Antiaging aminoacids 2016

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AMINO ACIDS

Amino acids are at the basis of all life processes, as they are absolutely essen:al for every metabolic process.

Among their most important tasks are the: op:mal transport and op:mal storage of all nutrients (i.e. water, fat, carbohydrates, proteins, minerals and vitamins).

The majority of health issues such as obesity, highcholesterol levels, diabetes, insomnia, erec:le dysfunc:on or arthri:s can essen:ally be traced back to metabolic disturbances. This also applies to hair loss and serious cases of wrinkle forma:on.

This is why it is important to act sooner rather than later to ensure that the essen:al amino acids are available to the body in sufficient quan::es.

Unfortunately this cannot be guaranteed nowadays, due to the poor quality of our diet. This is why supplementa:on with amino acids is recommended.

On the following pages you can find a summary of various university studies on the posi:ve effects of amino acids on:

• An:-aging • Arthri:s and osteoporosis • Cholesterol • Diabetes • Fat-burning • Healthy skin • Hair loss • Menopause • Sleep, mood and performance • Virility

ANTI-AGING

Amino acids and their significance for An:-aging

Beau:ful skin, firm nails and shiny hair are certainly symbols for health and natural beauty. In order to keep them this way for as long as possible and to delay the aging process, a supply of certain nutrients is important. As the skin is a reflec:on of our metabolism, it is sensi:ve to any changes which may occur. Allergic reac:ons, infec:ons or poor circula:on and oxygen supply are quickly recognizable on the skin by a pale complexion, coarse-pores and sagginess.

The right amino acid mix acts like a repair treatment from within. This is confirmed by various studies which stress the importance amino acids have to keep the hair healthy and the skin firm.

Amino acids supply nutrients to nourish the skin, hair and nails from within the body. This procedure strengthens connec:ve :ssue and keeps the skin smooth and elas:c, the nails firm and the hair strong.

Crea:ne supports skin func:ons and s:mulates collagen produc:on

Crea:ne plays an important role for healthy skin. It is produced from the amino acids arginine and methionine, which are in turn a part of Carni:ne. Crea:ne is found naturally in the body and is par:cularly important for the energy metabolism of the cells. A person who weighs around 11 stone (70 kg) has around 120g of Crea:ne in their body, especially concentrated in the :ssue and cells with a high turnover of energy such as the muscles, brain or immune cells. The skin, which is the biggest organ, requires Crea:ne to carry out its func:ons effec:vely.

Crea:ne provides the cells with energy and thereby supports the regenera:on of connec:ve :ssue, cells and metabolism of the skin.

ANTI-AGING

As we age, cell division slows down and instead of every 28 days the cells are only renewed every 30 to 40 days (from age 40 onwards). This reduces the number of new cells which are needed for a youthful appearance. The number of suppor:ng fibers in the :ssue- collagen and elas:n – already begin to decrease from aged 25. The constant assembly and degrada:on processes are shiied away un:l more cells are broken down than are produced. UV rays, free radicals and aggressive oxygen compounds also damage the skin, resul:ng in the :ssue becoming weaker, the skin less elas:c and wrinkles forming.

The amino acids arginine and carni:ne form crea:ne

When the amino acids arginine and carni:ne form crea:ne, natural skin func:ons are supported and the cells are s:mulated to produce more collagen and elas:n.

Cells which are supplied with crea:ne are capable of repairing damaged DNA. Furthermore, crea:ne can protect the cells from harmful substances by surrounding them with a film of water. This allows the skin to replenish lost moisture. The importance of crea:ne for the forma:on of collagen is also prominent. This endogenous protein forms a fibre net, protects the connec:ve :ssue and is responsible for firm skin and strong ligaments, tendons and car:lage. Above all, collagen increases the ability to store water in the skin. Crea:ne s:mulates endogenous collagen produc:on. This allows the skin to connect more moisture, become thicker and have a smooth, fresh and wrinkle-free appearance.

