2025 Moffitt Scientific Symposium

Page 1


PROGRAM AGENDA

Day 1 – Monday, May 12th, 2025

SRB Ted Couch Auditorium

4:00-5:00 PM Moffitt Researcher of the Year lecture: Frederick Locke, MD

5:00-6:00 PM Reception in SRB Atrium

Day 2 – Tuesday, May 13th, 2025

USF Marshall Student Center

8:00-9:00 AM Registration, Breakfast & Poster Viewing in the Ballroom

9:00-9:10 AM Welcome, Dr. Patrick Hwu, President, and CEO (Oval Theater)

9:10-9:50 AM Featured Poster Presentations - Session I (Oval Theater)

Moderator: Dr. Heather Owens

Rojan Chimeh Rad (Gomes) “Aging drives TNBC lung metastasis dependency on FGFR-triggered metabolic reprogramming exposing an age-induced liability with therapeutic potential”

Dr. Paige Aiello (Lee) “The Significance of Micrometastatic Axillary Disease after Neoadjuvant Chemotherapy in Breast Cancer”

Dr. Evan Davis (Permuth) “Applying Large Language Models for Clinical Data Abstraction in Patients with Pancreatic Tumors”

Dr. M A Masud (Anderson) “The role of tissue homeostasis in regulating basal cell carcinoma growth dynamics”

Dr. Jeremy Frieling (Lynch) “Defining immune – stromal cell crosstalk during γδ CAR-T targeting of bone metastatic prostate tumors”

Dr. Michelle Dugan (Zager) “A Comparison of Isolated Limb Infusion/Perfusion, Immune Checkpoint Inhibitors, and Intralesional Therapy as First-Line Treatment for Patients with Melanoma In-Transit Metastases”

Dr. Charles Hoogland (D. Vidrine, J. Vidrine) “Baseline Sociodemographic, Smoking-Related, and Psychosocial Characteristics of Participants Recruited In-person vs. Online to a Smoking Cessation RCT Targeting People with Food Insecurity”

Dr. Larissa Carvalho (K. Smalley “Defining the anti-tumor activity and immune affects of the RASMULTI(ON) inhibitor RMC-7977 in preclinical models of NRAS-mutant melanoma”

9:50-10:25 AM Featured Poster Presentations - Session II (Oval Theater)

Moderator: Dr. Mitchell Hayes

Dr. Victor Gazivoda (Pimiento) “Prophylactic Robotic Assisted Total Gastrectomy is a safe practice in patients with hereditary diffuse gastric cancer ”

Dr. Thales Nepomuceno (Monteiro) “CDK9 promotes DNA repair independently of its role in transcription”

Dr. Paulo Cilas Morais Lyra Junior (Goecks) “Optimizing Cancer Analyses with Best-Practices Machine Learning: A Web Application”

Dr. Mariam Khaled (I. Smalley) “Multiomic analyses revealed disruptive immune and metabolic microenvironment in leptomeningeal disease”

Dr. Jeffrey Johnson (Chahoud) “Updated Efficacy, Safety, and Correlative Analysis of a Phase II Trial in Metastatic Renal Cell Carcinoma with Short Course Pembrolizumab and High Dose IL-2”

Dr. Xiaonan Xu (Karreth) “Novel mouse models recapitulate human uveal melanoma” Sabeen Ahmed (Rasool) “Multimodal AI for Accurate Prediction of Cancer Cachexia”

10:30-11:30 AM Poster Session #1 (Ballroom) Odd Numbered Posters

11:00- 12:00 PM Lunch (Ballroom)

11:30-12:30 PM Poster Session #2 (Ballroom) Even Numbered Posters

12:30-1:20 PM Oral Presentations – Session I (Oval Theater)

Moderator: Dr. Daniel Antfolk

Dr. Oyedolapo Anyawu (Gwede) “Baseline Data and Protocol for a Multibehavioral, Multilevel Intervention to Promote Concurrent Colorectal Cancer and Hepatitis C Screening Uptake among Patients Aged 45-75”

