NC State Veterinary Medicine Genetic Testing

Small Animal

Genetic testing service

accurate, affordable and readily available Laboratory testing for genetic traits and diseases in dogs and cats is advancing rapidly.

At the NC State College of Veterinary Medicine, these detection services are available as an essential tool for veterinarians, breeders and owners of companion animals.

Currently the veterinary genetics testing service at the North Carolina State University College of Veterinary Medicine offers a range of DNA screening tests for cardiac and neurogenetic disorders that can occur in several specific canine and feline breeds.

DNA testing can be performed on blood samples (EDTA), buccal swabs or semen samples. Results, interpretations, and recommendations are provided by email. Genetic counseling is also available for follow-up.

Download sample submission forms at www.ncstatevets.org/genetics/submitdna or call 919.513.3314 for more information.

The following tests are now available:

Heart Disease in Dogs Boxer Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC or Boxer Cardiomyopathy) is an adult onset cardiomyopathy that can lead to sudden death or the development of congestive heart failure.

Doberman Pinscher Dilated Cardiomyopathy (DCM) is an adult onset disease that can lead to sudden death or the development of congestive heart failure.

Newfoundland Subvalvular Aortic Stenosis (SAS) is a cardiac birth defect characterized by fainting, rear limb weakness, or heart failure.

Canine Neurogenetic disorders Cerebellar degeneration in the Gordon Setter and Old English Sheepdog causes a progressive loss of coordination resulting in the hallmark ataxic gait characterized by dramatic overstepping, particularly obvious in the forelimbs. Onset of signs ranges from 6 months to 4 years of age.

Heart Disease in Cats Maine Coon and Ragdoll Hypertrophic Cardiomyopathy (HCM) is an adult onset disease that can lead to congestive heart failure and thromboembolic episodes.

Do you have questions about inherited diseases in your patients? Make an appointment to speak with a geneticist by e-mailing kate_meurs@ncsu.edu.

on-going research and care Extensive and detailed information about current studies being conducted at NC State College of Veterinary Medicine is available online:

www.ncstatevets.org/genetics Participants in clinical research studies may qualify for reduced rates on clinical evaluation. Please contact us or see website for further details.

Participating in the work

engaged in on-going

of the NC State College

research, partnerships

of Veterary Medicine

and collaborations

provides you access not

with industry and

only to the resources and

government researchers,

facilities at the Randall

entrepreneurs, clinical

B. Terry Companion

trial companies and to

Animal Veterinary Medical

world-class, state-of-

Center but also to faculty

the-art laboratories and

and students who are

equipment.

discovery and innovation are in our dna The Veterinary Genetics Laboratory is now administering research programs available for the following breeds and conditions:

Canine Cardiac disease Subvalvular Aortic Stenosis (SAS) Golden Retriever Newfoundland Rottweiler Cardiomyopathy studies Doberman Pinscher Great Dane Boxer

Canine Ocular disorders Corneal disease studies Boston Terrier: corneal endothelial dystrophy Boxer: indolent corneal ulcer (SCCEDs) Siberian Husky: crystalline corneal dystrophy

Canine Immune System disorders Immune-Mediated Hemolytic Anemia (IMHA) study Cocker Spaniel, Shih Tzu, and Maltese

Addison’s disease study Standard Poodle

Feline Cardiac disease Feline Hypertrophic Cardiomyopathy (HCM) study Bengal Birman Sphynx

1052 William Moore Drive Raleigh, NC 27607 919.513.6423 kate_meurs@ncsu.edu www.ncstatevets.org/genetics