CANNA MED BUSINESS JOURNAL

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EDITORIAL & ADVISORY BOARD

ANNE BOLDUC Group Publisher & President EDITOR IN CHIEF Guy J. Jonkman

ROBERT M. GOLDMAN, MD, PhD, DO, FAASP World Chairman-International Medical Commission Co-Founder & Chairman of the Board-A4M Founder & Chairman-International Sports Hall of Fame Co-Founder & Chairman-World Academy of Anti-Aging Medicine President Emeritus-National Academy of Sports Medicine (NASM) DR. RONALD KLATZ, MD, DO, is the physician founder and President of the American Academy of Anti-Aging Medicine. In 1984, Dr. Klatz was a pioneer in the clinical specialty of preventative medicine: as a principal founder of the National Academy of Sports Medicine and researcher into cannabis medicine elite human performance and physiology. Dr. Klatz is a best-selling author, and is columnist or Senior Medical Editor to several international medical journals. He is the inventor, developer, or administrator of 100-plus scientific patents, including those for technologies for brain resuscitation, trauma and emergency medicine, organ transplant and blood preservation. DR. ADAM ABODEELY MD, MBA, FACS, FASCRS is the founder/CEO of ReserveMD™ and is a Board Certified Surgeon specializing in gastrointestinal diseases and cancer. Realizing the benefits of cannabis for patients with such ailments, Dr. Abodeely expanded his medical cannabis practice to include patients with a variety of medical ailments. He is an active member in numerous international cannabinoid societies and he serves as Chairman of the Dispensary Review Committee for the Association of Cannabis Specialists. Dedicated to advancing the science and education of cannabinoid-based therapies, he has a special interest in formulating products which capture the unique benefits of cannabinoids.

DAVID B. MANDELL, JD, MBA, is a former attorney and author of ten books for clients, including For Doctors Only: A Guide to Working Less & Building More, as well a number of state books. He is a principal of the financial consulting firm OJM Group. He has co-authored the Category I CME Monograph Risk Management for the Practicing Physician which has gone through 5 editions since 1998 & is certified for 5-hour business of medicine CME.

SENIOR EDITOR Bernard Burt SEND EDITORIAL INFORMATION info@cannaMEDbusiness.com or P.O. Box 2699 Champlain NY 12919-2699 SUBSCRIPTIONS Yearly subscriptions prices in the United States are US $87 for 1 year, US $127 for 2 years, US $157 for 3 years. Canada are CDN $118 for 1 year, CDN $178 for 2 years, CDN $218 for 3 years. International US $199 for 1 year US $279 for 2 years, US $359 for 3 years. Send payment to: P.O. Box 2699, Champlain, NY, 12919-2699 6-12 WEEKS FOR FIRST ISSUE

CANNAMED BUSINESS REVIEW Chief Operating Officer, ANNE BOLDUC Systems Manager, DANIEL DOREY Director Human Resources, ESTHER AMAR Treasurer, STARR WYLKIE Group Publisher, ANNE BOLDUC Chief Editor, GUY J. JONKMAN PARTNERS American Academy of Anti-Aging Medicine American Med Spa Association

COPYRIGHTS Š 2019 BY CANNAMED BUSINESS REVIEW ALL RIGHTS RESERVED

e-mail: info@cannaMEDbusiness.com This issue is published by Publicom Inc., Montreal, QC. Postage

paid in Montreal, QC and Plattsburgh, NY. POSTMASTER:

SAHAR SWIDAN, Pharm. D., BCPS, ABAAHP currently serves as the Executive Director of Professional Development and Compliance at Slyngshot Health and CEO of Pharmacy Solutions. Dr. Swidan has over 25 years of experience in Personalized Medicine and Pharmacogenomics and serves as adjunct faculty at George Washington University, Wayne State University, and Chicago State University. Dr. Swidan is Board Certified and is an Advanced Fellow in Anti-Aging and Regenerative Medicine. She has authored several chapters, articles, and education materials in Pain Management and Personalized Medicine.