Dr. Jianan Chen (Etame) “Integrative Transcriptomic and Single-Cell Analysis Reveals RNF135 as a Prognostic and Immunological Biomarker in Glioblastoma”

Dr. Karla Feliciano Salva (Hansen) “Impact of Plasma Cell Burden (PCB) on Response and Survival in Relapsed/Refractory Multiple Myeloma (RRMM) Patients Receiving Standard of Care

Idecabtagene Vicleucel (ide-cel)”

Dr. Daniel Glazar (Brady-Nicholls) “Patient-reported symptoms correlate with early progression in non-small cell lung cancer treated with immune checkpoint inhibitors”

Dr. Felicia Lazure (Gomes) “Aging drives the differential evolution of KRAS-driven lung adenocarcinoma towards a primitive stem-like state”

1:20-2:10 PM Oral Presentations – Session II (Oval Theater)

Moderator: Dr. Emily Keit

Sarah Lulu (Hwu) “Intratumoral treatment of glioblastoma (GBM) with chimeric antigen receptor (CAR)T-cells expressing membrane-bound CD40L and activated by TLR agonism increases survival in syngeneic CT2A mouse model”

Olabisi Osunmakinde (Ruffell) “Investigating cholesterol transfer between macrophages and prostate cancer cells”

Dr. Samantha Seitter (Sinnamon) “Routine Staging Laparoscopy Prior to Neoadjuvant Therapy for Pancreatic Cancer Yields Significant Rate of Occult Metastatic Disease”

Dr. Shahrzad Zamani (Schabath) “Analysis of sexual orientation and gender identity (SOGI) data reveals real-world cancer disparities among sexual and gender minorities (SGM) at the Moffitt Cancer Center”

Dr. Md Muntasir Zitu (Rollison) “Large Language Models for Cancer Registry Coding Using RealWorld Moffitt Patient Data: Performance Evaluation and Error Analysis”

2:10-2:20 PM Patient Experience, Mary Margaret Braddock (Oval Theater)

2:20-2:30 PM Best Poster Awards and Postdoc Poster Winner Announcement (Oval Theater)

TRANSPORTATION

A Moffitt shuttle bus will be running a continuous route between Moffitt and the USF Marshall Center on Tuesday, May 13th from 7:30AM-3:00PM. You may also choose to walk or drive your personal vehicle if you have an appropriate USF parking permit.

Please see map below for exact shuttle stop locations.

Moderators and Oral/Featured Presenters will be provided with reserved parking in the Crescent Hall Parking Garage.

Shuttle stop =

MOFFITT SCIENTIFIC SYMPOSIUM

FREQUENTLY ASKED QUESTIONS (FAQ)

1. Where is the Symposium located?

Monday, May 12th, 2025 - the Moffitt Researcher of the Year lecture will take place in the Stabile Research Building (SRB) Ted Couch Auditorium followed by a reception in the SRB Atrium.

Tuesday, May 13th, 2025 - all activities will be at the USF Marshall Student Center.

2. How can I get to the Marshall Center? Is there parking?

Reserved parking has been set aside for featured posters, oral presenters, committee members and speakers only. General attendees should walk to the Marshall Center or take the Moffitt shuttle which will be continuously running between Moffitt and the Marshall Center. Please review the transportation page in this guide for shuttle locations and times.

3. How do I know what poster session I can find certain presenters?

This guidebook shows the poster number for every presenter. The poster sessions are divided up by odd numbered posters (poster session #1) and even numbered posters (poster session #2).

4. Is there Wi-Fi available at the Symposium?

Wireless access is provided to guests of USF. Please follow these directions:

1.) Open your list of wireless connections on your device and select “USF-Guest”

2.) Once you are connected, open your web browser and attempt to navigate to a website. You will automatically be redirected to the Guest Registration page

3.) On this page, select your preferred method of contact. Either “call me on my phone” or “send me a text message”

4.) You will receive a temporary access code within 5 minutes. Select the option “I have my access code”. You will need to agree to the acceptable use policy to continue

5.) Enter your mobile phone number and the registration code you received and hit “submit”

6.) You are now connected to the USF-Guest network. The registration will last for 24 hours and is valid for 1 device.

