Architecture Services: •
Upfront project design feasibility studies
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3D integration of equipment + process unit operations
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Site + facility master planning
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Building code reviews addressing life safety + specialized
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Project needs definition supporting owner User Requirement Specifications (URS)
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Project facilities programming
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Conceptual project planning
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Integration of cGMP requirements, agency guidelines, and owner standards in concept and full design development
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Layout development from client block flow/process flow diagrams
project criteria •
Detailed design + documentation to support full project execution
PROCESS ENGINEERING Strategies for Efficiency and Quality: Precis process engineering services transform scientific innovation and manufacturing concepts into reliable, efficient, and compliant operations for life sciences, medical device, and industrial manufacturing. Our process engineers collaborate with clients and multidisciplinary design teams to develop manufacturing solutions that balance product quality, operational performance, facility requirements, and regulatory expectations. Our capabilities include process development support, technology evaluations, feasibility studies, process safety assessments, capacity planning, process modeling, equipment specification, utility integration, and detailed process design. Working seamlessly with our automation, mechanical, electrical, plumbing, and architectural disciplines, we deliver facilities where manufacturing processes, infrastructure, and operations function as a unified system. From conceptual planning and front-end engineering through commissioning, startup, and operational optimization, we help clients reduce risk, improve productivity, accelerate project delivery, and position manufacturing facilities for future growth.
Process Engineering Services: •
Process flow diagrams (PFDs)
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Downstream recovery
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Process development, characterization/optimization, validation
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Single-use + continuous processing
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Piping + instrumentation diagrams (P&IDs)
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Chemical synthesis, solvent handling + recovery
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Operational excellence + optimization
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Aseptic fill/finish, OSD, and semi-solids
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Highly potent API containment
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Biosafety Level (BSL) + Animal Biosafety Level (ABSL) facilities
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Capacity analyses + scale-up planning
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Risk assessments
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Superskid + module design
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Hazard + operability (HAZOP) reviews
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Equipment + user requirement specifications (URS)
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Energy modeling + conservation strategies
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Cell culture + microbial fermentation
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Process water systems
PROCESS VALIDATION Comprehensive, Data-Driven Manufacturing Process Development and Validation: Precis helps clients establish robust, reliable, and scalable manufacturing operations. Through Critical-to-Quality (CTQ) and Critical Process Management (CPM) methodology, we identify the variables that drive product quality and operational performance, enabling development of a scientifically justified and statistically supported manufacturing process operating window. Our approach goes beyond process optimization. We partner closely with our clients’ quality organizations to ensure process development, characterization/optimization, and validation activities fully align with quality system requirements, regulatory expectations, and business objectives. By integrating engineering excellence with quality-by-design principles, we create manufacturing processes that are capable, compliant, and sustainable throughout the product lifecycle. Whether supporting regulated industries or non-regulated manufacturing environments, our team has the technical expertise to develop, optimize, qualify, and validate processes that consistently deliver quality, reliability, and long-term manufacturing success. The results minimize risk, improve operational performance, and support future scale-up, technology transfer, and growth.
Validation Service Deliverables:
“Over the last 15 years, I've worked with Precis on many large- and small-scale projects within the
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Equipment I/OQ
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Equipment site acceptance testing (SAT)
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Manufacturing process development
project staff being very responsive and easy to work
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Manufacturing process characterization + optimization
with, one of the things I value the most is that their
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Process operational qualification (POQ)
designs are both innovative and practical. Precis is a
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Process performance qualification (PQ)
valued and trusted teaming partner that I am proud to
pharmaceutical and biotech industries. Aside from the
work with on any project." - Construction Management Client
Headquarters:
201 South Maple Ave., Suite 200 Ambler, PA 19002