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Business Review of any industry standard, or as a

BRENT A. BAUER, M.D. as director of the Mayo Clinic Complementary and Integrative Medicine Program, Brent A. Bauer, M.D., has broad and varied research interests. Dr. Bauer's personal goal is to ensure that research conducted under the auspices of the Complementary and Integrative Medicine Program is always held to the same high standards as all other research at Mayo Clinic. He brought real, evidence-based knowledge to patients and physicians trying to incorporate the best of conventional and complementary medicine practices.

recommendation of any kind to be adopted by or binding upon

any spa owner. Reproduction of any portion of this issue by any

means (facsimile or electronically, for example) is strictly forbidden. The publisher assumes no responsibility for

return of unsolicited photographs or manuscripts. Subscriber:

Send subscription inquiries and address changes to: Circulation Department, CannaMED Business Review, P.O. Box

2699, Champlain NY 12919. Give old and new address, including postal code and the address label from most recent

issue. Allow six weeks for change. Printed in Canada. Legal

ALEX R. THIERSCH Founder and director of the American Med Spa Association (AmSpa), an organization created for the express purpose of providing comprehensive, relevant and timely legal and business resources for the medical wellness industry throughout the United States & Canada.

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CHERYL WHITMAN, is a published author, a popular speaker and a wellness-industry consultant with more than 30 years experience, including 15 years as the owner of a wellness spa in Fort Lee, New Jersey. As founder and CEO of Beautiful Forever, Cheryl spearheads a successful team of medical spa consultants and business professionals. In addition, Cheryl developed the Medical Spa Success System, a revolutionary program that provides a turnkey educational success system and consulting services package to help clients jumpstart brilliantly successful wellness medical spa businesses.

PUBLISHED SIMULTANEOUSLY in United States and Canada www.cannaMEDbusiness.com Phone: 727-522-5833








CANNA MED Business Review

HOW DO YOU GET CBD INTO YOUR EXISTING SPA?

By VERN MATHIS, COO of the NICE Corp, LLC

Adding CBD to Existing Spa Aesthetic Business

By now you have probably heard of CBD and you have probably heard or read about the health benefits associated with using CBD. You may have seen the success stories on the news, heard about people starting CBD stores. But how do you get CBD (Cannabidiol) into your existing business? You want to jump in and get your slice of the CBD pie and be part of this New Industry, but who do you trust? Where do you get CBD products? Should you white label and build your brand? How do you choose the right products for your business model? These are all great questions, and ones you will need to know going forward.

W

So let’s get started! hile

more

and

more our knowledge, and helping people and

businesses and entrepreneurs businesses navigate the CBD industry. decide to enter into the CBD When we started out over 15 years ago, we were

market, for some it can appear daunting. At our like most people today who were wondering family business, The Nice Corp in beautiful how to be successful and understand the Colorado, we are all about education, sharing Cannabis business. www.cannaMEDbusiness.com

Canna Spa

•

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WHO DO YOU TRUST IN THIS NEW CBD INDUSTRY? There is a misconception among some people that selling CBD hemp products is a tough process with lots of hard to understand rules and regulations. The reality is there are few laws regulating CBD. BEFORE ANY REGULATIONS WERE PUT INTO PLACE, MANY TOOK

ADVANTAGE OF THE

LACK OF REGULATIONS ON As we have grown, one of our goals is to make CBD PRODUCTS. THEY PRODUCED AND sure we remember why we entered the SOLD BOGUS PRODUCTS, SOME WITH business, and we are here for our clients. We ZERO

CBD

TO

UNSUSPECTING

make time for helping others who want to CUSTOMERS, LEAVING AN UGLY STAIN know how to enter the business.

ON THE INDUSTRY AND SIGNIFICANT DOUBTS IN CONSUMERS MINDS.

At the Nice Corp every employee has their But this is rapidly changing, and these get direct number on their business card, when rich quick flakes are dropping out as more our clients need an answer, they know they can and more people become educated about reach us quickly.

CBD: where it comes from, how it is extracted, testing transparency, and more.

Anyone interested in starting a CBD related business, or adding CBD products to an Additionally, the popularity of CBD hemp existing business, will quickly discover that products for medical purposes has been on the entering the CBD and hemp retail industry will rise for many years. Breaking into the industry involve a somewhat large learning curve that today with your own brand of CBD, can get may require guidance to navigate the ins and you going quickly, and enable you to rapidly outs of this rapidly expanding industry. CANNA MED

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CANNA MED Business Review

WHERE DO YOU GET CBD PRODUCTS?