FEATURED POSTERS

Presenter Title (mentor)

Chimeh, Rojan Aging drives TNBC lung metastasis dependency on FGFR-triggered metabolic reprogramming exposing an age-induced liability with therapeutic potential (Gomes)

Aiello, Paige The Significance of Micrometastatic Axillary Disease after Neoadjuvant Chemotherapy in Breast Cancer (Lee)

Davis, Evan Applying Large Language Models for Clinical Data Abstraction in Patients with Pancreatic Tumors (Permuth)

Masud, M A The role of tissue homeostasis in regulating basal cell carcinoma growth dynamics (Anderson)

Frieling, Jeremy Defining immune – stromal cell crosstalk during γδ CAR-T targeting of bone metastatic prostate tumors (Lynch)

Dugan, Michelle A Comparison of Isolated Limb Infusion/Perfusion, Immune Checkpoint Inhibitors, and Intralesional Therapy as First-Line Treatment for Patients with Melanoma In-Transit Metastases (Zager)

Hoogland, Charles Baseline Sociodemographic, Smoking-Related, and Psychosocial Characteristics of Participants Recruited In-person vs. Online to a Smoking Cessation RCT Targeting People with Food Insecurity (D. Vidrine, J. Vidrine)

Carvalho, Larissa Defining the anti-tumor activity and immune affects of the RASMULTI(ON) inhibitor RMC-7977 in preclinical models of NRAS-mutant melanoma (K. Smalley)

Gazivoda, Victor Prophylactic Robotic Assisted Total Gastrectomy is a safe practice in patients with hereditary diffuse gastric cancer (Pimiento)

Nepomuceno, Thales CDK9 promotes DNA repair independently of its role in transcription (Monteiro)

Morais Lyra Junior, Paulo Cilas

Optimizing Cancer Analyses with Best-Practices Machine Learning: A Web Application (Goecks)

Khaled, Mariam Multiomic analyses revealed disruptive immune and metabolic microenvironment in leptomeningeal disease (I. Smalley)

Johnson, Jeffrey Updated Efficacy, Safety, and Correlative Analysis of a Phase II Trial in Metastatic Renal Cell Carcinoma with Short Course Pembrolizumab and High Dose IL-2 (Chahoud)

Xu, Xiaonan Novel mouse models recapitulate human uveal melanoma (Karreth) 014

Ahmed, Sabeen Multimodal AI for Accurate Prediction of Cancer Cachexia (Rasool) 015

BASIC SCIENCE POSTERS

Listed alphabetically by last name

Presenter

Acevedo Acevedo, Suehelay

Title (mentor)

Metabolic reprogramming in 3D ex-vivo lung adenocarcinoma cancer models (Flores)

Ackerman, Hayley TAp73 expression in the tumor microenvironment mediates antitumor immunity via regulation of lipid metabolism (Flores)

Adhikary, Santanu

Beato, Francisca

Bhattacherjee, Debojit

Bishop, Ryan

Bjornberg, Alicia

Boucher, Justin

Brunel, Alexia

Caumont, Virgile

Changizi, Shirin

Chao, Ting

Delta Np63/YAP regulates resistance to KRAS inhibitor via modulating tissue stiffness and metabolic alterations in lung adenocarcinoma (Flores)

An Organoid Based T-Cell Cytotoxicity & Potency Assay (Permuth)

Harnessing High-Throughput Chemical Proteomics for Tumor-Specific Target Discovery Using Fragment-Based Approaches (Rix)

Spatial transcriptomic profiling of the immune landscape in multiple myeloma (Lynch)

Cellular plasticity facilitates therapy resistance through enhancing adaptability (Marusyk)

CAR T cells lacking CD3zeta can eliminate B cell lymphoma using NKG2D signaling (Guevara)

