Background: A chronic illness presenting in adolescence may lead to emotional and behavioral problems, as well as low school performance. However, there are reports on psychological health and school performance in adolescents suffering from chronic illness since early childhood that do not differentiate between the latter and healthy peers. Aim of the present study was to determine possible differences between healthy and chronically ill adolescents regarding self-perception, emotional and behavioral problems and school performance.
Methods: The study participants were 46 adolescent patients, 23 suffering from hemophilia and 23 from asthma. The control group consisted of 29 healthy adolescents. Study evaluation included information given by adolescents, one of the parents and one school teacher. The study used questionnaires exploring psychological problems, self-perception and self-esteem, as well as school performance.
Results: Deviant hyperactivity ratio was higher in adolescents with chronic illness related to normal hyperactivity ratio. School performance was also lower in the study group compared to controls, without correlating to days of school absence. No statistically significant difference was found between the two groups regarding the rest of psychological problems studied or regarding self-perception.
Ioannidou Maria
Adramerina Alkistis
Teli Aikaterini
Economou Marina
1st Pediatric Department, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki
Hatziagorou Elpis
3rd Pediatrician Department, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki
Pergantou Helen
Bleeding Disorders' Unit, "Agia Sophia" Hospital, Athens
Conclusions: The study revealed differences between chronically ill adolescents and healthy peers in terms of manifestation of divergent behaviors connected to school life, but did not confirm the presence of emotional problems. The study findings indicate the presence of adaptive mechanisms in adolescents in managing their chronic illness.
Key words: adolescence, school performance, hyperactivity, chronic illness
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37.
Correspondence
Topalidou Aikaterini
Propontidos 14, 66132, Drama T. +302521098979, 6974396678
E. topalidouaik@yahoo.com
Tic Disorder and Comorbidity in Infancy and Early Childhood. An epidemiological study in children aged 4-8 years
Topalidou V. Aikaterini
Ministry of Education and Religious AffairsDepartment of Primary Education of the Prefecture of Kavala, Eastern Macedonia, Greece.
Topalidou V. Aikaterini
Msc Clinical Mental Health, Aristotle University of Thessaloniki, Greece.
Tsapaki Eva-Maria “Agios Charalambos” Mental Health Clinic, Herakleion Crete, Greece.
Tsapaki Eva-Maria
1st Psychiatric Department - School of Medicine –Faculty of Health Sciences , Aristotle University of Thessaloniki, General Hospital “Papageorgiou” Thessaloniki, Greece.
Fountoulakis N. Konstantinos
3rd Psychiatric Department - School of Medicine - Faculty of Health Sciences, University Hospital “AHEPA”, Aristotle University of Thessaloniki, Greece.
Vargiami Efthimia
Zafeiriou I. Dimitrios 1st Pediatric Department, General Hospital “Ippokratio”, School of Medicine - Faculty of Health Sciences, Aristotle University of Thessaloniki, Greece
Topalidou V. Aikaterini, Tsapaki Eva-Maria, Fountoulakis N. Konstantinos, Vargiami Efthimia, Zafeiriou I. Dimitrios
Abstract
Introduction: The purpose of this study was to investigate the occurrence of Tic Disorder in children aged 4-8 years in the general population and the comorbidity with other Neurodevelopmental Disorders. An additional goal was to identify the likelihood of correlating Tic disorder with characteristic intense behaviors of Neurodevelopmental Disorders, as well as the likelihood of associating the Tic occurrence with traumatic events, phobic or stressful situations experienced by the child.
Method-Sample: The data collection, correlations, and analysis related to Tic Disorder, performed for 149 students of Primary Education in the area of Prefecture of Drama at Eastern Macedonia and Thrace, Greece. The data collection carried out with a questionnaire to the parents of the children.
Results: The data collected from parents showed that of the 149 children who participated in 18.8% of boys and 12.7% of girls showed "Simple Tic". Multiple/complex Tics showed 23.5% of boys and 10.1% of girls. Tics are more related to age (p = 0.035), school attendance (p = 0.045) and consequently the difficulty that children face as a whole. It was also noted the predominance of "Multiple Tics in both categories of Tic" (motor and vocal), even in children who do not have a diagnosis ( p= 0.025). The time analysis showed that last year, during the covid-19 pandemic period, 12.8% of children aged 4-8 years had motor tics and 12% had vocal tics (p ≤ 0.01). Statistical analysis showed that some behaviors characterized by impulsivity/ hyperactivity strongly correlated with the existence of Tics (p ≤0.05). The analysis for the traumatic events in the child's life or the situations that cause anxiety or fear in the child showed that there is a strong correlation with the appearance of tic (p ≤ 0.001). In the descending order, the highest percentage observed in the situations related to school 11.5%, followed by situations that cause fear 9%, the peers’ company 6.4%, a combination of factors 6.4%, and traumatic event 3.8%.