Or you may choose to simply add CBD products We discussed her client base, average ticket from an already successful company to your sales, target market for new clients, and the existing business. The key to any successful types of products currently being sold in her business: meet the demand and adjust to the spa business. market swiftly. Starting a new CBD product business can be relatively inexpensive. Likewise, adding CBD products to an existing business has the opportunity to be a cost effective way to increase sales, customer base, and profits. Recently, while speaking at one of the many seminars we do around the country, I was asked by the owner of a Health and Beauty Spa if there was a way to incorporate CBD products into her existing business. www.cannaMEDbusiness.com

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WHEN YOU’LL JUMP IN & GET YOUR SLICE OF THE CBD PIE? expected to grow right along with it. That’s great news! Health and wellness spas are an excellent place to stimulate the five senses: sight, sound, touch, smell, and taste. These are used in various manners to create a pleasant and, likely, memorable experience for your clients. But how can you use CBD to stimulate these five senses? Thinking of CBD products in the terms of an Add-On product (or up-sell), let’s It was also important to know what the average

take a look:

spa experience was like for both repeat and new clients. We now had a clear picture of her

Sight: Undoubtedly you are already aware

business model.

and using the power of sight through lighting, colors, art, employee appearance,

LET’S LOOK AT THIS AS A CASE STUDY

etc. Thinking in terms of “Add-On”, how

FOR INCORPORATING CBD PRODUCTS

could you display these products in a

INTO AN EXISTING BUSINESS.

pleasing and eye catching manner?

The health and wellness spa industry performance is directly related to the ebb and

Now that you have directed the client’s

flow of consumer disposable income and

attention towards the CBD products, consider

confidence in the stability of the economy.

sound. Again, you likely have already

Since 2017, demand for industry services has

determined the appropriate type of music, or

increased during current favorable economic

other sources of sound, such as trickling

conditions. Consequently, as per capita

water, or rolling waves, but how can you apply

disposable

it towards the CBD products?

income

among

consumers

continues to increase, industry revenue is CANNA MED

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SHOULD YOU WHITE LABEL & BUILD YOUR CBD BRAND? One way is to train yourself and staff to explain the healing benefits of CBD, how it will improve their experience at the spa and continue on after leaving the spa in tone and volume that is in cohesion with the atmosphere you are trying to create. Continuing on, the sense of touch can be utilized, first, by offering samples for the client to apply to their skin before adding it to their services. Once chosen, the product

Offer a variety of salty, sweet, and sour etc to

can be used to enhance the therapeutic

cover all client taste preferences.

benefits of human touch during their service.

You can use these five senses to encourage the clients to purchase CBD products to use at

I know you already realize scent has a direct

home. When used at home, the product will

effect on memory and emotion. Using

simulate the memory of their pleasant

terpenes in a diffuser is an excellent way to

experience at your spa and likely move them to

use the sense of smell, increasing a positive

return. You are increasing direct sales through

experience, and memory, for the client. There

Add-ons, TWICE: for use in the spa and as a

are a wide variety of scents currently

take-home product. The potential for

available.

increasing return client visits is raised substantially through these methods.

And finally, taste. Offering a one dose tincture before a massage or a gummy to suck on can

Hopefully your business is a process-driven

increase the overall satisfaction and

business, and not a market-driven business.

experience for the client while at the spa.

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WILL YOU CHOOSE THE RIGHT CBD PRODUCTS FOR YOUR SPA? A FEW IDEAS: CBD Massage Oil CBD Tincture in a variety of flavors CBD Face Creams CBD Cosmetics Eyeshadow, Foundation, Mascara, Lipstick CBD Pain Relief Salves CBD Gummys in a variety of flavors and formulas blended for specific concerns or a particular part of the body.(CBD-CBNA process driven Spa will have a solid process for every aspect of the client relationship, from the first meet and greet, to how you exit a client, and the follow up with that client after the visit. Process-driven businesses are not affected by market ups and downs. Business remains steady with no large upticks and downticks in client flow and sales. When you have a solid process, you have more quality time to spend building relationships with your clients, and that will directly, and positively impact your bottom line. What kind of CBD products are appropriate and available for use at Health and Wellness

CBG-CBC ) CBD Coffee and Tea Organic All Natural Terpenes Organic Hemp Extract Shampoo and Conditioner The health and wellness spa industry performance is directly related to the ebb and flow of consumer disposable income and confidence in the stability of the economy. Since 2017, demand for industry services has increased during current favorable economic conditions. Consequently, as per capita disposable income among consumers continues to increase, industry revenue is expected to grow right along with it.

Spa? CANNA MED

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HOW DO YOU FIND A CBD COMPANY YOU MAY DEVELOP A GOOD RAPPORT WITH?

That’s great news! This coincides beautifully with the growing desire for consumers to take a more holistic approach to their well being. In light of all this great news, one can easily see the potential for growth opportunities and new products is massive! My best, and strongest advice to anyone considering adding CBD products to their health and wellness spa: Do it now! Find a company you can develop a good rapport with, who understands and addresses your needs, and has a true desire to see you succeed. Start up costs for White Label products can be pricey depending on how many you start with, but if your adding to your existing business it’s well worth the investment. Whichever way you choose to go, the costs and risks are minimal, and the timing is prime!

www.cannaMEDbusiness.com

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IS THE TIMING PRIME FOR YOUR CBD MEDICAL SPA?

