Is Nicotinamide Riboside Chloride The Same As Vitamin B3?

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Is Nicotinamide Riboside Chloride The Same As Vitamin B3?

A balanced diet of macronutrients and micronutrients is the foundation of health and well-being. Together with a healthy lifestyle (including physical exercise and exercise), it can prevent or delay the onset of metabolic diseases.

Millions of people around the world take vitamins as nutritional supplements every day, and this industry is booming. One of the supplements, vitamin B3, is known to be effective against pellagra (a disease caused by malnutrition). Recently, some vitamin B3 preparations have attracted attention because of their ability to resist symptoms of metabolic diseases and aging in pre-metabolism clinical studies. NRC is one of them. Let us take a look at some information about vitamin B3 and NRC, and see what benefits they have for us.

What is Vitamin B3?

Vitamin B3 is a vitamin family, mainly found in animal internal organs, muscle tissues, fruits and egg yolks, and also in trace amounts. It is one of the 13 essential vitamins for the human body. It includes three forms or vitamins: niacinamide (niacinamide), niacin (niacin) and nicotinamide riboside. All three forms of vitamin B3 are converted into nicotinamide adenine dinucleotide (NAD) in the body. NAD is necessary for human life. Without vitamin B 3 or tryptophan, people would not be able to make NAD in the body. Nicotinamide riboside was identified as a form of vitamin B 3 in 1

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2004.

The role of Vitamin B3 in the human body Vitamin B3 is a class of organic compounds necessary to maintain the normal life of the human body. The content in the body is very small, but it plays a very important role in the body's metabolism, growth and development. It can improve the microcirculation of the whole body and is good for various diseases. Especially for heart, brain, kidney, vascular diseases and high blood pressure, and has skin health and beauty effects. Once the human body lacks this vitamin, it may cause pellagra, glossitis, dementia, diarrhea and other diseases.

Is Nicotinamide riboside chloride Vitamin B3?

Nicotinamide riboside was identified as a form of vitamin B 3 in 2004.

Vitamin B3 contains a group of molecules that can act as precursors to the classical enzyme cofactor nicotinamide adenine dinucleotide (NAD), which is composed of niacin (NA), nicotinamide (NAM) and the recently discovered nicotinamide mononuclear(NMN) and nicotinamide ribose (NR). NAD is the main mediator of cell energy metabolism, and it is also an important link between nutrient intake, cell metabolism and health.

All vitamin B3 have the ability to increase NAD+ levels to a certain extent. Each vitamin B3 molecule has a different metabolism in the human body, and its ability to increase NAD+ levels and prolong lifespan is also different. In order to obtain more 2

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NAD+ and increase the dose of niacin, it is necessary to consider the side effects related to the dose, because the side effects will limit the function of vitamin B3.

The latest preclinical studies have proved that among niacin, nicotinamide and nicotinamide ribose, nicotinamide ribose is not only the most effective NAD+ precursor, but also the most effective in extending life.

The benefits of Ncotinamide riboside chloride NR is naturally occurring and is the booster of NAD+. It has great potential for the human body.

(1)Easily Converted Into NAD+ NAD+ is a coenzyme or auxiliary molecule involved in many biological reactions.

Although this is essential for maintaining optimal health, studies have shown that NAD+ levels continue to decline with age. Low NAD+ levels are related to aging and various harmful diseases.

One way to increase NAD+ levels is to consume NAD+ precursors (components of NAD+), such as nicotinamide riboside. Animal studies have shown that nicotinamide ribose can increase the NAD + content in the blood by as much as 2.7 times.

Moreover, it is easier to use for your body than other NAD+ precursors and is the most effective NAD+ booster.

(2)Help Anti-aging One of the key Nicotinamide riboside chloride uses includes promoting healthy aging.

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The compound leads to an increase in NAD production, which plays a significant role in the cell. For instance, it raises the cellular energy levels within the muscles, liver, and kidneys.

The increased production of NAD+ in the body may trigger the production of certain enzymes that may help to enhance healthy and graceful aging. In animal studies, the coenzyme managed to trigger the production of an enzyme called sirtuins. Sirtuins can help to boost stress resistance in humans and repair damaged DNA as well.

