To understand why opioids are so dangerous, you first have to understand how your brain processes pain. Let’s say you bang your knee on the doorjamb. Pain receptors in your skin register that something happened to your knee. Those receptors send signals to your brain and spinal cord. There, your brain processes those signals as pain, and your body produces natural opioids to stop them. These chemicals slow your breathing, create a feeling of well-being and block pain signals so you can return to a pain-free state.