Vern Mathis has over a decade of experience as a professional grower, cultivator, innovator in the propagation and marijuana genetics and as a dispensary owner. He has been an active participant and industry leader from the early days of medical marijuana to the current growth of recreational marijuana and the booming CBD industry. Vern has started and operated Vern Mathis is the Chief Operating Officer of the NICE CBD company, a family owned and operated business in which his daughter Copyright 2019 Vern Mathis

Karina, a seasoned CBD developer and business

three licensed dispensaries in two states and a operated a licensed grow facility. He is a former president of the Oregon Cannabis Growers Association. n

leader serves as the CEO. CANNA MED

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www.cannaMEDbusiness.com




CANNA MED Business Review

BIG PHARMA PICKS UP ON MEDICAL MARIJUANA

TILRAY & SANDOZ WILL SELL MEDICAL MARIJUANA IN 41 COUNTRIES

A

NOVARTIS SUBSIDIARY IS PARTNERING WITH A CANNABIS COMPANY TO SELL MEDICAL MARIJUANA WORLDWIDE.

By Ashley P. Taylor

“If a product comes into a pharmacy with the Sandoz logo co-branded on it, or if a pharmaceutical sales rep is talking to a physician about a product that’s branded as Tilray and Sandoz, it lends credibility to that product.”

The Canadian marijuana company Tilray announced that it has signed an agreement to partner with Novartis subsidiary Sandoz to sell medical marijuana in countries where it is legal, currently numbering 41. This is likely the first time a major pharmaceutical company has gotten into the medical marijuana business, STAT notes.

Under the agreement, the two companies may market Tilray’s nonsmokable, noncombustible medical marijuana products worldwide, develop new medical marijuana products together, and educate pharmacists and physicians about those products, according to the statement.

“It just made sense for us to reach an agreement with a company like Sandoz, which is known for its focus on patients, its reliable supply chain, a well-established sales force and a global distribution network,” Tilray CEO Brendan Kennedy tells Bloomberg.

Tilray has been working with Sandoz Canada since March and have co-branded eight ingestible oil and capsule medical cannabis products, Bloomberg reports. The new global agreement is an outgrowth of that collaboration.

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TILRAY & SANDOZ WILL MARKET NON-SMOKABLE, NON-COMBUSTIBLE MED CANNA PRODUCTS WORLDWIDE The agreement is exclusive in that Sandoz has promised not to partner with another pot company and Tilray has agreed not to partner with another pharmaceutical company on noncombustible products, according to MarketWatch.

The two companies will work together to commercialize Tilray’s non-smokable medical marijuana offerings, co-brand certain products, develop new products and educate pharmacists and physicians about pot.

Kennedy tells MarketWatch that it isn’t planning to shift focus away from recreational marijuana, which it currently sells in Canada, where recreational weed has been legal since October. “For Tilray, both are equally important,” he says.

“It just made sense for us to reach an agreement with a company like Sandoz, which is known for its focus on patients, its reliable supply chain, a well-established sales force and a global distribution network,” Tilray Chief Executive Officer Brendan Kennedy said in a phone interview. “If a product comes into a pharmacy with the Sandoz logo co-branded on it, or if a pharmaceutical sales rep is talking to a physician about a product that’s branded as Tilray and Sandoz, it lends credibility to that product.”

TILRAY GOES GLOBAL WITH NOVARTIS MARIJUANA SALES PARTNERSHIP By Kristine Owram Firms will work together to develop and distribute cannabis ‘It lends credibility to the product,’ Tilray CEO says Tilray Inc. has signed a global partnership with a division of Swiss drug giant Novartis AG to develop and distribute its medical marijuana in legal jurisdictions around the world.

The partnership will also allow Tilray to “capture early share in new medical cannabis markets as they come online,” Cowen analyst Vivien Azer wrote in a note, adding that it should boost the pot company’s top and bottom lines. “While we would continue to expect Tilray to have some of its own feet on the ground, the Sandoz expansion allows Tilray to invest more modestly and leverage Sandoz’s scale.”