Besides, Nicotinamide riboside chloride prevents senescence by increasing the circulation of blood in these vital organs.

(3)Neuroprotection Within brain cells, NAD+ helps control the production of PGC-1-alpha, a protein that appears to help protect cells against oxidative stress and impaired mitochondrial function. Researchers believe both oxidative stress and impaired mitochondrial function are linked to age-related brain disorders such as Alzheimer’s and Parkinson’s disease. When NAD levels fall below optimum, your neurological system and cognitive health may be at stake. Take, for example, patients with Alzheimer’s disease exhibit a low concentration of NAD+ and mitochondria dysfunction.

Among the clinical nicotinamide riboside chloride uses, the management of neurodegeneration in aging tops the list. The drug acts against intracerebral damage, ischemic stroke, neurological inflammation, and neuronal death.

(4)Nicotinamide Riboside Chloride May Help with Heart Problems

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The risk of heart failure increases significantly with age. Heart failure is also a very common problem. In fact, it is the number one cause of death worldwide. Although including proper diet and exercise, overall heart health depends on many factors. But some things may reduce the risk. The increase in NAD+ production is one of them.

In studies on animals and humans, it has been found that increasing NAD + by taking nicotinamide riboside can help reverse age-related arterial changes, and help reduce aortic stiffness and contraction in adults at risk of hypertension. Pressure.

(5)Healthy Metabolism for Managing Obesity Scores of research have proven the efficacy of nicotinamide riboside chloride in reducing weight. Users can lose up to 10% of their body fat without appetite suppression or physical training.

Taking the drug helps lower LDL cholesterol while raising the levels of good cholesterol. This happens when it holds back the action of the enzymes responsible for the synthesis of triglycerides. Consequently, the production of low-density lipoproteins slows down.

Nicotinamide riboside chloride benefits overweight patients with diabetes. The supplement boosts metabolism by improving glucose intolerance (6)Other benefits In addition, NRC can also repair damaged DNA and prevent oxidative stress, reducing the risk of cancer. It can also help treat jet lag or other circadian rhythm disorders, and may also have positive effects on promoting healthy muscle aging as well.

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How to incease Ncotinamide riboside chloride in body?

The NAD+ factor in the human body will gradually decrease with age, and aging and illness will also follow. In order to prevent diseases and delay aging, we can increase the level of life factors in the body by supplementing some vegetables, fruits and nutritional health products that are rich in NAD+ or NR. In foods, milk is the most common source of NR factors. NR is a natural product and a vitamin that has been hidden in milk. In addition, the fish, mushrooms and green vegetables that we often eat are also rich in NR factors. You can even find it in whey protein, brewer’s yeast and Whole Grains.

In addition, many nutritional supplements on the market also contain NRC ingredients, which may appear in different forms, which can be powders, capsules, tablets or preparations. You can get the NAD+ your body needs by taking these NRC supplements.

No matter which way to supplement NRC, it seems a amazing thing. Just choose the one that suits you best is the best.

Conclusion There is no doubt that a balanced diet is better than supplementary food as part of a healthy lifestyle. Although there is limited data or evidence on the use of vitamin B 3 supplements to improve human functions or obtain other health benefits in humans, when a balanced diet cannot achieve the NAD+ required by the human body, we can 6

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still supplement some of the richness appropriately. Supplements containing NRC, because it is natural, are safe for the human body.

Reference: [1]Khan, Nahid A, Mari Auranen, Ilse Paetau, Eija Pirinen, Liliya Euro, Saara Forsström, Lotta Pasila, et al. Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B 3 EMBO Molecular Medicine 6, no. 6 (April 2014): 721–31. https://doi.org/10.1002/emmm.201403943.

[2]Mehmel, M., Jovanovic, N., & Spitz, U. (2020). Nicotinamide Riboside – The Current State of Research and Therapeutic Uses.

[3]Mehmel, M., Jovanovic, N., & Spitz, U. (2020). Nicotinamide Riboside – The Current State of Research and Therapeutic Uses.

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