Glutamine regulates the acid-base balance and firms the skin

ANTI-AGING

A balanced diet is a pre-condi:on for healthy skin. A supply of important nutrients slows down the aging process of the skin and supports the regenera:on of the cells. It is however oien the case that our diets are unbalanced or unhealthy. Coffee, nico:ne or excess meat consump:on can lead to hyperacidity. The acid-base is thrown off balance and cells and :ssues are destroyed. Amino acids can contribute significantly to a balanced acid-base balance, by neutralising the acids. Unfortunately, the availability of amino acids decreases with age and they are increasingly extracted from their own stores. Muscles and skin lose their elas:city, oien resul:ng in hair loss and wrinkles forming.

Glutamine is the deciding factor when trying to regulate the acid-base balance. This amino acid can drive off poisonous ammonia in the kidneys. A basic ammonia molecule combines a proton acid and is eliminated.

Through this, one acid is expelled from the body, while the bicarbonate is preserved, which is beneficial as it is needed for endogenous neutralisa:on of acids. Glutamine therefore supports the regula:on of the acid-base balance.

It is also important for firm skin.

Although glutamine can be produced by the body, it is not able to produce it in sufficient quan::es as we age. The consequences are alarming as the substance is responsible for the produc:on of protein. If there is not enough glutamine available, the body takes the necessary protein from the muscles and turns it into glutamine and energy.

This means that muscle protein gets lost, muscle strands become thinner and the skin loses its elas:city. The aging skin can be compared to a plant which withers and dries up. Glutamine can slow this process down, which is why scien:sts refer to it as the “fountain of youth from within”.

Carni:ne supports the transfer of fat to energy

The amount of fat in our bodies increases as we age. It is therefore important to do sport to keep fit. Carni:ne can also help with weight control as it improves the transport of famy acids as fuel to be burned off. This is why it is oien referred to as a “fatburner”. When combined with movement, carni:ne can contribute to an increased rate of fat burning. This is why it is an important aspect of fitness and wellness programs.7

ANTI-AGING

BIBLIOGRAPHY

1 Saini, R. & Zanwar, A. A. (2013) Arginine Derived Nitric Oxide: Key to Healthy Skin, Bioac:ve Dietary Factors and Plant Extracts in Dermatology (pp. 73-82)

2 Evangeliou, A. & Vlassopoulos, D. (2003) Carni:ne Metabolism and Deficit – When Supplementa:on is Necessary? Current Pharmaceu:cal Biotechnology, Volume 4, issue 3, (pp. 211-219)

3 Reda, E., D'Iddio, S., Nicolai, R., BenaN, P. & Calvani, M. (2003) The Carni:ne System and Body Composi:on Acta Diabetol, issue 40, (pp. 106-103)

4 Williams, J.Z., Abumrad, N. & Barbul, A. (2002) Effect of a Specialized Amino Acid Mixture on Human Collagen Deposi:on Annals of Surgery, Volume 236, issue 3, (pp.

369-375)

5 Welbourne, T.C. (1995) Increased plasma bicarbonate and growth hormone aier an oral glutamine load The American Journal Of Clinical Nutri:on, Volume 61, issue 5, (pp.

1058-1061)

6 Bowtell, J.L., Gelly, K., Jackman, M.L., Patel, A., Simeoni, M., Rennie, M.J. (1999) Effect of oral glutamine on whole body carbohydrate storage during recovery from exhaus:ve exercise Journal Of Applied Physiology, Volume 86, issue 6, (pp. 1770-1777)

7 Müller, D.M., Seim, H., Kiess, W., Löster, H. & Richter, T. (2002) Effects of Oral l-Carni:ne Supplementa:on on In Vivo Long-Chain Famy Acid Oxida:on in Healthy Adults Metabolism, Volume 51, issue 11, (pp. 1389-1391)

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