Discussion: It is noted that many children experience difficulties associated with Tic Disorder, whether they are diagnosed or not, and yet exhibit behaviors that affect their daily lives, their relationships with significant others, and generally their functionality in the social context and their quality of life.
Keywords: Tic Disorder, GTS, childhood, early life trauma, stress
ASD:
OCD:
ODD:
CD:
DSM: Diagnostic and Statistical Manual of Mental Disorders
ICD: International Classification of Diseases
YGTSS: Yale Global Tic Severity Scale
TD: ΔΤ-Διαταραχή Τικ
CTD: Χρόνια Διαταραχή Τικ
TS ή GTS: Σύνδρομο
Tourette ή Gilles de la Tourette
Kruskal –Wallis Test.
Cronbach’s Alpha, 8200.
Kurlan et al. (2001)
Βιβλιογραφία
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2. Specht, M.W., Woods, D.W. και Piacentini, J. Clinical Characteristics of Children and Adolescents with a Primary Tic Disorder. Journal of Developmental and Physical Disabilities. 2011, σσ. 15-31.
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5. Martino, Davide και Leckman, James. Tourette Syndrome. New York : Oxford University Press, 2013.
6. Ganos, C., Martino, D. και Pringsheim, T. Tics in the Pediatric Population: Pragmatic Management. Movement Disorders Clinical Practice. 2017, σσ. 160-172.
7. Ganos, Christos, Munchau, Alexander και Kailash, Bhatia. The Semiology of Tics, Tourette's, and Their Associations. Mov Disord Clin Pract. 2014, σσ. 145-153.
8. Martino, Davide, Ganos, Christos και Pringsheim , Tamara. Tourette Syndrome and Chronic Tic Disorders: The Clinical Spectrum Beyond Tics. International Review of Neurobiology Vol 134. 2017, σσ. 1461-1490.
9. Cavanna, Andrea E., και συν. The cognitive neuropsychiatry of Tourette syndrome. Cognitive Neuropsychiatry Vol 25 Issue 4. April 2020, σσ. 254-268.
10. Cavanna, Andrea E. και Rickards, Hugh. The psychopathological spectrum of Gilles de la Tourette syndrome. Neuroscience & Biobehavioral Reviews Vol 37 Issue 6. July 2013, σσ.
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12. Schahill, Lawrence, Specht, Matthew και Page, Christopher. The prevalence of tic disorders and clinical characteristics in children. Journal of Obsessive-Compulsive and Related Disorders. October 2014, σσ. 394-400.
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14. Robertson, Mary M. The prevalence and epidemiology of Gilles de la Tourette syndrome: Part 1: The epidemiological and prevalence studies. Journal of Psychosomatic Research, Volume 65,Issue 5. November 2008, σσ. 461-472.
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16. Kurlan, R., και συν. Prevalence of tics in schoolchildren and association with placement in special education. Neurology. 23 Oct 2001, σσ. 1383-1388.
E. t.k.adelais@gmail.com
Correspondence
Adelais Tzortzopoulou
T. +306945257431
E. t.k.adelais@gmail.com
Transumbilical Laparoscopically Assisted Appendicectomy (TULAA) in children: A minimally invasive method of treating acute appendicitis
Ioannis Skondras, Adelais Tzortzopoulou, Georgios Kapouleas, Alexander Passalides.
Abstract
Introduction: Transumbilical Laparoscopically Assisted Appendicectomy (TULAA) is a safe, fast and cost-effective, minimally invasive method of treating acute appendicitis in children.
Material and Method: This is a retrospective study involving 72 children, aged 6 to 16 years with acute appendicitis, who underwent transumbilical laparoscopic assisted appendicectomy (TULAA) during 2018-2021. The time of hospitalization of the patients as well as the postoperative complications were evaluated.
Results: 65/72 patients had simple, non complicated appendicitis and 7/72 gangrenous appendicitis without rupture. In 3 patients the operation was converted to laparoscopic and in one of them to open. The average duration of the operation was 45 minutes. The average of hospitalization time was 52 hours. The cost of the operation was the same as the open procedure, as the use of special laparoscopic equipment is not required. Finally, the postoperative complications were very few: only 4 site surgical infections of the umbilical wound (SSIs) and 1 postoperative abscess were reported.
Conclusion: Transumbilical laparoscopically assisted appendicectomy (TULAA) can be safely used as a primary treatment for children with acute appendicitis, with great benefits.