TSPAN1/8-Dependent Mechanisms Maintain Dormancy and Therapy Resistance in Disseminated Breast Cancer Cells (Oskarsson)

Non-cell autonomous interactions enhance plasticity-mediated therapy adaptation of lung adenocarcinoma cells (Marusyk)

A Novel Photopolymerization Approach for Cellular Backpack Engineering in Immunotherapy (Dunne)

Fragment probe library-based ligand screen for the identification of small molecules that decrease NRF2 activity (Jiang)

Chen, Harry Mechanisms of CMG Helicase Inhibition by the Retinoblastoma Protein Involve Direct CMG Binding and Potential Control of ATP Hydrolysis (Alexandrow)

Choudhury, Feroza

Craig, Kendall

Deshpande, Avani

Drapela, Stanislav

Dumbali, Sandeep

Emmons, Michael

Fernandes, Vanessa

Fidudusola, Fidara

Galaktionova, Daria

Tracing NRF2 dependent spatial metabolism during lung tumorigenesis (DeNicola)

Synthesis of Novel CMG Helicase Inhibitors (CMGi) for Treatment of K-Ras-Driven Tumors (Alexandrow, N. Lawrence) 204

Investigation of a novel lncRNA, TROLL-9, in breast cancer formation and progression (Flores) 036

Microenvironment driven dynamic deposition of histone H3.3 controls entry and exit from dormancy in disseminated cancer cells (Gomes) 035

Examining NNT’s Pleiotropic Regulation of Lung Cancer Mitochondria (Ward) 098

Stress-induced HDAC8 reprogramming drives IL-11-mediated immune escape in melanoma (K. Smalley) 099

Identification of new targets in small cell lung cancer using chemoproteomic-enabled fragment-based drug discovery (Rix) 154

Therapeutic Potential of Solasodine in the Management of TripleNegative Breast Cancer (Solima) 101

Unactivated Photoredox C–H Amination with Diazirine (Lopchuk) 172

Gangadharan, Achintyan ALK1 as a regulatory of dendritic cell function (Ruffell) 122

Georgei, Maria

Hasan, Hasanain

Hernandez, Diego

Huang, Yun

Humphrey, Briley

Ibrahim, Mohammed

Ilter, Didem

Islam, Shamima

Joseph, Manica

Karanam, Laxmi Swetha

Kashfi, Hossein

Kaur, Prerneet

Kim, Yumi

Knight, Andrew

Krueger, Katharine

Kumar, Pragya

Mitochondrial Regulation of the Cytosolic Redox State Potentiates Ferroptosis (Ward)

Non-invasive follicular thyroid neoplasms with TERT or TP53 mutations (Hernandez Prera)

Impact of Translucent Sheet Bolus and Melanin Concentration on Recorded Optical Signal During Cherenkov Imaging in External Beam Radiation Therapy (Andreozzi)

110

CRISPR screens identify GSR as a vulnerability for KEAP1/NRF2 mutant NSCLC (Jiang) 167

Design and Synthesis of Small Molecule Inhibitors of ULK3 for Multiple Myeloma (N. Lawrence) 140

Suppression of TNFα and IFNγ signaling are key molecular events in KRASG12C mutant cancer cells to confer therapeutic resistance to Sotorasib and promote immune evasion (Beg)

Ferroptosis is a metabolic vulnerability of dormant disseminated breast cancer cells (Gomes)

The E3 ubiquitin ligase Hectd3 controls immune colonic inflammation by restricting Myd88 signaling (Avram)

Diabetes Mellitus Prevalence, Management, and Outcomes (Yedjou) 023

Role of collagen I in the metabolic stress induced cancer cell dormancy and stemness (Nguyen)

Quinolinic acid phosphoribosyl transferase (QPRT) expression is an essential liability of non-small cell lung cancer independently of its enzymatic function (Gomes)

Metabolic shifts and Pathway alterations following Targeted AlphaParticle Therapy in Uveal Melanoma cells (Morse)