The Canadian pot firm said Tuesday it’s reached an Nanaimo, British Columbia-based Tilray and Sandoz agreement with Sandoz AG to boost the availability of Canada have been working together since March, medical cannabis products globally, building on an when they announced an alliance to develop new existing alliance with Sandoz Canada Inc. medical cannabis products and collaborate on research and education. The companies also cobranded eight oil and capsule medical cannabis products and are joint members of the Common Initiative, a group that’s urging Canada to allow distribution of medical pot in pharmacies. Currently it’s only available via mail. The partnership with Sandoz Canada “has been successful,” Kennedy said. “It’s been a very good experience, their team and their culture matches well with ours, we share similar values and visions for the future of the medical cannabis industry globally.”

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NOVARTIS-TILRAY PACT ADDS LEGITIMACY TO A MARIJUANA INDUSTRY THAT WAS DOMINATED BY DRUG CARTELS

Canna Partners

For a time, Tilray was the largest cannabis company by market value until it was eclipsed by Canopy Growth Corp. The shares have risen almost fourfold since its July IPO but lost 78 percent from their peak on Sept. 19 reducing the market value to $6.1 billion. It has products available in 12 countries and operations in Canada, Australia, New Zealand, Germany, Portugal and Latin America.

TILRAY PARTNERS WITH NOVARTIS IN BIG PHARMA’S FIRST DEAL OF ITS KIND WITH BIG MARIJUANA By Max A. Cherney Tilray CEO says distribution deal is first global partnership, ‘will allow us to expand into more markets, more quickly’. Tilray Inc. announced that it has inked a global supply and distribution agreement for medical marijuana with pharmaceutical giant Novartis AG, continuing a trend of legacy industries linking up with the new breed of marjiuana producers.

Brendan Kennedy Photographer: Galit Rodan/Bloomberg “Around the world, people are substituting medical cannabis for traditional pharmaceutical products,” Kennedy said in a telephone interview Monday evening. “Medical cannabis is disrupting Big Pharma, and Sandoz and Novartis are smart for being ahead.” A guide to pot stocks: What you need to know to invest in cannabis companies

Kennedy said that the pact is the first major partnership of its type between a cannabis company and a big pharmaceutical business. The deal has its Following investments by big beverage and tobacco origins in Canada, the second country in the world companies in Canadian pot producers focused on the and only member of the G-7 to legalize marijuana recreational market, the Novartis-Tilray pact adds for recreational use. Through the Novartis further legitimacy to an industry that until recently was subsidiary Sandoz, Tilray signed a similar agreement dominated by drug cartels, outlaw motorcycle clubs and to distribute and sell medical cannabis products in smugglers. For Tilray, the deal is the culmination of 2017 — an agreement that prompted this much larger months of work for Chief Executive Brendan Kennedy, deal, which expands the agreement to the roughly 41 who said in an interview that the partnership will give countries around the world that have medical his company a sales and distribution channel in dozens cannabis laws, a number that Kennedy says will likely of countries. increase in the future.

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Canna Partners

ETF MJ IS THE GO-TO DESTINATION FOR CANNA STOCKS

Tilray grows marijuana for the medical and recreational markets. As a part of the agreement, Tilray will be able to use Sandoz’s muscular global sales channels to help smooth the way for the marijuana producer to introduce medical products where it is legally allowed to do so, Kennedy said. Tilray said that it cut an exclusive deal with Novartis, which is not allowed to partner with another pot company, and Tilray cannot make a pact with another pharmaceutical business on non-combustible products. “The key point is that it will allow us to expand into more markets, more quickly,” Kennedy said. “This is an agreement that will take advantage of Sandoz’s global footprint and leverage their brand, which inspires trust and confidence with pharmacists around the world. Also, we can use their salesforce to educate physicians and pharmacists around the world — which can be a challenge.” Kennedy also said that the companies will work together to develop new products, and have several that focus on defined dosage. The agreement announced Tuesday covers non-smokable and non-combustible medical products.

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DON’T MISS: HOW ONE EXCHANGE BECAME THE GO-TO DESTINATION FOR CANNABIS STOCKS Earlier this year, Constellation Brands Inc. STZ invested $4 billion in the Canadian pot producer Canopy Growth Corp. CGC WEED. And in December, Altria Group Inc. MO announced a $1.8 billion investment in Cronos Group Inc. CRON, CRON. Kennedy said Novartis was in talks with “a number” of Canadian-licensed marijuana producers but ultimately settled on a deal with Tilray. Kennedy said that the deal with Novartis doesn’t signal that Tilray is going to prioritize the medical cannabis market ahead of recreational pot, which it currently sells in Canada. “For Tilray, both are equally important,” he said. Tilray stock has gained nearly 200% since it began trading earlier this year after its initial public offering. The ETFMG Alternative Harvest ETF MJ which tracks cannabis stocks is the go-to destination for canna stocks. n.

