Kineret Price in India.
Kineret: Availability in India
Pa$ents with moderately to highly ac$ve rheumatoid arthri$s who have received at least one disease-modifying an$rheuma$c medica$on (DMARD) but failed to manage signs and symptoms or delay the course of structural damage are prescribed kineret injec$on. These pa$ents must be 18 years of age or older. It is also used to treat Neonatal-Onset Mul$system Inflammatory Disease (NOMID). It is provided by Indian Pharma Network, and you may purchase it there at a fair price.
Kineret: Dosage and Administra6on
There is a 100 mg/0.67 mL subcutaneous injectable solu$on available. Doses between 20 and 100 mg are possible with a graduated syringe. Kineret is injected subcutaneously, or beneath the skin, to deliver the medica$on. Kineret 100 mg once daily is the recommended dosage for trea$ng rheumatoid arthri$s, and it should be taken roughly the same $me each day. The dosage for familial Mediterranean fever, S$ll's illness, and CAPS is based on the pa$ent's weight and the severity of the condi$on. Pa$ents with CAPS must be at least 8 months old and 10 kg in weight to receive treatment. Take 100 mg of COVID-19 once a day for 10 days.
Kineret: FDA Approved
Kineret was given the go-ahead to treat RA and Cryopyrin-Associated Periodic Syndromes (CAPS) on November 14, 2001. Human interleukin-1 receptor antagonist (IL-1Ra) is marketed as Kineret (anakinra) and is available in the recombinant, non-glycosylated form. A single methionine residue has been added to the amino terminus of Kineret, which makes it different from na$ve human IL-1Ra. Kineret has a molecular weight of 17.3 kilodaltons and 153 amino acids. It is created using a bacterial expression system from E. coli and recombinant DNA technologies.
Kineret: Storage
Glass single-use syringes with 27 gauge needles are used to administer Kineret. Each prefilled glass syringe has a 0.67 mL volume and weighs 100 milligrammes of anakinra. Anakinra is included in 100 milligrams of the whole syringe. A 4 x 7 syringe dispensing pack with 28 syringes is available to administer Kineret. One should store Kineret between 2 and 8 degrees Celsius or 36 and 46 degrees Fahrenheit. It must be protected from light, not torefrozen, or disturbed.
Kineret: Mechanism of Ac6on
Kineret (anakinra) is a recombinant, nonglycosylated form of the human interleukin-1 receptor antagonist (IL-1Ra). Immunosuppressive drugs work by reducing immune system func$on. An ar$ficial replica of a human protein called "human interleukin 1 receptor antagonist," anakinra blocks the body's interleukin 1 receptors. High levels of this interleukin produc$on are present in rheumatoid arthri$s pa$ents, which causes joint inflamma$on and, ul$mately, joint damage. Addi$onally, it fuels the inflamma$on connected to CAPS,
familial Mediterranean fever, and S$ll's illness. There is no binding site lec because anakinra prevents the ac$on of interleukin 1 by adaching to the receptors where interleukin 1 would ordinarily adach. The indica$ons and symptoms of many ailments are eventually relieved. Kineret injec$on is offered for a reasonable and cost-effec$ve price, and for more informa$on on Kineret cost, contact us at Indian Pharma Network | +91 93100 90915(TollFree).
Kineret: Adverse Reac6ons
• Rheumatoid Arthri$s (RA) The most frequent side effects (incidence 5%) are injec$on site reac$ons, rheumatoid arthri$s aggrava$on, upper respiratory tract infec$ons, headaches, nausea, diarrhea, sinusi$s, arthralgia, and stomach discomfort.
• NOMID- The most frequently reported adverse effects (incidence >10%) during the first six months of treatment were injec$on site reac$ons, headaches, vomi$ng, arthralgia, pyrexia, and nasopharyngi$s.
• Only with a prescrip$on can one receive Kineret, and only a licensed physician should ini$ate and oversee treatment. The kineret injec$on is available fairly and cheaply
Kineret: Drug Interac6on
There have been no studies on medica$on interac$ons involving humans. The clearance or toxicologic profiles of either drug did not significantly change acer methotrexate and Kineret administra$on to rats in toxicologic and toxicokine$c studies.
• TNF Blocking Agents: Studies have shown that pa$ents taking concurrent Kineret and etanercept therapy have a greater incidence of serious infec$ons than pa$ents gelng etanercept alone. In 2% of individuals receiving Kineret and etanercept simultaneously, neutropenia (ANC 1 x 109/L) developed. Combining Kineret with TNF-blocking drugs is not recommended.
• Kineret can only be obtained with a prescrip$on; only a qualified medical professional should start and manage treatment. The cost of Kineret injec$on is reasonable and accessible; for addi$onal details,
Kineret: Use In Specific Popula6on
• When a young person has NOMID, Kineret is advised for geriatric use. Due to the higher prevalence of infec$ons in the senior popula$on as a whole, care should be taken when trea$ng the elderly.
• Renal dysfunc$on: Because this medica$on is believed to be mostly removed through the kidneys, pa$ents with impaired renal func$on may be more vulnerable to nega$ve drug responses.
• Kineret should only be used under the supervision of a licensed medical professional, and a prescrip$on is required to obtain it.
Kineret: Warnings and Precau6ons
• Stop using the RA medica$on if a serious infec$on develops. Pa$ents with NOMID should weigh the poten$al risks of quilng Kineret therapy against the possibility of a NOMID flare. Star$ng Kineret shouldn't be done by pa$ents who have ac$ve infec$ons.
• Combining it with drugs that block tumor necrosis factor (TNF) is not recommended.
• There have been documented cases of angioedema and anaphylac$c reac$ons, among other hypersensi$vity events.
• Kineret treatment has not been demonstrated to affect the development of cancer or ac$ve or persistent infec$ons.
• Live vaccines shouldn't be given combined with Kineret.
• Before beginning Kineret therapy, neutrophil levels should be assessed every three months while on Kineret and then every six months for up to a year acerwards.
• Kineret injec$on is priced fairly and ra$onally; for more informa$on on the medica$on and Kineret 100 mg/0.67ml
Source - hdps://helpforheallth.blogspot.com/2023/05/kineret-for-rheumatoid-arthri$s.html