PHGDH Supports Glutamine Levels and Promotes PDAC Progression (DeNicola)

Chronic Glucocorticoid Exposure Protects Non-Small Cell Lung Cancer from Ferroptosis (Gomes)

Mechanistic insights into RBFOX2-mediated alternative splicing events in pancreatic cancer progression and metastasis (Mann) 187

Accelerated drug metabolism as a bona fide resistance mechanism to targeted therapies (Marusyk) 182

Lester, Daniel Investigating the Lung Tumor Microenvironment in the naked mole rat (Kissil)

Li, Jie

Lui, Ashley

Martin, Ryan

Miner, Robert

Miranda, Kaitlyn

Napoli, Marco

Nguyen, Loc

The ectonucleotidase ENPP1 inhibits STING activation and anti-tumor immunity in BRCA-deficient breast cancer (Ruffell)

RNA-Based Therapeutics to target the p53 pathway in high-grade serous ovarian cancer: TAp63-Regulated Oncogenic LncRNAs (TROLLs) as a novel therapeutic targets (Flores)

Investigation of KEAP1-Independent Mechanisms of NRF2 Degradation in Non-Small Cell Lung Cancer (Jiang)

Development of a novel, non-BCMA targeting CAR-T cell therapy for the treatment of multiple myeloma (Binning)

Identifying therapeutic targets of delta Np63 driven metabolic reprogramming in Lung Squamous Cell Carcinoma (Flores)

RNA-based therapeutics to target the p53 pathway in cancer (Flores) 026

Actinium-225 targeted alpha-particle therapy causes cell-cycle DNA damage checkpoint arrest and programmed cell death in MC1R expressing uveal melanoma (Morse)

Yilmaz, Anyur Sanem
(Dunne)

CLINICAL SCIENCE POSTERS

Listed alphabetically by last name

Presenter

Aboujaoude, Michael

Alzarkali, Omar

Ammad Ud Din, Mohammad

Amofa-Ho, Sam

Arfa, Ahmed

Avasthi, Kapil

Barnes, Anna

Baumrucker, Camille

Title (mentor)

Relatlimab and Nivolumab with and without Radiation Therapy in the Management of Melanoma Brain Metastases (Ahmed)

Progression-Free Survival and Overall Survival in Relapsed/Refractory T-cell Lymphoma patients on Chemotherapy vs Targeted Therapy (Saeed)

The Real-World Safety and Tolerability of Pirtobrutinib among Patients with B cell lymphomas; a Single Center Experience (PinillaIbarz)

Correlation between liver lesion biopsy cytopathology and histopathology reports – a retrospective review (Centeno)

Complex Karyotype does not Worsen Survival in MDS/AML with inv(3)/t(3;3) (Hussaini)

Development of a Multiplex PCR and NGS-Based Method for Detecting Cancer-Specific Splice Variants in Clear Cell Renal Cell Carcinoma (Wang)

Comparison of Open and Percutaneous Instrumented Fixation for the Treatment of Spinal Metastases (Liu)

Outcomes after Intratumoral Delivery of Immunotherapy in Breast Cancer (Lee)

Behne Sharma, Alexis Incidence and Outcome of Pulmonary Hypertension in Myelofibrosis (Lee)

Boozo, Mohammad Baraa A retrospective analysis of the incidence, clinical characteristics and outcomes of leptomeningeal disease in patients with metastatic melanoma (I. Smalley)

Cano, Carlos

Childers, Betzaira

Chiodo, Celina

Improvement of Diagnostic Accuracy in Breast Pathology, our Experience with Subspecialty Consensus Conference at a Cancer Center (Harper)

An Evidence-Based Paradigm for Intraoperative Carcinoid Crisis Management: No Prophylaxis and a Bundle Treatment Protocol Improves Operative and Clinical Outcomes - A Single center experience with over 500 surgical cases (Anaya)

Multi-institutional outcomes following chemotherapy, surgery, and locoregional and metastasis-directed radiation therapy for de novo oligometastatic breast cancer (Mills)