2nd Pediatric Surgery Department “P. & A. Kyriakou” Children's Hospital, Athens, Greece
1. Noviello C, Romano M, Martino A, Cobellis G, Transumbilical Laparoscopic-Assisted Appendectomy in the Treatment of acute uncomplicated appendicitis in children, Gastroenterology Research and Practice, Vol2015, doi: 10.1155/2015/949162
2. Duebbers M, Nikolaou E, Fuchs H, Fischer J, Alakus H, Leers J, Bruns C, Cernalanu G, Update on Transumbilical Single-Incision Laparoscopic Assisted Appendectomy (TULAA)Which Children benefit and what are the complications?, Klin Pediatr 2018, doi: 10.1055/s0044-101622
3. Hernandez-Martin S, Ayoso L, Molina A.Y, Pison J, Martinez-Bermejo M.A, Perez-Martina A., Transumbilical laparoscopic-assisted appendectomy in children: is it worth it?, Surg Endosc 2017, doi:10.1007/s00464-017-5618-6
4. Semm K (1983) Endoscopic appendectomy. Endoscopy 15:59–64
6 Koizumi N, Kobayashi H, Nakase Y, Takagi T, Fukumoto K, Efficacy of transumbilical laparoscopic-assisted appendectomy for appendicitis: a four-year experience at a single center, Surg Today 2014, doi:10.1007/s00595-014-1034-x
E. vikigetsi@gmail.com
Correspondence
Vasiliki Getsi
Neochoropoulos of Ioannina, 45500
T. +302651080785, 6945398479
E. vikigetsi@gmail.com
Association between IgA vasculitis and COVID-19 disease. A case report in a 9 years old boy
The last two years, with more than 468.6 million cases and 6.09 million deaths worldwide, COVID-19 disease is a daily concern of the international scientific community. Various complications of the disease have been reported and a number of relevant studies have been published. It is now well documented that SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) causes vasculitis of various types. In the present study a case of a 9 years old boy who developed IgA vasculitis after COVID-19 disease is presented, and a review of recent literature on the association of COVID-19 disease with IgA vasculitis is attempted, as well as the role of SARS-CoV-2 virus in the pathogenesis of this disease.
Key words: COVID-19, SARS-CoV-2, IgA vasculitis (purpura Henoch-Schönlein)
Margarita Papasavva
Dimitra Savvidou
Vasilios Grammeniatis
Ilias Lolos
Aggelos Ntritsos
Vasiliki Getsi
Pediatric Derartment of the General Hospital of Ioannina “G. Chatzikosta”
Kawasaki,
(IgA1)
ορούς ασθενών είναι γαλακτοζυλιωμένες
Βιβλιογραφία
1. Sunmeet Sandhu, Satish Chand, Anuj Bhatnagar, Rajeshwari Dabas, Showkat Bhat, Harish Kumar, et al. Possible association between IgA vasculitis and COVID-19. Dermatol Ther. 2021 Jan;34(1):e14551. doi: 10.1111/dth.14551.
2. Jedlowski PM, Jedlowski MF. Coronavirus disease 2019 associated immunoglobulin A vasculitis/Henoch-Schönlein purpura: A case report and review. J Dermatol. 2022 Jan;49(1):190-196. doi: 10.1111/1346-8138.16211.
3. Allez M, Denis B, Bouaziz J-D, et al. COVID-19 related IgA vasculitis. Arthritis Rheumatol (Hoboken, NJ). 2020;72:1952-1953.
4. Suso AS, Mon C, Alonso IO, et al. IgA vasculitis with nephritis (Henoch-Schönlein purpura) in a COVID-19 patient. Kidney Int Rep. 2020;5:2074-2078.
5. Saeed Soleiman-Meigooni, Ramin Yaghmayee, Ramin Hamidi-Farahani, Mousa Ahmadi, Allahyar Taheri, Ali Asgari, et al. Henoch-Schoenlein Purpura Following Severe Acute Respiratory Syndrome Coronavirus-2 Infection: A Case Report, Nephro-Urology Monthly: 13(4); e 116227.
6. Brett Hoskins, Nicholas Keeven, Mary Dang, Emily Keller, Rajeev Nagpal. A Child with COVID-19 and Immunoglobulin A Vasculitis. Pediatr Ann; 50(1): e44-e48. doi: 10.3928/19382359-20201211-01.
7. Ramiz Ziyara , Amanda Thompson , Ben Liu. Henoch-Schönlein Purpura in a COVID-19Positive Child With Abdominal Pain and PIMS-TS. Clin Pediatr (Phila). 2022 Jan;61(1):5-8. doi: 10.1177/00099228211040660.
