The role of Nicotinamide Riboside Chloride(NRC) is in aging and energy improvement as NAD boosters

Phcoker

Xuchang shangke Chemical Co., Ltd

www.phcoker.com

The Role Of Nicotinamide Riboside Chloride Is In Aging And Energy Improvement As NAD Boosters

The health and anti-aging industry is a global trillion-dollar industry. It is no secret that people spend huge amounts of money on anti-aging products every year.

There are many anti-aging products on the market with many brands. However, research on aging, especially nicotinamide adenine dinucleotide(NAD) fortified supplements including nicotinamide riboside(NR) and nicotinamide mononucleotide(NMN), has been conducted for many years, proving that their anti-aging effects are amazing.

So how much do you know about aging and nicotinamide riboside chloride?

Aging (1)What is Aging?

Aging refers to the phenomenon that the body's ability to adapt to the environment gradually decreases and gradually tends to death. Aging can be divided into two categories: physiological aging and pathological aging. The former refers to the physiological degeneration process that occurs after the mature period, and the latter is the aging changes caused by various external factors (including various diseases).

The two are actually difficult to distinguish. In short, aging is the inevitable result of the comprehensive effects of many pathological, physiological and psychological 1

Email: info@phcoker.com

Phcoker

Xuchang shangke Chemical Co., Ltd

www.phcoker.com

processes, and is the biological and psychological process of the final stage of individual growth and development.

In humans, aging represents the changes accumulated by humans over time, and can cover physical, psychological, and social changes. For example, as time grows, reaction time may slow down, and understanding of world events and wisdom may expand.

Aging is one of the biggest known risk factors for most human diseases: about 150,000 people die every day in the world, about two-thirds are due to age-related causes. In industrialized countries, this proportion is even higher, reaching 90%.

(2)Why is it aging?

The term aging (Aging or Senescence) means the degenerative changes that gradually appear in the body as we age. The universality, internal cause, progress and harmfulness of aging are generally accepted as the standards of aging. Since the application of experimental methods to study aging at the end of the 19th century, there have been no fewer than 20 theories put forward, and many theories have not been supported by experimental studies. Current research believes that aging is the result of comprehensive factors such as stem cell decline, DNA degradation, dietary spiritual factors, and active aging genes. A unified theory of aging has not yet been formed.

(3)How to reverse aging?

Although aging is inevitable, it is possible to delay aging. Reasonable diet and

2

Email: info@phcoker.com

Phcoker

Xuchang shangke Chemical Co., Ltd

www.phcoker.com

balanced nutrition are one of the important measures to delay aging and prolong life.

In addition, people can also delay aging by supplementing some products with anti-aging properties. This type of supplement products can be in the form of health care products for internal use (such as powders, capsules and tablets), or in external forms such as cosmeceutical products (such as essences or creams).

Nicotinamide Riboside (NR) chloride (NIAGEN) is a derivative of NR and chlorine. The compound augments the levels of NAD+ and activates SIRT1 and SIRT3. It reverses aging by enhancing oxidative metabolism and countering diet-related metabolic comorbidities.

In the US, nicotinamide riboside chloride is generally recognized as safe. Therefore, it is an approved dietary ingredient for use in protein shakes, vitamin waters, gums, and related supplements.

The importance of NAD in anti-aging NAD+ is a molecule that supports cell function in many important ways and is essential for cell metabolism. It can keep our DNA healthy, convert food into usable energy and regulate our sleep/wake cycle. Once the level of NAD+ in our body drops, it means that our body functions begin to deteriorate, and diseases (heart disease, type 2 diabetes, Alzheimer's disease, etc.) and aging will follow.

Through diet, the NAD + intake in all of us increases the content of NAD + precursors.

NR is a form of vitamin B3. There are dozens of food sources that can provide vitamin B3. However, compared with other forms of B3 in the diet, nicotinamide ribose 3

Email: info@phcoker.com

Phcoker

Xuchang shangke Chemical Co., Ltd

www.phcoker.com

chloride is absorbed relatively quickly in the body. This makes it one of the most reliable and effective ways of NAD+ supplementation in the human body.

How can we increase my NAD naturally?

(1)Food or supplement Nicotinamide Riboside (NR) is a nucleoside made out of niacinamide and ribose. It is a form of Vitamin B3, which is also called niacin or nicotinic acid. It can be found in cow’s milk, brewer’s yeast, and whey protein. We can eat more NR-rich foods in our daily lives, or we can also get the NAD+ that our body needs by taking NRC supplements.

(2)How to take nicotinamide riboside chloride?

Nicotinamide riboside chloride is available in powder, tablet or capsule form and is commonly called niagen. It is available at select health-food stores, on Amazon or through online retailers.l.

Most NRC supplement brands recommend taking 250–300 mg per day, the equivalent of 1–2 capsules per day depending on the brand.

Is there anything I need to take care when taking nicotinamide riboside chloride? ♦Studies have shown that the constant recommendation for dosage remains the same regardless of age. ♦Studies have shown that the NAD+ in patients who take 300mg per day and 1000mg 4

Email: info@phcoker.com

Phcoker

Xuchang shangke Chemical Co., Ltd

www.phcoker.com

per day are significantly increased, so regardless of the length of use, the dosage of NR only needs to be kept within the standard dosage, and there is no need to overuse it. ♦There are few studies on NAD-related gene mutations and how taking vitamin B3 (also known as NRC) can help pregnant mothers, so pregnant women are advised not to use such products. If you want to use it, please consult a doctor. ♦There are currently no known interactions of NRC with other drugs, but it is always important to contact your health professional before starting a new supplement.

How to choose a suitable nicotinamide riboside chloride product?

There are many nicotinamide riboside chloride manufacturers on the market, and there are many NRC brands, but they mainly appear in three forms: powder, capsule and tablet. It may be used purely for medicinal purposes as a main ingredient, or it may be added to some health foods. What's more, you may find it in some anti-aging products. However, no matter what form it appears in, when you try to use it, you must first have a comprehensive understanding of your health, and secondly, do some investigations on the company that produces the product and choose a reputation guarantee merchants with high-quality raw materials will eventually buy this product that makes you healthier and younger.

Reference [1]Bowen RL, Atwood CS (2004). "Living and dying for sex. A theory of aging based on 5

Email: info@phcoker.com

Phcoker

Xuchang shangke Chemical Co., Ltd

www.phcoker.com

the modulation of cell cycle signaling by reproductive hormones". Gerontology. 50 (5): 265–90. doi:10.1159/000079125. PMID 15331856. S2CID 18109386.

[2]Trifunovic A, Larsson NG (February 2008). "Mitochondrial dysfunction as a cause of ageing". Journal of Internal Medicine. 263 (2): 167–78. doi:10.1111/j.1365-2796.2007.01905.x. PMID 18226094. S2CID 28396237.

[3]Chi Y, Sauve AA. Nicotinamide riboside, a trace nutrient in foods, is a vitamin B3 with effects on energy metabolism and neuroprotection. Curr Opin Clin Nutr Metab Care. 2013 Nov;16(6):657-61. doi: 10.1097/MCO.0b013e32836510c0. Review.

PubMed PMID: 24071780.

[4]Bogan KL, Brenner C. Nicotinic acid, nicotinamide, and nicotinamide riboside: a molecular evaluation of NAD+ precursor vitamins in human nutrition. Annu Rev Nutr.

2008;28:115-30. doi: 10.1146/annurev.nutr.28.061807.155443. Review. PubMed PMID: 18429699.

6

Email: info@phcoker.com