Epithalon anti-aging agent, a telomerase activator! -By Polypeptide.ltd
Authoritative source：PubChem
Introduction Epithalon, also known as Epitalon, Epithalone, or Epithalamin, is a short synthetic peptide with the ability to activate the telomerase enzyme and stimulate melatonin release. Originally developed in Russia during the 1980s, Epithalon has demonstrated the ability to delay age-related changes in the reproductive and immune systems, as well as extend the lifespan of mice and rats. While its primary focus is in anti-aging research, Epithalon has also shown promising effects in certain types of cancer, infectious diseases, and DNA regulation.
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Epitalon powder synthesis Epitalon is considered the “fountain of youth” peptide. It is a tetra-peptide, which means that it is composed of four amino acid chains. The peptide is used to regulate the cell cycle during telomerase activity. Telomerase, also called telomere terminal transferase, is an enzyme made of protein and RNA subunits that elongates chromosomes. When telomerase activity is not present (when we age), our cells age. Our telomeres get shorter and begin to die off. If telomerase is activated in our cells, our telomeres lengthen, the cell continues to grow and divide, delaying the aging process. Epitalon is synthetic peptide. It is administered as a subcutaneous injection and is available in Polypeptide.ltd in raw powder form and lyophilized powder form. Epitalone raw powder form Epitalon powder refers to the active ingredient powdered form of the marketed drug Epitalon 5mg, 10mg, 100mg. Epitalon raw powder is the raw material to produce lyophilized powder Epitalon in vials. It is not ready for individuals to use. Only for research. Reconstitution(Epitalon finished vials) Epitalon lyophilized powder form is ready for reconstitution. This lyophilized powder is typically provided in vials or vial kits. The lyophilized powder is then mixed with a suitable diluent, such as bacteriostatic water or sterile water, to create a solution for injection. Reconstitution instructions may vary depending on the specific product and Epitalon peptide manufacturer,so it is important to carefully follow the provided guidelines.
How does Epitalon works 丨 The Mechanism Of Action Of Epitalon Peptide Epitalon peptide works in the pineal gland of the brain. Its primary role is to increase the natural production of telomerase, a natural enzyme that helps cells reproduce telomeres, which are the protective parts of our DNA. This allows the replication of our DNA, so the body can grow new cells and rejuvenate old ones. It has shown a 33% increase in telomere length in somatic cells. It has many documented effects on general aging and impacts on the circadian rhythm. It promotes a
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natural cycle and healthy sleep cycles, it also makes sure that cortisol and other stress hormones are not elevated throughout the day, which can lead to excess abdominal weight gain. It helps regulate levels of melatonin and cortisol. It helps make sure cortisol is elevated in the morning and melatonin is elevated in the evening. In addition to protecting telomeres from deterioration, Epitalon peptide has been shown to have antioxidant and anti-inflammatory properties that can help reduce cellular damage caused by exposure to environmental toxins or oxidative stressors.
Epitalon dosage – How to use Epitalon petide? Epitalon peptide exhibits minimal side effects, low oral and excelletn subcutaneous bioavailability in mice. Per KG Epitalon dosage in mice does not scale to humans. Epitalon for sale at polypeptide.ltd is limited to educational and scientifica resarch use only, not for huamn consumption. Only buy Epitalon peptide if you know it.[6] Due to the short length of the amino-acidic chain, epithalon is administrated orally, nasal spray drops or injectable (by far the most effective method) in 10 – 20 days-in-row cycles. Oral administration: 2 – 8 mg/day, 2 – 3 servings per day Nasal administration: 1 – 5 mg/day, 3 servings per day Injectable administration: 0.5 – 3 mg/day, 1 – 2 injections per day (intramuscularly or subcutaneously) When taking Epithalon, or any other phenylethylamine derivative, it’s important to adhere to recommended Epitalon dosage guidelines in order to avoid potential side effects, ensure effectiveness, and monitor your body’s response. It is always recommended to speak with your medical provider before beginning any new protocol or changing your existing one.
Reference citations [1] V. N. Anisimov, S. V. Mylnikov, and V. K. Khavinson, “ Pineal peptide preparation
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epithalamin increases the lifespan of fruit flies, mice and rats,” Mech. Ageing Dev., vol. 103, no. 2, pp. 123–132, Jun. 1998.
[PubMed]
[2] V. K. Khavinson, I. E. Bondarev, and A. A. Butyugov, “Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells,” Bull. Exp. Biol. Med., vol. 135, no. 6, pp. 590–592, Jun. 2003. [PubMed]. [3] T. A. Dzhokhadze, T. Z. Buadze, M. N. Gaiozishvili, M. A. Rogava, and T. A. Lazhava, “[Functional regulation of genome with peptide bioregulators by hypertrophic cardiomyopathy (by patients and relatives)],” Georgian Med. News, no. 225, pp. 94–97, Dec. 2013. [PubMed]
[4] V. N. Anisimov et al., “Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice,” Biogerontology, vol. 4, no. 4, pp. 193–202, 2003. [PubMed] [5] V. K. Khavinson, S. I. Tarnovskaya, N. S. Linkova, V. E. Pronyaeva, L. K. Shataeva, and P. P. Yakutseni, “ Short cell-penetrating peptides: a model of interactions with gene promoter sites,” Bull. Exp. Biol. Med., vol. 154, no. 3, pp. 403–410, Jan. 2013. [PubMed]
[6] N. S. Lin’kova, B. I. Kuznik, and V. K. Khavinson, “[Peptide Ala-Glu-Asp-Gly and interferon gamma: their role in immune response during aging],” Adv. Gerontol. Uspekhi Gerontol., vol. 25, no. 3, pp. 478–482, 2012. [PubMed]
[7] N. I. Chalisova, N. S. Lin ’ kova, A. N. Zhekalov, A. O. Orlova, G. A. Ryzhak, and V. K.
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Khavinson, “ [Short peptides stimulate skin cell regeneration during ageing], ” Adv. Gerontol. Uspekhi Gerontol., vol. 27, no. 4, pp. 699–703, 2014. [PubMed] Author of this article: Dr. Jean Zeng graduated from king's college london Faculty of Life Sciences & Medicine. Scientific Journal paper Author: Stephen C. Bain Diabetes Research Group, Swansea University Medical School, Swansea, SA2 8PP, UK Department of Diabetes and Endocrinology, Singleton Hospital, Swansea Bay University Health Board, Swansea, SA2 8QA, UK In no way does this doctor/scientist endorse or advocate the purchase, sale, or use of this product for any reason. Polypeptide.ltd has no affiliation or relationship, implied or otherwise, with this physician. The purpose of citing this doctor is to acknowledge, acknowledge and commend the exhaustive research and development work done by the scientists working on this peptide.
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