Toxemia

Toxemia Jared L. Zeff, ND, LAc Naturopathic Medicine Institute Scottsdale, Arizona Vital Gathering May 14, 2022

”He is likewise a preserver of health if he knows the things that derange health and cause disease, and how to remove them from persons in health.”

Samuel Hahnemann, The Organon, S4

“Accumulation of Morbid Matter and Poisons” This is the third of the primary causes of disease. We have learned how lowered vitality and the abnormal composition of the vital fluids favor the retention of systemic poisons in the body. If, in addition to this, food and drink contain too much of the waste-producing carbohydrates, hydrocarbons and proteins, and not enough of the eliminating positive mineral salts then waste and morbid materials are bound to accumulate in the system and this results in the clogging of the tissues with acid precipitates and earthy deposits.

Such accumulation of waste and morbid matter in blood and tissues creates the great majority of all diseases arising within the human organism.

Henry Lindlahr, Nature Cure, Chapter IV

Toxemia “The generation of toxic metabolites created by maldigestive, dysbiotic, intestinal bacterial metabolism of poorly digested food. These toxins enter the blood, irritate tissues, interfere with function, and become a basis for inflammation, chronic illness, autoimmune processes, infection, etc.”

Ancient Concept: Egyptian Medicine: described by Herodotus – disease begins in the colon Hippocrates – “On Ancient Medicine” dietary basis of disease.

The “Literature” For example: as early as 1879, Baumann demonstrated that Tyrosine is metabolized by gut bacterial to generate phenols and p-cresol.

(Baumann, E. (1879). Ber. Dtsch. Chem. Ges. 12, 1450.)

Phenols and p-cresol are implicated in tumor formation in mice.

Certain phenols are demonstrated convulsant agents in humans.

Toxemia 1924, Harke and Koessler demonstrated the generation of histamine by gut bacterial action on dietary amino acids.

(Urbach, K.F. (1949). Proc. Soc. Exp. Biol. (NY), 70, 146.)

Perry demonstrated the generation of the body burden of tyramine is entirely by gut flora. (Perry, T. L., et. al.

(1966). Clin Chem. Acta 14, 116.

Both histamine and tyramine are implicated in hypertension, suggesting that essential hypertension may be the result of “toxemia”.

Tryptophan metabolites generated by gut bacteria are implicated in bladder cancer.

Bryan, G. T. (1971). Amer. J. Clin. Nutr. 24, 841.

Toxemia 1974 – Drasar and Hill, Human Intestinal Flora Multiple pathways demonstrated of bacterial degradation of dietary elements and bile residues into toxic metabolites, absorbed into blood stream. Implications for cancer and chronic disease.

Tyrosine to Phenol (Human Intestinal Flora, Drasar and Hill, 1974)

Toxemia – an Example

Conversion of indole to indigo

Obermeyer - A Measure of Toxemia

2+ 4+

3+

Obermeyer Reagent 0.8 gm Ferric Chloride QS: 100 mL Concentrated HCl (37%) 2-3 cc Urine + 2-3 cc Obermeyer Reagent: 5 minutes to react

Optimal

Inflammation

Acoustic Cardiography Toxemia/Inflammation – digestive function Intestinal Function Heart function and Rhythm Hepatic Function Adrenal Function Thyroid Function General Health Indicators Baseline for comparison of progress or worsening

Acoustic Cardiography Nearly Perfect Tracing

Crohn’s Disease

Aortic

Mitral

Pulmonic

Tricuspid

Disease as Process Normal Health *Disturbing Factors

Discharge Process

Disturbance of Function Reaction (fever, inflammation, etc.)

Chronic Reaction Degeneration

Why Are People Sick • Weakened Vitality • Abnormal Composition of Blood and Lymph • Accumulation of morbid matter and toxins

4 Elements of Therapeutic Dietetics 1. Dietary Adequacy 2. Nutrient Balance 3. Dietary Reactivity 4. Dietary Supplementation

Dietary Reactivity Food Allergy IgE, IgG, IgM Alcat Testing (Cyto-toxic testing) Elimination/Challenge Food Intolerance (Toxemia) Carroll evaluation

What I learned Organized and ordered approach to therapy The real significance of wrong diet - toxemia Vitamins are suppressive (?)

The function of hydrotherapy The integrated use of homeopathic medicine The integrated use of botanicals

Therapeutic Order A. Address acute concerns *1. Identify and remove causes of disturbance (toxemia) 2. Establish a healthy regimen 3. Stimulate the self healing mechanisms 4. Support weakened or damaged systems 5. Correct structural integrity 6. Address pathology 7. Suppress pathology

Case 1 – Chronic Ear Infection 14 year old boy – the same ear infection since infancy.

Functionally deaf due to bone dissolution.

Could repair ears surgically if infection could be stopped.

Antibiotics ineffective.

A: no acute concerns 1. Identify a milk intolerance and remove from diet 2. Provided milk-free dietary information 3. Constitutional hydrotherapy 4. Digestive tonic, Kali mur 5. Manipulate neck and upper back

Infection cleared rapidly Three months: no infection Surgery to correct deafness Key: identify and remove cause: milk from the child of a dairy farmer

Asthma 5 year old girl Lots of colds: sick whole first year Breast fed x 3 months, then formula Asthma began 18 months: severe 🡪hospital Triggered by URI Controlled with flovent till age 3 URI 🡪 acute asthma attack 🡪 hospital

Also: enuresis slight bowel incontinence, occ. bloody, itchy rash on face, uncontrollable hunger gained 26 pounds in two years d/t steroids

Current regimen: Flovent bid Albuterol inhaler prn Flares require hospital ER & tx with steroids

Treatment Remove offending foods: Potato intolerance Dietary counseling: menu construction Daily hydrotherapy – 3 weeks Ant. Tart. 6c qid Lung tonic - tid Manipulate cervical/thoracic spine D/C flovent as improvement occurs Reduce inhaler use as improvement occurs

A Case of Asthma At one week: face less puffy Breathing fine cough for 3-4 days, now ceased No flovent using lung tonic using Ant tart. prn also Rash and continence unchanged

A Case of Asthma At week four: lost ½ pound, reduced appetite no further urinary incontinence mild asthma events with diet errors Ant. Tart. controls tendency toward asthma no need for albuterol

A Case of Asthma At week six: Acute SOB with cough – tx with ivy syrup * Dx: mild bronchitis (healing reaction) No asthma A four months No asthma events Growing taller, losing weight 2 years later: no asthma events with occasional URI

A Case of Asthma Address acute episodes: Ant. tart.

Identify and remove causes: potato (toxemia) Stimulate detoxification and healing: hydrotherapy Support distressed tissue (Lung): botanicals Improve structural integrity: manipulations

What caused the Ear Infection or the Asthma?

1. Case #1: Milk (toxemia) 2. Case #2: Potato (toxemia)

Naturopathic Medicine Institute Vital Gathering

“Toxemia” Jared L. Zeff, ND DrZeff@aol.com www.salmoncreekclinic.com