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CBD WELLNESS: SEPARATING FACT FROM FICTION

HEMP IS A MULTI-PURPOSE & ECO-FRIENDLY PLANT

CBD WELLNESS IS A HOT TOPIC THESE DAYS. THERE ARE VERY FEW TOPICS IN

AND CAUSE SO MUCH CONFUSION AS

Hemp is highly nutritious and is a potent pain reliever, antioxidant and anti-inflammatory. This oil has come under a lot of legal and moral questions for decades. Opinions may differ but what can’t be ignored is the incredible wellness power CBD oil seems to possess and how versatile it is as a supplement and natural remedy.

THE CANNABIS PLANT. AS IT GROWS IN

What Is It?

THE WELLNESS SPACE THAT CURRENTLY GENERATES AS MUCH CONTROVERSY

POPULARITY AND AS MORE COUNTRIES ACCEPT AND ADOPT CANNABIS, IT’S MORE IMPORTANT NOW THAN EVER TO KNOW PRECISELY WHAT IT IS AND WHAT IT’S NOT.

C

Cannabis can be broken down into 2 subspecies, marijuana and hemp. We are primarily concerned with hemp for the sake of this article, and these days people recognize that it is a multipurpose and eco-friendly plant, that’s been utilized for millennia for both a fiber and health. Cannabidiol oil (Hemp CBD oil) is gaining in popularity because it has so many uses.

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Like we mentioned above, Cannabis has different species: marijuana is one of them and hemp is another. This is often where people get confused. Even though marijuana and hemp are species of the same plant (cannabis), chemically, they are so very different. All cannabis contains an array of healthy plant compounds called cannabinoids. These are to the cannabis plant what flavonoids are to vegetables and fruits, in that they are powerful compounds with various wellness properties. There are approximately a hundred cannabinoids that can be found in cannabis. The 2 most known ones are THC (tetrahydrocannabinol) and CBD (cannabidiol). THC is the cannabinoid that is responsible for creating a high but it’s very important to note where it is found and in what amounts. •

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HEMP IS NUTRITIOUS, HAS POTENT PAIN RELIEVER, IS ANTI-OXYDANT & ANTI-INFLAMMATORY As things started to change for hemp in early 2000’s, we started to see more of a resurgence for CBD oil as well, especially around the 2017 time-frame. Since CBD has been villainized in modern society for so long, there’s now very limited understanding behind the products and we are going through a new period of education in regards to hemp wellness.

BENEFITS OF CANNABINOIDS CBD is found in much higher numbers in hemp with minuscule amounts THC, while marijuana is generally very low in CBD and high in THC. It’s important to note that CBD doesn’t get you high at all. In the U.S. laws, the difference between hemp and marijuana has everything to do with THC percentages. To be labelled as hemp, it can’t have more than 0.3% THC. Marijuana can have THC content over 20%. Cannabinoids play a larger part in our general health than people realize as they don’t just come externally from cannabis, they are also produced in our bodies. These internal versions are called endocannabinoids and we actually have a network in our body called the endocannabinoid system (aka ECS). The main purpose of the ES is to keep your body in balance (homeostasis). It’s a much bigger deal than most people give it credit for as it plays a major role on pain, inflammation, sleep, appetite, stress levels, exercise, reproduction, metabolism, and a whole lot more.

HISTORY OF THE INDUSTRY CBD was 1st brought into western medicine in the 1800’s and was researched significantly during that time period. Confused political leaders and industry led propaganda, primarily from pulp and paper, eventually caused cannabis prohibition in the early to mid 1900’s. This also included all industrial hemp and CBD oil applications. Unfortunately, this prohibition caused much of the hemp oil research to be forgotten for the remainder of the 20th century. CANNA MED

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Researchers have known there was health and wellness possibilities with plant cannabinoids, but the demonization of the plant stopped any research from being performed in the US. But things are changing in a big way and more and more research is being done. The medical use and benefits of marijuana has put a spotlight on the topic of using cannabis products for wellness and health, but the we need to take note of the difference between marijuana and hemp oil. The main difference is in the plant being used to make the product. Cannabidiol oil isn’t usually made from marijuana, rather it’s most mostly made from hemp. The part of the plant matters as well as Hemp CBD oil is also very different from hemp seed oil, because it’s extracted the leaves, stalks and flowers of hemp, not the seeds. The research is showings that CBD products are beneficial for reducing a number of ailments. Upcoming research has been showing that each of these conditions is likely related to dysregulation of the endocannabinoid system. Although it’s not as well known as the immune or cardiovascular system, it is a vital part of the body and it was found by looking into what effects cannabis has on the body. The endocannabinoid system is comprised of endocannabinoids and their receptors. These are located all over the body from the brain to immune cells and glands. This unique system works differently on different parts of your body but the result is homeostasis which is a balanced state. www.cannaMEDbusiness.com


