Oculeze Detailer Leaflet 260225 FLIP

Page 1


Hydrates, lubricates and soothes irritated eyes

Comfort is everything

3-month shelf life after opening (10ml Bottle)

Resealable 0.6ml vials for up to four applications (dispose 24hrs after opening)

Lasts 2 times longer on the eye surface*

Your first choice

*Compared to non-lipid preparations

Hydrates, lubricates and soothes irritated eyes

Choose comfort… with up to three months shelf life after opening.

• Oculeze™ is available as a compact 10ml bottle and 10 x 0.6ml resealable vials.

• 10ml bottle includes a filter, maintaining sterility for up to 3 months after opening.

• Each resealable 0.6ml vial provides up to four applications. Dispose 24hrs after opening.

• Long shelf life.

Choose comfort… that lasts twice as long.

• Oculeze™ eye drops contain natural essential oils, which reduces evaporation1 compared to non-lipid ocular lubricants,2 which means that…

• Oculeze™ lasts twice as long on the eye surface*.

*Compared to non-lipid preparations

Your first choice… in ocular comfort…

• Contains natural active ingredients: glycerine (0.8%), aloe vera, chamomile and propolis extract; rich in topical polyphenols.

• Mechanical properties support improved ocular comfort.

• Phosphate free and pH neutral – NON STING!

• Suitable for animals including but not limited to dogs, horses, cats and rabbits.

• Part of the Millpledge portfolio of products.

Oculeze™ hydrates, lubricates and soothes irritated eyes.

• Suitable for any ocular condition where eye health is supported by providing additional moisture or lubrication.

• For animals with tired, dry or dull eyes.

• Drying of the eyes may occur due to ocular anatomy, abnormalities of the tear film, during travel or as a result of age-related tear film changes.

• Can be used alongside veterinary prescribed treatments with no contraindications.

Evaporation, %

Average of eye drops not containing lipids 0

Which pets benefit most?

• Brachycephalics or any animal with prominent eyes.

• For older animals where age-related changes may affect the tear film.

• To soothe dry eyes during travel.

A natural solution

• Glycerine as a lubricant, demulcent and humectant to soothe the ocular surface and support hydration.

• Aloe vera for natural soothing.

• Chamomile to reduce irritation.

• Propolis extract – rich in polyphenols.

Studies have shown that polyphenols support eye health3 by:

• Reduction in oxidative stress.

• Reduction in apoptosis.

• Modulation of the tear film.

Oculeze™
10ml applicator bottle.
10 x re-sealable 0.6ml Vials

The mechanical properties of Oculeze™ support improved ocular comfort

Low wetting angle.

Oculeze™ eye drops have a low eye surface contact angle1 which means they spread well across the eye surface.4,5,6

High surface tension to support tear film stability.

Oculeze™ eye drops have high surface tension1. This is due to the ability of polyphenols to form polymeric compounds on the tear film surface.

Together with a low eye surface contact angle, this helps support lubrication and tear film stability.

Reduced friction to soothe irritated eyes.

Oculeze™ eye drops contain glycerine as a key lubricating ingredient and have reduced friction2 compared to non-lipid containing ocular lubricants.7

Clinical study: Propolis, aloe vera and chamomile compounded natural eye drops8

A preliminary clinical study was carried out to investigate the effect of propolis, aloe vera and chamomile compounded eye drops. In six out of ten animals, the drops helped soothe the eyes, with signs of scratching and blinking resolving.

Administration

• Apply one to two drops to each eye.

• Safe to use as often as needed.

10ml applicator bottle

• When using for the first time, remove control ring from the cover cap.

• After removing the cap, turn the bottle upside down.

• With the dropper pointing down, press firmly until the solution starts to flow and apply to each eye.

• Replace the cap and use as needed for up to 3 months after opening.

0.6ml vials

• To open the vial, snap off the removeable lid

• Hold the vial upside down and press to deposit drops into each eye.

• Replace the lid to re-seal the vial.

• Each vial lasts up to 24 hours once opened.

Oculeze™

Surface tension, dynes/cm

Oculeze™

Systane™ Ultra High Performance Eye Drops

Refresh™ Optive Lubricant Eye Drops

Refresh™ Liquigel Lubricant Eye Gel

TheraTears™ Lubricant Eye Drops 0,00

Friction, F

Average of eye drops not containing lipids

Oculeze™

References

1. Testing of ophthalmic solutions lubricating properties 2022 09 Department of Polymer Chemistry and Technology, Kaunas University of Technology, 2022 10 Department of Tribology, Vytautas Magnus University

2. Tsubota K. and Yamada M. (1992) Tear evaporation from the ocular surface. Invest Ophthalmol Vis Sci.;33(10):2942-50

3. Favero, G. et al. (2021) Evidence of Polyphenols Efficacy against Dry Eye Disease. Antioxidants 10:190

4. Eftimov P. et al. (2015) Effect of hydrophilic polymers on the wettability, static and dynamic, of solid substrate covered by confluent monolayer of air-damaged SIRC cells. Biotechnol Equip. 4;29(2):390-394

5. Jang, Se et al. (2014). Comparison of Wettability for Ocular Prosthesis Depending on Different Kinds of Artificial Tear Eye Drops. Journal of the Korean Ophthalmological Society. 55. 1745

6. Bock U et al. (2018) Development of In Vitro Methodologies to Investigate Binding by Sodium Hyaluronate in Eye Drops to Corneal Surfaces. Open Ophthalmol J. 31;12:226-240 6

7. Černohlávek M. et al. (2021) Insight into the Lubrication and Adhesion Properties of Hyaluronan for Ocular Drug Delivery. Biomolecules 30;11(10):1431

8. Preliminary clinical study on the efficacy of propolis/ aloe vera/ chamomile compounded natural eye drops, Claudio Peruccio, Ophthalmology Referrals, Turin Veterinary Centre, Torino, Italy

Hydrates, lubricates and soothes irritated eyes

Choose your preferred presentation:

Code

YD01060 YD01100

Description

10ml applicator bottle. Includes filter to maintain sterility for three months after opening.

Freephone: 08000 11 22 88

Email: sales@millpledge.com Website: millpledge.com

10 x re-sealable 0.6ml Vials for use up to four applications (dispose 24hrs after opening).

Millpledge Veterinary, Whinleys Estate, Clarborough, Retford, Notts DN22 9NA Please recycle this leaflet

Oculeze™ Eye Drops 10 x 0.6ml Oculeze™ Eye Drops 10ml

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