Dave, Apeksha "Missed" Rectal Organ Preservation with Pathologic Complete Response following Total Neoadjuvant Treatment: Why did they undergo mesorectal excision? (Felder)

Donovan, Eileen

Elzaafarany, Osama

Hammami, M Bakri

Haney, Sean

Role of Intraoperative Ablation in Patients Undergoing CurativeIntent Resection for Colorectal Liver Metastases (Denbo)

Decoding NF2: Clinical and Genetic Insights from a Rare Disease Cohort (Moktari)

Evaluating CAR-T cell therapy response in patients with Richter’s Transformation (Locke)

Predictors of Survival Outcomes of Allogeneic Transplantation in Elderly Patients with Acute Myeloid Leukemia and Myelodysplastic Syndrome (Bejanyan)

Rice, Komal

Selvakumar, Sruthi

Shahzad, Moazzam

Shannon, Adrienne

Strong, Erin

Tepper, Sarah

Trivedi, Purvish

Tuz Zahra, Fatima

Whiting, Junmin

Wright, Corbin

Wu, Qiong

Zervoudakis, Guston

Zhao, Dekuang

Zhou, Zoe

Image-guided SmartClip Localization for Breast and Axillary Lesions: Placement and Outcomes Evaluation (Weinfurtner)

Incidence of Major Adverse Cardiovascular Events with Venetoclax-based Therapy in Newly Diagnosed Acute Myeloid Leukemia (Lee)

Outcomes of Neoadjuvant Therapy in Advanced Melanoma: A Systematic Review and Meta-Analysis (Jaglal)

Survival Outcomes of Acral Lentiginous Melanoma in the Era of Modern Immune Checkpoint Inhibitor and Targeted Therapy (Perez)

Patients Seeking Second Opinions at an NCI-Designated Comprehensive Cancer Center: A Population Segment with Unique Needs and Preferences (Anaya)

Factors Related to Aseptic Loosening in Endoprosthetic Reconstruction of the Proximal Tibia (Lazarides)

Novel voxel-based MRI risk score LADCT2 as a tool for prediction of prostate cancer (Yamoah)

Real World Outcomes of Oral Azacitidine Maintenance Therapy forAcute Myeloid Leukemia: A Single Center Experience (Chan)

Adverse event as informative biomarker in predicting clinical outcomes in colorectal cancer patient treated with immunotherapy (DT. Chen)

Outcomes of patients with concurrent chronic lymphocytic leukemia and non-small cell lung carcinoma (Shafique)

The reprogramming impact of SMAC-mimetic on glioblastoma stem cells and the immune tumor microenvironment evolution (Etame)

Outcomes of Breast Cancer Metastases to the Appendicular Skeleton in the Setting of Current Treatment Modalities (Lazarides)

Early Detection of Metastatic Progression by Circulating Tumor DNA in Patients Undergoing Bladder-preserving Trimodality Therapy (Grass)

A Novel Patient-Derived 3D Microtumors Platform for Therapeutic Prediction in Ovarian Cancer (Sawyer, George)

POPULATION SCIENCE POSTERS

Listed alphabetically by last name

Presenter

Adamus, Isabel

Amorrortu, Rossybelle

Antoine, Kiana

Basinski, Toni

Berroa, Johnathan

Boxtha, Carol

Brockway, Samuel

Garcia, Melany

Gebert, Ryan

Title (mentor)

Developing Literacy-Friendly Cancer Education Handouts for Hispanic/Latino Community Members: A Collaborative Approach (Christy)

User-Centered Design of digital tools to enhance referral and enrollment of minority patients to cancer clinical trials (Vadaparampil)

A feeding study examining the effects of diet-specific interventions on the gut microbiome (Carson)

Development of an Educational Curriculum for Primary Care Providers Who Serve as the First Line of Defense Against Pancreatic Cancer in Underserved Communities (Permuth)

An Iterative Approach to Updating an Educational Booklet to Promote Colorectal Cancer Screening and Hepatitis C Virus Screening (Gwede)

