mRNA COVID-19 vaccine
1
2
Lipid nanoparticles
Lipid nanoparticles (LNP) in the vaccine deliver mRNA to cells
mRNA provides instructions for the cells to create the spike protein
mRNA
CELL Protein making machinery
3
The cell’s protein making machinery creates many copies of the spike protein
DNA 5
7
Immunity
The mRNA and spike protein are destroyed after their jobs are done Spike protein
Natural destruction
Antibody Production 6
T Cell 4
Interaction
Immune cells recognize the spike protein and interact with each other to mount an immune response
B Cell
Specific antibodies are made against the COVID-19 spike protein
ACTIVE SURVEILLANCE
You or your doctor report it!
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Health data is collected directly from vaccine recipients or their health care providers
PRO
•
More accurate
PRO
•
Rapid data collection
•
More expensive
CON
PASSIVE SURVEILLANCE
Anyone can report it!
Health data is collected indirectly from hospitals, clinics, public health units, and others (patients and/or their family members and caregivers)
•PRO Covers the wider population and whole communities •PRO Less expensive •CON Takes longer and can be less accurate