CANNA MED Business Review

HEMP POSSESSES WELLNESS POWER & HOW VERSATILE IT IS AS A SUPPLEMENT & NATURAL REMEDY

Research mentioned in the Scientific American found endocannabinoids to be mostly responsible for the “runners high” athletes feel. For those people not familiar with it, a runners high is a natural feeling of euphoria that increases your sense of well-being and decreases your perception of pain.

What It Can Do:

3. Helps To Fight Multi-Drug Resistant Bacteria Research has shown that cannabinoids have a rare ability to destroy bacteria, more importantly the drugresistant strains. Researchers have concluded that hemp derived CBD likely does this by inhibiting T-cell proliferation, rather than having antibacterial properties.

HERE ARE A FEW OF THE USES FOR THIS INCREDIBLE OIL:

1. Pain Relief People dealing with pain may find relief with CBD. Better still is that CBD doesn’t cause dependence making it an amazing option for people wanting to stay away from opioids.

2. Seizure Prevention CBD has anti-seizure properties. In a study put out by the New England Journal of Medicine, CBD lowered the frequency of seizures by 23% more than the placebo group. Even the FDA appears to agree that cannabis-derived products may be helpful. In April 2018 FDA advisers put forth a product that is cannabis based and promises to help with seizures.

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However it is able to destroy bacteria, it seems to be an excellent weapon against the antibiotic resistant “superbugs” that are rapidly becoming a serious threat to our health.

4. Helps To Reduce Inflammation Having some inflammation is healthy as that is the body’s way of fighting off infection. But, when inflammation is ongoing, it can lead to all kinds of significant problems. In our current society, lifestyle and diet play a big part in inflammation. But, when people are already exercising, getting good sleep, and eating a clean, healthy, nutrient-dense diet, then hemp oil can help. Research has shown it to have antiinflammatory properties, so by adding hemp drops to your supplement routine and/or using it externally by way of a CBD hemp cream, you can reduce and minimize inflammation-based discomfort.

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CANNA MED Business Review

CBD Wellness

MARIJUANA & HEMP ARE SPECIES OF THE SAME CANNABIS PLANT BUT CHEMICALLY THEY ARE DIFFERENT 7. Improved Heart Health Keeping a healthy diet and lifestyle is priority for good heart health, but CBD oil can also help out. Research indicates that cannabidiol can help to reduce: blood pressure, stress induced cardiovascular responses, and artery blockages. As mentioned above, it’s great at helping with preventing oxidative stress as well as inflammation. Interestingly enough, both of these things are usually precursors to heart related issues.

8. Improves Skin

5. Reduces Oxidative Stress Oxidative stress is when our body has way too many free radicals and can’t neutralize them all with antioxidants. It’s responsible for many of today’s ailments and is now more of a problem than it has been previously because our environment is far more toxic than it was. A research study from 2010 has shown that hemp oil behaves as an antioxidant while a different study suggests CBD has neuro-protective qualities helping to reduce any neurological damage caused by free radicals.

6. Promotes Healthy Weight Cannabidiol can help with increasing mitochondria that help burn calories, stimulates proteins and genes that help to break down fat, and helps maintain healthy blood sugar levels. CBD also helps your body to create brown fat from white fat. White fat is what we generally think of when we think about unhealthy body fat. Brown fat is in small deposits and it behaves quite differently than white fat. Brown fat is said to better your health by helping your body to burn white fat, generate heat, and regulate blood sugar levels. As you can see, it’s great for keeping a healthy weight.