My Portal CARES Interviews of Electronic Patient Portals Utilization Among Rural and Urban Setting Federally Qualified Health Centers (FQHC) in Central Florida (Meade)

Baseline Sociodemographic, Smoking-Related, and Psychosocial Characteristics of Participants with Low vs. High Food Insecurity Enrolled in a Smoking Cessation RCT (D. Vidrine)

Using the Socioecological Model for Formative Research to Develop and Refine Community Outreach and Digital Interventions to Enhance Diversity in Clinical Trials (Rollison)

A Questionnaire-Based Cross-Sectional Survey of Cancer Patients and Healthy Participants in the Ponce Health Region of Puerto Rico (Cress)

Geiss, Carley Assessing feasibility, appropriateness, and acceptability of digital patient journaling for qualitative data collection (Gonzalez)

Hernandez, Delilah

Jones, Sarah

Lake, Paige

Matos, Madison

Preliminary use of an interactive decision aid educating patients about cancer clinical trials (Vadaparampil, Rollison)

Associations between Wellness Plan Utilization, Treatment Engagement, and Smoking Abstinence: Secondary Analysis of an RCT Among Women with a History of Cervical Cancer (J. Vidrine)

Application of a patient-centered communication (PCC) model in AYA cancer care: Exploring AYA patient and clinician perspectives on PCC and its role in addressing patient psychosocial well-being, fertility, and decision-making (Vadaparampil)

Examining Organizational Capacity Pre/Post Implementation of Evidence-Based Interventions to Increase Adolescent Human Papillomavirus (HPV) Vaccination: Preliminary Results from the HPV MISTICS Trial (Vadaparampil)

QUANTITATIVE SCIENCE POSTERS

Listed alphabetically by last name

Presenter Title (mentor)

Abudalou, Shatha

Altinok, Oya

Training Challenges of deep networks across readers in delineating Prostate gland anatomy (Balagurunathan)

Radiomics with super-voxel segmentation improves HPV prediction accuracy significantly in oropharyngeal cancer (Schabath)

Anderson, Hannah Developing a virtual murine cohort for adoptive cell therapy in bladder cancer (Rejniak)

Barnett, Ari

Moment Informed Radiotherapy (West)

Barrios Ginart, Jorge A Question-Based Approach for Eligibility Representation in a PatientTrial Matching Chat Application (Eschrich)

Bhattacharya, Ranjini

Cao, Biwei

Carrasquilla, Alejandro

Resource Sharing Dynamics Shape Cancer Cell Foraging Strategies (Brown)

B-STAR: Unifying Moffitt Research through a Centralized Tool Repository (Reich)

Utilizing Machine Learning Models to Guide and Optimize Clinical Management of Cancer-Associated Compression Fractures (Tran)

Conahan, Piyawan Using Explainable AI to Identify Key County-Level Factors for the Reduction of Blacks’ and Whites’ Late-Stage Lung Cancer Diagnosis and its associated disparities (Luo)

Duong, Thac

Investigating ECM alternative splicing in solid tumors (Shaw)

Forero Pinto, Ana In silico modeling of cell-stroma mechanical interactions in DCIS progression (Rejniak)

Froid, Matthew

Gallaher, Jill

Gatenbee, Chandler

Hartsock, Iryna

Havor, Phebe

Koutsoubis, Nikolas

Kumar, Rikhil

Li, Tao

Makower, Gabriel

Marzban, Sadegh

Mizgalska, Katarzyna

Murthy, Amith

An Agent-Based Model of the Multiple Myeloma TME Provides Insights into TCE Resistance (Basanta)

Identifying early progressors of adaptive therapy in metastatic castrate-sensitive prostate cancer (Anderson)

Synergy between CAR T and the endogenous immune system is key to a complete response in large B cell lymphoma (Anderson)

Improving Radiology Report Conciseness and Structure via Locally Run Large Language Models (Rasool)

Circulating tumor DNA Dynamics as a Leading Indicating Biomarker for Time to Progression in HPV-associated Anal Squamous Cell Carcinoma (Brady-Nicholls)

