Appl i cat i onsofCel lCul t ur e
One oft he mostessent i alt ool si n cel l ul arand mol ecul arbi ol ogyi scel lcul t ur e,whi ch of f er s super i ormodelsyst emsf orst udyi ngt het ypi calphysi ol ogyandbi ochemi st r yofcel l s( suchas met abol i cst udi es,agei ng) ,t heef f ect sofdr ugsandt oxi csubst ancesont hecel l s,andmut agenesi sandcar ci nogenesi s.Addi t i onal l y ,i ti sut i l i sedf orbi ol ogi calcompoundmanuf act ur eonabi g scal easwel lasdr ugr esear chandscr eeni ng( e. g. ,vacci nes,t her apeut i cpr ot ei ns) .Themai n benef i tofempl oyi ngcl onalcel l si ncel lcul t ur ef oranyoft heseappl i cat i onsi st hest abi l i t yand r epr oduci bi l i t yoft her esul t st hatmayobt ai n.
VACCI NE PRODUCTI ON: Thedevel opmentandmanuf act ur i ngofvacci nesar eone oft he mostcr uci alappl i cat i onsofcel lcul t ur e.The pol i o vacci newasevent ual l ydevel opedbecauseoft heabi l i t yt o gr ow vastquant i t i esofvi r usi ncel lcul t ur e,andcel l sar e bei ngempl oyedext ensi vel yt odayt omakevacci nat i onsf or manyot herdi seases.
CANCER RESEARCH: Radi at i on,chemi cal s,and vi r usesar ej usta f ew mechani sms t hatcan t ur n nor malcel l si nt o cancer ous ones. Then,t hesecel l scanbeut i l i sedt oexami necancermor e t hor oughl yandt r ypr ospect i vef r esht her api es.
MOLECULAR AND CELLULAR BI OLOGY: One oft he mostcr i t i calt ool si n cel l ul arand mol ecul ar bi ol ogy i s cel lcul t ur e,whi ch of f er s appr opr i at e model syst emsf orst udyi ngt het ypi calphysi ol ogyandbi ochemi st r yofcel l s( suchasmet abol i cst udi es,agei ng) ,t heef f ect s ofvar i oust oxi csubst ancesont hecel l s,andmut agenesi s and car ci nogenesi s.The uni f or mi t yand r epr oduci bi l i t yof t hedat aacqui r edf r om abat chofcl onalcel l si st hepr i mar y benef i t of cel l cul t ur ef or any of t hese appl i cat i ons.