8. Borocco C, Lafay C, Plantard I, Gottlieb J, Koné-Paut I, Galeotti C. SARS-CoV-2-associated Henoch-Schönlein purpura in a 13-year-old girl. Arch Pediatr. 2021 Oct;28(7):573-575. doi: 10.1016/j.arcped.2021.06.004.
9. Dalal Anwar AlGhoozi, Haya Mohammed AlKhayyat. A child with Henoch-Schonlein purpura secondary to a COVID-19 infection. BMJ case reports v.14 no.1 , 2021, pp.e239910. doi.org/10.1136/bcr-2020-239910.
10. Georges El Hasbani, Ali T Taher, Ali S M Jawad, Imad Uthman. Henoch-Schönlein purpura: Another COVID-19 complication. Pediatr Dermatol. 2021 Sep;38(5):1359-1360. doi: 10.1111/pde.14699.
11. Hareem Farooq, Muhammad Aemaz Ur Rehman, Abyaz Asmar, Salman Asif, Aliza Mushtaq, Muhammad Ahmad Qureshi. The pathogenesis of COVID-19-induced IgA nephropathy and IgA vasculitis: A systematic review. J Taibah Univ Med Sci. 2022 Feb; 17(1): 1–13. doi: 10.1016/j.jtumed.2021.08.012.
12. Maryam Piram, Alfred Mahr. Epidemiology of immunoglobulin A vasculitis (HenochSchönlein): current state of knowledge. Curr Opin Rheumatol. 2013 Mar;25(2):171-8. doi: 10.1097/BOR.0b013e32835d8e2a.
13. Kalai Wong, Mir Umer Farooq Alam Shah, Maman Khurshid, Irfan Ullah, Muhammad Junaid Tahir, Zohaib Yousaf. COVID-19 associated vasculitis: A systematic review of case reports and case series. Ann Med Surg (Lond). 2022 Feb; 74: 103249. doi: 10.1016/j. amsu.2022.103249.
14. Shab E Gul Rahim, Jonathan T Lin, John C Wang. A case of gross hematuria and IgA nephropathy flare-up following SARS-CoV-2 vaccination. Kidney Int. 2021 Jul;100(1):238. doi: 10.1016/j.kint.2021.04.024.
15. Lavinia Negrea, Brad H. Rovin. Gross hematuria following vaccination for severe acute respiratory syndrome coronavirus 2 in 2 patients with IgA nephropathy. Kidney Int. 2021
17. Michel Obeid, Craig Fenwick, Giuseppe Pantaleo. Reactivation of IgA vasculitis after COVID-19 vaccination. Lancet Rheumatol. 2021 Sep;3(9):e617. doi: 10.1016/S26659913(21)00211-3.
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20. M Tomana, K Matousovic, B A Julian, J Radl, K Konecny, J Mestecky. Galactose-deficient IgA1 in sera of IgA nephropathy patients is present in complexes with IgG. Kidney Int. 1997 Aug;52(2):509-16. doi: 10.1038/ki.1997.361.
21. Z Moldoveanu, R J Wyatt, J Y Lee, M Tomana, B A Julian, J Mestecky, et al. Patients with IgA nephropathy have increased serum galactose-deficient IgA1 levels. Kidney Int . 2007 Jun;71(11):1148-54. doi: 10.1038/sj.ki.5002185.
22. Keith K Lau, Robert J Wyatt, Zina Moldoveanu, Milan Tomana, Bruce A Julian, Ronald J Hogg, et al. Serum levels of galactose-deficient IgA in children with IgA nephropathy and Henoch-Schönlein purpura. Pediatr Nephrol. 2007 Dec;22(12):2067-72. doi: 10.1007/ s00467-007-0623-y.
Correspondence
Vasileios Giapros
NICU, University Hospital of Ioannina, 45110, Ioannina E. vgiapros@uoi.gr
Congenital Hyperinsulinism: A case study and review of the literature
E. Domouzoglou, D. Rallis, T. Palianopoulos, V. Giapros, F. Balomenou
Abstract
Introduction: Congenital hyperinsulinism (CHI) is a heterogenous group of clinical, genetic, and morphological features that are characterized by a severe derangement in insulin secretion by the pancreatic b-cells, leading to hypoglycemia. CHI is the most common and severe cause of hypoglycemia in neonates and infants, with a varying clinical picture.
Case report: We report the case of a neonate with a persistent hypoglycemia since birth, that was diagnosed based on clinical and laboratory finding with CHI and was successfully treated with diazoxide.