Harnessing Distributed Intelligence with Privacy Preservation: Federated Learning for the Early Detection of Lung Cancer (Rasool)

Applying Shifted-Window Transformer Backbones to Cell Segmentation of Microscopy Images (El Naqa)

A Tick-Tock model of tumor growth (Andor)

A Multimodal AI Pipeline for BI-RADS Prediction: Addressing Bias and Class Imbalance in Breast Cancer Diagnosis (El Naqa)

Mechanistic learning reveals stem cell state transitions as biomarkers for disease progression and therapy response in BCP-ALL (West)

Mutations in drug binding sites: integrating computational chemistry and machine learning to understand mutation-induced resistance (Karolak)

CLEAR-MATCH: Patient-centered, AI-powered clinical trial matching (Eschrich)

Murugappan, Vishwa

Obermayer, Alyssa

Paz, Sheimy

Prabhakaran, Sandhya

Pybus, Alyssa

Qi, Yunli

Qiu, Junhao

Scibilia, Kevin Robert

Thompson, Zachery

Tripathi, Aakash

Upadhyaya, Diya

Venkatesan, Kavya

Waqas, Asim

Xella, Agata

Molecular Characterization of Radiation Response Patterns Across Cancer Cell Lines (Shaw)

Developing ShinyEvents: a generalizable framework for the analysis of longitudinal molecular and clinical data (Shaw)

Incidence of DVT/PE in cancer patients undergoing endoscopy with general anesthesia: Leveraging ICD-Codes for data-efficient supervised fine-tuning of Transformers (El Naqa)

Evolutionary immunotherapy in NSCLC: identifying optimal dosing strategies in TIL therapy using agent-based modeling (Anderson)

Predicting patient response to immune checkpoint blockade therapy in multiple cancers using real-world clinical data and machine learning (Goecks)

Learning Optimal Adaptive Therapies in Space and Time: Dynamic Threshold Therapy (Anderson)

Accelerating Cancer Research with AI-Powered Software Agents (Goecks)

Evolutionary therapy for metabolically heterogeneous tumors: The critical role of an acid-driven public bad (Anderson)

An R Shiny Application for Analysis of Adverse Events and their Association with Clinical Outcomes in Clinical Trials (DT. Chen)

HoneyBee: A Modular Framework for Embedding Multimodal Oncology Data (Rasool)

Leveraging Patient-Reported Outcomes with Mathematical Modeling to Predict Tumor Volume Dynamics (Brady-Nicholls)

Safety and Reliability of Large Language Models (LLMs) for Cancer Survivors - Preliminary Results (Rasool)

Exploring Reasoning Capabilities of Large Language Models (LLMs) in Pathology (Schabath)

‘Go or grow’ phenotypic drift in an agent-based model of EpithelialTo-Mesenchymal Transformation (Anderson)

Wang, Chao

Wong, Jodie

Adoptive cell therapy using tumor infiltrating lymphocytes induces impairment of tumor-infiltrating B cells in patient research biopsies (Creelan)

138

Plasma cell-free DNA methylation-based prognosis in metastatic castrate-resistant prostate cancer progression (Wang) 116

2025 MOFFITT SCIENTIFIC

SYMPOSIUM COMMITTEE

Dr. Inna Smalley (Co-Chair)

Dr. Evan Wuthrick (Co-Chair)

Dr Yoga Balagurunathan

Dr. Leidy Isenalumhe

Dr. Zena Jameel

Dr. Matthew Mills

Dr. John Mullinax

Dr. Thordur Oskarsson

Dr. Ranjita Poudel

Dr. Gage Redler

Dr. Katarzyna Rejniak

Dr. Michael Shafique

Dr. Moazzam Shahzad

Dr. Vani Simmons

Dr. Erin Strong

Dr. Lixin Wan

Dr. Liang Wang

EVENT COORDINATORS

Jill Fraley

Angela Reagan

Sarah Riordan

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