Liver Specialist in Kerala

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Hepatoblastoma in Children: Symptoms & Causes

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Hepatoblastoma is a rare form of liver cancer that primarily affects children. It originates in the liver cells and can cause a range of symptoms. Recognizing the early signs of hepatoblastoma is crucial for early detection and treatment In this article, we will explore the symptoms and causes of hepatoblastoma in children, providing valuable information for parents and caregivers.

Symptoms of Hepatoblastoma:

Abdominal Swelling:

One of the most common symptoms of hepatoblastoma is the presence of a firm mass or swelling in the abdomen. It may cause the child's abdomen to appear larger or distended.

Unexplained Weight Loss: Children with hepatoblastoma may experience significant weight loss, often accompanied by a decrease in appetite. If your child is losing weight without any apparent reason, it's important to consult a healthcare professional.

Abdominal Pain: Children with hepatoblastoma may experience persistent or intermittent pain in the abdominal region. The pain may be dull or sharp and can be accompanied by discomfort.

Nausea and Vomiting:

Hepatoblastoma can cause nausea and vomiting in affected children. If your child is experiencing these symptoms without any apparent cause, it's essential to consult a healthcare provider.

Jaundice:

Jaundice, characterized by yellowing of the skin and eyes, can be an indication of hepatoblastoma. It occurs when the liver is unable to properly process bilirubin, a yellow pigment produced during the breakdown of red blood cells.

Causes of Hepatoblastoma:

The exact cause of hepatoblastoma remains unknown. However, several risk factors have been identified, including:

Genetic Syndromes:

Children with certain genetic syndromes, such as Beckwith-Wiedemann syndrome, familial adenomatous polyposis (FAP), and trisomy 18, have an increased risk of developing hepatoblastoma

Premature Birth:

Studies have suggested a link between premature birth and an increased risk of hepatoblastoma in children. Premature infants may have a higher susceptibility to developing certain types of cancers, including hepatoblastoma.

Inherited Conditions:

In rare cases, hepatoblastoma may be inherited from a parent who carries a specific gene mutation However, most cases of hepatoblastoma are not inherited.

Exposure to Certain Substances:

While rare, exposure to certain substances during pregnancy, such as certain medications or chemicals, has been associated with an increased risk of hepatoblastoma. However, more research is needed to establish a direct causal relationship.

Conclusion:

Hepatoblastoma is a rare but serious form of liver cancer that primarily affects children Recognizing the symptoms and risk factors can aid in early detection and prompt treatment. If your child is experiencing unexplained weight loss, abdominal swelling, pain, jaundice, or other concerning symptoms, it is important to consult a healthcare professional for further evaluation. Early diagnosis and treatment can significantly improve the prognosis for children with hepatoblastoma, highlighting the importance of raising awareness about this condition.

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