CANNA MED

BUSINESS Review •

As well as all the things we’ve mentioned that it can help with on the inside, it can also can be used topically to help with skin conditions. Research indicates that show cannabidiol oil is very useful for treating skin conditions by helping to regulate the skin’s oil (sebum) production. Additionally it contains many nutrients such as vitamin E that can help with improving and protecting your skin. It’s also full of amino acids, vitamins, and fatty acids. Essential fatty acids, like omega-6 and omega-3, are good for your general health but they are also fantastic for your skin by helping to give your skin a gentle, supple appearance. The amino acids help your skin with generating elastin and collagen, which allows your skin to stay moisturized thus preventing wrinkles. With all that it helps with, it’s no wonder that it has found a home in the skin care product sector. n

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INTRODUCING A NEW, NON-OPIOID PAIN SOLUTION:

RAPIDCBDTM By Larry Banegas, Kumeyaay.com

The report “World Analgesics Market - Opportunities and Forecasts, 2015-2022” projects that the world analgesics market would reach $26.4 billion by 20221. Pain sufferers have long regarded plant botanicals as a source of healing; there are more than 100 plants known to have pain relieving properties2. Consumers have sought retail brands of topical pain relief with menthol as an active ingredient3. There is a “new” botanical that consumers need to be aware of for pain relief: cannabidiol. In a study published by the National Institutes of Health4, it is stated that, “The nonpsychoactive cannabinoid, cannabidiol (CBD), has great potential for the treatment of chronic and 'breakthrough’ pain.” The study also states, “Chronic pain relief can be best achieved through the transdermal route.” Today, the United States faces a health epidemic: prescription opioid addiction. To address this problem, manufacturers are producing a new topical combination of CBD with menthol. These non-habit forming ingredients are a welcome solution for consumers who do not wish to pursue prescription opioid pain medications or are looking for an alternative to prescription pain medicine. The irony is that CBD is anything but “new”. CBD is a naturally occurring component of the hemp plant. Hemp is from the cannabis genus and cannabis for medicinal use dates back to the ancient Chinese emperor, Shen-Nung (c.2700 B.C.). Having compiled the medical encyclopedia called, Pen Ts'ao,5 Shen-Nung is regarded as the Father of Chinese Medicine. Cannabis or “Ma”was used by the Chinese to treat weaknesses (menstruation), gout, rheumatism, malaria, beri-beri, constipation, and absentmindedness. During the second century A.D., the Chinese surgeon, Hua T'o, began to use cannabis as an anesthesia. CBD is activated in the body through CB2 receptors located in the skin. CB2 receptors play a role in antinociception, or the relief of pain.6 Menthol is a known active ingredient with cooling properties. Working similar to ice, menthol binds with temperature-sensitive receptors in the skin and is thought to modulate pain signals within the body’s natural pain relieving systems. CBD, known to be hydrophobic and lipophilic, does not dissolve or emulsify readily in water, but will dissolve in fat. Bioavailability of CBD depends on the way that the cannabinoid is delivered into the human body. Today, science has enabled CBD to be water soluble as well as time-release. The new topical pain cream, RapidCBD™, delivers a powerful combination of micro-encapsulated time-released CBD called Cebidiol™. In Cebidiol™, consumers will benefit from menthol plus eight additional homeopathic ingredients including lavender and rosemary essential oils to relieve pain. The RapidCBD™ Cooling Pain Cream is ideal after strenuous activity and has been proven to be as effective and work as fast as an FDA approved OTC topical pain relief solution. The immediate availability of RapidCBD™ is welcome news for consumers who are seeking a non-opioid solution for muscle aches, strains and joint pain. 1 -http://www.prnewswire.com/news-releases/analgesics-market-is-expected-to-reach-264-billion-globally-by-2022-575688921.html 2 -http://www.motherearthliving.com/health-and-wellness/the-best-herbs-for-pain-relief.aspx 3 -http://health.usnews.com/health-products/top-rec-topical-analgesics-arthritis-joint-pain-135 4 -http://www.ncbi.nlm.nih.gov/pubmed/20545522 5 -https://www.psychologytoday.com/blog/the-teenage-mind/201105/history-cannabis-in-ancient-china 6 -https://en.wikipedia.org/wiki/Cannabinoid_receptor

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Micro-encapsulated, time released. Temporarily resolves muscle and joint pain associated with back pain, neck pain, arthritis, muscle strain, bruises and sprains.

DESCRIPTION Enjoy an instant and continual cooling, soothing and pain relief experience with RapidCBD™ Cooling Pain Cream. We combine micro-encapsulated, time-released Cebidiol™ with stimulating menthol and 8 homeopathic ingredients, along with lavender and rosemary essential oil to relieve aches and pains. This gel cream is ideal for use after strenuous activity and has been proven to be effective and work fast as a topical pain relief solution.

Doctor Approved "RapidCBD has really helped my patients to overcome discomfort and greatly improved their quality of life."

Goodbye Pain

Hello Relief. For more info call: 1(855)-979-6751

Isodiol S.A. Rue du Mole 1 c / o Athemis Gestion SA 2000 Neuchatel / Switzerland www.isodiol.com • 1(855) 979-6751


Printed in Canada


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