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ParaStruct

Cell-Free Systems for Sustainability

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The Problem

The bioeconomy has great potential to reduce our reliance on petrochemicals, but it faces a scalability challenge. Many companies have tried to scale fermentation for sustainable chemical production. But fermentation often falls short because of low-yields, product toxicity constraints, and costs that far exceed that of petroleum products. Without a scalable solution to address these issues, the bioeconomy will not be able to effectively mitigate the impact of climate change.

The Solution

Caravel is developing a cost-effective, cell-free technology platform to produce products in areas where fermentation falls short. We use enzymes – just like in fermentation – to quickly catalyze specific chemical transformations. But we only use enzymes, not the whole living cells that cause fermentation’s problems. The cost of enzyme production is often too high to use cell-free systems at scale, but we have developed a technology to lower the cost of enzyme production and stabilization. Our enzymes cost less and last longer, which enables us to save money and create products that can compete with their petroleum-based counterparts.

Value Propositon

• We use fundamentally different biology to reimagine all of sustainable chemical production, enabling a 60% reduction in predicted costs.

• Our cell-free system can create sustainable products that fermentation can’t.

• We take two disparate fields – enzyme engineering and enzyme immobilization – and combine them into a single high-throughput platform using synthetic biology.

patrick.sullivan@flux12.co mwww.flux12.com

Milestones:

Business Concept

Prototype/MVP Built

Company Incorporated

First External Users/Pilot

First Paying Client(s)

Funding Raised

Team:

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