Conclusions: The early diagnosis and treatment of hypoglycemia is crucial for the prevention of the permanent cerebral injury.
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6. Senniappan S, Shanti B, James C, Hussain K. Hyperinsulinaemic hypoglycaemia: genetic mechanisms, diagnosis and management. J Inherit Metab Dis 2012;35:589–601.
7. Yau D, Laver TW, Dastamani A, Senniappan S, Houghton JAL, Shaikh G, et al. Using referral rates for genetic testing to determine the incidence of a rare disease: the minimal incidence of congenital hyperinsulinism in the UK is 1 in 28,389. PLoS One 2020;15:e0228417.
8. Demirbilek H, Hussain K. Congenital hyperinsulinism: diagnosis and treatment update. J Clin Res Pediatr Endocrinol 2017;9: 69–87.
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et moyens d’ y remédier),
των αναπνευστικών οργάνων
παρά τοις παισίν), το 1882, και στην
επιρροή της οδοντοφυΐας στα νοσήματα της
βρεφικής ηλικίας (Du rôle de la dentition dans la pathologie enfantine / Περί της
επιρροής της οδοντοφυΐας επί των νόσων
βρεφικής ηλικίας), το 1883. Πρέπει να
επισημανθεί επίσης ότι ο καθηγητής Ζίννης, ενήμερος
Du traitement de la diarrhée chronique chez les enfants
Διαμαντής Α.: “Αναστάσιος Ζίννης (1829-1899). Ο πρωτοπόρος της
Ελλάδα”, Ενδοσκοπήσεις, 2021; 56: 50-56.
Ζίννης Α.: “Έκθεσις των κατά
Αθήνησι 1861.
Α.: “Έκθεσις
Materia Medica Greca, 1989; 14(1): 97-101.
ΣΥΝΑΔΕΛΦΙΚΑ
1.
2.
3. Βραβευμένες
4. Ερευνητικές μελέτες
5.
6.
7. Επίκαιρα θέματα
τραπεζών
8. Θέματα εκπαίδευσης και οργάνωσης υγείας
9. Ενδιαφέρουσες περιπτώσεις
10. Σύντομα νέα
11. Βραχείες δημοσιεύσεις
12. Επιστολές προς τη σύνταξη
13.
14.
•
International Committee of Medical Journal Editors/ Uniform Requirements for Manuscripts Submitted to Biomedical Journals, (www.icmje.org και www.icmje.org/icmje.pdf).
Cumulated Index Medicus [List of Journals Indexed in Index Medicus (www.nlm.nih.goν/bsd/ uniform_requirements.html)].
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Συμπληρωματικό
Flyvbjerg Α. Role of growth hormone, insulin-like growth factors (IGFs) and IGF-binding proteins in the renal complications of diabetes. Kidney Ιnt 1997;52 (60 Suppl):S12-S19.
National Institutes of Health Consensus Deνelopment Conference. Neurofibromatosis conference statement. Arch Neurol1988;45:575-578. Προσδιορισμός
Schreiner GF, Lange L. Ethanol modulation of macrophage influx in glomerulonephritis [Abstract]. J Am Soc Nephrol 1991;2:562.
Should antileukotriene therapies be used instead of inhaled corticosteroids in asthma?
[Editorial]. Am J Respir Crit Care Med 1998;158:1697-1701.
Clark AG, Barratt ΤΜ. Steroid-responsiνe nephrotic syndrome. Ιn: Barratt ΤΜ, Arner ED, Harmon WE, editors. Pediatric Nephrology. 4th ed. Baltimore: Lippincott William Wilkins; 1999. p. 742.
Σύγγραμμα ή μονογραφία:
Gorlin RJ, Cohen ΜΜ, Leνin LS. Syndromes of the head and neck. 3rd ed. New York: Oxford Uniνersity Press; 1990.
Δημοσίευση
Bauer ΑW. The two definitions of bacterial resistance. In: Smith AJ, Rogers CA, eds. Proceedings of the Third International Congress of Chemotherapy; 1962 May 29-31; New York: International Society of Chemotherapy; 1963. p. 484-500.
Διδακτορική
Αθηνών; 1979.
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III. CD-ROM
Andersoη SC, Poulsen ΚΒ. Anderson’s electronic atlas of hematology [CD-ROM]. Philadelphia: Lippincott Williams & Wilkins; 2002.
IV. ΣΤΟ ΔΙΑΔΙΚΤΥΟ
Άρθρο σε περιοδικό:
Abood S. Quality improνement initiatiνe in nursiηg homes: the ΑΝΑ acts in an adνisory role. Am J Nurs [Internet]. 2002 Jun:
