DENTISTS, SCIENTISTS & ENGINEERS TRANSFORMING ORAL HEALTH
Thursday, May 29, 2025
Penn Dental Medicine
University of Pennsylvania // Philadelphia, PA 19104 4TH
welcome
IT IS OUR GREAT PLEASURE TO WELCOME ALUMNI, FACULTY, STAFF, STUDENTS, AND FRIENDS TO THE FOURTH ANNUAL CENTER FOR INNOVATION & PRECISION DENTISTRY (CiPD) SYMPOSIUM.
The CiPD Symposium will celebrate dentists, scientists, and engineers transforming oral health. We warmly welcome our guest speakers, Dr. Drew Weissman, Dr. Joseph DeSimone, and Dr. Edward Zuckerberg. Dr. Weissman, 2023 Nobel Laureate in Medicine or Physiology, the Roberts Family Professor in Vaccine Research and Director of the Penn Institute for RNA Innovation at the Perelman School of Medicine, honors us by joining us for a fireside chat and delivering the morning plenary, “Nucleoside Modified mRNA-LNP Therapeutics.” Dr. DeSimone, the Sanjiv Sam Gambhir Professor of Translational Medicine and Chemical Engineering at Stanford University and Co-Director of the Canary Center, will deliver the afternoon plenary, “The Delicate Interplay Between Light, Interfaces and Design: The Complex Dance that Allows 3D Printing to Scale to Manufacturing.” Dr. Zuckerberg, Chief Executive Officer at Painless Social Media LLC and Venture Partner at Revere Partners, will lecture on “Bridging Oral Health & Systemic Wellness: Emerging Research & Future Innovations.”
Throughout the day, we will showcase CiPD faculty, trainees and students working on emerging applications and new affordable therapies — from craniofacial and tissue regeneration to oral microbiomes — using advanced materials, nano/biotechnology, mRNA, AI and robotics. A poster session competition will be featured during lunch.
We hope you enjoy, interact, and help us move forward in addressing the unmet needs to transform the future of oral health care.
HYUN (MICHEL) KOO KATHLEEN J. STEBE Co-Founding Director, CiPD Co-Founding Director, CiPD
INTRODUCTORY REMARKS
Hyun (Michel) Koo, DDS, PhD and Kate Stebe, PhD, CiPD Co-Founders/Co-Directors
8:45 am DEAN’S OPENING REMARKS // William W.M. Cheung Auditorium
Mark S. Wolff, DDS, PhD, Penn Dental Medicine
David F. Meaney, PhD, Penn Engineering
FIRESIDE CHAT // William W.M. Cheung Auditorium
Nucleoside Modified mRNA-LNP Therapeutics
9:00 am Drew Weissman, MD, PhD, 2023 Nobel Laureate in Medicine/Perelman School of Medicine/Penn Institute for RNA Innovations (Daeyeon Lee, PhD, Introduction)
Featuring CiPD NIDCR T90/R90 Fellows: Hagar Kenawy, PhD, Marshall Padilla, PhD, Zhi Ren, DMD, PhD
CiPD FACULTY SPEAKERS AND TRAINEE LECTURES // William W.M. Cheung Auditorium
10:00 am IDEA Prize (Daeyeon Lee, PhD, Introduction)
Kacy Cullen, PhD, Anh Le, DDS, PhD, Justin Burrell, PhD – Combining GMSC-Based Therapies and Axonal Fusion for Rapid Neuroprotection After Facial Nerve Trauma
10:25 am Hagar Kenawy, PhD (Mousa Younesi, PhD, Introduction) – Mending the TMJ: Combining Decellularized Matrix Technology and Progenitor Cells to Repair the Temporomandibular Joint
10:40 am Colgate – Palmolive // Coffee and Collaborative Discussion
11:05 am Ed Steager, PhD and Marc Miskin, PhD – Programmable Microscopic Robots for Targeting Biofilm Infection
ADVANCED MATERIALS FOR TRANSLATIONAL MEDICINE // William W.M. Cheung Auditorium
The Delicate Interplay Between Light, Interfaces and Design: The Complex Dance that Allows 3D Printing to Scale to Manufacturing
11:30 am Joseph M. DeSimone, PhD, Canary Center at the Stanford School of Medicine/Stanford Departments of Radiology and Chemical Engineering
LUNCH: Poster Session Contest // Lerner Pavilion and Fonseca Garden
12:30 pm Amanda Watkins, VMD, DACVS-LA, CiPD NIDCR T90 fellow – Poster Session Introduction
12:30 pm Lunch and Poster Presentation // Lerner Pavilion and Fonseca Garden
Poster Session Chairs: Zhi Ren, DMD, PhD and Zain Siddiqui, PhD Judges: Chider Chen, PhD, Pouria Fattahi, PhD, Kei Katsura, DMD, PhD, Eugene Ko, DDS, Claudia Loebel, PhD, Shravan Pradeep, PhD, Zain Siddiqui, PhD, Albane Thery, PhD, Marcelo Der Torossian Torres, PhD, Shujie Yang, PhD
12:30 pm CiPD Trainees and Fellow Meeting with Joseph M. DeSimone, PhD
CiPD FACULTY SPEAKERS AND TRAINEES LECTURES // William W.M. Cheung Auditorium
2:00 pm RESTORE Prize (Peter Quinn, DMD, MD and Eric Granquist, DMD, MD – Introduction) Ravi Radhakrishnan, PhD, Jina Ko, PhD and Kyle Vining, DDS, PhD – Precision Engineered Messengers: EV-LNP Hybrids for Cancer Therapy
2:30 pm Esra Sahingur, DDS, MS, PhD – Targeting the Inflammation–Senescence Axis in Periodontal Diseases: Mechanisms and Interventions
2:55 pm Kenvue // Coffee break and Collaborative Discussion Young Innovations
3:25 pm Dennis Sourvanos, DMD DScD – Beyond Pain Relief: Transforming Supportive Cancer Care with Precision Photobiomodulation Therapy for Oral Mucositis
3:40 pm Shefali Setia Verma, PhD and Flavia Teles, DDS, MS, DMSc – Predicting Periodontitis Progression: A Machine Learning Approach
4:05 pm Neocis
AFTERNOON PLENARY // William W.M. Cheung Auditorium
Bridging Oral Health & Systemic Wellness: Emerging Research & Future Innovations
4:10 pm Edward J. Zuckerberg, DDS, FAGD, CEO at Painless Social Media LLC/Venture Partner@Revere Partners/Chief Education Officer@Cloud Dentistry/Chief Dental Officer@Viome
5:15 pm CLOSING REMARKS AND RECEPTION // Lerner Pavilion and Fonseca Garden Zhi Ren, DMD, PhD, CiPD NIDCR R90 fellow | CiPD Colgate fellow
DREW WEISSMAN, MD, PhD
Drew Weissman, MD, PhD, is the Roberts Family Professor in Vaccine Research and Director of the Penn Institute for RNA Innovation at the Perelman School of Medicine. He is recognized for his work alongside Katalin Karikó in discovering the modified mRNA technology, which has launched a new era of vaccine and therapeutic development. Their mRNA research breakthrough has been used in both the BioNTech/Pfizer and Moderna COVID-19 vaccines and has revolutionized the field of vaccine development. Dr. Weissman’s current research focuses on developing a pancoronavirus vaccine to stop the next coronavirus epidemic, a universal flu vaccine, cancer therapeutics, a vaccine to prevent herpes, as well as developing in vivo gene therapy to allow worldwide use and a variety of protein therapeutics delivered with mRNA-LNPs. He has recently expanded his efforts in building scientific and medical equity and is developing the full RNA-LNP ecosystem of development, testing, and use in low and middle income countries.
Dr. Weissman earned bachelor’s and master’s degrees in biochemistry and enzymology from Brandeis University in 1981 and his M.D. and Ph.D. in immunology and microbiology in 1987 at Boston University School of Medicine. Following a residency at Beth Israel Hospital in Boston, he took a fellowship at the National Institutes of Health, where he worked with Dr. Anthony Fauci.
Dr. Weissman hold many patents and has published over 400 papers. He has been recognized with numerous awards including the Lasker-DeBakey Clinical Medical Research Award, the Breakthrough Prize in Life Sciences, the Albany Medical Center Prize in Medicine and Biomedical Research, and the Nobel Prize in Medicine or Physiology.
JOSEPH M. DESIMONE, PhD
Joseph M. DeSimone is the Sanjiv Sam Gambhir Professor of Translational Medicine and Chemical Engineering at Stanford University. He is also Co-Director of the Canary Center, Founding Faculty Director of the Center for STEMM Mentorship, and the Interim Vice Chair of Strategy in the Department of Radiology at Stanford. He holds primary appointments in Radiology and Chemical Engineering with courtesy appointments in Chemistry, Materials Science and Engineering, and the Graduate School of Business. Previously, DeSimone was a professor of chemistry at the University of North Carolina at Chapel Hill and of chemical engineering at North Carolina State University. He is also Cofounder, Board Member, and former CEO (2014 - 2019) of the additive manufacturing company, Carbon.
DeSimone is responsible for numerous breakthroughs in his career in areas including green chemistry, medical devices, nanomedicine, and 3D printing. He has published >390 scientific articles and holds >240 patents. In 2016 DeSimone was recognized by President Obama with the National Medal of Technology and Innovation. He is one of only 25 individuals elected to all three branches of the U.S. National Academies (Sciences, Medicine, Engineering). DeSimone received his B.S. in Chemistry from Ursinus College (1986) and Ph.D. in Chemistry from Virginia Tech (1990).
EDWARD J. ZUCKERBERG, DDS, FAGD
Edward J. Zuckerberg, D.D.S.,F.A.G.D. is a 1978 Graduate of NYU College of Dentistry. He owned his own practices in Brooklyn and Dobbs Ferry, NY from 1979-2013 and has always been an early adopter of technology, introducing his first PC in the office in 1986 and completely fully networking his home-based office with broadband access in 1996. Dr. Zuckerberg’s early adoption of technologies including digital radiography, CAD/CAM & creation of a paperless office caught the attention of Industry leaders who enlisted him to lecture, write articles and beta test new technologies. The advanced technology in the home helped launch his son, Mark’s, the founder of Facebook, interest in computers. With his wife of 45 years, Karen, a retired Psychiatrist, they also have 3 daughters, Randi, former Marketing Director at Facebook and now CEO of Zuckerberg Media, Donna, who received her Classics Ph.D at Princeton and is now an author & Arielle, who is a partner in a Financial Firm in San Francisco, as well as 10 grandchildren. Dr. Zuckerberg lectures nationally and internationally on the Oral Systemic Connection, serves as a Venture Partner at Revere Partners, the First Independent Venture Fund for Oral Health, acts as the Chief Dental Officer for Viome and the Chief Education Officer for both Cloud Dentistry & Oral BioLife in addition to treating patients part time in Cupertino, CA. Dr. Zuckerberg has co-authored several textbooks and is a frequent webinar and podcast guest as well as a regular contributor to Dental Journals.
Dr. Zuckerberg can be reached online at:
www.painlessdrz.com
www.facebook.com/painlesssocialmedia
https://www.linkedin.com/in/painlessdrz/
GENERAL SESSION
BARCELONA, SPAIN • JUNE 25-28, 2025
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